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Stock Incentive Plans (Tables) | 3 Months Ended
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Mar. 31, 2025
Share-Based Payment Arrangement [Abstract] |
Summary of Options, RSUs Activity under 2014 Equity Incentive Plan and 2016 Inducement Plan and Related Information | The following table summarizes option, RSU, and PSU activity under the Company’s 2014 Equity Incentive Plan, 2016 Inducement Equity Incentive Plan and 2019 Inducement Equity Incentive Plan, 2024 Equity Incentive Plan, and related information:
| Shares Available for Grant |  | Stock Options Outstanding |  | Weighted- Average Exercise Price |  | RSU/PSU Outstanding |  | Weighted- Average Grant Date Fair Value
Balance—December 31, 2024 | 4,559,101 |  |  | 3,409,912 |  |  | $ | 22.63 |  |  | 4,842,670 |  |  | $ | 15.38 |
Shares expired | (1,398,171) |  |  | — |  |  | — |  |  | — |  |  | — |
Common stock awards for services | (856) |  |  | — |  |  | — |  |  | — |  |  | — |
RSUs granted | (1,013,286) |  |  | — |  |  | — |  |  | 1,013,286 |  |  | 19.62 |
RSUs vested | — |  |  | — |  |  | — |  |  | (367,450) |  |  | 16.24 |
PSUs granted | (473,754) |  |  | — |  |  | — |  |  | 236,877 |  |  | 19.61 |
PSUs vested | — |  |  | — |  |  | — |  |  | (256,711) |  |  | 15.74 |
Options exercised | — |  |  | (141,050) |  |  | 21.61 |  |  | — |  |  | — |
RSUs forfeited | 10,500 |  |  | — |  |  | — |  |  | (376,425) |  |  | 13.28 |
PSUs forfeited | — |  |  | — |  |  | — |  |  | (34,937) |  |  | 18.50 |
Options forfeited | — |  |  | (72,359) |  |  | 23.83 |  |  | — |  |  | — |
Options expired | — |  |  | (252,065) |  |  | 41.48 |  |  | — |  |  | — |
Balance—March 31, 2025 | 1,683,534 |  |  | 2,944,438 |  |  | $ | 21.03 |  |  | 5,057,310 |  |  | $ | 16.47 |
Summary of Options Outstanding and Exercisable Vested or Expected to Vest | Options outstanding that have vested and are expected to vest at March 31, 2025 are as follows:
| Number of Options Issued (In thousands) |  | Weighted-Average Exercise Price |  | Weighted-Average Remaining Contractual Life (Years) |  | Aggregate Intrinsic Value (In thousands)
Vested | 1,777 |  |  | $ | 24.83 |  |  | 5.60 |  | $ | 4,226 |
Expected to vest | 1,068 |  |  | 15.11 |  |  | 8.76 |  | 6,337 |
Total | 2,845 |  |  |  |  |  |  | $ | 10,563 |
Summary of Weighted-Average Assumptions Used to Estimate Fair Values of Share-Based Awards | The estimated fair values of employee stock options and ESPP shares were estimated using the Black-Scholes option pricing model based on the following weighted average assumptions:
|  | Three Months Ended March 31, |  |
|  | 2025 |  | 2024 |  |  |  |
Employee stock options |  |  |  |  |  |  |  |
Expected term (in years) |  | N/A |  | N/A |  |  |  |
Expected volatility |  | N/A |  | N/A |  |  |  |
Risk-free interest rate |  | N/A |  | N/A |  |  |  |
Expected dividend yield |  | N/A |  | N/A |  |  |  |
Employee stock purchase plan |  |  |  |  |  |  |  |
Expected term (in years) |  | 0.5 |  | 0.5 |  |  |  |
Expected volatility |  | 69.60% |  | 75.91% |  |  |  |
Risk-free interest rate |  | 4.23% |  | 5.38% |  |  |  |
Expected dividend yield |  | —% |  | —% |  |  |  |
Summary of Expense Relating to Employee and Nonemployee Stock-Based Payment Awards from Stock Options and RSUs | The following table summarizes stock-based compensation expense relating to employee and non-employee stock-based awards for the three months ended March 31, 2025 and 2024, included in the condensed consolidated statements of operations as follows (in thousands):
| Three Months Ended March 31, |  |
| 2025 |  | 2024 |  |  |  |
Cost of testing services | $ | 363 |  |  | $ | 457 |  |  |  |  |
Cost of product | 231 |  |  | 317 |  |  |  |  |
Cost of patient and digital solutions | 220 |  |  | 372 |  |  |  |  |
Research and development | 1,359 |  |  | 1,760 |  |  |  |  |
Sales and marketing | 2,584 |  |  | 3,044 |  |  |  |  |
General and administrative | 4,174 |  |  | 10,623 |  |  |  |  |
Total | $ | 8,931 |  |  | $ | 16,573 |  |  |  |  |

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- Definition Tabular disclosure of number, weighted-average exercise price or conversion ratio, aggregate intrinsic value, and weighted-average remaining contractual term for outstanding options that are fully vested and expected to vest. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (e)(1) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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