Equity Offering Agreements	3 Months Ended
Dec. 31, 2020
Equity Offering Agreements
Equity Offering Agreements	Note 4 Equity Offering Agreements 2019 Purchase Agreement On June 7, 2019, the Company entered into a $50,000,000 purchase agreement (the “2019 Purchase Agreement”) with Lincoln Park, as amended on July 1, 2020 , pursuant to which the Company had the right to sell and issue to Lincoln Park, and Lincoln Park was obligated to purchase, up to $50,000,000 in value of its shares of common stock from time to time from June 12, 2019, the date a prospectus supplement under which shares of common stock issuable under the 2019 Purchase Agreement was filed with the SEC, until such date as the Company directed Lincoln Park to purchase the $50,000,000 aggregate commitment, or July 1, 2022. In consideration for entering into the 2019 Purchase Agreement, the Company issued to Lincoln Park 324,383 shares of common stock as a commitment fee and agreed to issue up to 162,191 shares pro rata, when and if, Lincoln Park purchased at the Company’s discretion the $50,000,000 aggregate commitment. During the three months ended December 31, 2020, the Company issued to Lincoln Park an aggregate of 3,402,930 (2019 – 4,429,835) shares of common stock under the 2019 Purchase Agreement, including 3,346,288 (2019: 4,394,160) shares of common stock for an aggregate purchase price of $17,461,402 (2019: $10,997,952) and 56,642 (2019: 35,675) commitment shares. At December 31, 2020, an amount of $6,649,794 (September 30, 2020: $24,111,197) remained available under the 2019 Purchase Agreement. Sales Agreement The Company entered into a Controlled Equity Offering Sales Agreement on July 6, 2018, which was amended and restated on May 1, 2020 (the “Sales Agreement”) with Cantor Fitzgerald & Co. and SVB Leerink LLC (together the “Sales Agents”), pursuant to which the Company may offer and sell shares of common stock registered under an effective registration statement from time to time through the Sales Agents (the “Offering”). Upon delivery of a placement notice based on the Company’s instructions and subject to the terms and conditions of the Sales Agreement, the Sales Agents may sell the Shares by methods deemed to be an “at the market offering” offering, in negotiated transactions at market prices prevailing at the time of sale or at prices related to such prevailing market prices, or by any other method permitted by law, including negotiated transactions, subject to the prior written consent of the Company. The Company is not obligated to make any sales of Shares under the Sales Agreement. The Company or Sales Agents may suspend or terminate the offering of Shares upon notice to the other party, subject to certain conditions. The Sales Agents will act as agent on a commercially reasonable efforts basis consistent with their normal trading and sales practices and applicable state and federal law, rules and regulations and the rules of Nasdaq. The Company has agreed to pay the Sales Agents commissions for their services of up to 3.0% of the gross proceeds from the sale of the Shares pursuant to the Sales Agreement. The Company also agreed to provide the Sales Agents with customary indemnification and contribution rights. During the three months ended December 31, 2020, 1,514,829 shares were sold pursuant to the Offering for gross proceeds of $8,782,017 (net proceeds of $8,518,557 after deducting offering expenses). At December 31, 2020, an amount of $33,718,084 (September 30, 2020: $42,500,100) remained registered under the Company’s effective shelf registration statement and available to be offered and sold in the Offering.

Equity Offering Agreements

3 Months Ended

Dec. 31, 2020

Note 4 Equity Offering Agreements

2019 Purchase Agreement

On June 7, 2019, the Company entered into a $50,000,000 purchase agreement (the “2019 Purchase Agreement”) with Lincoln Park, as amended on July 1, 2020 , pursuant to which the Company had the right to sell and issue to Lincoln Park, and Lincoln Park was obligated to purchase, up to $50,000,000 in value of its shares of common stock from time to time from June 12, 2019, the date a prospectus supplement under which shares of common stock issuable under the 2019 Purchase Agreement was filed with the SEC, until such date as the Company directed Lincoln Park to purchase the $50,000,000 aggregate commitment, or July 1, 2022.

In consideration for entering into the 2019 Purchase Agreement, the Company issued to Lincoln Park 324,383 shares of common stock as a commitment fee and agreed to issue up to 162,191 shares pro rata, when and if, Lincoln Park purchased at the Company’s discretion the $50,000,000 aggregate commitment.

During the three months ended December 31, 2020, the Company issued to Lincoln Park an aggregate of 3,402,930 (2019 – 4,429,835) shares of common stock under the 2019 Purchase Agreement, including 3,346,288 (2019: 4,394,160) shares of common stock for an aggregate purchase price of $17,461,402 (2019: $10,997,952) and 56,642 (2019: 35,675) commitment shares. At December 31, 2020, an amount of $6,649,794 (September 30, 2020: $24,111,197) remained available under the 2019 Purchase Agreement.

Sales Agreement

The Company entered into a Controlled Equity Offering Sales Agreement on July 6, 2018, which was amended and restated on May 1, 2020 (the “Sales Agreement”) with Cantor Fitzgerald & Co. and SVB Leerink LLC (together the “Sales Agents”), pursuant to which the Company may offer and sell shares of common stock registered under an effective registration statement from time to time through the Sales Agents (the “Offering”).

Upon delivery of a placement notice based on the Company’s instructions and subject to the terms and conditions of the Sales Agreement, the Sales Agents may sell the Shares by methods deemed to be an “at the market offering” offering, in negotiated transactions at market prices prevailing at the time of sale or at prices related to such prevailing market prices, or by any other method permitted by law, including negotiated transactions, subject to the prior written consent of the Company. The Company is not obligated to make any sales of Shares under the Sales Agreement. The Company or Sales Agents may suspend or terminate the offering of Shares upon notice to the other party, subject to certain conditions. The Sales Agents will act as agent on a commercially reasonable efforts basis consistent with their normal trading and sales practices and applicable state and federal law, rules and regulations and the rules of Nasdaq.

The Company has agreed to pay the Sales Agents commissions for their services of up to 3.0% of the gross proceeds from the sale of the Shares pursuant to the Sales Agreement. The Company also agreed to provide the Sales Agents with customary indemnification and contribution rights. During the three months ended December 31, 2020, 1,514,829 shares were sold pursuant to the Offering for gross proceeds of $8,782,017 (net proceeds of $8,518,557 after deducting offering expenses). At December 31, 2020, an amount of $33,718,084 (September 30, 2020: $42,500,100) remained registered under the Company’s effective shelf registration statement and available to be offered and sold in the Offering.