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Stock Incentive Plans - Summary of Option, Unvested RSU Activity under 2014 Equity Incentive Plan and 2016 Inducement Equity Incentive Plan and Related Information (Details)
 9 Months Ended
Sep. 30, 2025
$ / shares
shares
Dec. 31, 2024
$ / shares
Number of Shares    
Stock options outstanding beginning balance (in shares) 3,409,912  
Exercised (in shares) (270,747)  
Forfeited (in shares) (89,180)  
Expired (in shares) (394,660)  
Stock options outstanding ending balance (in shares) 2,655,325  
Stock options exercisable (in shares) 1,911,733  
Weighted- Average Exercise Price    
Weighted average exercise price - options (in dollars per share) | $ / shares $ 20.67 $ 22.63
Weighted average exercise price - exercised (in dollars per share) | $ / shares 15.92  
Weighted average exercise price - forfeited (in dollars per share) | $ / shares 24.46  
Weighted average exercise price - expired (in dollars per share) | $ / shares 39.39  
Weighted average exercise price ending balance (in dollars per share) | $ / shares 20.67  
Weighted average exercise price, stock options exercisable (in dollars per share) | $ / shares $ 22.77  
RSU and PSUs    
RSUs/ PSUs outstanding    
Number of RSU shares beginning balance (in shares) 4,842,670  
Number of RSU shares ending balance (in shares) 3,999,915  
Weighted- Average Grant Date Fair Value    
Weighted average grant date fair value beginning balance (in dollars per share) | $ / shares $ 15.38  
Weighted average grant date fair value ending balance (in dollars per share) | $ / shares $ 15.54  
Restricted Stock Units    
RSUs/ PSUs outstanding    
RSUs granted (in shares) 1,542,206  
RSUs vested (in shares) (1,520,059)  
RSUs forfeited (in shares) (828,277)  
Weighted- Average Grant Date Fair Value    
Weighted average grant date fair value - RSUs granted (in dollars per share) | $ / shares $ 18.90  
Weighted average grant date fair value - RSUs vested (in dollars per share) | $ / shares 15.92  
Weighted average grant date fair value - RSUs forfeited (in dollars per share) | $ / shares $ 14.28  
PSUs    
RSUs/ PSUs outstanding    
Number of RSU shares beginning balance (in shares) 335,583  
RSUs granted (in shares) 270,405  
RSUs vested (in shares) (250,863)  
RSUs forfeited (in shares) (56,167)  
Number of RSU shares ending balance (in shares) 221,413  
Weighted- Average Grant Date Fair Value    
Weighted average grant date fair value - RSUs granted (in dollars per share) | $ / shares $ 18.99  
Weighted average grant date fair value - RSUs vested (in dollars per share) | $ / shares 15.14  
Weighted average grant date fair value - RSUs forfeited (in dollars per share) | $ / shares $ 25.41