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Insider Trading Arrangements | 3 Months Ended
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Sep. 30, 2025 shares
Trading Arrangements, by Individual |
Material Terms of Trading Arrangement | Trading Plans During the three months ended September 30, 2025, certain of our directors and officers adopted, modified or terminated contracts, instructions or written plans for the purchase or sale of our securities as noted below:
|  |  | Trading Arrangement |  |
Name and Position | Action | Date | Rule 10b5-1* | Non-Rule 10b5-1** | Total Shares to be Sold | Expiration Date
Kathleen Ford, Chief Operating Officer | Termination*** | August 28, 2025 | X |  | 74,438, and ESPP net shares to be purchased | September 15, 2025
Kathleen Ford, Chief Operating Officer | Adoption*** | August 29, 2025 | X |  | 79,696, PSUs and RSUs net shares to be received, and ESPP net shares to be purchased | August 31, 2026
Teresa Bair, Chief Legal Officer | Adoption | September 4, 2025 | X |  | 218,021, and ESPP net shares to be purchased | December 5, 2026
Mollie Leoni, M.D., Chief Medical Officer | Adoption | September 9, 2025 | X |  | 99,531, and RSUs net shares to be received | December 31, 2026
Brian Powl, Chief Commercial Officer | Adoption | September 19, 2025 | X |  | 90,116, Options net shares unsold, RSUs net shares to be received, and ESPP net shares to be purchased | December 31, 2026
Faheem Hasnain, Lead Independent Director | Adoption | September 9, 2025 | X |  | 20,000 | June 9, 2027
______________________ * Intended to satisfy the affirmative defense of Rule 10b5-1(c) ** Not intended to satisfy the affirmative defense of Rule 10b5-1(c) *** Represents the modification, as described in Rule 10b5-1(c)(1)(iv) under the Exchange Act, of a written plan adopted on June 10, 2024 that was intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) under the Exchange Act. In addition, our officers (as defined in Rule 16a-1(f) under the Exchange Act) have entered into sell-to-cover arrangements adopted pursuant to Rule 10b5-1 authorizing the pre-arranged sale of shares to satisfy our tax withholding obligations arising exclusively from the vesting of shares of restricted stock. The amount of shares to be sold to satisfy our tax withholding obligations under these arrangements is dependent on future events which cannot be known at this time, including the future trading price of our shares. The expiration date relating to these arrangements is dependent on future events which cannot be known at this time, including the final vesting date of the applicable shares of restricted stock and the officer’s termination of service.
Kathleen Ford |
Trading Arrangements, by Individual |
Name | Kathleen Ford
Title | Chief Operating Officer
Rule 10b5-1 Arrangement Terminated | true
Termination Date | August 28, 2025
Expiration Date | September 15, 2025
Arrangement Duration | 19 days
Aggregate Available | 74,438
Kathleen Ford |
Trading Arrangements, by Individual |
Name | Kathleen Ford
Title | Chief Operating Officer
Rule 10b5-1 Arrangement Adopted | true
Adoption Date | August 29, 2025
Expiration Date | August 31, 2026
Arrangement Duration | 368 days
Aggregate Available | 79,696
Teresa Bair |
Trading Arrangements, by Individual |
Name | Teresa Bair
Title | Chief Legal Officer
Rule 10b5-1 Arrangement Adopted | true
Adoption Date | September 4, 2025
Expiration Date | December 5, 2026
Arrangement Duration | 458 days
Aggregate Available | 218,021
Mollie Leoni |
Trading Arrangements, by Individual |
Name | Mollie Leoni, M.D.
Title | Chief Medical Officer
Rule 10b5-1 Arrangement Adopted | true
Adoption Date | September 9, 2025
Expiration Date | December 31, 2026
Arrangement Duration | 479 days
Aggregate Available | 99,531
Brian Powl |
Trading Arrangements, by Individual |
Name | Brian Powl
Title | Chief Commercial Officer
Rule 10b5-1 Arrangement Adopted | true
Adoption Date | September 19, 2025
Expiration Date | December 31, 2026
Arrangement Duration | 456 days
Aggregate Available | 90,116
Faheem Hasnain |
Trading Arrangements, by Individual |
Name | Faheem Hasnain
Title | Lead Independent Director
Rule 10b5-1 Arrangement Adopted | true
Adoption Date | September 9, 2025
Expiration Date | June 9, 2027
Arrangement Duration | 640 days
Aggregate Available | 20,000

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