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Balance Sheet Components - Components of Property and Equipment (Detail) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Property, Plant and Equipment [Line Items]
Total property and equipment	$ 17,086	$ 14,298
Less: Accumulated depreciation and amortization	(14,155)	(11,873)
Property and equipment, net	2,931	2,425
Laboratory equipment [Member]
Property, Plant and Equipment [Line Items]
Total property and equipment	5,065	5,022
Leasehold improvements [Member]
Property, Plant and Equipment [Line Items]
Total property and equipment	5,111	4,326
Furniture and Fixtures [Member]
Property, Plant and Equipment [Line Items]
Total property and equipment	825	825
Computer and office equipment [Member]
Property, Plant and Equipment [Line Items]
Total property and equipment	4,661	4,125
Machinery and Equipment [Member]
Property, Plant and Equipment [Line Items]
Total property and equipment	$ 1,424	$ 0

X

- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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- Definition

Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

+ References

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+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
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-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(13))
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-Publisher FASB
-Name Accounting Standards Codification
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