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Stockholders' Equity (Deficit) - Public Offering (Details) |  |  |  |  |  |  | 12 Months Ended
--- | --- | --- | --- | --- | --- | --- | ---
Nov. 16, 2017 USD ($) $ / shares shares | Oct. 13, 2016 USD ($) shares | Oct. 07, 2016 item $ / shares shares | Aug. 26, 2015 USD ($) $ / shares shares | Feb. 13, 2015 USD ($) $ / shares shares | Feb. 05, 2015 $ / shares shares | Dec. 31, 2017 USD ($) $ / shares shares | Dec. 31, 2016 USD ($) $ / shares shares | Dec. 31, 2015 USD ($)
Shares of common stock sold |  |  |  |  |  |  | 34,350,329 | 33,008,865 |
Par value of common stock | $ / shares |  |  |  |  |  |  | $ 0.01 | $ 0.01 |
Public offering price (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 28.30 | $ 9.00 |
Net proceeds from issuance of common stock | $ |  |  |  |  |  |  | $ 15,662,905 | $ 18,668,092 | $ 30,968,386
Offering expenses | $ |  |  |  | $ 300,000 |  |  |  |  |
February 2015 Offering |  |  |  |  |  |  |  |  |
Shares of common stock sold |  |  |  |  | 5,437,200 | 4,728,000 |  |  |
Par value of common stock | $ / shares |  |  |  |  | $ 2.75 | $ 0.01 |  |  |
Public offering price (in dollars per share) | $ / shares |  |  |  |  |  | $ 2.75 |  |  |
Number of days to underwriter to sell additional common shares |  |  |  |  |  | 30 days |  |  |
Underwriting discounts, commissions and other estimated offering expenses | $ |  |  |  |  | $ 15,000,000 |  |  |  |
Offering expenses paid | $ |  |  |  |  | $ 1,400,000 |  |  |  |
August 2015 Offering |  |  |  |  |  |  |  |  |
Shares of common stock sold |  |  |  | 4,861,111 |  |  |  |  |
Par value of common stock | $ / shares |  |  |  | $ 3.60 |  |  |  |  |
Gross proceeds from issuance of common stock | $ |  |  |  | $ 17,500,000 |  |  |  |  |
October 2016 Offering |  |  |  |  |  |  |  |  |
Shares of common stock sold |  |  | 2,333,334 |  |  |  |  |  |
Public offering price (in dollars per share) | $ / shares |  |  | $ 7.50 |  |  |  |  |  |
Number of days to underwriter to sell additional common shares |  |  | 30 days |  |  |  |  |  |
October 2016 Offering | Directors and officers |  |  |  |  |  |  |  |  |
Shares of common stock sold |  |  | 32,666 |  |  |  |  |  |
Number of directors and officers who purchased common stock | item |  |  | 5 |  |  |  |  |  |
October 2016 Offering inclusive of over-allotment option |  |  |  |  |  |  |  |  |
Shares of common stock sold |  | 2,683,334 |  |  |  |  |  |  |
Net proceeds from issuance of common stock | $ |  | $ 18,670,000 |  |  |  |  |  |  |
November 2017 Offering |  |  |  |  |  |  |  |  |
Shares of common stock sold | 700,000 |  |  |  |  |  |  |  |
Number of days to underwriter to sell additional common shares | 30 days |  |  |  |  |  |  |  |
Offering expenses | $ | $ 15,650,000 |  |  |  |  |  |  |  |
Underwriting Agreement |  |  |  |  |  |  |  |  |
Shares of common stock sold | 255,000 | 350,000 | 350,000 |  |  | 709,200 |  |  |
ESSEX | November 2017 Offering |  |  |  |  |  |  |  |  |
Shares of common stock sold | 1,000,000 |  |  |  |  |  |  |  |
Public offering price (in dollars per share) | $ / shares | $ 21.00 |  |  |  |  |  |  |  |

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