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Consolidated Statements of Cash Flows - USD ($)
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Cash flows from operating activities:      
Net loss $ (312,763,000) $ (547,029,000) $ (892,869,000)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization 58,990,000 63,020,000 70,507,000
Stock-based compensation 81,546,000 112,344,000 229,884,000
Goodwill impairment 0 47,858,000 0
Restructuring related impairment charges 0 4,823,000 0
Non-cash customer consideration 0 (1,117,000) (1,373,000)
Loss on equity method investments 0 0 2,635,000
Loss on investments 16,411,000 28,827,000 54,827,000
Change in fair value of notes receivable 5,685,000 2,014,000 2,416,000
Change in fair value of warrant liabilities 0 (5,701,000) (5,168,000)
Change in fair value of contingent consideration liability (4,232,000) 3,214,000 9,168,000
Loss on deconsolidation of subsidiaries 0 7,013,000 42,502,000
Impairment of long-lived assets 0 5,796,000 121,404,000
Deferred income tax benefit (1,364,000) (936,000) (801,000)
Loss on disposal of equipment 0 844,000 842,000
Non-cash lease expense 30,082,000 28,095,000 28,313,000
Non-cash in-process research and development 0 19,796,000 9,182,000
Accretion of discount on marketable securities (3,390,000) 0 0
Other non-cash activity 2,064,000 1,224,000 3,194,000
Changes in operating assets and liabilities:      
Accounts receivable ($357, $156 and $816 from related parties) (1,473,000) (4,725,000) 50,068,000
Prepaid expenses and other current assets (5,247,000) 10,085,000 10,473,000
Operating lease right-of-use assets 3,814,000 23,463,000 9,275,000
Other non-current assets 296,000 (1,394,000) 2,570,000
Accounts payable (2,992,000) 4,771,000 (1,183,000)
Accrued expenses and other current liabilities 10,376,000 (40,438,000) 16,899,000
Deferred revenue, current and non-current ($(8,147), $(51,422) and $(17,018) from related parties) (32,393,000) (68,645,000) (35,917,000)
Operating lease liabilities, current and non-current (27,932,000) (14,881,000) (22,800,000)
Other non-current liabilities 11,463,000 2,094,000 452,000
Net cash used in operating activities (171,059,000) (319,585,000) (295,500,000)
Cash flows from investing activities:      
Purchases of marketable debt securities (418,630,000) 0 0
Maturities of marketable debt securities 159,483,000 0 0
Proceeds from sale of marketable debt securities 25,899,000 0 0
Purchases of property and equipment (7,665,000) (62,541,000) (40,801,000)
Deconsolidation of subsidiaries - cash 0 0 (42,980,000)
Business acquisitions, net of cash acquired 0 (5,400,000) 0
Purchases of notes receivable 0 0 (350,000)
Proceeds from sales of marketable equity securities 0 4,519,000 0
Proceeds from sale of equipment 574,000 648,000 4,428,000
Other 50,000 538,000 (990,000)
Net cash used in investing activities (240,289,000) (62,236,000) (80,693,000)
Cash flows from financing activities:      
Proceeds from ATM offering 19,469,000 0 0
Payment of issuance costs related to ATM offering (1,340,000) 0 0
Proceeds from exercise of stock options 0 84,000 93,000
Taxes paid related to net share settlement of equity awards 0 0 (23,000)
Principal payments on finance leases (354,000) (897,000) (1,295,000)
Contingent consideration payment 0 (922,000) (1,411,000)
Payment of equity issuance costs and other 0 (4,000) (580,000)
Net cash provided by (used in) financing activities 17,775,000 (1,739,000) (3,216,000)
Effect of foreign exchange rates on cash and cash equivalents 201,000 (281,000) (588,000)
Net decrease in cash, cash equivalents and restricted cash (393,372,000) (383,841,000) (379,997,000)
Cash and cash equivalents, beginning of year 561,572,000 944,073,000 1,315,792,000
Restricted cash, beginning of year 44,171,000 45,511,000 53,789,000
Cash, cash equivalents and restricted cash, beginning of year 605,743,000 989,584,000 1,369,581,000
Cash and cash equivalents, end of year 167,202,000 561,572,000 944,073,000
Restricted cash, end of year 45,169,000 44,171,000 45,511,000
Cash, cash equivalents and restricted cash, end of year $ 212,371,000 $ 605,743,000 $ 989,584,000