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v3.25.3

Condensed Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2025 | Sep. 30, 2024
Operating Activities |  |
Net loss | $ (197,667) | $ (154,766)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Share-based compensation expense | 25,756 | 25,266
Depreciation expense | 629 | 644
Non-cash interest expense | 412 | 383
Amortization of premium and accretion of discounts on short-term investments, net | (7,106) | (10,256)
Changes in operating assets and liabilities: |  |
Contract liabilities | 39,427 |
Accounts payable and accrued expenses | 14,814 | 2,498
Other long-term liabilities | 925 | 523
Receivable from contracts with collaborators | (33,876) |
Prepaid expenses and other current assets | (18,840) | 632
Operating lease right-of-use and other long-term assets | (5,805) | 262
Net cash used in operating activities | (181,331) | (134,814)
Investing Activities |  |
Maturities of short-term investments | 577,628 | 411,930
Purchases of short-term investments | (521,813) | (418,465)
Purchases of property and equipment | (4,317) | (100)
Net cash provided by (used in) investing activities | 51,498 | (6,635)
Financing Activities |  |
Proceeds from issuance of stock under equity plans | 658 | 7,797
Proceeds from issuance of common stock and pre-funded warrants, net of offering costs |  | 145,814
Net cash provided by financing activities | 658 | 153,611
Net increase (decrease) in cash and cash equivalents | (129,175) | 12,162
Cash and cash equivalents at beginning of period | 224,462 | 37,318
Cash and cash equivalents at end of period | 95,287 | $ 49,480
Supplemental disclosure of non-cash investing activities |  |
Unpaid amounts related to purchases of property and equipment | $ 2,027 |

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