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Consolidated Statements of Convertible Preferred Stock and Stockholders' (Deficit) Equity - USD ($) $ in Thousands | Total | Convertible Preferred Stock [Member] | Common Stock [Member] | Additional Paid-in Capital [Member] | Accumulated Other Comprehensive Income [Member] | Accumulated Deficit [Member] | Noncontrolling Interest [Member]
--- | --- | --- | --- | --- | --- | --- | ---
Beginning Balance at Dec. 31, 2013 | $ (150,675) | $ 135,202 | $ 1 | $ 9,482 | $ 0 | $ (160,158) | $ 0
Beginning Balance, Shares at Dec. 31, 2013 |  | 5,155,673 | 1,010,711 |  |  |  |
Convertible preferred stock Series G issued for the acquisition of ImmuMetrix, Inc. | 0 | $ 14,242 | $ 0 | 0 | 0 | 0 | 0
Convertible preferred stock Series G issued for the acquisition of ImmuMetrix, Inc., Shares |  | 888,135 | 0 |  |  |  |
Conversion of convertible preferred stock to common stock upon initial public offering | 149,444 | $ (149,444) | $ 6 | 149,438 | 0 | 0 | 0
Conversion of convertible preferred stock to common stock upon initial public offering, Shares |  | (6,043,808) | 6,048,220 |  |  |  |
Conversion of subordinated convertible note to common stock upon initial public offering | 5,108 | $ 0 | $ 1 | 5,107 | 0 | 0 | 0
Conversion of subordinated convertible note to common stock upon initial public offering, Shares |  | 0 | 510,777 |  |  |  |
Conversion of convertible preferred stock warrants to common stock warrants upon initial public offering | 539 | $ 0 | $ 0 | 539 | 0 | 0 | 0
Issuance of common stock upon initial public offering, net of offering costs | 35,511 | $ 0 | $ 4 | 35,507 | 0 | 0 | 0
Issuance of common stock upon initial public offering, net of offering costs, Shares |  | 0 | 4,220,000 |  |  |  |
Issuance of common stock for Board of Director services | 34 | $ 0 | $ 0 | 34 | 0 | 0 | 0
Issuance of common stock for Board of Director services, Shares |  | 0 | 4,899 |  |  |  |
Issuance of common stock for cash upon exercise of stock options | $ 19 | $ 0 | $ 0 | 19 | 0 | 0 | 0
Issuance of common stock for cash upon exercise of stock options, Shares | 9,363 | 0 | 9,363 |  |  |  |
Employee and non-employee share-based compensation expense | $ 535 | $ 0 | $ 0 | 535 | 0 | 0 | 0
Components of other comprehensive loss: |  |  |  |  |  |  |
Foreign currency translation adjustment | 0 |  |  |  |  |  |
Net (loss) income | 781 | 0 | 0 | 0 | 0 | 781 | 0
Total comprehensive loss | 781 |  |  |  |  |  |
Ending Balance at Dec. 31, 2014 | 41,296 | $ 0 | $ 12 | 200,661 | 0 | (159,377) | 0
Ending Balance, Shares at Dec. 31, 2014 |  | 0 | 11,803,970 |  |  |  |
Issuance of common stock for Board of Director services | 223 | $ 0 | $ 0 | 223 | 0 | 0 | 0
Issuance of common stock for Board of Director services, Shares |  | 0 | 38,121 |  |  |  |
Issuance of common stock for cash upon exercise of stock options | $ 46 | $ 0 | $ 0 | 46 | 0 | 0 | 0
Issuance of common stock for cash upon exercise of stock options, Shares | 23,576 | 0 | 23,576 |  |  |  |
Issuance of common stock under equity incentive plans | $ 203 | $ 0 | $ 0 | 203 | 0 | 0 | 0
Issuance of common stock under equity incentive plans, Shares |  | 0 | 36,696 |  |  |  |
Employee and non-employee share-based compensation expense | 1,343 | $ 0 | $ 0 | 1,343 | 0 | 0 | 0
Issuance of warrants to purchase common stock in exchange for debt financing | 90 | 0 | 0 | 90 | 0 | 0 | 0
Components of other comprehensive loss: |  |  |  |  |  |  |
Foreign currency translation adjustment | 0 |  |  |  |  |  |
Net (loss) income | (13,707) | 0 | 0 | 0 | 0 | (13,707) | 0
Total comprehensive loss | (13,707) |  |  |  |  |  |
Ending Balance at Dec. 31, 2015 | 29,494 | $ 0 | $ 12 | 202,566 | 0 | (173,084) | 0
Ending Balance, Shares at Dec. 31, 2015 |  | 0 | 11,902,363 |  |  |  |
Issuance of common stock in connection with business acquisition | 7,205 | $ 0 | $ 1 | 7,204 | 0 | 0 | 0
Issuance of common stock in connection with business acquisition, Shares |  | 0 | 1,375,029 |  |  |  |
Issuance of preferred stock through private placement and subsequent financing | 13,064 | $ 5 | $ 0 | 13,064 | 0 | 0 | 0
Issuance of preferred stock through private placement and subsequent financing, Shares |  | 4,630,145 |  |  |  |  |
Conversion of convertible private placement and subsequent financing preferred stock to common stock | 5 | $ (5) | $ 5 | 0 | 0 | 0 | 0
Conversion of convertible private placement and subsequent financing preferred stock to common stock, Shares |  | (4,630,145) | 4,630,145 |  |  |  |
Issuance of common stock through private placement and subsequent financing | 2,596 | $ 0 | $ 1 | 2,595 | 0 | 0 | 0
Issuance of common stock through private placement and subsequent financing, Shares |  |  | 926,029 |  |  |  |
Issuance of common stock upon initial public offering, net of offering costs | 7,925 | $ 0 | $ 2 | 7,923 | 0 | 0 | 0
Issuance of common stock upon initial public offering, net of offering costs, Shares |  | 0 | 2,283,392 |  |  |  |
Issuance of common stock for Board of Director services | 304 | $ 0 | $ 0 | 304 | 0 | 0 | 0
Issuance of common stock for Board of Director services, Shares |  | 0 | 61,921 |  |  |  |
Issuance of common stock for cash upon exercise of stock options | $ 19 | $ 0 | $ 0 | 19 | 0 | 0 | 0
Issuance of common stock for cash upon exercise of stock options, Shares | 5,688 | 0 | 5,688 |  |  |  |
Issuance of common stock under equity incentive plans | $ 304 | $ 0 | $ 0 | 304 | 0 | 0 | 0
Issuance of common stock under equity incentive plans, Shares |  | 0 | 93,806 |  |  |  |
Employee and non-employee share-based compensation expense | 1,694 | $ 0 | $ 0 | 1,694 | 0 | 0 | 0
Noncontrolling interest upon acquisition | 634 | 0 | 0 | 0 | 0 | 0 | 634
Components of other comprehensive loss: |  |  |  |  |  |  |
Foreign currency translation adjustment | (3,727) | 0 | 0 | 0 | (3,659) | 0 | (68)
Net (loss) income | (39,756) | 0 | 0 | 0 | 0 | (39,469) | (287)
Total comprehensive loss | (43,483) | 0 | 0 | 0 | 0 | 0 | 0
Ending Balance at Dec. 31, 2016 | $ 19,761 | $ 0 | $ 21 | $ 235,673 | $ (3,659) | $ (212,553) | $ 279
Ending Balance, Shares at Dec. 31, 2016 |  | 0 | 21,278,373 |  |  |  |

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