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Stock Incentive Plan - Non-vested Share-based Activity (Details) - Employee Consultants and Directors Stock Options [Member] - $ / shares | 12 Months Ended
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Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Non-vested share-based payment activity with employees |  |  |
Number of non-vested options outstanding at the beginning of the period (in shares) | 2,121,319 | 1,179,969 | 1,159,486
Number of non-vested options granted (in shares) | 1,298,355 | 1,529,850 | 946,250
Number of options vested (in shares) | (692,253) | (512,562) | (635,289)
Number of non-vested options forfeited (in shares) | (94,777) | (75,938) | (290,478)
Number of non-vested options outstanding at the end of the period (in shares) | 2,632,644 | 2,121,319 | 1,179,969
Weighted average grant-date fair value of non-vested options outstanding at the beginning of the period (in dollars per share) | $ 6.72 | $ 4.21 | $ 3.37
Weighted average grant-date fair value of options granted (in dollars per share) | 19.99 | 7.67 | 4.31
Weighted average grant-date fair value of options vested (in dollars per share) | (6.49) | (4.21) | (3.32)
Weighted average grant-date fair value of non-vested options forfeited (in dollars per share) | (6.29) | (3.74) | (3.12)
Weighted average grant-date fair value of non-vested options outstanding at the end of the period (in dollars per share) | $ 13.33 | $ 6.72 | $ 4.21

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- Definition Gross number of share options (or share units) granted during the period. + References No definition available. + Details
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- Definition The weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d)(1) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Number of non-vested options outstanding. + References No definition available. + Details
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- Definition Number of non-vested options forfeited. + References No definition available. + Details
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- Definition Weighted average grant-date fair value of non-vested options forfeited. + References No definition available. + Details
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- Definition Weighted average grant-date fair value of non-vested options outstanding. + References No definition available. + Details
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- Definition Number of options vested. + References No definition available. + Details
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- Details
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