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Revenue - Summary of Revenue Recognized, Transaction Price as a Result of Recognition of Milestones, and Estimated Revenue Expected to Be Recognized (Parenthetical) (Details) $ in Thousands | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2026 USD ($) Milestones | Mar. 31, 2025 USD ($) | Dec. 31, 2025 USD ($)
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue |  | $ 26,523 | $ 219 |
Novo Collaboration Agreement Member |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
One-time non-refundable upfront payment received |  | $ 195,000 |  |
Number of milestones probable to achievement | Milestones |  | 2 |  |
Variable consideration |  | $ 94,000 |  |
Revenue | [1] | 71,900 |  |
Novo Collaboration Agreement Member | R&D Programs and Manufacturing Services |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
One-time non-refundable upfront payment received |  | 153,800 |  |
Variable consideration |  | 10,300 |  | $ 18,600
Novo Collaboration Agreement Member | Material Right |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
One-time non-refundable upfront payment received |  | 41,200 |  |
Novo Collaboration Agreement Member | R&D Programs |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
One-time non-refundable upfront payment received |  | 15,700 |  | $ 26,800
Novo Collaboration Agreement Member | Collaboration milestones |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
One-time non-refundable upfront payment received |  | 500 |  |
Novo Collaboration Agreement Member | Discovery Research Milestones |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Variable consideration |  | $ 2,000 |  |
[1] | For the three months ended March 31, 2026, the Company recognized revenue of $26.5 million, which was comprised of $10.3 million variable consideration related to research services for the four R&D Programs and manufacturing services, $15.7 million recognition of deferred revenue for the one-time, non-refundable upfront payment, and $0.5 million milestone revenue recognized on the two milestones discussed above. The Company recognized $26.8 million of the one-time, non-refundable upfront payment and $18.6 million variable considerations related to research services for the four R&D Programs and manufacturing services during the year ended December 31, 2025.

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