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Stock Based Compensation (Tables)

12 Months Ended

Dec. 31, 2025

Share-Based Payment Arrangement [Abstract]

Summary of Stock-based Compensation

The following table summarizes stock-based compensation expense by financial statement line item in the Company’s consolidated statements of operations and comprehensive loss for the periods presented (in thousands):

			Year Ended December 31,
			2025						2024						2023
Research and development			$	34,210					$	56,020					$	145,879
General and administrative			42,463						56,324						84,005
Cost of Biosecurity revenue			2,624						—						—
Cost of other revenue			2,249						—						—
Total			$	81,546					$	112,344					$	229,884

Summary of Stock Option Activity

A summary of time-based stock options activity for the year ended December 31, 2025 is presented below:

			Number of Shares						Weighted Average Exercise Price per Share						Weighted Average Remaining Contractual Term (in years)						Aggregate Intrinsic Value (1)
Outstanding as of December 31, 2024			267,520						$	25.17
Granted			171,875						9.29
Exercised			—						—
Forfeited			(72,828)						36.96
Outstanding as of December 31, 2025			366,567						15.38						8.9						$	—
Exercisable as of December 31, 2025			136,014						24.74						8.4						—

(1)The aggregate intrinsic value is calculated as the difference between the Company's closing stock price on the last trading day of the year and the exercise prices, multiplied by the number of in-the-money stock options.

Schedule of Assumptions Used to Estimate Fair Value of Stock Option Awards Granted

The weighted-average fair value of options granted during the years ended December 31, 2025, 2024, and 2023 was $7.48, $11.35 and $57.20 per share, respectively, and was calculated using the following key assumptions in the Black-Scholes option-pricing model:

			Year Ended December 31,
			2025						2024						2023
Risk-free interest rate			4.06		%				4.27		%				3.94		%
Expected volatility			100		%				97		%				93		%
Expected term (in years)			6.0						5.7						5.5
Dividend yield			—		%				—		%				—		%

Summary of RSU and RSA Activity

A summary of RSU activity for the year ended December 31, 2025 is presented below:

			Number of Shares						Weighted Average Grant Date Fair Value
Nonvested as of December 31, 2024			3,327,398						$	69.00
Granted			1,176,419						8.02
Vested			(1,797,720)						48.74
Forfeited			(1,443,244)						56.71
Nonvested as of December 31, 2025			1,262,853						55.07

Summary of Activity For Earnout RSA

A summary of activity during the year ended December 31, 2025 for the earnout shares is presented below:

			Number of Shares						Weighted Average Grant Date Fair Value
Nonvested as of December 31, 2024			552,457						$	510.80
Vested			(321)						533.60
Forfeited			(859)						512.62
Nonvested as of December 31, 2025			551,277						510.78

Schedule of Nonvested Performance-Based Units Activity

A summary of PSU activity for the year ended December 31, 2025 is presented below:

			Performance Stock Units
			Number of Shares						Weighted Average Grant Date Fair Value
Granted			5,599,647						$	8.01
Vested			—
Forfeited			(1,192,360)						7.81
Nonvested as of December 31, 2025			4,407,287						8.06

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