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Kyowa Kirin Collaboration and License Agreement - Additional Information (Detail) - USD ($) |  | 1 Months Ended | 3 Months Ended | 9 Months Ended |
--- | --- | --- | --- | --- | ---
Nov. 20, 2024 | Nov. 30, 2024 | Sep. 30, 2025 | Sep. 30, 2025 | Dec. 31, 2024
Kyowa Kirin Collaboration and License Agreement [Line Items] |  |  |  |  |
Current contract liabilities |  |  | $ 48,750,000 | $ 48,750,000 | $ 24,271,000
Long-term contract liabilities |  |  | 268,854,000 | 268,854,000 | $ 253,906,000
Kyowa Clinical Supply Agreement |  |  |  |  |
Kyowa Kirin Collaboration and License Agreement [Line Items] |  |  |  |  |
Revenue |  |  | 500,000 | 500,000 |
Kyowa License Agreement |  |  |  |  |
Kyowa Kirin Collaboration and License Agreement [Line Items] |  |  |  |  |
Upfront payment received | $ 330,000,000 |  |  |  |
Upfront payment received |  |  |  | 330,000,000 |
Unconstrained milestones |  |  |  | 75,000,000 |
Royalties recognized |  |  | 0 | 0 |
Sales based milestones recognized |  |  | 0 | 0 |
Transaction price allocated to performance obligation |  |  | 405,000,000 | 405,000,000 |
Current contract liabilities |  |  | 48,700,000 | 48,700,000 |
Long-term contract liabilities |  |  | 268,900,000 | 268,900,000 |
Kyowa License Agreement | Maximum |  |  |  |  |
Kyowa Kirin Collaboration and License Agreement [Line Items] |  |  |  |  |
Development regulatory and commercial milestone payments in aggregate | 1,161,000,000 |  |  |  |
Upfront and milestone payments in aggregate | $ 1,491,000,000 |  |  |  |
Kyowa License Agreement | Performance Obligations |  |  |  |  |
Kyowa Kirin Collaboration and License Agreement [Line Items] |  |  |  |  |
Contract liability |  |  | 317,600,000 | 317,600,000 |
Kyowa License Agreement | Development Services for Monotherapy |  |  |  |  |
Kyowa Kirin Collaboration and License Agreement [Line Items] |  |  |  |  |
Revenue |  |  | 7,000,000 | 19,800,000 |
Transaction price allocated to performance obligation |  |  | 57,600,000 | 57,600,000 |
Kyowa License Agreement | Development Services in Combination with Other Therapies |  |  |  |  |
Kyowa Kirin Collaboration and License Agreement [Line Items] |  |  |  |  |
Revenue |  |  | 5,100,000 | 10,400,000 |
Transaction price allocated to performance obligation |  |  | 120,200,000 | 120,200,000 |
Kyowa License Agreement | Commercialization Services |  |  |  |  |
Kyowa Kirin Collaboration and License Agreement [Line Items] |  |  |  |  |
Revenue |  |  | 2,300,000 | 5,300,000 |
Transaction price allocated to performance obligation |  |  | 177,400,000 | 177,400,000 |
Kyowa License Agreement | Cost-share Reimbursements |  |  |  |  |
Kyowa Kirin Collaboration and License Agreement [Line Items] |  |  |  |  |
Revenue |  |  | $ 5,900,000 | $ 14,100,000 |
Kyowa License Agreement | License |  |  |  |  |
Kyowa Kirin Collaboration and License Agreement [Line Items] |  |  |  |  |
Revenue |  | $ 49,800,000 |  |  |

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