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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Operating activities:    
Net loss $ (23,749) $ (19,648)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:    
Stock-based compensation 13,754 10,634
Revaluation of common stock warrant liability to estimated fair value (7) (27)
Depreciation and amortization 3,427 2,619
Asset impairments and write-downs 1,000 0
Amortization of right-of-use assets 1,337 915
Unrealized loss on long-term marketable equity securities 905 507
Revaluation of contingent consideration to estimated fair value 364 64
Amortization of premium on short-term marketable securities, net (773) 139
Changes in operating assets and liabilities:    
Accounts receivable 7,664 (5,591)
Inventory 1,217 (1,060)
Prepaid and other assets 1,515 (567)
Operating leases liabilities, net (1,333) (969)
Accounts payable 2,590 (1,549)
Accrued compensation (4,888) (14,634)
Accrued and other liabilities (2,352) 7,916
Change in deferred taxes 0 (217)
Net cash provided by (used in) operating activities 671 (21,468)
Investing activities:    
Acquisition of business, net of cash acquired (4,562) 0
Acquisition of intangible assets 0 (100)
Purchases of short-term marketable securities (86,310) (148,522)
Maturities of short-term marketable securities 78,972 1,053
Purchase of corporate equity securities (100) 0
Additions of capital expenditures, net (2,771) (8,463)
Net cash used in investing activities (14,771) (156,032)
Financing activities:    
Proceeds from issuance of common stock under employee stock purchase plan 456 999
Taxes paid related to net share settlement of restricted stock units (656) (1,482)
Proceeds from exercise of stock options 2 1,598
Payment of contingent consideration (250) (250)
Repurchase and retirement of common stock (690) 0
Net cash (used in) provided by financing activities (1,138) 865
Effect of exchange rate changes on cash and cash equivalents (25) 45
Net decrease in cash, cash equivalents and restricted cash (15,263) (176,590)
Cash, cash equivalents, and restricted cash at beginning of period 90,443 348,696
Cash, cash equivalents, and restricted cash at end of period $ 75,180 $ 172,106