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Statements of Stockholders' Equity (Unaudited) - USD ($) $ in Thousands | Total | Underwritten Public Offering | At-the-Market Offering Program | Common Stock | Common Stock Underwritten Public Offering | Common Stock At-the-Market Offering Program | Treasury Stock | Additional Paid-in Capital | Additional Paid-in Capital Underwritten Public Offering | Additional Paid-in Capital At-the-Market Offering Program | Accumulated Deficit
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Beginning balance at Dec. 31, 2021 | $ 72,156 |  |  | $ 3 |  |  |  | $ 601,523 |  |  | $ (529,370)
Beginning balance, shares at Dec. 31, 2021 |  |  |  | 30,511,226 |  |  | 1 |  |  |  |
Cashless exercise of common stock warrants, shares |  |  |  | 7,359,285 |  |  | 18 |  |  |  |
401(k) matching contribution | 254 |  |  |  |  |  |  | 254 |  |  |
401(k) matching contribution, shares |  |  |  | 16,756 |  |  |  |  |  |  |
Vesting of restricted shares, shares |  |  |  | 222,595 |  |  |  |  |  |  |
Stock-based compensation | 5,775 |  |  |  |  |  |  | 5,775 |  |  |
ESPP shares issued | 515 |  |  |  |  |  |  | 515 |  |  |
ESPP shares issued, shares |  |  |  | 39,951 |  |  |  |  |  |  |
Net loss | (40,665) |  |  |  |  |  |  |  |  |  | (40,665)
Ending balance at Mar. 31, 2022 | 38,035 |  |  | $ 3 |  |  |  | 608,067 |  |  | (570,035)
Ending balance, shares at Mar. 31, 2022 |  |  |  | 38,149,813 |  |  | 19 |  |  |  |
Beginning balance at Dec. 31, 2021 | 72,156 |  |  | $ 3 |  |  |  | 601,523 |  |  | (529,370)
Beginning balance, shares at Dec. 31, 2021 |  |  |  | 30,511,226 |  |  | 1 |  |  |  |
Net loss | (91,585) |  |  |  |  |  |  |  |  |  |
Ending balance at Jun. 30, 2022 | (7,000) |  |  | $ 3 |  |  | $ 19 | 613,952 |  |  | (620,955)
Ending balance, shares at Jun. 30, 2022 |  |  |  | 38,372,403 |  |  |  |  |  |  |
Beginning balance at Mar. 31, 2022 | 38,035 |  |  | $ 3 |  |  |  | 608,067 |  |  | (570,035)
Beginning balance, shares at Mar. 31, 2022 |  |  |  | 38,149,813 |  |  | 19 |  |  |  |
Vesting of restricted shares, shares |  |  |  | 222,590 |  |  |  |  |  |  |
Stock-based compensation | 5,885 |  |  |  |  |  |  | 5,885 |  |  |
Net loss | (50,920) |  |  |  |  |  |  |  |  |  | (50,920)
Ending balance at Jun. 30, 2022 | (7,000) |  |  | $ 3 |  |  | $ 19 | 613,952 |  |  | (620,955)
Ending balance, shares at Jun. 30, 2022 |  |  |  | 38,372,403 |  |  |  |  |  |  |
Beginning balance at Dec. 31, 2022 | $ (74,814) |  |  | $ 3 |  |  |  | 652,276 |  |  | (727,093)
Beginning balance, shares at Dec. 31, 2022 | 41,468,871 |  |  | 41,468,871 |  |  | 19 |  |  |  |
401(k) matching contribution | $ 456 |  |  |  |  |  |  | 456 |  |  |
401(k) matching contribution, shares |  |  |  | 52,130 |  |  |  |  |  |  |
Vesting of restricted shares, shares |  |  |  | 414,119 |  |  |  |  |  |  |
Stock-based compensation | 7,048 |  |  |  |  |  |  | 7,048 |  |  |
ESPP shares issued | 856 |  |  |  |  |  |  | 856 |  |  |
ESPP shares issued, shares |  |  |  | 121,801 |  |  |  |  |  |  |
Issuance of common stock, shares |  |  |  |  |  | 1,514,219 |  |  |  |  |
Issuance of common stock, net |  |  | $ 14,073 |  |  | $ 1 |  |  |  | $ 14,072 |
Net loss | (37,814) |  |  |  |  |  |  |  |  |  | (37,814)
Ending balance at Mar. 31, 2023 | (90,195) |  |  | $ 4 |  |  |  | 674,708 |  |  | (764,907)
Ending balance, shares at Mar. 31, 2023 |  |  |  | 43,571,140 |  |  | 19 |  |  |  |
Beginning balance at Dec. 31, 2022 | $ (74,814) |  |  | $ 3 |  |  |  | 652,276 |  |  | (727,093)
Beginning balance, shares at Dec. 31, 2022 | 41,468,871 |  |  | 41,468,871 |  |  | 19 |  |  |  |
Net loss | $ (78,779) |  |  |  |  |  |  |  |  |  |
Ending balance at Jun. 30, 2023 | $ 17,600 |  |  | $ 5 |  |  | $ 19 | 823,467 |  |  | (805,872)
Ending balance, shares at Jun. 30, 2023 | 56,639,085 |  |  | 56,639,085 |  |  |  |  |  |  |
Beginning balance at Mar. 31, 2023 | $ (90,195) |  |  | $ 4 |  |  |  | 674,708 |  |  | (764,907)
Beginning balance, shares at Mar. 31, 2023 |  |  |  | 43,571,140 |  |  | 19 |  |  |  |
Issuance of common stock from exercise of stock options | 111 |  |  |  |  |  |  | 111 |  |  |
Issuance of common stock from exercise of stock options, shares |  |  |  | 15,000 |  |  |  |  |  |  |
Vesting of restricted shares | 6 |  |  |  |  |  |  | 6 |  |  |
Vesting of restricted shares, shares |  |  |  | 259,194 |  |  |  |  |  |  |
Stock-based compensation | 7,253 |  |  |  |  |  |  | 7,253 |  |  |
Issuance of common stock, shares |  |  |  |  | 12,793,750 |  |  |  |  |  |
Issuance of common stock, net |  | $ 141,390 |  |  | $ 1 |  |  |  | $ 141,389 |  |
Net loss | (40,965) |  |  |  |  |  |  |  |  |  | (40,965)
Ending balance at Jun. 30, 2023 | $ 17,600 |  |  | $ 5 |  |  | $ 19 | $ 823,467 |  |  | $ (805,872)
Ending balance, shares at Jun. 30, 2023 | 56,639,085 |  |  | 56,639,085 |  |  |  |  |  |  |

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