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Stock Incentive Plans - Summary of Option, Unvested RSU Activity under 2014 Equity Incentive Plan and 2016 Inducement Equity Incentive Plan and Related Information (Detail)
 3 Months Ended
Mar. 31, 2021
$ / shares
shares
Shares Available for Grant  
Shares available for grant beginning balance (in shares) 672,968
Additional options authorized (in shares) 1,977,647
Common stock awards for services (in shares) (1,339)
RSUs granted (in shares) (246,379)
Options granted (in shares) (127,925)
Repurchase of common stock under employee incentive plans (in shares) 74,434
RSUs forfeited (in shares) 69,945
Options forfeited (in shares) 66,213
Options expired (in shares) 250
Shares available for grant ending balance (in shares) 2,485,814
Stock Options Outstanding  
Stock options outstanding beginning balance (in shares) 2,670,398
Options granted (in shares) 127,925
Stock option exercised (in shares) (139,579)
Options forfeited (in shares) (66,213)
Options expired (in shares) (250)
Stock options outstanding ending balance (in shares) 2,592,281
Weighted Average Exercise Price  
Weighted average exercise price beginning balance (in dollars per share) | $ / shares $ 21.92
Weighted average exercise price - options granted (in dollars per share) | $ / shares 81.06
Weighted average exercise price - options exercised (in dollars per share) | $ / shares 13.99
Weighted average exercise price - options forfeited (in dollars per share) | $ / shares 25.70
Weighted average exercise price - options expired (in dollars per share) | $ / shares 22.59
Weighted average exercise price ending balance (in dollars per share) | $ / shares $ 25.17
Number of RSU Shares  
RSUs granted (in shares) 246,379
RSUs forfeited (in shares) (69,945)
Restricted Stock Units  
Shares Available for Grant  
RSUs granted (in shares) (246,379)
RSUs forfeited (in shares) 69,945
Number of RSU Shares  
Number of RSU shares beginning balance (in shares) 1,884,866
RSUs granted (in shares) 246,379
RSUs vested (in shares) (207,881)
RSUs forfeited (in shares) (69,945)
Number of RSU shares ending balance (in shares) 1,853,419
Weighted Average Grant Date Fair Value  
Weighted average grant date fair value beginning balance (in dollars per share) | $ / shares $ 28.42
Weighted average grant date fair value - RSUs granted (in dollars per share) | $ / shares 82.62
Weighted average grant date fair value - RSUs vested (in dollars per share) | $ / shares 24.06
Weighted average grant date fair value - RSUs forfeited (in dollars per share) | $ / shares 29.32
Weighted average grant date fair value ending balance (in dollars per share) | $ / shares $ 36.14