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CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN SHAREHOLDERS EQUITY - USD ($) $ in Thousands | Common Stock [Member] | Additional Paid-in Capital [Member] | Accumulated Deficit [Member] | Total
--- | --- | --- | --- | ---
Beginning Balance at Dec. 31, 2017 | $ 343 | $ 153,168 | $ (128,329) | $ 25,182
Increase (Decrease) in Stockholders' Equity |  |  |  |
Net Loss |  |  | (13,066) | (13,066)
Issuance of common stock | 35 | 132,671 |  | 132,706
Stock-based compensation |  | 3,770 |  | 3,770
Exercise of stock options and employee stock purchase plan | 5 | 1,906 |  | 1,911
Ending Balance at Jun. 30, 2018 | 383 | 291,515 | (141,395) | 150,503
Beginning Balance at Mar. 31, 2018 | 346 | 155,313 | (133,968) | 21,692
Increase (Decrease) in Stockholders' Equity |  |  |  |
Net Loss |  |  | (7,428) | (7,428)
Issuance of common stock | 35 | 132,671 |  | 132,706
Stock-based compensation |  | 2,041 |  | 2,041
Exercise of stock options | 2 | 1,490 |  | 1,492
Ending Balance at Jun. 30, 2018 | 383 | 291,515 | (141,395) | 150,503
Beginning Balance at Dec. 31, 2018 | 389 | 297,319 | (150,726) | 146,982
Increase (Decrease) in Stockholders' Equity |  |  |  |
Net Loss |  |  | (16,526) | (16,526)
Stock-based compensation |  | 4,989 |  | 4,989
Exercise of stock options and employee stock purchase plan | 4 | 2,511 |  | 2,515
Ending Balance at Jun. 30, 2019 | 393 | 304,819 | (167,252) | 137,960
Beginning Balance at Mar. 31, 2019 | 391 | 300,582 | (160,229) | 140,744
Increase (Decrease) in Stockholders' Equity |  |  |  |
Net Loss |  |  | (7,023) | (7,023)
Stock-based compensation |  | 2,674 |  | 2,674
Exercise of stock options | 2 | 1,563 |  | 1,565
Ending Balance at Jun. 30, 2019 | $ 393 | $ 304,819 | $ (167,252) | $ 137,960

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