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Stock Based Compensation (Tables) | 12 Months Ended
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Dec. 31, 2025
Share-Based Payment Arrangement [Abstract] |
Summary of Stock-based Compensation | The following table summarizes stock-based compensation expense by financial statement line item in the Company’s consolidated statements of operations and comprehensive loss for the periods presented (in thousands):
| Year Ended December 31,
| 2025 |  | 2024 |  | 2023
Research and development | $ | 34,210 |  |  | $ | 56,020 |  |  | $ | 145,879 |
General and administrative | 42,463 |  |  | 56,324 |  |  | 84,005 |
Cost of Biosecurity revenue | 2,624 |  |  | — |  |  | — |
Cost of other revenue | 2,249 |  |  | — |  |  | — |
Total | $ | 81,546 |  |  | $ | 112,344 |  |  | $ | 229,884 |
Summary of Stock Option Activity | A summary of time-based stock options activity for the year ended December 31, 2025 is presented below:
| Number of Shares |  | Weighted Average Exercise Price per Share |  | Weighted Average Remaining Contractual Term (in years) |  | Aggregate Intrinsic Value (1)
Outstanding as of December 31, 2024 | 267,520 |  | $ | 25.17 |  |  |  |  |
Granted | 171,875 |  | 9.29 |  |  |  |  |
Exercised | — |  |  | — |  |  |  |  |
Forfeited | (72,828) |  |  | 36.96 |  |  |  |  |
Outstanding as of December 31, 2025 | 366,567 |  | 15.38 |  |  | 8.9 |  | $ | — |
Exercisable as of December 31, 2025 | 136,014 |  | 24.74 |  |  | 8.4 |  | — |
(1)The aggregate intrinsic value is calculated as the difference between the Company's closing stock price on the last trading day of the year and the exercise prices, multiplied by the number of in-the-money stock options.
Schedule of Assumptions Used to Estimate Fair Value of Stock Option Awards Granted | The weighted-average fair value of options granted during the years ended December 31, 2025, 2024, and 2023 was $7.48, $11.35 and $57.20 per share, respectively, and was calculated using the following key assumptions in the Black-Scholes option-pricing model:
| Year Ended December 31,
| 2025 |  | 2024 |  | 2023
Risk-free interest rate | 4.06 | % |  | 4.27 | % |  | 3.94 | %
Expected volatility | 100 | % |  | 97 | % |  | 93 | %
Expected term (in years) | 6.0 |  | 5.7 |  | 5.5
Dividend yield | — | % |  | — | % |  | — | %
Summary of RSU and RSA Activity | A summary of RSU activity for the year ended December 31, 2025 is presented below:
| Number of Shares |  | Weighted Average Grant Date Fair Value
Nonvested as of December 31, 2024 | 3,327,398 |  | $ | 69.00 |
Granted | 1,176,419 |  | 8.02 |
Vested | (1,797,720) |  | 48.74 |
Forfeited | (1,443,244) |  | 56.71 |
Nonvested as of December 31, 2025 | 1,262,853 |  | 55.07 |
Summary of Activity For Earnout RSA | A summary of activity during the year ended December 31, 2025 for the earnout shares is presented below:
| Number of Shares |  | Weighted Average Grant Date Fair Value
Nonvested as of December 31, 2024 | 552,457 |  | $ | 510.80 |
Vested | (321) |  | 533.60 |
Forfeited | (859) |  | 512.62 |
Nonvested as of December 31, 2025 | 551,277 |  | 510.78 |
Schedule of Nonvested Performance-Based Units Activity | A summary of PSU activity for the year ended December 31, 2025 is presented below:
| Performance Stock Units
| Number of Shares |  | Weighted Average Grant Date Fair Value
Granted | 5,599,647 |  | $ | 8.01 |
Vested | — |  |
Forfeited | (1,192,360) |  | 7.81 |
Nonvested as of December 31, 2025 | 4,407,287 |  | 8.06 |

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- Definition Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (d) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (e) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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