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Income Taxes - Summary of Deferred Taxes Assets and Liabilities (Details) - USD ($)
$ in Thousands
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Deferred tax assets:      
Net operating loss carryforwards $ 459,420 $ 332,482  
Tax credit carryforwards 63,612 61,497  
Capitalized research and development costs 155,755 214,208  
Accrued expenses 201 986  
Deferred revenue 21,765 28,549  
Stock-based compensation 48,809 52,388  
Amortizable intangibles 11,755 10,695  
Lease liabilities 112,072 116,118  
Investments in subsidiaries 59,027 57,534  
Property, plant, and equipment 2,464 0  
Other 1,257 1,232  
Deferred tax assets before valuation allowance 936,137 875,689  
Valuation allowance (840,060) (771,852) $ (711,778)
Deferred tax assets, net of valuation allowance 96,077 103,837  
Deferred tax liabilities:      
Amortizable intangibles (10,119) (11,660)  
Property, plant and equipment 0 (545)  
Lease right-of-use assets (92,052) (98,184)  
Deferred tax liabilities (102,171) (110,389)  
Net deferred taxes $ (6,094) $ (6,552)