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Consolidated Statements of Convertible Preferred Stock and Stockholders' (Deficit) Equity - USD ($)
$ in Thousands
Total
Convertible Preferred Stock [Member]
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Other Comprehensive Income [Member]
Accumulated Deficit [Member]
Noncontrolling Interest [Member]
Beginning Balance at Dec. 31, 2013 $ (150,675) $ 135,202 $ 1 $ 9,482 $ 0 $ (160,158) $ 0
Beginning Balance, Shares at Dec. 31, 2013   5,155,673 1,010,711        
Convertible preferred stock Series G issued for the acquisition of ImmuMetrix, Inc. 0 $ 14,242 $ 0 0 0 0 0
Convertible preferred stock Series G issued for the acquisition of ImmuMetrix, Inc., Shares   888,135 0        
Conversion of convertible preferred stock to common stock upon initial public offering 149,444 $ (149,444) $ 6 149,438 0 0 0
Conversion of convertible preferred stock to common stock upon initial public offering, Shares   (6,043,808) 6,048,220        
Conversion of subordinated convertible note to common stock upon initial public offering 5,108 $ 0 $ 1 5,107 0 0 0
Conversion of subordinated convertible note to common stock upon initial public offering, Shares   0 510,777        
Conversion of convertible preferred stock warrants to common stock warrants upon initial public offering 539 $ 0 $ 0 539 0 0 0
Issuance of common stock upon initial public offering, net of offering costs 35,511 $ 0 $ 4 35,507 0 0 0
Issuance of common stock upon initial public offering, net of offering costs, Shares   0 4,220,000        
Issuance of common stock for Board of Director services 34 $ 0 $ 0 34 0 0 0
Issuance of common stock for Board of Director services, Shares   0 4,899        
Issuance of common stock for cash upon exercise of stock options $ 19 $ 0 $ 0 19 0 0 0
Issuance of common stock for cash upon exercise of stock options, Shares 9,363 0 9,363        
Employee and non-employee share-based compensation expense $ 535 $ 0 $ 0 535 0 0 0
Components of other comprehensive loss:              
Foreign currency translation adjustment 0            
Net (loss) income 781 0 0 0 0 781 0
Total comprehensive loss 781            
Ending Balance at Dec. 31, 2014 41,296 $ 0 $ 12 200,661 0 (159,377) 0
Ending Balance, Shares at Dec. 31, 2014   0 11,803,970        
Issuance of common stock for Board of Director services 223 $ 0 $ 0 223 0 0 0
Issuance of common stock for Board of Director services, Shares   0 38,121        
Issuance of common stock for cash upon exercise of stock options $ 46 $ 0 $ 0 46 0 0 0
Issuance of common stock for cash upon exercise of stock options, Shares 23,576 0 23,576        
Issuance of common stock under equity incentive plans $ 203 $ 0 $ 0 203 0 0 0
Issuance of common stock under equity incentive plans, Shares   0 36,696        
Employee and non-employee share-based compensation expense 1,343 $ 0 $ 0 1,343 0 0 0
Issuance of warrants to purchase common stock in exchange for debt financing 90 0 0 90 0 0 0
Components of other comprehensive loss:              
Foreign currency translation adjustment 0            
Net (loss) income (13,707) 0 0 0 0 (13,707) 0
Total comprehensive loss (13,707)            
Ending Balance at Dec. 31, 2015 29,494 $ 0 $ 12 202,566 0 (173,084) 0
Ending Balance, Shares at Dec. 31, 2015   0 11,902,363        
Issuance of common stock in connection with business acquisition 7,205 $ 0 $ 1 7,204 0 0 0
Issuance of common stock in connection with business acquisition, Shares   0 1,375,029        
Issuance of preferred stock through private placement and subsequent financing 13,064 $ 5 $ 0 13,064 0 0 0
Issuance of preferred stock through private placement and subsequent financing, Shares   4,630,145          
Conversion of convertible private placement and subsequent financing preferred stock to common stock 5 $ (5) $ 5 0 0 0 0
Conversion of convertible private placement and subsequent financing preferred stock to common stock, Shares   (4,630,145) 4,630,145        
Issuance of common stock through private placement and subsequent financing 2,596 $ 0 $ 1 2,595 0 0 0
Issuance of common stock through private placement and subsequent financing, Shares     926,029        
Issuance of common stock upon initial public offering, net of offering costs 7,925 $ 0 $ 2 7,923 0 0 0
Issuance of common stock upon initial public offering, net of offering costs, Shares   0 2,283,392        
Issuance of common stock for Board of Director services 304 $ 0 $ 0 304 0 0 0
Issuance of common stock for Board of Director services, Shares   0 61,921        
Issuance of common stock for cash upon exercise of stock options $ 19 $ 0 $ 0 19 0 0 0
Issuance of common stock for cash upon exercise of stock options, Shares 5,688 0 5,688        
Issuance of common stock under equity incentive plans $ 304 $ 0 $ 0 304 0 0 0
Issuance of common stock under equity incentive plans, Shares   0 93,806        
Employee and non-employee share-based compensation expense 1,694 $ 0 $ 0 1,694 0 0 0
Noncontrolling interest upon acquisition 634 0 0 0 0 0 634
Components of other comprehensive loss:              
Foreign currency translation adjustment (3,727) 0 0 0 (3,659) 0 (68)
Net (loss) income (39,756) 0 0 0 0 (39,469) (287)
Total comprehensive loss (43,483) 0 0 0 0 0 0
Ending Balance at Dec. 31, 2016 $ 19,761 $ 0 $ 21 $ 235,673 $ (3,659) $ (212,553) $ 279
Ending Balance, Shares at Dec. 31, 2016   0 21,278,373