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Intangible Assets (Details) (USD $) | Dec. 31, 2012 | Dec. 31, 2011
--- | --- | ---
Intangible Assets |  |
Less: accumulated amortization | $ (261,928) | $ (291,658)
Intangible assets, net | 573,731 | 899,480
License agreements [Member] |  |
Intangible Assets |  |
Finite-lived intangible assets, gross | 772,230 | 899,231
Patents [Member] |  |
Intangible Assets |  |
Finite-lived intangible assets, gross | $ 63,429 | $ 291,907

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