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Stock Incentive Plans (Tables)
 3 Months Ended
Mar. 31, 2025
Share-Based Payment Arrangement [Abstract]  
Summary of Options, RSUs Activity under 2014 Equity Incentive Plan and 2016 Inducement Plan and Related Information
The following table summarizes option, RSU, and PSU activity under the Company’s 2014 Equity Incentive Plan, 2016 Inducement Equity Incentive Plan and 2019 Inducement Equity Incentive Plan, 2024 Equity Incentive Plan, and related information:
Shares
Available
for Grant		Stock
Options
Outstanding		Weighted-
Average
Exercise
Price

RSU/PSU Outstanding
Weighted-
Average
Grant Date
Fair Value
Balance—December 31, 20244,559,101 3,409,912 $22.63 4,842,670 $15.38 
Shares expired
(1,398,171)— — — — 
Common stock awards for services(856)— — — — 
RSUs granted(1,013,286)— — 1,013,286 19.62 
RSUs vested— — — (367,450)16.24 
PSUs granted
(473,754)— — 236,877 19.61 
PSUs vested
— — — (256,711)15.74 
Options exercised— (141,050)21.61 — — 
RSUs forfeited10,500 — — (376,425)13.28 
PSUs forfeited
— — — (34,937)18.50 
Options forfeited— (72,359)23.83 — — 
Options expired— (252,065)41.48 — — 
Balance—March 31, 20251,683,534 2,944,438 $21.03 5,057,310 $16.47 
Summary of Options Outstanding and Exercisable Vested or Expected to Vest
Options outstanding that have vested and are expected to vest at March 31, 2025 are as follows:
Number of Options Issued
(In thousands)
Weighted-Average
Exercise Price		Weighted-Average Remaining Contractual Life (Years)Aggregate Intrinsic Value
(In thousands)
Vested1,777 $24.83 5.60$4,226 
Expected to vest1,068 15.11 8.766,337 
Total2,845 $10,563 
Summary of Weighted-Average Assumptions Used to Estimate Fair Values of Share-Based Awards
The estimated fair values of employee stock options and ESPP shares were estimated using the Black-Scholes option pricing model based on the following weighted average assumptions:
Three Months Ended March 31,
20252024
Employee stock options
Expected term (in years)N/AN/A
Expected volatilityN/AN/A
Risk-free interest rateN/AN/A
Expected dividend yieldN/AN/A
Employee stock purchase plan
Expected term (in years)0.50.5
Expected volatility69.60%75.91%
Risk-free interest rate4.23%5.38%
Expected dividend yield—%—%
Summary of Expense Relating to Employee and Nonemployee Stock-Based Payment Awards from Stock Options and RSUs
The following table summarizes stock-based compensation expense relating to employee and non-employee stock-based awards for the three months ended March 31, 2025 and 2024, included in the condensed consolidated statements of operations as follows (in thousands):
Three Months Ended March 31,
20252024
Cost of testing services$363 $457 
Cost of product231 317 
Cost of patient and digital solutions220 372 
Research and development1,359 1,760 
Sales and marketing2,584 3,044 
General and administrative4,174 10,623 
Total$8,931 $16,573