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v3.23.2

Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 6 Months Ended | 12 Months Ended | 66 Months Ended
--- | --- | --- | ---
Jun. 30, 2023 | Jun. 30, 2022 | Dec. 31, 2022 | Jun. 30, 2023
Cash flows from operating activities |  |  |  |
Net loss | $ (78,779) | $ (91,585) |  |
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |  |
Depreciation and amortization | 269 | 277 |  |
Stock-based compensation | 14,301 | 11,660 |  |
Issuance of PIK interest debt | 1,772 | 1,713 |  |
Accrued interest on revenue interest financing liability | 10,550 | 2,657 |  |
Amortization of debt discount | 769 | 1,049 |  |
Other | 1,157 | 874 |  |
Changes in operating assets and liabilities: |  |  |  |
Prepaid expenses and other current assets | (3,633) | 1,402 |  |
Accounts payable and accrued expenses (includes changes in related party amounts of $264 and $1,102, respectively) | (8,447) | 2,865 |  |
Accrued clinical trial expenses |  | (1,061) |  |
Accrued interest | 73 | 88 |  |
Operating right-of-use assets and lease liabilities | 99 | (293) |  |
Other long-term assets |  | (119) |  |
Net cash used in operating activities | (61,869) | (70,473) |  |
Cash flows from investing activities |  |  |  |
Cash paid for property, plant and equipment | (220) | (495) |  |
Net cash used in investing activities | (220) | (495) |  |
Cash flows from financing activities |  |  |  |
Proceeds from issuance of common stock from exercise of stock options | 111 |  |  |
Net proceeds from underwritten public offering | 141,390 |  |  |
Net proceeds from revenue interest financing transaction |  | 95,446 | $ 95,400 |
Net cash provided by financing activities | 155,574 | 95,446 |  |
Net increase in cash and cash equivalents and restricted cash | 93,485 | 24,478 |  |
Cash and cash equivalents and restricted cash - beginning of period | 155,890 | 183,419 | 183,419 |
Cash and cash equivalents and restricted cash - end of period | 249,375 | 207,897 | $ 155,890 | $ 249,375
Supplemental disclosure of cash flow information |  |  |  |
Interest paid | 5,310 | 2,920 |  |
Supplemental disclosure of noncash investing and financing activities |  |  |  |
Inventory purchases included in accounts payable and accrued expenses | 3,561 |  |  |
Property and equipment purchases included in accounts payable and accrued expenses |  | 16 |  |
Settlement of ESPP liability in common stock | 856 | 515 |  |
Settlement of 401(k) liability in common stock | 456 | 254 |  |
Operating lease liabilities arising from obtaining right-of-use assets |  | $ 554 |  |
At-the-Market Offering Program |  |  |  |
Cash flows from financing activities |  |  |  |
Net proceeds from issuance of common stock | $ 14,073 |  |  | $ 38,700

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