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Pay vs Performance Disclosure - USD ($)
 2 Months Ended 10 Months Ended 12 Months Ended
Dec. 31, 2023
Dec. 31, 2020
Oct. 31, 2023
Oct. 31, 2020
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Pay vs Performance Disclosure                
Pay vs Performance Disclosure, Table        
Value of Initial
Fixed
$100
Investment Based
On:
Fiscal
Year (a)
Summary
Compensation
Table
(“SCT”) for
Mr.
Johnson
(PEO 1)
(b)(1)
CAP to
Mr.
Johnson
(PEO 1)
(c)(2)
SCT for Dr.
Seeto (PEO 2)
(d)(1)
CAP to
Dr. Seeto
(PEO 2)
(e)(2)
SCT for
Dr. Maag
(PEO 3) (f)(1)
CAP to
Dr. Maag
(PEO 3)
(g)(2)
Average
SCT
for Non-
PEO NEOs
(h)(3)
Average
CAP
to Non-PEO
NEOs
(i)(2)
TSR
(j)(4)
Peer
Group
TSR
(k)(4)
Net
Income
(in
thousands)
(l)
Revenue
(in
thousands)
(m)(5)
2023$3,097,438 $1,923,573 $10,551,753 $6,665,898 - - $4,617,844 $4,412,835 $55.63 $118.87 ($190,284)$280,324 
2022- - $12,786,270 ($648,097)- - $3,784,612 $118,224 $52.90 $113.65 ($76,613)$321,793 
2021- - $7,090,121 ($50,411)- - $2,605,699 $140,603 $210.85 $126.45 ($30,662)$296,397 
2020- $5,618,698 $17,196,016 $6,400,015 $32,731,502 $1,979,508 $7,956,557 $335.88 $126.42 ($18,714)$192,194 
      
Company Selected Measure Name         Revenue      
Named Executive Officers, Footnote         The dollar amounts reported in columns (b), (d), and (f) are the amounts of total compensation reported for Mr. Johnson (our Principal Executive Officer since November 1, 2023), Dr. Seeto (Chief Executive Officer and Principal Executive Officer from November 1, 2020 to November 1, 2023) and Dr. Maag (Chief Executive Officer until November 1, 2020) for each corresponding year in the “Total” column of the Summary Compensation Table. Refer to the “Summary Compensation Table” on page 64 for additional information. The dollar amounts reported in column (h) are the average amounts of total compensation reported for the Non-PEO NEOs for each corresponding year in the “Total” column of the Summary Compensation Table. Refer to our “Summary Compensation Table” on page 64 for additional information. For each of fiscal years in the table, the Non-PEO NEOs were:
2023202220212020
Abhishek JainAbhishek JainAnkur DhingraMichael Bell
Abraham RonaiAlex JohnsonAlex JohnsonSasha King
Abraham RonaiSasha KingMarcel Konrad
Ankur DhingraPeter Maag, Ph. D.
Sasha KingMarcel Konrad
      
Peer Group Issuers, Footnote         TSR is determined based on the value of an initial fixed investment of $100. The TSR peer group consists of the Nasdaq Biotech Index companies. TSR is calculated by dividing (i) the difference between the stock price at the end of each measurement period shown and the beginning of the measurement period by (ii) the stock price at the beginning of the measurement period.      
Adjustment To PEO Compensation, Footnote         The dollar amounts reported in columns (c), (e), (g), and (i) represent the amount of the CAP, as computed in accordance with SEC rules. The CAP does not necessarily represent cash and/or equity value transferred to the applicable NEO without restriction, but rather is a value calculated under applicable SEC rules. These amounts reflect the total amount of compensation for our NEOs reported in the Summary Compensation Table with certain adjustments as described in the table below for the most recent fiscal year. We do not have a defined benefit plan so no adjustment for pension benefits is included. The valuation assumptions and processes used to recalculate fair values did not materially differ from those disclosed at the time of grant.
Fiscal
Year		ExecutivesSCT
(a)		Grant Date
Value of New
Awards
(b)		Year End
Value of
New Awards
(i)		Change in
Value of
Outstanding
Awards
Granted in
Prior Fiscal
Year
(ii)		Change in
Value of
Vested
Awards
Granted in
Prior
Fiscal
Years
(iii)		Fair Value
of Vested
Awards
Granted
and
Vested in
Current
Fiscal
Year
(iv)		Fair
Value at
Start of
Fiscal
Year of
Awards
that
Failed to
Meet
Vesting
Conditions
(v)		Value of
Dividends
Paid on
Equity
Awards
not
Reflected
in Fair
Value (vi)		Total Equity
CAP
(c)=(i)+(ii)+
(iii)+(iv)		CAP
(d)=(a)-
(b)+(c)
2023PEO 1$3,097,438 $2,406,587 $1,347,837 ($55,129)($59,986)- - - $1,232,722 $1,923,573 
PEO 2$10,551,753 $8,536,615 $4,779,452 ($136,652)$7,959 - - - $4,650,760 $6,665,898 
Non-PEO
NEO Avg		$4,617,844 $3,641,387 $3,507,837 ($12,157)($59,302)- - - $3,436,379 $4,412,835 
      
Non-PEO NEO Average Total Compensation Amount         $ 4,617,844 $ 3,784,612 $ 2,605,699 $ 1,979,508
Non-PEO NEO Average Compensation Actually Paid Amount         $ 4,412,835 118,224 140,603 7,956,557
Adjustment to Non-PEO NEO Compensation Footnote         The dollar amounts reported in columns (c), (e), (g), and (i) represent the amount of the CAP, as computed in accordance with SEC rules. The CAP does not necessarily represent cash and/or equity value transferred to the applicable NEO without restriction, but rather is a value calculated under applicable SEC rules. These amounts reflect the total amount of compensation for our NEOs reported in the Summary Compensation Table with certain adjustments as described in the table below for the most recent fiscal year. We do not have a defined benefit plan so no adjustment for pension benefits is included. The valuation assumptions and processes used to recalculate fair values did not materially differ from those disclosed at the time of grant.
Fiscal
Year		ExecutivesSCT
(a)		Grant Date
Value of New
Awards
(b)		Year End
Value of
New Awards
(i)		Change in
Value of
Outstanding
Awards
Granted in
Prior Fiscal
Year
(ii)		Change in
Value of
Vested
Awards
Granted in
Prior
Fiscal
Years
(iii)		Fair Value
of Vested
Awards
Granted
and
Vested in
Current
Fiscal
Year
(iv)		Fair
Value at
Start of
Fiscal
Year of
Awards
that
Failed to
Meet
Vesting
Conditions
(v)		Value of
Dividends
Paid on
Equity
Awards
not
Reflected
in Fair
Value (vi)		Total Equity
CAP
(c)=(i)+(ii)+
(iii)+(iv)		CAP
(d)=(a)-
(b)+(c)
2023PEO 1$3,097,438 $2,406,587 $1,347,837 ($55,129)($59,986)- - - $1,232,722 $1,923,573 
PEO 2$10,551,753 $8,536,615 $4,779,452 ($136,652)$7,959 - - - $4,650,760 $6,665,898 
Non-PEO
NEO Avg		$4,617,844 $3,641,387 $3,507,837 ($12,157)($59,302)- - - $3,436,379 $4,412,835 
      
Equity Valuation Assumption Difference, Footnote         The recalculated value of equity awards for each applicable year includes the addition (or subtraction, as applicable) of the following:
(i)the year-end fair value of any equity awards granted in the applicable year that are outstanding and unvested as of the end of the applicable year;
(ii)the amount of change as of the end of the applicable year (from the end of the prior fiscal year) in fair value of any awards granted in prior years that are outstanding and unvested as of the end of the applicable year;
(iii)for awards that vest in the applicable year, the change in the fair value as of the vesting date from the beginning of the applicable year;
(iv)for awards that failed to meet vesting conditions in the applicable year, the fair value from the end of prior fiscal year.
(v)for awards that failed to meet vesting conditions in the applicable year, the fair value from the end of prior fiscal year;
(vi)value of dividend not otherwise captured in the calculation of each Fair Value used to calculate CAP
      
Compensation Actually Paid vs. Total Shareholder Return        
5272
      
Compensation Actually Paid vs. Net Income        
5282
      
Compensation Actually Paid vs. Company Selected Measure        
5292
      
Total Shareholder Return Vs Peer Group        
5272
      
Tabular List, Table        
2023 Most Important Performance Measures
The Compensation and Human Capital Committee uses a mix of performance measures throughout our annual and long-term incentive programs to align executive pay with Company performance. As required by SEC rules, the performance measures identified as the most important for all of our NEOs’ 2023 compensation decisions are listed in the table to the right. The measures in this table are not ranked.
Most Important Performance Measures
Revenue
Adjusted EBITDA
Pipeline
      
Total Shareholder Return Amount         $ 55.63 52.90 210.85 335.88
Peer Group Total Shareholder Return Amount         118.87 113.65 126.45 126.42
Net Income (Loss)         $ (190,284,000) $ (76,613,000) $ (30,662,000) $ (18,714,000)
Company Selected Measure Amount         280,324,000 321,793,000 296,397,000 192,194,000
PEO Name Mr. Johnson Dr. Seeto Dr. Seeto Dr. Maag   Dr. Seeto Dr. Seeto  
Additional 402(v) Disclosure         The dollar amounts reported in the Summary Compensation Table for the applicable year.
(b)The grant date fair value of equity awards represents the total of the amounts reported in the “Stock Awards” and “Option Awards” columns of the Summary Compensation Table for the applicable year.
The CAP does not necessarily represent cash and/or equity value transferred to the applicable NEO without restriction, but rather is a value calculated under applicable SEC rules.We determined Revenue to be the most important financial performance measure used to link Company performance to the CAP to our PEOs and Non-PEO NEOs in 2023, consistent with the Total Sales targets used for our short-term incentives (annual bonuses) and long-term incentives (PRSUs). See page 53 of our CD&A for additional information. 		     
Measure:: 1                
Pay vs Performance Disclosure                
Name         Revenue      
Measure:: 2                
Pay vs Performance Disclosure                
Name         Adjusted EBITDA      
Measure:: 3                
Pay vs Performance Disclosure                
Name         Pipeline      
Mr. Johnson [Member]                
Pay vs Performance Disclosure                
PEO Total Compensation Amount $ 3,097,438       $ 3,097,438      
PEO Actually Paid Compensation Amount $ 1,923,573       1,923,573      
Dr. Seeto [Member]                
Pay vs Performance Disclosure                
PEO Total Compensation Amount     $ 10,551,753   10,551,753 $ 12,786,270 $ 7,090,121 $ 5,618,698
PEO Actually Paid Compensation Amount     $ 6,665,898   6,665,898 $ (648,097) $ (50,411) 17,196,016
Dr. Maag [Member]                
Pay vs Performance Disclosure                
PEO Total Compensation Amount               6,400,015
PEO Actually Paid Compensation Amount               $ 32,731,502
PEO | Mr. Johnson [Member] | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         2,406,587      
PEO | Mr. Johnson [Member] | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         1,347,837      
PEO | Mr. Johnson [Member] | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         (55,129)      
PEO | Mr. Johnson [Member] | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         0      
PEO | Mr. Johnson [Member] | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         (59,986)      
PEO | Mr. Johnson [Member] | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         0      
PEO | Mr. Johnson [Member] | Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         0      
PEO | Mr. Johnson [Member] | Total Equity Compensation Actually Paid Adjustment [Member]                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         1,232,722      
PEO | Dr. Seeto [Member] | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         8,536,615      
PEO | Dr. Seeto [Member] | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         4,779,452      
PEO | Dr. Seeto [Member] | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         (136,652)      
PEO | Dr. Seeto [Member] | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         0      
PEO | Dr. Seeto [Member] | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         7,959      
PEO | Dr. Seeto [Member] | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         0      
PEO | Dr. Seeto [Member] | Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         0      
PEO | Dr. Seeto [Member] | Total Equity Compensation Actually Paid Adjustment [Member]                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         4,650,760      
Non-PEO NEO | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         3,641,387      
Non-PEO NEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         3,507,837      
Non-PEO NEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         (12,157)      
Non-PEO NEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         0      
Non-PEO NEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         (59,302)      
Non-PEO NEO | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         0      
Non-PEO NEO | Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         0      
Non-PEO NEO | Total Equity Compensation Actually Paid Adjustment [Member]                
Pay vs Performance Disclosure                
Adjustment to Compensation, Amount         $ 3,436,379