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Note Payable and Term Loan Agreement - Term Loan Agreement and Revenue Interest Agreement (Details) - USD ($) |  |  | 12 Months Ended |  |
--- | --- | --- | --- | --- | ---
Nov. 12, 2014 | Oct. 05, 2012 | Dec. 31, 2015 | Dec. 31, 2014 | Nov. 13, 2014
Debt Instrument [Line Items] |  |  |  |  |
Shares of common stock sold |  |  | 29,984,591 | 19,488,814 |
Value of common stock sold |  |  | $ 299,846 | $ 194,888 |
PDL |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |
Shares of common stock sold | 643,382 |  |  |  |
Value of common stock sold | $ 1,750,000 |  |  |  |
Public offering price (in dollars per share) | $ 2.72 |  |  |  |
Three Peaks |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |
Shares of common stock sold | 1,375,969 |  |  |  |
Value of common stock sold | $ 3,550,000 |  |  |  |
Public offering price (in dollars per share) | $ 2.58 |  |  |  |
Term Loan | Three Peaks |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |
Term | 6 years |  |  |  |
Interest payable | 9.00% |  |  |  |
Face amount | $ 25,000,000 |  |  |  |
Basis spread on fixed rate, option 1 | LIBOR |  |  |  |
Basis spread on fixed rate, option 2 | 1.00% |  |  |  |
Effective interest rate (as a percent) |  |  | 10.00% | 10.00% | 10.00%
Optional future additional borrowing | $ 7,000,000 |  |  |  |
Upon certain events, the percentage of outstanding principal amount of the Term Loan the Company has the option to prepay and the lender has a right to demand payment for on or prior to the first anniversary of the applicable Closing Date | 120.00% |  |  |  |
Upon certain events, the percentage of outstanding principal amount of the Term Loan the Company has the option to prepay and the lender has a right to demand payment for after the first anniversary but before the second anniversary of the applicable Closing Date | 135.00% |  |  |  |
Upon certain events, the percentage of outstanding principal amount of the Term Loan the Company has the option to prepay and the lender has a right to demand payment for after the second anniversary but before the third anniversary of the applicable Closing Date | 150.00% |  |  |  |
Upon certain events, the internal rate of return of the outstanding principal amount of the Term Loan the Company has the option to prepay and the lender has a right to demand after the third anniversary of the applicable Closing Date | 16.25% |  |  |  |
Upon certain events, the additional percentage of the originally advanced Term Loan amount owed | 3.00% |  |  |  |
Revenue Interest Purchase Agreement | PDL |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |
Term |  | 8 years |  |  |
Revenue Interest Purchase Agreement | Three Peaks |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |
Term | 10 years |  | 10 years |  |
Royalty percentage on net revenue | 3.75% |  |  |  |
Revenue Interest Purchase Agreement | Three Peaks | Maximum |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |
Royalty percentage on net revenue | 4.80% |  |  |  |
Royalty revenue per year | $ 30,000,000 |  |  |  |

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