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Collaboration Agreements - Additional Information (Details)	1 Months Ended		3 Months Ended			12 Months Ended
	Aug. 31, 2020 USD ($) Program	Oct. 31, 2018 Program	Mar. 31, 2023 USD ($)	Mar. 31, 2022 USD ($)	Sep. 30, 2020 USD ($)	Dec. 31, 2018 USD ($)	Dec. 31, 2022 USD ($)	Sep. 30, 2021 USD ($)	Dec. 31, 2020 USD ($)
2018 Gilead Agreement [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research term		3 years
Number of licensed product | Program		5
Non-refundable upfront payment received			$ 50,000,000.0			$ 50,000,000.0
Amended Gilead Agreement [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research term	7 years
Number of licensed product | Program	15
Non-refundable upfront payment received			$ 125,000,000.0
Milestone payments receivable	$ 410,000,000.0
Temporary equity, par value	125,000,000.0
Revenue recognized, cumulative catch-up adjustment					$ (11,300,000)
Research extension fee								$ 12,000,000.0	$ 12,000,000.0
Amended Gilead Agreement [Member] | Minimum [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Ownership percentage in common stock			10.00%
Amended Gilead Agreement [Member] | Series B-1 Preferred Stock [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Temporary equity, par value	$ 20,000,000.0
Gilead Agreement [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Transaction price allocated to performance obligation			$ 199,000,000.0
Cummulative research extension fee			24,000,000.0
Short-term deferred revenue			34,000,000.0				$ 31,800,000
Long-term deferred revenue			84,100,000				$ 92,100,000
Collaboration Revenue [Member] | Gilead Agreement [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Contract with customer liability, revenue recognized			$ 5,800,000	$ 5,800,000

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- Definition

Amount of increase (decrease) in revenue recognized for cumulative catch-up adjustment from contract modification which (increases) decreases obligation to transfer good or service to customer for which consideration from customer has been received or is due.

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-Section 50
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Amount of revenue recognized that was previously included in balance of obligation to transfer good or service to customer for which consideration from customer has been received or is due.

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