<SEC-DOCUMENT>0001731122-23-002197.txt : 20231127
<SEC-HEADER>0001731122-23-002197.hdr.sgml : 20231127
<ACCEPTANCE-DATETIME>20231127163041
ACCESSION NUMBER:		0001731122-23-002197
CONFORMED SUBMISSION TYPE:	10-K
PUBLIC DOCUMENT COUNT:		58
CONFORMED PERIOD OF REPORT:	20230930
FILED AS OF DATE:		20231127
DATE AS OF CHANGE:		20231127

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ANAVEX LIFE SCIENCES CORP.
		CENTRAL INDEX KEY:			0001314052
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				980608404
		FISCAL YEAR END:			0930

	FILING VALUES:
		FORM TYPE:		10-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37606
		FILM NUMBER:		231440632

	BUSINESS ADDRESS:	
		STREET 1:		630 5TH AVENUE
		STREET 2:		20TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10111
		BUSINESS PHONE:		844-689-3939

	MAIL ADDRESS:	
		STREET 1:		630 5TH AVENUE
		STREET 2:		20TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10111

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Thrifty Printing Inc.
		DATE OF NAME CHANGE:	20050111
</SEC-HEADER>
<DOCUMENT>
<TYPE>10-K
<SEQUENCE>1
<FILENAME>e5240_10k.htm
<DESCRIPTION>FORM 10-K
<TEXT>
<XBRL>
<?xml version="1.0" encoding="utf-8"?>
<html xmlns="http://www.w3.org/1999/xhtml" xmlns:xs="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:xbrldi="http://xbrl.org/2006/xbrldi" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:iso4217="http://www.xbrl.org/2003/iso4217" xmlns:ix="http://www.xbrl.org/2013/inlineXBRL" xmlns:ixt="http://www.xbrl.org/inlineXBRL/transformation/2015-02-26" xmlns:ixt-sec="http://www.sec.gov/inlineXBRL/transformation/2015-08-31" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:dei="http://xbrl.sec.gov/dei/2023" xmlns:ref="http://www.xbrl.org/2006/ref" xmlns:us-gaap="http://fasb.org/us-gaap/2023" xmlns:us-roles="http://fasb.org/us-roles/2023" xmlns:dtr-types="http://www.xbrl.org/dtr/type/2022-03-31" xmlns:country="http://xbrl.sec.gov/country/2023" xmlns:currency="http://xbrl.sec.gov/currency/2023" xmlns:srt="http://fasb.org/srt/2023" xmlns:avxl="http://anavex.com/20230930">
<head>
     <title></title>
<meta http-equiv="Content-Type" content="text/html" />
</head>
<!-- Field: Set; Name: xdx; ID: xdx_02C_US%2DGAAP%2D2023 -->
<!-- Field: Set; Name: xdx; ID: xdx_03B_avxl_anavex.com_20230930 -->
<!-- Field: Set; Name: xdx; ID: xdx_04E_20221001_20230930 -->
<!-- Field: Set; Name: xdx; ID: xdx_059_edei%2D%2DAmendmentFlag_false -->
<!-- Field: Set; Name: xdx; ID: xdx_053_edei%2D%2DDocumentFiscalYearFocus_2023 -->
<!-- Field: Set; Name: xdx; ID: xdx_05A_edei%2D%2DDocumentFiscalPeriodFocus_FY -->
<!-- Field: Set; Name: xdx; ID: xdx_05A_edei%2D%2DEntityCentralIndexKey_0001314052 -->
<!-- Field: Set; Name: xdx; ID: xdx_06B_USD_1_iso4217%2D%2DUSD -->
<!-- Field: Set; Name: xdx; ID: xdx_062_Shares_2_xbrli%2D%2Dshares -->
<!-- Field: Set; Name: xdx; ID: xdx_06D_USDPShares_3_iso4217%2D%2DUSD_xbrli%2D%2Dshares -->
<!-- Field: Set; Name: xdx; ID: xdx_069_Pure_4_xbrli%2D%2Dpure -->
<body style="font: 10pt Times New Roman, Times, Serif">
<div style="display: none">
<ix:header>
 <ix:hidden>
  <ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:AmendmentFlag">false</ix:nonNumeric>
  <ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:DocumentFiscalYearFocus">2023</ix:nonNumeric>
  <ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:DocumentFiscalPeriodFocus">FY</ix:nonNumeric>
  <ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:EntityCentralIndexKey">0001314052</ix:nonNumeric>
  <ix:nonFraction name="us-gaap:CommitmentsAndContingencies" contextRef="AsOf2023-09-30" id="xdx2ixbrl0084" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:CommitmentsAndContingencies" contextRef="AsOf2022-09-30" id="xdx2ixbrl0085" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:PreferredStockValue" contextRef="AsOf2023-09-30" id="xdx2ixbrl0095" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:PreferredStockValue" contextRef="AsOf2022-09-30" id="xdx2ixbrl0097" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:NonOperatingIncomeFromGrants" contextRef="From2021-10-012022-09-30" id="xdx2ixbrl0156" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:OtherFinancingExpense" contextRef="From2021-10-012022-09-30" id="xdx2ixbrl0168" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:OtherFinancingExpense" contextRef="From2020-10-012021-09-30" id="xdx2ixbrl0169" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:NoncashFinancingRelatedCharges" contextRef="From2021-10-012022-09-30" id="xdx2ixbrl0236" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:NoncashFinancingRelatedCharges" contextRef="From2020-10-012021-09-30" id="xdx2ixbrl0237" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:DeferredGrantIncome" contextRef="From2021-10-012022-09-30" id="xdx2ixbrl0264" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:PaymentsOfStockIssuanceCosts" contextRef="From2022-10-01to2023-09-30" id="xdx2ixbrl0279" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:ProceedsFromWarrantExercises" contextRef="From2022-10-01to2023-09-30" id="xdx2ixbrl0283" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:ProceedsFromWarrantExercises" contextRef="From2021-10-012022-09-30" id="xdx2ixbrl0284" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:StockRepurchasedDuringPeriodValue" contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0324" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:StockRepurchasedDuringPeriodValue" contextRef="From2020-10-012021-09-30" id="xdx2ixbrl0325" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:CommitmentShares" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" id="xdx2ixbrl0329" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:CommitmentShares" contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember" id="xdx2ixbrl0330" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:CommitmentShares" contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0331" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:CommitmentShares" contextRef="From2020-10-012021-09-30" id="xdx2ixbrl0332" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:SharesIssuedUnderSalesAgreement" contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0338" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:LessSalesAgreementShareIssueCosts" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" id="xdx2ixbrl0343" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:LessSalesAgreementShareIssueCosts" contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0345" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:SharesIssuedPursuantToRegisteredDirectOffering" contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0350" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:LessRegisteredDirectOfferingShareIssueCosts" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" id="xdx2ixbrl0355" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:LessRegisteredDirectOfferingShareIssueCosts" contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0357" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:SharesIssuedPursuantToExerciseOfStockOptions" contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0362" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:SharesIssuedPusuantToExerciseOfWarrants" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" id="xdx2ixbrl0367" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:SharesIssuedPusuantToExerciseOfWarrants" contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0369" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" id="xdx2ixbrl0374" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0376" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" id="xdx2ixbrl0379" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember" id="xdx2ixbrl0380" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:SharesIssuedUnderSalesAgreement" contextRef="From2021-10-012022-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0393" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:LessSalesAgreementShareIssueCosts" contextRef="From2021-10-012022-09-30_us-gaap_CommonStockMember" id="xdx2ixbrl0398" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:LessSalesAgreementShareIssueCosts" contextRef="From2021-10-012022-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0400" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:SharesIssuedPursuantToExerciseOfStockOptions" contextRef="From2021-10-012022-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0405" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" contextRef="From2021-10-012022-09-30_us-gaap_CommonStockMember" id="xdx2ixbrl0410" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" contextRef="From2021-10-012022-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0412" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2021-10-012022-09-30_us-gaap_CommonStockMember" id="xdx2ixbrl0415" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2021-10-012022-09-30_us-gaap_AdditionalPaidInCapitalMember" id="xdx2ixbrl0416" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares" contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember" id="xdx2ixbrl0427" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares" contextRef="From2022-10-012023-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0429" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:StockRepurchasedDuringPeriodValue" contextRef="From2022-10-012023-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0436" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:CommitmentShares" contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember" id="xdx2ixbrl0441" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:CommitmentShares" contextRef="From2022-10-012023-09-30_us-gaap_AdditionalPaidInCapitalMember" id="xdx2ixbrl0442" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:CommitmentShares" contextRef="From2022-10-012023-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0443" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:CommitmentShares" contextRef="From2022-10-01to2023-09-30" id="xdx2ixbrl0444" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:SharesIssuedPursuantToExerciseOfStockOptions" contextRef="From2022-10-012023-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0450" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember" id="xdx2ixbrl0455" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" contextRef="From2022-10-012023-09-30_us-gaap_RetainedEarningsMember" id="xdx2ixbrl0457" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember" id="xdx2ixbrl0460" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2022-10-012023-09-30_us-gaap_AdditionalPaidInCapitalMember" id="xdx2ixbrl0461" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" contextRef="AsOf2021-09-30_us-gaap_StockOptionMember" id="xdx2ixbrl0768" unitRef="USDPShares" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:DeferredTaxAssetsResearchAndDevelopmentCapitalization" contextRef="AsOf2022-09-30" id="xdx2ixbrl1029" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:DeferredTaxAssetsResearchAndDevelopmentCapitalization" contextRef="AsOf2021-09-30" id="xdx2ixbrl1030" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:DeferredTaxAssetsNet" contextRef="AsOf2023-09-30" id="xdx2ixbrl1048" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:DeferredTaxAssetsNet" contextRef="AsOf2022-09-30" id="xdx2ixbrl1049" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:DeferredTaxAssetsNet" contextRef="AsOf2021-09-30" id="xdx2ixbrl1050" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:IncomeTaxReconciliationForeignIncomeTaxRateDifferential" contextRef="From2022-10-01to2023-09-30" id="xdx2ixbrl1058" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:EffectiveIncomeTaxRateReconciliationGiltiAmount" contextRef="From2021-10-012022-09-30" id="xdx2ixbrl1067" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:EffectiveIncomeTaxRateReconciliationGiltiAmount" contextRef="From2020-10-012021-09-30" id="xdx2ixbrl1068" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:PermanentDifferencesRelatingToSection162m" contextRef="From2022-10-01to2023-09-30" id="xdx2ixbrl1070" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:PermanentDifferencesRelatingToSection162m" contextRef="From2021-10-012022-09-30" id="xdx2ixbrl1071" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:IncomeTaxReconciliationOtherAdjustments" contextRef="From2021-10-012022-09-30" id="xdx2ixbrl1075" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:AdjustmentToTaxAssetsBasedOnSection382" contextRef="From2022-10-01to2023-09-30" id="xdx2ixbrl1078" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="avxl:AdjustmentToTaxAssetsBasedOnSection382" contextRef="From2021-10-012022-09-30" id="xdx2ixbrl1079" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:IncomeTaxReconciliationChangeInEnactedTaxRate" contextRef="From2022-10-01to2023-09-30" id="xdx2ixbrl1094" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:IncomeTaxReconciliationChangeInEnactedTaxRate" contextRef="From2021-10-012022-09-30" id="xdx2ixbrl1095" unitRef="USD" xs:nil="true"></ix:nonFraction>
  <ix:nonFraction name="us-gaap:TaxesExcludingIncomeAndExciseTaxes" contextRef="From2022-10-01to2023-09-30" id="xdx2ixbrl1098" unitRef="USD" xs:nil="true"></ix:nonFraction>
  </ix:hidden>
 <ix:references>
  <link:schemaRef xlink:href="avxl-20230930.xsd" xlink:type="simple" />
  </ix:references>
 <ix:resources>
    <xbrli:context id="From2022-10-01to2023-09-30">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-03-31">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-03-31</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-11-24">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-11-24</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2022-09-30">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2022-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-10-012022-09-30">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-10-01</xbrli:startDate>
        <xbrli:endDate>2022-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2020-10-012021-09-30">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2020-10-01</xbrli:startDate>
        <xbrli:endDate>2021-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2021-09-30">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2021-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2020-09-30">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2020-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2020-09-30_us-gaap_CommonStockMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2020-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2020-09-30_us-gaap_AdditionalPaidInCapitalMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2020-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2020-09-30_us-gaap_RetainedEarningsMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2020-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2021-09-30_us-gaap_CommonStockMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2021-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2021-09-30_us-gaap_AdditionalPaidInCapitalMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2021-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2021-09-30_us-gaap_RetainedEarningsMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2021-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2022-09-30_us-gaap_CommonStockMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2022-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2022-09-30_us-gaap_AdditionalPaidInCapitalMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2022-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2022-09-30_us-gaap_RetainedEarningsMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2022-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2020-10-012021-09-30_us-gaap_CommonStockMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2020-10-01</xbrli:startDate>
        <xbrli:endDate>2021-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2020-10-01</xbrli:startDate>
        <xbrli:endDate>2021-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2020-10-01</xbrli:startDate>
        <xbrli:endDate>2021-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-10-012022-09-30_us-gaap_CommonStockMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-10-01</xbrli:startDate>
        <xbrli:endDate>2022-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-10-012022-09-30_us-gaap_AdditionalPaidInCapitalMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-10-01</xbrli:startDate>
        <xbrli:endDate>2022-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-10-012022-09-30_us-gaap_RetainedEarningsMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-10-01</xbrli:startDate>
        <xbrli:endDate>2022-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_us-gaap_CommonStockMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_us-gaap_AdditionalPaidInCapitalMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_us-gaap_RetainedEarningsMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_us-gaap_CommonStockMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_us-gaap_AdditionalPaidInCapitalMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_us-gaap_RetainedEarningsMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2020-10-012021-09-30_custom_MichaelJFoxFoundationMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:RelatedPartyTransactionsByRelatedPartyAxis">avxl:MichaelJFoxFoundationMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2020-10-01</xbrli:startDate>
        <xbrli:endDate>2021-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_currency_AUD">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:AUD</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-10-012022-09-30_currency_AUD">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:AUD</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-10-01</xbrli:startDate>
        <xbrli:endDate>2022-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2020-10-012021-09-30_currency_AUD">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:AUD</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2020-10-01</xbrli:startDate>
        <xbrli:endDate>2021-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_currency_AUD">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:AUD</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2022-09-30_currency_AUD">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:AUD</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2022-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-06-212021-06-22_custom_SecuritiesPurchaseAgreementMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:SecuritiesPurchaseAgreementMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-06-21</xbrli:startDate>
        <xbrli:endDate>2021-06-22</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2021-06-22_custom_SecuritiesPurchaseAgreementMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:SecuritiesPurchaseAgreementMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2021-06-22</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_custom_EquityOfferingSalesAgreementMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:EquityOfferingSalesAgreementMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-10-012022-09-30_custom_EquityOfferingSalesAgreementMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:EquityOfferingSalesAgreementMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-10-01</xbrli:startDate>
        <xbrli:endDate>2022-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2020-10-012021-09-30_custom_EquityOfferingSalesAgreementMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:EquityOfferingSalesAgreementMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2020-10-01</xbrli:startDate>
        <xbrli:endDate>2021-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2023-02-022023-02-03_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2023-02-02</xbrli:startDate>
        <xbrli:endDate>2023-02-03</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockIncludingCommitmentSharesMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommonStockIncludingCommitmentSharesMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockIncludingCommitmentSharesMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommonStockIncludingCommitmentSharesMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-10-01</xbrli:startDate>
        <xbrli:endDate>2022-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockExcludingCommitmentSharesMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommonStockExcludingCommitmentSharesMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockExcludingCommitmentSharesMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommonStockExcludingCommitmentSharesMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-10-01</xbrli:startDate>
        <xbrli:endDate>2022-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-10-01</xbrli:startDate>
        <xbrli:endDate>2022-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommitmentSharesMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommitmentSharesMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommitmentSharesMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommitmentSharesMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-10-01</xbrli:startDate>
        <xbrli:endDate>2022-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2023-02-022023-02-03_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2019Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2023-02-02</xbrli:startDate>
        <xbrli:endDate>2023-02-03</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockIncludingCommitmentSharesMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2019Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommonStockIncludingCommitmentSharesMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2020-10-01</xbrli:startDate>
        <xbrli:endDate>2021-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockExcludingCommitmentSharesMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2019Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommonStockExcludingCommitmentSharesMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2020-10-01</xbrli:startDate>
        <xbrli:endDate>2021-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_us-gaap_CommonStockMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2019Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2020-10-01</xbrli:startDate>
        <xbrli:endDate>2021-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_custom_CommitmentSharesMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2019Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommitmentSharesMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2020-10-01</xbrli:startDate>
        <xbrli:endDate>2021-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2019Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-10-012022-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2019Member</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-10-01</xbrli:startDate>
        <xbrli:endDate>2022-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_custom_StockOptionPlan2015Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis">avxl:StockOptionPlan2015Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_custom_StockOptionPlan2019Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis">avxl:StockOptionPlan2019Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-10-012022-09-30_custom_StockOptionPlan2022Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis">avxl:StockOptionPlan2022Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-10-01</xbrli:startDate>
        <xbrli:endDate>2022-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-03-242022-03-25_custom_StockOptionPlan2022Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis">avxl:StockOptionPlan2022Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-03-24</xbrli:startDate>
        <xbrli:endDate>2022-03-25</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_custom_StockOptionPlan2022Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis">avxl:StockOptionPlan2022Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_custom_PurchaseWarrants1Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis">avxl:PurchaseWarrants1Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_custom_PurchaseWarrants2Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis">avxl:PurchaseWarrants2Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2021-09-30_us-gaap_StockOptionMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2021-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-10-012022-09-30_us-gaap_StockOptionMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-10-01</xbrli:startDate>
        <xbrli:endDate>2022-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2022-09-30_us-gaap_StockOptionMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2022-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_us-gaap_StockOptionMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_us-gaap_StockOptionMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice1Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice1Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice2Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice2Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice3Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice3Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice4Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice4Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice5Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice5Member</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_us-gaap_GeneralAndAdministrativeExpenseMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis">us-gaap:GeneralAndAdministrativeExpenseMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-10-012022-09-30_us-gaap_GeneralAndAdministrativeExpenseMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis">us-gaap:GeneralAndAdministrativeExpenseMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-10-01</xbrli:startDate>
        <xbrli:endDate>2022-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2020-10-012021-09-30_us-gaap_GeneralAndAdministrativeExpenseMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis">us-gaap:GeneralAndAdministrativeExpenseMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2020-10-01</xbrli:startDate>
        <xbrli:endDate>2021-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_us-gaap_ResearchAndDevelopmentExpenseMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis">us-gaap:ResearchAndDevelopmentExpenseMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2021-10-012022-09-30_us-gaap_ResearchAndDevelopmentExpenseMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis">us-gaap:ResearchAndDevelopmentExpenseMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2021-10-01</xbrli:startDate>
        <xbrli:endDate>2022-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2020-10-012021-09-30_us-gaap_ResearchAndDevelopmentExpenseMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis">us-gaap:ResearchAndDevelopmentExpenseMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2020-10-01</xbrli:startDate>
        <xbrli:endDate>2021-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_custom_FederalMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">avxl:FederalMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2022-09-30_custom_FederalMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">avxl:FederalMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2022-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="From2022-10-012023-09-30_custom_FederalMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">avxl:FederalMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:startDate>2022-10-01</xbrli:startDate>
        <xbrli:endDate>2023-09-30</xbrli:endDate>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_us-gaap_StateAndLocalJurisdictionMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">us-gaap:StateAndLocalJurisdictionMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2022-09-30_us-gaap_StateAndLocalJurisdictionMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">us-gaap:StateAndLocalJurisdictionMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2022-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_us-gaap_ForeignCountryMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">us-gaap:ForeignCountryMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2023-09-30_us-gaap_ForeignCountryMember_currency_AUD">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">us-gaap:ForeignCountryMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:AUD</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2023-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2022-09-30_us-gaap_ForeignCountryMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">us-gaap:ForeignCountryMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2022-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2022-09-30_us-gaap_ForeignCountryMember_currency_AUD">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">us-gaap:ForeignCountryMember</xbrldi:explicitMember>
          <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:AUD</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2022-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2015-09-30_custom_FederalMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">avxl:FederalMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2015-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:context id="AsOf2021-09-30_custom_FederalMember">
      <xbrli:entity>
        <xbrli:identifier scheme="http://www.sec.gov/CIK">0001314052</xbrli:identifier>
        <xbrli:segment>
          <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">avxl:FederalMember</xbrldi:explicitMember>
        </xbrli:segment>
      </xbrli:entity>
      <xbrli:period>
        <xbrli:instant>2021-09-30</xbrli:instant>
      </xbrli:period>
    </xbrli:context>
    <xbrli:unit id="USD">
      <xbrli:measure>iso4217:USD</xbrli:measure>
    </xbrli:unit>
    <xbrli:unit id="Shares">
      <xbrli:measure>xbrli:shares</xbrli:measure>
    </xbrli:unit>
    <xbrli:unit id="USDPShares">
      <xbrli:divide>
        <xbrli:unitNumerator>
          <xbrli:measure>iso4217:USD</xbrli:measure>
        </xbrli:unitNumerator>
        <xbrli:unitDenominator>
          <xbrli:measure>xbrli:shares</xbrli:measure>
        </xbrli:unitDenominator>
      </xbrli:divide>
    </xbrli:unit>
    <xbrli:unit id="Pure">
      <xbrli:measure>xbrli:pure</xbrli:measure>
    </xbrli:unit>
  </ix:resources>
 </ix:header>
</div>


<p style="margin: 0"></p>

<!-- Field: Rule-Page --><div style="text-align: left; margin-top: 12pt; margin-bottom: 3pt"><div style="border-top: Black 2pt solid; border-bottom: Black 1pt solid; font-size: 1pt; width: 100%">&#160;</div></div><!-- Field: /Rule-Page -->

<p style="margin: 0">&#160;</p>

<p style="margin: 0"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font: 14pt Times New Roman, Times, Serif"><b>UNITED
STATES</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font: 14pt Times New Roman, Times, Serif"><b>SECURITIES
AND EXCHANGE COMMISSION</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font: 12pt Times New Roman, Times, Serif">Washington,
D.C. 20549</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font: 18pt Times New Roman, Times, Serif"><b>FORM
<span id="xdx_90A_edei--DocumentType_c20221001__20230930_zqeGaOoQQvs5"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:DocumentType">10-K</ix:nonNumeric></span></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><b>&#160;</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">(Mark One)</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Courier New, Courier, Monospace; margin: 0; text-align: center"><span style="font: 12pt Times New Roman, Times, Serif"><span id="xdx_90B_edei--DocumentAnnualReport_c20221001__20230930_ztHKvAPdoiCe"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" format="ixt:booleantrue" name="dei:DocumentAnnualReport">&#9746;</ix:nonNumeric></span>&#160;ANNUAL
REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">For the fiscal year ended <b><span style="text-decoration: underline"><span id="xdx_902_edei--DocumentPeriodEndDate_c20221001__20230930_z6UQAy0THiI2"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" format="ixt:datemonthdayyearen" name="dei:DocumentPeriodEndDate"><span id="xdx_90E_edei--CurrentFiscalYearEndDate_c20221001__20230930_zTDhHqb206Zh"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" format="ixt:datemonthdayen" name="dei:CurrentFiscalYearEndDate">September 30</ix:nonNumeric></span>,
2023</ix:nonNumeric></span></span></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><b>&#160;</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 12pt"><span id="xdx_90C_edei--DocumentTransitionReport_c20221001__20230930_z3H7Cbdny08"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" format="ixt:booleanfalse" name="dei:DocumentTransitionReport">&#9744;</ix:nonNumeric></span>&#160;TRANSITION
REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">For the transition period from ______________
to________________</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">Commission file number<b>: <span style="text-decoration: underline"><span id="xdx_90C_edei--EntityFileNumber_c20221001__20230930_zBwNo86NIL8h"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:EntityFileNumber">001-37606</ix:nonNumeric></span></span></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><b>&#160;</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><span style="font: 24pt Times New Roman, Times, Serif"><b><span style="text-decoration: underline"><span id="xdx_903_edei--EntityRegistrantName_c20221001__20230930_ziEvKOWQF2Eb"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:EntityRegistrantName">ANAVEX LIFE SCIENCES CORP.</ix:nonNumeric></span></span></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center">(Exact name of registrant as specified in its
charter)</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&#160;</p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Courier New, Courier, Monospace; width: 100%; border-collapse: collapse">
<tr style="vertical-align: top">
    <td style="border-bottom: windowtext 1pt solid; width: 49%; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif"><span id="xdx_90D_edei--EntityIncorporationStateCountryCode_c20221001__20230930_zQLHElYBBT7a"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" format="ixt-sec:stateprovnameen" name="dei:EntityIncorporationStateCountryCode">Nevada</ix:nonNumeric></span></span></td>
    <td style="width: 2%; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: windowtext 1pt solid; width: 49%; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif"><span id="xdx_909_edei--EntityTaxIdentificationNumber_c20221001__20230930_zb2Oywso5O2i"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:EntityTaxIdentificationNumber">98-0608404</ix:nonNumeric></span></span></td></tr>
<tr style="vertical-align: top">
    <td style="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">(State
    or other jurisdiction of incorporation or organization)</span></td>
    <td style="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">(I.R.S.
    Employer Identification No.)</span></td></tr>
<tr style="vertical-align: top">
    <td style="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="border-bottom: windowtext 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif"><span id="xdx_906_edei--EntityAddressAddressLine1_c20221001__20230930_zvgfQMXdyZSh"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:EntityAddressAddressLine1">630 5th Avenue</ix:nonNumeric></span>, <span id="xdx_90D_edei--EntityAddressAddressLine2_c20221001__20230930_zg1YrWJCbQdf"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:EntityAddressAddressLine2">20th Floor</ix:nonNumeric></span>, <span id="xdx_907_edei--EntityAddressCityOrTown_c20221001__20230930_zFwGCi2FR2W7"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:EntityAddressCityOrTown">New York</ix:nonNumeric></span>, <span id="xdx_90D_edei--EntityAddressStateOrProvince_c20221001__20230930_zX4BugB3hnY2"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:EntityAddressStateOrProvince">NY</ix:nonNumeric></span> <span id="xdx_90B_edei--EntityAddressCountry_c20221001__20230930_zRn5ZmDh74c9"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:EntityAddressCountry">US</ix:nonNumeric></span>A</span></td>
    <td style="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: windowtext 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif"><span id="xdx_901_edei--EntityAddressPostalZipCode_c20221001__20230930_zQh3POJbjsu5"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:EntityAddressPostalZipCode">10111</ix:nonNumeric></span></span></td></tr>
<tr style="vertical-align: top">
    <td style="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">(Address
    of principal executive offices)</span></td>
    <td style="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">(Zip
    Code)</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">Registrant&#8217;s telephone number, including
area code <span style="text-decoration: underline">1-<span id="xdx_90B_edei--CityAreaCode_c20221001__20230930_zdZB6RIG8cNd"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:CityAreaCode">844</ix:nonNumeric></span>-<span id="xdx_90E_edei--LocalPhoneNumber_c20221001__20230930_zLEn8N6tQj53"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:LocalPhoneNumber">689-3939</ix:nonNumeric></span></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center">Securities registered under Section 12(b) of
the Act:</p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Courier New, Courier, Monospace; width: 100%; border-collapse: collapse">
<tr style="vertical-align: top">
    <td style="border-bottom: windowtext 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center; width: 35%"><span style="font: 10pt Times New Roman, Times, Serif"><span id="xdx_90F_edei--Security12bTitle_c20221001__20230930_zolGYvY43gN8"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:Security12bTitle">Common
    Stock, $0.001 par value</ix:nonNumeric></span></span></td>
    <td style="border-bottom: windowtext 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center; width: 30%"><span style="font: 10pt Times New Roman, Times, Serif"><span id="xdx_905_edei--TradingSymbol_c20221001__20230930_z1gHEuM3z216"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:TradingSymbol">AVXL</ix:nonNumeric></span></span></td>
    <td style="border-bottom: windowtext 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center; width: 35%"><span style="font: 10pt Times New Roman, Times, Serif"><span id="xdx_90D_edei--SecurityExchangeName_c20221001__20230930_zEdKyU8YGqYj"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" format="ixt-sec:exchnameen" name="dei:SecurityExchangeName">NASDAQ</ix:nonNumeric></span>
    Stock Market LLC</span></td></tr>
<tr style="vertical-align: top">
    <td style="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">Title
    of each class</span></td>
    <td style="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">Trading
    Symbol</span></td>
    <td style="padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">Name
    of each exchange on which registered</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center">Securities registered pursuant to Section 12(g)
of the Act:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><b><span style="text-decoration: underline">None</span></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><b></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center">(Title of class)</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Courier New, Courier, Monospace; width: 100%; border-collapse: collapse">
<tr style="vertical-align: top">
    <td colspan="2" style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Indicate
    by checkmark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act.</span></td></tr>
<tr style="vertical-align: top">
    <td style="padding: 0pt; width: 75%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="padding: 0pt; text-align: right; width: 25%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_904_edei--EntityWellKnownSeasonedIssuer_c20221001__20230930_zTFbLQtNkAA4"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:EntityWellKnownSeasonedIssuer">Yes</ix:nonNumeric></span>&#160;&#9746;
    No&#160;&#9744;</span></td></tr>
<tr style="vertical-align: top">
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td colspan="2" style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Indicate
    by checkmark if the registrant is not required to file reports pursuant to Section 13 or 15(d) of the Act.</span></td></tr>
<tr style="vertical-align: top">
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="padding: 0pt; text-align: right; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Yes&#160;&#9744;
    <span id="xdx_90C_edei--EntityVoluntaryFilers_c20221001__20230930_zuM25fofcrkc"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:EntityVoluntaryFilers">No</ix:nonNumeric></span>&#9746;</span></td></tr>
<tr style="vertical-align: top">
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td colspan="2" style="padding: 0pt; text-align: justify; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Indicate
    by checkmark whether the registrant has (1) filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange
    Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and
    (2) has been subject to such filing requirements for the past 90 days.</span></td></tr>
<tr style="vertical-align: top">
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="padding: 0pt; text-align: right; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90C_edei--EntityCurrentReportingStatus_c20221001__20230930_zOgFlq3czQT5"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:EntityCurrentReportingStatus">Yes</ix:nonNumeric></span>&#160;&#9746;
    No&#160;&#9744;</span></td></tr>
</table>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<!-- Field: Page; Sequence: 1 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="text-align: center; margin-top: 0pt; margin-bottom: 0pt"></p></div>
    <div style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; border-collapse: collapse">
<tr style="vertical-align: top">
    <td colspan="2" style="font: 10pt Courier New, Courier, Monospace; padding: 0pt; text-align: justify; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif">Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (&#167;232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).</span></td></tr>
<tr style="vertical-align: top">
    <td style="font: 10pt Courier New, Courier, Monospace; padding: 0pt; width: 75%; text-indent: 0pt">&#160;</td>
    <td style="font: 10pt Courier New, Courier, Monospace; padding: 0pt; text-align: right; width: 25%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif"><span id="xdx_902_edei--EntityInteractiveDataCurrent_c20221001__20230930_zWltizb74COe"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:EntityInteractiveDataCurrent">Yes</ix:nonNumeric></span>&#160;&#9746;No&#160;&#9744;</span></td></tr>
<tr style="vertical-align: top">
    <td style="font: 10pt Courier New, Courier, Monospace; padding: 0pt; text-indent: 0pt">&#160;</td>
    <td style="font: 10pt Courier New, Courier, Monospace; padding: 0pt; text-indent: 0pt">&#160;</td></tr>
<tr style="vertical-align: top">
    <td colspan="2" style="padding: 0pt; text-indent: 0pt">
        <p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Indicate by checkmark whether the registrant is a large accelerated
        filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions
        of &#8220;large accelerated filer,&#8221; &#8220;accelerated filer&#8221;, &#8220;smaller reporting company&#8221; and &#8220;emerging
        growth company&#8221; in Rule 12b-2 of the Exchange Act.</p>
        <p style="font: 10pt Times New Roman, Times, Serif; margin: 0"></p></td></tr>
</table>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Courier New, Courier, Monospace; width: 100%; border-collapse: collapse">
<tr>
    <td style="padding: 0pt; width: 29%; text-align: left; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90F_edei--EntityFilerCategory_c20221001__20230930_z06rDN73J0T2"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" format="ixt-sec:entityfilercategoryen" name="dei:EntityFilerCategory">Large accelerated filer</ix:nonNumeric></span>&#9;&#9746;</span></td>
    <td style="padding: 0pt; vertical-align: top; width: 39%; text-align: center; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="padding: 0pt; vertical-align: top; width: 32%; text-align: right; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accelerated
    filer &#9744;</span></td></tr>
<tr>
    <td style="padding: 0pt; text-align: left; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Non-accelerated
    filer&#9;&#9744;</span></td>
    <td style="padding: 0pt; vertical-align: top; text-align: center; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="padding: 0pt; text-align: right; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Smaller
    reporting company <span id="xdx_905_edei--EntitySmallBusiness_c20221001__20230930_zTfj556lagV3"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" format="ixt:booleanfalse" name="dei:EntitySmallBusiness">&#9744;</ix:nonNumeric></span></span></td></tr>
<tr>
    <td style="padding: 0pt; text-align: left; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="padding: 0pt; vertical-align: top; text-align: center; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="padding: 0pt; text-align: right; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Emerging
    growth company<span id="xdx_90E_edei--EntityEmergingGrowthCompany_c20221001__20230930_zNc4pwbs1a9h"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" format="ixt:booleanfalse" name="dei:EntityEmergingGrowthCompany">&#9744;</ix:nonNumeric></span></span></td></tr>
</table>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; border-collapse: collapse">
<tr>
    <td colspan="2" style="padding: 0pt; text-indent: 0pt"><p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">If
                                            an emerging growth company, indicate by check mark if the registrant has elected not to use
                                            the extended transition period for complying with any new or revised financial accounting
                                            standards provided pursuant to Section 13(a) of the Exchange Act</span></p>
        <p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>
        <p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</span></p></td></tr>
<tr>
    <td colspan="2" style="padding: 0pt; text-indent: 0pt"><p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>
        <p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Indicate
        by check mark whether the registrant has filed a report on and attestation to its management&#8217;s assessment of the effectiveness
        of its internal controls over financial reporting under Section&#160;404(b) of the Sarbanes-Oxley Act (15 U.S.C. 7262(b)) by
        the registered public accounting firm that prepared or issued its audit report.</span></p>
        <p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>
        <p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Yes&#160;<span id="xdx_908_edei--IcfrAuditorAttestationFlag_c20221001__20230930_zcgllwPvqFb3"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" format="ixt:booleantrue" name="dei:IcfrAuditorAttestationFlag">&#9746;</ix:nonNumeric></span>No&#160;&#9744;&#160;&#160;</span></p></td></tr>
<tr>
    <td colspan="2" style="font: 10pt/115% Times New Roman, Times, Serif; padding: 0pt; text-align: justify; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">If
    securities are registered pursuant to Section 12(b) of the Act, indicate by check mark whether the financial statements of the registrant
    included in the filing reflect the correction of an error to previously issued financial statements</span></td></tr>
<tr>
    <td style="font: 10pt Courier New, Courier, Monospace; padding: 0pt; width: 75%; text-align: center; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font: 10pt Courier New, Courier, Monospace; padding: 0pt; vertical-align: top; width: 25%; text-align: right; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_900_edei--DocumentFinStmtErrorCorrectionFlag_c20221001__20230930_z43eLn0yPKb5"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" format="ixt:booleanfalse" name="dei:DocumentFinStmtErrorCorrectionFlag">&#9744;</ix:nonNumeric></span></span></td></tr>
<tr>
    <td style="font: 10pt Courier New, Courier, Monospace; padding: 0pt; text-align: center; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font: 10pt Courier New, Courier, Monospace; padding: 0pt; vertical-align: top; text-align: center; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr>
    <td colspan="2" style="padding: 0pt; text-indent: 0pt"><p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Indicate
                                            by check mark whether any of those error corrections are restatements that required a recovery
                                            analysis of incentive-based compensation received by any of the registrant&#8217;s executive
                                            officers during the relevant recovery period pursuant to &#167;240.10D-1(b).&#160;</span></p></td></tr>
<tr>
    <td style="font: 10pt Courier New, Courier, Monospace; padding: 0pt; text-align: center; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font: 10pt Courier New, Courier, Monospace; padding: 0pt; vertical-align: top; text-align: right; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</span></td></tr>
<tr>
    <td colspan="2" style="font: 10pt/115% Times New Roman, Times, Serif; padding: 0pt; text-align: justify; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr>
    <td colspan="2" style="font: 10pt Courier New, Courier, Monospace; padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Indicate
    by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Act).</span></td></tr>
<tr>
    <td style="font: 10pt Courier New, Courier, Monospace; padding: 0pt; text-align: center; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font: 10pt Courier New, Courier, Monospace; padding: 0pt; vertical-align: top; text-align: right; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Yes&#160;<span id="xdx_90C_edei--EntityShellCompany_c20221001__20230930_zb6cTeFtAvtl"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" format="ixt:booleanfalse" name="dei:EntityShellCompany">&#9744;</ix:nonNumeric></span>
    No&#160;&#9746;</span></td></tr>
</table>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;State the aggregate market value of the
voting and non-voting common equity held by non-affiliates computed by reference to the price at which the common equity was last
sold, or the average bid and asked price of such common equity, as of the last business day of the registrant&#8217;s most recently
completed second fiscal quarter: $<span id="xdx_90B_edei--EntityPublicFloat_iI_pn6n6_c20230331_z85ESxRSJ4O1"><ix:nonFraction name="dei:EntityPublicFloat" contextRef="AsOf2023-03-31" format="ixt:numdotdecimal" decimals="-6" scale="6" unitRef="USD">667</ix:nonFraction></span> million based on a price of $8.57 per share, being the closing price of the registrant&#8217;s
common stock on March 31, 2023.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 14.2pt; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Indicate the number of shares outstanding of
each of the registrant&#8217;s classes of common stock, as of the latest practicable date: <span id="xdx_903_edei--EntityCommonStockSharesOutstanding_iI_c20231124_zAyMEVM2Jv51"><ix:nonFraction name="dei:EntityCommonStockSharesOutstanding" contextRef="AsOf2023-11-24" format="ixt:numdotdecimal" decimals="INF" unitRef="Shares">82,086,511</ix:nonFraction></span> issued and outstanding as
of November 24, 2023.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center">DOCUMENTS INCORPORATED BY REFERENCE</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">None.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"></p>

<!-- Field: Page; Sequence: 2; Options: NewSection; Value: 2 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="text-align: center; margin-top: 0pt; margin-bottom: 0pt"><!-- Field: Sequence; Type: LowerRoman; Name: PageNo -->ii<!-- Field: /Sequence --></p></div>
    <div style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><b><span style="text-decoration: underline">TABLE OF CONTENTS</span></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: center"><b>&#160;</b></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td style="width: 90%"><a href="#a_001"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">PART I</span></a></td>
    <td style="text-align: right; width: 10%"><span style="font: 10pt Times New Roman, Times, Serif">6</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td><a href="#a_002"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 1. BUSINESS</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">6</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td><a href="#a_003"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 1A. RISK FACTORS</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">32</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td><a href="#a_004"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 1B. UNRESOLVED STAFF COMMENTS</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">60</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td><a href="#a_005"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 2. PROPERTIES</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">60</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td><a href="#a_006"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 3. LEGAL PROCEEDINGS</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">60</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td><a href="#a_007"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 4. MINE SAFETY DISCLOSURES</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">61</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td><a href="#a_008"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">PART II</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">61</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td style="text-align: justify"><a href="#a_009"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 5. MARKET FOR REGISTRANT&#8217;S COMMON EQUITY, RELATED STOCKHOLDER MATTERS AND ISSUER PURCHASES OF EQUITY SECURITIES</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">61</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td style="text-align: justify"><a href="#a_010"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 7 MANAGEMENT&#8217;S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATION</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">61</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td><a href="#a_011"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 7A QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">67</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td><a href="#a_012"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 8. FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">F-1</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td style="text-align: justify"><a href="#a_013"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 9. CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND FINANCIAL MATTERS</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">69</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td><a href="#a_014"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 9A. CONTROLS AND PROCEDURES</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">69</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td><a href="#a_015"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 9B OTHER INFORMATION</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">70</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td style="text-align: justify"><a href="#a_016"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 9C DISCLOSURE REGARDING FOREIGN JURISDICTIONS THAT PREVENT INSPECTIONS</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">70</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td><a href="#a_017"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">PART III</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">70</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td><a href="#a_018"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 10 DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">70</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td><a href="#a_019"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 11. EXECUTIVE COMPENSATION</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">74</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td style="text-align: justify"><a href="#a_020"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 12. SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS.</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">82</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><a href="#a_021">ITEM 13. CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR INDEPENDENCE</a></span></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">86</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td><a href="#a_022"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 14. PRINCIPAL ACCOUNTING FEES AND SERVICES</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">86</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td><a href="#a_023"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">PART IV</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">88</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td><a href="#a_024"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 15. EXHIBITS, FINANCIAL STATEMENT SCHEDULES</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">88</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td><a href="#a_025"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">ITEM 16. FORM 10-K SUMMARY</span></a></td>
    <td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">89</span></td></tr>
  </table>

<p style="font: bold 10pt/normal Times New Roman, Times, Serif; margin: 0; color: #365F91">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"></p>

<!-- Field: Page; Sequence: 3; Value: 2 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="text-align: center; margin-top: 0pt; margin-bottom: 0pt"><!-- Field: Sequence; Type: LowerRoman; Name: PageNo -->iii<!-- Field: /Sequence --></p></div>
    <div style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>Forward Looking Statements.</i></p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">This Annual Report on Form 10-K includes
forward-looking statements. All statements other than statements of historical facts contained in this Annual Report on Form 10-K,
including statements regarding our anticipated future clinical and regulatory milestone events, future financial position, business
strategy and plans and objectives of management for future operations, are forward-looking statements. The words &#8220;believe,&#8221;
&#8220;may,&#8221; &#8220;estimate,&#8221; &#8220;continue,&#8221; &#8220;anticipate,&#8221; &#8220;intend,&#8221; &#8220;expect,&#8221;
&#8220;should,&#8221; &#8220;forecast,&#8221; &#8220;potential,&#8221; &#8220;predict,&#8221; &#8220;could,&#8221; &#8220;would&#8221;,
&#8220;will&#8221;, &#8220;suggest,&#8221; &#8220;plan&#8221; and similar expressions, as they relate to us, are intended to identify
forward-looking statements. Such forward-looking statements include, without limitation, statements regarding:</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">volatility
                                                                                                                                    in
                                                                                                                                    our
                                                                                                                                    stock
                                                                                                                                    price
                                                                                                                                    and
                                                                                                                                    in
                                                                                                                                    the
                                                                                                                                    markets
                                                                                                                                    in
                                                                                                                                    general;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  successfully
                                                                                                                                  conduct
                                                                                                                                  preclinical
                                                                                                                                  studies
                                                                                                                                  and
                                                                                                                                  clinical
                                                                                                                                  trials
                                                                                                                                  for
                                                                                                                                  our
                                                                                                                                  product
                                                                                                                                  candidates;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  raise
                                                                                                                                  additional
                                                                                                                                  capital
                                                                                                                                  on
                                                                                                                                  favorable
                                                                                                                                  terms
                                                                                                                                  and
                                                                                                                                  the
                                                                                                                                  impact
                                                                                                                                  of
                                                                                                                                  such
                                                                                                                                  activities
                                                                                                                                  on
                                                                                                                                  our
                                                                                                                                  stockholders
                                                                                                                                  and
                                                                                                                                  stock
                                                                                                                                  price;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  generate
                                                                                                                                  any
                                                                                                                                  revenue
                                                                                                                                  or
                                                                                                                                  to
                                                                                                                                  continue
                                                                                                                                  as
                                                                                                                                  a
                                                                                                                                  going
                                                                                                                                  concern;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  execute
                                                                                                                                  our
                                                                                                                                  research
                                                                                                                                  and
                                                                                                                                  development
                                                                                                                                  plan
                                                                                                                                  on
                                                                                                                                  time
                                                                                                                                  and
                                                                                                                                  on
                                                                                                                                  budget;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  product
                                                                                                                                  candidates&#8217;
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  demonstrate
                                                                                                                                  efficacy
                                                                                                                                  or
                                                                                                                                  an
                                                                                                                                  acceptable
                                                                                                                                  safety
                                                                                                                                  profile;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  obtain
                                                                                                                                  the
                                                                                                                                  support
                                                                                                                                  of
                                                                                                                                  qualified
                                                                                                                                  scientific
                                                                                                                                  collaborators;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  ability,
                                                                                                                                  whether
                                                                                                                                  alone
                                                                                                                                  or
                                                                                                                                  with
                                                                                                                                  commercial
                                                                                                                                  partners,
                                                                                                                                  to
                                                                                                                                  successfully
                                                                                                                                  commercialize
                                                                                                                                  any
                                                                                                                                  of
                                                                                                                                  our
                                                                                                                                  product
                                                                                                                                  candidates
                                                                                                                                  that
                                                                                                                                  may
                                                                                                                                  be
                                                                                                                                  approved
                                                                                                                                  for
                                                                                                                                  sale;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  identify
                                                                                                                                  and
                                                                                                                                  obtain
                                                                                                                                  additional
                                                                                                                                  product
                                                                                                                                  candidates;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  reliance
                                                                                                                                  on
                                                                                                                                  third
                                                                                                                                  parties
                                                                                                                                  in
                                                                                                                                  non-clinical
                                                                                                                                  studies
                                                                                                                                  and
                                                                                                                                  clinical
                                                                                                                                  trials;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  defend
                                                                                                                                  against
                                                                                                                                  product
                                                                                                                                  liability
                                                                                                                                  claims;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  safeguard
                                                                                                                                  against
                                                                                                                                  security
                                                                                                                                  breaches;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  obtain
                                                                                                                                  and
                                                                                                                                  maintain
                                                                                                                                  sufficient
                                                                                                                                  intellectual
                                                                                                                                  property
                                                                                                                                  protection
                                                                                                                                  for
                                                                                                                                  our
                                                                                                                                  product
                                                                                                                                  candidates;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  comply
                                                                                                                                  with
                                                                                                                                  our
                                                                                                                                  intellectual
                                                                                                                                  property
                                                                                                                                  licensing
                                                                                                                                  agreements;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  defend
                                                                                                                                  against
                                                                                                                                  claims
                                                                                                                                  of
                                                                                                                                  intellectual
                                                                                                                                  property
                                                                                                                                  infringement;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  comply
                                                                                                                                  with
                                                                                                                                  the
                                                                                                                                  maintenance
                                                                                                                                  requirements
                                                                                                                                  of
                                                                                                                                  the
                                                                                                                                  government
                                                                                                                                  patent
                                                                                                                                  agencies;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  protect
                                                                                                                                  our
                                                                                                                                  intellectual
                                                                                                                                  property
                                                                                                                                  rights
                                                                                                                                  throughout
                                                                                                                                  the
                                                                                                                                  world;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">competition;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">the
                                                                                                                                  anticipated
                                                                                                                                  start
                                                                                                                                  dates,
                                                                                                                                  durations
                                                                                                                                  and
                                                                                                                                  completion
                                                                                                                                  dates
                                                                                                                                  of
                                                                                                                                  our
                                                                                                                                  ongoing
                                                                                                                                  and
                                                                                                                                  future
                                                                                                                                  clinical
                                                                                                                                  trials;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">the
                                                                                                                                  anticipated
                                                                                                                                  designs
                                                                                                                                  of
                                                                                                                                  our
                                                                                                                                  future
                                                                                                                                  clinical
                                                                                                                                  trials;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  attract
                                                                                                                                  and
                                                                                                                                  retain
                                                                                                                                  qualified
                                                                                                                                  employees;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">the
                                                                                                                                  impact
                                                                                                                                  of
                                                                                                                                  Fast
                                                                                                                                  Track
                                                                                                                                  designation
                                                                                                                                  on
                                                                                                                                  receipt
                                                                                                                                  of
                                                                                                                                  actual
                                                                                                                                  FDA
                                                                                                                                  approval;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  anticipated
                                                                                                                                  future
                                                                                                                                  regulatory
                                                                                                                                  submissions
                                                                                                                                  and
                                                                                                                                  our
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  receive
                                                                                                                                  regulatory
                                                                                                                                  approvals
                                                                                                                                  to
                                                                                                                                  develop
                                                                                                                                  and
                                                                                                                                  market
                                                                                                                                  our
                                                                                                                                  product
                                                                                                                                  candidates,
                                                                                                                                  including
                                                                                                                                  any
                                                                                                                                  orphan
                                                                                                                                  drug
                                                                                                                                  or
                                                                                                                                  Fast
                                                                                                                                  Track
                                                                                                                                  designations;
                                                                                                                                  and</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 20.65pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">our
                                                                                                                                  anticipated
                                                                                                                                  future
                                                                                                                                  cash
                                                                                                                                  position
                                                                                                                                  and
                                                                                                                                  ability
                                                                                                                                  to
                                                                                                                                  obtain
                                                                                                                                  funding
                                                                                                                                  for
                                                                                                                                  our
                                                                                                                                  operations.</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 38.65pt; text-align: justify; text-indent: -18pt">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">We have based these forward-looking
statements largely on our current expectations and projections about future events, including the responses we expect from the
U.S. Food and Drug Administration, (&#8220;FDA&#8221;), and other regulatory authorities and financial trends that we believe may
affect our financial condition, results of operations, business strategy, preclinical studies and clinical trials, and financial
needs. These forward-looking statements are subject to a number of risks, uncertainties and assumptions including, without limitation,
the risks described in &#8220;Risk Factors&#8221; in Part I, Item 1A of this Annual Report on Form 10-K. These risks are not exhaustive.
Other sections of this Annual Report on Form 10-K include additional factors which could adversely impact our business and financial
performance. Moreover, we operate in a very competitive and rapidly changing environment. New risk factors emerge from time to
time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our
business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those
contained in any forward-looking statements. You should not rely upon forward-looking statements as predictions of future events.
We cannot assure you that the events and circumstances reflected in the forward-looking statements will be achieved or occur and
actual results could differ materially from those projected in the forward-looking statements. Except as required by applicable
laws including the securities laws of the United States, we assume no obligation to update or supplement forward-looking statements.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">As used in this Annual Report on Form
10-K, the terms &#8220;we,&#8221; &#8220;us,&#8221; &#8220;our,&#8221;, &#8220;Company&#8221; and &#8220;Anavex&#8221; mean Anavex
Life Sciences Corp., unless the context clearly requires otherwise.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 4; Value: 2 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="text-align: center; margin-top: 0pt; margin-bottom: 0pt"><!-- Field: Sequence; Type: LowerRoman; Name: PageNo -->iv<!-- Field: /Sequence --></p></div>
    <div style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span id="a_001"></span>PART I</p>

<p style="font: bold 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_002"></span>ITEM 1. BUSINESS
</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Overview and Strategy</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Anavex Life Sciences Corp. is a clinical stage
biopharmaceutical company engaged in the development of differentiated therapeutics by applying precision medicine to central nervous
system (&#8220;CNS&#8221;) diseases with high unmet need. We analyze genomic data from clinical trials to identify biomarkers,
which we use in the analysis of our clinical trials.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Our lead product candidate, ANAVEX<sup>&#174;</sup>2-73
(blarcamesine), is being developed to treat Alzheimer&#8217;s disease, Parkinson&#8217;s disease and potentially other central
nervous system diseases, including rare diseases, such as Rett syndrome, a rare severe neurological monogenic disorder caused by
mutations in the X-linked gene, methyl-CpG-binding protein 2 (&#8220;MECP2&#8221;).</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We currently have two core programs and two
seed programs. Our core programs are at various stages of clinical and preclinical development, in neurodegenerative and neurodevelopmental
diseases.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">The following table summarizes key information about our programs:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; text-align: center; margin-bottom: 0"><img src="image_001.gif" alt="" />&#160;</p>

<p style="font: 12pt Times New Roman, Times, Serif; margin-top: 0; text-align: center; margin-bottom: 0"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>* = Orphan Drug Designation by the FDA;
1. EXCELLENCE: Ongoing trial </i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>&#160;</i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Anavex has a portfolio of compounds varying
in sigma-1 receptor (SIGMAR1) binding activities. The SIGMAR1 gene encodes the SIGMAR1 protein, which is an intracellular chaperone
protein with important roles in cellular communication. SIGMAR1 is also involved in transcriptional regulation at the nuclear envelope
and restores homeostasis and stimulates recovery of cell function when activated. In order to validate the ability of our compounds
to activate quantitatively the SIGMAR1, we performed, in collaboration with Stanford University, a quantitative Positron Emission
Tomography (PET) imaging scan in mice, which demonstrated a dose-dependent ANAVEX<sup>&#174;</sup>2-73 (blarcamesine) target engagement
or receptor occupancy with SIGMAR1 in the brain.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 5; Options: NewSection; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->6<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><img src="image_002.gif" alt="" />&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 12pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><i>Source: Reyes S et al., Sci Rep. 2021 Aug 25;11(1):17150</i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Cellular Homeostasis</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Many diseases are possibly directly caused
by chronic homeostatic imbalances or cellular stress of brain cells. In pediatric diseases, such as Rett syndrome or infantile
spasms, the chronic cellular stress is possibly caused by the presence of a constant genetic mutation. In neurodegenerative diseases,
such as Alzheimer&#8217;s and Parkinson&#8217;s diseases, chronic cellular stress is possibly caused by age-correlated buildup
of cellular insult and hence chronic cellular stress. Specifically, defects in homeostasis of protein or ribonucleic acid (&#8220;RNA&#8221;)
lead to the death of neurons and dysfunction of the nervous system. The spreading of protein aggregates resulting in a proteinopathy,
a characteristic found in Alzheimer&#8217;s and Parkinson&#8217;s diseases that results from disorders of protein synthesis, trafficking,
folding, processing or degradation in cells. The clearance of macromolecules in the brain is particularly susceptible to imbalances
that result in aggregation and degeneration in nerve cells. For example, Alzheimer&#8217;s disease pathology is characterized by
the presence of amyloid plaques, and neurofibrillary tangles, which are aggregates of hyperphosphorylated Tau protein that are
a marker of other diseases known as tauopathies as well as inflammation of microglia. With the SIGMAR1 activation through SIGMAR1
agonists like ANAVEX<sup>&#174;</sup>2-73 (blarcamesine), our approach is to restore cellular balance (i.e. homeostasis). Therapies
that correct defects in cellular homeostasis might have the potential to halt or delay neurodevelopmental and neurodegenerative
disease progression.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 6; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->7<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><b><i>ANAVEX</i></b><sup>&#174;</sup><b><i>2-73 (blarcamesine)-specific
Biomarkers</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">As part of some of our clinical trials, we
have incorporated a genomic analysis to better understand potential populations for whom our clinical programs might benefit. In
our clinical trials, a full genomic analysis of Alzheimer&#8217;s disease patients treated with ANAVEX<sup>&#174;</sup>2-73 (blarcamesine)
has helped us identify actionable genetic variants. A significant impact of the genomic biomarkers SIGMAR1, the direct target of
ANAVEX<sup>&#174;</sup>2-73 (blarcamesine) and COMT, a gene involved in memory function, on the drug response level was identified,
leading to an early ANAVEX<sup>&#174;</sup>2-73 (blarcamesine)-specific biomarker hypothesis. We believe that <i>excluding</i> patients
with SIGMAR1 identified biomarker variant (approximately 10%-20% of the population) in prospective studies would identify approximately
80%-90% patients that would display clinically significant improved functional and cognitive scores. The consistency between the
identified DNA and RNA data related to ANAVEX<sup>&#174;</sup>2-73 (blarcamesine), which are considered independent of Alzheimer&#8217;s
disease pathology, as well as multiple endpoints and time-points, provides support for the potential precision medicine clinical
development of ANAVEX<sup>&#174;</sup>2-73 (blarcamesine) by using genetic biomarkers identified within the trial population itself
to target patients who are most likely to respond to ANAVEX<sup>&#174;</sup>2-73 (blarcamesine) treatment. We may in the future
utilize such an approach in Alzheimer&#8217;s disease as well as indications like Parkinson&#8217;s disease dementia or Rett syndrome
in which ANAVEX<sup>&#174;</sup>2-73 (blarcamesine) is currently being studied.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><b><i>Clinical Trials Overview</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>Alzheimer&#8217;s Disease</i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In November 2016, we completed a Phase 2a clinical
trial, consisting of Part A and Part B, which lasted a total of 57 weeks, for ANAVEX<sup>&#174;</sup>2-73 in mild-to-moderate Alzheimer&#8217;s
patients. This open-label randomized trial in Australia met both primary and secondary endpoints and was designed to assess the
safety and exploratory efficacy of ANAVEX<sup>&#174;</sup>2-73 in 32 patients. ANAVEX<sup>&#174;</sup>2-73 targets sigma-1 and muscarinic
receptors, which have been shown in preclinical studies to reduce stress levels in the brain believed to restore cellular homeostasis
and to reverse the pathological hallmarks observed in Alzheimer&#8217;s disease. In October 2017, we presented positive pharmacokinetic
(&#8220;PK&#8221;) and pharmacodynamic (&#8220;PD&#8221;) data from the Phase 2a clinical trial, which established a concentration-effect
relationship between ANAVEX<sup>&#174;</sup>2-73 and trial measurements. These measures obtained from all patients who participated
in the entire 57 weeks include exploratory cognitive and functional scores as well as biomarker signals of brain activity. Additionally,
the clinical trial appeared to show that ANAVEX<sup>&#174;</sup>2-73 activity was enhanced by its active metabolite (ANAVEX19-144),
which also targets the SIGMAR1 receptor and has a half-life approximately twice as long as the parent molecule.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Two consecutive trial extensions for the Phase
2a trial have allowed participants who completed the 52-week Part B of the trial to continue taking ANAVEX<sup>&#174;</sup>2-73,
providing an opportunity to gather extended safety data for a cumulative time period of five years. In August 2020, patients completing
these Phase 2a trial extensions were granted continued access to treatment with ANAVEX<sup>&#174;</sup>2-73 through the Australian
Government Department of Health &#8211; Therapeutic Goods Administration&#8217;s compassionate use Special Access Scheme.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">A larger Phase 2b/3 double-blind, placebo-controlled
trial of ANAVEX<sup>&#174;</sup>2-73 in Alzheimer&#8217;s disease commenced in August 2018. The Phase 2b/3 trial enrolled 509 patients,
which were treated with a convenient once-daily oral formulation of ANAVEX<sup>&#174;</sup>2-73 for 48 weeks, randomized 1:1:1 to
two different ANAVEX<sup>&#174;</sup>2-73 doses or placebo. The trial took place at 52 sites across North America, Europe and Australia.
Primary and secondary endpoints to assess safety and both cognitive and functional efficacy, were measured through the Alzheimer&#8217;s
Disease Assessment Scale &#8211; Cognitive Subscale test (&#8220;ADAS-Cog&#8221;), Alzheimer&#8217;s Disease Cooperative Study
&#8211; Activities of Daily Living (&#8220;ADCS-ADL&#8221;) and Clinical Dementia Rating &#8211; Sum of Boxes for cognition and
function (&#8220;CDR-SB&#8221;). In addition to the primary endpoints, the ANAVEX<sup>&#174;</sup>2-73 Phase 2b/3 trial design incorporated
pre-specified statistical analyses related to potential genomic precision medicine biomarkers previously identified in the ANAVEX<sup>&#174;</sup>2-73
Phase 2a clinical trial. The trial was completed in mid-2022 and, in December 2022, the Company presented positive topline results
from the Phase 2b/3 clinical trial.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 7; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->8<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">ANAVEX<sup>&#174;</sup>2-73 met the co-primary
endpoints ADAS-Cog and ADCS-ADL and key secondary endpoint CDR-SB. ANAVEX<sup>&#174;</sup>2-73 treatment slowed decline of cognition
and function in patients with early Alzheimer&#8217;s disease over 48 weeks. Patients treated with ANAVEX<sup>&#174;</sup>2-73 had
1.84 times higher odds, or likelihood, to improve cognitively compared to placebo, with a ADAS-Cog score threshold change of -0.5
points or better [Odds Ratio = 1.84 (p = 0.015)]. At clinically significant levels of improvement in function (ADCS-ADL score threshold
change of +3.5 points or better), patients treated with ANAVEX<sup>&#174;</sup>2-73 had 2.67 times higher odds, or likelihood, to
improve function compared to placebo [Odds Ratio = 2.67 (p = 0.0255)]. <span style="color: black">Additionally, treatment with
ANAVEX<sup>&#174;</sup>2-73 reduced cognitive decline at end of treatment, measured with the ADAS-Cog, as compared to placebo, by
45%, representing a treatment difference in mean score change of -1.85 points (p=0.033). </span>Compared to placebo, ANAVEX<sup>&#174;</sup>2-73
reduced clinical decline of cognition and function by 27% with mean score difference of -0.42 points (p=0.040) as measured by the
CDR-SB. <span style="color: black">ANAVEX<sup>&#174;</sup>2-73 was generally safe and well tolerated. All statistical analyses were
performed by outside consultancy companies.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">In September 2023, we provided additional
data demonstrating that the clinical effect was complemented by two independent biomarkers. A significant reduction in pathological
amyloid beta levels in plasma, as well as a significant slowing in the rate of pathological brain atrophy on MRI (Magnetic Resonance
Imaging) scans. Validated biomarkers of amyloid beta pathology, plasma A&#946;42/40 ratio increased significantly (P = 0.048),
demonstrating strong anti-amyloid effects of ANAVEX<sup>&#174;</sup>2-73 in Alzheimer&#8217;s disease patients, while MRI revealed
significant reduction in brain volume loss, including whole brain (P = 0.0005), comparing treatment to placebo.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Furthermore, all prespecified clinical
endpoints were further analyzed using a mixed model for repeated measures (MMRM). Under the multiplicity control rule, a trial
is successful in meeting the co-primary endpoints if the significance of each endpoint is P &lt; 0.05, or if the significance of
only one co-primary endpoint is P &lt; 0.025. If only one primary endpoint is significant at an &#945; level of 0.025, then the
secondary endpoint will be evaluated at the same level of 0.025. The trial was successful, since the differences in the least-squares
mean (LSM) change from baseline to 48 weeks between the ANAVEX<sup>&#174;</sup>2-73 and placebo groups were &#8722;1.783 [95% CI,
&#8722;3.314 to &#8722;0.251]; (P = 0.0226) for ADAS-Cog13, and &#8722;0.456 [95% CI, &#8722;0.831 to &#8722;0.080]; (P = 0.0175)
for CDR-SB in patients with early Alzheimer&#8217;s disease.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">In the respective safety population,
common treatment-emergent adverse events included dizziness, which was transient and mostly mild to moderate in severity, and occurred
in 120 participants (35.8%) during titration and in 76 participants (25.2%) during maintenance with ANAVEX<sup>&#174;</sup>2-73
and 10 (6.0%) during titration and 9 (5.6%) during maintenance with placebo.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">A subsequent long-term open label extension
study of ANAVEX<sup>&#174;</sup>2-73, entitled the ATTENTION-AD trial was initiated for patients who have completed the 48-week
Phase 2b/3 placebo-controlled trial referenced above. This trial extension for an additional 96 weeks is currently ongoing, and
provides an opportunity to evaluate longer term safety and efficacy of ANAVEX<sup>&#174;</sup>2-73 in persons with Alzheimer&#8217;s
disease.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>Rett Syndrome </i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In February 2016, we presented positive preclinical
data for ANAVEX<sup>&#174;</sup>2-73 in Rett syndrome, a rare neurodevelopmental disease. The data demonstrated dose related and
significant improvements in an array of behavioral and gait paradigms in a mouse model with an MECP2-null mutation that causes
neurological symptoms that mimic Rett syndrome. The study was funded by the International Rett Syndrome Foundation (&#8220;Rettsyndrome.org&#8221;).
In January 2017, we were awarded a financial grant from Rettsyndrome.org of a minimum of $0.6 million to cover some of the costs
of a multicenter Phase 2 clinical trial of ANAVEX<sup>&#174;</sup>2-73 for the treatment of Rett syndrome. This award was received
in quarterly instalments which commenced during fiscal 2018.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 12pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In March 2019, we commenced the first Phase
2 clinical trial in a planned Rett syndrome program of ANAVEX<sup>&#174;</sup>2-73 for the treatment of Rett syndrome. The clinical
trials are being conducted in a range of patient age demographics and geographic regions, utilizing an oral liquid once-daily formulation
of ANAVEX<sup>&#174;</sup>2-73.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 8; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->9<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The first Phase 2 trial, (ANAVEX<sup>&#174;</sup>2-73-RS-001),
which took place in the United States, was completed in December 2020. This trial was a randomized double-blind, placebo-controlled
safety, tolerability, PK and efficacy trial of oral liquid ANAVEX<sup>&#174;</sup>2-73 formulation in 25 adult female patients with
Rett syndrome over a 7-week treatment period including ANAVEX<sup>&#174;</sup>2-73-specific genomic precision medicine biomarkers.
The primary endpoint of the trial was safety. The dosing of 5 mg ANAVEX<sup>&#174;</sup>2-73 was well-tolerated and demonstrated
dose-proportional PK. All secondary efficacy endpoints of the trial showed statistically significant and clinically meaningful
response in the Rett Syndrome Behaviour Questionnaire (&#8220;RSBQ&#8221;) response, when compared to placebo, in the intent to
treat (&#8220;ITT&#8221;) cohort (all participants, p = 0.011). 66.7% of ANAVEX<sup>&#174;</sup>2-73 treated subjects showed a statistically
significant improvement in RSBQ response as compared to 10% of the subjects on placebo in the ITT cohort (all participants, p =
0.011). ANAVEX<sup>&#174;</sup>2-73 treatment resulted in a sustained improvement in Clinical Global Impression Improvement (CGI-I)
response throughout the 7-week clinical trial, when compared to placebo in the ITT cohort (all participants, p = 0.014). Consistent
with previous ANAVEX<sup>&#174;</sup>2-73 clinical trials, patients carrying the common form of the SIGMAR1 gene treated with ANAVEX<sup>&#174;</sup>2-73
experienced stronger improvements in the prespecified efficacy endpoints.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="background-color: white">The
second, international trial of ANAVEX<sup>&#174;</sup>2-73 for the treatment of Rett syndrome, called the AVATAR trial, commenced
in June 2019.</span> This trial took place in Australia and the United Kingdom using a higher dose than the U.S. based Phase 2
trial for Rett syndrome. The trial was a Phase 3 randomized, double-blind, placebo-controlled trial to evaluate the safety and
efficacy of ANAVEX<sup>&#174;</sup>2-73 in 33 adult patients over a 7-week treatment period including ANAVEX<sup>&#174;</sup>2-73
specific precision medicine biomarkers. Based upon the input from the successful U.S. Phase 2 Rett syndrome trial (ANAVEX<sup>&#174;</sup>2-73-RS-001),
we updated the endpoints for the AVATAR trial (ANAVEX<sup>&#174;</sup>2-73-RS-002) to appropriately assess the clinically meaningful
outcome following International Conference on Harmonization (ICH) guidelines. These updates were approved by the respective regulatory
authorities in the U.K. and in Australia, respectively, where the AVATAR trial was conducted.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The data from the AVATAR trial was released
in February 2022. The clinical trial met all primary and secondary efficacy and safety endpoints, with consistent improvements
in primary efficacy endpoint, RSBQ response (p = 0.037), and secondary efficacy endpoints, ADAMS (p = 0.010) and CGI-I (p = 0.037)
response. Efficacy endpoints demonstrated statistically significant and clinically meaningful reductions in Rett syndrome symptoms.
Convenient once daily oral liquid doses of up to 30 mg of ANAVEX<sup>&#174;</sup>2-73 were also well tolerated with good medication
compliance. All patients who participated in the trial were eligible to receive ANAVEX<sup>&#174;</sup>2-73 under a voluntary open
label extension protocol.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In July 2020, we commenced the third trial
of ANAVEX<sup>&#174;</sup>2-73 for the treatment of Rett syndrome, called the EXCELLENCE trial. This Phase 2/3 trial in pediatric
patients with Rett syndrome includes trial sites in Australia, the United Kingdom and Canada, and will evaluate the safety and
efficacy of ANAVEX<sup>&#174;</sup>2-73 in approximately 84 pediatric patients, aged 5 to 18, over a 12-week treatment period incorporating
ANAVEX<sup>&#174;</sup>2-73 specific precision medicine biomarkers. This trial completed enrollment in February 2023, exceeding
the original enrollment target. In June 2023, this trial completed dosing of all participants, and topline results are expected
in the second half of 2023. All patients who participate in the trial will be eligible to receive ANAVEX<sup>&#174;</sup>2-73 under
a voluntary open label extension protocol, which is currently ongoing.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 12pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>Parkinson&#8217;s Disease</i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In September 2016, we presented positive preclinical
data for ANAVEX<sup>&#174;</sup>2-73 in an animal model of Parkinson&#8217;s disease, which demonstrated significant improvements
on behavioral, histopathological, and neuroinflammatory endpoints. The study was funded by the Michael J. Fox Foundation. Additional
data announced in October 2017 indicated that ANAVEX<sup>&#174;</sup>2-73 induced robust neurorestoration in experimental Parkinsonism.
We believe the encouraging results we have gathered in this preclinical model, coupled with the favorable profile of this product
candidate in the Alzheimer&#8217;s disease trial, support the notion that ANAVEX<sup>&#174;</sup>2-73 has the potential to treat
Parkinson&#8217;s disease dementia.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In October 2020, we completed a double-blind,
randomized, placebo-controlled proof-of-concept Phase 2 trial with ANAVEX<sup>&#174;</sup>2-73 in Parkinson&#8217;s disease dementia
in Spain and Australia, to study the effect of the compound on both the cognitive and motor impairment of Parkinson&#8217;s disease.
The Phase 2 trial enrolled approximately 132 patients for 14 weeks, randomized 1:1:1 to two different ANAVEX<sup>&#174;</sup>2-73
doses, 30 mg and 50 mg, or placebo. The ANAVEX<sup>&#174;</sup>2-73 Phase 2 Parkinson&#8217;s disease dementia trial design incorporated
genomic precision medicine biomarkers identified in the ANAVEX<sup>&#174;</sup>2-73 Phase 2a Alzheimer&#8217;s disease trial.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 9; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->10<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The trial demonstrated that ANAVEX<sup>&#174;</sup>2-73
was safe and well tolerated in oral doses up to 50 mg once daily. The results showed clinically meaningful, dose-dependent, and
statistically significant improvements in the Cognitive Drug Research (&#8220;CDR&#8221;) computerized assessment system analysis.
Treatment with ANAVEX<sup>&#174;</sup>2-73 also resulted in clinically meaningful improvements as measured by the global composite
score of Parkinson&#8217;s disease symptom severity, MDS-Unified Parkinson&#8217;s Disease Rating Scale (&#8220;MDS-UPDRS&#8221;)
total score on top of standard of care including dopaminergic therapy, levodopa and other anti-PD medications after 14 weeks of
treatment, suggesting ANAVEX<sup>&#174;</sup>2-73&#8217;s potential capability of slowing and reversing symptoms that progress in
Parkinson&#8217;s disease. In addition, the trial confirmed the precision medicine approach of targeting SIGMAR1 as a genetic biomarker
in response to ANAVEX<sup>&#174;</sup>2-73 may result in improved clinical outcomes.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">A 48-week Open Label Extension (&#8220;OLE&#8221;)
ANAVEX2-73-PDD-EP-001 Phase 2 trial was offered to participants after completion of the double-blind placebo-controlled ANAVEX2-73-PDD-001
Phase 2 trial discussed above. The OLE trial assessed safety, tolerability and efficacy, measuring among others, MDS-Unified Parkinson&#8217;s
Disease Rating Scale Parts I, II, III, REM Sleep Behavior Disorder Screening Questionnaire (RBDSQ), Clinical Global Impression
&#8211; Improvement (CGI-I), as well as cognitive efficacy endpoint Montreal Cognitive Assessment (MoCA) over a 48-week period.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In March 2023, we reported the preliminary
ANAVEX2-73-PDD-EP-001 OLE trial data, which demonstrated longitudinal beneficial effects of ANAVEX<sup>&#174;</sup>2-73 on the prespecified
primary and secondary objectives. Preliminary analysis reveals that ANAVEX<sup>&#174;</sup>2-73 was found to be generally safe and
well tolerated; and safety findings in this trial were consistent with the known safety profile of ANAVEX<sup>&#174;</sup>2-73.
In respect to efficacy, across all efficacy endpoints, patients performed better while on ANAVEX<sup>&#174;</sup>2-73. While all
patients were on drug holiday due to COVID-19 between the DB EOT and the OLE Baseline, the respective efficacy endpoints, including
the MDS-UPDRS Part II + III and CGI-I, measured at the end of trial of the double-blind study (DB EOT) and the OLE Baseline, were
worsening, as expected in a progressive disease like Parkinson&#8217;s. However, when patients resumed daily oral ANAVEX<sup>&#174;</sup>2-73
treatment, a consistent improvement was observed during the extension phase from OLE Baseline through OLE Week 24, and OLE Week
48, respectively. These results are consistent with the pattern observed for all efficacy measures in the extension phase. The
two endpoints, MDS-UPDRS Part II + III and CGI-I measured in this study are the planned primary and key secondary endpoints in
our forthcoming pivotal 6-month Parkinson&#8217;s disease study.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In January 2021, we were awarded a research
grant of $1.0 million from&#160;The Michael J. Fox Foundation for Parkinson&#8217;s Research&#160;to develop ANAVEX<sup>&#174;</sup>2-73
for the treatment of Parkinson&#8217;s disease. The award will explore utilization of PET imaging biomarkers to enable measurement
of target engagement and pathway activation of the SIGMAR1 with clinically relevant doses, including in people with Parkinson&#8217;s
disease.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>Schizophrenia, Frontotemporal Dementia and
Alzheimer&#8217;s disease</i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In July 2020, we commenced the First-in-Human
Phase 1 clinical trial of ANAVEX<sup>&#174;</sup>3-71. ANAVEX<sup>&#174;</sup>3-71 was previously granted orphan drug designation
for the treatment of Frontotemporal Dementia (&#8220;FTD&#8221;) by the FDA. ANAVEX<sup>&#174;</sup>3-71 is an orally administered
small molecule targeting sigma-1 and M1 muscarinic receptors that is designed to be beneficial for neurodegenerative diseases.
In preclinical studies, <span style="background-color: white">ANAVEX<sup>&#174;</sup>3-71 demonstrated disease-modifying activity
against the major hallmarks of Alzheimer&#8217;s disease in transgenic (3xTg-AD) mice, including cognitive deficits, amyloid and
tau pathologies, as well as beneficial effects on mitochondrial dysfunction and neuroinflammation.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="background-color: white">The Phase
1 clinical trial was a prospective double-blind, randomized, placebo-controlled trial in Australia. A total of 36 healthy male
and female subjects were included. Single escalating doses of ANAVEX<sup>&#174;</sup>3-71 were administered in order to evaluate
the safety, tolerability, and PK of ANAVEX<sup>&#174;</sup>3-71 and the effects of food and gender on its PK in healthy volunteers.
</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 10; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->11<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="background-color: white">The trial
met its primary and secondary endpoints of safety, with no serious adverse events (&#8220;SAEs&#8221;) or dose-limiting toxicities
observed. ANAVEX<sup>&#174;</sup>3-71 was well tolerated in all cohorts receiving ANAVEX<sup>&#174;</sup>3-71 in single doses ranging
from 5 mg to 200 mg daily with no SAEs and no significant lab abnormalities in any subject. In the trial, ANAVEX<sup>&#174;</sup>3-71
exhibited linear PK. Its pharmacokinetics was also dose proportional for doses up to 160 mg. Gender had no effect on the PK of
the drug and food had no effect on the bioavailability of ANAVEX<sup>&#174;</sup>3-71. The trial also met the secondary objective
of characterizing the effect of ANAVEX<sup>&#174;</sup>3-71 on electrocardiogram (&#8220;ECG&#8221;) parameters. There were no clinically
significant ECG parameters throughout the trial. Participant QTcF measures were normal across all dose groups with no difference
between ANAVEX<sup>&#174;</sup>3-71 and placebo.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="background-color: white">In October
2023 a peer-reviewed publication in the journal Neurobiology of Aging, titled &#8220;Early treatment with an M1 and sigma-1 receptor
agonist prevents cognitive decline in a transgenic rat model displaying Alzheimer-like amyloid pathology&#8221;, featured the orally
available small molecule ANAVEX<sup>&#174;</sup>3-71<i> (AF710B</i>). The preclinical study described the potential disease-modifying
properties of ANAVEX<sup>&#174;</sup>3-71 on Alzheimer&#8217;s disease pathology as a possible drug candidate for a potential once
daily oral preventive strategy for Alzheimer&#8217;s disease.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="background-color: white">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="background-color: white">Based
on these results, and ANAVEX<sup>&#174;</sup>3-71&#8217;s pre-clinical profile, we intend to advance ANAVEX<sup>&#174;</sup>3-71
into a biomarker-driven clinical development dementia program for the treatment of schizophrenia, FTD and Alzheimer&#8217;s disease,
evaluating longitudinal effect of treatment with ANAVEX<sup>&#174;</sup>3-71. We believe the results of these clinical trials and
preclinical study could serve as a basis for advancing into respective registration trials in the U.S.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Our Pipeline</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Our research and development pipeline includes
ANAVEX<sup>&#174;</sup>2-73 currently in three different clinical trial indications, and several other compounds in different stages
of clinical and pre-clinical development.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Our proprietary SIGMACEPTOR&#8482; Discovery
Platform produced small molecule drug candidates with unique modes of action, based on our understanding of sigma receptors. Sigma
receptors may be targets for therapeutics to combat many human diseases, both of neurodegenerative nature, including Alzheimer&#8217;s
disease, as well as of neurodevelopmental nature, like Rett syndrome. When bound by the appropriate ligands, sigma receptors influence
the functioning of multiple biochemical signals that are involved in the pathogenesis (origin or development) of disease. Multiple
viruses including SARS-CoV-2 (COVID-19) induce cellular stress by intrinsic mitochondrial apoptosis and other related cellular
processes, in order to ensure survival and replication. Hence, it is possible that SIGMAR1 could play a role in modulating the
cellular response to viral infection and ameliorate pathogenesis.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Compounds that have been subjects of our research
include the following:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">ANAVEX<sup>&#174;</sup>2-73 <i>(blarcamesine)</i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We believe ANAVEX<sup>&#174;</sup>2-73 may offer
a disease-modifying approach in neurodegenerative and neurodevelopmental diseases by activation of SIGMAR1. ANAVEX<sup>&#174;</sup>2-73
is being developed in an oral liquid once-daily formulation for rare diseases such as Rett syndrome as well as an oral once-daily
capsule formulation for diseases such as Alzheimer&#8217;s disease.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In Rett syndrome, administration of ANAVEX<sup>&#174;</sup>2-73
in liquid form resulted in both significant and dose related improvements in an array of behavioral paradigms in the MECP2 HET
Rett syndrome disease model. In addition, in a further experiment sponsored by Rettsyndrome.org, ANAVEX<sup>&#174;</sup>2-73 was
evaluated in automatic visual response and respiration tests in 7-month old mice, an age at which advanced pathology is evident.
Vehicle-treated MECP2 mice demonstrated fewer automatic visual responses than wild-type mice. Treatment with ANAVEX<sup>&#174;</sup>2-73
for four weeks significantly increased the automatic visual response in the MECP2 Rett syndrome disease mice. Additionally, chronic
oral dosing daily for 6.5 weeks of ANAVEX<sup>&#174;</sup>2-73 starting at ~5.5 weeks of age was conducted in the MECP2 HET Rett
syndrome disease mouse model assessed the different aspects of muscular coordination, balance, motor learning and muscular strengths,
some of the core deficits observed in Rett syndrome. Administration of ANAVEX<sup>&#174;</sup>2-73 resulted in both significant
and dose related improvements in an array of these behavioral paradigms in the MECP2 HET Rett syndrome disease model.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 11; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->12<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In May 2016 and June 2016, the FDA granted
Orphan Drug Designation to ANAVEX<sup>&#174;</sup>2-73 for the treatment of Rett syndrome and infantile spasms, respectively. In
November 2019, the FDA granted to ANAVEX<sup>&#174;</sup>2-73 the Rare Pediatric Disease (RPD) designation for the treatment of
Rett syndrome. The RPD designation is intended to encourage the development of treatments for rare pediatric diseases.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Further, in February 2020, the FDA granted
Fast Track designation for the ANAVEX<sup>&#174;</sup>2-73 clinical development program for the treatment of Rett syndrome. The
FDA Fast Track program is designed to facilitate and expedite the development and review of new drugs to address unmet medical
needs in the treatment of serious and life-threatening conditions.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">For Parkinson&#8217;s disease, data demonstrates
significant improvements and restoration of function in a disease-modifying animal model of Parkinson&#8217;s disease. Significant
improvements were seen on all measures tested: behavioral, histopathological, and neuroinflammatory endpoints. In October 2020,
we completed a double-blind, randomized, placebo-controlled proof-of-concept Phase 2 trial with ANAVEX<sup>&#174;</sup>2-73 in Parkinson&#8217;s
disease dementia, to study the effect of the compound on both the cognitive and motor impairment of Parkinson&#8217;s disease.
The Phase 2 trial enrolled approximately 132 patients for 14 weeks, randomized 1:1:1 to two different ANAVEX<sup>&#174;</sup>2-73
doses, 30mg and 50mg, or placebo. The ANAVEX<sup>&#174;</sup>2-73 Phase 2 Parkinson&#8217;s disease dementia trial design incorporated
genomic precision medicine biomarkers identified in the ANAVEX<sup>&#174;</sup>2-73 Phase 2a Alzheimer&#8217;s disease trial.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The trial demonstrated that ANAVEX<sup>&#174;</sup>2-73
was safe and well tolerated in oral doses up to 50mg once daily. The results showed clinically meaningful, dose-dependent, and
statistically significant improvements in the CDR computerized assessment system analysis. We anticipate conducting further clinical
trials of ANAVEX<sup>&#174;</sup>2-73 in Parkinson&#8217;s disease dementia after submitting the results of the trial to the FDA
to obtain regulatory guidance.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In Alzheimer&#8217;s disease animal models,
ANAVEX<sup>&#174;</sup>2-73 has shown pharmacological, histological and behavioral evidence as a potential neuroprotective, anti-amnesic,
anti-convulsive and anti-depressive therapeutic agent, due to its potent affinity to SIGMAR1 and moderate affinities to M1-4 type
muscarinic receptors. In addition, ANAVEX<sup>&#174;</sup>2-73 has shown a potential dual mechanism which may impact amyloid, tau
pathology and inflammation. In a transgenic Alzheimer&#8217;s disease animal model Tg2576, ANAVEX<sup>&#174;</sup>2-73 induced a
statistically significant neuroprotective effect against the development of oxidative stress in the mouse brain, as well as significantly
increased the expression of functional and synaptic plasticity markers that is apparently amyloid-beta independent. It also statistically
alleviated the learning and memory deficits developed over time in the animals, regardless of sex, both in terms of spatial working
memory and long-term spatial reference memory.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Based on the results of pre-clinical testing,
we initiated and completed a Phase 1 single ascending dose (SAD) clinical trial of ANAVEX<sup>&#174;</sup>2-73. In this Phase 1
SAD trial, the maximum tolerated single dose was defined per protocol as 55-60 mg. This dose is above the equivalent dose shown
to have positive effects in mouse models of Alzheimer&#8217;s disease. There were no significant changes in laboratory or ECG parameters.
ANAVEX<sup>&#174;</sup>2-73 was well tolerated below the 55-60 mg dose with only mild adverse events in some subjects. Observed
adverse events at doses above the maximum tolerated single dose included headache and dizziness, which were moderate in severity
and reversible. These side effects are often seen with drugs that target CNS conditions, including Alzheimer&#8217;s disease.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In November 2016, we completed a Phase 2a clinical
trial for ANAVEX<sup>&#174;</sup>2-73, for the treatment of Alzheimer&#8217;s disease. The open-label randomized trial was designed
to assess the safety and exploratory efficacy of ANAVEX<sup>&#174;</sup>2-73 in 32 patients with mild-to-moderate Alzheimer&#8217;s
disease. The Phase 2a trial met both primary and secondary objectives of the trial.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 12; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->13<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">In July 2018, we presented
the results of a genomic DNA and RNA evaluation of the participants in the Phase 2a clinical trial. More than 33,000 genes were
analyzed using unbiased, data driven, machine learning, artificial intelligence (AI) system for analyzing DNA and RNA data in patients
treated with ANAVEX<sup>&#174;</sup>2-73. The analysis identified genetic variants that impacted response to ANAVEX<sup>&#174;</sup>2-73,
among them variants related to the SIGMAR1, the target for ANAVEX<sup>&#174;</sup>2-73. Results showed that trial participants with
the common SIGMAR1 wild type gene variant, which is estimated to be about 80% of the population worldwide, demonstrated improved
cognitive (MMSE) and functional (ADCS-ADL) scores. The results from this evaluation supported the continued evaluation of genomic
information in subsequent clinical trials, since these signatures can now be applied to neurological indications tested in future
clinical trials with ANAVEX<sup>&#174;</sup>2-73 including Alzheimer&#8217;s disease, Parkinson&#8217;s disease dementia and Rett
syndrome.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">ANAVEX<sup>&#174;</sup>2-73
data met prerequisite information in order to progress into a Phase 2b/3 placebo-controlled trial. On July 2, 2018, the Human Research
Ethics Committee in Australia approved the initiation of our Phase 2b/3, double-blind, randomized, placebo-controlled 48-week safety
and efficacy trial of ANAVEX<sup>&#174;</sup>2-73 for the treatment of early Alzheimer&#8217;s disease. Clinical trial sites in
Canada, the United Kingdom, the Netherlands and Germany were also added. This Phase 2b/3 trial design incorporates inclusion of
genomic precision medicine biomarkers identified in the ANAVEX<sup>&#174;</sup>2-73 Phase 2a trial.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We believe preclinical data from our studies
also supports further research into the use of ANAVEX<sup>&#174;</sup>2-73 as a potential platform drug for other neurodegenerative
diseases beyond Alzheimer&#8217;s disease, Parkinson&#8217;s disease or Rett syndrome, more specifically, epilepsy, infantile spasms,
Fragile X syndrome, Angelman syndrome, multiple sclerosis, and, more recently, tuberous sclerosis complex (TSC). ANAVEX<sup>&#174;</sup>2-73
demonstrated significant improvements in all of these indications in the respective preclinical animal models.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In a preclinical study sponsored by the Foundation
for Angelman Syndrome, ANAVEX<sup>&#174;</sup>2-73 was assessed in a mouse model for the development of audiogenic seizures. The
results indicated that ANAVEX<sup>&#174;</sup>2-73 administration significantly reduced audiogenic-induced seizures in mice. In
a study sponsored by FRAXA Research Foundation regarding Fragile X syndrome, data demonstrated that ANAVEX<sup>&#174;</sup>2-73
restored hippocampal brain-derived neurotrophic factor (BDNF) expression to normal levels. BDNF under-expression has been observed
in many neurodevelopmental and neurodegenerative pathologies. BDNF signaling promotes maturation of both excitatory and inhibitory
synapses. ANAVEX<sup>&#174;</sup>2-73 normalization of BDNF expression could be a contributing factor for the positive preclinical
data observed in both neurodevelopmental and neurodegenerative disorders like Angelman and Fragile X syndromes.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In addition, preclinical data to-date also
indicates that ANAVEX<sup>&#174;</sup>2-73 has the potential to demonstrate protective effects of mitochondrial enzyme complexes
during pathological conditions, which, if impaired, may play a role in the pathogenesis of neurodegenerative and neurodevelopmental
diseases.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In addition, preclinical data on ANAVEX<sup>&#174;</sup>2-73
related to multiple sclerosis indicates that ANAVEX<sup>&#174;</sup>2-73 may promote remyelination in multiple sclerosis disease.
Further, our data also demonstrates that ANAVEX<sup>&#174;</sup>2-73 has the potential to provide protection for oligodendrocytes
(&#8220;OL&#8217;s&#8221;) and oligodendrocyte precursor cells (&#8220;OPC&#8217;s&#8221;), as well as central nervous system neurons
in addition to helping repair by increasing OPC proliferation and maturation in tissue culture.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In March 2018, we presented preclinical data
of ANAVEX<sup>&#174;</sup>2-73 in a genetic mouse model of tuberous sclerosis complex (&#8220;TSC&#8221;). TSC is a rare genetic
disorder characterized by the growth of numerous benign tumors in many parts of the body with a high incidence of seizures. The
preclinical data demonstrated that treatment with ANAVEX<sup>&#174;</sup>2-73 significantly increased survival and reduced seizures
in those mice.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>ANAVEX<sup>&#174;</sup>3-71</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">ANAVEX<sup>&#174;</sup>3-71 is a clinical drug
candidate with a novel mechanism of action via SIGMAR1 activation and M1 muscarinic allosteric modulation, which has been shown
to enhance neuroprotection and cognition in Alzheimer&#8217;s disease models. ANAVEX<sup>&#174;</sup>3-71 is a CNS-penetrable potential
disease-modifying treatment for cognitive impairments. We believe it is effective in very small doses against the major Alzheimer&#8217;s
hallmarks in transgenic (3xTg-AD) mice, including cognitive deficits, amyloid and tau pathologies, and also has beneficial effects
on inflammation and mitochondrial dysfunctions. ANAVEX<sup>&#174;</sup>3-71 indicates extensive therapeutic advantages in Alzheimer&#8217;s
and other protein-aggregation-related diseases given its ability to enhance neuroprotection and cognition via SIGMAR1 activation
and M1 muscarinic allosteric modulation.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 13; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->14<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">A preclinical study examined the response of
ANAVEX<sup>&#174;</sup>3-71 in aged transgenic animal models and showed a significant reduction in the rate of cognitive deficit,
amyloid beta pathology and inflammation with the administration of ANAVEX<sup>&#174;</sup>3-71. In April 2016, the FDA granted Orphan
Drug Designation to ANAVEX<sup>&#174;</sup>3-71 for the treatment of FTD.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">During pathological conditions ANAVEX<sup>&#174;</sup>3-71
demonstrated the formation of new synapses between neurons (synaptogenesis) without causing an abnormal increase in the number
of astrocytes. In neurodegenerative diseases such as Alzheimer&#8217;s and Parkinson&#8217;s disease, synaptogenesis is believed
to be impaired. Additional preclinical data presented also indicates that in addition to reducing oxidative stress, ANAVEX<sup>&#174;</sup>3-71
has the potential to demonstrate protective effects of mitochondrial enzyme complexes during pathological conditions, which, if
impaired, are believed to play a role in the pathogenesis of neurodegenerative and neurodevelopmental diseases.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In July 2020, we commenced the first Phase
1 clinical trial of&#160;ANAVEX<sup>&#174;</sup>3-71. The trial took place in Australia and was a double-blind, randomized, placebo-controlled,
Phase 1 trial to evaluate safety and tolerability, and PK of oral escalating doses of ANAVEX<span style="background-color: white"><sup>&#174;</sup></span>3-71
including effects of food and gender in healthy volunteers. <span style="background-color: white">The trial met its primary and
secondary endpoints of safety, respectively, with no serious adverse events (SAEs) or dose-limiting toxicities observed, </span>as
more fully described above under <i>Clinical Trials Overview &#8211; Frontotemporal Dementia</i>.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="background-color: white">Based
on these results, and ANAVEX<sup>&#174;</sup>3-71 pre-clinical profile, the Company intends to advance ANAVEX<sup>&#174;</sup>3-71
into a biomarker-driven clinical development dementia program for the treatment of schizophrenia, FTD and Alzheimer&#8217;s disease,
evaluating longitudinal effect of treatment with ANAVEX<sup>&#174;</sup>3-71. We believe the results of this clinical trial and
preclinical study could serve as a basis for advancing into respective registration trials in the U.S.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><b>ANAVEX<sup>&#174;</sup>1-41</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">ANAVEX<sup>&#174;</sup>1-41 is a sigma-1 agonist.
Pre-clinical tests revealed significant neuroprotective benefits (i.e., protects nerve cells from degeneration or death) through
the modulation of endoplasmic reticulum, mitochondrial and oxidative stress, which damages and impairs cell viability. In addition,
in animal models, ANAVEX<sup>&#174;</sup>1-41 prevented the expression of caspase-3, an enzyme that plays a key role in apoptosis
(programmed cell death) and loss of cells in the hippocampus, the part of the brain that regulates learning, emotion and memory.
These activities involve both muscarinic and SIGMAR1 systems through a novel mechanism of action.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Preclinical data presented also indicates that
ANAVEX<sup>&#174;</sup>1-41 has the potential to demonstrate protective effects of mitochondrial enzyme complexes during pathological
conditions, which, if impaired, are believed to play a role in the pathogenesis of neurodegenerative and neurodevelopmental diseases.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>ANAVEX<sup>&#174;</sup>1066</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">ANAVEX<sup>&#174;</sup>1066, a mixed sigma-1/sigma-2
ligand, is designed for the potential treatment of neuropathic and visceral pain. ANAVEX<sup>&#174;</sup>1066 was tested in two
preclinical models of neuropathic and visceral pain that have been extensively validated in rats. In the chronic constriction injury
model of neuropathic pain, a single oral administration of ANAVEX<sup>&#174;</sup>1066 dose-dependently restored the nociceptive
threshold in the affected paw to normal levels while leaving the contralateral healthy paw unchanged. Efficacy was rapid and remained
significant for two hours. In a model of visceral pain, chronic colonic hypersensitivity was induced by injection of an inflammatory
agent directly into the colon and a single oral administration of ANAVEX<sup>&#174;</sup>1066 returned the nociceptive threshold
to control levels in a dose-dependent manner. Companion studies in rats demonstrated the lack of any effects on normal gastrointestinal
transit with ANAVEX<sup>&#174;</sup>1066 and a favorable safety profile in a battery of behavioral measures.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 14; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->15<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>ANAVEX<sup>&#174;</sup>1037 </b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">ANAVEX<sup>&#174;</sup>1037 is designed for
the treatment of prostate and pancreatic cancer. It is a low molecular weight, synthetic compound exhibiting high affinity for
SIGMAR1 at nanomolar levels and moderate affinity for sigma-2 receptors and sodium channels at micromolar levels. In advanced pre-clinical
studies, this compound revealed antitumor potential. It has also been shown to selectively kill human cancer cells without affecting
normal/healthy cells and also to significantly suppress tumor growth in immune-deficient mice models. Scientific publications highlight
the possibility that these ligands may stop tumor growth and induce selective cell death in various tumor cell lines. Sigma receptors
are highly expressed in different tumor cell types. Binding by appropriate sigma-1 and/or sigma-2 ligands can induce selective
apoptosis. In addition, through tumor cell membrane reorganization and interactions with ion channels, we believe our drug candidates
may play an important role in inhibiting the processes of metastasis (spreading of cancer cells from the original site to other
parts of the body), angiogenesis (the formation of new blood vessels) and tumor cell proliferation.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">ANAVEX<sup>&#174;</sup>1037 is currently in
the pre-clinical and clinical testing stages of development, and there is no guarantee that the activity demonstrated in pre-clinical
models will be shown in human testing.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We continue to identify and initiate discussions
with potential strategic and commercial partners to most effectively advance our programs and increase stockholder value. Further,
we may acquire or develop new intellectual property and assign, license, or otherwise transfer our intellectual property to further
our goals.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Our Target Indications</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We are developing compounds with potential
application to two broad categories and several specific indications, including:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Central Nervous System Diseases</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Courier New, Courier, Monospace; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">Alzheimer&#8217;s
    disease &#8211; In 2023, an estimated 6.7 million Americans aged 65 and older are suffering from Alzheimer&#8217;s disease.
    The Alzheimer&#8217;s Association<sup>&#174;</sup> estimates that the annual number of new cases of Alzheimer&#8217;s and other
    dementias is projected to double by 2050. Medications on the market today treat only the symptoms of Alzheimer&#8217;s disease
    and do not have the ability to stop its onset or its progression. We believe that there is an urgent and unmet need for both
    a disease-modifying cure for Alzheimer&#8217;s disease as well as for better symptomatic treatments.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Courier New, Courier, Monospace; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">Parkinson&#8217;s
    disease &#8211; Parkinson&#8217;s disease is a progressive disease of the nervous system marked by tremors, muscular rigidity,
    and slow, imprecise movement. It is associated with degeneration of the basal ganglia of the brain and a deficiency of the
    neurotransmitter dopamine. Parkinson&#8217;s disease currently is estimated to afflict more than 10 million people worldwide,
    typically middle-aged and elderly people. The Parkinson&#8217;s disease market is expected to reach $11.5 billion by 2029,
    according to GlobalData.</span></td></tr>
</table>
<p style="font: 12pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Courier New, Courier, Monospace; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td><p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Rett
        syndrome &#8211; Rett syndrome is a rare X-linked genetic neurological and developmental disorder that affects the way
        the brain develops, including protein transcription, which is altered and as a result leads to severe disruptions in neuronal
        homeostasis. It is considered a rare, progressive neurodevelopmental disorder and is caused by a single mutation in the
        MECP2 gene. Because males have a different chromosome combination from females, boys who have the genetic MECP2 mutation
        are affected in devastating ways. Most of them die before birth or in early infancy. For females who survive infancy,
        Rett syndrome leads to severe impairments, affecting nearly every aspect of the child&#8217;s life; severe mental retardation,
        their ability to speak, walk and eat, sleeping problems, seizures and even the ability to breathe easily. Rett syndrome
        affects approximately 1 in every 10,000-15,000 females.</span></p>
        <p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>
        <p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p></td></tr>
</table>

<p style="margin: 0">&#160;</p>

<p style="margin: 0"></p>

<!-- Field: Page; Sequence: 15; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->16<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="margin: 0">&#160;</p>

<p style="margin: 0"></p>


<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 22.5pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Fragile
                                                                                                                                    X
                                                                                                                                    &#8211;
                                                                                                                                    Fragile
                                                                                                                                    X
                                                                                                                                    syndrome
                                                                                                                                    (FXS)
                                                                                                                                    is
                                                                                                                                    the
                                                                                                                                    most
                                                                                                                                    prevalent
                                                                                                                                    genetic
                                                                                                                                    form
                                                                                                                                    of
                                                                                                                                    intellectual
                                                                                                                                    disability
                                                                                                                                    and
                                                                                                                                    autism
                                                                                                                                    spectrum
                                                                                                                                    disorder,
                                                                                                                                    primarily
                                                                                                                                    affecting
                                                                                                                                    boys.
                                                                                                                                    As
                                                                                                                                    with
                                                                                                                                    most
                                                                                                                                    neurodevelopmental
                                                                                                                                    disorders,
                                                                                                                                    FXS
                                                                                                                                    is
                                                                                                                                    considered
                                                                                                                                    a
                                                                                                                                    condition
                                                                                                                                    of
                                                                                                                                    synaptic
                                                                                                                                    development
                                                                                                                                    and
                                                                                                                                    function.
                                                                                                                                    The
                                                                                                                                    disease
                                                                                                                                    has
                                                                                                                                    a
                                                                                                                                    range
                                                                                                                                    of
                                                                                                                                    clinical
                                                                                                                                    presentations
                                                                                                                                    depending
                                                                                                                                    on
                                                                                                                                    the
                                                                                                                                    specific
                                                                                                                                    genetic
                                                                                                                                    changes
                                                                                                                                    associated
                                                                                                                                    with
                                                                                                                                    an
                                                                                                                                    &#8220;expansion&#8221;
                                                                                                                                    of
                                                                                                                                    the
                                                                                                                                    FMR1
                                                                                                                                    gene.
                                                                                                                                    The
                                                                                                                                    disease
                                                                                                                                    is
                                                                                                                                    characterized
                                                                                                                                    by
                                                                                                                                    deficits
                                                                                                                                    in
                                                                                                                                    long-term
                                                                                                                                    potentiation
                                                                                                                                    and
                                                                                                                                    homeostatic
                                                                                                                                    plasticity.
                                                                                                                                    FXS
                                                                                                                                    has
                                                                                                                                    been
                                                                                                                                    detected
                                                                                                                                    in
                                                                                                                                    all
                                                                                                                                    populations
                                                                                                                                    and
                                                                                                                                    ethnic
                                                                                                                                    groups.
                                                                                                                                    Researchers
                                                                                                                                    do
                                                                                                                                    not
                                                                                                                                    know
                                                                                                                                    the
                                                                                                                                    exact
                                                                                                                                    number
                                                                                                                                    for
                                                                                                                                    how
                                                                                                                                    many
                                                                                                                                    Americans
                                                                                                                                    could
                                                                                                                                    have
                                                                                                                                    full
                                                                                                                                    mutation
                                                                                                                                    FXS.
                                                                                                                                    Studies
                                                                                                                                    estimate
                                                                                                                                    that
                                                                                                                                    the
                                                                                                                                    disease
                                                                                                                                    affects
                                                                                                                                    approximately
                                                                                                                                    1:4,000
                                                                                                                                    males
                                                                                                                                    and
                                                                                                                                    1:6,000-8,000
                                                                                                                                    females.
                                                                                                                                    Worldwide,
                                                                                                                                    more
                                                                                                                                    than
                                                                                                                                    1,400,000
                                                                                                                                    people
                                                                                                                                    could
                                                                                                                                    be
                                                                                                                                    affected
                                                                                                                                    by
                                                                                                                                    FXS.&#160;</span></td></tr></table>

<table cellspacing="0" cellpadding="0" style="font: 10pt Courier New, Courier, Monospace; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">Depression
    &#8211; Depression is a major cause of morbidity worldwide according to the World Health Organization. The global antidepressant
    drug market is projected to reach $21 Billion by 2030 according to Allied Market Research. Pharmaceutical treatment for depression
    has been historically dominated by blockbuster brands. However, the dominance of the leading brands is waning, largely due
    to an increase in the number of approvals for antidepressant drugs.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Courier New, Courier, Monospace; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">Epilepsy
    &#8211; Epilepsy is a common chronic neurological disorder characterized by recurrent unprovoked seizures. These seizures
    are transient signs and/or symptoms of abnormal, excessive or synchronous neuronal activity in the brain. According to the
    Centers for Disease Control and Prevention, in 2015 epilepsy affected 3.4 million Americans. Today, epilepsy is often controlled,
    but not cured, with medication that is categorized as older traditional anti-epileptic drugs and second generation anti-epileptic
    drugs. Because epilepsy afflicts sufferers in different ways, there is a need for drugs used in combination with both traditional
    anti-epileptic drugs and second generation anti-epileptic drugs.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">Neuropathic
    Pain &#8211; We define neuralgia, or neuropathic pain, as pain that is not related to activation of pain receptor cells in
    any part of the body. Neuralgia is more difficult to treat than some other types of pain because it does not respond well
    to normal pain medications. Special medications have become more specific to neuralgia and typically fall under the category
    of membrane stabilizing drugs or antidepressants.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">Cancer</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">Malignant
    Melanoma &#8211; Predominantly a skin cancer, malignant melanoma can also occur in melanocytes found in the bowel and the
    eye. Malignant melanoma accounts for a large majority of skin cancer deaths. The treatment includes surgical removal of the
    tumor, adjuvant treatment, chemo and immunotherapy, or radiation therapy. According to iHealthcareAnalyst, Inc. the worldwide
    malignant melanoma market is expected to grow to $7.5 billion by 2029.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">Prostate
    Cancer &#8211; Specific to men, prostate cancer is a form of cancer that develops in the prostate, a gland in the male reproductive
    system. Cancer cells may metastasize from the prostate to other parts of the body, particularly the bones and lymph nodes.
    Drug therapeutics for prostate cancer are expected to increase to nearly $10.1 billion by the end of 2030 according to Market
    Research Future.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">Pancreatic
    Cancer &#8211; Pancreatic cancer is a malignant neoplasm of the pancreas. In the United States, approximately 62,000 new cases
    of pancreatic cancer will be diagnosed this year and approximately 50,000 patients will die as a result of their cancer, according
    to the American Cancer Society. Sales predictions by Market Data Forecast predict that the market for the global pharmaceutical
    treatment of pancreatic cancer will increase to $3.7 billion by 2027.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 16; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->17<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Competition</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The drug discovery and development industry
is very competitive, characterized by rapid advancements in technology, where protection of proprietary advancements is essential.
Any product candidates that we may successfully develop and commercialize, may compete with existing therapies, or new therapies
that may become available in the future. Our commercial opportunities could be reduced or eliminated if our competitors develop
and commercialize products that are more effective, have fewer side effects, are more convenient or are less expensive than any
products that we may develop.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">We believe our approach to the treatment
of Alzheimer&#8217;s disease and other CNS diseases differs from our competitors - our platform may offer a disease-modifying approach
in neurodegenerative and neurodevelopmental diseases by activation of SIGMAR1. In our preclinical studies, when activated by SIGMAR1
agonists, such as ANAVEX<sup>&#174;</sup>2-73, SIGMAR1 demonstrated reduced cellular stress before and after RNA gene transcription.
Our studies confirm the potential existence of a predictive biomarker of response established through SIGMAR1 mRNA expression that
could be used in future clinical trials. Because of its role in maintaining neuronal homeostasis, we believe sigma receptors show
significant promise as viable targets for therapeutic molecules in an effort to treat Alzheimer&#8217;s disease and other CNS diseases
and disorders, including Parkinson&#8217;s disease and Rett syndrome, by restoring healthy gene expression.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">At this time, our competitors are primarily
other biomedical development companies that are aiming to discover and develop compounds to be used in the treatment of Alzheimer&#8217;s
disease and other CNS diseases, and those companies already doing so. We also face competition from academic institutions and government
agencies, both in the United States and abroad.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Our competitors may have significantly
greater financial resources, an established presence in the market, expertise in research and development, manufacturing, preclinical
and clinical testing, may be in the process of obtaining regulatory approvals and marketing of approved products. These competitors
also compete with us in recruiting and retaining qualified scientific and technical personnel, establishing clinical trial sites
and patient registration for clinical trials, as well as in acquiring or developing technologies complementary to, or necessary
for, our programs. Smaller or early-stage companies may also prove to be significant competitors, particularly through collaborative
arrangements with large and established companies.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">For additional discussion of the risks
related to competition, see Item 1A &#8220;Risk Factors.&#8221;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Patents, Trademarks and Intellectual
Property </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We hold ownership or exclusive rights to twenty-two
U.S. patents, twenty-three U.S. patent applications, and various PCT or ex-U.S. patent applications relating to our drug candidates,
methods associated therewith, and to our research programs.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We own one issued U.S. patent entitled &#8220;ANAVEX<sup>&#174;</sup>2-73
and certain anticholinesterase inhibitors composition and method for neuroprotection&#8221; claims a composition of matter of ANAVEX<sup>&#174;</sup>2-73
directed to a novel and synergistic neuroprotective compound combined with donepezil and other cholinesterase inhibitors. This
patent is expected to expire in June 2034, absent any patent term extension for regulatory delays. We own one issued U.S. patent
entitled &#8220;A2-73 crystalline polymorph compositions of matter and methods of use thereof&#8221;. It claims crystals of A2-73
freebase or its fumarate salt, dosage forms and pharmaceutical formulations. This patent is expected to expire in July 2039, absent
any patent term extension for regulatory delays. We own four issued U.S. patents each with claims directed to crystalline forms
of ANAVEX<sup>&#174;</sup>2-73. The first of these four patents claims crystalline forms of ANAVEX<sup>&#174;</sup>2-73, dosage forms
and compositions containing crystalline ANAVEX<sup>&#174;</sup>2-73, and methods of treatment for Alzheimer&#8217;s disease using
them. This patent is expected to expire in July 2036, absent any patent term extension for regulatory delays. The second of these
four patents claims pharmaceutical compositions containing a crystalline form of ANAVEX<sup>&#174;</sup>2-73, and methods of treatment
for Alzheimer&#8217;s disease using the compositions. This patent is expected to expire in June 2036, absent any patent term extension
for</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 17; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->18<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;<br />
regulatory delays. The third of these four patents claims pharmaceutical compositions containing a crystalline form of ANAVEX<sup>&#174;</sup>2-73,
and methods of treatment for Alzheimer&#8217;s disease using the compositions. This patent is expected to expire in June 2036,
absent any patent term extension for regulatory delays. The fourth of these four patents claims method of making certain crystalline
forms ANAVEX<sup>&#174;</sup>2-73. This patent is expected to expire in October 2036, absent any patent term extension for regulatory
delays. We also own three issued U.S. patents for seizure treatment. The first of these three patents claims methods and dosage
forms for treating seizures, the dosage forms containing a low-dose anti-epilepsy drug combined with either: (i) ANAVEX<sup>&#174;</sup>2-73
and its active metabolite ANAVEX<sup>&#174;</sup>19-144; or (ii) ANAVEX<sup>&#174;</sup>19-144. The second of these three patents
further claims a combination seizure treatment involving administration of an anti-epilepsy drug combined with (i) ANAVEX<sup>&#174;</sup>19-144,
or (ii) ANAVEX 19-144<sup>&#174;</sup> and ANAVEX 2-73<sup>&#174;</sup>. The third of these three patents claims a dosage form for
seizure reduction, comprising (i) ANAVEX19-144<sup>&#174;</sup>, (ii) ANAVEX 2-73<sup>&#174;</sup>, or (iii) a combination of ANAVEX19-144<sup>&#174;
</sup>and ANAVEX 2-73<sup>&#174;</sup>; and optionally further comprising a low-dose anti-epilepsy drug. All three patents are
expected to expire in October 2035, absent any patent term extension for regulatory delays. We also own three issued U.S. patents
with claims directed to treating neurodevelopmental disorders. These patents claim methods for treating a neurodevelopmental disorder,
multiple sclerosis, or their related biochemical and functional abnormalities by administering ANAVEX<sup>&#174;</sup>2-73, ANAVEX<sup>&#174;</sup>19-144,
and/or ANAVEX<sup>&#174;</sup>1-41 (another sigma receptor ligand similar to ANAVEX<sup>&#174;</sup>2-73), or compositions thereof.
All three patents are expected to expire in January 2037, absent any patent term extension for regulatory delays. In addition,
we own one issued U.S. Patent with claims directed to methods of treating melanoma with a compound related to ANAVEX<sup>&#174;</sup>2-73.
This patent is expected to expire in February 2030, absent any patent term extension for regulatory delays. We also own an issued
U.S. patent that claims crystalline forms of ANAVEX<sup>&#174;</sup>19-144, dosage forms and compositions containing the crystalline
forms of ANAVEX<sup>&#174;</sup>19-144, and methods of treatment for Alzheimer&#8217;s disease. This patent is expected to expire
in July 2036, absent any patent term extension for regulatory delays. Further, we own one issued U.S. Patent with claims directed
to methods of treating cardiac dysfunction with ANAVEX<sup>&#174;</sup>2-73. This patent is expected to expire in July 2038, absent
any patent term extension for regulatory delays. Additionally, we own one issued U.S. Patent with claims directed to methods of
treating insomnia or anxiety with ANAVEX<sup>&#174;</sup>2-73, ANAVEX<sup>&#174;</sup>19-144, and/or ANAVEX<sup>&#174;</sup>1-41.
This patent is expected to expire in September 2038, absent any patent term extension for regulatory delays. Further, we own one
issued U.S. Patent with claims directed to a method of treating systolic hypertension using ANAVEX<sup>&#174;</sup>2-73. This patent
is expected to expire in July 2039, absent any patent term extension for regulatory delays. Additionally, we own one issued U.S.
Patent with claims directed to pharmaceutical dosage forms of (-) enantiomer of ANAVEX<sup>&#174;</sup>2-73. This patent is expected
to expire in July 2036, absent any patent term extension for regulatory delays.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We also own two issued U.S. patents related
to ANAVEX<sup>&#174;</sup>1066. The first of these two patents claims methods for treating or preventing pain using (+) ANAVEX<sup>&#174;</sup>1066
isomer. The second patent claims methods for treating or preventing pain using (-) ANAVEX<sup>&#174;</sup>1066 isomer. Both patents
are expected to expire in November 2036, absent any patent term extension for regulatory delays.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">For ANAVEX<sup>&#174;</sup>2-73, ANAVEX<sup>&#174;</sup>19-144,
ANAVEX<sup>&#174;</sup>1-41, and ANAVEX<sup>&#174;</sup>1066, we also have granted or pending applications in Australia, Canada,
China, Europe, Japan, and Hong Kong, which are expected to expire after 2035.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">With regard to ANAVEX<sup>&#174;</sup>3-71,
we own exclusive rights to two issued U.S. patents with claims respectively directed to the ANAVEX<sup>&#174;</sup>3-71 compound
and methods of treating various diseases including Alzheimer&#8217;s with the same. These patents are expected to expire in April
2030, and January 2030, respectively, absent any patent term extension for regulatory delays. We also own exclusive rights to related
patents or applications that are granted or pending in Australia, Canada, China, Europe, Japan, Korea, New Zealand, Russia, and
South Africa, which are expected to expire in January 2030.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We also own other patent applications directed
to enantiomers, crystals, formulations, uses, and patient selection methods that may provide additional protection for one or more
of our product candidates.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We regard patents and other intellectual property
rights as corporate assets. Accordingly, we attempt to optimize the value of intellectual property in developing our business strategy
including the selective development, protection, and exploitation of our intellectual property rights. In addition to filings made
with intellectual property authorities, we protect our intellectual property and confidential information by means of carefully
considered processes of communication and the sharing of information, and by the use of confidentiality and non-disclosure agreements
and provisions for the same in contractor&#8217;s agreements. While no agreement offers absolute protection, such agreements provide
some form of recourse in the event of disclosure, or anticipated disclosure.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 18; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->19<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="background-color: white">Our
intellectual property position, like that of many biomedical companies, is uncertain and involves complex legal and technical questions
for which important legal principles are unresolved. For more information regarding challenges to our existing or future patents,
see &#8220;Risk Factors&#8221; in Part I, Item 1A of this Annual Report on Form 10-K.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><b><i>Government regulation </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Government authorities in the United States,
at the federal, state and local levels, and other countries extensively regulate, among other things, the research, development,
testing, manufacture, quality control, approval, labeling, packaging, storage, record-keeping, promotion, advertising, distribution,
marketing and export and import of products such as those we are developing. A new drug must be approved by the FDA through the
NDA or ANDA process before it may be legally marketed in the United States. We are subject to various government regulations in
connection with the development of our pipeline.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>U.S. Drug Development and Regulation </i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In the United States, the FDA regulates drugs
under the Federal Food, Drug, and Cosmetic Act and its implementing regulations (&#8220;FDCA&#8221;). The process of obtaining
regulatory approvals and the subsequent compliance with appropriate federal, state, local and foreign statutes and regulations
require the expenditure of substantial time and financial resources. Failure to comply with the applicable U.S. requirements at
any time during the product development process, approval process or post approval may subject an applicant to administrative or
judicial sanctions. These sanctions could include the FDA&#8217;s refusal to approve pending applications, withdrawal of an approval,
import refusal, a clinical hold, warning letters, product recalls, product seizures, total or partial suspension of production
or distribution, injunctions, fines, refusals of government contracts, restitution, disgorgement or civil or criminal penalties.
Any agency or judicial enforcement action could have a material adverse effect on us.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Once a drug candidate is identified for development,
it enters the preclinical testing stage and an Investigational New Drug Application (&#8220;IND&#8221;) may be opened for the regulatory
development of the product. Preclinical tests include laboratory evaluations of product chemistry, toxicity and formulation, as
well as other preclinical studies. An IND sponsor must submit the results of the preclinical tests, together with manufacturing
information and analytical data, to the FDA as part of the IND to conduct clinical trials. The sponsor must also include a protocol
detailing, among other things, the objectives of the clinical trials, the parameters to be used in monitoring the safety of the
trial, and the effectiveness criteria to be evaluated should the trial include an efficacy evaluation. Some preclinical testing
may continue even after the IND is filed. The IND automatically becomes effective thirty (30) days after receipt by the FDA, unless
the FDA, within the 30-day time period, places the clinical trial on a clinical hold. Clinical holds also may be imposed by the
FDA at any time before or during clinical trials due to safety concerns about ongoing or proposed clinical trials or non-compliance
with specific FDA requirements, and the trials may not begin or continue until the FDA notifies the sponsor that the hold has been
lifted.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">All clinical trials must be conducted under
the supervision of one or more qualified investigators in accordance with FDA good clinical practice (&#8220;GCP&#8221;) requirements,
which include a requirement that all research subjects provide their informed consent in writing for their participation in any
clinical trial. Clinical trials must be conducted under protocols detailing the objectives of the trial, dosing procedures, subject
selection inclusion and exclusion criteria and the safety and/or effectiveness criteria to be evaluated. Each protocol must be
submitted to the FDA as part of the IND, and timely safety reports must be submitted to the FDA and the investigators for serious
and unexpected adverse events. An Institutional Review Board (&#8220;IRB&#8221;) at each institution participating in the clinical
trial must review and approve each protocol before a clinical trial may commence at the institution and must also approve the information
regarding the trial as well as the informed consent form that must be provided to each trial participant or his or her legal representative,
monitor the study until completed and otherwise comply with all applicable IRB regulations.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 19; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->20<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Human clinical trials are typically conducted
in three sequential phases that may overlap or be combined in certain cases:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Phase 1: The compound is initially introduced
into healthy human subjects and tested for safety, dosage tolerance, absorption, metabolism, distribution and excretion and, if
possible, to gain an early indication of its effectiveness. In most cases, initial Phase 1 clinical trials are conducted with healthy
volunteers. However, where the compound being evaluated is for the treatment of severe or life-threatening diseases, such as cancer,
and especially when the product may be too toxic to ethically administer to healthy volunteers, the initial human testing may be
conducted on patients with the target disease or condition. Sponsors sometimes subdivide their Phase 1 clinical trials into Phase
1a and Phase 1b clinical trials. Phase 1b clinical trials are typically aimed at confirming dosage, PK and safety in a larger number
of patients. Some Phase 1b clinical trials evaluate biomarkers or surrogate markers that may be associated with efficacy in patients
with specific types of diseases or conditions.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Phase 2: This phase involves clinical trials
in a limited patient population to identify possible adverse effects and safety risks, to preliminarily evaluate the efficacy of
the product for specific targeted diseases or conditions and to confirm dosage tolerance and appropriate dosage.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Phase 3: Phase 3 clinical trials are undertaken
to further evaluate dosage, clinical efficacy and safety in an expanded patient population, generally at geographically dispersed
clinical trial sites. These clinical trials, often referred to as &#8220;pivotal&#8221; or &#8220;confirmatory&#8221; clinical
trials, are intended to establish the overall risk-benefit ratio of the compound and provide, if appropriate, an adequate basis
for product approval and labeling.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The FDA or the sponsor may suspend a clinical
trial at any time on various grounds, including any finding that the research subjects or patients are being exposed to an unacceptable
health risk. Similarly, an IRB can suspend or terminate approval of a clinical trial at its institution if the clinical trial is
not being conducted in accordance with the IRB&#8217;s requirements or if the drug has been associated with unexpected, serious
harm to study subjects. In addition, clinical trials may be overseen by an independent group of qualified experts organized by
the sponsor, known as a data safety monitoring board or committee. Depending on its charter, this board or committee may determine
whether a trial may move forward at designated check points based on access to certain data from the trial.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Phase 4: Phase 4 or post-approval trials may
also be conducted after a drug receives initial marketing approval. These trials, often referred to as &#8220;Phase 4&#8221; trials,
are used to gain additional experience from the treatment of patients in the intended therapeutic indication. In certain instances,
the FDA may mandate the performance of such clinical trials as a condition of approval of continued marketing of the product.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">During the development of a new drug, sponsors
are given several opportunities to meet with the FDA. These meetings can provide an opportunity for the sponsor to share information
about the progress of the application or clinical trials, for the FDA to provide advice, and for the sponsor and the FDA to reach
agreement on the next phase of development. These meetings may occur prior to the submission of an IND, at the end of Phase 2 clinical
trials, or before an NDA is ultimately submitted. Sponsors typically use the meetings at the end of the Phase 2 trials to discuss
Phase 2 clinical results and present plans for the pivotal Phase 3 clinical trials that they believe will support approval of the
new drug. Meetings at other times may be made upon request and are subject to approval by the FDA.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Concurrent with clinical trials, companies
typically complete additional, animal or other non-clinical studies, develop additional information about the chemistry and physicochemical
characteristics of the drug, and finalize a process for manufacturing the product in commercial quantities in accordance with the
FDA&#8217;s current Good Manufacturing Practices (&#8220;cGMP&#8221;) requirements. The manufacturing process must consistently
produce quality batches of the drug and, among other things, the manufacturer must develop methods for testing the identity, strength,
quality and purity of the final drug. In addition, appropriate packaging must be selected and tested, and stability studies must
be conducted to demonstrate the effectiveness of the packaging and that the compound does not undergo unacceptable deterioration
over its shelf life.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 20; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->21<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">While the IND is active, progress reports summarizing
the results of ongoing clinical trials and nonclinical studies performed since the last progress report must be submitted on at
least an annual basis to the FDA, and written IND safety reports must be submitted to the FDA and investigators for serious and
unexpected adverse events, findings from other studies suggesting a significant risk to humans exposed to the same or similar drugs,
findings from animal or in vitro testing suggesting a significant risk to humans, and any clinically important, increased incidence
of a serious adverse reaction compared to that listed in the protocol or investigator brochure.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">There are also requirements governing the submission
of certain clinical trials and completed trial results to public registries. Sponsors of certain clinical trials of FDA-regulated
products are required to register and disclose specified clinical trial registration and results information, which is made publicly
available at www.clinicaltrials.gov. Failure to properly report clinical trial results can result in civil monetary penalties.
Disclosure of clinical trial results can often be delayed until the new product or new indication being studied has been approved.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>U.S. review and approval process </i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The results of product development, preclinical
and other non-clinical studies and clinical trials, along with descriptions of the manufacturing process, analytical tests conducted
on the chemistry of the drug, proposed labeling and other relevant information are submitted to the FDA as part of a New Drug Application
(&#8220;NDA&#8221;). The submission of an NDA is subject to the payment of substantial user fees; a waiver of which may be obtained
under certain limited circumstances.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The FDA reviews NDAs to determine, among other
things, whether the product is safe and effective for its intended use and whether it is manufactured in a cGMP-compliant manner,
which will assure and preserve the product&#8217;s identity, strength, quality and purity. Under the Prescription Drug User Fee
Act (&#8220;PDUFA&#8221;), the FDA has a goal of ten months from the date of &#8220;filing&#8221; of a standard, completed NDA
for a new molecular entity to review and act on the submission. This review typically takes twelve months from the date the NDA
is submitted to the FDA because the FDA has approximately two months to make a &#8220;filing&#8221; decision after the application
is submitted. The FDA conducts a preliminary review of all NDAs within the first sixty days after submission, before accepting
them for filing, to determine whether they are sufficiently complete to permit substantive review. The FDA may request additional
information rather than accept an NDA for filing. In this event, the NDA must be resubmitted with the additional information. The
resubmitted application also is subject to review before the FDA accepts it for filing.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The FDA may refer an application for a new
drug to an advisory committee. An advisory committee is a panel of independent experts, including clinicians and other scientific
experts, that reviews, evaluates and provides a recommendation as to whether and under what conditions the application should be
approved. The FDA is not bound by the recommendations of such an advisory committee, but it considers advisory committee recommendations
carefully when making decisions.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Before approving an NDA, the FDA will also
inspect the facility where the product is manufactured. The FDA will not approve an application unless it determines that the manufacturing
processes and facilities are in compliance with cGMP requirements and are adequate to assure consistent production of the product
within required specifications. Before approving an NDA, the FDA may also inspect one or more clinical trial sites to assure compliance
with GCP requirements and inspect the clinical trial records.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">After the FDA evaluates an NDA, it will issue
an approval letter or a Complete Response Letter. A Complete Response Letter indicates that the review cycle of the application
is complete, and the application will not be approved in its present form. A Complete Response Letter usually describes the specific
deficiencies in the NDA identified by the FDA and may require additional clinical data, such as an additional pivotal Phase 3 trial
or other significant and time-consuming requirements related to clinical trials, nonclinical studies or product manufacturing.
If a Complete Response Letter is issued, the sponsor must resubmit the NDA, addressing all of the deficiencies identified in the
letter, or withdraw the application. Even if such data and information are submitted, the FDA may decide that the NDA does not
satisfy the criteria for approval. An approval letter authorizes commercial marketing of the drug with prescribing information
for specific indications.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 21; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->22<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Pediatric Research Equity Act (&#8220;PREA&#8221;),
requires IND sponsors to conduct pediatric clinical trials for most drugs, for a new active ingredient, new indication, new dosage
form, new dosing regimen or new route of administration. Under PREA, original NDAs and supplements must contain a pediatric assessment
unless the sponsor has received a deferral or waiver. The required assessment must evaluate the safety and effectiveness of the
product for the claimed indications in all relevant pediatric subpopulations and support dosing and administration for each pediatric
subpopulation for which the product is safe and effective. The sponsor or the FDA may request a deferral of pediatric clinical
trials for some or all of the pediatric subpopulations. A deferral may be granted for several reasons, including a finding that
the drug is ready for approval for use in adults before pediatric clinical trials are complete or that additional safety or effectiveness
data needs to be collected before the pediatric clinical trials begin. The FDA must send a non-compliance letter to any sponsor
that fails to submit the required assessment, keep a deferral current or fails to submit a request for approval of a pediatric
formulation.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If a drug receives FDA approval, the approval
may be limited to specific diseases and dosages, which could restrict the commercial value of the product. In addition, the FDA
may require testing and surveillance programs to monitor the safety of approved products which have been commercialized and may
require a sponsor to conduct post-marketing clinical trials (Phase 4 clinical trials), which are designed to further assess a drug&#8217;s
safety and effectiveness after NDA approval. The FDA may also place other conditions on approval, including a requirement for a
risk evaluation and mitigation strategy (&#8220;REMS&#8221;) to assure the safe use of the drug. If the FDA concludes a REMS is
needed, the sponsor of the NDA must submit a proposed REMS. The FDA will not approve the NDA without an approved REMS, if required.
A REMS could include medication guides, physician communication plans or elements to assure safe use, such as restricted distribution
methods, patient registries and other risk minimization tools. Any of these limitations on approval or marketing could restrict
the commercial promotion, distribution, prescribing or dispensing of products. Marketing approval may be withdrawn for non-compliance
with REMS or other regulatory requirements, or if problems occur following initial marketing.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>Post-approval requirements </i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Once an approval is granted, the FDA may withdraw
the approval if compliance with regulatory standards is not maintained or if problems occur after the drug reaches the market.
Later discovery of previously unknown problems with a drug may result in restrictions on the drug or even complete withdrawal of
the drug from the market. After approval, some types of changes to the approved drug, such as adding new indications, certain manufacturing
changes and additional labeling claims, are subject to further FDA review and approval. Manufacturers and other entities involved
in the manufacture and distribution of approved drugs are required to register their establishments with the FDA and certain state
agencies and are subject to periodic unannounced inspections by the FDA and certain state agencies for compliance with cGMP regulations
and other laws and regulations.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Any drug product manufactured or distributed
by us pursuant to FDA approval will be subject to continuing regulation by the FDA, including, among other things, record-keeping
requirements, reporting of adverse experiences with the drug, providing the FDA with updated safety and efficacy information, drug
sampling and distribution requirements, complying with certain electronic records and signature requirements, and complying with
FDA promotion and advertising requirements. FDA strictly regulates labeling, advertising, promotion and other types of information
regarding approved drugs that are placed on the market, and imposes requirements and restrictions on drug manufacturers, such as
those related to direct-to-consumer advertising, the prohibition on promoting products for uses or in patient populations that
are not described in the product&#8217;s approved labeling (known as &#8220;off-label use&#8221;), industry-sponsored scientific
and educational activities, and promotional activities involving the internet. Discovery of previously unknown problems or the
failure to comply with the applicable regulatory requirements may result in restrictions on the marketing of a product for a certain
indication or withdrawal of the product from the market as well as possible civil or criminal sanctions. Failure to comply with
the applicable governmental requirements at any time during the product development process, approval process or after approval,
may subject an applicant or manufacturer to administrative or judicial civil or criminal sanctions and adverse publicity. The FDA
sanctions could include refusal to approve pending applications, withdrawal of an approval, clinical holds on post-marketing clinical
trials, enforcement letters, import refusals, product recalls, product seizures, total or partial suspension of production or distribution,
injunctions, fines, refusals of government contracts, mandated corrective advertising or communications with doctors, debarment,
restitution, disgorgement of profits, or civil or criminal penalties.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 22; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->23<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>Expedited development and review programs
</i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The FDA has a fast track designation program
that is intended to expedite or facilitate the process for reviewing new drug products that meet certain criteria. Specifically,
new drugs are eligible for fast track designation if they are intended to treat a serious or life-threatening disease or condition
and demonstrate the potential to address unmet medical needs for the disease or condition. With regard to a fast track product,
the FDA may consider for review sections of the NDA on a rolling basis before the complete application is submitted, if the sponsor
provides a schedule for the submission of the sections of the NDA, the FDA agrees to accept sections of the NDA and determines
that the schedule is acceptable, and the sponsor pays any required user fees upon submission of the first section of the NDA.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Any product submitted to the FDA for approval,
including a product with a fast track designation, may also be eligible for other types of FDA programs intended to expedite development
and review, such as priority review and accelerated approval.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">A product is eligible for priority review if
it is intended to treat a serious condition, and if approved, would provide a significant improvement in safety or efficacy compared
to currently marketed products. The FDA will attempt to direct additional resources to the evaluation of an application for a new
drug designated for priority review in an effort to facilitate the review. The FDA endeavors to review applications with priority
review designations within six months of the filing date, as compared to ten months for review of NDAs under its current PDUFA
review goals.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In addition, a product may be eligible for
accelerated approval. Drugs intended to treat serious or life-threatening diseases or conditions may be eligible for accelerated
approval upon a determination that the product has an effect on a surrogate endpoint that is reasonably likely to predict a clinical
benefit, or on a clinical endpoint that can be measured earlier than irreversible morbidity or mortality, that is reasonably likely
to predict an effect on irreversible morbidity or mortality or other clinical benefit, taking into account the severity, rarity,
or prevalence of the condition and the availability or lack of alternative treatments. As a condition of approval, the FDA may
require that a sponsor of a drug receiving accelerated approval perform adequate and well-controlled post-marketing clinical trials.
Drugs receiving accelerated approval may be subject to expedited withdrawal procedures if the sponsor fails to conduct the required
post-marketing trials or if such trials fail to verify the predicted clinical benefit. In addition, the FDA currently requires
as a condition for accelerated approval pre-approval of promotional materials, which could adversely impact the timing of the commercial
launch of the product.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Food and Drug Administration Safety and
Innovation Act (&#8220;FDASIA&#8221;) established a category of drugs referred to as &#8220;breakthrough therapies&#8221; that
may be eligible to receive breakthrough therapy designation. A sponsor may seek FDA designation of a compound as a &#8220;breakthrough
therapy&#8221; if the product is intended, alone or in combination with one or more other products, to treat a serious or life-threatening
disease or condition and preliminary clinical evidence indicates that the product may demonstrate substantial improvement over
existing therapies on one or more clinically significant endpoints, such as substantial treatment effects observed early in clinical
development. The designation includes all of the fast track program features, as well as more intensive FDA interaction and guidance.
The breakthrough therapy designation is a distinct status from both accelerated approval and priority review, which can also be
granted to the same drug if relevant criteria are met. If a product is designated as breakthrough therapy, the FDA will work to
expedite the development and review of such drug.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Fast track designation, priority review and
breakthrough therapy designation do not change the standards for approval but may expedite the development or approval process.
However, even if a product qualifies for one or more of these programs, the FDA may later decide that the product no longer meets
the conditions for qualification or decide that the time period for FDA review or approval will not be shortened.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 23; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->24<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>Orphan drug designation </i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Under the Orphan Drug Act, the FDA may grant
orphan designation to a drug intended to treat a rare disease or condition, which is a disease or condition that affects fewer
than 200,000 individuals in the United States or, if it affects more than 200,000 individuals in the United States, there is no
reasonable expectation that the cost of developing and making a drug product available in the United States for this type of disease
or condition will be recovered from sales of the product. Orphan designation must be requested before an NDA is submitted. After
the FDA grants orphan designation, the identity of the therapeutic agent and its potential orphan use are publicly disclosed by
the FDA. Orphan designation does not convey any advantage in or shorten the duration of the regulatory review and approval process.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If a product that has orphan designation subsequently
receives the first FDA approval for the disease or condition for which it has such designation, the product is entitled to orphan
product exclusivity, which means that the FDA may not approve any other applications to market the same drug for the same indication
for seven years, except in limited circumstances, such as a showing of clinical superiority to the product with orphan exclusivity
or inability to manufacture the product in sufficient quantities. The designation of such drug also entitles a party to financial
incentives such as opportunities for grant funding towards clinical trial costs, tax advantages and user-fee waivers. However,
competitors may receive approval of different products for the indication for which the orphan product has exclusivity or obtain
approval for the same product but for a different indication for which the orphan product has exclusivity. Orphan exclusivity also
could block the approval of one of our compounds for seven years if our compound is determined to be contained within the competitor&#8217;s
product for the same indication or disease, or if a competitor obtains approval of the same drug as defined by the FDA. In addition,
if an orphan designated product receives marketing approval for an indication broader than what is designated, it may not be entitled
to orphan exclusivity.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>Abbreviated New Drug Applications, 505(b)(2)
Applications, and Marketing exclusivity </i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In seeking approval for a drug through an NDA,
applicants are required to list with the FDA each patent with claims that cover the applicant&#8217;s drug or an approved method
of use of the drug. Upon approval of a drug, each of the patents listed in the application for the drug is then published in the
FDA&#8217;s Approved Drug Products with Therapeutic Equivalence Evaluations, commonly known as the &#8220;Orange Book.&#8221; Drugs
listed in the Orange Book can, in turn, be cited by competitors in support of approval of an Abbreviated New Drug Application,
or ANDA, or a 505(b)(2)&#160;application. In this case, the original NDA (the&#160;so-called&#160;pioneer drug) is known as the
&#8220;listed&#8221; drug or &#8220;reference-listed&#8221; drug. An ANDA provides for marketing of a drug that has the same active
ingredient and the same strength, route of administration and dosage form as the listed drug and has been shown through testing
to be bioequivalent to the listed drug or receives a waiver from bioequivalence testing. ANDA applicants are generally not required
to conduct or submit results of preclinical or clinical tests to prove the safety or effectiveness of their drug, other than the
requirement for bioequivalence testing. Drugs approved in this way are considered therapeutically equivalent, and are commonly
referred to as &#8220;generic equivalents&#8221; to the listed drug. These drugs then generally can be substituted by pharmacists
under prescriptions written for the original listed drug.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">A 505(b)(2) application is a type of NDA that
relies, in part, upon data the applicant does not own and to which it does not have a right of reference. Such applications often
are submitted for changes to previously approved drug products, and rely on the FDA&#8217;s prior findings of safety and effectiveness
for a third party&#8217;s NDA to abbreviate the showings the sponsor of the 505(b)(2) application must make to establish that its
product is safe and effective.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 24; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->25<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The ANDA or 505(b)(2)&#160;applicant is required
to certify to FDA concerning any patents listed for the referenced approved drug in FDA&#8217;s Orange Book. Specifically, for
each listed patent, the applicant must certify that: (1)&#160;the required patent information has not been filed; (2)&#160;the
listed patent has expired; (3)&#160;the listed patent has not expired but will expire on a particular date and approval is sought
after patent expiration; or (4)&#160;the listed patent is invalid, unenforceable or will not be infringed by the new drug. A certification
that the new drug will not infringe the already approved drug&#8217;s listed patents or that such patents are invalid or unenforceable
is called a Paragraph IV certification. If the ANDA or 505(b)(2)&#160;applicant does not include a Paragraph IV certification,
the ANDA or 505(b)(2)&#160;application will not be approved until all of the listed patents claiming the referenced drug have expired,
except for any listed patents that only apply to uses of the drug not being sought by the ANDA or 505(b)(2)&#160;applicant.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If the ANDA or 505(b)(2)&#160;applicant has
made a Paragraph IV certification, the applicant must also send notice of a Paragraph IV Notice Letter to the NDA and patent holders
once the ANDA or 505(b)(2)&#160;application has been accepted for filing by FDA. The NDA and patent holders may then initiate a
patent infringement lawsuit in response to the notice of the Paragraph IV Notice Letter. The filing of a patent infringement lawsuit
within 45&#160;days of the receipt of notice of a Paragraph IV Notice Letter automatically prevents FDA from approving the ANDA
until the earlier of 30&#160;months, expiration of the patent, settlement of the lawsuit, modification by a court or a decision
in the infringement case that is favorable to the ANDA or 505(b)(2)&#160;applicant. As discussed below, the ANDA or 505(b)(2)&#160;application
also will not be approved until any applicable&#160;non-patent&#160;exclusivity listed in the Orange Book for the reference-listed
drug has expired.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Market exclusivity provisions under the FDCA
can delay the submission or approval of certain marketing applications. The FDCA provides a five-year period of non-patent marketing
exclusivity within the United States to the first applicant to obtain approval of an NDA for a new chemical entity. A drug is a
new chemical entity if the FDA has not previously approved any other new drug containing the same active moiety, which is the molecule
or ion responsible for the action of the drug substance. During the exclusivity period, the FDA may not approve or even accept
for review an abbreviated new drug application (&#8220;ANDA&#8221;), or an NDA submitted under Section 505(b)(2) (a &#8220;505(b)(2)
NDA&#8221;), submitted by another company for another drug containing the same active moiety, regardless of whether the drug is
intended for the same indication as the original innovative drug or for another indication, where the applicant does not own or
have a legal right of reference to all the data required for approval. However, an application may be submitted after four years
if it contains a certification of patent invalidity or non-infringement to one of the patents listed with the FDA by the innovator
NDA holder.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The FDCA alternatively provides three years
of marketing exclusivity for an NDA, or supplement to an existing NDA, if new clinical investigations, other than bioavailability
studies, that were conducted or sponsored by the applicant are deemed by the FDA to be essential to the approval of the application,
for example new indications, dosages or strengths of an existing drug. This three-year exclusivity covers only the modification
for which the drug received approval on the basis of the new clinical investigations and does not prohibit the FDA from approving
ANDAs or 505(b)(2) NDAs for drugs containing the active ingredient for the original indication or condition of use. Five-year and
three-year exclusivity will not delay the submission or approval of a full NDA. However, an applicant submitting a full NDA would
be required to conduct or obtain a right of reference to all of the preclinical studies and adequate and well-controlled clinical
trials necessary to demonstrate safety and effectiveness.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Pediatric exclusivity is another type of marketing
exclusivity available in the United States. Pediatric exclusivity provides for an additional six months of marketing exclusivity
attached to another period of exclusivity if a sponsor conducts clinical trials in children in response to a written request from
the FDA. The issuance of a written request does not require the sponsor to undertake the described clinical trials. In addition,
orphan drug exclusivity, as described above, may offer a seven-year period of marketing exclusivity, except in certain circumstances.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 25; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->26<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>United States Patent Term Restoration</i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Depending upon the timing, duration and specifics
of FDA approval of our future product candidates, some of our United States patents may be eligible for limited patent term extension
under the Drug Price Competition and Patent Term Restoration Act of 1984, commonly referred to as the Hatch-Waxman Amendments.
The Hatch-Waxman Amendments permit restoration of the patent term of up to five years as compensation for patent term lost during
the FDA regulatory review process for a drug that has not been previously approved for commercial marketing. Patent-term restoration,
however, cannot extend the remaining term of a patent beyond a total of 14 years from the product&#8217;s approval date and only
those claims covering such approved drug product, a method for using it or a method for manufacturing it may be extended. The patent-term
restoration period is generally&#160;one-half&#160;the time between the effective date of an IND and the submission date of an
NDA plus the time between the submission date of an NDA and the approval of that application, except that the review period is
reduced by any time during which the applicant failed to exercise due diligence. Only one patent applicable to an approved drug
is eligible for the extension and the application for the extension must be submitted prior to the expiration of the patent. The
U.S. Patent and Trademark Office, in consultation with the FDA, reviews and approves the application for any patent term extension
or restoration. In the future, we may apply for restoration of patent term for our currently owned or licensed patents to add patent
life beyond its current expiration date, depending on the expected length of the clinical trials and other factors involved in
the filing of the relevant NDA.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>Foreign Sales</i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Sales outside the United States of potential
drug compounds we develop will also be subject to foreign regulatory requirements governing human clinical trials and marketing
for drugs. The requirements vary widely from country to country, but typically the registration and approval process takes several
years and requires significant resources. In most cases, if the FDA has not approved a potential drug compound for sale in the
United States, the potential drug compound may be exported for sale outside of the United States, only if it has been approved
in any one of the following: the European Union or a country in the European Economic Area (the countries in the European Union
and the European Free Trade Association) if the drug or device is marketed in that country or the drug or device is authorized
for general marketing in the European Economic Area, Canada, Australia, New Zealand, Japan, Israel, Switzerland and South Africa.
There are specific FDA regulations that govern this process.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>U.S. coverage and reimbursement </i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Significant uncertainty exists as to the coverage
and reimbursement status of any compound for which we may seek regulatory approval. Sales in the United States will depend in part
on the availability of sufficient coverage and adequate reimbursement from third-party payors, which include government health
programs such as Medicare, Medicaid, CHIP, TRICARE and the Veterans Administration, as well as managed care organizations and private
health insurers. Prices at which we or our customers seek reimbursement for our therapeutic compounds can be subject to challenge,
reduction or denial by payors.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The process for determining whether a payor
will provide coverage for a product is typically separate from the process for setting the reimbursement rate that the payor will
pay for the product. A payor&#8217;s decision to provide coverage for a product does not imply that an adequate reimbursement rate
will be available. Additionally, in the United States there is no uniform policy among payors for coverage or reimbursement. Third-party
payors often rely upon Medicare coverage policy and payment limitations in setting their own coverage and reimbursement policies,
but also have their own methods and approval processes. Therefore, coverage and reimbursement for products can differ significantly
from payor to payor. If coverage and adequate reimbursement are not available, or are available only at limited levels, successful
commercialization of, and obtaining a satisfactory financial return on, any product we develop may not be possible.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Third-party payors are increasingly challenging
the price and examining the medical necessity and cost-effectiveness of medical products and services, in addition to their safety
and efficacy. In order to obtain coverage and reimbursement for any product that might be approved for marketing, we may need to
conduct expensive studies in order to demonstrate the medical necessity and cost-effectiveness of any products, which would be
in addition to the costs expended to obtain regulatory approvals. Third-party payors may not consider our compounds to be medically
necessary or cost-effective compared to other available therapies, or the rebate percentages required to secure favorable coverage
may not yield an adequate margin over cost or may not enable us to maintain price levels sufficient to realize an appropriate return
on our investment in drug development.<span style="color: black"> Additionally, we or our collaborators may develop companion diagnostic
tests for use with our product candidates. Companion diagnostic tests require coverage and reimbursement separate and apart from
the coverage and reimbursement for their companion pharmaceutical or biological products. Similar challenges to obtaining coverage
and reimbursement, applicable to pharmaceutical or biological products, will apply to companion diagnostics.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 26; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->27<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>Fraud and Abuse Laws </i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Federal and state health care laws and regulations
restrict business practices in the biopharmaceutical industry. In the biopharmaceutical industry, there are a number of federal
and state health care regulatory requirements that apply to entities, including, but not limited to, the federal and state fraud
and abuse laws. These laws include, but are not limited to, anti-kickback and self-referral law, civil false claims act law, criminal
false statement law, civil monetary penalty laws, exclusion law, and other civil, criminal, and administrative laws. Health care
laws, regulations, and guidance continuously evolve and are thereby subject to constant change.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Federal Anti-Kickback Statute, 42 U.S.C.
&#167; 1320a-7b(b), among other things, prohibits the knowing and willful offer, payment, solicitation or receipt of any form of
remuneration, whether directly or indirectly and overtly or covertly in cash or in kind, in return for, or to induce the referral
of an individual for the:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;&#9679;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">furnishing
    or arranging for the furnishing of items or services reimbursable in whole or in part under Medicare, Medicaid or other federal
    healthcare programs; or</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">purchase,
    lease, or order of, or the arrangement or recommendation of the purchasing, leasing, or ordering of any item or service reimbursable
    in whole or in part under Medicare, Medicaid or other federal healthcare programs.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">There are a number of narrow safe harbors to
the Federal Anti-Kickback Statute. Such safe harbors permit certain payments and business practices that, although they would otherwise
potentially implicate the Federal Anti-Kickback Statute, are not treated as an offense under the same if all of the requirements
of the specific applicable safe harbor are met. Actual knowledge of the statute or specific intent to violate it is not required
in order for a person or entity to have committed a violation.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Federal Anti-Kickback Statute applies to
certain arrangements with healthcare providers, product end users and other parties, including marketing arrangements and discounts
and other financial incentives offered in connection with the sales of our products. Regulatory authorities may determine that
certain marketing, pricing, or other activities violate the Federal Anti-Kickback Statute or other applicable laws. Noncompliance
with the Federal Anti-Kickback Statute can result in civil, administrative and/or criminal penalties, restrictions on the ability
to operate in certain jurisdictions, and exclusion from participation in Medicare, Medicaid or other federal healthcare programs.
In addition, non-compliance can result in the need to curtail and/or restructure operations. Any penalties, damages, fines, exclusions,
curtailment or restructuring of operations could adversely affect the ability to operate a business, financial condition, and results
of operations. A violation of the Federal Anti-Kickback Statute can serve as a false or fraudulent claim for purposes of the civil
False Claims Act and the civil monetary penalties statute.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The federal Health Insurance Portability and
Accountability Act of 1996 (&#8220;HIPAA&#8221;) among other things, enacted numerous provisions that prohibit knowingly and willfully
executing, or attempting to execute, a scheme or artifice to defraud any healthcare benefit program or obtain, by means of false
or fraudulent pretenses, representations, or promises, any of the money or property owned by, or under the custody or control of,
any healthcare benefit program, regardless of the payor (e.g., public or private), willfully obstructing a criminal investigation
of a healthcare offense, and knowingly and willfully falsifying, concealing or covering up by any trick or device a material fact
or making any materially false, fictitious or fraudulent statements in connection with the delivery of, or payment for, healthcare
benefits, items or services relating to healthcare matters. These provisions include 18 U.S.C. &#167;&#167; 286, 287, 669, 1035,
1347, and 1518, all as described further below.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 27; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->28<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Ethics in Patient Referrals Act, commonly
known as the &#8220;Stark Law,&#8221; 42 U.S.C. &#167; 1395nn, prohibits a physician from making referrals for certain &#8220;designated
health services&#8221; payable by Medicare to an entity in which the physician or an immediate family member of such physician
has an ownership or investment interest or with which the physician has entered into a compensation arrangement, unless a statutory
exception applies. There are a number of exceptions to the Stark Law. Such exceptions permit certain payments and arrangements
that, although they would otherwise potentially implicate the Stark Law, are not treated as a violation under the same if the requirements
of the specific exceptions are met. Violation of the Stark Law could result in denial of payment, disgorgement of reimbursements
received under a noncompliance arrangement, civil penalties, damages and exclusion from Medicare or other governmental programs.
These requirements are highly technical and there can be no guarantee that regulatory authorities will not determine or assert
that arrangements are in violation of the Stark Law and do not otherwise meet applicable Stark Law exceptions.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The federal false statements statute, 42 U.S.C.
&#167; 1320a-7b(a), prohibits knowingly and willfully falsifying, concealing, or omitting a material fact or making any materially
false statement in connection with the delivery of health care benefits, items, or services. Similarly, 18 U.S.C. &#167; 1035 prohibits
a person or entity, in any matter involving a health care benefit program, from knowingly or willfully falsifying, concealing,
or covering up by any trick, scheme, or device a material fact; making any materially false, fictitious, or fraudulent statements
or representations; or making or using any materially false writing or document knowing the same to contain any materially false,
fictitious, or fraudulent statement or entry. In addition to criminal penalties, violation of these statutes may result in collateral
administrative sanctions, including exclusion from participation in Medicare, Medicaid and other federal health care programs.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">18 U.S.C. &#167; 669 prohibits knowingly and
willfully embezzling, stealing, or otherwise without authority converting to the use of any person or entity other than the rightful
owner, or intentionally misapplying any of the moneys, funds, securities, premiums, credits, property, or other assets of a health
care benefit program. In addition to criminal penalties, violation of this statute may result in collateral administrative sanctions,
including exclusion from participation in Medicare, Medicaid and other federal health care programs.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The criminal health care fraud statute, 18
U.S.C. &#167; 1347, establishes criminal liability for whoever knowingly and willfully executes, or attempts to execute, a scheme
or artifice to defraud any health care benefit program, or to obtain, by means of false or fraudulent pretenses, representations,
or promises, any of the money or property owned by, or under the custody or control of, any health care benefit program, in connection
with the delivery of or payment for health care benefits, items, or services. In addition to criminal penalties, violation of this
statute may result in collateral administrative sanctions, including exclusion from participation in Medicare, Medicaid and other
federal health care programs. A person or entity need not have actual knowledge of this law or specific intent to commit a violation
of this law.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">18 U.S.C. &#167; 1518 establishes criminal
liability for whoever willfully prevents, obstructs, misleads, delays or attempts to prevent, obstruct, mislead, or delay the communication
of information or records relating to a violation of a Federal health care offense to a criminal investigator. In addition to criminal
penalties, violation of this statute may result in collateral administrative sanctions, including exclusion from participation
in Medicare, Medicaid and other federal health care programs.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">18 U.S.C. &#167; 286 establishes criminal liability
for whoever enters into any agreement, combination, or conspiracy to defraud the United States, or any department or agency thereof,
by obtaining or aiding to obtain the payment or allowance of any false, fictitious or fraudulent claim. In addition to criminal
penalties, violation of this statute may result in collateral administrative sanctions, including exclusion from participation
in Medicare, Medicaid and other federal health care programs.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">18 U.S.C. &#167; 287 establishes criminal liability
for whoever knowingly makes or presents a false, fictitious or fraudulent claim to the United States Government, including any
department or agency thereof. In addition to criminal penalties, violation of this statute may result in collateral administrative
sanctions, including exclusion from participation in Medicare, Medicaid and other federal health care programs.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 28; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->29<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Federal False Claims Act, 31 U.S.C. &#167;
3729, et seq., provides, in part, that the federal government&#8212;or a private party on behalf of the government&#8212;may bring
a lawsuit against any person whom it believes has knowingly presented, or caused to be presented, a false or fraudulent claim for
payment, or who has made a false statement or used a false record to get a claim paid or to avoid, decrease or conceal an obligation
to pay money to the federal government or who has knowingly retained an overpayment. Knowledge under the Federal False Claims Act
means actual knowledge, deliberate indifference, or reckless disregard. In addition, amendments in 1986 to the Federal False Claims
Act have made it easier for private parties to bring whistleblower lawsuits against companies.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The civil monetary penalties law, 42 U.S.C.
&#167; 1320a-7a, provides, in part, that the federal government may seek civil monetary penalties against any person who presents
or causes to be presented claims to a Federal health care program that the person knows or should know is for an item or services
that was not provided as claimed or is false or fraudulent, or the person has made a false statement or used a false record to
get a claim paid. The federal government may also seek civil monetary penalties for a wide variety of other conduct, including
offering remuneration to influence a Medicare or Medicaid beneficiary&#8217;s selection of providers and violations of the Federal
Anti-Kickback Statute.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Violations of the Federal False Claims Act
and/or the Civil Monetary Penalties Law can result in penalties ranging from $12,537 to $25,076 for each false claim violation
of the Federal False Claims Act and varying amounts based on the type of violation of the Civil Monetary Penalties Law, plus up
to three times the amount of damages that the federal government sustained. In addition, the federal government may also seek exclusion
from participation in all federal health care programs.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">42 U.S.C. Section 1320a-7 provides that individuals
and entities can be mandatorily or permissively excluded from participation in federal health care programs. The grounds for mandatory
exclusion include, but are not limited to, conviction for a criminal offense related to the delivery of an item or service reimbursed
under a federal or state health care program, and a conviction related to health care fraud. The grounds for permissive exclusion
include, but are not limited to, criminal offenses relating to fraud inside and outside of health care, convictions related to
obstruction of an investigation or audit, and/or failure to disclose certain required information. Exclusion from federal health
care programs&#8212;whether mandatory or permissive&#8212;may mean that our customers may not be able to get reimbursed by federal
and/or state health care programs for use or dispensing of our products.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>State Fraud and Abuse Provisions</i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Many states have also adopted some form of
anti-kickback and anti-referral laws and false claims acts and civil monetary penalties and other fraud and abuse provisions that
apply regardless of payer, in addition to items and services reimbursed under Medicaid and other state programs. A determination
of liability under such laws could result in fines, penalties, and exclusion, as well as restrictions on the ability to operate
in these jurisdictions.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Corporate liability can be present as a result
of the illegal activities of employees, representatives, contractors, collaborators, agents, subsidiaries, or affiliates, even
if they were not explicitly authorized. There can be no assurance that all employees, representatives, contractors, collaborators,
agents, subsidiaries or affiliates will comply with the foregoing laws at all times. Violation of the aforementioned and other
laws could result in whistleblower complaints, investigations, sanctions, settlements, prosecution, government oversight and reporting,
other enforcement actions, disgorgement of profits, significant fines, damages, other civil and criminal penalties or injunctions
or other administrative remedies, suspension and/or debarment from contracting with certain governments or other persons, the loss
of privileges, reputational harm, contract damages, adverse media coverage and other collateral consequences. In addition, corporate
directors, officers, employees, and other representatives who engage in violations of these and other laws may face imprisonment,
fines, and penalties. If any subpoenas or investigations are launched, or governmental or other sanctions are imposed, or if a
company does not prevail in any possible civil or criminal litigation, business, financial condition, and results of operations
could be materially harmed. In addition, responding to any action will likely result in a materially significant diversion of management&#8217;s
attention and resources and significant defense costs and other professional fees. Enforcement actions and sanctions could further
harm business, financial condition, and results of operations. Any of the consequences contained in this paragraph and section
could adversely affect the ability to operate the business, financial condition, and the results of operations.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 29; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->30<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>Sunshine Act</i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Sunshine Act requires manufacturers of
products reimbursed by Medicare, Medicaid or the Children&#8217;s Health Insurance Program (&#8220;CHIP&#8221;) to collect and
annually report detailed data to the Centers for Medicare and Medicaid Services (&#8220;CMS&#8221;) regarding payments or other
transfers of value to physicians,<span style="color: black"> certain other health care providers (such as physicians assistants
and nurse practitioners),</span> and teaching hospitals (&#8220;covered recipients&#8221;), as well as any ownership or investment
interest held by physicians and their immediate family members. The reporting data must be accompanied by an attestation as to
the accuracy of the data and failure to timely and accurately submit required information may result in civil monetary penalties.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>Health Insurance Portability and Accountability
Act </i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Besides enacting the program integrity provisions
described above, HIPAA, also created a new set of privacy and security requirements. As amended by the Health Information Technology
for Economic and Clinical Health Act, and implementing regulations thereunder, HIPAA requires certain healthcare providers, health
plans and healthcare clearinghouses who conduct specified electronic healthcare transactions (&#8220;covered entities&#8221;),
as well as their independent contractors and agents who conduct certain activities involving protected health information on their
behalf (&#8220;business associates&#8221;) to comply with enumerated requirements relating to the privacy, security and transmission
of protected health information. Failure to comply with HIPAA can result in corrective action, as well as civil fines and penalties
and government oversight. Among other changes, HITECH made HIPAA security standards directly applicable to business associates,
increased the tiered civil and criminal fines and penalties that may be imposed against covered entities, business associates and
possibly other persons, and gave state attorneys general new authority to file actions to enforce HIPAA. Further, the breach notification
rule implemented under HITECH requires covered entities to notify affected individuals, the U.S. Department of Health and Human
Services Office of Civil Rights (&#8220;OCR&#8221;), the agency that enforces HIPAA, and for breaches affecting more than 500 individuals,
the media, of any breaches of unsecured protected health information. HIPAA does not create a private right of action for individuals,
though individuals may submit complaints related to HIPAA to OCR.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>Legislative Activities Aimed at Controlling
Drug Costs </i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In the United States, there have been, and
continue to be proposed and enacted legislation at the federal and state levels designed to, among other things, bring more transparency
to drug pricing, review the relationship between pricing and manufacturer patient programs, reduce the cost of drugs under Medicare,
and reform government program reimbursement methodologies for drugs. For example, in July 2021, the Biden administration released
an executive order, &#8220;Promoting Competition in the American Economy,&#8221; with multiple provisions aimed at prescription
drugs. In response to Biden&#8217;s executive order, on September 9, 2021, the U.S. Department of Health and Human Services (&#8220;HHS&#8221;)
released a Comprehensive Plan for Addressing High Drug Prices that outlines principles for drug pricing reform and sets out a variety
of potential legislative policies that Congress could pursue as well as potential administrative actions HHS can take to advance
these principles. In addition, the Inflation Reduction Act (&#8220;IRA&#8221;) passed on August 16, 2022. The IRA, among other
things, (1) directs HHS to negotiate the price of certain highly-utilized single-source drugs and biologics covered under Medicare
and (2) imposes rebates under Medicare Part B and Medicare Part D to penalize price increases that outpace inflation. These provisions
will take effect progressively starting in fiscal year 2023, although they may be subject to legal challenges. It is currently
unclear how the IRA will be implemented but is likely to have a significant impact on the pharmaceutical industry. Further, the
Biden administration released an additional executive order on October 14, 2022, directing HHS to submit a report within 90 days
on how the Center for Medicare and Medicaid Innovation can be further leveraged to test new models for lowering drug costs for
Medicare and Medicaid beneficiaries. We expect that additional U.S. federal healthcare reform measures will be adopted in the future,
any of which could limit the amounts that the U.S. federal government will pay for healthcare products and services, which could
result in reduced demand for our product candidates or additional pricing pressures.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 30; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->31<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Research and Development Expenses</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Historically, a significant portion of our
operating expenses has related to research and development. See our Consolidated Financial Statements contained elsewhere in this
Annual Report for costs and expenses related to research and development, and other financial information for fiscal years 2023,
2022 and 2021.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Scientific Advisors </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="color: black">We are advised by
scientists and physicians with experience relevant to our Company and our product candidates.</span> Our scientific advisors include
clinicians and scientists who are affiliated with a number of highly regarded medical institutions.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Employees</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We currently have approximately forty full-time
employees, and we retain several independent contractors on a regular or as-needed basis. We believe that we have good relations
with our employees.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Available Information</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Our internet website address is www.anavex.com.
Our Annual Reports on Form 10-K, Quarterly Reports on Form 10-Q, Current Reports on Form 8-K and amendments to those reports filed
or furnished pursuant to section 13(a) or 15(d) of the Exchange Act are available there free of charge. We include our website
address in this report only as an inactive textual reference and do not intend it to be an active link to our website. The contents
of our website are not incorporated into this report.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_003"></span>ITEM 1A. RISK
FACTORS</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>Risk Factor Summary</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The following is a summary of the risks and
uncertainties that could cause our business, financial condition or operating results to be harmed. We encourage you to carefully
review the full risk factors contained in this report in their entirety for additional information regarding these risks and uncertainties.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Our
                                                                                                                              history
                                                                                                                              of
                                                                                                                              losses
                                                                                                                              and
                                                                                                                              no
                                                                                                                              revenue
                                                                                                                              raises
                                                                                                                              a
                                                                                                                              risk
                                                                                                                              regarding
                                                                                                                              our
                                                                                                                              ability
                                                                                                                              to
                                                                                                                              continue
                                                                                                                              as
                                                                                                                              a
                                                                                                                              going
                                                                                                                              concern
                                                                                                                              in
                                                                                                                              the
                                                                                                                              future;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">We
                                                                                                                              have
                                                                                                                              a
                                                                                                                              very
                                                                                                                              limited
                                                                                                                              relevant
                                                                                                                              operating
                                                                                                                              history
                                                                                                                              upon
                                                                                                                              which
                                                                                                                              an
                                                                                                                              evaluation
                                                                                                                              of
                                                                                                                              our
                                                                                                                              performance
                                                                                                                              and
                                                                                                                              prospects
                                                                                                                              can
                                                                                                                              be
                                                                                                                              made.
                                                                                                                              We
                                                                                                                              may
                                                                                                                              never
                                                                                                                              be
                                                                                                                              able
                                                                                                                              to
                                                                                                                              successfully
                                                                                                                              develop
                                                                                                                              marketable
                                                                                                                              products
                                                                                                                              or
                                                                                                                              generate
                                                                                                                              any
                                                                                                                              revenue.
                                                                                                                              If
                                                                                                                              we
                                                                                                                              cannot
                                                                                                                              generate
                                                                                                                              sufficient
                                                                                                                              revenues,
                                                                                                                              we
                                                                                                                              may
                                                                                                                              suspend
                                                                                                                              or
                                                                                                                              cease
                                                                                                                              operations;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Our
                                                                                                                              research
                                                                                                                              and
                                                                                                                              development
                                                                                                                              plans
                                                                                                                              will
                                                                                                                              require
                                                                                                                              substantial
                                                                                                                              additional
                                                                                                                              future
                                                                                                                              funding.
                                                                                                                              We
                                                                                                                              may
                                                                                                                              be
                                                                                                                              unable
                                                                                                                              to
                                                                                                                              raise
                                                                                                                              capital
                                                                                                                              when
                                                                                                                              needed,
                                                                                                                              which
                                                                                                                              would
                                                                                                                              force
                                                                                                                              us
                                                                                                                              to
                                                                                                                              delay,
                                                                                                                              reduce
                                                                                                                              or
                                                                                                                              eliminate
                                                                                                                              our
                                                                                                                              research
                                                                                                                              and
                                                                                                                              development
                                                                                                                              activities;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Even
                                                                                                                              if
                                                                                                                              our
                                                                                                                              products
                                                                                                                              are
                                                                                                                              approved,
                                                                                                                              we
                                                                                                                              may
                                                                                                                              not
                                                                                                                              be
                                                                                                                              able
                                                                                                                              to
                                                                                                                              generate
                                                                                                                              significant
                                                                                                                              revenues
                                                                                                                              from
                                                                                                                              or
                                                                                                                              successfully
                                                                                                                              commercialize
                                                                                                                              them,
                                                                                                                              which
                                                                                                                              will
                                                                                                                              adversely
                                                                                                                              affect
                                                                                                                              our
                                                                                                                              financial
                                                                                                                              results
                                                                                                                              and
                                                                                                                              financial
                                                                                                                              condition
                                                                                                                              and
                                                                                                                              we
                                                                                                                              will
                                                                                                                              have
                                                                                                                              to
                                                                                                                              delay
                                                                                                                              or
                                                                                                                              terminate
                                                                                                                              some
                                                                                                                              or
                                                                                                                              all
                                                                                                                              of
                                                                                                                              our
                                                                                                                              research
                                                                                                                              and
                                                                                                                              development
                                                                                                                              plans
                                                                                                                              which
                                                                                                                              may
                                                                                                                              force
                                                                                                                              us
                                                                                                                              to
                                                                                                                              cease
                                                                                                                              operations;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">If
                                                                                                                              we
                                                                                                                              or
                                                                                                                              any
                                                                                                                              companion
                                                                                                                              diagnostic
                                                                                                                              collaborator
                                                                                                                              of
                                                                                                                              ours
                                                                                                                              are
                                                                                                                              unable
                                                                                                                              to
                                                                                                                              timely
                                                                                                                              develop
                                                                                                                              and
                                                                                                                              obtain
                                                                                                                              regulatory
                                                                                                                              approval
                                                                                                                              for
                                                                                                                              companion
                                                                                                                              diagnostic
                                                                                                                              tests
                                                                                                                              for
                                                                                                                              our
                                                                                                                              drug
                                                                                                                              candidates,
                                                                                                                              we
                                                                                                                              may
                                                                                                                              not
                                                                                                                              realize
                                                                                                                              the
                                                                                                                              commercial
                                                                                                                              potential
                                                                                                                              of
                                                                                                                              our
                                                                                                                              drug
                                                                                                                              candidates;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Regulatory
                                                                                                                              authorities
                                                                                                                              may
                                                                                                                              not
                                                                                                                              accept
                                                                                                                              data
                                                                                                                              from
                                                                                                                              our
                                                                                                                              trials
                                                                                                                              conducted
                                                                                                                              outside
                                                                                                                              the
                                                                                                                              United
                                                                                                                              States;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Fast
                                                                                                                              Track
                                                                                                                              designation
                                                                                                                              or
                                                                                                                              breakthrough
                                                                                                                              therapy
                                                                                                                              designation
                                                                                                                              that
                                                                                                                              we
                                                                                                                              have
                                                                                                                              received
                                                                                                                              or
                                                                                                                              may
                                                                                                                              seek
                                                                                                                              out
                                                                                                                              may
                                                                                                                              not
                                                                                                                              actually
                                                                                                                              lead
                                                                                                                              to
                                                                                                                              a
                                                                                                                              faster
                                                                                                                              FDA
                                                                                                                              review
                                                                                                                              and
                                                                                                                              approval
                                                                                                                              process;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif"></span></p>

<!-- Field: Page; Sequence: 31; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->32<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">We
                                                                                                                              may
                                                                                                                              be
                                                                                                                              unable
                                                                                                                              to
                                                                                                                              maintain
                                                                                                                              any
                                                                                                                              benefits
                                                                                                                              associated
                                                                                                                              with
                                                                                                                              orphan
                                                                                                                              drug
                                                                                                                              designation,
                                                                                                                              including
                                                                                                                              market
                                                                                                                              exclusivity;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">If
                                                                                                                              we
                                                                                                                              fail
                                                                                                                              to
                                                                                                                              demonstrate
                                                                                                                              efficacy
                                                                                                                              in
                                                                                                                              our
                                                                                                                              non-clinical
                                                                                                                              studies
                                                                                                                              and
                                                                                                                              clinical
                                                                                                                              trials
                                                                                                                              our
                                                                                                                              future
                                                                                                                              business
                                                                                                                              prospects,
                                                                                                                              financial
                                                                                                                              condition
                                                                                                                              and
                                                                                                                              operating
                                                                                                                              results
                                                                                                                              will
                                                                                                                              be
                                                                                                                              materially
                                                                                                                              adversely
                                                                                                                              affected;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">If
                                                                                                                              we
                                                                                                                              do
                                                                                                                              not
                                                                                                                              obtain
                                                                                                                              the
                                                                                                                              support
                                                                                                                              of
                                                                                                                              qualified
                                                                                                                              scientific
                                                                                                                              collaborators,
                                                                                                                              our
                                                                                                                              revenue,
                                                                                                                              growth
                                                                                                                              and
                                                                                                                              profitability
                                                                                                                              will
                                                                                                                              likely
                                                                                                                              be
                                                                                                                              limited,
                                                                                                                              which
                                                                                                                              would
                                                                                                                              have
                                                                                                                              a
                                                                                                                              material
                                                                                                                              adverse
                                                                                                                              effect
                                                                                                                              on
                                                                                                                              our
                                                                                                                              business;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">We
                                                                                                                              may
                                                                                                                              not
                                                                                                                              be
                                                                                                                              able
                                                                                                                              to
                                                                                                                              develop,
                                                                                                                              market
                                                                                                                              or
                                                                                                                              generate
                                                                                                                              sales
                                                                                                                              of
                                                                                                                              our
                                                                                                                              products
                                                                                                                              to
                                                                                                                              the
                                                                                                                              extent
                                                                                                                              anticipated.
                                                                                                                              Our
                                                                                                                              business
                                                                                                                              may
                                                                                                                              fail
                                                                                                                              and
                                                                                                                              investors
                                                                                                                              could
                                                                                                                              lose
                                                                                                                              all
                                                                                                                              their
                                                                                                                              investment
                                                                                                                              in
                                                                                                                              our
                                                                                                                              Company;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">None
                                                                                                                              of
                                                                                                                              our
                                                                                                                              potential
                                                                                                                              drug
                                                                                                                              compounds
                                                                                                                              may
                                                                                                                              reach
                                                                                                                              the
                                                                                                                              commercial
                                                                                                                              market
                                                                                                                              and
                                                                                                                              our
                                                                                                                              business
                                                                                                                              may
                                                                                                                              fail;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Our
                                                                                                                              technologies
                                                                                                                              and
                                                                                                                              future
                                                                                                                              products
                                                                                                                              may
                                                                                                                              be
                                                                                                                              rendered
                                                                                                                              undesirable
                                                                                                                              or
                                                                                                                              obsolete
                                                                                                                              if
                                                                                                                              our
                                                                                                                              competitors
                                                                                                                              succeed
                                                                                                                              in
                                                                                                                              developing
                                                                                                                              products
                                                                                                                              and
                                                                                                                              technologies
                                                                                                                              faster
                                                                                                                              or
                                                                                                                              that
                                                                                                                              are
                                                                                                                              more
                                                                                                                              effective
                                                                                                                              or
                                                                                                                              with
                                                                                                                              a
                                                                                                                              better
                                                                                                                              profile
                                                                                                                              than
                                                                                                                              our
                                                                                                                              own,
                                                                                                                              or
                                                                                                                              if
                                                                                                                              scientific
                                                                                                                              developments
                                                                                                                              change
                                                                                                                              our
                                                                                                                              understanding
                                                                                                                              of
                                                                                                                              the
                                                                                                                              potential
                                                                                                                              scope
                                                                                                                              and
                                                                                                                              utility
                                                                                                                              of
                                                                                                                              our
                                                                                                                              potential
                                                                                                                              products;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">We
                                                                                                                              have
                                                                                                                              advanced
                                                                                                                              our
                                                                                                                              research
                                                                                                                              and
                                                                                                                              development
                                                                                                                              efforts
                                                                                                                              on
                                                                                                                              the
                                                                                                                              treatment
                                                                                                                              of
                                                                                                                              neurodegenerative
                                                                                                                              and
                                                                                                                              central
                                                                                                                              nervous
                                                                                                                              system,
                                                                                                                              or
                                                                                                                              CNS,
                                                                                                                              disorders,
                                                                                                                              a
                                                                                                                              field
                                                                                                                              that
                                                                                                                              has
                                                                                                                              seen
                                                                                                                              very
                                                                                                                              limited
                                                                                                                              success
                                                                                                                              in
                                                                                                                              product
                                                                                                                              development;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Our
                                                                                                                              reliance
                                                                                                                              on
                                                                                                                              third
                                                                                                                              parties
                                                                                                                              may
                                                                                                                              result
                                                                                                                              in
                                                                                                                              delays
                                                                                                                              in
                                                                                                                              completing,
                                                                                                                              or
                                                                                                                              a
                                                                                                                              failure
                                                                                                                              to
                                                                                                                              complete,
                                                                                                                              non-clinical
                                                                                                                              testing
                                                                                                                              or
                                                                                                                              clinical
                                                                                                                              trials
                                                                                                                              if
                                                                                                                              they
                                                                                                                              fail
                                                                                                                              to
                                                                                                                              perform
                                                                                                                              under
                                                                                                                              our
                                                                                                                              agreements
                                                                                                                              with
                                                                                                                              them
                                                                                                                              or
                                                                                                                              non-compliance
                                                                                                                              with
                                                                                                                              regulations;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">If
                                                                                                                              we
                                                                                                                              fail
                                                                                                                              to
                                                                                                                              compete
                                                                                                                              with
                                                                                                                              respect
                                                                                                                              to
                                                                                                                              partnering,
                                                                                                                              licensing,
                                                                                                                              mergers,
                                                                                                                              acquisitions,
                                                                                                                              joint
                                                                                                                              venture
                                                                                                                              and
                                                                                                                              other
                                                                                                                              collaboration
                                                                                                                              opportunities,
                                                                                                                              our
                                                                                                                              ability
                                                                                                                              to
                                                                                                                              research
                                                                                                                              and
                                                                                                                              develop
                                                                                                                              our
                                                                                                                              potential
                                                                                                                              drug
                                                                                                                              compounds
                                                                                                                              may
                                                                                                                              be
                                                                                                                              limited;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">The
                                                                                                                              use
                                                                                                                              of
                                                                                                                              any
                                                                                                                              of
                                                                                                                              our
                                                                                                                              products
                                                                                                                              in
                                                                                                                              clinical
                                                                                                                              trials
                                                                                                                              may
                                                                                                                              expose
                                                                                                                              us
                                                                                                                              to
                                                                                                                              liability
                                                                                                                              claims,
                                                                                                                              causing
                                                                                                                              our
                                                                                                                              business
                                                                                                                              to
                                                                                                                              suffer;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">If
                                                                                                                              we
                                                                                                                              are
                                                                                                                              unable
                                                                                                                              to
                                                                                                                              safeguard
                                                                                                                              against
                                                                                                                              security
                                                                                                                              breaches
                                                                                                                              with
                                                                                                                              respect
                                                                                                                              to
                                                                                                                              our
                                                                                                                              information
                                                                                                                              systems,
                                                                                                                              our
                                                                                                                              business
                                                                                                                              may
                                                                                                                              be
                                                                                                                              adversely
                                                                                                                              affected;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Continuing
                                                                                                                              regulatory
                                                                                                                              obligations
                                                                                                                              and
                                                                                                                              ongoing
                                                                                                                              regulatory
                                                                                                                              review
                                                                                                                              may
                                                                                                                              result
                                                                                                                              in
                                                                                                                              additional
                                                                                                                              expense.
                                                                                                                              Our
                                                                                                                              compounds
                                                                                                                              could
                                                                                                                              be
                                                                                                                              subject
                                                                                                                              to
                                                                                                                              restrictions
                                                                                                                              on
                                                                                                                              marketing
                                                                                                                              or
                                                                                                                              withdrawal
                                                                                                                              from
                                                                                                                              the
                                                                                                                              market,
                                                                                                                              and
                                                                                                                              we
                                                                                                                              may
                                                                                                                              be
                                                                                                                              subject
                                                                                                                              to
                                                                                                                              penalties
                                                                                                                              when
                                                                                                                              and
                                                                                                                              if
                                                                                                                              any
                                                                                                                              of
                                                                                                                              them
                                                                                                                              are
                                                                                                                              approved;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">We
                                                                                                                              receive
                                                                                                                              Australian
                                                                                                                              government
                                                                                                                              research
                                                                                                                              and
                                                                                                                              development
                                                                                                                              income
                                                                                                                              tax
                                                                                                                              incentive
                                                                                                                              refunds.
                                                                                                                              Loss
                                                                                                                              of
                                                                                                                              access
                                                                                                                              to
                                                                                                                              such
                                                                                                                              incentives
                                                                                                                              could
                                                                                                                              have
                                                                                                                              a
                                                                                                                              negative
                                                                                                                              effect
                                                                                                                              on
                                                                                                                              our
                                                                                                                              future
                                                                                                                              cash
                                                                                                                              flows
                                                                                                                              and
                                                                                                                              the
                                                                                                                              funding
                                                                                                                              of
                                                                                                                              future
                                                                                                                              research
                                                                                                                              and
                                                                                                                              development
                                                                                                                              projects;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Operating
                                                                                                                              our
                                                                                                                              business
                                                                                                                              internationally
                                                                                                                              carries
                                                                                                                              various
                                                                                                                              risks
                                                                                                                              which
                                                                                                                              could
                                                                                                                              materially
                                                                                                                              adversely
                                                                                                                              affect
                                                                                                                              our
                                                                                                                              business;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Our
                                                                                                                              ability
                                                                                                                              to
                                                                                                                              use
                                                                                                                              our
                                                                                                                              net
                                                                                                                              operating
                                                                                                                              loss
                                                                                                                              carryforwards
                                                                                                                              and
                                                                                                                              tax
                                                                                                                              credit
                                                                                                                              carryforwards
                                                                                                                              may
                                                                                                                              be
                                                                                                                              subject
                                                                                                                              to
                                                                                                                              limitation;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Healthcare
                                                                                                                              laws
                                                                                                                              and
                                                                                                                              regulations
                                                                                                                              could
                                                                                                                              expose
                                                                                                                              us
                                                                                                                              to
                                                                                                                              criminal
                                                                                                                              sanctions,
                                                                                                                              civil
                                                                                                                              and
                                                                                                                              administrative
                                                                                                                              penalties,
                                                                                                                              contractual
                                                                                                                              damages,
                                                                                                                              reputational
                                                                                                                              harm
                                                                                                                              and
                                                                                                                              diminished
                                                                                                                              profits
                                                                                                                              and
                                                                                                                              future
                                                                                                                              earnings,
                                                                                                                              among
                                                                                                                              other
                                                                                                                              penalties;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">We
                                                                                                                              expect
                                                                                                                              current
                                                                                                                              and
                                                                                                                              future
                                                                                                                              legislation
                                                                                                                              affecting
                                                                                                                              the
                                                                                                                              pharmaceutical
                                                                                                                              industry,
                                                                                                                              including
                                                                                                                              drug
                                                                                                                              pricing
                                                                                                                              reform,
                                                                                                                              to
                                                                                                                              impact
                                                                                                                              our
                                                                                                                              business
                                                                                                                              generally,
                                                                                                                              which
                                                                                                                              could
                                                                                                                              adversely
                                                                                                                              affect
                                                                                                                              our
                                                                                                                              business
                                                                                                                              operations;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Failure
                                                                                                                              to
                                                                                                                              obtain
                                                                                                                              or
                                                                                                                              maintain
                                                                                                                              adequate
                                                                                                                              coverage
                                                                                                                              and
                                                                                                                              reimbursement
                                                                                                                              for
                                                                                                                              our
                                                                                                                              product
                                                                                                                              candidates,
                                                                                                                              if
                                                                                                                              approved,
                                                                                                                              could
                                                                                                                              limit
                                                                                                                              our
                                                                                                                              ability
                                                                                                                              to
                                                                                                                              market
                                                                                                                              those
                                                                                                                              products
                                                                                                                              and
                                                                                                                              decrease
                                                                                                                              our
                                                                                                                              ability
                                                                                                                              to
                                                                                                                              generate
                                                                                                                              product
                                                                                                                              revenue;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Issuing
                                                                                                                              additional
                                                                                                                              shares
                                                                                                                              of
                                                                                                                              common
                                                                                                                              stock
                                                                                                                              will
                                                                                                                              result
                                                                                                                              in
                                                                                                                              the
                                                                                                                              dilution
                                                                                                                              of
                                                                                                                              our
                                                                                                                              existing
                                                                                                                              stockholders
                                                                                                                              and
                                                                                                                              may
                                                                                                                              cause
                                                                                                                              our
                                                                                                                              stock
                                                                                                                              price
                                                                                                                              to
                                                                                                                              fall.
                                                                                                                              A
                                                                                                                              decline
                                                                                                                              in
                                                                                                                              our
                                                                                                                              stock
                                                                                                                              price
                                                                                                                              could
                                                                                                                              affect
                                                                                                                              our
                                                                                                                              ability
                                                                                                                              to
                                                                                                                              raise
                                                                                                                              further
                                                                                                                              working
                                                                                                                              capital
                                                                                                                              and
                                                                                                                              adversely
                                                                                                                              affect
                                                                                                                              our
                                                                                                                              operations.
                                                                                                                              Raising
                                                                                                                              funds
                                                                                                                              at
                                                                                                                              lower
                                                                                                                              prices
                                                                                                                              would
                                                                                                                              severely
                                                                                                                              dilute
                                                                                                                              existing
                                                                                                                              or
                                                                                                                              future
                                                                                                                              investors;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif"></span></p>

<!-- Field: Page; Sequence: 32; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->33<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Our
                                                                                                                              stock
                                                                                                                              price
                                                                                                                              has
                                                                                                                              been
                                                                                                                              volatile
                                                                                                                              and
                                                                                                                              may
                                                                                                                              be
                                                                                                                              volatile
                                                                                                                              in
                                                                                                                              the
                                                                                                                              future
                                                                                                                              and
                                                                                                                              our
                                                                                                                              common
                                                                                                                              stock
                                                                                                                              may
                                                                                                                              become
                                                                                                                              the
                                                                                                                              target
                                                                                                                              of
                                                                                                                              a
                                                                                                                              &#8220;short
                                                                                                                              squeeze&#8221;;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">If
                                                                                                                              we
                                                                                                                              fail
                                                                                                                              to
                                                                                                                              maintain
                                                                                                                              an
                                                                                                                              effective
                                                                                                                              system
                                                                                                                              of
                                                                                                                              internal
                                                                                                                              control
                                                                                                                              over
                                                                                                                              financial
                                                                                                                              reporting,
                                                                                                                              we
                                                                                                                              may
                                                                                                                              not
                                                                                                                              be
                                                                                                                              able
                                                                                                                              to
                                                                                                                              accurately
                                                                                                                              report
                                                                                                                              our
                                                                                                                              financial
                                                                                                                              results
                                                                                                                              or
                                                                                                                              prevent
                                                                                                                              fraud.
                                                                                                                              Our
                                                                                                                              disclosure
                                                                                                                              controls
                                                                                                                              and
                                                                                                                              procedures
                                                                                                                              may
                                                                                                                              not
                                                                                                                              prevent
                                                                                                                              or
                                                                                                                              detect
                                                                                                                              all
                                                                                                                              errors
                                                                                                                              or
                                                                                                                              acts
                                                                                                                              of
                                                                                                                              fraud.
                                                                                                                              As
                                                                                                                              a
                                                                                                                              result,
                                                                                                                              stockholders
                                                                                                                              could
                                                                                                                              lose
                                                                                                                              confidence
                                                                                                                              in
                                                                                                                              our
                                                                                                                              financial
                                                                                                                              and
                                                                                                                              other
                                                                                                                              public
                                                                                                                              reporting,
                                                                                                                              which
                                                                                                                              would
                                                                                                                              harm
                                                                                                                              our
                                                                                                                              business
                                                                                                                              and
                                                                                                                              the
                                                                                                                              trading
                                                                                                                              price
                                                                                                                              of
                                                                                                                              our
                                                                                                                              common
                                                                                                                              stock;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Patent
                                                                                                                              terms
                                                                                                                              may
                                                                                                                              be
                                                                                                                              inadequate
                                                                                                                              to
                                                                                                                              protect
                                                                                                                              our
                                                                                                                              competitive
                                                                                                                              position
                                                                                                                              on
                                                                                                                              our
                                                                                                                              product
                                                                                                                              candidates.
                                                                                                                              If
                                                                                                                              we
                                                                                                                              are
                                                                                                                              unable
                                                                                                                              to
                                                                                                                              obtain
                                                                                                                              and
                                                                                                                              maintain
                                                                                                                              sufficient
                                                                                                                              intellectual
                                                                                                                              property
                                                                                                                              protection
                                                                                                                              for
                                                                                                                              our
                                                                                                                              product
                                                                                                                              candidates,
                                                                                                                              our
                                                                                                                              competitors
                                                                                                                              could
                                                                                                                              develop
                                                                                                                              and
                                                                                                                              commercialize
                                                                                                                              product
                                                                                                                              candidates
                                                                                                                              similar
                                                                                                                              or
                                                                                                                              identical
                                                                                                                              to
                                                                                                                              ours,
                                                                                                                              and
                                                                                                                              our
                                                                                                                              ability
                                                                                                                              to
                                                                                                                              successfully
                                                                                                                              commercialize
                                                                                                                              our
                                                                                                                              product
                                                                                                                              candidates
                                                                                                                              may
                                                                                                                              be
                                                                                                                              impaired;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">If
                                                                                                                              we
                                                                                                                              fail
                                                                                                                              to
                                                                                                                              comply
                                                                                                                              with
                                                                                                                              our
                                                                                                                              obligations
                                                                                                                              in
                                                                                                                              intellectual
                                                                                                                              property
                                                                                                                              licensing
                                                                                                                              agreements
                                                                                                                              or
                                                                                                                              experience
                                                                                                                              disruptions
                                                                                                                              to
                                                                                                                              our
                                                                                                                              business
                                                                                                                              relationships
                                                                                                                              with
                                                                                                                              our
                                                                                                                              licensors,
                                                                                                                              we
                                                                                                                              could
                                                                                                                              lose
                                                                                                                              important
                                                                                                                              intellectual
                                                                                                                              property
                                                                                                                              rights.
                                                                                                                              If
                                                                                                                              we
                                                                                                                              are
                                                                                                                              unable
                                                                                                                              to
                                                                                                                              protect
                                                                                                                              the
                                                                                                                              confidentiality
                                                                                                                              of
                                                                                                                              our
                                                                                                                              trade
                                                                                                                              secrets,
                                                                                                                              our
                                                                                                                              business
                                                                                                                              would
                                                                                                                              be
                                                                                                                              harmed;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Intellectual
                                                                                                                              property
                                                                                                                              infringement
                                                                                                                              claims
                                                                                                                              may
                                                                                                                              adversely
                                                                                                                              affect
                                                                                                                              our
                                                                                                                              development
                                                                                                                              and
                                                                                                                              commercialization
                                                                                                                              efforts;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">We
                                                                                                                              may
                                                                                                                              be
                                                                                                                              subject
                                                                                                                              to
                                                                                                                              claims
                                                                                                                              that
                                                                                                                              our
                                                                                                                              employees,
                                                                                                                              consultants
                                                                                                                              or
                                                                                                                              independent
                                                                                                                              contractors
                                                                                                                              have
                                                                                                                              wrongfully
                                                                                                                              used
                                                                                                                              or
                                                                                                                              disclosed
                                                                                                                              confidential
                                                                                                                              information
                                                                                                                              of
                                                                                                                              third
                                                                                                                              parties
                                                                                                                              or
                                                                                                                              that
                                                                                                                              our
                                                                                                                              employees
                                                                                                                              have
                                                                                                                              wrongfully
                                                                                                                              used
                                                                                                                              or
                                                                                                                              disclosed
                                                                                                                              alleged
                                                                                                                              trade
                                                                                                                              secrets
                                                                                                                              of
                                                                                                                              their
                                                                                                                              former
                                                                                                                              employers;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Obtaining
                                                                                                                              and
                                                                                                                              maintaining
                                                                                                                              our
                                                                                                                              patent
                                                                                                                              protection
                                                                                                                              depends
                                                                                                                              on
                                                                                                                              compliance
                                                                                                                              with
                                                                                                                              various
                                                                                                                              requirements
                                                                                                                              imposed
                                                                                                                              by
                                                                                                                              governmental
                                                                                                                              patent
                                                                                                                              agencies.
                                                                                                                              Changes
                                                                                                                              in
                                                                                                                              patent
                                                                                                                              law
                                                                                                                              could
                                                                                                                              impair
                                                                                                                              our
                                                                                                                              ability
                                                                                                                              to
                                                                                                                              protect
                                                                                                                              our
                                                                                                                              product
                                                                                                                              candidates;</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">We
                                                                                                                              may
                                                                                                                              become
                                                                                                                              involved
                                                                                                                              in
                                                                                                                              lawsuits
                                                                                                                              to
                                                                                                                              protect
                                                                                                                              or
                                                                                                                              enforce
                                                                                                                              our
                                                                                                                              patents
                                                                                                                              or
                                                                                                                              other
                                                                                                                              intellectual
                                                                                                                              property;
                                                                                                                              and</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 0"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">We
                                                                                                                              may
                                                                                                                              fail
                                                                                                                              to
                                                                                                                              protect
                                                                                                                              our
                                                                                                                              intellectual
                                                                                                                              property
                                                                                                                              rights
                                                                                                                              or
                                                                                                                              the
                                                                                                                              confidentiality
                                                                                                                              of
                                                                                                                              our
                                                                                                                              trade
                                                                                                                              secrets.</span></td></tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 18pt; text-align: justify; text-indent: -18pt">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In addition to other information in this Annual
Report on Form 10-K, the following risk factors should be carefully considered in evaluating our business because such factors
may have a significant impact on our business, operating results, liquidity and financial condition. As a result of the risk factors
set forth below, actual results could differ materially from those projected in any forward-looking statements. Additional risks
and uncertainties not presently known to us, or that we currently consider to be immaterial, may also impact our business, operating
results, liquidity and financial condition. If any such risks occur, our business, operating results, liquidity and financial condition
could be materially affected in an adverse manner. Under such circumstances, the trading price of our securities could decline,
and you may lose all or part of your investment.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Risks Related to our Company</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>We have had a history of losses and no
revenue, which raises a risk regarding our ability to continue as a going concern in the future.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Since inception through September 30, 2023,
we have accumulated a deficit of approximately $293 million. We can offer no assurance that we will ever operate profitably or
that we will generate positive cash flow in the future. To date, we have not generated any revenues from our operations. Our history
of losses and no revenues creates a greater risk of our continued ability to continue as a going concern in the future. As a result,
our management expects the business to continue to experience negative cash flows for the foreseeable future and cannot predict
when, if ever, our business might become profitable. We will need to raise additional funds, and such funds may not be available
on commercially acceptable terms, if at all. If we are unable to raise funds on acceptable terms, we may not be able to execute
our business plan, take advantage of future opportunities, or respond to competitive pressures or unanticipated requirements. This
may seriously harm our business, financial condition and results of operations.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 33; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->34<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>We are an early clinical stage pharmaceutical
research and development company and may never be able to successfully develop marketable products or generate any revenue. We
have a very limited relevant operating history upon which an evaluation of our performance and prospects can be made. There is
no assurance that our future operations will result in profits. If we cannot generate sufficient revenues, we may suspend or cease
operations.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We are an early clinical stage company and
have not generated any revenues to date and have no operating history. Moreover, we cannot be certain that our research and development
efforts will be successful or, if successful, that our potential drug compounds will ever be approved for sale to pharmaceutical
companies or generate commercial revenues. We have no relevant operating history upon which an evaluation of our performance and
prospects can be made. We are subject to all of the business risks associated with a new enterprise, including, but not limited
to, risks of unforeseen capital requirements, failure of potential drug compounds either in non-clinical testing or in clinical
trials, failure to establish business relationships and competitive disadvantages against larger and more established companies.
If we fail to become profitable, we may suspend or cease operations.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>We will need additional funding and may
be unable to raise additional capital when needed, which would force us to delay, reduce or eliminate our research and development
activities.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">To date, we have funded our operations primarily
through private placement of our equity securities, and grants or draws under our &#8220;at the market offering&#8221; in connection
with an Amended and Restated Sales Agreement, dated May 1, 2020, with Cantor Fitzgerald &amp; Co. and SVB Leerink LLC (the &#8220;Sales
Agents&#8221;), pursuant to which we may offer and sell shares of common stock registered under an effective registration statement
from time to time through the Sales Agents or the through the Purchase Agreement with Lincoln Park Capital Fund, LLC (&#8220;Lincoln
Park&#8221;) pursuant to which the Company may direct Lincoln Park to purchase shares of common stock registered under an effective
registration statement. The Company currently does not have access to sell shares under the Sales Agreement. We will need to raise
additional funding and the current economic conditions may have a negative impact on our ability to raise additional needed capital
on terms that are favorable to our Company or at all. We may not be able to generate significant revenues for several years, if
at all. Until we can generate significant revenues, if ever, we expect to satisfy our future cash needs through equity or debt
financing. We cannot be certain that additional funding will be available on acceptable terms, or at all. If adequate funds are
not available, we may be required to delay, reduce the scope of, or eliminate one or more of our research and development activities.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Risks Related to our Business</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Even if we are able to develop our potential
drug compounds, we may not be able to receive regulatory approval, or if approved, we may not be able to generate significant revenues
or successfully commercialize our products, which will adversely affect our financial results and financial condition and we will
have to delay or terminate some or all of our research and development plans which may force us to cease operations.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">All of our potential drug compounds are exclusively
focused on SIGMAR1 which has not previously been the subject of any approved drug products and will require extensive additional
research and development, including non-clinical testing and clinical trials, as well as regulatory approvals, before we can market
them. In particular, human therapeutic products are subject to rigorous non-clinical and clinical testing and other approval procedures
of the FDA and similar regulatory authorities in other countries. Various federal statutes and regulations also govern or influence
testing, manufacturing, safety, labeling, storage, and record-keeping related to such products and their marketing. We cannot predict
if or when any of the potential drug compounds we intend to develop will be approved for marketing. There are many reasons that
we may fail in our efforts to develop our potential drug compounds. These include:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the
    possibility that non-clinical testing or clinical trials may show that our potential drug compounds are ineffective and/or
    cause harmful side effects;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 34; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->35<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">regulators
    may not authorize us to commence or continue a clinical trial or may impose a clinical hold or may limit the conduct of a
    clinical trial through the imposition of a partial clinical hold;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the
    number of patients required for clinical trials for our drug candidates may be larger than we anticipate, enrollment in these
    clinical trials may be slower than we anticipate, participants may drop out of these clinical trials at a higher rate than
    we anticipate or the duration of these clinical trials may be longer than we anticipate;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">our
    third-party contractors, including investigators, may fail to meet their contractual obligations to us in a timely manner,
    or at all, or may fail to comply with regulatory requirements;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">our
    potential drug compounds may prove to be too expensive to manufacture or administer to patients;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">our
    potential drug compounds may fail to receive necessary regulatory approvals from the United States Food and Drug Administration
    or foreign regulatory authorities in a timely manner, or at all;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">even
    if our potential drug compounds are approved, we may not be able to produce them in commercial quantities or at reasonable
    costs;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">even
    if our potential drug compounds are approved, they may not achieve commercial acceptance;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 20pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">regulatory
    or governmental authorities may apply restrictions to any of our potential drug compounds, which could adversely affect their
    commercial success; and</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the
    proprietary rights of other parties may prevent us or our potential collaborative partners from marketing our potential drug
    compounds.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If we fail to develop our potential drug compounds,
our financial results and financial condition will be adversely affected, we will have to delay or terminate some or all of our
research and development plans and may be forced to cease operations.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Our research and development plans will
require substantial additional future funding which could impact our operations and financial condition. </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">It will take several years before we can develop
potentially marketable products, if at all. Our research and development plans will require substantial additional capital, arising
from costs to:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">conduct
    research, non-clinical testing and human clinical trials;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">establish
    pilot scale and commercial scale manufacturing processes and facilities; and</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">establish
    and develop quality control, regulatory, marketing, sales, finance and administrative capabilities to support these programs.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Our future operating and capital needs will
depend on many factors, including:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the
    pace of scientific progress in our research and development programs and the magnitude of these programs;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the
    scope and results of pre-clinical testing and human clinical trials;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif"></span></p>

<!-- Field: Page; Sequence: 35; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->36<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif"></span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the
    time and costs involved in obtaining regulatory approvals;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the
    time and costs involved in preparing, filing, prosecuting, securing, maintaining and enforcing patents;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">competing
    technological and market developments;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">our
    ability to establish additional collaborations;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">changes
    in our existing collaborations;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the
    cost of manufacturing scale-up; and</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the
    effectiveness of our commercialization activities.</span></td></tr>
</table>
<p style="font: 12pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We base our outlook regarding the need for
funds on many uncertain variables. Such uncertainties include the success of our research initiatives, regulatory approvals, the
timing of events outside our direct control such as negotiations with potential strategic partners and other factors. Any of these
uncertain events can significantly change our cash requirements as they determine such one-time events as the receipt or payment
of major milestones and other payments.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Additional funds may be required to support
our operations and if we are unable to obtain them on favorable terms, we may be required to cease or reduce certain further research
and development programs of our drug product platform, sell some or all our intellectual property, merge with another entity or
scale back operations.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>If we or any companion diagnostic collaborator
of ours are unable to successfully develop and obtain regulatory approval for companion diagnostic tests for our drug candidates,
or experience significant delays in doing so, we may not realize the commercial potential of our drug candidates.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We analyze genomic data from clinical trials
to identify biomarkers, which we use in the analysis of our clinical trials.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Identification of these patients will require
the use and development of companion diagnostics. According to the FDA&#8217;s 2014 guidance document on In Vitro Companion Diagnostic
Devices, for novel therapeutic products that depend on the use of a diagnostic test and where the diagnostic device could be essential
for the safe and effective use of the corresponding therapeutic product, the premarket application for the companion diagnostic
device should be developed and approved or cleared contemporaneously with the therapeutic.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We do not have experience or capabilities in
developing or commercializing diagnostics. It may be necessary to resolve issues such as selectivity/specificity, analytical validation,
reproducibility, or clinical validation of companion diagnostics during the development and regulatory approval processes. Moreover,
even if data from preclinical studies and early clinical trials appear to support development of a companion diagnostic for a drug
candidate, data generated in later clinical trials may fail to support the analytical and clinical validation of the companion
diagnostic. We and our future collaborators may encounter difficulties in developing, obtaining regulatory approval for, manufacturing
and commercializing companion diagnostics similar to those we face with respect to our drug candidates, including issues with achieving
regulatory clearance or approval, production of sufficient quantities at commercial scale and with appropriate quality standards,
and in gaining market acceptance. If we are unable to successfully develop companion diagnostics for our drug candidates, or experience
delays in doing so, the development of these drug candidates may be adversely affected, these drug candidates may not obtain marketing
approval, and we may not realize the full commercial potential of any of these therapeutics that have or may obtain marketing approval.
We may not be able to enter into arrangements with another diagnostic company to develop and obtain regulatory approval for of
an alternative diagnostic test for use in connection with the development and commercialization of our drug candidates or do so
on commercially reasonable terms, which could adversely affect and/or delay the development or commercialization of our therapeutic
candidates or therapeutics.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 36; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->37<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Companion diagnostics are subject to regulation
by the FDA and comparable foreign regulatory authorities as medical devices and will likely require separate regulatory approval
prior to commercialization. If we or third parties are unable to successfully develop companion diagnostics for our drug candidates,
or experience delays in doing so:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the
    development of these drug candidates may be delayed because it may be difficult to identify patients for enrollment in our
    clinical trials in a timely manner;</span></td></tr>
</table>
<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">these
    drug candidates may not receive marketing approval if their safe and effective use depends on a companion diagnostic; and</span></td></tr>
</table>
<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">we
    may not realize the full commercial potential of these drug candidates that receive marketing approval if, among other reasons,
    we are unable to appropriately identify patients or types of tumors targeted by these drug candidates.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Even if our drug candidates and any associated
companion diagnostics are approved for marketing, the need for companion diagnostics may slow or limit adoption of our drug candidates.
Our drug candidates may be perceived negatively compared to alternative treatments that do not require the use of companion diagnostics,
either due to the additional cost of the companion diagnostic or the need to complete additional prior to administering our drug
candidates.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If any of these events were to occur, our business
and growth prospects would be harmed materially.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: #231F20"><b><i>All but one of our clinical
trials to date have been conducted outside<span style="letter-spacing: 0.05pt"> </span>the United States,<span style="letter-spacing: 0.05pt">
</span>and the FDA<span style="letter-spacing: -0.05pt"> </span>and other<span style="letter-spacing: 0.05pt"> </span>foreign<span style="letter-spacing: 0.05pt">
</span>regulatory<span style="letter-spacing: 0.05pt"> </span>authorities<span style="letter-spacing: 0.1pt"> </span>may not accept<span style="letter-spacing: 0.05pt">
</span>data from<span style="letter-spacing: 0.05pt"> </span>such trials.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: #231F20">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: #231F20">The acceptance<span style="letter-spacing: 0.1pt">
</span>of study<span style="letter-spacing: 0.05pt"> </span>data<span style="letter-spacing: 0.05pt"> </span>from<span style="letter-spacing: 0.05pt">
</span>clinical<span style="letter-spacing: 0.1pt"> </span>trials<span style="letter-spacing: 0.1pt"> </span>conducted<span style="letter-spacing: 0.05pt">
</span>outside<span style="letter-spacing: 0.05pt"> </span>the<span style="letter-spacing: 0.05pt"> </span>United<span style="letter-spacing: 0.05pt">
</span>States<span style="letter-spacing: 0.05pt"> </span>by the FDA<span style="letter-spacing: -0.05pt"> </span>may<span style="letter-spacing: 0.05pt">
</span>be subject<span style="letter-spacing: 0.05pt"> </span>to certain<span style="letter-spacing: 0.1pt"> </span>conditions<span style="letter-spacing: 0.1pt">
</span>or may<span style="letter-spacing: 0.05pt"> </span>not be accepted<span style="letter-spacing: 0.05pt"> </span>at all.<span style="letter-spacing: 0.05pt">
</span>In cases<span style="letter-spacing: 0.05pt"> </span>where data<span style="letter-spacing: 0.05pt"> </span>from<span style="letter-spacing: 0.05pt">
</span>foreign<span style="letter-spacing: 0.05pt"> </span>clinical<span style="letter-spacing: 0.1pt"> </span>trials<span style="letter-spacing: 0.1pt">
</span>are<span style="letter-spacing: 0.05pt"> </span>intended<span style="letter-spacing: 0.05pt"> </span>to serve<span style="letter-spacing: 0.05pt">
</span>as the<span style="letter-spacing: 0.05pt"> </span>sole<span style="letter-spacing: 0.05pt"> </span>basis<span style="letter-spacing: 0.05pt">
</span>for<span style="letter-spacing: 0.05pt"> </span>regulatory<span style="letter-spacing: 0.1pt"> </span>approval in the<span style="letter-spacing: 0.05pt">
</span>United<span style="letter-spacing: 0.05pt"> </span>States,<span style="letter-spacing: 0.05pt"> </span>the<span style="letter-spacing: 0.05pt">
</span>FDA<span style="letter-spacing: -0.05pt"> </span>will<span style="letter-spacing: 0.05pt"> </span>generally<span style="letter-spacing: 0.1pt">
</span>not approve<span style="letter-spacing: 0.05pt"> </span>the<span style="letter-spacing: 0.05pt"> </span>application<span style="letter-spacing: 0.1pt">
</span>on the<span style="letter-spacing: 0.05pt"> </span>basis<span style="letter-spacing: 0.05pt"> </span>of foreign<span style="letter-spacing: 0.05pt">
</span>data<span style="letter-spacing: 0.05pt"> </span>alone<span style="letter-spacing: 0.05pt"> </span>unless (i)<span style="letter-spacing: 0.05pt">
</span>the<span style="letter-spacing: 0.05pt"> </span>data<span style="letter-spacing: 0.05pt"> </span>are<span style="letter-spacing: 0.05pt">
</span>applicable<span style="letter-spacing: 0.1pt"> </span>to the<span style="letter-spacing: 0.05pt"> </span>United<span style="letter-spacing: 0.05pt">
</span>States<span style="letter-spacing: 0.05pt"> </span>population<span style="letter-spacing: 0.05pt"> </span>and United<span style="letter-spacing: 0.05pt">
</span>States<span style="letter-spacing: 0.05pt"> </span>medical<span style="letter-spacing: 0.1pt"> </span>practice;<span style="letter-spacing: 0.1pt">
</span>(ii)<span style="letter-spacing: 0.1pt"> </span>the<span style="letter-spacing: 0.05pt"> </span>trials<span style="letter-spacing: 0.1pt">
</span>were performed<span style="letter-spacing: 0.1pt"> </span>by clinical<span style="letter-spacing: 0.1pt"> </span>investigators<span style="letter-spacing: 0.15pt">
</span>of recognized<span style="letter-spacing: 0.1pt"> </span>competence<span style="letter-spacing: 0.1pt"> </span>and pursuant<span style="letter-spacing: 0.05pt">
</span>to good clinical<span style="letter-spacing: 0.1pt"> </span>practice<span style="letter-spacing: 0.1pt"> </span>regulations;
and (iii)<span style="letter-spacing: 0.1pt"> </span>the<span style="letter-spacing: 0.05pt"> </span>data<span style="letter-spacing: 0.05pt">
</span>may<span style="letter-spacing: 0.05pt"> </span>be considered<span style="letter-spacing: 0.1pt"> </span>valid<span style="letter-spacing: 0.05pt">
</span>without<span style="letter-spacing: 0.05pt"> </span>the<span style="letter-spacing: 0.05pt"> </span>need for<span style="letter-spacing: 0.05pt">
</span>an on-site<span style="letter-spacing: 0.1pt"> </span>inspection<span style="letter-spacing: 0.1pt"> </span>by the<span style="letter-spacing: 0.05pt">
</span>FDA,<span style="letter-spacing: -0.05pt"> </span>or if<span style="letter-spacing: 0.05pt"> </span>the<span style="letter-spacing: 0.05pt">
</span>FDA considers<span style="letter-spacing: 0.1pt"> </span>such inspection<span style="letter-spacing: 0.1pt"> </span>to be
necessary,<span style="letter-spacing: 0.1pt"> </span>the<span style="letter-spacing: 0.05pt"> </span>FDA<span style="letter-spacing: -0.05pt">
</span>is<span style="letter-spacing: 0.05pt"> </span>able<span style="letter-spacing: 0.05pt"> </span>to validate<span style="letter-spacing: 0.1pt">
</span>the<span style="letter-spacing: 0.05pt"> </span>data<span style="letter-spacing: 0.05pt"> </span>through<span style="letter-spacing: 0.05pt">
</span>an on-site<span style="letter-spacing: 0.1pt"> </span>inspection<span style="letter-spacing: 0.1pt"> </span>or other<span style="letter-spacing: 0.05pt">
</span>appropriate<span style="letter-spacing: 0.1pt"> </span>means.<span style="letter-spacing: 0.05pt"> </span>Many foreign<span style="letter-spacing: 0.05pt">
</span>regulatory<span style="letter-spacing: 0.1pt"> </span>bodies<span style="letter-spacing: 0.05pt"> </span>have similar<span style="letter-spacing: 0.1pt">
</span>approval<span style="letter-spacing: 0.05pt"> </span>requirements.<span style="letter-spacing: 0.15pt"> </span>In addition,<span style="letter-spacing: 0.05pt">
</span>such foreign<span style="letter-spacing: 0.05pt"> </span>trials<span style="letter-spacing: 0.1pt"> </span>would be subject<span style="letter-spacing: 0.05pt">
</span>to the<span style="letter-spacing: 0.05pt"> </span>applicable<span style="letter-spacing: 0.1pt"> </span>local<span style="letter-spacing: 0.05pt">
</span>laws of the<span style="letter-spacing: 0.05pt"> </span>foreign<span style="letter-spacing: 0.05pt"> </span>jurisdictions<span style="letter-spacing: 0.15pt">
</span>where the<span style="letter-spacing: 0.05pt"> </span>trials<span style="letter-spacing: 0.1pt"> </span>are conducted.<span style="letter-spacing: 0.05pt">
</span>There<span style="letter-spacing: 0.05pt"> </span>can be no assurance<span style="letter-spacing: 0.1pt"> </span>that<span style="letter-spacing: 0.05pt">
</span>the<span style="letter-spacing: 0.05pt"> </span>FDA<span style="letter-spacing: -0.05pt"> </span>or any other<span style="letter-spacing: 0.05pt">
</span>foreign<span style="letter-spacing: 0.05pt"> </span>regulatory<span style="letter-spacing: 0.1pt"> </span>authority<span style="letter-spacing: 0.1pt">
</span>will<span style="letter-spacing: 0.05pt"> </span>accept<span style="letter-spacing: 0.05pt"> </span>data from<span style="letter-spacing: 0.05pt">
</span>trials<span style="letter-spacing: 0.1pt"> </span>conducted<span style="letter-spacing: 0.05pt"> </span>outside<span style="letter-spacing: 0.05pt">
</span>of the<span style="letter-spacing: 0.05pt"> </span>United<span style="letter-spacing: 0.05pt"> </span>States<span style="letter-spacing: 0.05pt">
</span>or the<span style="letter-spacing: 0.05pt"> </span>applicable<span style="letter-spacing: 0.1pt"> </span>jurisdiction.<span style="letter-spacing: 0.15pt">
</span>If<span style="letter-spacing: 0.05pt"> </span>the<span style="letter-spacing: 0.05pt"> </span>FDA<span style="letter-spacing: -0.05pt">
</span>or any comparable foreign<span style="letter-spacing: 0.05pt"> </span>regulatory<span style="letter-spacing: 0.1pt"> </span>authority<span style="letter-spacing: 0.1pt">
</span>does not accept<span style="letter-spacing: 0.05pt"> </span>such data,<span style="letter-spacing: 0.05pt"> </span>it<span style="letter-spacing: 0.05pt">
</span>would result<span style="letter-spacing: 0.1pt"> </span>in the<span style="letter-spacing: 0.05pt"> </span>need for<span style="letter-spacing: 0.05pt">
</span>additional<span style="letter-spacing: 0.1pt"> </span>trials, which would be costly<span style="letter-spacing: 0.05pt">
</span>and time-consuming<span style="letter-spacing: 0.15pt"> </span>and delay<span style="letter-spacing: 0.05pt"> </span>aspects<span style="letter-spacing: 0.05pt">
</span>of our business<span style="letter-spacing: 0.05pt"> </span>plan,<span style="letter-spacing: 0.05pt"> </span>and which
may<span style="letter-spacing: 0.05pt"> </span>result<span style="letter-spacing: 0.1pt"> </span>in our product candidates<span style="letter-spacing: 0.1pt">
</span>not receiving<span style="letter-spacing: 0.1pt"> </span>approval<span style="letter-spacing: 0.05pt"> </span>or clearance<span style="letter-spacing: 0.1pt">
</span>for<span style="letter-spacing: 0.05pt"> </span>commercialization<span style="letter-spacing: 0.2pt"> </span>in the<span style="letter-spacing: 0.05pt">
</span>applicable<span style="letter-spacing: 0.1pt"> </span>jurisdiction.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: #231F20">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>We have received Fast Track designation
for one of our compounds and may seek such designation or breakthrough therapy and priority review for other compounds in the future.
Fast Track designation or breakthrough therapy designation may not actually lead to a faster FDA review and approval process.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 37; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->38<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">For some of our compounds, including ANAVEX<sup>&#174;</sup>2-73,
we hope to benefit from the FDA&#8217;s fast track and priority review programs. In February 2020, the FDA granted Fast Track designation
for the ANAVEX<sup>&#174;</sup>2-73 clinical development program for the treatment of Rett syndrome. Programs with Fast Track designation
may benefit from early and frequent communications with the FDA, potential priority review and the ability to submit a rolling
application for regulatory review. Fast Track designation applies to both the product candidate and the specific indication for
which it is being studied. If any of our compounds receive Fast Track designation but do not continue to meet the criteria for
Fast Track designation, or if our clinical trials are delayed, suspended or terminated, or put on clinical hold due to unexpected
adverse events or issues with clinical supply, we will not receive the benefits associated with the Fast Track program. Furthermore,
Fast Track designation does not change the standards for approval. The receipt of Fast Track designation for a compound may not
result in a faster development or regulatory review or approval process compared to products considered for approval under conventional
FDA procedures and does not assure ultimate approval by the FDA. In addition, even if any product candidate qualifies for Fast
Track designation, the FDA may later decide that the product candidates no longer meet the conditions for qualification or decide
that the time period for FDA review or approval will not be shortened. Fast Track designation alone does not guarantee qualification
for the FDA&#8217;s priority review procedures.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Under FDA policies, a compound is eligible
for priority review, or review within a six-month time frame from the time a complete NDA is accepted for filing, if the compound
provides a significant improvement compared to marketed drugs in the treatment, diagnosis or prevention of a disease. The FDA determines
whether a drug qualifies for Priority Review after an NDA for such drug is submitted to the FDA. Therefore, until NDAs are submitted
for our compounds, we cannot be assured that they will be granted Priority Review. Additionally, even if Priority Review is granted
for one of our compounds, the FDA does not always meet its six-month PDUFA goal date for Priority Review and the review process
is often extended by FDA requests for additional information or clarification.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We may seek Breakthrough Therapy designation
for one or more of our current or future compounds. Designation as a Breakthrough Therapy is largely within the discretion of the
FDA. Accordingly, even if we believe that a compound meets the criteria for designation as a Breakthrough Therapy, the FDA may
disagree and instead determine not to make such designation. In any event, the receipt of a Breakthrough Therapy designation for
a product candidate may not result in a faster development process, review or approval compared to candidate products considered
for approval under&#160;non-expedited&#160;FDA review procedures and does not assure ultimate approval by the FDA. In addition,
even if one or more compounds qualify as breakthrough therapies, the FDA may later decide that the product no longer meets the
conditions for qualification and revoke the designation.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Fast track or breakthrough therapy designation
for our compounds may not actually lead to a faster review process, and a delay in the review process or in the approval of our
compounds will delay revenue from their potential sales and will increase the capital necessary to fund these compound development
programs.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><b><i>We have received orphan drug designation for several of our
compounds, but we may be unable to maintain any benefits associated with orphan drug designation, including market exclusivity.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Under the Orphan Drug Act, the FDA may grant
orphan designation to a drug intended to treat a rare disease or condition or for which there is no reasonable expectation that
the cost of developing and making available in the United States a drug for a disease or condition will be recovered from sales
in the United States for that drug. If a product that has orphan drug designation subsequently receives the first FDA approval
for the indication for which it has such designation, the product is entitled to orphan product exclusivity, which means that the
FDA may not approve any other applications, including a full NDA, to market the same drug or biologic for the same indication for
seven years, except in limited circumstances, such as a showing of clinical superiority to the product with orphan drug exclusivity.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 38; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->39<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We have received orphan drug designation for
several of our compounds, but we may not be able to obtain or maintain orphan drug exclusivity in the United States for hose compounds.
We may not be the first to obtain marketing approval of any compound for which we have obtained orphan drug designation for the
orphan-designated indication due to the uncertainties associated with developing pharmaceutical products. In addition, exclusive
marketing rights in the United States may be limited if we seek FDA marketing approval for an indication broader than the orphan
designated indication. Additionally, any compound with orphan drug designation may lose such designation if the FDA later determines
that the request for designation was materially defective or if the manufacturer is unable to assure sufficient quantities of the
product to meet the needs of patients with the rare disease or condition. Even after an orphan drug is approved, the FDA can subsequently
approve the same drug with the same active moiety for the same condition if the FDA concludes that the later drug is clinically
superior in that it is shown to be safer, more effective or makes a major contribution to patient care.&#160;In addition, others
may obtain orphan drug exclusivity for products addressing the same diseases or conditions as products we are developing, thus
limiting our ability to compete in the markets addressing such diseases or conditions for a significant period of time.<b>&#160;</b><span style="color: black; background-color: white">Orphan
drug designation neither shortens the development time or regulatory review time of a drug nor gives the product candidate any
advantage in the regulatory review or approval process or entitles the product candidate to priority review.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>If we fail to demonstrate efficacy in
our non-clinical studies and clinical trials our future business prospects, financial condition and operating results will be materially
adversely affected.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The success of our research and development
efforts will be greatly dependent upon our ability to demonstrate potential drug compound efficacy in non-clinical studies, as
well as in clinical trials. Non-clinical studies involve testing potential drug compounds in appropriate non-human disease models
to demonstrate efficacy and safety. Regulatory agencies evaluate these data carefully before they will approve clinical testing
in humans. If certain non-clinical data reveals potential safety issues or the results are inconsistent with an expectation of
the potential drug compound&#8217;s efficacy in humans, the regulatory agencies may require additional more rigorous testing before
allowing human clinical trials. This additional testing will increase program expenses and extend timelines. We may decide to suspend
further testing on our potential drug compounds if, in the judgment of our management and advisors, the non-clinical test results
do not support further development.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Moreover, success in non-clinical testing and
early clinical trials does not ensure that later clinical trials will be successful, and we cannot be sure that the results of
later clinical trials will replicate the results of prior clinical trials and non-clinical testing. The clinical trial process
may fail to demonstrate that our potential drug compounds are safe for humans and effective for indicated uses. This failure would
cause us to abandon a drug candidate and may delay development of other potential drug compounds. Any delay in, or termination
of, our non-clinical testing or clinical trials will delay the filing of an IND and NDA with the FDA or the equivalent applications
with pharmaceutical regulatory authorities outside the United States and, ultimately, our ability to commercialize our potential
drug compounds and generate product revenues. In addition, we expect that our early clinical trials will involve small patient
populations. Because of the small sample size, the results of these early clinical trials may not be indicative of future results.
Also, the IND process may be extremely costly and may substantially delay the development of our potential drug compounds. Moreover,
positive results of non-clinical tests will not necessarily indicate positive results in subsequent clinical trials.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Following successful non-clinical testing,
potential drug compounds will need to be tested in a clinical development program to provide data on safety and efficacy prior
to becoming eligible for product approval and licensure by regulatory agencies. From the first human trial through to regulatory
approval can take many years and 10-12 years is not unusual for certain compounds.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If any of our future clinical development potential
drug compounds become the subject of problems, our ability to sustain our development programs will become critically compromised.
For example, efficacy or safety concerns may arise, whether or not justified, that could lead to the suspension or termination
of our clinical programs. Examples of problems that could arise include, among others:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">efficacy
    or safety concerns with the potential drug compounds, even if not justified;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">manufacturing
    difficulties or concerns;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">regulatory
    proceedings subjecting the potential drug compounds to potential recall;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif"></span></p>

<!-- Field: Page; Sequence: 39; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->40<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif"></span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">publicity
    affecting doctor prescription or patient use of the potential drug compounds;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">pressure
    from competitive products; or</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">introduction
    of more effective treatments.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Each clinical phase is designed to test attributes
of the drug and problems that might result in the termination of the entire clinical plan can be revealed at any time throughout
the overall clinical program. The failure to demonstrate efficacy in our clinical trials would have a material adverse effect on
our future business prospects, financial condition and operating results.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>If we do not obtain the support of qualified
scientific collaborators, our revenue, growth and profitability will likely be limited, which would have a material adverse effect
on our business.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We will need to establish relationships with
leading scientists and research institutions. We believe that such relationships are pivotal to establishing products using our
technologies as a standard of care for various indications. Additionally, although in discussion, there is no assurance that our
current research partners will continue to work with us or that we will be able to attract additional research partners. If we
are not able to establish scientific relationships to assist in our research and development, we may not be able to successfully
develop our potential drug compounds. If this happens, our business will be adversely affected.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>We may not be able to develop, market
or generate sales of our products to the extent anticipated. Our business may fail and investors could lose all their investment
in our Company.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Assuming that we are successful in developing
our potential drug compounds and receiving regulatory clearances to market our products, our ability to successfully penetrate
the market and generate sales of those products may be limited by a number of factors, including the following:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&#160;</p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">If
    our competitors receive regulatory approvals for and begin marketing similar products in the United States, the European Union,
    Japan and other territories before we do, greater awareness of their products as compared to ours will cause our competitive
    position to suffer;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">Information
    from our competitors or the academic community indicating that current products or new products are more effective or offer
    compelling other benefits than our future products could impede our market penetration or decrease our future market share;
    and</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 28px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;&#160;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">The
    pricing and reimbursement environment for our future products, as well as pricing and reimbursement decisions by our competitors
    and by payers, may have an effect on our revenues.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If this happens, our business will be adversely
affected.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>None of our potential drug compounds
may reach the commercial market for a number of reasons and our business may fail.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Successful research and development of pharmaceutical
products is high risk. Most products and development candidates fail to reach the market. Our success depends on the discovery
of new drug compounds that we can commercialize. It is possible that our products may never reach the market for a number of reasons.
They may be found ineffective or may cause harmful side-effects during non-clinical testing or clinical trials or fail to receive
necessary regulatory approvals. We may find that certain products cannot be manufactured at a commercial scale and, therefore,
they may not be economical to produce. Our potential products could also fail to achieve market acceptance or be precluded from
commercialization by proprietary rights of third parties. Our patents, patent applications, trademarks and other intellectual property
may be challenged, and this may delay or prohibit us from effectively commercializing our products. Furthermore, we do not expect
our potential drug compounds to be commercially available for a number of years, if at all. If none of our potential drug compounds
reach the commercial market, our business will likely fail and investors will lose all of their investment in our Company. If this
happens, our business will be adversely affected.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 40; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->41<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>If our competitors succeed in developing
products and technologies faster or that are more effective or with a better profile than our own, or if scientific developments
change our understanding of the potential scope and utility of our potential products, then our technologies and future products
may be rendered undesirable or obsolete.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We face significant competition from industry
participants that are pursuing technologies in similar disease states to those that we are pursuing and are developing pharmaceutical
products that are competitive with our products. Nearly all of our industry competitors have greater capital resources, larger
overall research and development staffs and facilities, and a longer history in drug discovery and development, obtaining regulatory
approval and pharmaceutical product manufacturing and marketing than we do. With these additional resources, our competitors may
be able to respond to the rapid and significant technological changes in the biotechnology and pharmaceutical industries faster
than we can. Our future success will depend in large part on our ability to maintain a competitive position with respect to these
technologies. Rapid technological development, as well as new scientific developments, may result in our products becoming obsolete
before we can recover any of the expenses incurred to develop them. For example, changes in our understanding of the appropriate
population of patients who should be treated with a targeted therapy like we are developing may limit the drug&#8217;s market potential
if it is subsequently demonstrated that only certain subsets of patients should be treated with the targeted therapy.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>We have advanced our research and development
efforts on the treatment of neurodegenerative and central nervous system, or CNS, disorders, a field that has seen very limited
success in product development.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">We have advanced our
research and development efforts on addressing neurodegenerative, neurodevelopmental and CNS disorders. Collectively, efforts by
pharmaceutical companies in the field of neurodegenerative,&#160;neurodevelopmental&#160;and CNS disorders have seen very limited
successes in product development. The development of neurodegenerative and CNS therapies presents unique challenges, including
an imperfect understanding of the biology, the presence of the blood brain barrier, or BBB, that can restrict the flow of drugs
to the brain, a frequent lack of translatability of preclinical study results in subsequent clinical trials and dose selection,
and the product candidate having an effect that may be too small to be detected using the outcome measures selected in clinical
trials or if the outcomes measured do not reach statistical significance.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Our reliance on third parties, such as
university laboratories, contract manufacturing organizations and contract or clinical research organizations, may result in delays
in completing, or a failure to complete, non-clinical testing or clinical trials if they fail to perform under our agreements with
them or non-compliance with regulations.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In the course of product development, we may
engage university laboratories, other biotechnology companies or contract or clinical manufacturing organizations to manufacture
drug material for us to be used in non-clinical and clinical testing and contract research organizations to conduct and manage
non-clinical studies and clinical trials. If we engage these organizations to help us with our non-clinical and clinical programs,
many important aspects of this process have been and will be out of our direct control. If any of these organizations we may engage
in the future fail to perform their obligations under our agreements with them or fail to perform non-clinical testing and/or clinical
trials in a satisfactory manner, we may face delays in completing our clinical trials, as well as commercialization of any of our
potential drug compounds. Furthermore, any loss or delay in obtaining contracts with such entities may also delay the completion
of our clinical trials, regulatory filings and the potential market approval of our potential drug compounds.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 41; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->42<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In addition, any of these third parties may
engage in misconduct or other improper activities, including non-compliance with regulatory standards and requirements. Misconduct
by these parties could include intentional, reckless and/or negligent conduct or disclosure of unauthorized activities to us that
violate the regulations of any regulatory authorities, including those laws requiring the reporting of true, complete and accurate
information to such authorities; healthcare fraud and abuse laws and regulations in the United States and abroad; or laws that
require the reporting of financial information or data accurately. It is not always possible to identify and deter misconduct by
employees and other third parties, and the precautions we take to detect and prevent this activity may not be effective in controlling
unknown or unmanaged risks or losses or in protecting us from governmental investigations or other actions or lawsuits stemming
from a failure to comply with these laws or regulations.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>If we fail to compete successfully with
respect to partnering, licensing, mergers, acquisitions, joint venture and other collaboration opportunities, we may be limited
in our ability to research and develop our potential drug compounds.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Our competitors compete with us to attract
established biotechnology and pharmaceutical companies or organizations for partnering, licensing, mergers, acquisitions, joint
ventures or other collaborations. Collaborations include contracting with academic research institutions for the performance of
specific scientific testing. If our competitors successfully enter into partnering arrangements or license agreements with academic
research institutions, we will then be precluded from pursuing those specific opportunities. Since each of these opportunities
is unique, we may not be able to find a substitute. Other companies have already begun many drug development programs, which may
target diseases that we are also targeting, and have already entered into partnering and licensing arrangements with academic research
institutions, reducing the pool of available opportunities.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Universities and public and private research
institutions also compete with us. While these organizations primarily have educational or basic research objectives, they may
develop proprietary technology and acquire patent applications and patents that we may need for the development of our potential
drug compounds. In some instances, we will attempt to license this proprietary technology, if available. These licenses may not
be available to us on acceptable terms, if at all. If we are unable to compete successfully with respect to acquisitions, joint
venture and other collaboration opportunities, we may be limited in our ability to develop new products.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>The use of any of our products in clinical
trials may expose us to liability claims, which may cost us significant amounts of money to defend against or pay out, causing
our business to suffer.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The nature of our business exposes us to potential
liability risks inherent in the testing, manufacturing and marketing of our products. We currently have one drug compound in clinical
trials, however, when any of our products enter clinical trials or become marketed products, they could potentially harm people
or allegedly harm people possibly subjecting us to costly and damaging product liability claims. Some of the patients who participate
in clinical trials are already ill when they enter a trial or may intentionally or unintentionally fail to meet the exclusion criteria.
The waivers we obtain may not be enforceable and may not protect us from liability or the costs of product liability litigation.
Although we intend to obtain product liability insurance, which we believe is adequate, we are subject to the risk that our insurance
will not be sufficient to cover claims. The insurance costs along with the defense or payment of liabilities above the amount of
coverage could cost us significant amounts of money and management distraction from other elements of the business, causing our
business to suffer.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>If our information systems or data, or
those of third parties upon whom we rely, are or were compromised, our business may be adversely affected.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In the course of our business, we, or third
parties upon which we rely, may gather, collect, receive, use, transmit, store/retain or dispose of data and confidential information
(such as confidential employee information or health-related data), sensitive data, intellectual property and trade secrets.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">Cyberattacks,
malicious internet-based activity, online and offline fraud and other similar activities threaten the confidentiality, integrity,
and availability of our sensitive information and information technology systems, and those of the third parties upon which we
rely. We, and the third parties upon which we may rely, may be subject to a variety of these evolving threats.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"></p>

<!-- Field: Page; Sequence: 42; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->43<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">Although we
endeavor to protect confidential information through the implementation of security technologies, processes and procedures, it
is possible that an individual or group could defeat security measures and access sensitive information about our business and
employees. <span style="color: black">The existence of a remote workforce also poses increased risks to our information technology
systems and data, as more of our employees work from home, utilizing network connections outside our premises. </span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Any misappropriation, loss or other unauthorized
disclosure of confidential information gathered, stored or used by us or by third parties on our behalf, could have a material
impact on the operation of our business, including damaging our reputation with our employees, third parties and investors. We
could also incur significant costs implementing additional security measures and organizational changes, implementing additional
protection technologies, training employees or engaging consultants.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="color: black">Our
contracts with third parties upon which we may rely, may not contain limitations of liability, and even where they do, there can
be no assurance that limitations of liability in our contracts are sufficient to protect us from liabilities, damages, or claims
related to our data privacy and security obligations. </span>In addition, we could incur increased litigation as a result of any
potential cyber-security breach and<span style="color: black"> our insurance coverage may not be adequate or sufficient in type
or amount to protect us from or to mitigate liabilities arising out of our privacy and security practices.</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We are not aware that we have experienced any
material misappropriation, loss or other unauthorized disclosure of confidential or personally identifiable information as a result
of a cyber-security breach or other act, however, a cyber-security breach or other act and/or disruption to our information technology
systems could have a material adverse effect on our business, prospects, financial condition or results of operations.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Even if we receive regulatory approval
for one or more compounds, we will be subject to continuing regulatory obligations and ongoing regulatory review, which may result
in significant additional expense. Additionally, our compounds, if approved, could be subject to labeling and other restrictions
on marketing or withdrawal from the market, and we may be subject to penalties, if we fail to comply with regulatory requirements
or if we experience unanticipated problems with our compounds, when and if any of them are approved. </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Following potential approval of any our compounds,
the FDA may impose significant restrictions on a drug&#8217;s indicated uses or marketing or require potentially costly and time-consuming
post-approval studies, post-market surveillance or clinical trials to monitor the safety and efficacy of the drug. The FDA may
also require a Risk Evaluation and Mitigation Strategy (&#8220;REMS&#8221;) as a condition of approval of one or more of our compounds,
which could include requirements for a medication guide, physician communication plans or additional elements to ensure safe use
of the drug. Additional REMS elements may include restricted distribution methods, patient registries and other risk minimization
tools.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In addition, if the FDA or a comparable foreign
regulatory authority approves one or more of our compounds, the manufacturing processes, labeling, packaging, distribution, adverse
event reporting, storage, advertising, promotion, import, export and recordkeeping for the approved drug will be subject to additional
and potentially extensive ongoing regulatory requirements. These requirements include submissions of safety and other post-marketing
information and reports, establishment registration, as well as continued compliance with cGMPs and GCP requirements for any clinical
trials that we conduct post-approval. Later discovery of previously unknown problems with our products, including adverse events
of unanticipated severity or frequency, or with our third-party manufacturers or manufacturing processes, or failure to comply
with regulatory requirements, may result in, among other things:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">restrictions
    on the marketing or manufacturing of our products, withdrawal of the product from the market or voluntary or mandatory product
    recalls; </span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: 0.5in"></p>

<!-- Field: Page; Sequence: 43; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->44<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: 0.5in"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: 0.5in">&#160;</p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">fines,
    restitutions, disgorgement of profits or revenues, warning letters, untitled letters or holds on clinical trials; </span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">restrictions
    on product distribution or use, or requirements to conduct post-marketing studies or clinical trials; </span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">product
    seizure or detention, or refusal to permit the import or export of our products;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">injunctions
    or the imposition of civil or criminal penalties; and</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">refusal
    by the FDA to approve pending applications or supplements to approved applications filed by us or suspension or revocation
    of approvals.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The occurrence of any event or penalty described
above may limit our ability to commercialize our compounds and generate revenue, and could require us to expend significant time
and resources in response or generate negative publicity.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If any of our compounds are approved, our product
labeling, advertising and promotion will also be subject to regulatory requirements and ongoing regulatory review. The FDA strictly
regulates the promotional claims that may be made about drug products. In particular, a drug may not be promoted for uses that
are not approved by the FDA as reflected in the drug&#8217;s approved labeling. If we receive marketing approval for a compound,
physicians may nevertheless lawfully prescribe it to their patients in a manner that is inconsistent with the approved label. While
the FDA recently clarified that mere knowledge that a physician is prescribing an approved drug for off label use is not sufficient
to constitute unlawful off-label promotion, if we are found to have actively promoted such off label uses, we may become subject
to significant liability under the FDCA. The federal government has levied large civil and criminal fines against companies for
alleged improper promotion and has enjoined several companies from engaging in off-label promotion. Additionally, promotion for
off label uses could result in significant liability under the False Claims Act. The FDA has also requested that companies enter
into consent decrees or permanent injunctions under which specified promotional conduct is changed or curtailed.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The FDA&#8217;s and other regulatory authorities&#8217;
policies are subject to change at any time, and additional government regulations may be enacted that could prevent, limit or delay
regulatory approval of our compounds. If we are unable to timely adapt to changes in existing requirements or the adoption of new
requirements or policies, or if we are not able to maintain regulatory compliance post-marketing, we may lose any marketing approval
that we may have obtained, and we may not achieve or sustain profitability.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Finally, we cannot predict the likelihood,
nature or extent of government regulation that may arise from future legislation or administrative or executive action, either
in the United States or abroad. It is difficult to predict how any such legislative, administrative or executive actions will be
implemented, and the extent to which they will impact the FDA&#8217;s ability to exercise its regulatory authority. If these legislative
or executive actions impose constraints on the FDA&#8217;s ability to engage in oversight and implementation activities in the
normal course, our business may be negatively impacted.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>We receive&#160;Australian&#160;government
research and development income&#160;tax&#160;incentive refunds. If our research and development expenditures are not deemed to
be eligible for the refund, proposed modifications to the&#160;tax&#160;incentive program are enacted, or the&#160;tax&#160;incentive
program is discontinued by the&#160;Australian&#160;government, it could have a negative effect on our future cash flows and the
funding of future research and development projects.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Our subsidiary, Anavex Australia Pty Ltd.,
is incorporated in Australia where we are currently engaged in research and development activities for ANAVEX<sup>&#174;</sup>2-73
and ANAVEX<sup>&#174;</sup>3-71. Our subsidiary is eligible to participate in the&#160;Australian&#160;Federal Government&#8217;s
Research and Development&#160;Tax&#160;Incentive program, under which the government provides a cash refund for a portion of eligible
research and development expenditures (currently 43.5% to 48.5% depending on the entity&#8217;s corporate tax rate) by small&#160;Australian&#160;entities,
which are defined as&#160;Australian&#160;entities with less than $20 million (Australian) in revenue.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 44; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->45<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Research and Development&#160;Tax&#160;Incentive
refund is offered by the&#160;Australian&#160;federal government for eligible research and development purposes based on the filing
of an annual application. As part of this program, our subsidiary applied for and received cash refunds from the&#160;Australian&#160;Taxation
Office, or the ATO, for a percentage of the research and development costs expended by our subsidiary in Australia. Since the fiscal
year ended September 30, 2015, we have been receiving Research and Development&#160;Tax&#160;Incentive refunds related to research
and development expenditures made.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Certain research and development expenses incurred
outside of Australia are also eligible for the&#160;Australian&#160;research and development&#160;tax&#160;incentive program, provided
we obtain an Advance Overseas Finding from AusIndustry, a division of the Australian Government&#8217;s Department of Industry,
Innovation and Science (&#8220;AusIndustry&#8221;).&#160;To receive an Advance Overseas Finding, the expenses must have been for
eligible research and development activities, as determined by AusIndustry, and the expenditures must have a scientific link to
the&#160;Australian&#160;activities, be unable to be conducted in Australia and the total actual and reasonably anticipated overseas
costs must be expected to be less than the total actual and reasonably anticipated expenditures for activities conducted within
Australia, as determined by AusIndustry at the time of application for an Advance Overseas Finding (&#8220;OSF&#8221;).</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">This OSF binds both
AusIndustry and the Commissioner of Taxation for three income years. However, for compliance purposes, specific issue guidance
jointly issued by AusIndustry and the ATO in 2014 provides that an OSF can apply for the duration of the overseas activity provided
the activities are not new or materially different then the activities described in the OSF. Currently, the Company is outside
of the binding three-year period with respect to OSF applicable to some of its programs being claimed in Australia.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">To the extent that some or all of our research
and development expenditures are deemed to be &#8220;ineligible,&#8221; then our refunds may decrease or be eliminated. In addition,
the&#160;Australian&#160;government may in the future modify the requirements of, reduce the amounts of the refunds available under,
or discontinue the Research and Development&#160;Tax&#160;Incentive program. Any such change to our anticipated refunds or change
to the Research and Development&#160;Tax&#160;Incentive program would have a negative effect on our future cash flows.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>A variety of risks are associated with
operating our business internationally which could materially adversely affect our business.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="color: black">We are presently
conducting clinical development solely in Australia, </span>United Kingdom, The Netherlands, Germany and Canada<span style="color: black">
and may choose to conduct additional international and U.S. clinical trials in the future. Additionally, while we have not taken
any steps to enter into any non-U.S. markets, we may do so in the future. Accordingly, we are subject to risks related to operating
in foreign countries, including:</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">different
    standards of care in various countries that could complicate the evaluation of our product candidates;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">different
    United States and foreign drug import and export rules;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">reduced
    protection for intellectual property rights in certain countries;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">unexpected
    changes in tariffs, trade barriers and regulatory requirements;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">economic
    weakness, including inflation, or political instability in particular foreign economies and markets;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">compliance
    with tax, employment, immigration, and labor laws for employees living or traveling abroad;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">compliance
    with the FCPA and other anti-corruption and anti-bribery laws;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif"></span></p>

<!-- Field: Page; Sequence: 45; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->46<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif"></span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">foreign
    taxes, including withholding of payroll taxes;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">foreign
    currency fluctuations, which could result in increased operating expenses and reduced revenue, and other obligations incident
    to doing business in another country;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">workforce
    uncertainty in countries where labor unrest is more common than in the United States;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="width: 100%; font-size: 10pt">
<tr style="vertical-align: top">
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; font-family: Times New Roman, Times, Serif; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">production
    shortages resulting from any events affecting raw material supply or manufacturing capabilities abroad;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">different payor
    reimbursement regimes, governmental payors or patient self-pay systems and price controls;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">potential liability
    resulting from development work conducted by foreign partners;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">business interruptions
    resulting from natural disasters, outbreaks of contagious diseases, such as COVID-19, or geopolitical actions, including war
    and terrorism, or systems failure including cybersecurity breaches; and</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">compliance with
    evolving and expansive foreign regulatory requirements, including data privacy laws (such as the GDPR).</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Additionally, in connection with the ongoing
conflict between Russia and Ukraine, the U.S. government and European Union countries have imposed enhanced export controls on
certain products and sanctions on certain industry sectors and parties in Russia. The U.S. government has also indicated it will
consider imposing additional sanctions and other similar measures in the near future. Although we do not currently conduct any
clinical trials in Russia or Ukraine, further escalation of geopolitical tensions could have a broader impact that expands into
other markets where we do business or conduct certain research and development operations, which could adversely affect our business,
our supply chain for our product candidates, our collaborators or our ability to carry out our clinical trials.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="background-color: white"><b><i>Our
ability to use our net operating loss (&#8220;NOL&#8221;) carryforwards and certain tax credit carryforwards may be subject to
limitation.</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">As of September 30, 2023, we had approximately
$126.3 million of U.S. federal and $192.0 million of state and local NOL carryforwards. We had approximately $12.9 million of NOL
carryforwards in Australia as of the same period. Our NOL carryforwards are subject to review and possible adjustment by the U.S.
and state tax authorities. In addition, under Sections 382 and 383 of the Code and corresponding provisions of state law, if a
corporation undergoes an &#8220;ownership change,&#8221; which is generally defined as a greater than 50% change (by value) in
its equity ownership over a three-year period, the corporation&#8217;s ability to use its pre-change NOL carryforwards and research
and development credits to offset its post-change income may be limited. This could limit the amount of NOLs or research and development
credit carryforwards that we can utilize annually to offset future taxable income or tax liabilities. Subsequent ownership changes
and changes to the U.S. tax rules in respect of the utilization of NOLs and research and development credits carried forward may
further affect the limitation in future years. In addition, at the state level, there may be periods during which the use of NOLs
is suspended or otherwise limited, which could accelerate or permanently increase state taxes owed.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We conducted a Section 382 study during the
year ended September 30, 2021 and determined that, during the year ended September 30, 2015, there was a change in ownership which
resulted in $25.8 million of federal NOLs being subject to an annual limitation. During the year ended September 30, 2021, we reduced
our federal NOLs by $12.1 million and our research and development tax credit carryforwards by $0.8 million, which are the amount
of tax assets that will expire unutilized pursuant to the Section 382 study. This resulted in a reduction of $2.5 million of NOLs
and $0.8 million of research and development credits and a corresponding reduction in the valuation allowance of $3.3 million,
which was recorded in the 2021 fiscal year. Subsequent ownership changes in future years could trigger additional limitations of
our NOLs. During the year ended September 30, 2023 and 2022, we determined that there were no changes in ownership pursuant to
Section 382.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 46; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->47<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>We are subject to healthcare laws and
regulations which may require substantial compliance efforts and could expose us to criminal sanctions, civil and administrative
penalties, contractual damages, reputational harm and diminished profits and future earnings, among other penalties.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Healthcare providers, physicians and others
will play a primary role in the recommendation and prescription of our products, if approved. Our arrangements with such persons
and third-party payors and our general business operations will expose us to broadly applicable fraud and abuse and other healthcare
laws and regulations that may constrain the business or financial arrangements and relationships through which we research, market,
sell and distribute our drugs, if we obtain marketing approval. Restrictions under applicable U.S. federal, state and foreign healthcare
laws and regulations include, but are not limited to, the following:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the U.S. federal
    Anti-Kickback Statute, which prohibits, among other things, persons or entities from knowingly and willfully soliciting, offering,
    receiving or providing remuneration, including any kickback, bribe or rebate, directly or indirectly, in cash or in kind,
    to induce or reward, or in return for, either the referral of an individual for, or the purchase or lease, order or recommendation
    of, any item, good, facility or service, for which payment may be made under federal healthcare programs such as Medicare
    and Medicaid;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">U.S. federal civil
    and criminal false claims laws and civil monetary penalties laws, including the civil False Claims Act, which impose criminal
    and civil penalties, including those from civil whistleblower or qui tam actions, against individuals or entities for, among
    other things, knowingly presenting, or causing to be presented, claims for payment that are false or fraudulent or making
    a false statement to avoid, decrease, or conceal an obligation to pay money to the federal government;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">The Stark Law prohibits
    a physician from making referrals for certain &#8220;designated health services&#8221; payable by Medicare to an entity in
    which the physician or an immediate family member of such physician has an ownership or investment interest or with which
    the physician has entered into a compensation arrangement, unless a statutory exception applies. There are a number of exceptions
    to the Stark Law. Such exceptions permit certain payments and arrangements that, although they would otherwise potentially
    implicate the Stark Law, are not treated as a violation under the same if the requirements of the specific exceptions are
    met.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">HIPAA, which among
    other things, created additional federal criminal statutes that impose criminal and civil liability for, such actions as executing
    or attempting to execute a scheme to defraud any healthcare benefit program or knowingly and willingly falsifying, concealing
    or covering up a material fact or making false statements relating to healthcare matters;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">The privacy and
    security provisions of HIPAA, which impose certain requirements on covered entities and their business associates, including
    mandatory contractual terms, with respect to safeguarding the privacy, security and transmission of individually identifiable
    health information;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">U.S. federal transparency
    requirements under the Physician Payments Sunshine Act, enacted as part of the Affordable Care Act that require applicable
    manufacturers of covered drugs, devices, biologics and medical supplies for which payment is available under Medicare, Medicaid
    or the Children&#8217;s Health Insurance Program, with specific exceptions, to track and annually report to CMS payments and
    other transfers of value provided to physicians, certain other healthcare providers (such as physicians assistants and nurse
    practitioners),and teaching hospitals, as well as ownership and investment interests held by physicians or their immediate
    family members; and</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<!-- Field: Page; Sequence: 47; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->48<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">analogous state
    or foreign laws and regulations, such as state anti-kickback and false claims laws, which may apply to items or services reimbursed
    by any third-party payor, including commercial insurers, state marketing and/or transparency laws applicable to manufacturers
    that may be broader in scope than the federal requirements, state laws that require biopharmaceutical companies to comply
    with the biopharmaceutical industry&#8217;s voluntary compliance guidelines and the relevant compliance guidance promulgated
    by the federal government and state laws governing the privacy and security of health information in certain circumstances,
    many of which differ from each other in significant ways and may not have the same effect as HIPAA, thus complicating compliance
    efforts.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Ensuring that our business arrangements with
third parties comply with applicable healthcare laws and regulations will likely be costly. It is possible that governmental authorities
will conclude that our business practices do not comply with current or future statutes, regulations or case law involving applicable
fraud and abuse or other healthcare laws and regulations. If our operations were found to be in violation of any of these laws
or any other governmental regulations that may apply to us, we may be subject to significant civil, criminal and administrative
penalties, damages, fines, disgorgement, imprisonment, possible exclusion from government funded healthcare programs, such as Medicare
and Medicaid, contractual damages, reputational harm, diminished profits and future earnings and curtailment of our operations,
any of which could substantially disrupt our operations. If the physicians or other providers or entities with whom we expect to
do business are found not to be in compliance with applicable laws, they may be subject to criminal, civil or administrative sanctions,
including exclusions from government funded healthcare programs. We may incur significant costs achieving and maintaining compliance
with applicable federal and state privacy, security, and fraud laws. Any action against us for violation of these laws, even if
we successfully defend against it, could cause us to incur significant legal expenses and divert our attention from the operation
of our business.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>We expect current and future legislation
affecting the pharmaceutical industry, including drug pricing reform, to impact our business generally, which could adversely affect
our business operations. </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In the United States, there have been, and
continue to be proposed and enacted legislation at the federal and state levels designed to, among other things, bring more transparency
to drug pricing, review the relationship between pricing and manufacturer patient programs, reduce the cost of drugs under Medicare,
and reform government program reimbursement methodologies for drugs. For example, in July 2021, the Biden administration released
an executive order, &#8220;Promoting Competition in the American Economy,&#8221; with multiple provisions aimed at prescription
drugs. In response to Biden&#8217;s executive order, on September 9, 2021, HHS released a Comprehensive Plan for Addressing High
Drug Prices that outlines principles for drug pricing reform and sets out a variety of potential legislative policies that Congress
could pursue as well as potential administrative actions HHS can take to advance these principles. In addition, the IRA, among
other things, (1) directs HHS to negotiate the price of certain single-source drugs and biologics covered under Medicare and (2)
imposes rebates under Medicare Part B and Medicare Part D to penalize price increases that outpace inflation. These provisions
will take effect progressively starting in fiscal year 2023, although they may be subject to legal challenges. It is currently
unclear how the IRA will be implemented but is likely to have a significant impact on the pharmaceutical industry. If any of our
products are subject to such negotiation, we may lose a significant amount of the revenues expected during the full life cycle
of these products. Further, the Biden administration released an additional executive order on October 14, 2022, directing HHS
to submit a report within 90 days on how the Center for Medicare and Medicaid Innovation can be further leveraged to test new models
for lowering drug costs for Medicare and Medicaid beneficiaries. We&#160;expect that additional U.S. federal healthcare reform
measures will be adopted in the future, any of which could limit the amounts that the U.S. federal government will pay for healthcare
products and services, which could result in reduced demand for our product candidates or additional pricing pressures.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>The coverage and reimbursement status
of newly approved products is uncertain. Failure to obtain or maintain adequate coverage and reimbursement for our product candidates,
if approved, could limit our ability to market those products and decrease our ability to generate product revenue.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 48; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->49<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Significant uncertainty exists as to the coverage
and reimbursement status of any compound for which we may seek regulatory approval. Sales in the United States will depend in part
on the availability of sufficient coverage and adequate reimbursement from third-party payors, which include government health
programs such as Medicare, Medicaid, CHIP, TRICARE and the Veterans Administration, as well as managed care organizations and private
health insurers. Prices at which we or our customers seek reimbursement for our therapeutic compounds can be subject to challenge,
reduction or denial by payors.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The process for determining whether a payor
will provide coverage for a product is typically separate from the process for setting the reimbursement rate that the payor will
pay for the product. A payor&#8217;s decision to provide coverage for a product does not imply that an adequate reimbursement rate
will be available. Additionally, in the United States there is no uniform policy among payors for coverage or reimbursement. Third-party
payors often rely upon Medicare coverage policy and payment limitations in setting their own coverage and reimbursement policies,
but also have their own methods and approval processes. Therefore, coverage and reimbursement for products can differ significantly
from payor to payor. If coverage and adequate reimbursement are not available, or are available only at limited levels, successful
commercialization of, and obtaining a satisfactory financial return on, any product we develop may not be possible.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="color: black">Third-party payors
are increasingly challenging the price and examining the medical necessity and cost-effectiveness of medical products and services,
in addition to their safety and efficacy. In order to obtain coverage and reimbursement for any product that might be approved
for marketing, we may need to conduct expensive studies in order to demonstrate the medical necessity and cost-effectiveness of
any products, which would be in addition to the costs expended to obtain regulatory approvals. Third-party payors may not consider
our compounds to be medically necessary or cost-effective compared to other available therapies, or the rebate percentages required
to secure favorable coverage may not yield an adequate margin over cost or may not enable us to maintain price levels sufficient
to realize an appropriate return on our investment in drug development. </span>Additionally, we or our collaborators may develop
companion diagnostic tests for use with our product candidates. Companion diagnostic tests require coverage and reimbursement separate
and apart from the coverage and reimbursement for their companion pharmaceutical or biological products. Similar challenges to
obtaining coverage and reimbursement, applicable to pharmaceutical or biological products, will apply to companion diagnostics.
<span style="color: black">Our inability to promptly obtain coverage and adequate reimbursement from third-party payors for the
product candidates, and for us or our collaborators to obtain coverage and adequate reimbursement for related companion diagnostic
tests that may be developed, could have a material and adverse effect on our business, financial condition, results of operations
and prospects.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Risks Related to our Common Stock</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>A decline in the price of our common
stock could affect our ability to raise further working capital and adversely impact our operations and would severely dilute existing
or future investors if we were to raise funds at lower prices.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">A prolonged decline in the price of our common
stock could result in a reduction in our ability to raise capital. Because our operations have been financed through the sale of
equity securities, a decline in the price of our common stock could be especially detrimental to our continued operations. Any
reduction in our ability to raise equity capital in the future would force us to reallocate funds from other planned uses and would
have a significant negative effect on our business plans and operations, including our ability to develop new products and continue
our current operations. If our stock price declines, there can be no assurance that we can raise additional capital or generate
funds from operations sufficient to meet our obligations. We believe the following factors could cause the market price of our
common stock to continue to fluctuate widely and could cause our common stock to trade at a price below the price at which you
purchase your shares of common stock:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">actual or anticipated
    variations in our quarterly operating results;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">announcements of
    new services, products, acquisitions or strategic relationships by us or our competitors;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif"></span></p>

<!-- Field: Page; Sequence: 49; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->50<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">changes in accounting
    treatments or principles;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">changes in earnings
    estimates by securities analysts and in analyst recommendations; and</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">general political,
    economic, regulatory and market conditions.</span></td></tr>
</table>
<p style="font: 12pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The market price for our common stock may also
be affected by our ability to meet or exceed expectations of analysts or investors. Any failure to meet these expectations, even
if minor, could materially adversely affect the market price of our common stock.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>If we issue additional shares of common
stock in the future, it will result in the dilution of our existing stockholders and may cause the share price of our common stock
to fall.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We have 200,000,000 shares of common stock
authorized for issuance and we also have 10,000,000 shares of preferred stock authorized. Our Board of Directors has the authority
to issue additional shares of preferred and common stock up to the authorized capital stated in the articles of incorporation.
Our Board of Directors may choose to issue some or all such shares of common stock to acquire one or more businesses or to provide
additional financing in the future. The issuance of any such shares of common stock will result in a reduction of the book value
or market price of the outstanding shares of our common stock. If we do issue any such additional shares of common stock, such
issuance also will cause a reduction in the proportionate ownership and voting power of all other stockholders. Further, any such
issuance may result in a change of control of our corporation. In the event we do issue or sell additional shares of common or
preferred stock, it may result in stockholder dilution and may cause our share price to fall.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Our stock price has been volatile and
may be volatile in the future.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Our stock price has been volatile at certain
times historically, and may be volatile in the future. We may incur rapid and substantial increases or decreases in our stock price
in the foreseeable future that are do not coincide in timing with the disclosure of news or developments by us. The stock market
in general, and the market for biotechnology and pharmaceutical companies in particular, has experienced extreme volatility that
has often been unrelated to the operating performance of particular companies. The market price for our common stock may be influenced
by many factors, including the following:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 24px; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">announcements of
    new data, clinical trial results or those of companies that are perceived to be similar to us;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">announcements related
    to any delays in any preclinical or clinical trials related to our products;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">announcements related
    to our products&#8217; ability to demonstrate efficacy or an acceptable safety profile of our product candidates or similar
    announcements by companies that are perceived to be similar to us;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">our ability to meet
    or exceed expectations of analysts or investors;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">news that the number
    of patients required for clinical trials for our drug candidates may be larger than we anticipate, enrollment in these clinical
    trials may be slower than we anticipate, participants may drop out of these clinical trials at a higher rate than we anticipate
    or the duration of these clinical trials may be longer than we anticipate;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">actions taken by
    regulatory agencies with respect to our product candidates or the progress of our clinical trials, including with respect
    to any fast track or orphan drug designations;</span></td></tr>
</table>

<p style="margin: 0">&#160;</p>

<p style="margin: 0"></p>

<!-- Field: Page; Sequence: 50; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->51<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="margin: 0">&#160;</p>

<p style="margin: 0"></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%">
<tr style="vertical-align: top">
    <td style="line-height: 115%; width: 24px"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%; width: 24px"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">announcements of
    significant acquisitions, strategic partnerships, joint ventures or capital commitments by us, our strategic collaboration
    partners or our competitors;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">grants awarded to
    us or companies that are perceived to be similar to us from outside entities;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">variations in our
    financial results or those of companies that are perceived to be similar to us;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">trading volume of
    our common stock;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">developments concerning
    our collaborations or partners;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the impact of the
    COVID-19 outbreak and its effect on us;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the perception of
    the biotechnology or pharmaceutical industries by the public, legislatures, regulators and the investment community;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">developments or
    disputes concerning intellectual property rights;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">significant lawsuits,
    including patent or stockholder litigation;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">our ability or inability
    to raise additional capital and the terms on which we raise it;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">sales of our common
    stock by us or our stockholders;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">declines in the
    market prices of stocks generally or of companies that are perceived to be similar to us; and</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: top">
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">general economic,
    industry and market conditions.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In addition, companies trading in the stock
market in general, and The Nasdaq Capital Market in particular, have experienced extreme price and volume fluctuations that have
often been unrelated or disproportionate to the operating performance of these companies. These broad market and industry factors
may seriously harm the market price of our common stock, regardless of our operating performance. In the past, following periods
of volatility in the market, securities class-action litigation has often been instituted against companies. Such litigation, if
instituted against us, could result in substantial costs and diversion of management&#8217;s attention and resources, which could
materially and adversely affect our business, financial condition, results of operations and growth prospects. There can be no
guarantee that our stock price will remain at current prices.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Our common stock may become the target
of a &#8220;short squeeze.&#8221;</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Securities of certain companies have experienced
significant and extreme volatility in stock price due to short sellers of shares of common stock, known as a &#8220;short squeeze.&#8221;
These short squeezes have caused extreme volatility in those companies and in the market and have led to the price per share of
those companies to trade at a significantly inflated rate that is disconnected from the underlying value of the company. Many investors
who have purchased shares in those companies at an inflated rate face the risk of losing a significant portion of their original
investment as the price per share has declined steadily as interest in those stocks have abated. There can be no assurance that
we will not, in the future be, a target of a short squeeze, and you may lose a significant portion or all of your investment if
you purchase our shares at a rate that is significantly disconnected from our underlying value.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 51; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->52<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>If we fail to maintain an effective system
of internal control over financial reporting, we may not be able to accurately report our financial results or prevent fraud. As
a result, stockholders could lose confidence in our financial and other public reporting, which would harm our business and the
trading price of our common stock.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Pursuant to Section 404 of the Sarbanes-Oxley
Act, our management is required to report upon the effectiveness of our internal control over financial reporting. We cannot assure
you that there will not be material weaknesses or significant deficiencies in our internal control over financial reporting in
the future. Any failure to maintain internal control over financial reporting could severely inhibit our ability to accurately
report our financial condition, results of operations or cash flows. If we are unable to conclude that our internal control over
financial reporting is effective, or if our independent registered public accounting firm determines we have a material weakness
or significant deficiency in our internal control over financial reporting, investors may lose confidence in the accuracy and completeness
of our financial reports, the market price of our common stock could decline, and we could be subject to sanctions or investigations
by the Nasdaq Stock Market, the SEC or other regulatory authorities. Failure to remedy any material weakness in our internal control
over financial reporting, or to implement or maintain other effective control systems required of public companies, could also
restrict our future access to the capital markets.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Our disclosure controls and procedures
may not prevent or detect all errors or acts of fraud.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We are subject to the periodic reporting requirements
of the Exchange Act. We designed our disclosure controls and procedures to reasonably assure that information we must disclose
in reports we file or submit under the Exchange Act is accumulated and communicated to management, and recorded, processed, summarized
and reported within the time periods specified in the rules and forms of the SEC. We believe that any disclosure controls and procedures
or internal controls and procedures, no matter how well-conceived and operated, can provide only reasonable, not absolute, assurance
that the objectives of the control system are met. These inherent limitations include the realities that judgments in decision-making
can be faulty, and that breakdowns can occur because of simple error or mistake. For example, our directors or executive officers
could inadvertently fail to disclose a new relationship or arrangement causing us to fail to make a required related party transaction
disclosure. Additionally, controls can be circumvented by the individual acts of some persons, by collusion of two or more people
or by an unauthorized override of the controls. Accordingly, because of the inherent limitations in our control system, misstatements
due to error or fraud may occur and not be detected.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Risks Related to our Intellectual Property
</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>If we are unable to obtain and maintain
sufficient intellectual property protection for our product candidates, or if the scope of the intellectual property protection
obtained is not sufficiently broad, our competitors could develop and commercialize product candidates similar or identical to
ours, and our ability to successfully commercialize our product candidates that we may pursue may be impaired. </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Our success depends in large part on our ability
to obtain and maintain protection of our intellectual property, particularly patents, in the United States and other countries
with respect to our product candidates and technology. We seek to protect our proprietary position by filing patent applications
in the United States and abroad related to our product candidates or by in-licensing intellectual property. U.S. patents related
to ANAVEX<sup>&#174;</sup>2-73 are directed to ANAVEX&#174;2-73 in its various optical or crystal forms, its therapeutic indications,
and dosage forms comprising certain doses of ANAVEX<sup>&#174;</sup>2-73 combined with another therapeutic agent. We may not be
able to obtain broader scope patent protection for ANAVEX<sup>&#174;</sup>2-73 as a single drug or in other jurisdictions.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 52; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->53<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The patent position of biotechnology and pharmaceutical
companies generally is highly uncertain, involves complex legal, technological and factual questions and has in recent years been
the subject of much litigation. In addition, the laws of foreign countries may not protect our rights to the same extent as the
laws of the United States, or vice versa. Further, we may not be aware of all third-party intellectual property rights potentially
relating to and/or interfering with our product candidates. Publications of discoveries in the scientific literature often lag
behind the actual discoveries, and patent applications in the United States and other jurisdictions are typically not published
until 18 months after filing or, in some cases, not at all. Therefore, we cannot know with certainty whether we were the first
to make the inventions claimed in our patents or pending patent applications, or that we were the first to file for patent protection
of such inventions. As a result, the issuance, scope, validity, enforceability and/or commercial value of our patent rights are
highly uncertain. Our pending and future patent applications may not result in patents being issued that protect our product candidates,
in whole or in part, or which could effectively prevent others from commercializing competitive product candidates. Even if our
patent applications issue as patents, they may not issue in a form that will provide us with any meaningful protection, prevent
competitors from competing with us or otherwise provide us with any competitive advantage. Our competitors may be able to circumvent
our patents by developing similar or alternative product candidates in a non-infringing manner.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Moreover, we may be subject to a third-party
pre-issuance submission of prior art to the United States Patent and Trademark Office, or the USPTO, or become involved in opposition,
derivation, reexamination, inter partes review, post-grant review or interference proceedings challenging our patent rights or
the patent rights of others. An adverse determination in any such submission, proceeding or litigation could reduce the scope of,
or invalidate, our patent rights, allow third parties to commercialize our product candidates and compete directly with us, without
payment to us, or result in our inability to manufacture or commercialize drugs without infringing on third-party patent rights.
In addition, if the breadth or strength of protection provided by our patents and patent applications is threatened, regardless
of the outcome, it could dissuade companies from collaborating with us to license, develop or commercialize current or future product
candidates.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In addition, the issuance of a patent is not
conclusive as to its inventorship, scope, validity and/or enforceability, and our patents may be challenged in the courts or patent
offices in the United States and abroad. Such challenges may result in loss of exclusivity or freedom to operate or in patent claims
being narrowed, invalidated or held unenforceable, in whole or in part, which could limit our ability to stop others from using
or commercializing similar or identical product candidates, or limit the duration of the patent protection of our product candidates.
Given the amount of time required for the development, testing and regulatory review of new product candidates, patents protecting
such candidates might expire before or shortly after such candidates are commercialized. As a result, our patent portfolio may
not provide us with sufficient rights to exclude others from commercializing drugs similar or identical to ours.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We hold ownership or exclusive rights to twenty-two
U.S. patents, twenty-three U.S. patent applications, and various PCT or ex-U.S. patent applications relating to our drug candidates,
methods associated therewith, and to our research programs. Neither patents nor patent applications ensure the protection of our
intellectual property for a number of reasons, including the following:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<tr>
    <td style="width: 5%; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; width: 5%; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">1.</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">Competitors may
    interfere with our patenting process in a variety of ways. Competitors may claim that Anavex is not entitled to an issued
    patent for a variety of legal reasons. Competitors may also claim that we are infringing their patents and restrict our freedom
    to operate. If a court or, in some circumstances, a board of a national patent authority, agrees, we would lose some or all
    of our patent protection. As a company, we have no meaningful experience with competitors interfering with our patents or
    patent applications.</span></td></tr>
<tr>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">2.</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">Because of the time,
    money and effort involved in obtaining and enforcing patents, our management may spend less time and resources on developing
    potential drug compounds than they otherwise would, which could increase our operating expenses and delay product programs.</span></td></tr>
<tr>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">3.</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">Issuance of a patent
    may not provide significant practical protection. If we receive a patent of narrow scope, then it may be possible for competitors
    to design products that do not infringe our patent(s).</span></td></tr>
<tr>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">4.</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">Anavex is seeking
    patent protection for a number of indications, combination products and drug regimens. The lack of patent protection in global
    markets for a specific end product or indication may inhibit our ability to advance our compounds and may make Anavex less
    attractive to potential partners.</span></td></tr>
</table>

<p style="margin: 0">&#160;</p>

<p style="margin: 0"></p>

<!-- Field: Page; Sequence: 53; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->54<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="margin: 0"></p>

<p style="margin: 0">&#160;</p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<tr>
    <td style="text-align: justify; line-height: 115%; width: 5%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%; width: 5%"><span style="font: 10pt Times New Roman, Times, Serif">5.</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">Defending a patent
    lawsuit takes significant time and can be very expensive.</span></td></tr>
<tr>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">6.</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">If a court decides
    that an Anavex compound, its method of manufacture or use, infringes on a competitor&#8217;s patent, we may have to pay substantial
    damages for infringement.</span></td></tr>
<tr>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">7.</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">A court may prohibit
    us from making, selling or licensing the potential drug compound unless the patent holder grants a license. A patent holder
    is not required to grant a license. If a license is available, we may have to pay substantial royalties or grant cross licenses
    to our patents, and the license terms may be unacceptable.</span></td></tr>
<tr>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">8.</span></td>
    <td style="text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">Redesigning our
    potential drug compounds so that they do not infringe on other patents may not be possible or could require substantial funds
    and time.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">It is also unclear whether our trade secrets
are adequately protected. While we use reasonable efforts to protect our trade secrets, our employees or consultants may unintentionally
or willfully disclose our information to competitors. Enforcing a claim that someone illegally obtained and is using our trade
secrets, like patent litigation, is expensive and time consuming, and the outcome is unpredictable. In addition, courts outside
the United States are sometimes less willing to protect trade secrets. Our competitors may independently develop equivalent knowledge,
methods and know-how.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We may also support and collaborate in research
conducted by government organizations, hospitals, universities or other educational institutions. These research partners may be
unable or unwilling to grant us exclusive rights to technology or products derived from these collaborations.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If we do not obtain required intellectual property
licenses or rights, we could encounter delays in our product development efforts while we attempt to design around other patents
or even be prohibited from developing, manufacturing or selling potential drug compounds requiring these rights or licenses. There
is also a risk that legal disputes may arise as to the rights to technology or potential drug compounds developed in collaboration
with other parties, all with attendant risk, distraction, expense, and lack of predictability.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Patent terms may be inadequate to protect
our competitive position on our product candidates for an adequate amount of time.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Patents have a limited lifespan. In the United
States, if all maintenance fees are timely paid, the natural expiration of a patent is generally 20 years from its earliest U.S.
non-provisional filing date. Various extensions may be available, but the life of a patent, and the protection it affords, is limited.
Even if patents covering our product candidates are obtained, once the patent life has expired, we may be open to competition from
competitive products, including generics or biosimilars. Given the amount of time required for the development, testing and regulatory
review of new product candidates, patents protecting such candidates might expire before or shortly after such candidates are commercialized.
As a result, our owned and licensed patent portfolio may not provide us with sufficient rights to exclude others from commercializing
products similar or identical to ours.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Depending upon the timing, duration and specifics
of FDA marketing approval of product candidates that we identify, one of the U.S. patents covering such product candidate or the
use thereof may be eligible for up to five years of patent term extension under the Hatch-Waxman Act. The Hatch-Waxman Act allows
a maximum of one patent to be extended per FDA approved product as compensation for the patent term lost during the FDA regulatory
review process. A patent term extension cannot extend the remaining term of a patent beyond a total of 14 years from the date of
product approval and only those claims covering such approved drug product, a method for using it or a method for manufacturing
it may be extended. Patent term extension also may be available in certain foreign countries upon regulatory approval of our product
candidates. Nevertheless, we may not be granted patent term extension either in the United States</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 54; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->55<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;<br />
or in any foreign country because of, for example, failing to exercise due diligence during the testing phase or regulatory review
process, failing to apply within applicable deadlines, failing to apply prior to expiration of relevant patents or otherwise failing
to satisfy applicable requirements. Moreover, the term of extension, as well as the scope of patent protection during any such
extension, afforded by the governmental authority could be less than what we request. If we are unable to obtain patent term extension
or restoration, or the term of any such extension is less than we request, the period during which we will have the right to exclusively
market our product may be shortened and our competitors may obtain approval of competing products following our patent expiration
sooner, and our revenue could be reduced, possibly materially.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Also, there are detailed rules and requirements
regarding the patents that may be submitted to the FDA for listing in the Approved Drug Products with Therapeutic Equivalence Evaluations,
or the Orange Book. We may be unable to obtain patents covering our product candidates that contain one or more claims that satisfy
the requirements for listing in the Orange Book. Even if we submit a patent for listing in the Orange Book, the FDA may decline
to list the patent, or a manufacturer of generic drugs may challenge the listing. If one of our product candidates is approved
and a patent covering that product candidate is not listed in the Orange Book, a manufacturer of generic drugs would not have to
provide advance notice to us of any abbreviated new drug application filed with the FDA to obtain permission to sell a generic
version of such product candidate.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>If we fail to comply with our obligations
in the agreements under which we license intellectual property rights from third parties or otherwise experience disruptions to
our business relationships with our licensors, we could lose intellectual property rights that are important to our business.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We are party to an exclusive license agreement
with Life Science Research Israel Ltd., with respect to certain in-licensed intellectual property related to our ANAVEX<sup>&#174;</sup>3-71
product candidate, and we may need to obtain additional licenses from others in the future. Our license agreement with Life Science
Research Israel Ltd. imposes, and we expect that future license agreements will impose, various development, diligence, commercialization,
and other obligations on us. In spite of our efforts, our licensors might conclude that we have materially breached our obligations
under such license agreements and might therefore terminate the license agreements, thereby removing or limiting our ability to
develop and commercialize products and technology covered by these license agreements. If these in-licenses are terminated, or
if the underlying patents fail to provide the intended exclusivity, competitors or other third parties would have the freedom to
seek regulatory approval of, and to market, products identical to ours and we may be required to cease our development and commercialization
of ANAVEX<sup>&#174;</sup>3-71<b><i> </i></b>or other product candidates covered by any such future licenses. Any of the foregoing
could have a material adverse effect on our competitive position, business, financial conditions, results of operations, and prospects.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Moreover, disputes may arise regarding intellectual
property subject to a licensing agreement, including:</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&#160;</p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<tr>
    <td style="width: 5%; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; width: 4%; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the
    scope of rights granted under the license agreement and other interpretation-related issues;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<tr>
    <td style="width: 5%; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; width: 4%; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the
    extent to which our product candidates, technology and processes infringe on intellectual property of the licensor that is
    not subject to the licensing agreement;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<tr>
    <td style="width: 5%; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; width: 4%; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the
    sublicensing of patent and other rights under our collaborative development relationships;</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<tr>
    <td style="width: 5%; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; width: 4%; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">our
    diligence obligations under the license agreement and what activities satisfy those diligence obligations; </span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<tr>
    <td style="width: 5%; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; width: 4%; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="vertical-align: top; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">the
    inventorship and ownership of inventions and know-how resulting from the joint creation or use of intellectual property by
    our licensors and us and our partners; and</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<tr>
    <td style="width: 5%; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; width: 4%; text-align: justify; line-height: 115%"><span style="font: 10pt Times New Roman, Times, Serif">&#9679;</span></td>
    <td style="vertical-align: top; text-align: justify; font-family: Times New Roman, Times, Serif"><span style="font: 10pt Times New Roman, Times, Serif">the
    priority of invention of patented technology.</span></td></tr>
</table>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 55; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->56<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In addition, the agreements under which we
currently license intellectual property or technology from third parties are complex, and certain provisions in such agreements
may be susceptible to multiple interpretations. The resolution of any contract interpretation disagreement that may arise could
narrow what we believe to be the scope of our rights to the relevant intellectual property or technology, or increase what we believe
to be our financial or other obligations under the relevant agreement, either of which could have a material adverse effect on
our business, financial condition, results of operations, and prospects. Moreover, if disputes over intellectual property that
we have licensed prevent or impair our ability to maintain our licensing arrangements on commercially acceptable terms, we may
be unable to successfully develop and commercialize the affected product candidates, which could have a material adverse effect
on our business, financial conditions, results of operations, and prospects.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If we do not obtain required intellectual property
licenses or rights, we could encounter delays in our product development efforts while we attempt to design around other patents
or even be prohibited from developing, manufacturing or selling potential drug compounds requiring these rights or licenses. There
is also a risk that legal disputes may arise as to the rights to technology or potential drug compounds developed in collaboration
with other parties, all with attendant risk, distraction, expense, and lack of predictability.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Third-party claims of intellectual property
infringement may prevent or delay our development and commercialization efforts.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Our success will also depend in part on our
ability to commercialize our compounds without infringing the proprietary rights of others. However, our research, development
and commercialization activities may be subject to claims that we infringe or otherwise violate patents or other intellectual property
rights owned or controlled by third parties. We have not conducted extensive freedom of use patent searches and no assurance can
be given that patents do not exist or could be issued which would have an adverse effect on our ability to market our technology
or maintain our competitive position with respect to our technology. Because patent applications can take many years to issue,
there may be currently pending patent applications which may later result in issued patents that our product candidates may infringe.
In addition, third parties may obtain patents in the future and claim that use of our technologies infringes upon these patents.
If our compounds or other subject matter are claimed under other United States patents or other international patents or are otherwise
protected by third party proprietary rights, we may be subject to infringement actions. In such event, we may challenge the validity
of such patents or other proprietary rights, or we may be required to obtain licenses from such companies in order to develop,
manufacture or market our technology. There can be no assurances that we would be successful in a challenge or be able to obtain
such licenses or that such licenses, if available, could be obtained on commercially reasonable terms. Furthermore, the failure
to succeed in a challenge, develop a commercially viable alternative or obtain needed licenses could be materially adverse. Adverse
consequences include delays in marketing some or all of our potential drug compounds based on our drug technology or the inability
to proceed with the development, manufacture or sale of potential drug compounds requiring such licenses. If we defend ourselves
against charges of patent infringement or to protect our proprietary rights against third parties, substantial costs will be incurred
regardless of whether we are successful. Such proceedings are typically protracted with no certainty of success. An adverse outcome
could subject us to significant liabilities to third parties and force us to curtail or cease the research and development of our
technology.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Parties making claims against us may obtain
injunctive or other equitable relief, which could effectively block our ability to further develop and commercialize ANAVEX<sup>&#174;</sup>2-73
or our other product candidates. Defense of these claims, regardless of their merit, would involve substantial litigation expense
and would be a substantial diversion of employee resources from our business. In the event of a successful claim of infringement
against us, we may have to pay substantial damages, including treble damages and attorneys&#8217; fees for willful infringement,
pay royalties, redesign our infringing products or obtain one or more licenses from third parties, which may be impossible or require
substantial time and monetary expenditure. Additionally, parties making claims against us may be able to sustain the costs of complex
patent litigation more effectively than we can because they have substantially greater resources. Furthermore, because of the substantial
amount of discovery required in connection with intellectual property litigation or administrative proceedings, there is a risk
that some of our confidential information could be compromised by disclosure. In addition, any uncertainties resulting from the
initiation and continuation of any litigation could have material adverse effect on our ability to raise additional funds or otherwise
have a material adverse effect on our business, results of operations, financial condition and prospects.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 56; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->57<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>If we are unable to protect the confidentiality
of our trade secrets, the value of our technology could be materially adversely affected and our business would be harmed.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">While we use reasonable efforts to protect
our trade secrets, our employees or consultants may unintentionally or willfully disclose our information to competitors. Enforcing
a claim that someone illegally obtained and is using our trade secrets, like patent litigation, is expensive and time consuming,
and the outcome is unpredictable. In addition, courts outside the United States are sometimes less willing to protect trade secrets.
Our competitors may independently develop equivalent knowledge, methods and know-how.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We seek to protect our confidential proprietary
information, in part, by confidentiality agreements and invention assignment agreements with our employees, consultants, scientific
advisors, contractors and collaborators. These agreements are designed to protect our proprietary information. However, we cannot
be certain that such agreements have been entered into with all relevant parties, and we cannot be certain that our trade secrets
and other confidential proprietary information will not be disclosed or that competitors will not otherwise gain access to our
trade secrets or independently develop substantially equivalent information and techniques. For example, any of these parties may
breach the agreements and disclose our proprietary information, including our trade secrets, and we may not be able to obtain adequate
remedies for such breaches. We also seek to preserve the integrity and confidentiality of our confidential proprietary information
by maintaining physical security of our premises and physical and electronic security of our information technology systems, but
it is possible that these security measures could be breached. If any of our confidential proprietary information were to be lawfully
obtained or independently developed by a competitor, we would have no right to prevent such competitor from using that technology
or information to compete with us, which could harm our competitive position.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>We may be subject to claims that our
employees, consultants or independent contractors have wrongfully used or disclosed confidential information of third parties or
that our employees have wrongfully used or disclosed alleged trade secrets of their former employers.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">As is common in the biotechnology and pharmaceutical
industry, we employ individuals who were previously employed at universities or other biotechnology or pharmaceutical companies,
including our competitors or potential competitors. Although we try to ensure that our employees, consultants and independent contractors
do not use the proprietary information or know-how of others in their work for us, we may be subject to claims that we or our employees,
consultants or independent contractors have inadvertently or otherwise used or disclosed intellectual property, including trade
secrets or other proprietary information, of any of our employee&#8217;s former employer or other third parties. Litigation may
be necessary to defend against these claims. If we fail in defending any such claims, in addition to paying monetary damages, we
may lose valuable intellectual property rights or personnel, which could adversely impact our business. Even if we are successful
in defending against such claims, litigation could result in substantial costs and be a distraction to management and other employees.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>We may become involved in lawsuits to
protect or enforce our patents or other intellectual property, which could be expensive, time consuming and unsuccessful and could
harm our business.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Competitors may infringe our patents or other
intellectual property. Although we are not currently involved in any litigation, if we were to initiate legal proceedings against
a third party to enforce a patent covering ANAVEX<sup>&#174;</sup>2-73 or our other product candidates, the defendant could counterclaim
that the patent covering our product candidate is invalid and/or unenforceable. In patent litigation in the United States, defendant
counterclaims alleging invalidity and/or unenforceability are commonplace. Grounds for a validity challenge could be an alleged
failure to meet any of several statutory requirements, including lack of novelty, obviousness, written description or non-enablement.
Grounds for an unenforceability assertion could be an allegation that someone connected with prosecution of the patent withheld
relevant information from the USPTO, or made a misleading statement, during prosecution. The outcome following legal assertions
of invalidity and unenforceability is unpredictable.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 57; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->58<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Interference or derivation proceedings provoked
by third parties or brought by us or declared by the USPTO may be necessary to determine the priority of inventions with respect
to our patents or patent applications. An unfavorable outcome could require us to cease using the related technology or to attempt
to license rights to it from the prevailing party. Our business could be harmed if the prevailing party does not offer us a license
on commercially reasonable terms or at all, or if a non-exclusive license is offered and our competitors gain access to the same
technology. Our defense of litigation or interference or derivation proceedings may fail and, even if successful, may result in
substantial costs and distract our management and other employees. In addition, the uncertainties associated with litigation could
have a material adverse effect on our ability to raise the funds necessary to continue our clinical trials, continue our research
programs, license necessary technology from third parties, or enter into development partnerships that would help us bring ANAVEX<sup>&#174;</sup>2-73
or our other product candidates to market.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>We may be subject to claims challenging
the inventorship of our patents and other intellectual property.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We or our licensors may be subject to claims
that former employees, collaborators or other third parties have an interest in our owned or in-licensed patents, trade secrets,
or other intellectual property as an inventor or co-inventor. For example, we or our licensors may have inventorship disputes arise
from conflicting obligations of employees, consultants or others who are involved in developing our product candidates. Litigation
may be necessary to defend against these and other claims challenging inventorship or our or our licensors&#8217; ownership of
our owned or in-licensed patents, trade secrets or other intellectual property. If we or our licensors fail in defending any such
claims, in addition to paying monetary damages, we may lose valuable intellectual property rights, such as exclusive ownership
of, or right to use, intellectual property that is important to our product candidates. Even if we are successful in defending
against such claims, litigation could result in substantial costs and be a distraction to management and other employees. Any of
the foregoing could have a material adverse effect on our business, financial condition, results of operations and prospects.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Obtaining and maintaining our patent
protection depends on compliance with various procedural, document submission, fee payment and other requirements imposed by governmental
patent agencies, and our patent protection could be reduced or eliminated for non-compliance with these requirements.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Periodic maintenance fees, renewal fees, annuity
fees and various other governmental fees on patents and/or applications will be due to be paid to the USPTO and various governmental
patent agencies outside of the United States in several stages over the lifetime of the patents and/or applications. We have systems
in place to remind us to pay these fees, and we employ an outside firm and rely on our outside counsel to pay these fees due to
non-U.S. patent agencies. The USPTO and various non-U.S. governmental patent agencies require compliance with a number of procedural,
documentary, fee payment and other similar provisions during the patent application process. We employ reputable law firms and
other professionals to help us comply, and in many cases, an inadvertent lapse can be cured by payment of a late fee or by other
means in accordance with the applicable rules. However, there are situations in which non-compliance can result in abandonment
or lapse of the patent or patent application, resulting in partial or complete loss of patent rights in the relevant jurisdiction.
In such an event, our competitors might be able to enter the market and this circumstance would have a material adverse effect
on our business.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>We may not be able to protect our intellectual
property rights throughout the world.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Filing, prosecuting and defending patents on
our product candidates in all countries throughout the world would be prohibitively expensive, and our intellectual property rights
in some countries outside the United States can be less extensive than those in the United States. In addition, the laws of some
foreign countries do not protect intellectual property rights to the same extent as federal and state laws in the United States.
Consequently, we may not be able to prevent third parties from practicing our inventions in all countries outside the United States,
or from selling or importing products made using our inventions in and into the United States or other jurisdictions. Competitors
may use our technologies in jurisdictions where we have not obtained patent protection to develop their own products and may also
export infringing products to territories where we have patent protection, but enforcement is not as strong as that in the United
States. These products may compete with our products and our patents or other intellectual property rights may not be effective
or sufficient to prevent them from competing.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 58; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->59<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Changes in patent law could diminish
the value of our patents and patent applications in general, thereby impairing our ability to protect our product candidates.</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Changes in either the patent laws or interpretation
of the patent laws in the United States and other countries could increase the uncertainties and costs surrounding the prosecution
of patent applications and the enforcement or defense of issued patents. After March 2013, under the Leahy-Smith America Invents
Act, or the America Invents Act, enacted in September 2011, the United States transitioned to a first inventor to file system in
which, assuming that other requirements for patentability are met, the first inventor to file a patent application will be entitled
to the patent on an invention regardless of whether a third party was the first to invent the claimed invention. A third party
that files a patent application in the USPTO after March 2013, but before us could therefore be awarded a patent covering an invention
of ours even if we had made the invention before it was made by such third party. This will require us to be cognizant of the time
from invention to filing of a patent application. Since patent applications in the United States and most other countries are confidential
for a period of time after filing or until issuance, we cannot be certain that we or our licensors were the first to either (i)
file any patent application related to our product candidates or (ii) invent any of the inventions claimed in our or our licensor&#8217;s
patents or patent applications. The America Invents Act also includes a number of significant changes that affect the way patent
applications will be prosecuted and also may affect patent litigation. Therefore, the America Invents Act and its implementation
could increase the uncertainties and costs surrounding the prosecution of our owned or in-licensed patent applications and the
enforcement or defense of our owned or in-licensed issued patents, all of which could have a material adverse effect on our business,
financial condition, results of operations, and prospects.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In addition, the patent positions of companies
in the development and commercialization of pharmaceuticals are particularly uncertain. Recent U.S. Supreme Court rulings have
narrowed the scope of patent protection available in certain circumstances and weakened the rights of patent owners in certain
situations. This combination of events has created uncertainty with respect to the validity and enforceability of patents, once
obtained. Depending on future actions by the U.S. Congress, the federal courts, and the USPTO, the laws and regulations governing
patents could change in unpredictable ways that could have a material adverse effect on our existing patent portfolio and our ability
to protect and enforce our intellectual property in the future.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The risk factors disclosed in this Annual Report
on Form 10-K could materially and adversely affect our business, financial condition and results of operations. The risks described
herein are not the only risks we face. Our operations could also be affected by additional factors that are not presently known
to us or by factors that we currently consider immaterial to our business.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_004"></span>ITEM 1B. UNRESOLVED
STAFF COMMENTS </span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">None.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_005"></span>ITEM 2. PROPERTIES</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We do not own any real property. We maintain
a corporate head office at 630 5th Avenue, 20th Floor, New York, NY, USA. Our lease costs for this office are approximately $10,000
per month. We believe our offices are suitable and adequate to operate our business currently, as they provide us with sufficient
space to conduct our operations.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_006"></span>ITEM 3. LEGAL
PROCEEDINGS</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">We know of no material
pending legal proceedings, other than ordinary routine litigation incidental to our business, to which our Company or our subsidiary
is a party or of which any of their property is subject. There are no proceedings in which any of our directors, officers or affiliates,
or any registered or beneficial stockholder holding more than 5% of our shares, is an adverse party or has a material interest
adverse to our or our subsidiary&#8217;s interest.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"></p>

<!-- Field: Page; Sequence: 59; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->60<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;&#160;</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_007"></span>ITEM 4. MINE
SAFETY DISCLOSURES</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">Not applicable.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span id="a_008"></span>PART II</p>

<p style="font: bold 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-style: normal"><span id="a_009"></span>ITEM 5. MARKET
FOR REGISTRANT&#8217;S COMMON EQUITY, RELATED STOCKHOLDER MATTERS AND ISSUER PURCHASES OF EQUITY SECURITIES</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Market information</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Our common stock is quoted on the Nasdaq Global
Select Stock Market (&#8220;Nasdaq&#8221;) under the symbol &#8220;AVXL.&#8221;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Holders of Common Stock </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">As of <span style="color: black">November 24,
2023</span>, there were approximately 48 stockholders of record, and 82,086,511 shares of our common stock were issued and outstanding.
Most of our stockholders hold their shares in street name.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Dividends </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We have not paid any cash dividends on our
common stock and have no intention of paying any dividends on the shares of our common stock. Our current policy is to retain earnings,
if any, for use in our operations and in the development of our business. Our future dividend policy will be determined from time
to time by our Board of Directors.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Recent Sales of Unregistered Securities
</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Since the beginning of our fiscal year ended
September 30, 2023, we have not sold any equity securities that were not registered under the Securities Act of 1933 that were
not previously reported in a quarterly report on Form 10-Q or in a current report on Form 8-K.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Repurchases of Equity Securities by Our
Company and Affiliated Purchasers</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">None.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><b>ITEM 6 [Reserved]</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><b><i>&#160;</i></b></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-style: normal"><span id="a_010"></span>ITEM 7 MANAGEMENT&#8217;S
DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATION </span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The following discussion should be read
in conjunction with our consolidated financial statements and related notes thereto included elsewhere in this report. Past operating
results are not necessarily indicative of results that may occur in future periods. This discussion contains forward-looking statements,
which involve a number of risks and uncertainties. See <b><i>Forward Looking Statements</i></b> included elsewhere in this report.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 60; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->61<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Financial Operations Overview</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: italic 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-style: normal">We
are in the development stage and have not earned any revenues since our inception in 2004. We do not anticipate earning any revenues
until we can establish an alliance with other companies to develop, co-develop, license, acquire or market our products.</span></p>

<p style="font: italic 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify"><span style="font-family: Times New Roman, Times, Serif">Our
operating costs consist primarily of research and development activities including the cost of clinical studies and clinical supplies
as well as clinical drug manufacturing and formulation. Research and development expenses also include personnel related costs such as
salaries and wages, and third-party contract research organization (CRO) expenses in support of these clinical studies. Personnel costs
include salaries and wages, benefits, and non-cash stock-based compensation charges associated with options and other equity awards granted
to employees and consultants who are directly engaged in support of our research and development activities.</span></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">General and administrative expenses
consist of personnel costs, expenses for outside professional services and expenses associated with operating as a public company.
Personnel costs consist of salaries and wages, benefits and stock-based compensation for general and administrative personnel.
Outside professional services and public company expenses, include expenses related to compliance and reporting, additional insurance
expenses, audit and SOX compliance, expenses associated with patent research, applications and filings, investor and stockholder
relations activities and other administrative expenses and professional services.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt"><b>Comparison of year ended September 30, 2023 to year
ended September 30, 2022</b></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt"><b><i>Operating Expenses</i></b></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt"><b><i></i></b></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt">Our operating expenses for fiscal 2023 increased to
$55.8 million, from $51.0 million in fiscal 2022. The increase is attributable to an increase in research and development expenses
of $5.7 million in 2023 to $43.7 million.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">The following table summarizes our research and development
expenses for the years ended September 30, 2023, and 2022 (in thousands):</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
    <td style="text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2023</b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2022</b></span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="width: 56%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Costs of external service
    providers</span></td><td style="width: 8%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td><td style="width: 12%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">22,542</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 8%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td><td style="width: 12%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">18,102</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Personnel costs</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">10,264</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">8,012</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Stock-based compensation</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">10,812</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">11,250</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">License fees</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">500</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Other common costs</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">99</span></td><td style="padding-bottom: 1pt; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">52</span></td><td style="padding-bottom: 1pt; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Total research
    and development costs</span></td><td style="padding-bottom: 2.5pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td><td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">43,717</span></td><td style="padding-bottom: 2.5pt; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 2.5pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td><td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">37,91</span><span style="font-family: Times New Roman, Times, Serif">6</span></td><td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif">&#160;</span></td></tr>
</table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">External service providers cost by product
candidate was as follows (in thousands):</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
    <td style="text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2023</b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2022</b></span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="width: 56%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">ANAVEX<sup>&#174;</sup>2-73</span></td><td style="width: 8%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td><td style="width: 12%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">19,540</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 8%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td><td style="width: 12%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">15,510</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">ANAVEX<sup>&#174;</sup>3-71</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">2,624</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">2,251</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">All other product candidates</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">6</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">298</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Other external service
    provider costs</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">372</span></td><td style="padding-bottom: 1pt; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">43</span></td><td style="padding-bottom: 1pt; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Total external
    service provider costs</span></td><td style="padding-bottom: 2.5pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td><td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">22,542</span></td><td style="padding-bottom: 2.5pt; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 2.5pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td><td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">18,10</span><span style="font-family: Times New Roman, Times, Serif">2</span></td><td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif">&#160;</span></td></tr>
</table>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify"><span style="font-family: Times New Roman, Times, Serif">The
increase in external service provider costs from fiscal 2022 to fiscal 2023 is primarily due to (1) an increase in manufacturing
costs for both ANAVEX<sup>&#174;</sup>2-73 and ANAVEX<sup>&#174;</sup>3-71, in preparation for planned clinical trials or studies
and (2) an increase in clinical trial expenditures related to our Rett program in connection with the completed enrollment and
dosing of our Phase 2/3 Excellence pediatric clinical trial.</span></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif">During
fiscal 2023, our personnel costs increased to $10.3 million from $8.0 million as a result of our expanded team.</span> <span style="font-family: Times New Roman, Times, Serif">However,
this was offset by a decrease in stock-based compensation expense as a result of the vesting of previously awarded milestone-based
option awards.</span></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif">&#160;</span></p>

<!-- Field: Page; Sequence: 61; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->62<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">General and administrative expenses
for fiscal 2023 decreased to $12.0 million, from $13.1 million in fiscal 2022, most significantly related to a decrease in non-cash
stock option compensation charges as a result of the vesting of previously awarded milestone-based option awards.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify"><span style="font-family: Times New Roman, Times, Serif">During
fiscal 2023, we utilized cash and cash equivalents of $27.8 million to fund our operations, compared to $24.2 million during fiscal
2022. Our cash position increased slightly to $151.0 million at September 30, 2023, an increase of $1.9 million over the prior
year.</span> <span style="font-family: Times New Roman, Times, Serif">Cash for operations was generated through the issuance of
shares of common stock under the financing arrangements described below.</span></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify"><span style="font-family: Times New Roman, Times, Serif">We
expect to continue to see an increase in our research and development expenditures as we advance our ANAVEX<sup>&#174;</sup>2-73
clinical studies, including planned advancement of ANAVEX<sup>&#174;</sup>2-73 for Parkinson</span>&#8217;<span style="font-family: Times New Roman, Times, Serif">s
disease program, ongoing extension studies of our current clinical programs, continued advancement of our other pipeline compounds
such as ANAVEX<sup>&#174;</sup>3-71, and as we continue to add additional staffing to manage and support these clinical initiatives.
</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Other income (net)</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">Net other income for the year ended
September 30, 2023 was $8.3 million as compared to $3.4 million for fiscal 2022. The primary reason for the increase in other
income was due to an increase in interest income earned on cash and cash equivalents, due to an increase in market wide interest
rates year over year.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">During fiscal 2023, we recorded
$2.7 million in research and development incentive income, consisting of the Australian research and development incentive credit
administered through the Australian Tax Office, in connection with fiscal 2023 eligible expenditures. In comparison, research
and development incentive income for fiscal 2022 was $3.3 million in connection with fiscal 2022 eligible expenditures. We expect
to continue to receive support from the Australian government for various clinical trials being conducted within Australia.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt"><b><i>Net loss</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Net loss for fiscal 2023 was $47.5 million,
or $0.60 per share, compared to a net loss of approximately $48.0 million, or $0.62 per share for fiscal 2022.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>Liquidity and Capital Resources </b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Working Capital (in thousands)</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
<td style="text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-weight: bold; padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2023</b></span></td>
<td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2022</b></span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="width: 56%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Current Assets</span></td>
<td style="width: 8%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td>
<td style="width: 12%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">154,386</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 8%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td>
<td style="width: 12%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">152,705</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="text-align: left; padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">Current Liabilities</span></td>
<td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">12,534</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">10,214</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="text-align: left; padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">Working Capital</span></td>
<td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">141,852</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">142,491</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
</table>


<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">At September 30, 2023, we had <span style="color: black">$151.0
million</span> in cash and cash equivalents, an increase from $149.2 million at September 30, 2022.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify"><span style="color: black">We intend
to continue to use our capital resources to advance our clinical trials for ANAVEX<sup>&#174;</sup>2-73 and ANAVEX<sup>&#174;</sup>3-71,
and to perform work necessary to prepare for future development of our pipeline compounds</span>.</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>Cash Flows </i></p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><i>&#160;</i></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-weight: normal">Following
is a summary of sources of cash flows for the years ended September 30, 2023 and 2022 (in thousands)</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
<td style="text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td colspan="3" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2023</b></span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
<td colspan="3" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2022</b></span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="width: 56%; font-family: Times New Roman, Times, Serif; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Cash flows used in operating activities</span></td>
<td style="width: 8%; font-family: Times New Roman, Times, Serif"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 1%; font-family: Times New Roman, Times, Serif; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td>
<td style="width: 12%; font-family: Times New Roman, Times, Serif; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">(27,785</span></td>
<td style="width: 1%; font-family: Times New Roman, Times, Serif; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">)</span></td>
<td style="width: 8%; font-family: Times New Roman, Times, Serif"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 1%; font-family: Times New Roman, Times, Serif; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td>
<td style="width: 12%; font-family: Times New Roman, Times, Serif; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">(24,238</span></td>
<td style="width: 1%; font-family: Times New Roman, Times, Serif; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">)</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="font-family: Times New Roman, Times, Serif; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Cash flows provided by financing activities</span></td>
<td style="font-family: Times New Roman, Times, Serif"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">29,651</span></td>
<td style="font-family: Times New Roman, Times, Serif; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">21,288</span></td>
<td style="font-family: Times New Roman, Times, Serif; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font-family: Times New Roman, Times, Serif; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Increase (decrease) in cash</span></td>
<td style="font-family: Times New Roman, Times, Serif"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td>
<td style="font-family: Times New Roman, Times, Serif; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">1,866</span></td>
<td style="font-family: Times New Roman, Times, Serif; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td>
<td style="font-family: Times New Roman, Times, Serif; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">(2,950</span></td>
<td style="font-family: Times New Roman, Times, Serif; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">)</span></td></tr>
</table>


<p style="font: italic 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: italic 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 62; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->63<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: italic 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: italic 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: italic 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Cash flow used in operating activities</p>

<p style="font: italic 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">There was an increase in cash used in operating activities
of $1.9 million during fiscal 2023 primarily due to the collection of incentive and tax receivables in the comparable period.</p>

<p style="font: italic 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Cash flow provided by financing activities</p>

<p style="font: italic 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">Cash provided by financing activities <span style="color: black">in
fiscal 2023 </span>was $29.7 million, primarily attributable to cash received from the issuance of common shares at various market
prices under the 2023 Purchase Agreement (as defined below).</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">Cash provided by financing activities
<span style="color: black">in fiscal 2022 </span>was $21.3 million, net of financing costs, primarily attributable to cash received
from the issuance of common shares at various market prices under the Sales Agreement.</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Other Financings</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>2023 Purchase Agreement</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">On February 3, 2023, the Company entered into
a $150,000,000 purchase agreement (the &#8220;2023 Purchase Agreement&#8221;) with Lincoln Park Capital Fund, LLC (&#8220;Lincoln
Park&#8221;), pursuant to which the Company has the right to sell and issue to Lincoln Park, and Lincoln Park is obligated to purchase,
up to $150.0 million in value of its shares of Common Stock from time to time over a three-year period until February 3, 2026.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">On any business day and subject to certain
customary conditions, the Company may direct Lincoln Park to purchase up to 200,000 shares of Common Stock (such purchases, &#8220;<span style="text-decoration: underline">Regular
Purchases</span>&#8221;). The amount of a Regular Purchase may increase under certain circumstances based on the market price of the
Common Stock; provided, however, that Lincoln Park&#8217;s committed obligation under any Regular Purchase shall not exceed $4.0
million. The purchase price of shares of Common Stock will be based on the then prevailing market prices of such shares at the
time of sales as described in the Purchase Agreement. There are no limits on the price per share that Lincoln Park may pay to purchase
Common Stock under the Purchase Agreement. In addition, if the Company has directed Lincoln Park to purchase the full amount of
Common Stock available as a Regular Purchase on a given day, it may direct Lincoln Park to purchase additional amounts as &#8220;accelerated
purchases&#8221; and &#8220;additional accelerated purchases,&#8221; each as set forth in the Purchase Agreement.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Purchase Agreement limits the Company&#8217;s
sale of shares of Common Stock to Lincoln Park to 15,606,426 shares of Common Stock, representing 19.99% of the shares of the Common
Stock outstanding on the date of the Purchase Agreement unless (i)&#160;stockholder approval is obtained to issue more than such
amount or (ii)&#160;the average price of all applicable sales of Common Stock to Lincoln Park under the Purchase Agreement equals
or exceeds the lower of (A) the closing price of the Common Stock on the Nasdaq Capital Market immediately preceding the Execution
Date or (B) the average of the closing price of the Common Stock on the Nasdaq Capital Market for the five Business Days immediately
preceding the Execution Date.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Purchase Agreement also prohibits the Company
from directing Lincoln Park to purchase any shares of Common Stock if those shares, when aggregated with all other shares of Common
Stock then beneficially owned by Lincoln Park and its affiliates, would result in Lincoln Park and its affiliates having beneficial
ownership, at any single point in time, of more than 4.99% of the then total outstanding shares of Common Stock, as calculated
pursuant to Section&#160;13(d) of the Securities Exchange Act of 1934, as amended, and Rule 13d-3 thereunder.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In consideration for entering into the 2023
Purchase Agreement, the Company issued to Lincoln Park 75,000 shares of Common Stock as a commitment fee (the &#8220;initial commitment
shares&#8221;) during the year ended September 30, 2023 and agreed to issue up to 75,000 shares pro rata (collectively with the
initial commitment shares, the &#8220;commitment shares&#8221;), when and if, Lincoln Park purchased, at the Company&#8217;s discretion,
the $150.0 million aggregate commitment.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 63; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->64<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">During the year ended September 30, 2023, the
Company issued to Lincoln Park an aggregate of 3,288,943 (2022: 0) shares of Common Stock under the 2023 Purchase Agreement, including
3,275,000 (2022: 0) shares of Common Stock for aggregate proceeds of $27.9 million (2022: $0) and 88,943 (2022: 0) commitment shares
(inclusive of the 75,000 initial commitment shares).</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">As of&#160;September 30, 2023, an amount of
$122.1 million in shares of our common stock remain available for purchase by Lincoln Park under the 2023 Purchase Agreement.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>Controlled Equity Offering Sales
Agreement</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">On May 1, 2020, we entered into an Amended
and Restated Sales Agreement (the &#8220;Sales Agreement&#8221;) with Cantor Fitzgerald &amp; Co. and SVB Leerink LLC (the &#8220;Sales
Agents&#8221;), pursuant to which we may offer and sell shares of common stock registered under an effective registration statement
from time to time through the Sales Agents (the &#8220;At-the-Market Offering&#8221;).</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Upon delivery of a placement notice based on
our instructions and subject to the terms and conditions of the Sales Agreement, the Sales Agents may sell shares of common stock
by methods deemed to be an &#8220;at the market offering&#8221;, in negotiated transactions at market prices prevailing at the
time of sale or at prices related to such prevailing market prices, or by any other method permitted by law, including negotiated
transactions, subject to our prior written consent. We are not obligated to make any sales of shares under the Sales Agreement.
We or the Sales Agents may suspend or terminate the At-the-Market Offering upon notice to the other party, subject to certain conditions.
The Sales Agents will act as agents on a commercially reasonable efforts basis consistent with their normal trading and sales practices,
applicable state and federal law, and rules and regulations and the rules of Nasdaq.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We have agreed to pay the Sales Agents&#8217;
commissions for their services of 3.0% of the gross proceeds from the sale of shares of Common Stock pursuant to the Sales Agreement.
We have also agreed to provide the Sales Agents with customary indemnification and contribution rights.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">No shares were sold during the year ended September
30, 2023 under the Sales Agreement. The Company currently does not have access to sell shares of common stock with the Sales Agents.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">During the year ended September 30, 2022, 1,623,813
shares were sold under the Sales Agreement for gross proceeds of $21.0 million (net proceeds of $20.3 million after deducting commissions
and offering expenses).</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt"><b>2019 Purchase Agreement</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">On June 7, 2019, we
entered into a Purchase Agreement (the &#8220;2019 Purchase Agreement&#8221;) with Lincoln Park, as amended on July 1, 2020, pursuant
to which Lincoln Park committed to purchase up to $50.0 million of our common stock. Concurrently with the execution of the 2019
Purchase Agreement in 2019, we issued 324,383 shares of our common stock to Lincoln Park as a fee for its commitment to purchase
shares of our common stock under the 2019 Purchase Agreement and became obligated to issue up to 162,191 shares pro rata, when
and if Lincoln Park purchased, at our discretion, the $50.0 million aggregate commitment.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">During fiscal year 2021, the Company
issued to Lincoln Park an aggregate of 4,086,209 shares of common stock under the 2019 Purchase Agreement, including 4,007,996
shares of common stock for an aggregate purchase price of $24.1 million and 78,213 commitment shares. As of<span style="color: black">
September 30, 2023 and 2022, no shares of our common stock remained available for purchase by Lincoln Park under the 2019 Purchase
Agreement.</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 64; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->65<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Off-Balance Sheet Arrangements</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">We have no off-balance sheet arrangements
that have or are reasonably likely to have a current or future effect on our financial condition, changes in financial condition,
revenues or expenses, results of operations, liquidity, capital expenditures or capital resources that are material to our stockholders.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="text-transform: uppercase"><b>Application
of Critical Accounting Policies</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="text-transform: uppercase"><b>&#160;</b></span></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify"><span style="font-family: Times New Roman, Times, Serif">Our
financial statements and accompanying notes are prepared in accordance with generally accepted accounting principles in the United
States. Preparing financial statements requires management to make estimates and assumptions that affect the reported amounts
of assets, liabilities, revenue and expenses. These estimates and assumptions are affected by management</span>&#8217;<span style="font-family: Times New Roman, Times, Serif">s
application of accounting policies. We believe that understanding the basis and nature of the estimates and assumptions involved
with the following aspects of our financial statements is critical to an understanding of our financial statements.</span></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">We base our assumptions and estimates
on historical experience and other sources that we believe to be reasonable at the time. Actual results may vary from our estimates
due to changes in circumstances, politics, global economics, general business conditions and other factors. Our significant estimates
are related to the valuation of warrants and options.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">There are accounting policies that
we believe are significant to the presentation of our financial statements. The most significant of these accounting policies
relates to the accounting for our research and development expenses and stock-based compensation expense.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt"><i>Research and Development Expenses</i></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt"><i></i></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify"><span style="font-family: Times New Roman, Times, Serif">Research
and development costs are expensed as incurred. These expenses are comprised of the costs of the Company</span>&#8217;<span style="font-family: Times New Roman, Times, Serif">s
proprietary research and development efforts, including preclinical studies, clinical trials, manufacturing costs, employee salaries
and benefits and stock-based compensation expense, contract services including external research and development expenses incurred
under arrangements with third parties such as contract research organizations (</span>&#8220;<span style="font-family: Times New Roman, Times, Serif">CROs</span>&#8221;<span style="font-family: Times New Roman, Times, Serif">),
facilities costs, overhead costs and other related expenses. Milestone payments made by the Company to third parties are expensed
when the specific milestone has been achieved. Manufacturing costs are expensed as incurred in accordance with Accounting Standard
Codification (</span>&#8220;<span style="font-family: Times New Roman, Times, Serif">ASC</span>&#8221;<span style="font-family: Times New Roman, Times, Serif">)
730, Research and Development, as these materials have no alternative future use outside of their intended use.</span></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">Nonrefundable advance payments
for goods or services that will be used or rendered for future research and development activities are deferred and amortized
over the period that the goods are delivered, or the related services are performed, subject to an assessment of recoverability.
The Company makes estimates of costs incurred in relation to external CROs, and clinical site costs. The Company analyzes the
progress of clinical trials, including levels of patient enrollment, invoices received and contracted costs when evaluating the
adequacy of the amount expensed and the related prepaid asset and accrued liability. Significant judgments and estimates must
be made and used in determining the accrued balance and expense in any accounting period. The Company reviews and accrues CRO
expenses and clinical trial study expenses based on work performed and relies upon estimates of those costs applicable to the
stage of completion of a study. Accrued CRO costs are subject to revisions as such trials progress to completion. Revisions are
charged to expense in the period in which the facts that give rise to the revision become known. With respect to clinical site
costs, the financial terms of these agreements are subject to negotiation and vary from contract to contract. Payments under these
contracts may be uneven and depend on factors such as the achievement of certain events, the successful recruitment of patients,
the completion of portions of the clinical trial or similar conditions. The objective of our policy is to record expenses in our
financial statements based on actual services received and efforts expended. As such, expense accruals related to clinical site
costs are recognized based on our estimate of the degree of completion of the event or events specified in the specific clinical
trial contract.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0; text-align: justify">In addition, we incur expenses
in respect of the acquisition of intellectual property relating to patents and trademarks. The probability of success and length
of time to develop commercial applications of the drugs subject to the acquired patents and trademarks is difficult to determine
and numerous risks and uncertainties exist with respect to the timely completion of the development projects. There is no assurance
the acquired patents and trademarks will ever be successfully commercialized. Due to these risks and uncertainties, we expense
the acquisition of patents and trademarks</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<!-- Field: Page; Sequence: 65; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->66<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt"><i>Stock-based Compensation</i></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt">We account for all stock-based payments and awards under
the fair value-based method.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">The fair value of all share purchase
options and warrants are expensed over their contractual vesting period, or over the expected performance period for only the
portion of awards expected to vest, in the case of milestone-based vesting, with a corresponding increase to additional paid-in
capital.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">Compensation costs for stock-based
payments with graded vesting are recognized on a straight-line basis. Stock-based compensation expense is adjusted for actual
forfeitures of unvested awards as they occur.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">We have granted share purchase
option awards that vest upon achievement of certain performance criteria, or milestone-based awards. We estimate an implicit service
period for achieving performance criteria for each award and recognizes the resulting fair value as expense over the implicit
service period when we conclude that achieving the performance criteria is probable. We periodically review and update as appropriate
our estimates of implicit service periods and conclusions on achieving the performance criteria. Performance awards vest upon
achievement of the performance criteria.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify"><span style="font-family: Times New Roman, Times, Serif">We
use the Black-Scholes option valuation model to calculate the fair value of share purchase options and warrants at the date of
the grant. This model requires the input of subjective assumptions, including the expected price volatility, and expected life
of each&#160;award. These assumptions consist of estimates of future market conditions, which are inherently uncertain, and therefore,
are subject to management</span>&#8217;<span style="font-family: Times New Roman, Times, Serif">s judgment. Changes in these assumptions
can materially affect the fair value estimates.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 21.6pt; text-indent: -21.6pt"><b>RECENT ACCOUNTING PRONOUNCEMENTS</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 21.6pt; text-indent: -21.6pt"><b><i>&#160;</i></b></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">For a discussion of recent accounting
pronouncements and their possible effect on our results, see Note 2 to our Consolidated Financial Statements found elsewhere in
this Annual Report.</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_011"></span>ITEM 7A QUANTITATIVE
AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK </span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>Interest Rate Risk</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif">We
invest our excess cash in investment-grade, interest-bearing securities.</span> <span style="font-family: Times New Roman, Times, Serif">The
primary objective of our investment policy is to preserve principal and liquidity. To achieve this objective, our investment policy
allows for investments in domestic money market certificates, certificates of deposit, money market funds, bonds or commercial
papers, and establishes diversification and credit quality requirements and limits investments by maturity and issuer.</span>
<span style="font-family: Times New Roman, Times, Serif">At September 30, 2023 and 2022, the majority of our excess cash was held
in a JP Morgan Chase Prime Money Market Fund.</span> <span style="font-family: Times New Roman, Times, Serif">The average amount
invested at any given time throughout the year ended September 30, 2023 was $138.4 million (high: $145.4 million; low: $129.5
million) and the average rate of return was 4.69%.</span> <span style="font-family: Times New Roman, Times, Serif">A hypothetical
100 basis point change in interest rates during any of the periods presented would not have a material impact on the fair market
value of our cash and cash equivalents as of September 30, 2023 and 2022 and would impact our net loss by approximately $1.4 million.
To date, we have not experienced a loss of principal on any of our investments and as of September 30, 2023 we did not have any
allowance for credit losses from our cash and cash equivalents.</span></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif">&#160;</span></p>

<!-- Field: Page; Sequence: 66; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->67<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>Foreign Exchange Risk</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">We face foreign exchange risk as a result of entering
into transactions denominated in currencies other than U.S. dollars and as a result of the existence of sales and tax incentive
receivables denominated in other than U.S. dollars. Due to the uncertain timing of expected payments in foreign currencies, we
do not utilize any forward exchange contracts. All foreign transactions settle on the applicable spot exchange basis at the time
such payments are made. Volatile market conditions and supply chain shortages may result in significant changes in exchange rates,
and in particular a change in foreign currencies values relative to the U.S. dollar may affect our operating expenses as expressed
in U.S. dollars. An adverse movement in foreign exchange rates could have a material effect on payments made to foreign suppliers.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">For the year ended September 30, 2023, a majority of
our expenses were denominated in U.S. dollars. A hypothetical 10% change in foreign exchange rates applied to foreign currency
transactions for the year ended September 30, 2023 would not have had a material impact on our consolidated financial statements.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify"><span style="font-family: Times New Roman, Times, Serif">At
September 30, 2023, we held net assets of $5.0 million (AUD $7.8 million) denominated in Australian dollars.</span> <span style="font-family: Times New Roman, Times, Serif">A
hypothetical 10% change in foreign exchange rates at September 30, 2023 would result in a change in reported net assets of +/-
$0.5 million.</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>Inflation Risk</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Inflation generally may affect us by
increasing our cost of labor and clinical trial costs. We do not believe that inflation has had a material impact on our results
of operations during the periods presented.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 67; Value: 6 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->68<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_012"></span>ITEM 8. FINANCIAL
STATEMENTS AND SUPPLEMENTARY DATA</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"></span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"></span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><b></b></p><p style="margin: 0"></p>



<p style="margin: 0"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>ANAVEX
LIFE SCIENCES CORP.</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">CONSOLIDATED
FINANCIAL STATEMENTS</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30, 2023</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>

<!-- Field: Page; Sequence: 68; Options: NewSection; Value: 1 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->1<!-- Field: /Sequence --></p></div>
    <div style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: Black">&#160;&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><span style="text-transform: uppercase"><b>REPORT
OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="text-transform: uppercase"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="text-transform: uppercase">B</span><span style="background-color: white">oard
of Directors and Shareholders</span><br />
Anavex Life Sciences Corp.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0">Opinion on internal control over financial reporting</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">We have audited the internal control over financial reporting of Anavex
Life Sciences Corp. (a Nevada corporation) and subsidiaries (the &#8220;Company&#8221;) as of September 30, 2023, based on criteria established
in the <i>2013 Internal Control&#8212;Integrated Framework</i> issued by the Committee of Sponsoring Organizations of the Treadway Commission
(&#8220;COSO&#8221;). In our opinion, the Company maintained, in all material respects, effective internal control over financial reporting
as of September 30, 2023, based on criteria established in the 2013 <i>Internal Control&#8212;Integrated Framework </i>issued by COSO.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">We also have audited, in accordance with the standards of the Public Company
Accounting Oversight Board (United States) (&#8220;PCAOB&#8221;), the consolidated financial statements of the Company as of and for the
year ended September 30, 2023, and our report dated November 27, 2023 expressed an unqualified opinion on those financial statements.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0">Basis for opinion</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">The Company&#8217;s management is responsible for maintaining effective
internal control over financial reporting and for its assessment of the effectiveness of internal control over financial reporting, included
in the accompanying Management&#8217;s Annual Report on Internal Control over Financial Reporting. Our responsibility is to express an
opinion on the Company&#8217;s internal control over financial reporting based on our audit. We are a public accounting firm registered
with the PCAOB and are required to be independent with respect to the Company in accordance with the U.S. federal securities laws and
the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">We conducted our audit in accordance with the standards of the PCAOB. Those
standards require that we plan and perform the audit to obtain reasonable assurance about whether effective internal control over financial
reporting was maintained in all material respects. Our audit included obtaining an understanding of internal control over financial reporting,
assessing the risk that a material weakness exists, testing and evaluating the design and operating effectiveness of internal control
based on the assessed risk, and performing such other procedures as we considered necessary in the circumstances. We believe that our
audit provides a reasonable basis for our opinion.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0">Definition and limitations of internal control over financial reporting</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">A company&#8217;s internal control over financial reporting is a process
designed to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements
for external purposes in accordance with generally accepted accounting principles. A company&#8217;s internal control over financial reporting
includes those policies and procedures that (1) pertain to the maintenance of records that, in reasonable detail, accurately and fairly
reflect the transactions and dispositions of the assets of the company; (2) provide reasonable assurance that transactions are recorded
as necessary to permit preparation of financial statements in accordance with generally accepted accounting principles, and that receipts
and expenditures of the company are being made only in accordance with authorizations of management and directors of the company; and
(3) provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use, or disposition of the company&#8217;s
assets that could have a material effect on the financial statements.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">Because of its inherent limitations, internal control over financial reporting
may not prevent or detect misstatements. Also, projections of any evaluation of effectiveness to future periods are subject to the risk
that controls may become inadequate because of changes in conditions, or that the degree of compliance with the policies or procedures
may deteriorate.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">/s/ GRANT THORNTON LLP</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">Melville, New York<br />
November 27, 2023</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"></p>

<!-- Field: Page; Sequence: 69; Value: 1 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->2<!-- Field: /Sequence --></p></div>
    <div style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><span style="text-transform: uppercase"><b>REPORT
OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="text-transform: uppercase"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="background-color: white">Board of Directors and Shareholders</span><br />
Anavex Life Sciences Corp.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0">Opinion on the financial statements</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">We have audited the accompanying consolidated balance sheets of Anavex
Life Sciences Corp. (a Nevada corporation) and subsidiaries (the &#8220;Company&#8221;) as of September 30, 2023 and 2022, the related
consolidated statements of operations and comprehensive loss, changes in stockholders&#8217; equity, and cash flows for each of the two
years in the period ended September 30, 2023, and the related notes (collectively referred to as the &#8220;financial statements&#8221;).
In our opinion, the consolidated financial statements present fairly, in all material respects, the financial position of the Company
as of September 30, 2023 and 2022, and the results of its operations and its cash flows for each of the two years in the period ended
September 30, 2023, in conformity with accounting principles generally accepted in the United States of America.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">We also have audited, in accordance with the standards of the Public Company
Accounting Oversight Board (United States) (&#8220;PCAOB&#8221;), the Company&#8217;s internal control over financial reporting as of
September 30, 2023, based on criteria established in the 2013 Internal Control - Integrated Framework issued by the Committee of Sponsoring
Organizations of the Treadway Commission (&#8220;COSO&#8221;), and our report dated November 27, 2023 expressed an unqualified opinion.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0">Basis for opinion</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">These financial statements are the responsibility of the Company&#8217;s
management. Our responsibility is to express an opinion on the Company&#8217;s financial statements based on our audits. We are a public
accounting firm registered with the PCAOB and are required to be independent with respect to the Company in accordance with the U.S. federal
securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">We conducted our audits in accordance with the standards of the PCAOB.
Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free
of material misstatement, whether due to error or fraud. Our audits included performing procedures to assess the risks of material misstatement
of the financial statements, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included
examining, on a test basis, evidence regarding the amounts and disclosures in the financial statements. Our audits also included evaluating
the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the financial
statements. We believe that our audits provide a reasonable basis for our opinion.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0">Critical audit matters</p>

<p style="font: bold 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">Critical audit matters are matters arising from the current period audit
of the financial statements that were communicated or required to be communicated to the audit committee and that: (1) relate to accounts
or disclosures that are material to the financial statements and (2) involved our especially challenging, subjective, or complex judgments.
We determined that there are no critical audit matters.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">/s/ <span id="xdx_906_edei--AuditorName_c20221001__20230930_zO17DJehTIh7"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:AuditorName">GRANT THORNTON LLP</ix:nonNumeric></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">We have served as the Company&#8217;s auditor since 2022.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span id="xdx_90B_edei--AuditorLocation_c20221001__20230930_zy0ufrpzjCdb"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:AuditorLocation">Melville, New York</ix:nonNumeric></span><br />
November 27, 2023</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0">&#160;<span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: Black">&#160;</span><span id="xdx_901_edei--AuditorFirmId_c20221001__20230930_z1fULQvPTV13" style="display: none"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="dei:AuditorFirmId">248</ix:nonNumeric></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: Black"></span></p>

<!-- Field: Page; Sequence: 70; Value: 1 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->3<!-- Field: /Sequence --></p></div>
    <div style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: Black">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center; color: fuchsia"><span style="color: Black"><b>Report
of Independent Registered Public Accounting Firm</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><span style="color: Black"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><span style="color: Black">Shareholders
and Board of Directors</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><span style="color: Black">Anavex
Life Sciences Corp.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0in; color: fuchsia"><span style="color: Black">New
York, New York</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0in; color: fuchsia"><span style="color: Black">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0in; color: fuchsia"><span style="color: Black"><b>Opinion
on the Consolidated Financial Statements</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0in; color: fuchsia"><span style="color: Black"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0in; color: fuchsia"><span style="color: Black">We
have audited the consolidated statements of operations and comprehensive loss, stockholders&#8217; equity, and cash flows for the year
ended September 30, 2021, and the related notes (collectively referred to as the &#8220;consolidated financial statements&#8221;) of
Anavex Life Sciences Corp. (the &#8220;Company&#8221;). In our opinion, the consolidated financial statements present fairly, in all
material respects, the results of the Company&#8217;s operations and cash flows for the year ended September 30, 2021<b>,</b> in conformity
with accounting principles generally accepted in the United States of America.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0in; color: fuchsia"><span style="color: Black">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0in; color: fuchsia"><span style="color: Black"><b>Basis
for Opinion</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0in; color: fuchsia"><span style="color: Black"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0in; color: fuchsia"><span style="color: Black">These
consolidated financial statements are the responsibility of the Company&#8217;s management. Our responsibility is to express an opinion
on the Company&#8217;s consolidated financial statements based on our audit. We are a public accounting firm registered with the PCAOB
and are required to be independent with respect to the Company in accordance with the U.S. federal securities laws and the applicable
rules and regulations of the Securities and Exchange Commission and the PCAOB.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0in; color: fuchsia"><span style="color: Black">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><span style="color: Black">We conducted
our audit in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable
assurance about whether the consolidated financial statements are free of material misstatement, whether due to error or fraud.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><span style="color: Black">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="color: Black">Our audit included performing
procedures to assess the risks of material misstatement of the consolidated financial statements, whether due to error or fraud, and
performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts
and disclosures in the consolidated financial statements. Our audit also included evaluating the accounting principles used and significant
estimates made by management, as well as evaluating the overall presentation of the consolidated financial statements. We believe that
our audit provides a reasonable basis for our opinion.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><span style="color: Black">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0in; color: fuchsia"><span style="color: Black"><b>Critical
Audit Matters</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><span style="color: Black"><i>&#160;</i></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="color: Black">Critical audit matters
are matters arising from the current period audit of the consolidated financial statements that were communicated or required to be communicated
to the audit committee and that: (1) relate to accounts or disclosures that are material to the consolidated financial statements and
(2) involved our especially challenging, subjective, or complex judgments. We determined that there are no critical audit matters.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="color: Black">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="color: Black">/s/ BDO USA, P.C.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="color: Black">We served as the Company's
auditor from 2013 to 2022.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><span style="color: Black">New York,
New York</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><span style="color: Black">November
24, 2021</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><span style="color: Black">&#160;<span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b></b></span></p>

<!-- Field: Page; Sequence: 71; Value: 1 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->4<!-- Field: /Sequence --></p></div>
    <div style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10.5pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Anavex
Life Sciences Corp.</b></span></p>

<p style="font: 10.5pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Consolidated Balance Sheets</b></span></p>

<p style="font: 10.5pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>(in
thousands, except share and per share amounts)</b></span></p>

<p style="font: 12pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 12pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>

<table cellpadding="0" cellspacing="0" id="xdx_30B_111_pn3n3_zQZltIyEyEde" summary="xdx: Statement - Consolidated Balance Sheets" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: center">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td id="xdx_498_20230930_zCmYdRkCgrOg" style="text-align: center">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td id="xdx_497_20220930_zpOmZLDovIxi" style="text-align: center">&#160;</td>
<td style="text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="7" style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September 30,</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_407_eus-gaap--AssetsAbstract_iB_zvRIiyPgrRIb" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Assets</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_409_eus-gaap--AssetsCurrentAbstract_i01B_zsGTsQSAZSya" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Current</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_400_eus-gaap--CashAndCashEquivalentsAtCarryingValue_i02I_maAzfjx_zM1C0zGPRv3d" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 20pt; width: 56%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Cash and cash equivalents</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; width: 8%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; width: 12%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:CashAndCashEquivalentsAtCarryingValue" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">151,024</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; width: 8%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; width: 12%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:CashAndCashEquivalentsAtCarryingValue" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">149,158</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_409_eus-gaap--IncomeTaxesReceivable_i02I_maAzfjx_z2uA6SBHf0I3" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 20pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Incentive and tax receivables</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncomeTaxesReceivable" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">2,709</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncomeTaxesReceivable" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">3,193</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40D_eus-gaap--PrepaidExpenseAndOtherAssetsCurrent_i02I_maAzfjx_zzyD2nNrsrF5" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 20pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Prepaid expenses and other current assets</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:PrepaidExpenseAndOtherAssetsCurrent" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">653</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:PrepaidExpenseAndOtherAssetsCurrent" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">354</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40C_eus-gaap--Assets_i01TI_mtAzfjx_z5ALXFOzRM9g" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total Assets</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:Assets" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">154,386</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:Assets" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">152,705</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_407_eus-gaap--LiabilitiesAndStockholdersEquityAbstract_iB_zYUHGBBAkn78" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Liabilities and Stockholders' Equity</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40C_eus-gaap--LiabilitiesCurrentAbstract_i01B_zBMzmo9InzDa" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Current Liabilities</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_408_eus-gaap--AccountsPayableCurrent_i02I_maLzxfz_zRBDvF7ZqlU7" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 20pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accounts payable</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AccountsPayableCurrent" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">4,322</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AccountsPayableCurrent" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">3,825</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_404_eus-gaap--AccruedLiabilitiesCurrent_i02I_maLzxfz_z1w1CKW6uXz2" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 20pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accrued liabilities - Note 3</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AccruedLiabilitiesCurrent" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">7,295</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AccruedLiabilitiesCurrent" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">5,945</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40F_eus-gaap--DeferredRentCredit_i02I_maLzxfz_zjPe8ZFs8LP4" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 20pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Deferred grant income - Note 4</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredRentCredit" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">917</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredRentCredit" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">444</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40E_eus-gaap--Liabilities_i02TI_mtLzxfz_maLASEzrJ6_zMTap6XnHsJ9" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total Liabilities</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:Liabilities" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">12,534</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:Liabilities" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">10,214</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_403_eus-gaap--CommitmentsAndContingencies_i01I_zM8uX2RC6Ah8" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Commitments and Contingencies - Note 6</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b style="display: none"><span style="-sec-ix-hidden: xdx2ixbrl0084">&#8212;</span></b></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b style="display: none"><span style="-sec-ix-hidden: xdx2ixbrl0085">&#8212;</span></b></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Capital stock</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 20pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Authorized: </span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10pt Times New Roman, Times, Serif; padding: 0pt 0pt 0pt 20pt; text-indent: -10pt"><span id="xdx_90C_eus-gaap--PreferredStockSharesAuthorized_iI_pip0_c20230930_z54gQhh20Zs4" title="Preferred stock, authorized"><span id="xdx_907_eus-gaap--PreferredStockSharesAuthorized_iI_pip0_c20220930_zxWKc5UTBzdc" title="Preferred stock, authorized"><ix:nonFraction name="us-gaap:PreferredStockSharesAuthorized" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares"><ix:nonFraction name="us-gaap:PreferredStockSharesAuthorized" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">10,000,000</ix:nonFraction></ix:nonFraction></span></span> preferred stock, par value $<span id="xdx_907_eus-gaap--PreferredStockParOrStatedValuePerShare_iI_pip0_c20230930_ze1L6xhxz0j6" title="Preferred stock, par value"><span id="xdx_905_eus-gaap--PreferredStockParOrStatedValuePerShare_iI_pip0_c20220930_zmJeja1dHdbd" title="Preferred stock, par value"><ix:nonFraction name="us-gaap:PreferredStockParOrStatedValuePerShare" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares"><ix:nonFraction name="us-gaap:PreferredStockParOrStatedValuePerShare" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">0.001</ix:nonFraction></ix:nonFraction></span></span> per share</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td id="xdx_981_eus-gaap--PreferredStockValue_i01I_pp0p0_maSEzBzy_c20230930_z8RYaJ0FGUmc" title="Capital stock Authorized:10,000,000 preferred stock, par value $0.001 per share" style="text-align: right"><b style="display: none"><span style="-sec-ix-hidden: xdx2ixbrl0095">&#8212;</span></b></td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td id="xdx_98E_eus-gaap--PreferredStockValue_i01I_pp0p0_maSEzBzy_c20220930_zWL24RGTqWi5" title="Capital stock Authorized:10,000,000 preferred stock, par value $0.001 per share" style="text-align: right"><b style="display: none"><span style="-sec-ix-hidden: xdx2ixbrl0097">&#8212;</span></b></td>
<td style="text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="font: 10pt Times New Roman, Times, Serif; padding: 0pt 0pt 0pt 20pt; text-indent: -10pt"><span id="xdx_901_eus-gaap--CommonStockSharesAuthorized_iI_pip0_c20230930_zYsk4JilSgah" title="Common shares, authorized"><span id="xdx_90F_eus-gaap--CommonStockSharesAuthorized_iI_pip0_c20220930_zStX7RPvMiXf" title="Common shares, authorized"><ix:nonFraction name="us-gaap:CommonStockSharesAuthorized" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares"><ix:nonFraction name="us-gaap:CommonStockSharesAuthorized" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">200,000,000</ix:nonFraction></ix:nonFraction></span></span> common stock, par value $<span id="xdx_906_eus-gaap--CommonStockParOrStatedValuePerShare_iI_pip0_c20230930_zuq9Ib8rV2Xk" title="Common shares, par value"><span id="xdx_904_eus-gaap--CommonStockParOrStatedValuePerShare_iI_pip0_c20220930_z0tsECBLBTA2" title="Common shares, par value"><ix:nonFraction name="us-gaap:CommonStockParOrStatedValuePerShare" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares"><ix:nonFraction name="us-gaap:CommonStockParOrStatedValuePerShare" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">0.001</ix:nonFraction></ix:nonFraction></span></span> per share</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right"></td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right"></td>
<td style="text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 20pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Issued and outstanding: <br /><span id="xdx_904_eus-gaap--CommonStockSharesIssued_iI_pip0_c20230930_zMdDOM0WHRld" title="Common shares, issued"><span id="xdx_903_eus-gaap--CommonStockSharesOutstanding_iI_pip0_c20230930_ztQYG0jG6JUa" title="Common shares, outstanding"><ix:nonFraction name="us-gaap:CommonStockSharesIssued" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares"><ix:nonFraction name="us-gaap:CommonStockSharesOutstanding" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">82,066,511</ix:nonFraction></ix:nonFraction></span></span> common shares (2022 - <span id="xdx_907_eus-gaap--CommonStockSharesIssued_iI_pip0_c20220930_z2aQQtKGQ8dg" title="Common shares, issued"><span id="xdx_90C_eus-gaap--CommonStockSharesOutstanding_iI_pip0_c20220930_zZz8noERfQSa" title="Common shares, outstanding"><ix:nonFraction name="us-gaap:CommonStockSharesIssued" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares"><ix:nonFraction name="us-gaap:CommonStockSharesOutstanding" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">77,942,815</ix:nonFraction></ix:nonFraction></span></span>)</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--CommonStockValue_iI_maSEzBzy_c20230930_zpfU6OVALuXb" title="Capital stock Authorized: 200,000,000 common stock, par value $0.001 per Issued and outstanding: 82,066,511 common shares (2022 - 77,942,815)" style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:CommonStockValue" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">82</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_981_eus-gaap--CommonStockValue_iI_maSEzBzy_c20220930_zUdOFgi2eQgf" title="Capital stock Authorized: 200,000,000 common stock, par value $0.001 per Issued and outstanding: 82,066,511 common shares (2022 - 77,942,815)" style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:CommonStockValue" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">78</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40B_eus-gaap--AdditionalPaidInCapitalCommonStock_iI_maSEzBzy_zqfQZaGYu2u1" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Additional paid-in capital</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AdditionalPaidInCapitalCommonStock" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">434,839</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AdditionalPaidInCapitalCommonStock" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">387,977</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_405_eus-gaap--RetainedEarningsAccumulatedDeficit_iI_maSEzBzy_zDI9UEtfotx2" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accumulated deficit</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:RetainedEarningsAccumulatedDeficit" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">293,069</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:RetainedEarningsAccumulatedDeficit" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">245,564</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_402_eus-gaap--StockholdersEquity_iTI_mtSEzBzy_maLASEzrJ6_zNk3RyfDX2jj" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total Stockholders' Equity</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">141,852</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">142,491</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_408_eus-gaap--LiabilitiesAndStockholdersEquity_iTI_mtLASEzrJ6_zB0Wsk2TGTe8" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total Liabilities and Stockholders' Equity</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:LiabilitiesAndStockholdersEquity" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">154,386</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:LiabilitiesAndStockholdersEquity" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">152,705</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



<p style="font: 12pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">See
Accompanying Notes to Consolidated Financial Statements</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b></b></span></p>

<!-- Field: Page; Sequence: 72; Value: 1 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->5<!-- Field: /Sequence --></p></div>
    <div style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Anavex
Life Sciences Corp.</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Consolidated
Statements of Operations and Comprehensive Loss</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>(in
thousands, except share and per share amounts)</b></span></p>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b></b></span></p>


<table cellpadding="0" cellspacing="0" id="xdx_30D_113_pn3n3_z7U10QngU7Kc" summary="xdx: Statement - Consolidated Statements of Operations and Comprehensive Loss" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: center">&#160;</td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif">&#160;</td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left">&#160;</td>
<td id="xdx_490_20221001__20230930_zQaVFGd5JuY1" style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: center">&#160;</td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left">&#160;</td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif">&#160;</td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left">&#160;</td>
<td id="xdx_497_20211001__20220930_zxwvQyNT4lli" style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: center">&#160;</td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left">&#160;</td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif">&#160;</td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left">&#160;</td>
<td id="xdx_49B_20201001__20210930_zr2tYS1P8xBb" style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: center">&#160;</td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="11" style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Years
Ended September 30,</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr id="xdx_40F_eus-gaap--OperatingExpensesAbstract_iB_zorUsnHbzOYd" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Operating
expenses</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_403_eus-gaap--GeneralAndAdministrativeExpense_i01_maCzoQo_msOILzD6j_zLaDL0oTeBJ5" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">General
and administrative</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:GeneralAndAdministrativeExpense" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">12,039</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:GeneralAndAdministrativeExpense" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">13,070</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:GeneralAndAdministrativeExpense" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">9,018</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40E_eus-gaap--ResearchAndDevelopmentExpense_i01_maCzoQo_msOILzD6j_zpp3l9jbiDj4" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ResearchAndDevelopmentExpense" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">43,717</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ResearchAndDevelopmentExpense" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">37,916</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ResearchAndDevelopmentExpense" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">32,984</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_401_eus-gaap--OperatingExpenses_i01T_mtCzoQo_msOILzfCM_zAZuE4rYE2i6" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total
operating expenses</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:OperatingExpenses" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">55,756</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:OperatingExpenses" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">50,986</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:OperatingExpenses" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">42,002</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_404_eus-gaap--OperatingIncomeLoss_i01T_mtOILzfCM_maILFCOz5FW_zDczw31Q4Qle" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Operating
loss</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:OperatingIncomeLoss" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">55,756</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:OperatingIncomeLoss" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">50,986</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:OperatingIncomeLoss" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">42,002</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40A_eus-gaap--NonoperatingIncomeExpenseAbstract_iB_zerw1dpevIq2" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Other
income (expenses)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40C_ecustom--NonOperatingIncomeFromGrants_i01_maNIEz6Gr_zDXRY3zuD8Ua" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Grant
income</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:NonOperatingIncomeFromGrants" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">25</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0156">&#8212;</span></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:NonOperatingIncomeFromGrants" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">54</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_408_ecustom--ResearchAndDevelopmentIncentiveIncome_i01_maNIEz6Gr_zygkiphvHuT3" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development incentive income</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:ResearchAndDevelopmentIncentiveIncome" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">2,718</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:ResearchAndDevelopmentIncentiveIncome" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">3,323</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:ResearchAndDevelopmentIncentiveIncome" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">4,547</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40E_eus-gaap--InterestIncomeExpenseNet_i01_maNIEz6Gr_zHH8yG1bGLHg" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Interest
income, net</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:InterestIncomeExpenseNet" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">6,519</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:InterestIncomeExpenseNet" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">947</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:InterestIncomeExpenseNet" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">26</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_401_ecustom--OtherFinancingExpense_i01N_di_msNIEz6Gr_zUCwdvxRI70i" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Other
financing expense</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="avxl:OtherFinancingExpense" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">964</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0168">&#8212;</span></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0169">&#8212;</span></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40C_eus-gaap--ForeignCurrencyTransactionGainLossBeforeTax_i01_maNIEz6Gr_zvm0PxiTmHwh" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Foreign
exchange loss</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:ForeignCurrencyTransactionGainLossBeforeTax" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">40</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:ForeignCurrencyTransactionGainLossBeforeTax" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">904</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:ForeignCurrencyTransactionGainLossBeforeTax" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">266</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_409_eus-gaap--NonoperatingIncomeExpense_i01T_mtNIEz6Gr_maILFCOz5FW_zj06UzSFUhKb" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total
other income, net</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:NonoperatingIncomeExpense" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">8,258</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:NonoperatingIncomeExpense" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">3,366</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:NonoperatingIncomeExpense" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">4,361</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_405_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_i01T_mtILFCOz5FW_maNILzQFo_zFjM9xUXfJnl" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net
loss before provision for income taxes</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">47,498</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">47,620</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">37,641</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_404_eus-gaap--CurrentIncomeTaxExpenseBenefit_iN_di_msNILzQFo_znXYrgKNj8Da" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Income
tax expense, current</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:CurrentIncomeTaxExpenseBenefit" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">7</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:CurrentIncomeTaxExpenseBenefit" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">358</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:CurrentIncomeTaxExpenseBenefit" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">268</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_400_eus-gaap--NetIncomeLoss_mtNILzQFo_z63Go4Y6mM33" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net
loss and comprehensive loss</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">47,505</ix:nonFraction></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">47,978</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">37,909</ix:nonFraction></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_402_ecustom--EarningPerShareBasicAndDilutedAbstract_iB_z0oeZw105nqe" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net
Loss per share <br />Basic and diluted</span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 10.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_900_eus-gaap--EarningsPerShareBasic_pip0_c20221001__20230930_zaaehFijrqr8" title="Net Loss per share, Basic"><span id="xdx_907_eus-gaap--EarningsPerShareDiluted_pip0_c20221001__20230930_zdJlYSBValZd" title="Net Loss per share, Diluted">(<ix:nonFraction name="us-gaap:EarningsPerShareBasic" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" sign="-" unitRef="USDPShares"><ix:nonFraction name="us-gaap:EarningsPerShareDiluted" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" sign="-" unitRef="USDPShares">0.60</ix:nonFraction></ix:nonFraction></span></span></span></td>
<td style="font: bold 10.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_909_eus-gaap--EarningsPerShareBasic_pip0_c20211001__20220930_zKzKBFccUHgf" title="Net Loss per share, Basic"><span id="xdx_90F_eus-gaap--EarningsPerShareDiluted_pip0_c20211001__20220930_zhjdG0zhjtuf" title="Net Loss per share, Diluted">(<ix:nonFraction name="us-gaap:EarningsPerShareBasic" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" sign="-" unitRef="USDPShares"><ix:nonFraction name="us-gaap:EarningsPerShareDiluted" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" sign="-" unitRef="USDPShares">0.62</ix:nonFraction></ix:nonFraction></span></span></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_909_eus-gaap--EarningsPerShareBasic_pip0_c20201001__20210930_zjTFRXb9uPR5" title="Net Loss per share, Basic"><span id="xdx_90D_eus-gaap--EarningsPerShareDiluted_pip0_c20201001__20210930_z3Gp1OSVEqS1" title="Net Loss per share, Diluted">(<ix:nonFraction name="us-gaap:EarningsPerShareBasic" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" sign="-" unitRef="USDPShares"><ix:nonFraction name="us-gaap:EarningsPerShareDiluted" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" sign="-" unitRef="USDPShares">0.54</ix:nonFraction></ix:nonFraction></span></span></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40D_eus-gaap--WeightedAverageNumberOfSharesOutstandingAbstract_iB" style="vertical-align: bottom; background-color: White">
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted
average number of shares outstanding <br />Basic and diluted</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_907_eus-gaap--WeightedAverageNumberOfSharesOutstandingBasic_pip0_c20221001__20230930_zqF1OZQUEy3" title="Weighted average number of shares outstanding, Basic"><span id="xdx_90B_eus-gaap--WeightedAverageNumberOfDilutedSharesOutstanding_pip0_c20221001__20230930_zfpyBGdGeHid" title="Weighted average number of shares outstanding, Diluted"><ix:nonFraction name="us-gaap:WeightedAverageNumberOfSharesOutstandingBasic" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares"><ix:nonFraction name="us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">79,787,596</ix:nonFraction></ix:nonFraction></span></span></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_909_eus-gaap--WeightedAverageNumberOfSharesOutstandingBasic_pip0_c20211001__20220930_znXswLxBKwN9" title="Weighted average number of shares outstanding, Basic"><span id="xdx_901_eus-gaap--WeightedAverageNumberOfDilutedSharesOutstanding_pip0_c20211001__20220930_zXbfwtXltgzg" title="Weighted average number of shares outstanding, Diluted"><ix:nonFraction name="us-gaap:WeightedAverageNumberOfSharesOutstandingBasic" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares"><ix:nonFraction name="us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">76,909,993</ix:nonFraction></ix:nonFraction></span></span></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 10.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_906_eus-gaap--WeightedAverageNumberOfSharesOutstandingBasic_pip0_c20201001__20210930_zscWBGXpYOH6" title="Weighted average number of shares outstanding, Basic"><span id="xdx_908_eus-gaap--WeightedAverageNumberOfDilutedSharesOutstanding_pip0_c20201001__20210930_zTQdqcMhfLf8" title="Weighted average number of shares outstanding, Diluted"><ix:nonFraction name="us-gaap:WeightedAverageNumberOfSharesOutstandingBasic" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares"><ix:nonFraction name="us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">69,802,960</ix:nonFraction></ix:nonFraction></span></span></span></td>
<td style="font: 10.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span><b></b></p><p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">See
Accompanying Notes to Consolidated Financial Statements</span></p>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b></b></span></p>

<!-- Field: Page; Sequence: 73; Value: 1 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->6<!-- Field: /Sequence --></p></div>
    <div style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 9.5pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Anavex
Life Sciences Corp.</b></span></p>

<p style="font: 9.5pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>For
the years ended September 30, 2023, 2022 and 2021</b></span></p>

<p style="font: 9.5pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>(in
thousands, except share and per share amounts)</b></span></p>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;&#160;</b></span></p>

<table cellpadding="0" cellspacing="0" id="xdx_304_112_pn3n3_zB1WTT66iq74" summary="xdx: Statement - Consolidated Statements of Cash Flows" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom; background-color: White">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: center">&#160;</td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif">&#160;</td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left">&#160;</td>
<td id="xdx_497_20221001__20230930_zuUCJrcfXUA9" style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: center">&#160;</td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left">&#160;</td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif">&#160;</td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left">&#160;</td>
<td id="xdx_492_20211001__20220930_zCwtH2e9U392" style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: center">&#160;</td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left">&#160;</td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif">&#160;</td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left">&#160;</td>
<td id="xdx_49C_20201001__20210930_zKsuKjdPGyvl" style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: center">&#160;</td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="11" style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Years ended September 30,</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font: bold 9.5pt Times New Roman, Times, Serif; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_402_eus-gaap--NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_iB_zmyjESWHlCSe" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: bold 9.5pt Times New Roman, Times, Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Cash
Flows used in Operating Activities</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40D_eus-gaap--NetIncomeLoss_i01_maCzkH4_msCPFSAzSld_maNCPBUzy3C_z79t9eZTCb4k" style="vertical-align: bottom; background-color: White">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net
loss</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">47,505</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">47,978</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">37,909</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_402_eus-gaap--AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_i01B_z5I7U1QPVPBl" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Adjustments
to reconcile net loss to net cash used in operations:</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40E_ecustom--NoncashFinancingRelatedCharges_i01_maCPFSAzSld_maNCPBUzy3C_z2NZl9QKh7u" style="vertical-align: bottom; background-color: White">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 20pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Non-cash
financing related charges</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:NoncashFinancingRelatedCharges" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">845</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0236">&#8212;</span></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 10pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0237">&#8212;</span></span></td>
<td style="font: 10pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40D_eus-gaap--ShareBasedCompensation_i01_maCzkH4_maCPFSAzSld_maNCPBUzy3C_zvyKH7FdTdEa" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 20pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Stock-based
compensation</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensation" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">16,370</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensation" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">18,379</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensation" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">8,231</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_404_eus-gaap--IncreaseDecreaseInOperatingCapitalAbstract_i01B_zOx8w2dBt4Nf" style="vertical-align: bottom; background-color: White">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Changes
in working capital balances related to operations:</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_401_eus-gaap--IncreaseDecreaseInIncomeTaxesReceivable_i02N_di_msNCPBUzy3C_z0Ky9FT3lly7" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 20pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Incentive
and tax receivables</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncreaseDecreaseInIncomeTaxesReceivable" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">484</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncreaseDecreaseInIncomeTaxesReceivable" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">5,944</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncreaseDecreaseInIncomeTaxesReceivable" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">4,287</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_409_eus-gaap--IncreaseDecreaseInPrepaidExpense_i02N_di_msNCPBUzy3C_zLICLGzJZSie" style="vertical-align: bottom; background-color: White">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 20pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Prepaid
expenses and deposits</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncreaseDecreaseInPrepaidExpense" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">299</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncreaseDecreaseInPrepaidExpense" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">1</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncreaseDecreaseInPrepaidExpense" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">88</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40A_eus-gaap--IncreaseDecreaseInAccountsPayable_i02_maNCPBUzy3C_zQ1wiOHw7fY3" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 30pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accounts
payable</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncreaseDecreaseInAccountsPayable" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">497</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncreaseDecreaseInAccountsPayable" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">914</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncreaseDecreaseInAccountsPayable" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">751</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40C_eus-gaap--IncreaseDecreaseInAccruedLiabilities_i02_maNCPBUzy3C_zH5jVp0WsVNk" style="vertical-align: bottom; background-color: White">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 20pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accrued
liabilities</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncreaseDecreaseInAccruedLiabilities" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,350</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncreaseDecreaseInAccruedLiabilities" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">330</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncreaseDecreaseInAccruedLiabilities" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">2,298</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_409_ecustom--DeferredGrantIncome_i02N_di_msNCPBUzy3C_zcTGzxzSHO84" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 20pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Deferred
grant income</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:DeferredGrantIncome" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">473</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0264">&#8212;</span></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:DeferredGrantIncome" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">444</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_402_eus-gaap--NetCashProvidedByUsedInOperatingActivities_i02T_mtNCPBUzy3C_maCCERCz2Xn_zTNo50UCMWcj" style="vertical-align: bottom; background-color: White">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net
cash used in operating activities</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:NetCashProvidedByUsedInOperatingActivities" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">27,785</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:NetCashProvidedByUsedInOperatingActivities" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">24,238</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:NetCashProvidedByUsedInOperatingActivities" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">30,384</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40C_eus-gaap--NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_iB_zgm4FJctQZC5" style="vertical-align: bottom; background-color: White">
<td style="font: bold 9.5pt Times New Roman, Times, Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Cash
Flows provided by Financing Activities</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_406_eus-gaap--ProceedsFromIssuanceOfCommonStock_i01_maNCPBUznG6_zADUAMvMOTUe" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Issuance
of common shares</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ProceedsFromIssuanceOfCommonStock" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">27,875</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ProceedsFromIssuanceOfCommonStock" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">20,985</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ProceedsFromIssuanceOfCommonStock" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">153,219</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40D_eus-gaap--PaymentsOfStockIssuanceCosts_i01N_di_msNCPBUznG6_zvELUPlQJko9" style="vertical-align: bottom; background-color: White">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Share
issue costs</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0279">&#8212;</span></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:PaymentsOfStockIssuanceCosts" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">707</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:PaymentsOfStockIssuanceCosts" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">5,551</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_402_eus-gaap--ProceedsFromWarrantExercises_i01_maNCPBUznG6_zlOSXBnQoJm2" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Proceeds
from exercise of warrants</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0283">&#8212;</span></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0284">&#8212;</span></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ProceedsFromWarrantExercises" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,467</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40C_eus-gaap--ProceedsFromStockOptionsExercised_i01_maNCPBUznG6_zpYR4EQ2bmej" style="vertical-align: bottom; background-color: White">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Proceeds
from exercise of stock options</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ProceedsFromStockOptionsExercised" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,776</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ProceedsFromStockOptionsExercised" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,010</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ProceedsFromStockOptionsExercised" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">4,108</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40F_eus-gaap--NetCashProvidedByUsedInFinancingActivities_i01T_mtNCPBUznG6_maCCERCz2Xn_zBH03x9IR6ea" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net
cash provided by financing activities</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:NetCashProvidedByUsedInFinancingActivities" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">29,651</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:NetCashProvidedByUsedInFinancingActivities" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">21,288</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:NetCashProvidedByUsedInFinancingActivities" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">153,243</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40C_eus-gaap--CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect_iT_mtCCERCz2Xn_zisCW6P2eep3" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Increase
in cash and cash equivalents during the period</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,866</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">2,950</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">122,859</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_409_eus-gaap--CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_iS_zOaZmEmxCHJh" style="vertical-align: bottom; background-color: White">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Cash
and cash equivalents, beginning of period</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">149,158</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" contextRef="AsOf2021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">152,108</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" contextRef="AsOf2020-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">29,249</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_409_eus-gaap--CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_iE_zysPwf4b1x52" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: bold 9.5pt Times New Roman, Times, Serif; padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Cash
and cash equivalents, end of period</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">151,024</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">149,158</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" contextRef="AsOf2021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">152,108</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40F_eus-gaap--SupplementalCashFlowInformationAbstract_iB_zDTC64RaBx9i" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font: bold 9.5pt Times New Roman, Times, Serif; padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Supplemental
Cash Flow Information</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_409_ecustom--CashPaidForStateAndLocalMinimumIncomeTaxes_i01_zMJTzBh0zha1" style="vertical-align: bottom; background-color: White">
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Cash
paid for state and local minimum income taxes</span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font: bold 9.5pt Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font: bold 9.5pt Times New Roman, Times, Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:CashPaidForStateAndLocalMinimumIncomeTaxes" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">136</ix:nonFraction></span></td>
<td style="font: bold 9.5pt Times New Roman, Times, Serif; padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:CashPaidForStateAndLocalMinimumIncomeTaxes" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">327</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font: 9.5pt Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:CashPaidForStateAndLocalMinimumIncomeTaxes" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">140</ix:nonFraction></span></td>
<td style="font: 9.5pt Arial, Helvetica, Sans-Serif; padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">See
Accompanying Notes to Consolidated Financial Statements</span></p>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b></b></span></p>

<!-- Field: Page; Sequence: 74; Value: 1 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->7<!-- Field: /Sequence --></p></div>
    <div style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Anavex
Life Sciences Corp.</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Consolidated
Statements of Changes in Stockholders' Equity</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>(in thousands, except share and per share amounts)</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>

<table cellpadding="0" cellspacing="0" id="xdx_30C_114_pn3n3_z9DaNnFsOA62" summary="xdx: Statement - Consolidated Statements of Changes in Stockholders&apos; Equity" style="font: 10.5pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: center; font-size: 10pt">&#160;</td>
<td style="font-size: 10pt">&#160;</td>
<td style="font-size: 10pt; text-align: left">&#160;</td>
<td style="font-size: 10pt; text-align: right">&#160;</td>
<td style="font-size: 10pt; text-align: left">&#160;</td>
<td style="font-size: 10pt">&#160;</td>
<td style="font-size: 10pt; text-align: left">&#160;</td>
<td id="xdx_4B4_us-gaap--StatementEquityComponentsAxis_us-gaap--CommonStockMember_zgZJ8GtirFSf" style="font-size: 10pt; text-align: center">&#160;</td>
<td style="font-size: 10pt; text-align: left">&#160;</td>
<td style="font-size: 10pt">&#160;</td>
<td style="font-size: 10pt; text-align: left">&#160;</td>
<td id="xdx_4B7_us-gaap--StatementEquityComponentsAxis_us-gaap--AdditionalPaidInCapitalMember_zov0mLSYgIn9" style="font-size: 10pt; text-align: center">&#160;</td>
<td style="font-size: 10pt; text-align: left">&#160;</td>
<td style="font-size: 10pt">&#160;</td>
<td style="font-size: 10pt; text-align: left">&#160;</td>
<td id="xdx_4BF_us-gaap--StatementEquityComponentsAxis_us-gaap--RetainedEarningsMember_zMc7V7KfyIH1" style="font-size: 10pt; text-align: center">&#160;</td>
<td style="font-size: 10pt; text-align: left">&#160;</td>
<td style="font-size: 10pt">&#160;</td>
<td style="font-size: 10pt; text-align: left">&#160;</td>
<td id="xdx_4BD_zkLwZo7rn9Ve" style="font-size: 10pt; text-align: center">&#160;</td>
<td style="font-size: 10pt; text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common
Stock</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Additional
Paid-</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accumulated</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Shares</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Par
Value</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">in
Capital</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Deficit</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_43D_c20201001__20210930_eus-gaap--StockholdersEquity_iS_zKFrjI4j7ogd" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 35%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Balance,
October 1, 2020</span></td>
<td style="width: 2%; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--SharesOutstanding_iS_pip0_c20201001__20210930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_znUxRzbJlb58" title="Balance at beginning, shares" style="width: 9%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:SharesOutstanding" contextRef="AsOf2020-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">62,045,198</ix:nonFraction></span></td>
<td style="width: 1%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 9%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2020-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">62</ix:nonFraction></span></td>
<td style="width: 1%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 9%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2020-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">186,852</ix:nonFraction></span></td>
<td style="width: 1%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 9%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2020-09-30_us-gaap_RetainedEarningsMember" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">159,677</ix:nonFraction></span></td>
<td style="width: 1%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="width: 2%; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 9%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2020-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">27,237</ix:nonFraction></span></td>
<td style="width: 1%; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Shares
issued under 2019 purchase agreement </span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40F_eus-gaap--StockRepurchasedDuringPeriodValue_zKPR9ecWnhte" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 20pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Purchase
shares</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--StockRepurchasedDuringPeriodShares_pip0_c20201001__20210930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_zYYXEr2ke59d" title="Purchase shares, shares" style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockRepurchasedDuringPeriodShares" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">4,007,996</ix:nonFraction></span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span><ix:nonFraction name="us-gaap:StockRepurchasedDuringPeriodValue" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">4</ix:nonFraction></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockRepurchasedDuringPeriodValue" contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">24,107</ix:nonFraction></span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;<span style="-sec-ix-hidden: xdx2ixbrl0324">&#8212;</span></span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="display: none; font-size: 10pt; text-align: right"><span style="-sec-ix-hidden: xdx2ixbrl0325">&#8212;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span>24,111</td>
    <td>&#160;</td></tr>
<tr id="xdx_405_ecustom--CommitmentShares_zMdHzzX5a5xj" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 20pt; font-family: Arial, Helvetica, Sans-Serif; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Commitment
shares</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98D_ecustom--CommitmentSharesShares_pip0_c20201001__20210930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_z9VASbN7FbQh" title="Commitment shares, shares" style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:CommitmentSharesShares" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">78,213</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0329">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0330">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0331">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0332">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_401_ecustom--SharesIssuedUnderSalesAgreement_zECw0aOLw457" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Shares
issued under Sales Agreement</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_ecustom--SharesIssuedUnderSalesAgreementShares_pip0_c20201001__20210930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_zfJ1ymCcLYx" title="Shares issued under Sales Agreement, shares" style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedUnderSalesAgreementShares" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">5,634,576</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedUnderSalesAgreement" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">6</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedUnderSalesAgreement" contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">79,102</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0338">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedUnderSalesAgreement" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">79,108</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_407_ecustom--LessSalesAgreementShareIssueCosts_z1foOa9wOwTg" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 20pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Less:
share issue costs</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0343">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="avxl:LessSalesAgreementShareIssueCosts" contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">2,438</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0345">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="avxl:LessSalesAgreementShareIssueCosts" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">2,438</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_406_ecustom--SharesIssuedPursuantToRegisteredDirectOffering_zWSPiVhYGLri" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Shares
issued pursuant to registered direct offering</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_983_ecustom--SharesIssuedPursuantToRegisteredDirectOfferingShares_pip0_c20201001__20210930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_zoIzNp7Hunrf" title="Shares issued pursuant to registered direct offering, shares" style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToRegisteredDirectOfferingShares" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">2,380,953</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToRegisteredDirectOffering" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">2</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToRegisteredDirectOffering" contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">49,998</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0350">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToRegisteredDirectOffering" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">50,000</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40D_ecustom--LessRegisteredDirectOfferingShareIssueCosts_zAltEBur5R7e" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 20pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Less:
share issue costs</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0355">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="avxl:LessRegisteredDirectOfferingShareIssueCosts" contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">3,097</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0357">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="avxl:LessRegisteredDirectOfferingShareIssueCosts" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">3,097</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_405_ecustom--SharesIssuedPursuantToExerciseOfStockOptions_z5s24rPtqBf8" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Shares
issued pursuant to exercise of stock options</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_ecustom--SharesIssuedPursuantToExerciseOfStockOptionsShares_pip0_c20201001__20210930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_zNTsVYLBukXg" title="Shares issued pursuant to exercise of stock options, shares" style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToExerciseOfStockOptionsShares" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">1,421,529</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToExerciseOfStockOptions" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToExerciseOfStockOptions" contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">4,107</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0362">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToExerciseOfStockOptions" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">4,108</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_400_ecustom--SharesIssuedPusuantToExerciseOfWarrants_zr9zjDba3Jsd" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Shares
issued pursuant to exercise of warrants</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_ecustom--SharesIssuedPusuantToExerciseOfWarrantsShares_pip0_c20201001__20210930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_zmiO1Hj82ppi" title="Shares issued pusuant to exercise of warrants, shares" style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPusuantToExerciseOfWarrantsShares" contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">350,000</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0367">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPusuantToExerciseOfWarrants" contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,466</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0369">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPusuantToExerciseOfWarrants" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,466</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_405_eus-gaap--AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_znalvXF7gmW2" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Share
based compensation</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0374">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">8,231</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0376">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">8,231</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_401_eus-gaap--NetIncomeLoss_zQmGMPJA6X1l" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 1pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net
loss</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0379">&#8212;</span></span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0380">&#8212;</span></span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">37,909</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">37,909</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_432_c20211001__20220930_eus-gaap--StockholdersEquity_iS_z6NuF2Ck3CXk" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Balance,
September 30, 2021</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_987_eus-gaap--SharesOutstanding_iS_pip0_c20211001__20220930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_zHfLoCntYUSf" title="Balance at beginning, shares" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:SharesOutstanding" contextRef="AsOf2021-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">75,918,465</ix:nonFraction></span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2021-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">75</ix:nonFraction></span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2021-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">348,328</ix:nonFraction></span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2021-09-30_us-gaap_RetainedEarningsMember" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">197,586</ix:nonFraction></span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">150,817</ix:nonFraction></span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_401_ecustom--SharesIssuedUnderSalesAgreement_zjswAsOBO0re" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Shares
issued under Sales Agreement</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98F_ecustom--SharesIssuedUnderSalesAgreementShares_pip0_c20211001__20220930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_zsstSezEmYp3" title="Shares issued under Sales Agreement, shares" style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedUnderSalesAgreementShares" contextRef="From2021-10-012022-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">1,623,813</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedUnderSalesAgreement" contextRef="From2021-10-012022-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">2</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedUnderSalesAgreement" contextRef="From2021-10-012022-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">20,983</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0393">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedUnderSalesAgreement" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">20,985</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_407_ecustom--LessSalesAgreementShareIssueCosts_zSwk7GQz7WQ8" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Less:
share issue costs</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0398">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="avxl:LessSalesAgreementShareIssueCosts" contextRef="From2021-10-012022-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">723</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0400">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="avxl:LessSalesAgreementShareIssueCosts" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">723</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_405_ecustom--SharesIssuedPursuantToExerciseOfStockOptions_zb5Ar9gw1weh" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Shares
issued pursuant to exercise of stock options</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_981_ecustom--SharesIssuedPursuantToExerciseOfStockOptionsShares_pip0_c20211001__20220930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_z4Riz2oL1U85" title="Shares issued pursuant to exercise of stock options, shares" style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToExerciseOfStockOptionsShares" contextRef="From2021-10-012022-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">400,537</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToExerciseOfStockOptions" contextRef="From2021-10-012022-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToExerciseOfStockOptions" contextRef="From2021-10-012022-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,010</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0405">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToExerciseOfStockOptions" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,011</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_403_eus-gaap--AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_zwX3V27x6wp4" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Share
based compensation</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0410">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" contextRef="From2021-10-012022-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">18,379</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0412">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">18,379</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_402_eus-gaap--NetIncomeLoss_zmxXDiyDb9Kl" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net
loss</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0415">&#8212;</span></span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0416">&#8212;</span></span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2021-10-012022-09-30_us-gaap_RetainedEarningsMember" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">47,978</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">47,978</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_430_c20221001__20230930_eus-gaap--StockholdersEquity_iS_zBuOu5X3Zes3" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Balance,
September 30, 2022</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--SharesOutstanding_iS_pip0_c20221001__20230930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_zskUvXPMksr2" title="Balance at beginning, shares" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:SharesOutstanding" contextRef="AsOf2022-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">77,942,815</ix:nonFraction></span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2022-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">78</ix:nonFraction></span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2022-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">387,977</ix:nonFraction></span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2022-09-30_us-gaap_RetainedEarningsMember" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">245,564</ix:nonFraction></span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">142,491</ix:nonFraction></span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_404_ecustom--SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares_iP3us-gaap--SharesOutstanding_zsPh3uWpC5Ue" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Shares
issued under 2023 purchase agreement<br /> Initial Commitment shares</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98D_ecustom--SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares_iP3custom--SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares_pip0_c20221001__20230930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_zWjElVfPqWMc" title="Shares issued under 2023 purchase agreement Initial Commitment shares, shares" style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares" contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">75,000</ix:nonFraction></span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0427">&#8212;</span></span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares" contextRef="From2022-10-012023-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">845</ix:nonFraction></span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0429">&#8212;</span></span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">845</ix:nonFraction></span></td>
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_406_eus-gaap--StockRepurchasedDuringPeriodValue_zwLIuFmp6hFd" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 20pt; font-family: Arial, Helvetica, Sans-Serif; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Purchase
shares</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--StockRepurchasedDuringPeriodShares_pip0_c20221001__20230930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_zPFQuZyDqIK6" title="Purchase shares, shares" style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockRepurchasedDuringPeriodShares" contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">3,275,000</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockRepurchasedDuringPeriodValue" contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">3</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockRepurchasedDuringPeriodValue" contextRef="From2022-10-012023-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">27,872</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0436">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockRepurchasedDuringPeriodValue" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">27,875</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_405_ecustom--CommitmentShares_zFhDCFbsH4U5" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 20pt; font-family: Arial, Helvetica, Sans-Serif; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Commitment
shares</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_ecustom--CommitmentSharesShares_pip0_c20221001__20230930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_z2WfPEWk7029" title="Commitment shares, shares" style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:CommitmentSharesShares" contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">13,943</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0441">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0442">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0443">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0444">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_405_ecustom--SharesIssuedPursuantToExerciseOfStockOptions_zq7NkBBIBhz9" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Shares
issued pursuant to exercise of stock options</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98F_ecustom--SharesIssuedPursuantToExerciseOfStockOptionsShares_pip0_c20221001__20230930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_znZndjRgqq7d" title="Shares issued pursuant to exercise of stock options, shares" style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToExerciseOfStockOptionsShares" contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">759,753</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToExerciseOfStockOptions" contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToExerciseOfStockOptions" contextRef="From2022-10-012023-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,775</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0450">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:SharesIssuedPursuantToExerciseOfStockOptions" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,776</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_404_eus-gaap--AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_zMF0IYdYXpok" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Share
based compensation</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0455">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" contextRef="From2022-10-012023-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">16,370</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0457">&#8212;</span></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">16,370</ix:nonFraction></span></td>
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40A_eus-gaap--NetIncomeLoss_zLvXxVY5Agv8" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net
loss</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0460">&#8212;</span></span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0461">&#8212;</span></span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2022-10-012023-09-30_us-gaap_RetainedEarningsMember" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">47,505</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; font-family: Arial, Helvetica, Sans-Serif; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:NetIncomeLoss" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">47,505</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; font-family: Arial, Helvetica, Sans-Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_438_c20221001__20230930_eus-gaap--StockholdersEquity_iE_zNh4VhTRpiH7" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 2.5pt 10pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Balance,
September 30, 2023</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_981_eus-gaap--SharesOutstanding_iE_pip0_c20221001__20230930__us-gaap--StatementEquityComponentsAxis__us-gaap--CommonStockMember_zhIx3HRPcGe" title="Balance at ending, shares" style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:SharesOutstanding" contextRef="AsOf2023-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">82,066,511</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2023-09-30_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">82</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2023-09-30_us-gaap_AdditionalPaidInCapitalMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">434,839</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2023-09-30_us-gaap_RetainedEarningsMember" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">293,069</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:StockholdersEquity" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">141,852</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



<p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">See
Accompanying Notes to Consolidated Financial Statements</span></p>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b></b></span></p>

<!-- Field: Page; Sequence: 75; Value: 1 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->8<!-- Field: /Sequence --></p></div>
    <div style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: left"></p>

<p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Anavex
Life Sciences Corp.</span></p>

<p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Notes
to the Consolidated Financial Statements</span></p>

<p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30, 2023 &#8211; Page 9</span></p>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock"><p id="xdx_80E_eus-gaap--OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_zzwO6whBvBu3" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
1 &#9;<span id="xdx_827_zzKl0Cvv1eXc">Business Description and Basis of Presentation</span> </b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Business</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Anavex
Life Sciences Corp. (&#8220;Anavex&#8221; or the &#8220;Company&#8221;) is a clinical stage biopharmaceutical company engaged in the
development of differentiated therapeutics by applying precision medicine to central nervous system (&#8220;CNS&#8221;) diseases with
high unmet need. Anavex analyzes genomic data from clinical trials to identify biomarkers, which are used in the analysis of its clinical
trials for the treatment of neurodegenerative and neurodevelopmental diseases.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company&#8217;s lead compound ANAVEX<sup>&#174;</sup>2-73 (blarcamesine) is being developed to treat Alzheimer&#8217;s disease, Parkinson&#8217;s
disease and potentially other central nervous system diseases, including rare diseases, such as Rett syndrome, a rare severe neurological
monogenic disorder caused by mutations in the X-linked gene, methyl-CpG-binding protein 2 (&#8220;MECP2&#8221;).</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Basis
of Presentation </i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">These
consolidated financial statements have been prepared pursuant to the rules and regulations of the Securities and Exchange Commission
(&#8220;SEC&#8221;) and the instructions to Form 10-K and have been prepared under the accounting principles generally accepted in the
United States of America (&#8220;U.S. GAAP&#8221;).</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Liquidity</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">All
of the Company&#8217;s potential drug compounds are in the clinical development stage and the Company cannot be certain that its research
and development efforts will be successful or, if successful, that its potential drug compounds will ever be approved for sales to pharmaceutical
companies or generate commercial revenues. To date, we have not generated any revenues from our operations. The Company expects the business
to continue to experience negative cash flows from operations for the foreseeable future and cannot predict when, if ever, our business
might become profitable.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Management
believes that the current working capital position will be sufficient to meet the Company&#8217;s working capital requirements beyond
the next 12 months after the date that these consolidated financial statements are issued. The process of drug development can be costly,
and the timing and outcomes of clinical trials are uncertain.&#160;The assumptions upon which the Company has based its estimates are
routinely evaluated and may be subject to change.&#160;The actual amount of the Company&#8217;s expenditures will vary depending upon
a number of factors including but not limited to the design, timing and duration of future clinical trials, the progress of the Company&#8217;s
research and development programs and the level of financial resources available. The Company has the ability to adjust its operating
plan spending levels based on the timing of future clinical trials.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Other
than our rights related to the Purchase Agreement (as defined below in Note 5), there can be no assurance that additional financing will
be available to us when needed or, if available, that it can be obtained on commercially reasonable terms. If the Company is not able
to obtain the additional financing on a timely basis, if and when it is needed, it will be forced to delay or scale down some or all
of its research and development activities.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:SignificantAccountingPoliciesTextBlock"><p id="xdx_809_eus-gaap--SignificantAccountingPoliciesTextBlock_zhJnQIuZqXN" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
2&#9;<span id="xdx_825_z0b09WgWKbRj">Summary of Significant Accounting Policies</span> </b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:UseOfEstimates"><p id="xdx_848_eus-gaap--UseOfEstimates_z6qiTKflTLI2" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86B_zdIdNWMOYl8g">Use
of Estimates</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
preparation of financial statements in accordance with U.S. GAAP requires management to make estimates and assumptions that affect the
reported amounts of assets and liabilities at the date of the financial statements and the reported amounts of revenue and expenses in
the reporting period. The Company regularly evaluates estimates and assumptions related to accounting for research and development costs,
incentive income receivable, valuation and recoverability of deferred tax assets, stock based compensation, and loss contingencies. The
Company bases its estimates and assumptions on current facts, historical experience, and various other factors that it believes to be
reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and
liabilities and the accrual of costs and expenses that are not readily apparent from other sources. The actual results experienced by
the Company may differ materially and adversely from the Company&#8217;s estimates. To the extent there are material differences between
the estimates and the actual results, future results of operations will be affected.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<ix:exclude><p id="xdx_236_z1dHhz5k4jb3" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p></ix:exclude>

<ix:exclude><!-- Field: Page; Sequence: 76; Value: 1 -->
    <div id="xdx_232_zhsAfYqnCyyk" style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->9<!-- Field: /Sequence --></p></div>
    <div id="xdx_232_zuYXE60v0EN5" style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page --></ix:exclude>

<ix:exclude><p id="xdx_238_zd5WgemRNmNg" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p></ix:exclude>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p><ix:exclude><p id="xdx_230_zgiYmdYgf8H4" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Anavex
Life Sciences Corp.</span></p></ix:exclude>

<ix:exclude><p id="xdx_239_zwFyKeWgokVa" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Notes
to the Consolidated Financial Statements</span></p></ix:exclude>

<ix:exclude><p id="xdx_236_zHWhd6WWOGGf" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30, 2023 &#8211; Page 10</span></p></ix:exclude>

<ix:exclude><p id="xdx_238_zD5YyXCgfsp7" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0">&#160;</p></ix:exclude>


</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:ConsolidationPolicyTextBlock"><p id="xdx_84A_eus-gaap--ConsolidationPolicyTextBlock_z2ffcVZrWlFa" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_867_zBDDP2KxbUlg">Principles
of Consolidation</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">These
consolidated financial statements include the accounts of Anavex Life Sciences Corp. and its wholly-owned subsidiaries, Anavex Australia
Pty Limited (&#8220;Anavex Australia&#8221;), a company incorporated under the laws of Australia, Anavex Germany GmbH, a company incorporated
under the laws of Germany, and Anavex Canada Ltd., a company incorporated under the laws of the Province of Ontario, Canada. All inter-company
transactions and balances have been eliminated.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:CashAndCashEquivalentsPolicyTextBlock"><p id="xdx_842_eus-gaap--CashAndCashEquivalentsPolicyTextBlock_zD2psO58wgqi" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_860_zXnZYnJ3AxH9">Cash
and equivalents</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company considers only those investments which are highly liquid, readily convertible to cash and that mature within three months from
the date of purchase to be cash equivalents.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">Highly
liquid investments that are considered cash equivalents include money market&#160;accounts, money market&#160;funds&#160;and&#160;certificates
of deposit. The carrying value of cash equivalents approximates fair value due to the short-term maturity of these securities. The Company&#8217;s
investment policy allows for investments in domestic money market certificates, certificates of deposit, money market funds, bonds or
commercial papers, and establishes diversification and credit quality requirements and limits investments by maturity and issuer. The
Company currently maintains its investments at one large well known financial institution.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">The
Company maintains its cash in bank deposit accounts which, at times, may exceed federally insured limits. Accounts are guaranteed by
the Federal Deposit Insurance Corporation (FDIC) up to $<span id="xdx_90E_eus-gaap--CashFDICInsuredAmount_iI_c20230930_zOPrmEbs29Na" title="Federal deposit insurance corporation"><ix:nonFraction name="us-gaap:CashFDICInsuredAmount" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="0" unitRef="USD">250,000</ix:nonFraction></span> under current regulations. At September 30, 2023 and 2022, substantially
all of the Company&#8217;s cash balances were in excess of these federally insured limits. The Company mitigates this risk by maintaining
the majority of its cash balances in a large well-known financial institution. The Company has not experienced any losses in such accounts.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:ResearchAndDevelopmentExpensePolicy"><p id="xdx_849_eus-gaap--ResearchAndDevelopmentExpensePolicy_znu0D1C47Tij" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_869_zOUCigTgWOAl">Research
and Development Expenses</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development costs are expensed as incurred. These expenses are comprised of the costs of the Company&#8217;s proprietary research
and development efforts, including preclinical studies, clinical trials, manufacturing costs, employee salaries and benefits and stock-based
compensation expense, contract services including external research and development expenses incurred under arrangements with third parties
such as contract research organizations (&#8220;CROs&#8221;), facilities costs, overhead costs and other related expenses. Milestone
payments made by the Company to third parties are expensed when the specific milestone has been achieved. Manufacturing costs are expensed
as incurred in accordance with Accounting Standard Codification (&#8220;ASC&#8221;) 730, Research and Development, as these materials
have no alternative future use outside of their intended use.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Nonrefundable
advance payments for goods or services that will be used or rendered for future research and development activities are deferred and
amortized over the period that the goods are delivered, or the related services are performed, subject to an assessment of recoverability.
The Company makes estimates of costs incurred in relation to external CROs, and clinical site costs. When evaluating the adequacy of
the accrued liabilities, the Company analyzes progress of the trials and studies including the phase or completion of events, invoices
received and contracted costs. Judgments and estimates are made in determining the accrued balances at the end of any reporting period.
Actual results could differ from the Company&#8217;s estimates. The Company&#8217;s historical accrual estimates have not been materially
different from actual costs.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<ix:exclude><p id="xdx_230_zjpM1gQ9CnKb" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p></ix:exclude>

<ix:exclude><!-- Field: Page; Sequence: 77; Value: 1 -->
    <div id="xdx_234_zc5laTVNqT4k" style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->10<!-- Field: /Sequence --></p></div>
    <div id="xdx_23A_zZsgzYD0rsu6" style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page --></ix:exclude>

<ix:exclude><p id="xdx_23E_zdFzkyXsVUqg" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p></ix:exclude>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p><ix:exclude><p id="xdx_23A_zVgUJintTfE4" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Anavex
Life Sciences Corp.</span></p></ix:exclude>

<ix:exclude><p id="xdx_237_zwhyuntomVfh" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Notes
to the Consolidated Financial Statements</span></p></ix:exclude>

<ix:exclude><p id="xdx_233_zoCmP1UdRvEk" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30, 2023 &#8211; Page 11</span></p></ix:exclude>

<ix:exclude><p id="xdx_231_z3ToMpygO5X9" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0">&#160;</p></ix:exclude>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">In
addition, the Company incurs expenses in respect of intellectual property costs relating to patents and trademarks. The probability of
success and length of time to develop commercial applications of the drugs subject to the underlying patent and trademark costs is difficult
to determine and numerous risks and uncertainties exist with respect to the timely completion of the development projects. There is no
assurance the drugs subject to the underlying patents and trademarks will ever be successfully commercialized.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Due
to these risks and uncertainties, the patent and trademark costs do not meet the definition of an asset and thus are expensed as incurred
within general and administrative expenses.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:RevenueRecognitionIncentives"><p id="xdx_84A_eus-gaap--RevenueRecognitionIncentives_zXLfXylE6t0j" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86F_zOf8tSfJTM19">Research
and Development Incentive Income</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company is eligible to obtain certain research and development tax credits, including, through its wholly owned subsidiary Anavex Australia,
the Australian research and development tax incentive credit (the &#8220;Australia R&amp;D credit&#8221;) through a program administered
through the Australian Tax Office (the &#8220;ATO&#8221;) and AusIndustry, a division of the Australian Government&#8217;s Department
of Industry, Innovation and Science (&#8220;AusIndustry&#8221;). The Australia R&amp;D credit program provides for a cash refund based
on a percentage of eligible research and development activities undertaken in Australia by Anavex Australia. Anavex Australia is also
eligible under the Australia R&amp;D credit program to receive the cash refund for certain research and development expenses incurred
by Anavex Australia outside of Australia, to the extent such expenses are pre-approved by AusIndustry pursuant to an advanced overseas
finding application.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Australia R&amp;D credit program is available to eligible companies with an annual aggregate revenue of less than $20.0 million Australian
during the reimbursable period at a rate of 18.5% above the claimant&#8217;s company tax rate in Australia.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
tax incentives are available on the basis of specific criteria with which the Company must comply. Although the tax incentive may be
administered through the local tax authority, the Company has accounted for the incentives outside of the scope of ASC Topic 740, Income
Taxes (&#8220;ASC 740&#8221;), since the incentives are not linked to the Company&#8217;s taxable income and can be realized regardless
of whether the Company has generated taxable income in the respective jurisdictions.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">With
respect to the Australia R&amp;D credit, as there is no authoritative guidance under GAAP for accounting for grants to for-profit business
entities, the Company accounts for the grant by analogy to IAS20 Accounting for Government Grants and Disclosure of Government Assistance
(&#8220;IAS 20&#8221;). The Company recognizes the Research and Development Incentive income as it incurs costs eligible for reimbursement
under the Australia R&amp;D credit program when it is reasonably assured that the cash incentive will be received, as evidenced through
enrollment in the program and when the applicable conditions under the program have been met. The Company accrues for the amount of cash
refund it expects to receive in relation to research and development expenses outside of Australia only to the extent it has received
advanced approval from AusIndustry, pursuant to an approved advanced overseas finding application.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">In
addition, Anavex Australia and Anavex Canada incur Goods and Services Tax (GST) on certain services provided by local vendors. As a domestic
entity in those jurisdictions, Anavex Australia and Anavex Canada are entitled to a refund of the GST paid. Similarly, Anavex Germany
incurs Value Added Tax (VAT) on certain services provided by local vendors, to which it is entitled to a refund of such VAT paid. The
Company&#8217;s estimate of the amount of cash refund it expects to receive related to GST and VAT incurred is included in Incentive
and tax receivables in the accompanying consolidated balance sheets.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="avxl:LicenseFeesPolicyTextBlock"><p id="xdx_843_ecustom--LicenseFeesPolicyTextBlock_zbyGkTcneVC" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_867_zUYRjRzpeyi4">License
Fees</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">The
Company expenses amounts paid to acquire licenses associated with products under development when the ultimate recovery of the amounts
paid is uncertain and the technology has no alternative future use when acquired. Acquisitions of technology licenses are charged to
expense or capitalized based on management&#8217;s assessment regarding the ultimate recoverability of the amounts paid and the potential
for alternative future use. The Company has determined that the technological feasibility for its product candidates is reached when
the requisite regulatory approvals are obtained to make the product available for sale.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<ix:exclude><p id="xdx_231_zkFhLPeLban" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif"></span></p></ix:exclude>

<ix:exclude><!-- Field: Page; Sequence: 78; Value: 1 -->
    <div id="xdx_238_zBW3ENPNZnIc" style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->11<!-- Field: /Sequence --></p></div>
    <div id="xdx_230_z9u3n5lc6N42" style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page --></ix:exclude>

<ix:exclude><p id="xdx_23D_zRegQXLQ0lUd" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p></ix:exclude>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"></p><ix:exclude><p id="xdx_237_zu1yu6IASG7j" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Anavex
Life Sciences Corp.</span></p></ix:exclude>

<ix:exclude><p id="xdx_23F_z5ibDUcghNkj" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Notes
to the Consolidated Financial Statements</span></p></ix:exclude>

<ix:exclude><p id="xdx_232_z7ZZmOGiLQod" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30, 2023 &#8211; Page 12</span></p></ix:exclude>

<ix:exclude><p id="xdx_239_ziB0GDKvmkJ8" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0">&#160;</p></ix:exclude>


</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:EarningsPerSharePolicyTextBlock"><p id="xdx_84A_eus-gaap--EarningsPerSharePolicyTextBlock_zCP0CRX2uWKf" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_869_z0KRlrCTQKH4">Basic
and Diluted Loss per Share</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Basic
income/(loss) per common share is computed by dividing net income/(loss) available to common stockholders by the weighted average number
of common shares outstanding during the period. Diluted income/(loss) per common share is computed by dividing net income/(loss) available
to common stockholders by the sum of (1) the weighted-average number of common shares outstanding during the period, (2) the dilutive
effect of the assumed exercise of options and warrants using the treasury stock method and (3) the dilutive effect of other potentially
dilutive securities. For purposes of the diluted net loss per share calculation, options and warrants are potentially dilutive securities
and are excluded from the calculation of diluted net loss per share because their effect would be anti-dilutive.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">As
of September 30, 2023, diluted loss per share excludes <span id="xdx_904_eus-gaap--AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c20221001__20230930_zzmQzTvS2P9b" title="Loss per share for potentially dilutive common shares"><ix:nonFraction name="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="INF" unitRef="Shares">14,271,780</ix:nonFraction></span> potentially dilutive common shares (2022 &#8211;<span id="xdx_900_eus-gaap--AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c20211001__20220930_zvFJQdLARASf" title="Loss per share for potentially dilutive common shares"><ix:nonFraction name="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="INF" unitRef="Shares">13,329,616</ix:nonFraction></span>; 2021 &#8211;
<span id="xdx_905_eus-gaap--AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c20201001__20210930_zhPkKNvGs2j" title="Loss per share for potentially dilutive common shares"><ix:nonFraction name="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="INF" unitRef="Shares">11,540,903</ix:nonFraction></span>) related to outstanding options and warrants, as their effect was anti-dilutive.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:FairValueOfFinancialInstrumentsPolicy"><p id="xdx_84C_eus-gaap--FairValueOfFinancialInstrumentsPolicy_zsg1xhuLguk9" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_861_z1ynJO0M7YLg">Financial
Instruments</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
book value of the Company&#8217;s financial instruments, consisting of cash and equivalents, incentive and tax receivables, accounts
payable and accrued liabilities approximate their fair value due to the short-term maturity of such instruments. Unless otherwise noted,
it is management&#8217;s opinion that the Company is not exposed to significant interest, currency or credit risks arising from these
financial instruments.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock"><p id="xdx_845_eus-gaap--ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_zzpRJBWkzLGg" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_863_zFNDDXLlBLU7">Foreign
Currency Translation</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
functional currency of the Company is the US dollar. Monetary items denominated in a foreign currency are translated into US dollars
at exchange rates prevailing at the balance sheet date and non-monetary items are translated at exchange rates prevailing when the assets
were acquired, or obligations incurred. Foreign currency denominated expense items are translated at exchange rates prevailing on the
transaction date. Unrealized gains or losses arising from the translations are credited or charged to income in the period in which they
occur.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company has determined that the functional currency of Anavex Australia Pty Limited, Anavex Germany GmbH, and Anavex Canada Ltd. is also
the US dollar.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:SegmentReportingPolicyPolicyTextBlock"><p id="xdx_847_eus-gaap--SegmentReportingPolicyPolicyTextBlock_zmPlKfcJlDNj" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86A_zRFjDP3i0Wx9">Segment
and Geographic Reporting</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Operating
segments are defined as components of an enterprise for which separate discrete information is available for evaluation by the chief
operating decision maker or decision-making group, in deciding how to allocate resources and in assessing performance. The Company views
its operations and manages its business as one operating segment, which is the business of developing novel therapies for the management
of CNS diseases.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="avxl:GrantIncomePolicyTextBlock"><p id="xdx_84C_ecustom--GrantIncomePolicyTextBlock_zRVfCktQIAsj" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_865_z4nGz9Qg9Cfe">Grant
Income</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Grant
income is recognized at the fair value of the grant when it is received, and all substantive conditions have been satisfied. Grants received
from government and other agencies in advance of the specific research and development costs to which they relate are deferred and recognized
in the consolidated statements of operations in the period they are earned, typically when the related research and development costs
are incurred.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<ix:exclude><p id="xdx_232_z1MnSWhXYPD8" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p></ix:exclude>

<ix:exclude><!-- Field: Page; Sequence: 79; Value: 1 -->
    <div id="xdx_237_zIk5D8fiPqEh" style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->12<!-- Field: /Sequence --></p></div>
    <div id="xdx_235_zlV4wGcMtM86" style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page --></ix:exclude>

<ix:exclude><p id="xdx_232_zL7l1Oobsdee" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p></ix:exclude>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p><ix:exclude><p id="xdx_234_zUABeoJJXmyi" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Anavex
Life Sciences Corp.</span></p></ix:exclude>

<ix:exclude><p id="xdx_23C_zdPSQqam8yK6" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Notes
to the Consolidated Financial Statements</span></p></ix:exclude>

<ix:exclude><p id="xdx_236_zfEtEzK84Ymh" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30, 2023 &#8211; Page 13</span></p></ix:exclude>

<ix:exclude><p id="xdx_234_zVdXd3ASUQz7" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0">&#160;</p></ix:exclude>


</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:IncomeTaxPolicyTextBlock"><p id="xdx_840_eus-gaap--IncomeTaxPolicyTextBlock_zZy051LYIQye" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86B_zFTWQtNxH2pj">Income
Taxes</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company follows the provisions of ASC 740, which requires the asset and liability method of accounting for income taxes. Under the asset
and liability method, deferred tax assets and liabilities are recognized for the future tax consequences attributable to temporary differences
between the financial statements carrying amounts of existing assets and liabilities and their respective tax bases. Deferred tax assets
and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences
are expected to be recovered or settled.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company follows the provisions of ASC 740 regarding accounting for uncertainty in income taxes. The Company initially recognizes tax
positions in the financial statements when it is more likely than not the position will be sustained upon examination by the tax authorities.
Such tax positions are initially and subsequently measured as the largest amount of tax benefit that is greater than 50% likely of being
realized upon ultimate settlement with the tax authority assuming full knowledge of the position and all relevant facts. Application
requires numerous estimates based on available information. The Company considers many factors when evaluating and estimating its tax
positions and tax benefits, and its recognized tax positions and tax benefits may not accurately anticipate actual outcomes. As additional
information is obtained, there may be a need to periodically adjust the recognized tax positions and tax benefits. These periodic adjustments
may have a material impact on the consolidated statements of operations.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company recognizes interest and penalties related to current income tax expense on the interest income, net line, in the accompanying
consolidated statements of operations. Accrued interest and penalties, if any, are included in accrued liabilities on the consolidated
balance sheets.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:ShareBasedCompensationForfeituresPolicyTextBlock"><p id="xdx_841_eus-gaap--ShareBasedCompensationForfeituresPolicyTextBlock_zTxkzG9e8Qce" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86C_zro2ToXrby56">Stock-based
Compensation</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company accounts for all stock-based payments and awards under the fair value method.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
fair value of all share purchase options and warrants are expensed over their contractual vesting period, or over the expected performance
period for only the portion of awards expected to vest, in the case of milestone-based vesting, with a corresponding increase to additional
paid-in capital.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Compensation
costs for stock-based payments with graded vesting are recognized on a straight-line basis. Stock based compensation expense is adjusted
for actual forfeitures of unvested awards as they occur.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company has granted share purchase option awards that vest upon achievement of certain performance criteria, or milestone-based awards.
The Company estimates an implicit service period for achieving performance criteria for each award and recognizes the resulting fair
value as expense over the implicit service period when it concludes that achieving the performance criteria is probable. The Company
periodically reviews and updates as appropriate its estimates of implicit service periods and conclusions on achieving the performance
criteria. Performance awards vest upon achievement of the performance criteria.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company uses the Black-Scholes option valuation model to calculate the fair value of share purchase options and warrants at the date
of the grant. This model requires the input of subjective assumptions, including the expected price volatility and expected life of each&#160;award.
The Company uses the U.S. Treasury daily treasury yield curve rates for the expected term of the option as the risk-free rate. The expected
term represents the period that options granted are expected to be outstanding using the simplified method. The Company&#8217;s historical
share option exercise experience does not provide sufficient basis for estimating the expected term. Expected volatility is based on
the average of the daily share price changes over the expected term. The Company does not estimate forfeitures and elects to record actual
forfeitures as they occur. The Company has not paid any dividends on its common stock historically, therefore no assumption of dividend
payments is made in the model. These assumptions consist of estimates of future market conditions, which are inherently uncertain, and
therefore, are subject to management&#8217;s judgment. Changes in these assumptions can materially affect the fair value estimates.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<ix:exclude><p id="xdx_238_z9EwukWPuDik" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p></ix:exclude>

<ix:exclude><!-- Field: Page; Sequence: 80; Value: 1 -->
    <div id="xdx_238_zBdgem5GBt89" style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->13<!-- Field: /Sequence --></p></div>
    <div id="xdx_239_z9n6kRGN0BF1" style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page --></ix:exclude>

<ix:exclude><p id="xdx_230_z79Un5hRR1A9" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p></ix:exclude>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p><ix:exclude><p id="xdx_230_zmlOe3zk1U1i" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Anavex
Life Sciences Corp.</span></p></ix:exclude>

<ix:exclude><p id="xdx_23C_ziGwgFQXWaBi" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Notes
to the Consolidated Financial Statements</span></p></ix:exclude>

<ix:exclude><p id="xdx_234_zZNJTBwKeKc7" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30, 2023 &#8211; Page 14</span></p></ix:exclude>

<ix:exclude><p id="xdx_236_ztj0JBzbSc1f" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p></ix:exclude>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
purchase price of options or warrants may be paid in cash or, if approved by the Company&#8217;s compensation committee (or in the case
of warrants by the Board of Directors) in advance, &#8220;net settled&#8221; in shares of the Company&#8217;s common stock. In a net
settlement of an option or warrant, the Company does not receive payment of the exercise price from the holder but reduces the number
of shares of common stock issued upon the exercise of the stock option or warrant by the smallest number of whole shares that have an
aggregate fair market value equal to or over the aggregate exercise price for the option shares covered by the option or warrant exercised.
Shares issued pursuant to the exercise of options and warrants are issued from the Company&#8217;s treasury.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:FairValueMeasurementPolicyPolicyTextBlock"><p id="xdx_84F_eus-gaap--FairValueMeasurementPolicyPolicyTextBlock_zJIfEwJU8NVi" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86F_z75dfpAXfjJj">Fair
Value Measurements</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Fair
value is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal
or most advantageous market for the asset or liability in an orderly transaction between market participants at the measurement date.
Assets and liabilities that are measured at fair value are reported using a three-level fair value hierarchy that prioritizes the inputs
used to measure fair value. This hierarchy maximizes the use of observable inputs and minimizes the use of unobservable inputs. The three
levels of inputs used to measure fair value are as follows:</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Level
1 - &#9;quoted prices (unadjusted) in active markets for identical assets or liabilities that the Company has the ability to access at
the measurement date;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Level
2 - observable inputs other than Level 1, quoted prices for similar assets or liabilities in active &#9;&#9;markets, quoted prices for
identical or similar assets and liabilities in markets that are not active, and model-derived prices whose inputs are observable or whose
significant value drivers are observable; and</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Level
3 - &#9;assets and liabilities whose significant value drivers are unobservable by little or no market activity and that are significant
to the fair value of the assets or liabilities.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">At
September 30, 2023 and 2022, the Company did not have any Level 2 or Level 3 assets or liabilities.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:NewAccountingPronouncementsPolicyPolicyTextBlock"><p id="xdx_84A_eus-gaap--NewAccountingPronouncementsPolicyPolicyTextBlock_zLldraoEwC7c" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_864_z3SKDNiOVEng">Recently
Adopted Accounting Pronouncements</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Effective
October 1, 2021, the Company adopted Accounting Standards Update (&#8220;ASU&#8221;) 2019-12, &#8220;Simplifying the Accounting for Income
Taxes (ASC 740)&#8221;, which is intended to simplify various aspects related to accounting for income taxes by removing certain exceptions
to the general principles in Topic 740 and clarifying and amending existing guidance to improve consistent application. There was no
material impact on the Company&#8217;s operations, financial condition, or cash flows.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
October 1, 2022, the Company adopted ASU 2021-10, Annual Disclosure Requirements for Business Entities Receiving Government Assistance
(Topic 832) &#8211; Disclosures by Business Entities about Government Assistance, which requires business entities to disclose information
about transactions with a government that are accounted for by applying a grant or contribution model by analogy. For transactions within
scope, the new standard requires the disclosure of information about the nature of the transaction, including significant terms and conditions,
as well as the amounts and specific financial statement line items affected by the transaction. The disclosure of the Company&#8217;s
research and development tax incentive income and receivable is detailed in Note 4.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<ix:exclude><p id="xdx_232_z6rJs7VJ7FLe" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p></ix:exclude>

<ix:exclude><!-- Field: Page; Sequence: 81; Value: 1 -->
    <div id="xdx_23A_zwweaUqeuUrh" style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->14<!-- Field: /Sequence --></p></div>
    <div id="xdx_232_zfQE2SunnTxe" style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page --></ix:exclude>

<ix:exclude><p id="xdx_23B_z8OS9ba2PeR8" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p></ix:exclude>

<ix:exclude><p id="xdx_23B_zWRbrNnNaxg4" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Anavex
Life Sciences Corp.</span></p></ix:exclude>

<ix:exclude><p id="xdx_23F_zLNKvSgqrlG2" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Notes
to the Consolidated Financial Statements</span></p></ix:exclude>

<ix:exclude><p id="xdx_231_zVPPgLz0wIHk" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30, 2023 &#8211; Page 15</span></p></ix:exclude>

<ix:exclude><p id="xdx_235_z3VmOlSp9HR7" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0">&#160;</p></ix:exclude>


</ix:nonNumeric></ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="avxl:AccuredLiabilitiesTextBlock"><p id="xdx_800_ecustom--AccuredLiabilitiesTextBlock_zWiWbayK1Fog" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
3&#9;<span id="xdx_82E_zhZbrFyFkNS2">Accrued Liabilities</span> </b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
principal components of accrued liabilities consist of (in thousands):</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>

<ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:ScheduleOfAccruedLiabilitiesTableTextBlock"><table cellpadding="0" cellspacing="0" id="xdx_88F_eus-gaap--ScheduleOfAccruedLiabilitiesTableTextBlock_pn3n3_zw7Q0sR5wox1" summary="xdx: Disclosure - Accrued Liabilities (Details)" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span id="xdx_8B9_z9D2IZIcaaxc" style="display: none">Schedule of principal components of accrued liabilities</span></td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td id="xdx_49F_20230930_zOblcHItXB76" style="text-align: center">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td id="xdx_496_20220930_zC7voMSPrPQc" style="text-align: center">&#160;</td>
<td style="text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="7" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30,</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td></tr>
<tr id="xdx_40F_ecustom--AccruedClinicalSiteAndPatientVisitsCosts_iI_maALCz5rZ_zzgKyxye7SBb" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 56%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accrued
clinical site and patient visits costs</span></td>
<td style="width: 8%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 12%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:AccruedClinicalSiteAndPatientVisitsCosts" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">2,006</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 8%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 12%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:AccruedClinicalSiteAndPatientVisitsCosts" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">2,031</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_403_eus-gaap--AccruedBonusesCurrent_iI_maALCz5rZ_zPPgeMs8YLF3" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accrued
compensation and benefits</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AccruedBonusesCurrent" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,360</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AccruedBonusesCurrent" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,298</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40A_ecustom--FixedContractAccruals_iI_maALCz5rZ_zGGMM1w3vkW4" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Fixed
contract accruals</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:FixedContractAccruals" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">38</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:FixedContractAccruals" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">417</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_405_ecustom--MilestoneBasedContractAccruals_iI_maALCz5rZ_zewnh5C4LrUk" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Milestone
based contract accruals</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:MilestoneBasedContractAccruals" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,267</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:MilestoneBasedContractAccruals" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">137</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40B_eus-gaap--OtherAccruedLiabilitiesCurrent_iI_maALCz5rZ_z65jJeLLNDBi" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">All
other accrued liabilities</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:OtherAccruedLiabilitiesCurrent" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">2,624</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:OtherAccruedLiabilitiesCurrent" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">2,062</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_400_eus-gaap--AccruedLiabilitiesCurrent_iTI_mtALCz5rZ_zK68g3Y0HK82" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 2.5pt 10pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total
accrued liabilities</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AccruedLiabilitiesCurrent" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">7,295</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:AccruedLiabilitiesCurrent" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">5,945</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table></ix:nonNumeric>



<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="avxl:OtherIncomeDisclosureTextBlock"><p id="xdx_804_ecustom--OtherIncomeDisclosureTextBlock_z7ED0CC1PYJ4" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
4&#9;<span id="xdx_820_zezQfDrLEqdi">Other Income</span></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Grant
income</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">During
the year ended September 30, 2023, the Company received $<span id="xdx_906_ecustom--GrantIncome_pn5n6_c20221001__20230930_zIuHWYwmVaId" title="Grant income"><ix:nonFraction name="avxl:GrantIncome" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">0.5</ix:nonFraction></span> million (2022: $<span id="xdx_903_ecustom--GrantIncome_c20211001__20220930_zd1fw8vKH0Bj" title="Grant income"><ix:nonFraction name="avxl:GrantIncome" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="0" unitRef="USD">0</ix:nonFraction></span> 2021: $<span id="xdx_905_ecustom--GrantIncome_pn5n6_c20201001__20210930_zKaZ0kl3IiR7" title="Grant income"><ix:nonFraction name="avxl:GrantIncome" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">0.5</ix:nonFraction></span> million) of a $<span id="xdx_903_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20201001__20210930__us-gaap--RelatedPartyTransactionsByRelatedPartyAxis__custom--MichaelJFoxFoundationMember_zUiITfrFOqaa" title="Research and development incentive income"><ix:nonFraction name="us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned" contextRef="From2020-10-012021-09-30_custom_MichaelJFoxFoundationMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">1</ix:nonFraction></span>.0 million research grant awarded
during the year ended September 30, 2021, by the Michael J. Fox Foundation for Parkinson&#8217;s Research. The grant will be used to
fund a clinical trial of the Company&#8217;s lead compound, ANAVEX<sup>&#174;</sup>2-73 (blarcamesine) related to Parkinson&#8217;s disease.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
grant income was deferred when received and amortized to other income as the related research and development expenditures are incurred.
During the year ended September 30, 2023, the Company recognized $<span id="xdx_90D_ecustom--NonOperatingIncomeFromGrant_c20221001__20230930_zlOdEtzkeJL3" title="Non operating income from grant"><ix:nonFraction name="avxl:NonOperatingIncomeFromGrant" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="0" unitRef="USD">25,000</ix:nonFraction></span> (2022: $<span id="xdx_903_ecustom--NonOperatingIncomeFromGrant_c20211001__20220930_zkvjDz7v4wHd" title="Non operating income from grant"><ix:nonFraction name="avxl:NonOperatingIncomeFromGrant" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="0" unitRef="USD">0</ix:nonFraction></span>; 2021: $<span id="xdx_900_ecustom--NonOperatingIncomeFromGrant_c20201001__20210930_z2o8qeI1rZo4" title="Non operating income from grant"><ix:nonFraction name="avxl:NonOperatingIncomeFromGrant" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="0" unitRef="USD">54,100</ix:nonFraction></span>) of this grant on its statements of
operations within grant income. At September 30, 2023 an amount of $<span id="xdx_906_ecustom--DeferredGrantIncome1_pn5n6_c20221001__20230930_zxwtGse5Gk57" title="Deferred grant income"><ix:nonFraction name="avxl:DeferredGrantIncome1" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">0.9</ix:nonFraction></span> million (2022: $<span id="xdx_90B_ecustom--DeferredGrantIncome1_pn5n6_c20211001__20220930_ztxPyoxVQksl" title="Deferred grant income"><ix:nonFraction name="avxl:DeferredGrantIncome1" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">0.4</ix:nonFraction></span> million) of this grant is recorded as deferred
grant income, representing the amount of this grant which has not yet been amortized to other income. The Company will recognize this
income on its statements of operations as the related expenditures are incurred to offset the income.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Research
and development incentive income</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development incentive income represents the income earned by Anavex Australia of the Australia R&amp;D credit. This cash incentive
is received by Anavex Australia, upon filing of a claim in connection with Anavex Australia&#8217;s annual income tax return.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">During
the year ended September 30, 2023, the Company recorded research and development incentive income of $<span id="xdx_900_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20221001__20230930_zID3NUwQhl64" title="Research and development incentive income"><ix:nonFraction name="us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">2.7</ix:nonFraction></span> million (AUD <span id="xdx_906_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20221001__20230930__srt--CurrencyAxis__currency--AUD_zU8tfJYJcOWc" title="Research and development incentive income"><ix:nonFraction name="us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned" contextRef="From2022-10-012023-09-30_currency_AUD" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">4.1</ix:nonFraction></span> million) (2022:
$<span id="xdx_900_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20211001__20220930_z9qs1g3PLpXc" title="Research and development incentive income"><ix:nonFraction name="us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">3.3</ix:nonFraction></span> million (AUD <span id="xdx_908_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20211001__20220930__srt--CurrencyAxis__currency--AUD_zXzB35mMhmpl" title="Research and development incentive income"><ix:nonFraction name="us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned" contextRef="From2021-10-012022-09-30_currency_AUD" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">4.5</ix:nonFraction></span> million); 2021: $<span id="xdx_90B_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20201001__20210930_zl46LELTKP84" title="Research and development incentive income"><ix:nonFraction name="us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">4.5</ix:nonFraction></span> million (AUD <span id="xdx_90F_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20201001__20210930__srt--CurrencyAxis__currency--AUD_zJ25LJXGoyc5" title="Research and development incentive income"><ix:nonFraction name="us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned" contextRef="From2020-10-012021-09-30_currency_AUD" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">6.1</ix:nonFraction></span> million)) in respect of the Australia R&amp;D credit for eligible research
and development expenses incurred during the year. This amount is included within Other income (expense) on the consolidated statements
of operations.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">At
September 30, 2023, Incentive and tax receivables includes $<span id="xdx_904_eus-gaap--OtherReceivables_iI_pn5n6_c20230930_zzdtGDxecS6i" title="Incentive and tax receivables"><ix:nonFraction name="us-gaap:OtherReceivables" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">2.5</ix:nonFraction></span> million (AUD <span id="xdx_903_eus-gaap--OtherReceivables_iI_pn5n6_c20230930__srt--CurrencyAxis__currency--AUD_z33if1GWYJ43" title="Incentive and tax receivables"><ix:nonFraction name="us-gaap:OtherReceivables" contextRef="AsOf2023-09-30_currency_AUD" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">3.9</ix:nonFraction></span> million) (2022: $<span id="xdx_906_eus-gaap--OtherReceivables_iI_pn5n6_c20220930_zl6nET4zhSgf" title="Incentive and tax receivables"><ix:nonFraction name="us-gaap:OtherReceivables" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">2.9</ix:nonFraction></span> million (AUD <span id="xdx_908_eus-gaap--OtherReceivables_iI_pn5n6_c20220930__srt--CurrencyAxis__currency--AUD_z4Fmw8vKgvI2" title="Incentive and tax receivables"><ix:nonFraction name="us-gaap:OtherReceivables" contextRef="AsOf2022-09-30_currency_AUD" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">4.5</ix:nonFraction></span> million) relating
to Australia R&amp;D credits earned during the year that are expected to be reimbursed upon filing of the Company&#8217;s annual claim
under this program.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Australia R&amp;D credit program is a self-assess program whereby the Company must assess its eligibility each year to determine (i)
if the entity is eligible (ii) if the specific R&amp;D activities are eligible and (iii) if the individual R&amp;D expenditures have
nexus to such R&amp;D activities. The Company evaluates its eligibility under the tax incentive program as of each balance sheet date
based on the most current and relevant data available. Anavex Australia is able to continue to claim the R&amp;D tax incentive for as
long as it remains eligible and continues to incur eligible research and development expenditures.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<ix:exclude><p id="xdx_237_zizMG2tyYyI5" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p></ix:exclude>

<ix:exclude><!-- Field: Page; Sequence: 82; Value: 1 -->
    <div id="xdx_231_zbYjj8j8FmSd" style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->15<!-- Field: /Sequence --></p></div>
    <div id="xdx_23A_z87dhIVIUji9" style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page --></ix:exclude>

<ix:exclude><p id="xdx_23B_zirOOOLSxcTe" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p></ix:exclude>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"></p><ix:exclude><p id="xdx_230_zu7UMKaCcrwi" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Anavex
Life Sciences Corp.</span></p></ix:exclude>

<ix:exclude><p id="xdx_23F_zsEk8g1W71Hk" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Notes
to the Consolidated Financial Statements</span></p></ix:exclude>

<ix:exclude><p id="xdx_237_z6F0dh3x8pJ6" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30, 2023 &#8211; Page 16</span></p></ix:exclude>

<ix:exclude><p id="xdx_237_zP4TthmDj52l" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0">&#160;</p></ix:exclude>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Although
the Company believes that it has complied with all the relevant conditions of eligibility under the program for all periods claimed,
the ATO has the right to review the Company&#8217;s qualifying programs and related expenditures for a period of four years. If such
a review were to occur, the ATO may have different interpretations of certain eligibility requirements. If the ATO disagreed with the
Company&#8217;s assessments and any related subsequent appeals, it could require adjustment to and repayment of current or previous years&#8217;
claims already received. Additionally, if the Company was unable to demonstrate a reasonably arguable position taken on such claims,
the ATO could also assess penalties and interest on such adjustment.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Currently,
the Company&#8217;s tax incentive claims from 2019 to 2022 are open to potential review by the ATO. Additionally, the period open for
review is indefinite if the ATO suspects fraud. The Company has not provided any allowance for any such potential adjustments, should
they occur in the future.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="avxl:EquityOfferingTextBlock"><p id="xdx_804_ecustom--EquityOfferingTextBlock_zb4TDoN2phd4" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
5&#9;<span id="xdx_820_zyNNCA0EwmA4">Equity Offerings</span></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Common
Stock</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common
shares are voting and are entitled to dividends as declared at the discretion of the Board of Directors.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Preferred
Stock</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company&#8217;s Board of Directors&#160;(the &#8220;Board&#8221;)&#160;has the authority to issue preferred stock in one or more series
and to fix the rights, preferences, privileges, restrictions and the number of shares constituting any series or the designation of the
series.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Registered
Direct Offering</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
June 22, 2021, the Company and Deep Track Capital entered into a securities purchase agreement pursuant to which the Company sold to
Deep Track Capital an aggregate of <span id="xdx_90D_eus-gaap--SaleOfStockNumberOfSharesIssuedInTransaction_pip0_c20210621__20210622__us-gaap--TypeOfArrangementAxis__custom--SecuritiesPurchaseAgreementMember_zc6y134LHS88" title="Sale of stock, shares"><ix:nonFraction name="us-gaap:SaleOfStockNumberOfSharesIssuedInTransaction" contextRef="From2021-06-212021-06-22_custom_SecuritiesPurchaseAgreementMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">2,380,953</ix:nonFraction></span> shares of common stock at $<span id="xdx_902_eus-gaap--SaleOfStockPricePerShare_iI_pip0_c20210622__us-gaap--TypeOfArrangementAxis__custom--SecuritiesPurchaseAgreementMember_zW7JGKcfhi15" title="Sale of stock, per share"><ix:nonFraction name="us-gaap:SaleOfStockPricePerShare" contextRef="AsOf2021-06-22_custom_SecuritiesPurchaseAgreementMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">21</ix:nonFraction></span> per share in a registered direct offering, for gross proceeds
of $<span id="xdx_909_eus-gaap--SaleOfStockConsiderationReceivedOnTransaction_pn6n6_c20210621__20210622__us-gaap--TypeOfArrangementAxis__custom--SecuritiesPurchaseAgreementMember_zpiUI66Lxw1a" title="Gross proceeds from sale of stock"><ix:nonFraction name="us-gaap:SaleOfStockConsiderationReceivedOnTransaction" contextRef="From2021-06-212021-06-22_custom_SecuritiesPurchaseAgreementMember" format="ixt:numdotdecimal" decimals="-6" scale="6" unitRef="USD">50</ix:nonFraction></span> million. Net proceeds of the offering were $<span id="xdx_90E_eus-gaap--ProceedsFromIssuanceInitialPublicOffering_c20210621__20210622__us-gaap--TypeOfArrangementAxis__custom--SecuritiesPurchaseAgreementMember_zUSWYrXZ3X09" title="Proceed from offering"><ix:nonFraction name="us-gaap:ProceedsFromIssuanceInitialPublicOffering" contextRef="From2021-06-212021-06-22_custom_SecuritiesPurchaseAgreementMember" format="ixt:numdotdecimal" decimals="0" unitRef="USD">46,902,981</ix:nonFraction></span> after deducting offering fees and expenses.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Sales
Agreement</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company entered into a Controlled Equity Offering Sales Agreement on July 6, 2018, which was amended and restated on May 1, 2020 (the
&#8220;Sales Agreement&#8221;) with Cantor Fitzgerald&#160;&amp; Co. and SVB Leerink LLC (together the &#8220;Sales Agents&#8221;), pursuant
to which the Company may offer and sell shares of common stock registered under an effective registration statement from time to time
through the Sales Agents (the &#8220;Offering&#8221;).</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Upon
delivery of a placement notice based on the Company&#8217;s instructions and subject to the terms and conditions of the Sales Agreement,
the Sales Agents may sell the Shares by methods deemed to be an &#8220;at the market offering&#8221; offering, in negotiated transactions
at market prices prevailing at the time of sale or at prices related to such prevailing market prices, or by any other method permitted
by law, including negotiated transactions, subject to the prior written consent of the Company. The Company is not obligated to make
any sales of Shares under the Sales Agreement. The Company or Sales Agents may suspend or terminate the offering of Shares upon notice
to the other party, subject to certain conditions. The Sales Agents will act as agent on a commercially reasonable efforts basis consistent
with their normal trading and sales practices and applicable state and federal law, rules&#160;and regulations and the rules&#160;of
Nasdaq.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company has agreed to pay the Sales Agents commissions for their services of up to <span id="xdx_903_ecustom--PercentageOfGrossProceedsFromSales_pip0_dp_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zlabhXU0ZUv5" title="Percentage of gross proceeds from sales"><ix:nonFraction name="avxl:PercentageOfGrossProceedsFromSales" contextRef="From2022-10-012023-09-30_custom_EquityOfferingSalesAgreementMember" format="ixt:numdotdecimal" decimals="INF" scale="-2" unitRef="Pure">3.0</ix:nonFraction></span>% of the gross proceeds from the sale of the Shares
pursuant to the Sales Agreement. The Company also agreed to provide the Sales Agents with customary indemnification and contribution
rights. During the year ended September 30, 2023, <span id="xdx_90A_eus-gaap--SaleOfStockNumberOfSharesIssuedInTransaction_pip0_do_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zQ3IqyGRUkTa" title="Number of common stock sold, shares"><ix:nonFraction name="us-gaap:SaleOfStockNumberOfSharesIssuedInTransaction" contextRef="From2022-10-012023-09-30_custom_EquityOfferingSalesAgreementMember" format="ixt-sec:numwordsen" decimals="INF" scale="0" unitRef="Shares">no</ix:nonFraction></span> shares were sold pursuant to the Offering. During the year ended September 30, 2022,
<span id="xdx_906_eus-gaap--SaleOfStockNumberOfSharesIssuedInTransaction_pip0_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zjhhMExQvuvh" title="Number of common stock sold, shares"><ix:nonFraction name="us-gaap:SaleOfStockNumberOfSharesIssuedInTransaction" contextRef="From2021-10-012022-09-30_custom_EquityOfferingSalesAgreementMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">1,623,813</ix:nonFraction></span> shares were sold pursuant to the Offering for gross proceeds of $<span id="xdx_900_eus-gaap--SaleOfStockConsiderationReceivedPerTransaction_pn6n6_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zW5D1KhaZJV1" title="Number of common stock sold, value"><ix:nonFraction name="us-gaap:SaleOfStockConsiderationReceivedPerTransaction" contextRef="From2021-10-012022-09-30_custom_EquityOfferingSalesAgreementMember" format="ixt:numdotdecimal" decimals="-6" scale="6" unitRef="USD">21</ix:nonFraction></span>.0 million (net proceeds of $<span id="xdx_90A_eus-gaap--ProceedsFromIssuanceInitialPublicOffering_pn5n6_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zPbB3LyZ0Sqi" title="Net proceed"><ix:nonFraction name="us-gaap:ProceedsFromIssuanceInitialPublicOffering" contextRef="From2021-10-012022-09-30_custom_EquityOfferingSalesAgreementMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">20.3</ix:nonFraction></span> million after deducting
offering expenses) (2021: <span id="xdx_908_eus-gaap--SaleOfStockNumberOfSharesIssuedInTransaction_pip0_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zMmT4jfnutZ5" title="Number of common stock sold"><ix:nonFraction name="us-gaap:SaleOfStockNumberOfSharesIssuedInTransaction" contextRef="From2020-10-012021-09-30_custom_EquityOfferingSalesAgreementMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">5,634,576</ix:nonFraction></span> shares were sold for gross proceeds of $<span id="xdx_90C_ecustom--SoldForGrossProceedsAmount_pn5n6_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zBr3s8zoCXxc" title="Sold for gross proceeds amount"><ix:nonFraction name="avxl:SoldForGrossProceedsAmount" contextRef="From2020-10-012021-09-30_custom_EquityOfferingSalesAgreementMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">79.1</ix:nonFraction></span> million, net proceeds of $<span id="xdx_90E_eus-gaap--ProceedsFromIssuanceInitialPublicOffering_pn5n6_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zI1CybzBzu9d" title="Net proceed"><ix:nonFraction name="us-gaap:ProceedsFromIssuanceInitialPublicOffering" contextRef="From2020-10-012021-09-30_custom_EquityOfferingSalesAgreementMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">76.7</ix:nonFraction></span> million). At September
30, 2023, an amount of $<span id="xdx_90F_ecustom--SalesOfAgreementAmount_iI_pn5n6_c20230930_zosJik8ijhB" title="Sales of agreement amount"><ix:nonFraction name="avxl:SalesOfAgreementAmount" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">142.4</ix:nonFraction></span> million (2022: $<span id="xdx_907_ecustom--SalesOfAgreementAmount_iI_pn5n6_c20220930_zHv3V2kjN8Xe" title="Sales of agreement amount"><ix:nonFraction name="avxl:SalesOfAgreementAmount" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">142.4</ix:nonFraction></span> million) was registered pursuant to an effective registration statement. The Company
currently does not have access to sell shares of common stock under the Sales Agreement.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<ix:exclude><p id="xdx_239_zaitriM45YR6" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p></ix:exclude>

<ix:exclude><!-- Field: Page; Sequence: 83; Value: 1 -->
    <div id="xdx_23E_zvurMI3TgkHl" style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->16<!-- Field: /Sequence --></p></div>
    <div id="xdx_235_zMjTiBDofy27" style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page --></ix:exclude>

<ix:exclude><p id="xdx_239_zhNH2Su3Uwu3" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p></ix:exclude>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p><ix:exclude><p id="xdx_232_zidjmkGBaFi9" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Anavex
Life Sciences Corp.</span></p></ix:exclude>

<ix:exclude><p id="xdx_23D_zWyksHRGXyI6" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Notes
to the Consolidated Financial Statements</span></p></ix:exclude>

<ix:exclude><p id="xdx_230_zSK47PfoWW99" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30, 2023 &#8211; Page 17</span></p></ix:exclude>

<ix:exclude><p id="xdx_233_zxHeKCfyOO9" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0">&#160;</p></ix:exclude>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>2023
Purchase Agreement</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
February 3, 2023, the Company entered into a $150.0 million purchase agreement (the &#8220;2023 Purchase Agreement&#8221;) with Lincoln
Park Capital Fund, LLC (&#8220;Lincoln Park&#8221;), pursuant to which the Company has the right to sell and issue to Lincoln Park, and
Lincoln Park is obligated to purchase, up to $<span id="xdx_90F_ecustom--ValueOfSharesObligatedToPurchase_pn6n6_c20230202__20230203__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zcxkDCBcwoBl" title="Value of shares obligated to purchase"><ix:nonFraction name="avxl:ValueOfSharesObligatedToPurchase" contextRef="From2023-02-022023-02-03_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember" format="ixt:numdotdecimal" decimals="-6" scale="6" unitRef="USD">150</ix:nonFraction></span>.0 million in value of its shares of common stock from time to time over a three-year
period until February 3, 2026.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">In
consideration for entering into the 2023 Purchase Agreement, the Company issued to Lincoln Park <span id="xdx_909_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20230202__20230203__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_z8aVciu8dKa4" title="Share issued for offering, shares"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodSharesNewIssues" contextRef="From2023-02-022023-02-03_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">75,000</ix:nonFraction></span> shares of common stock as a commitment
fee (the &#8220;initial commitment shares&#8221;) and agreed to issue up to an additional <span id="xdx_905_ecustom--NumberOfSharesObligatedToPurchaseProrataBasic_pip0_c20230202__20230203__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zDmvYDmRpIR4" title="Pro rata basic number of shares obligated to purchase"><ix:nonFraction name="avxl:NumberOfSharesObligatedToPurchaseProrataBasic" contextRef="From2023-02-022023-02-03_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">75,000</ix:nonFraction></span> shares pro rata, when and if, Lincoln
Park purchased, at the Company&#8217;s discretion, the $<span id="xdx_904_eus-gaap--ProceedsFromIssuanceOrSaleOfEquity_pn6n6_c20230202__20230203__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zWtvzgAbQT47" title="Proceeds from issuance or sale of equity"><ix:nonFraction name="us-gaap:ProceedsFromIssuanceOrSaleOfEquity" contextRef="From2023-02-022023-02-03_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember" format="ixt:numdotdecimal" decimals="-6" scale="6" unitRef="USD">150</ix:nonFraction></span>.0 million aggregate commitment. The Company determined the fair value of
the initial commitment shares was $<span id="xdx_90C_ecustom--FairValueOfInitialCommitment_iI_pn5n6_c20230930_z4HQFCRySBs8" title="Fair value of the initial commitment"><ix:nonFraction name="avxl:FairValueOfInitialCommitment" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">0.8</ix:nonFraction></span> million with reference to the closing price of the Company&#8217;s shares on the Purchase Agreement
date. In addition, the Company incurred third party expenses of $<span id="xdx_900_ecustom--IncurredExpenses_iI_pn5n6_c20230930_zqBMreamcBK4" title="Incurred expenses"><ix:nonFraction name="avxl:IncurredExpenses" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">0.1</ix:nonFraction></span> million in connection with entering into the Purchase Agreement.
These amounts were expensed to other financing expense on the statements of operations during the year ended September 30, 2023.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">During
the year ended September 30, 2023, the Company issued to Lincoln Park an aggregate of <span id="xdx_906_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockIncludingCommitmentSharesMember_zjTYlplPSAh2" title="Number of shares issued, shares"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodSharesNewIssues" contextRef="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockIncludingCommitmentSharesMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">3,288,943</ix:nonFraction></span> (2022: <span id="xdx_907_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockIncludingCommitmentSharesMember_z6LOpIPL6A33" title="Number of shares issued, shares"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodSharesNewIssues" contextRef="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockIncludingCommitmentSharesMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">0</ix:nonFraction></span>) shares of common stock under
the 2023 Purchase Agreement, including <span id="xdx_902_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockExcludingCommitmentSharesMember_zKHtPnsEnjXa" title="Number of shares issued, shares"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodSharesNewIssues" contextRef="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockExcludingCommitmentSharesMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">3,275,000</ix:nonFraction></span> (2022: <span id="xdx_90A_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockExcludingCommitmentSharesMember_zYwnI6VFVwnc" title="Number of shares issued, shares"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodSharesNewIssues" contextRef="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockExcludingCommitmentSharesMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">0</ix:nonFraction></span>) shares of common stock for aggregate proceeds of $<span id="xdx_90D_eus-gaap--StockIssuedDuringPeriodValueNewIssues_pn5n6_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zzlbzAywYWSf" title="Number of shares issued, value"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodValueNewIssues" contextRef="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">27.9</ix:nonFraction></span> million (2022: $<span id="xdx_904_eus-gaap--StockIssuedDuringPeriodValueNewIssues_pn5n6_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zaJiVBhsgBWg" title="Number of shares issued, value"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodValueNewIssues" contextRef="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">0</ix:nonFraction></span>)
and&#160;<span id="xdx_907_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommitmentSharesMember_znaRV435uB97" title="Number of shares issued, shares"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodSharesNewIssues" contextRef="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommitmentSharesMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">13,943</ix:nonFraction></span>&#160;(2022:&#160;<span id="xdx_900_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommitmentSharesMember_znqFy6tpohz1" title="Number of shares issued, shares"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodSharesNewIssues" contextRef="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommitmentSharesMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">0</ix:nonFraction></span>) commitment shares.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">At
September 30, 2023, an amount of $<span id="xdx_903_eus-gaap--StockIssuedDuringPeriodValueOther_pn5n6_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zO9v6gY7XRR7" title="Amount of shares remain available"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodValueOther" contextRef="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">122.1</ix:nonFraction></span> million remained available under the 2023 Purchase Agreement.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>2019
Purchase Agreement</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
June 7, 2019, the Company entered into a $50.0 million purchase agreement (the &#8220;2019 Purchase Agreement&#8221;) with Lincoln Park,
as amended on July 1, 2020, pursuant to which the Company had the right to sell and issue to Lincoln Park, and Lincoln Park was obligated
to purchase, up to $<span id="xdx_90E_ecustom--ValueOfSharesObligatedToPurchase_pn6n6_c20230202__20230203__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zcrfomPkYdqb" title="Value of shares obligated to purchase"><ix:nonFraction name="avxl:ValueOfSharesObligatedToPurchase" contextRef="From2023-02-022023-02-03_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember" format="ixt:numdotdecimal" decimals="-6" scale="6" unitRef="USD">50</ix:nonFraction></span>.0 million in value of its shares of common stock from time to time over a three-year period until July 1, 2022.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">During
the year ended September 30, 2023 and 2022, the Company did not issue any shares to Lincoln Park under the 2019 Purchase Agreement.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">During
the year ended September 30, 2021, the Company issued to Lincoln Park an aggregate of <span id="xdx_903_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockIncludingCommitmentSharesMember_znOth4NjnOii" title="Number of shares issued, shares"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodSharesNewIssues" contextRef="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockIncludingCommitmentSharesMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">4,086,209</ix:nonFraction></span> shares of common stock under the 2019
Purchase Agreement, including <span id="xdx_901_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockExcludingCommitmentSharesMember_zT70L5cMjiab" title="Number of shares issued, shares"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodSharesNewIssues" contextRef="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockExcludingCommitmentSharesMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">4,007,996</ix:nonFraction></span> shares of common stock for an aggregate purchase price of $<span id="xdx_905_eus-gaap--StockIssuedDuringPeriodValueNewIssues_pn5n6_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__us-gaap--CommonStockMember_zhdeqeVovxv4" title="Number of shares issued, value"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodValueNewIssues" contextRef="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_us-gaap_CommonStockMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">24.1</ix:nonFraction></span> million and <span id="xdx_905_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommitmentSharesMember_zNPOHsOEFG8g" title="Number of shares issued, shares"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodSharesNewIssues" contextRef="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_custom_CommitmentSharesMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">78,213</ix:nonFraction></span> commitment
shares.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">At
September 30, 2023 and 2022, <span id="xdx_907_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_do_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zxh1eYR61Yfc" title="Number of shares issued, shares"><span id="xdx_901_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_do_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zTTuLXokmTC5" title="Number of shares issued, shares"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodSharesNewIssues" contextRef="From2022-10-012023-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember" format="ixt-sec:numwordsen" decimals="INF" scale="0" unitRef="Shares"><ix:nonFraction name="us-gaap:StockIssuedDuringPeriodSharesNewIssues" contextRef="From2021-10-012022-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember" format="ixt-sec:numwordsen" decimals="INF" scale="0" unitRef="Shares">no</ix:nonFraction></ix:nonFraction></span></span> shares remained available for issuance under the 2019 Purchase Agreement.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:CommitmentsDisclosureTextBlock"><p id="xdx_802_eus-gaap--CommitmentsDisclosureTextBlock_zE2pkYALuI52" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
6&#9;<span id="xdx_82F_zcntuv9Owit">Commitments and Contingencies</span></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Lease</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">The
Company leases office space under an operating lease with an initial term of <span id="xdx_909_eus-gaap--OperatingLeaseWeightedAverageRemainingLeaseTerm1_iI_dtM_c20230930_zGILsxUCfssh" title="Operating lease term"><ix:nonNumeric contextRef="AsOf2023-09-30" format="ixt-sec:durmonth" name="us-gaap:OperatingLeaseWeightedAverageRemainingLeaseTerm1">12</ix:nonNumeric></span> months or less. Under the terms of the office lease,
the Company is required to pay its proportionate share of operating costs. </span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">The
operating lease costs were as follows (in thousands):</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<ix:exclude><p id="xdx_23A_zvWBWPRlWsEf" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif"></span></p></ix:exclude>

<ix:exclude><!-- Field: Page; Sequence: 84; Value: 1 -->
    <div id="xdx_23E_zVoxEUJtfHP8" style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->17<!-- Field: /Sequence --></p></div>
    <div id="xdx_23F_ziLKN4kmPz3d" style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page --></ix:exclude>

<ix:exclude><p id="xdx_231_zlu6YJrHxqhk" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p></ix:exclude>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"></p><ix:exclude><p id="xdx_23B_zKgPGjHWdF5l" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Anavex
Life Sciences Corp.</span></p></ix:exclude>

<ix:exclude><p id="xdx_23D_zKJpTKebDbp8" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Notes
to the Consolidated Financial Statements</span></p></ix:exclude>

<ix:exclude><p id="xdx_231_zOP26MvpdHuk" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30, 2023 &#8211; Page 18</span></p></ix:exclude>

<ix:exclude><p id="xdx_237_zpp4kBHZSN27" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p></ix:exclude>

<ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:LeaseCostTableTextBlock"><table cellspacing="0" cellpadding="0" id="xdx_892_eus-gaap--LeaseCostTableTextBlock_pn3n3_zebQe0HUsBil" summary="xdx: Disclosure - Commitments and Contingencies (Details)" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <tr style="vertical-align: bottom">
    <td style="text-align: left"><span id="xdx_8BD_zRdYsDhim6L" style="display: none">Schedule of operating lease costs</span></td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_497_20221001__20230930_zoFz6uIyoz5h" style="text-align: center">&#160;</td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_497_20211001__20220930_zWLZSQljBpKc" style="text-align: center">&#160;</td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_496_20201001__20210930_zMlBeHRgn1ej" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="11" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>September
    30,</b></span></td></tr>
  <tr style="vertical-align: bottom">
    <td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2023</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2022</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2021</b></span></td></tr>
  <tr id="xdx_400_eus-gaap--OperatingLeaseCost_zNr7fwUnSpa" style="vertical-align: bottom; background-color: #CCEEFF">
    <td style="width: 55%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Operating lease costs</span></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:OperatingLeaseCost" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">118</ix:nonFraction></span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:OperatingLeaseCost" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">73</ix:nonFraction></span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:OperatingLeaseCost" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">131</ix:nonFraction></span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  </table>

</ix:nonNumeric><p id="xdx_8A5_zYMkVcWgWcFj" style="margin-top: 0; margin-bottom: 0">&#160;<span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Employee
401(k) Benefit Plan</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">The
Company has a defined-contribution savings plan under Section 401(k) of the Internal Revenue Code. The plan covers all United States
based employees. United States based employees eligible to participate in the plan may contribute up to the current statutory limits
under the Internal Revenue Service regulations. The 401(k) plan permits the Company to make additional matching contributions on behalf
of contributing employees. </span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">During
the year ended September 30, 2023, the Company made matching contributions under the 401(k) plan as follows (in thousands):</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 9pt Sans-Serif; margin: 0; color: Red"></p>

<ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:DefinedContributionPlanDisclosuresTableTextBlock"><table cellspacing="0" cellpadding="0" id="xdx_89F_eus-gaap--DefinedContributionPlanDisclosuresTableTextBlock_pn3n3_z6GAoPcUR2E" summary="xdx: Disclosure - Commitments and Contingencies (Details 1)" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <tr style="vertical-align: bottom">
    <td style="text-align: left"><span id="xdx_8B6_zNZ0ix4JlNLb" style="display: none">Schedule of contributions under the  plan</span></td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_497_20221001__20230930_zA0qushBeCO8" style="text-align: center">&#160;</td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_497_20211001__20220930_zj5JX4iHu8rg" style="text-align: center">&#160;</td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_496_20201001__20210930_zJ6NvaX8QTVe" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="11" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>September
    30,</b></span></td></tr>
  <tr style="vertical-align: bottom">
    <td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2023</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2022</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2021</b></span></td></tr>
  <tr id="xdx_40C_eus-gaap--PensionContributions_zAjEbuXkDcDj" style="vertical-align: bottom; background-color: #CCEEFF">
    <td style="width: 55%"><p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Contributions
                           to 401(k) plan</span></p></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:PensionContributions" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">232</ix:nonFraction></span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:PensionContributions" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">158</ix:nonFraction></span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:PensionContributions" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">129</ix:nonFraction></span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  </table>
<p style="font: 9pt Sans-Serif; margin: 0; color: Red"></p>

</ix:nonNumeric><p id="xdx_8AB_zFJSuoNaYAbd" style="font: 10pt Times New Roman, Times, Serif; margin: 0; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Litigation</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; background-color: white">The
Company is subject to claims and legal proceedings that arise in the ordinary course of business. Such matters are inherently uncertain,
and there can be no guarantee that the outcome of any such matter will be decided favorably to the Company or that the resolution of
any such matter will not have a material adverse effect upon the Company&#8217;s consolidated financial statements. The Company does
not believe that any of such pending claims and legal proceedings will have a material adverse effect on its consolidated financial statements.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Share
Purchase Warrants</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">At
September 30, 2023 and 2022, the Company had <span id="xdx_905_eus-gaap--ClassOfWarrantOrRightOutstanding_iI_pip0_c20230930_zU9Dso551HI8" title="Warrants outstanding"><span id="xdx_909_eus-gaap--ClassOfWarrantOrRightOutstanding_iI_pip0_c20220930_zaTuvrBJTgF3" title="Warrants outstanding"><ix:nonFraction name="us-gaap:ClassOfWarrantOrRightOutstanding" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares"><ix:nonFraction name="us-gaap:ClassOfWarrantOrRightOutstanding" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">160,000</ix:nonFraction></ix:nonFraction></span></span> warrants outstanding at a weighted average exercise price of $<span id="xdx_909_ecustom--WarrantsOutstandingWeightedAverageExercise_iI_pip0_c20230930_z3kK5IwtA6el" title="Warrants outstanding weighted average exercise price"><span id="xdx_907_ecustom--WarrantsOutstandingWeightedAverageExercise_iI_pip0_c20220930_z5jtuo1qpm66" title="Warrants outstanding weighted average exercise price"><ix:nonFraction name="avxl:WarrantsOutstandingWeightedAverageExercise" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares"><ix:nonFraction name="avxl:WarrantsOutstandingWeightedAverageExercise" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">3.72</ix:nonFraction></ix:nonFraction></span></span> as follows:</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="avxl:ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock"><table cellpadding="0" cellspacing="0" id="xdx_89E_ecustom--ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock_zKmN5o46PFt7" summary="xdx: Disclosure - Commitments and Contingencies (Details 2)" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
<td colspan="3" style="text-align: left"><span id="xdx_8B6_zdQIUyosHM7i" style="display: none">Schedule of share purchase warrants outstanding</span></td>
<td style="text-align: center">&#160;</td>
<td colspan="3" style="text-align: center">&#160;</td>
<td style="text-align: center">&#160;</td>
<td colspan="3" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Number</span></td>
<td style="text-align: center; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Exercise Price</span></td>
<td style="text-align: center; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Expiry Date</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants1Member_z7DIAed1ljy5" title="Number of warrants outstanding" style="width: 26%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber" contextRef="AsOf2023-09-30_custom_PurchaseWarrants1Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">150,000</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 8%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants1Member_zSEBrQgKsBAa" title="Exercise Price" style="width: 26%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_custom_PurchaseWarrants1Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">3.17</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 8%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 26%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_906_eus-gaap--WarrantsAndRightsOutstandingMaturityDate_iI_dd_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants1Member_z4XXQCR7NqKd" title="Expiry Date"><ix:nonNumeric contextRef="AsOf2023-09-30_custom_PurchaseWarrants1Member" format="ixt:datemonthdayyearen" name="us-gaap:WarrantsAndRightsOutstandingMaturityDate">May 6, 2024</ix:nonNumeric></span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants2Member_zek8ir0OxIK2" title="Number of warrants outstanding" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber" contextRef="AsOf2023-09-30_custom_PurchaseWarrants2Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">10,000</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants2Member_zckHC5eaRJ0f" title="Exercise Price" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_custom_PurchaseWarrants2Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">12.00</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_903_eus-gaap--WarrantsAndRightsOutstandingMaturityDate_iI_dd_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants2Member_zCjIeYOFUu0j" title="Expiry Date"><ix:nonNumeric contextRef="AsOf2023-09-30_custom_PurchaseWarrants2Member" format="ixt:datemonthdayyearen" name="us-gaap:WarrantsAndRightsOutstandingMaturityDate">April 21, 2026</ix:nonNumeric></span></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_iI_pip0_c20230930_z1GBMONfXrj9" title="Number of warrants outstanding" style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">160,000</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; text-align: right"></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 12pt Times New Roman, Times, Serif; padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 12pt Times New Roman, Times, Serif; padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font: 12pt Times New Roman, Times, Serif; text-align: right"></td>
<td style="font: 12pt Times New Roman, Times, Serif; padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



</ix:nonNumeric><p id="xdx_8A9_znw7vZXUMsdd" style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 42.55pt; text-align: left; text-indent: -0.8pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Stock&#8211;based
Compensation Plan</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>2015
Stock Option Plan</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
September 18, 2015, the Company&#8217;s board of directors approved a 2015 Omnibus Incentive Plan (the &#8220;2015 Plan&#8221;), which
provided for the grant of stock options and restricted stock awards to directors, officers, employees and consultants of the Company.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
maximum number of our common shares reserved for issue under the plan was <span id="xdx_90D_eus-gaap--CommonStockCapitalSharesReservedForFutureIssuance_iI_pip0_c20230930__us-gaap--PlanNameAxis__custom--StockOptionPlan2015Member_zZgMGE32sSjk" title="Maximum number of common shares reserved for future issuance"><ix:nonFraction name="us-gaap:CommonStockCapitalSharesReservedForFutureIssuance" contextRef="AsOf2023-09-30_custom_StockOptionPlan2015Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">6,050,553</ix:nonFraction></span> shares, subject to adjustment in the event of a change
of the Company&#8217;s capitalization.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;<b><i>&#160;</i></b></span></p>

<ix:exclude><p id="xdx_233_zy4I2yocx8vk" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i></i></b></span></p></ix:exclude>

<ix:exclude><!-- Field: Page; Sequence: 85; Value: 1 -->
    <div id="xdx_232_zUfyDHmhdsW1" style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p id="xdx_239_zJaad3g1YGL" style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->18<!-- Field: /Sequence --></p></div>
    <div id="xdx_23D_zxzJAgmvzBG3" style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page --></ix:exclude>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span><b></b></p><ix:exclude><p id="xdx_232_zG654rEndoMa" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0">&#160;</p></ix:exclude>

<ix:exclude><p id="xdx_231_z2IpAtopnFkd" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Anavex
Life Sciences Corp.</span></p></ix:exclude>

<ix:exclude><p id="xdx_23E_z1C6G6cUx05f" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Notes
to the Consolidated Financial Statements</span></p></ix:exclude>

<ix:exclude><p id="xdx_237_zwDkWuLoVoQg" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30, 2023 &#8211; Page 19</span></p></ix:exclude>

<ix:exclude><p id="xdx_232_zSQcQSZvzhmc" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p></ix:exclude>

<p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>2019
Stock Option Plan</i></b></span></span></p>

<p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
January 15, 2019, the Board approved the 2019 Omnibus Incentive Plan (the &#8220;2019 Plan&#8221;), which provides for the grant of stock
options and restricted stock awards to directors, officers, employees, consultants and advisors of the Company.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
maximum number of our common shares reserved for issue under the plan was <span id="xdx_904_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_pip0_c20221001__20230930__us-gaap--PlanNameAxis__custom--StockOptionPlan2019Member_zE2xKSnfxfMj" title="Additional shares of common stock available for issuance"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized" contextRef="From2022-10-012023-09-30_custom_StockOptionPlan2019Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">6,000,000</ix:nonFraction></span> shares, subject to adjustment in the event of a change
of the Company&#8217;s capitalization.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">During
the year ended September 30, 2022, <span id="xdx_90D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod_pip0_c20211001__20220930__us-gaap--PlanNameAxis__custom--StockOptionPlan2022Member_zPiZBJkKUDba" title="Option granted"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod" contextRef="From2021-10-012022-09-30_custom_StockOptionPlan2022Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">406,453</ix:nonFraction></span> options previously available under the 2019 Plan and the 2015 Plan became available under
the 2022 Plan (as defined below).</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>2022
Stock Option Plan</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
March 25, 2022, the Board approved the 2022 Omnibus Incentive Plan (the &#8220;2022 Plan&#8221;). The 2022 Plan was approved by stockholders
on May 24, 2022. Under the terms of the 2022 Plan, <span id="xdx_908_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_pip0_c20220324__20220325__us-gaap--PlanNameAxis__custom--StockOptionPlan2022Member_zCVPF6lGfzz6" title="Additional shares of common stock available for issuance"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized" contextRef="From2022-03-242022-03-25_custom_StockOptionPlan2022Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">10,000,000</ix:nonFraction></span> additional shares of Common Stock will be available for issuance under
the plan, in addition to the shares available under the 2019 Plan and the 2015 Plan. Any awards outstanding under a previous stock option
plan will remain subject to and be paid under such plan, and any shares subject to outstanding awards under a previous plan that subsequently
cease to be subject to such awards (other than by reason of settlement of the awards in shares) will automatically become available for
issuance under the 2022 Plan.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
2022 Plan provides that it may be administered by the Board, or the Board may delegate such responsibility to a committee. The exercise
price will be determined by the Board at the time of grant shall be at least equal to the fair market value on such date. If the grantee
is a 10% stockholder on the grant date, then the exercise price shall not be less than 110% of fair market value of the Company&#8217;s
shares of common stock on the grant date. Stock options may be granted under the 2022 Plan for an exercise period of up to ten years
from the date of grant of the option or such lesser periods as may be determined by the Board, subject to earlier termination in accordance
with the terms of the 2022 Plan. At September 30, 2023, <span id="xdx_904_ecustom--OptionIssued_pip0_c20221001__20230930_zECMzajbkxMi" title="Option issued"><ix:nonFraction name="avxl:OptionIssued" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">3,849,917</ix:nonFraction></span> options had been issued under the 2022 Plan and <span id="xdx_900_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_iI_pip0_c20230930__us-gaap--PlanNameAxis__custom--StockOptionPlan2022Member_zT6pYBZ4Zee1" title="Option available issue"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant" contextRef="AsOf2023-09-30_custom_StockOptionPlan2022Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">6,661,535</ix:nonFraction></span> options were
available for issue under the 2022 Plan, subject to stockholder approval.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
following summarizes information about stock option activity during the years ended September 30, 2023 and 2022:</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:ScheduleOfStockOptionsRollForwardTableTextBlock"><table cellpadding="0" cellspacing="0" id="xdx_890_eus-gaap--ScheduleOfStockOptionsRollForwardTableTextBlock_zahdwjh2ktsa" summary="xdx: Disclosure - Commitments and Contingencies (Details 3)" style="font: 9.5pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span id="xdx_8B4_zBRZ0wob6U9d" style="display: none">Schedule of stock option activity</span></td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted Average</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Average Grant</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Aggregate intrinsic</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Number of</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Exercise Price</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Date Fair Value</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">value</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Options</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">($)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">($)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">($)</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 18%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Outstanding,
September 30, 2021</span></td>
<td style="width: 3%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iS_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zaQEDt8Geqwg" title="Number of options, Outstanding beginning balance" style="width: 16%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" contextRef="AsOf2021-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">11,330,903</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 3%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iS_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zvh9J0z6rNSg" title="Weighted average exercise price, Outstanding beginning balance" style="width: 16%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" contextRef="AsOf2021-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">5.74</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 3%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_iS_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zm8JuTSr9WZg" title="Weighted average grant date fair value, Outstanding beginning balance" style="width: 15%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0768">&#8212;</span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 3%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_iS_pp0p0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zMVx9451Ez4i" title="Aggregate intrinsic value, Outstanding beginning balance" style="width: 15%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" contextRef="AsOf2021-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="0" scale="0" unitRef="USD">140,132,451</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Granted</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zYDHLx1xNqd" title="Number of options, Granted" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">2,358,000</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_za6WMoclHJt6" title="Weighted average exercise price, Granted" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">10.13</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z12ur8IugGNa" title="Weighted average grant date fair value, Granted" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">7.07</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Forfeited</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_iN_pip0_di_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zzqgqYLwD0x8" title="Number of options, Forfeited" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod" contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">118,750</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98F_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zz0JNU8yhYOi" title="Weighted average exercise price, Forfeited" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice" contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">6.86</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zd5Dfy6k0HWb" title="Weighted average grant date fair value, Forfeited" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice" contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">5.23</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Exercised</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--StockIssuedDuringPeriodSharesStockOptionsExercised_iN_pip0_di_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zLVBhCdfo3v2" title="Number of options, Exercised" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:StockIssuedDuringPeriodSharesStockOptionsExercised" contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">400,537</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zNtv4tKDm84l" title="Weighted average exercise price, Exercised" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">2.52</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zyXGXeuunFo" title="Weighted average grant date fair value, Exercised" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice" contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">1.88</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_pp0p0" title="Aggregate intrinsic value, Exercised" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue" contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="0" scale="0" unitRef="USD">4,201,015</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Outstanding,
September 30, 2022</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_983_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iS_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zF1F2l3FFbvl" title="Number of options, Outstanding beginning balance" style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" contextRef="AsOf2022-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">13,169,616</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iS_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zDoB5pRDMJR8" title="Weighted average exercise price, Outstanding beginning balance" style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" contextRef="AsOf2022-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">6.61</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_iS_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zP01qsGKaijj" title="Weighted average grant date fair value, Outstanding beginning balance" style="border-bottom: Black 2.5pt double; font: normal 10pt Times New Roman, Times, Serif; text-align: right"><span style="font: normal 10pt Times New Roman, Times, Serif"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" contextRef="AsOf2022-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">4.96</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_iS_pp0p0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zoFSMXIeupJ3" title="Aggregate intrinsic value, Outstanding beginning balance" style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" contextRef="AsOf2022-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="0" scale="0" unitRef="USD">62,267,309</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Granted</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zdGzYZ6nAJ19" title="Number of options, Granted" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">1,959,000</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zZhiagjQKbJd" title="Weighted average exercise price, Granted" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">9.30</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_ziClWNBA0fig" title="Weighted average grant date fair value, Granted" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">6.60</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Expired</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Exercised</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_981_eus-gaap--StockIssuedDuringPeriodSharesStockOptionsExercised_iN_pip0_di_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zlKT4O9ITNx2" title="Number of options, Exercised" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:StockIssuedDuringPeriodSharesStockOptionsExercised" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">759,753</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zjRxv8zRZ3s6" title="Weighted average exercise price, Exercised" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">2.34</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_987_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z3bIctfsRpu9" title="Weighted average grant date fair value, Exercised" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">0.95</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_983_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_pp0p0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zumLJJKYvL95" title="Aggregate intrinsic value, Exercised" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="0" scale="0" unitRef="USD">4,629,026</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Forfeited</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_iN_pip0_di_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zcgXAyqtdxn7" title="Number of options, Forfeited" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">257,083</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z189xmJSdqYh" title="Weighted average exercise price, Forfeited" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">12.00</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98E_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zPz67mlunnO8" title="Weighted average grant date fair value, Forfeited" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">6.74</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Cancelled</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Outstanding,
September 30, 2023</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iE_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zwxfgYOA6xzc" title="Number of options, Outstanding ending balance" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">14,111,780</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iE_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zDKIrfhkqrwi" title="Weighted average exercise price, Outstanding ending balance" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">7.12</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_iE_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z8QNfw1Q0kMg" title="Weighted average grant date fair value,  Outstanding ending balance" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">5.27</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_iE_pp0p0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zevpgIbVICHg" title="Aggregate intrinsic value, Outstanding ending balance" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="0" scale="0" unitRef="USD">22,290,069</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Exercisable,
September 30, 2023</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zJW8NDpTVbOa" title="Number of options, Exercisable" style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">9,604,614</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zhq3b5hS8iE" title="Weighted average exercise price, Exercisable" style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">5.19</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z7ZLBQG8DOQ9" title="Weighted average grant date fair value, Exercisable" style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">3.94</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_iI_pp0p0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zde5865tfxlf" title="Aggregate intrinsic value, Exercisable" style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="0" scale="0" unitRef="USD">22,290,069</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



</ix:nonNumeric><p id="xdx_8AD_zEuKBqIga3vj" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
following summarizes information about stock options at September 30, 2023 by a range of exercise prices:</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock"><table cellpadding="0" cellspacing="0" id="xdx_89A_eus-gaap--ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_zEoDtaKA8WQ4" summary="xdx: Disclosure - Commitments and Contingencies (Details 4)" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
<td colspan="3" style="font-size: 10pt; text-align: left"><span id="xdx_8B5_zZ1azt0WqCG3" style="display: none">Schedule of summarizes information about stock options</span></td>
<td style="font-size: 10pt">&#160;</td>
<td colspan="3" style="font-size: 10pt; text-align: center">&#160;</td>
<td style="font-size: 10pt">&#160;</td>
<td colspan="3" style="font-size: 10pt; text-align: center">&#160;</td>
<td>&#160;</td>
<td colspan="3" style="text-align: center">&#160;</td>
<td>&#160;</td>
<td colspan="3" style="text-align: center">&#160;</td>
<td style="font-size: 10pt">&#160;</td>
<td colspan="3" style="font-size: 10pt; text-align: center">&#160;</td>
<td style="font-size: 10pt">&#160;</td>
<td colspan="3" style="font-size: 10pt; text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom">
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">average</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom">
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Number of</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">remaining</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">average</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted</span></td></tr>
<tr style="vertical-align: bottom">
<td colspan="7" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Range of exercises
prices</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">outstanding</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">contractual</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">exercise</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Number of</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">average</span></td></tr>
<tr style="vertical-align: bottom">
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">From</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">To</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">options</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">life</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">price</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">vested options</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">exercise price</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zJYXBWgUxKda" title="Range of exercise prices, Lower range limit" style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">0.92</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_znfdhmj2ADy3" title="Range of exercise prices, Upper range limit" style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">3.00</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zik41maNOF0h" title="Number of outstanding options" style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">3,280,309</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_903_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zOoekuBKWZEa" title="Weighted average remaining contractual life"><ix:nonNumeric contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member" format="ixt-sec:duryear" name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2">4.74</ix:nonNumeric></span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zJmshsBbEIab" title="Weighted average exercise price" style="width: 10%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">2.39</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_987_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zbnUPrIBpwV2" title="Number of vested options" style="width: 10%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">3,280,309</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_z9mbrl6XrXf" title="Weighted average exercise price options vested" style="width: 10%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">2.39</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_986_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_z7Y8nycQuh9a" title="Range of exercise prices, Lower range limit" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">3.01</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98B_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_z086mh1eEJ4h" title="Range of exercise prices, Upper range limit" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">5.00</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zWp1gnuPFd1h" title="Number of outstanding options" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">2,017,500</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90D_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zfpbf6GJ6g7c" title="Weighted average remaining contractual life"><ix:nonNumeric contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member" format="ixt-sec:duryear" name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2">4.32</ix:nonNumeric></span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zCMjYCjifoc" title="Weighted average exercise price" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">3.28</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zw5cQQ4bQl4a" title="Number of vested options" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">2,017,500</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_ze2Cbpm9tHh3" title="Weighted average exercise price options vested" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">3.28</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zfnYJas5hHn5" title="Range of exercise prices, Lower range limit" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">5.01</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zjw2rHU2tdde" title="Range of exercise prices, Upper range limit" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">9.00</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zJwiUtbGVNFa" title="Number of outstanding options" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">5,260,054</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_903_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zv4ZErt5pUja" title="Weighted average remaining contractual life"><ix:nonNumeric contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member" format="ixt-sec:duryear" name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2">6.21</ix:nonNumeric></span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zAumZywNL2Bk" title="Weighted average exercise price" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">6.90</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zKxXBt473Zje" title="Number of vested options" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">3,304,137</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zr1Kzn0lL1M5" title="Weighted average exercise price options vested" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">6.10</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zLMY1YARIpUe" title="Range of exercise prices, Lower range limit" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">9.01</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_z4hniAZlE363" title="Range of exercise prices, Upper range limit" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">13.00</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zJdUNRWEL8Ql" title="Number of outstanding options" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">1,981,917</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90D_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zVADhDSFa35f" title="Weighted average remaining contractual life"><ix:nonNumeric contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member" format="ixt-sec:duryear" name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2">8.37</ix:nonNumeric></span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_z7Spxmdt2g87" title="Weighted average exercise price" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">10.55</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zm06iu99nx94" title="Number of vested options" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">480,584</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zVXTV9kNNHI3" title="Weighted average exercise price options vested" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">11.45</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zMWFZE1Vdnyc" title="Range of exercise prices, Lower range limit" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">13.01</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zoLuZjUZdnX4" title="Range of exercise prices, Upper range limit" style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">25.00</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_z8NHOEOWSvB9" title="Number of outstanding options" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">1,572,000</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zLQK7QouAmE9" title="Weighted average remaining contractual life"><ix:nonNumeric contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member" format="ixt-sec:duryear" name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2">7.49</ix:nonNumeric></span></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zTu44CHbESU8" title="Weighted average exercise price" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">18.29</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_982_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zekHKoPStc37" title="Number of vested options" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">522,084</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zaAU3Mj6dCX1" title="Weighted average exercise price options vested" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">18.57</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"></td>
<td style="padding-bottom: 2.5pt; font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"></td>
<td style="padding-bottom: 2.5pt; font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zt2AET0WMtzk" title="Number of outstanding options" style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">14,111,780</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90B_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zrvSy6PHWlcg" title="Weighted average remaining contractual life"><ix:nonNumeric contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember" format="ixt-sec:duryear" name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2">6.04</ix:nonNumeric></span></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zz5zxf8fZNo8" title="Weighted average exercise price" style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">7.12</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zQ4zwY5uofia" title="Number of vested options" style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="Shares">9,604,614</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zvNCPuWNKxpi" title="Weighted average exercise price options vested" style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice" contextRef="AsOf2023-09-30_us-gaap_StockOptionMember" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">5.19</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



</ix:nonNumeric><p id="xdx_8A4_zmiwvETXlO4e" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<ix:exclude><p id="xdx_237_zpuMhYMsJ6ta" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p></ix:exclude>

<ix:exclude><!-- Field: Page; Sequence: 86; Value: 1 -->
    <div id="xdx_230_zoEBaUlDhxUa" style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->19<!-- Field: /Sequence --></p></div>
    <div id="xdx_239_zsvTErEGxYTe" style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page --></ix:exclude>

<ix:exclude><p id="xdx_233_zqAdxB06ARwf" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p></ix:exclude>

<ix:exclude><p id="xdx_23F_z9zyIWsZDXB3" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font: 10pt Times New Roman, Times, Serif">Anavex
Life Sciences Corp.</span></p></ix:exclude>

<ix:exclude><p id="xdx_236_zv0WWtNzu9N7" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font: 10pt Times New Roman, Times, Serif">Notes
to the Consolidated Financial Statements</span></p></ix:exclude>

<ix:exclude><p id="xdx_238_zlvXIkwHakSj" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font: 10pt Times New Roman, Times, Serif">September
30, 2023 &#8211; Page 20</span></p></ix:exclude>


<ix:exclude><p id="xdx_239_zSVwsbpO2rn3" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p></ix:exclude>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
weighted average per share fair value of options vested during the year ended September 30, 2023 was $<span id="xdx_90F_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_pip0_c20221001__20230930_zhxiHcVEOz8" title="Weighted average grant date fair value of options vested"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">3.94</ix:nonFraction></span> (2022: $<span id="xdx_90F_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_pip0_c20211001__20220930_zQQWTKVXN7j2" title="Weighted average grant date fair value of options vested"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">4.69</ix:nonFraction></span>, 2021: $<span id="xdx_905_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_pip0_c20201001__20210930_zEZMrPGIxEC1" title="Weighted average grant date fair value of options vested"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="INF" scale="0" unitRef="USDPShares">2.54</ix:nonFraction></span>).
At September 30, 2023, the weighted average contractual life of options outstanding was <span id="xdx_903_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930_zBHZY8takBBa" title="Weighted average contractual life of options outstanding"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" format="ixt-sec:duryear" name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2">6.0</ix:nonNumeric></span> years (2022: <span id="xdx_905_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20211001__20220930_zTFCW5ySvsgf" title="Weighted average contractual life of options outstanding"><ix:nonNumeric contextRef="From2021-10-012022-09-30" format="ixt-sec:duryear" name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2">6.4</ix:nonNumeric></span> years) and for options exercisable
was <span id="xdx_904_eus-gaap--SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930_z7IOtwJb2Aoj" title="Options exercisable"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" format="ixt-sec:duryear" name="us-gaap:SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2">4.75</ix:nonNumeric></span> years (2022: <span id="xdx_904_eus-gaap--SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_dtY_c20211001__20220930_zEa7SxOeqOih" title="Options exercisable"><ix:nonNumeric contextRef="From2021-10-012022-09-30" format="ixt-sec:duryear" name="us-gaap:SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2">5.1</ix:nonNumeric></span> years).</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
aggregate intrinsic value is calculated as the difference between the exercise price of the underlying awards and the quoted market price
of the Company&#8217;s stock for the options that were in-the-money at September 30, 2023.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9;The
Company recognized stock-based compensation expense of $<span id="xdx_909_eus-gaap--AllocatedShareBasedCompensationExpense_pn5n6_c20221001__20230930_zH6p6tZw0jW" title="Share based compensation"><ix:nonFraction name="us-gaap:AllocatedShareBasedCompensationExpense" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">16.4</ix:nonFraction></span> million during the year ended September 30, 2023 (2022: $<span id="xdx_90A_eus-gaap--AllocatedShareBasedCompensationExpense_pn5n6_c20211001__20220930_zGbryIoD3SS9" title="Share based compensation"><ix:nonFraction name="us-gaap:AllocatedShareBasedCompensationExpense" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">18.4</ix:nonFraction></span> million; 2021:
$<span id="xdx_907_eus-gaap--AllocatedShareBasedCompensationExpense_pn5n6_c20201001__20210930_zksFCXqaXAHj" title="Share based compensation"><ix:nonFraction name="us-gaap:AllocatedShareBasedCompensationExpense" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">8.2</ix:nonFraction></span> million) in connection with the issuance and vesting &#9;of stock options in exchange for services. These amounts have been included
in general and &#9;administrative expenses and research and development expenses on the Company&#8217;s consolidated statements of &#9;operations
as follows (in thousands):</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p><p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"></p>

<p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"></p>


<ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock"><table cellpadding="0" cellspacing="0" id="xdx_893_eus-gaap--ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_pn3n3_zi05WuRK54V9" summary="xdx: Disclosure - Commitments and Contingencies (Details 5)" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
<td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; text-align: left; text-indent: -10pt"><span id="xdx_8B0_zVkn5OI5YY12" style="display: none">Schedule of general and administrative expenses and research and development expenses</span></td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="11" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30,</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">General
and administrative</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_98A_eus-gaap--ShareBasedCompensation_pn3n3_c20221001__20230930__us-gaap--IncomeStatementLocationAxis__us-gaap--GeneralAndAdministrativeExpenseMember_zlegHFiNw3u9" title="Total share based compensation" style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensation" contextRef="From2022-10-012023-09-30_us-gaap_GeneralAndAdministrativeExpenseMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">5,558</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensation_pn3n3_c20211001__20220930__us-gaap--IncomeStatementLocationAxis__us-gaap--GeneralAndAdministrativeExpenseMember_zt8VbpPKl4ri" title="Total share based compensation" style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensation" contextRef="From2021-10-012022-09-30_us-gaap_GeneralAndAdministrativeExpenseMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">7,129</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensation_pn3n3_c20201001__20210930__us-gaap--IncomeStatementLocationAxis__us-gaap--GeneralAndAdministrativeExpenseMember_ztXzYhbjPTtj" title="Total share based compensation" style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensation" contextRef="From2020-10-012021-09-30_us-gaap_GeneralAndAdministrativeExpenseMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">3,571</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98E_eus-gaap--ShareBasedCompensation_pn3n3_c20221001__20230930__us-gaap--IncomeStatementLocationAxis__us-gaap--ResearchAndDevelopmentExpenseMember_zxlwTaY7roA2" title="Total share based compensation" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensation" contextRef="From2022-10-012023-09-30_us-gaap_ResearchAndDevelopmentExpenseMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">10,812</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensation_pn3n3_c20211001__20220930__us-gaap--IncomeStatementLocationAxis__us-gaap--ResearchAndDevelopmentExpenseMember_zMnF2RIYqYD7" title="Total share based compensation" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensation" contextRef="From2021-10-012022-09-30_us-gaap_ResearchAndDevelopmentExpenseMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">11,250</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_987_eus-gaap--ShareBasedCompensation_pn3n3_c20201001__20210930__us-gaap--IncomeStatementLocationAxis__us-gaap--ResearchAndDevelopmentExpenseMember_zbbLNUWHcCQk" title="Total share based compensation" style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensation" contextRef="From2020-10-012021-09-30_us-gaap_ResearchAndDevelopmentExpenseMember" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">4,660</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total
stock-based compensation</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_983_eus-gaap--ShareBasedCompensation_pn3n3_c20221001__20230930_zBefjtLfXJBl" title="Total share based compensation" style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensation" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">16,370</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensation_pn3n3_c20211001__20220930_zJqVKJNEeNN2" title="Total share based compensation" style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensation" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">18,379</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensation_pn3n3_c20201001__20210930_zNPDO6PYdgbh" title="Total share based compensation" style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:ShareBasedCompensation" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">8,231</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



</ix:nonNumeric><p id="xdx_8A1_zEmZAKeGAs8d" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">An
amount of approximately $<span id="xdx_90F_eus-gaap--EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_iI_pn5n6_c20230930_zHwO246Nknc7" title="Remaining stock based compensation"><ix:nonFraction name="us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">14.1</ix:nonFraction> </span>million in stock-based compensation is expected to be recorded over the remaining term &#9;of such options
and warrants through fiscal 2026.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
fair value of each option and warrant award is estimated on the date of grant using the Black Scholes option pricing model based on the
following weighted average assumptions:</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="avxl:ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock"><table cellpadding="0" cellspacing="0" id="xdx_89D_ecustom--ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock_zN55WsDXEShe" summary="xdx: Disclosure - Commitments and Contingencies (Details 6)" style="font: 10.5pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span id="xdx_8B4_zaAFre5XkJXj" style="display: none">Schedule of weighted average assumptions for fair value of each option award</span></td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Risk-free
interest rate</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_pip0_dp_c20221001__20230930_zKO6cup4Qeu1" title="Risk-free interest rate"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="-2" unitRef="Pure">3.70</ix:nonFraction></span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_pip0_dp_c20211001__20220930_zHZHxDG4efy4" title="Risk-free interest rate"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="-2" unitRef="Pure">3.11</ix:nonFraction></span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_909_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_pip0_dp_c20201001__20210930_zT78UQ0afMp7" title="Risk-free interest rate"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="INF" scale="-2" unitRef="Pure">0.73</ix:nonFraction></span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Expected
life of options (years)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90F_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_dtY_c20221001__20230930_zQgzQUIlWFjg" title="Expected life of options (years)"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" format="ixt-sec:duryear" name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1">5.64</ix:nonNumeric></span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_908_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_dtY_c20211001__20220930_zMxT0K2f40o5" title="Expected life of options (years)"><ix:nonNumeric contextRef="From2021-10-012022-09-30" format="ixt-sec:duryear" name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1">5.57</ix:nonNumeric></span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_901_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_dtY_c20201001__20210930_zfLzebHEUPni" title="Expected life of options (years)"><ix:nonNumeric contextRef="From2020-10-012021-09-30" format="ixt-sec:duryear" name="us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1">5.74</ix:nonNumeric></span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Annualized
volatility</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_pip0_dp_c20221001__20230930_z5WfFe3kdgzj" title="Annualized volatility"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="-2" unitRef="Pure">85.13</ix:nonFraction></span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_pip0_dp_c20211001__20220930_zAKopGanU2f2" title="Annualized volatility"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="-2" unitRef="Pure">84.17</ix:nonFraction></span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_904_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_pip0_dp_c20201001__20210930_zQ9PnpHPDlV2" title="Annualized volatility"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="INF" scale="-2" unitRef="Pure">93.43</ix:nonFraction></span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Dividend
rate</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_pip0_dp_c20221001__20230930_zQJP91L18KX4" title="Dividend rate"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="INF" scale="-2" unitRef="Pure">0.00</ix:nonFraction></span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_909_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_pip0_dp_c20211001__20220930_z2gilqQmyEg5" title="Dividend rate"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="INF" scale="-2" unitRef="Pure">0.00</ix:nonFraction></span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_pip0_dp_c20201001__20210930_z90iEDkkPtbe" title="Dividend rate"><ix:nonFraction name="us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="INF" scale="-2" unitRef="Pure">0.00</ix:nonFraction></span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td></tr>
</table>



</ix:nonNumeric><p id="xdx_8A2_zyMT6BsApCPj" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
fair value of stock compensation charges recognized during the years ended September 30, 2023, 2022 and 2021 was determined with reference
to the quoted market price of the Company&#8217;s shares on the grant date.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<ix:exclude><p id="xdx_23E_ztDbLi3U4q19" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif"></span></p></ix:exclude>

<ix:exclude><!-- Field: Page; Sequence: 87; Value: 1 -->
    <div id="xdx_233_zVal9Y9UVdY5" style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->20<!-- Field: /Sequence --></p></div>
    <div id="xdx_232_zGuwtb8X0Ccc" style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page --></ix:exclude>

<ix:exclude><p id="xdx_239_zLF8pogZsr77" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p></ix:exclude>

<ix:exclude><p id="xdx_235_zNyNR7mkJwZ1" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Anavex
Life Sciences Corp.</span></p></ix:exclude>

<ix:exclude><p id="xdx_236_zYWijfm6hxU7" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font: 10pt Times New Roman, Times, Serif">Notes
to the Consolidated Financial Statements</span></p></ix:exclude>

<ix:exclude><p id="xdx_23F_zVWfSTi87Mib" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font: 10pt Times New Roman, Times, Serif">September
30, 2023 &#8211; Page 21</span></p></ix:exclude>


<ix:exclude><p id="xdx_23C_zT7BzPJek2T1" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p></ix:exclude>
<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif"></span></p>


</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:IncomeTaxDisclosureTextBlock"><p id="xdx_809_eus-gaap--IncomeTaxDisclosureTextBlock_zskvIWwUEx38" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
7&#9; &#9;<span id="xdx_82F_z9n0dvl8UTs4">Income Taxes</span> </b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company&#8217;s U.S. and foreign loss before income taxes are set forth below (in thousands):</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock"><table cellpadding="0" cellspacing="0" id="xdx_894_eus-gaap--ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock_pn3n3_z4sCfQjlSamk" summary="xdx: Disclosure - Income Taxes (Details)" style="font: 9.5pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
<td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left"><span id="xdx_8B0_zY6zjeyTPFke" style="display: none">Schedule of loss before
income taxes</span></td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_496_20221001_20230930" style="text-align: center">&#160;</td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_494_20211001_20220930" style="text-align: center">&#160;</td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_492_20201001_20210930" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr id="xdx_408_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">United
States</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">41,198</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">40,002</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">28,851</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_406_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_zSoEJlgOqv97" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Foreign</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">6,300</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">7,618</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">8,790</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_40A_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_z76oU3PPoFLf" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">47,498</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">47,620</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">37,641</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
</table>



</ix:nonNumeric><p id="xdx_8A6_znTzPaTwtQal" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
components of net deferred income tax assets as of September 30, 2023, 2022 and 2021 are as follows (in thousands):</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 12pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>

<ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock"><table cellpadding="0" cellspacing="0" id="xdx_893_eus-gaap--ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_pn3n3_z2nP6y5V9QFk" summary="xdx: Disclosure - Income Taxes (Details 1)" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
<td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left"><span id="xdx_8BF_zF3rKRkptpk8" style="display: none">Schedule of components of
net deferred income tax assets</span></td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_49D_20230930" style="text-align: center">&#160;</td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_493_20220930" style="text-align: center">&#160;</td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_498_20210930_zaE4q2jgcLma" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr id="xdx_40B_eus-gaap--DeferredTaxAssetsOperatingLossCarryforwards_iI_z9TlGYr5v4be" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net
operating loss carryforwards</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredTaxAssetsOperatingLossCarryforwards" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">46,462</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredTaxAssetsOperatingLossCarryforwards" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">46,208</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredTaxAssetsOperatingLossCarryforwards" contextRef="AsOf2021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">34,982</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_409_eus-gaap--DeferredTaxAssetsInProcessResearchAndDevelopment_iI_zEOjZKyH2Mn2" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development tax credit carryforwards</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">2,713</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">2,182</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment" contextRef="AsOf2021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,577</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_408_eus-gaap--DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_iI_zpUuEvXfHkF2" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Stock-based
compensation</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">18,593</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">13,373</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" contextRef="AsOf2021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">10,453</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_407_ecustom--DeferredTaxAssetsResearchAndDevelopmentCapitalization_iI_zXJnEltE20u1" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development capitalization</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:DeferredTaxAssetsResearchAndDevelopmentCapitalization" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">7,219</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1029">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1030">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_408_ecustom--DeferredTaxAssetsUnpaidCharges_iI_zX2XoiNZ1rjk" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Unpaid
charges</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:DeferredTaxAssetsUnpaidCharges" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,559</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:DeferredTaxAssetsUnpaidCharges" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">894</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:DeferredTaxAssetsUnpaidCharges" contextRef="AsOf2021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">89</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40A_eus-gaap--DeferredTaxAssetsGoodwillAndIntangibleAssets_iI_zQyMqOHHjd39" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Intangible
asset costs</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredTaxAssetsGoodwillAndIntangibleAssets" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">593</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredTaxAssetsGoodwillAndIntangibleAssets" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">388</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredTaxAssetsGoodwillAndIntangibleAssets" contextRef="AsOf2021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">323</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_403_eus-gaap--DeferredTaxAssetsUnrealizedCurrencyLosses_iI_zS92gCVLPkw" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Foreign
exchange and other</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredTaxAssetsUnrealizedCurrencyLosses" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">49</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredTaxAssetsUnrealizedCurrencyLosses" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">44</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredTaxAssetsUnrealizedCurrencyLosses" contextRef="AsOf2021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">62</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40B_eus-gaap--DeferredTaxAssetsValuationAllowance_iNI_di_z51AqN69x9S5" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Valuation
allowance of deferred tax assets</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:DeferredTaxAssetsValuationAllowance" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">77,188</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:DeferredTaxAssetsValuationAllowance" contextRef="AsOf2022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">63,089</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:DeferredTaxAssetsValuationAllowance" contextRef="AsOf2021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">47,486</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_40E_eus-gaap--DeferredTaxAssetsNet_iI_zTZlhwMjO2M1" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net
deferred tax assets</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1048">&#8212;</span></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1049">&#8212;</span></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1050">&#8212;</span></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>


</ix:nonNumeric><p id="xdx_8A7_zl9mCbge1VK9" style="font: 12pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">A
reconciliation of income tax expense at the statutory federal income tax rate and income taxes as reflected in the consolidated financial
statements for the years ended September 30, 2023, 2022 and 2021 is as follows (in thousands):</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 12pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>

<ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock"><table cellpadding="0" cellspacing="0" id="xdx_89E_eus-gaap--ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_pn3n3_zsVzljCQ03c6" summary="xdx: Disclosure - Income Taxes (Details 2)" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
<td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><span id="xdx_8BA_z701s73Iniah" style="display: none">Schedule
of reconciliation of income tax expense</span></td>
<td>&#160;</td>
<td colspan="3" id="xdx_49C_20221001__20230930_z6poV6auzo5i" style="text-align: center">&#160;</td>
<td>&#160;</td>
<td colspan="3" id="xdx_495_20211001__20220930_zgRuwYwJDgEf" style="text-align: center">&#160;</td>
<td>&#160;</td>
<td colspan="3" id="xdx_493_20201001__20210930_zLPqPPjEels4" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr id="xdx_40D_eus-gaap--IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_zRekekCgXmOh" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Income
tax benefit at statutory federal rate</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">9,975</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">10,000</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">7,934</ix:nonFraction></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_40C_eus-gaap--IncomeTaxReconciliationForeignIncomeTaxRateDifferential_ziOeNTMw5XHh" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Foreign
income taxed at other rates</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1058">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeTaxReconciliationForeignIncomeTaxRateDifferential" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">170</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeTaxReconciliationForeignIncomeTaxRateDifferential" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">353</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_408_ecustom--PermanentDifferencesRelatingToStockBasedCompensation_zMH8Yb6MSbN9" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Permanent
differences relating to stock based compensation</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="avxl:PermanentDifferencesRelatingToStockBasedCompensation" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">601</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="avxl:PermanentDifferencesRelatingToStockBasedCompensation" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">714</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="avxl:PermanentDifferencesRelatingToStockBasedCompensation" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">4,379</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_40A_eus-gaap--EffectiveIncomeTaxRateReconciliationGiltiAmount_zuYDNTfabwmg" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Permanent
differences relating to GILTI inclusion</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:EffectiveIncomeTaxRateReconciliationGiltiAmount" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">165</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1067">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1068">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_401_ecustom--PermanentDifferencesRelatingToSection162m_zopWtm3badqj" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Permanent
differences relating to Section 162(m)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1070">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1071">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:PermanentDifferencesRelatingToSection162m" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">816</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40F_eus-gaap--IncomeTaxReconciliationOtherAdjustments_i_pp0p0" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Other
permanent differences</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncomeTaxReconciliationOtherAdjustments" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">273</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1075">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncomeTaxReconciliationOtherAdjustments" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">741</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_401_ecustom--AdjustmentToTaxAssetsBasedOnSection382_zAIrAcBONkAk" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Adjustment
to tax assets based on Section 382</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1078">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1079">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:AdjustmentToTaxAssetsBasedOnSection382" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">3,330</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_408_ecustom--IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet_zlsUXX2azvUd" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development credits, net</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="avxl:IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">37</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">232</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="avxl:IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">1,042</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_405_eus-gaap--IncomeTaxReconciliationStateAndLocalIncomeTaxes_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">State
and local taxes</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeTaxReconciliationStateAndLocalIncomeTaxes" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">4,122</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeTaxReconciliationStateAndLocalIncomeTaxes" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">4,975</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(<ix:nonFraction name="us-gaap:IncomeTaxReconciliationStateAndLocalIncomeTaxes" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" sign="-" unitRef="USD">7,022</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_40C_eus-gaap--IncomeTaxReconciliationPriorYearIncomeTaxes_i_pp0p0" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Adjustment
to true up to prior years' tax provision</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncomeTaxReconciliationPriorYearIncomeTaxes" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">206</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncomeTaxReconciliationPriorYearIncomeTaxes" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">24</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncomeTaxReconciliationPriorYearIncomeTaxes" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">48</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40B_eus-gaap--IncomeTaxReconciliationChangeInEnactedTaxRate_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Effect
of change in statutory tax rates</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1094">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1095">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncomeTaxReconciliationChangeInEnactedTaxRate" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">216</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_408_eus-gaap--TaxesExcludingIncomeAndExciseTaxes_i_pp0p0" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">State
minimum and excise taxes</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1098">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:TaxesExcludingIncomeAndExciseTaxes" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">358</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:TaxesExcludingIncomeAndExciseTaxes" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">268</ix:nonFraction></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40C_eus-gaap--IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Change
in valuation allowances</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">14,098</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">15,603</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">13,495</ix:nonFraction></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_405_eus-gaap--DeferredIncomeTaxExpenseBenefit_i_pp0p0" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Income
tax expense</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredIncomeTaxExpenseBenefit" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">7</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredIncomeTaxExpenseBenefit" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">358</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><ix:nonFraction name="us-gaap:DeferredIncomeTaxExpenseBenefit" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-3" scale="3" unitRef="USD">268</ix:nonFraction></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>


</ix:nonNumeric><p id="xdx_8A4_z3qn8d22c1X8" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<ix:exclude><p id="xdx_239_z2XjzWZuvTL1" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif"></span></p></ix:exclude>

<ix:exclude><!-- Field: Page; Sequence: 87; Value: 1 -->
    <div id="xdx_235_zhdY1oKcQrUj" style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->21<!-- Field: /Sequence --></p></div>
    <div id="xdx_23C_zqTvJE1HXBxe" style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page --></ix:exclude>

<ix:exclude><p id="xdx_23F_zuSAJD77Zi66" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p></ix:exclude>

<ix:exclude><p id="xdx_236_zDv7go9da03h" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Anavex
Life Sciences Corp.</span></p></ix:exclude>

<ix:exclude><p id="xdx_239_zFS2p0cBNPs3" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font: 10pt Times New Roman, Times, Serif">Notes
to the Consolidated Financial Statements</span></p></ix:exclude>

<ix:exclude><p id="xdx_230_zVSOMwbZY407" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font: 10pt Times New Roman, Times, Serif">September
30, 2023 &#8211; Page 22</span></p></ix:exclude>

<ix:exclude><p id="xdx_236_z5zlcgDamPJ2" style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p></ix:exclude>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">As
of September 30, 2023, the Company had U.S. federal net operating loss carryforwards of approximately $<span id="xdx_90A_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20230930__us-gaap--IncomeTaxAuthorityAxis__custom--FederalMember_zosExQ9Ni2ve" title="Operating loss carryforwards"><ix:nonFraction name="us-gaap:OperatingLossCarryforwards" contextRef="AsOf2023-09-30_custom_FederalMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">126.3</ix:nonFraction></span> million (2022: $<span id="xdx_90A_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20220930__us-gaap--IncomeTaxAuthorityAxis__custom--FederalMember_znacYwgHTTK7" title="Operating loss carryforwards"><ix:nonFraction name="us-gaap:OperatingLossCarryforwards" contextRef="AsOf2022-09-30_custom_FederalMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">123.4</ix:nonFraction></span> million)
of which <span id="xdx_905_ecustom--OperatingLossCarryforwardsDescription_c20221001__20230930__us-gaap--IncomeTaxAuthorityAxis__custom--FederalMember_z90eQ9gTvLZ2" title="Operating loss carryforwards description"><ix:nonNumeric contextRef="From2022-10-012023-09-30_custom_FederalMember" name="avxl:OperatingLossCarryforwardsDescription">$37.7 million will begin to expire in 2025 and $88.6 million can be carried forward indefinitely</ix:nonNumeric></span>, state and local net operating
loss carryforwards of approximately $ <span id="xdx_90C_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20230930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--StateAndLocalJurisdictionMember_znWgRNUdAPJi" title="Operating loss carryforwards"><ix:nonFraction name="us-gaap:OperatingLossCarryforwards" contextRef="AsOf2023-09-30_us-gaap_StateAndLocalJurisdictionMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">16.6</ix:nonFraction></span> million (2022: $<span id="xdx_903_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20220930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--StateAndLocalJurisdictionMember_zkKt1osnqZF" title="Operating loss carryforwards"><ix:nonFraction name="us-gaap:OperatingLossCarryforwards" contextRef="AsOf2022-09-30_us-gaap_StateAndLocalJurisdictionMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">17.2</ix:nonFraction></span> million) which will begin to expire in <span id="xdx_900_ecustom--OperatingLossCarryForwardsExpirationYear_c20221001__20230930_zdJ60uniXWnf" title="Operating loss carry forwards expiration year"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="avxl:OperatingLossCarryForwardsExpirationYear">2036</ix:nonNumeric></span>, and Research and Development
tax credits of approximately $<span id="xdx_90E_eus-gaap--IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment_pn5n6_c20221001__20230930_zQ2xyYUFqcF4" title="Research and Development tax credits"><ix:nonFraction name="us-gaap:IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment" contextRef="From2022-10-01to2023-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">2.7</ix:nonFraction></span> million (2022: $<span id="xdx_90E_eus-gaap--IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment_pn5n6_c20211001__20220930_zwbv1IZxF4yf" title="Research and Development tax credits"><ix:nonFraction name="us-gaap:IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment" contextRef="From2021-10-012022-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">2.2</ix:nonFraction></span> million) which will begin to expire in <span id="xdx_901_ecustom--ResearchAndDevelopmentTaxCreditsYear_c20221001__20230930_z37rCamF6FZf" title="Research and development tax credits year"><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" name="avxl:ResearchAndDevelopmentTaxCreditsYear">2029</ix:nonNumeric></span>. The Company had approximately $<span id="xdx_908_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20230930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--ForeignCountryMember_zqR1kpkjOcZi" title="Operating loss carryforwards"><ix:nonFraction name="us-gaap:OperatingLossCarryforwards" contextRef="AsOf2023-09-30_us-gaap_ForeignCountryMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">12.9</ix:nonFraction></span>
million (approximately AU$<span id="xdx_90C_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20230930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--ForeignCountryMember__srt--CurrencyAxis__currency--AUD_ztNLboBVPHeh" title="Operating loss carryforwards"><ix:nonFraction name="us-gaap:OperatingLossCarryforwards" contextRef="AsOf2023-09-30_us-gaap_ForeignCountryMember_currency_AUD" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">20.1</ix:nonFraction></span> million) (2022: $<span id="xdx_909_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20220930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--ForeignCountryMember_ziNKvWRETWKa" title="Operating loss carryforwards"><ix:nonFraction name="us-gaap:OperatingLossCarryforwards" contextRef="AsOf2022-09-30_us-gaap_ForeignCountryMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">10.6</ix:nonFraction></span> million (approximately AU$ <span id="xdx_90A_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20220930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--ForeignCountryMember__srt--CurrencyAxis__currency--AUD_zPtmb3CPEkbk" title="Operating loss carryforwards"><ix:nonFraction name="us-gaap:OperatingLossCarryforwards" contextRef="AsOf2022-09-30_us-gaap_ForeignCountryMember_currency_AUD" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">14.9</ix:nonFraction></span> million)) of net operating loss carryforwards in
Australia, which have an indefinite life, available to offset future taxable income in those jurisdictions.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company evaluates its valuation allowance requirements based on available evidence. When circumstances change, and this causes a change
in management&#8217;s judgment about the recoverability of deferred tax assets, the impact of the change on the valuation allowance is
reflected in current income. Because management of the Company does not currently believe that it is more likely than not that the Company
will receive the benefit of these assets, a valuation allowance has been established at September 30, 2023 and 2022.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Tax Cuts and Jobs Act of 2017 (TCJA) has modified the IRC 174 expenses related to research and development for tax years beginning after
December 31, 2021. Under the TCJA, the Company must now capitalize the expenditures related to research and development activities and
amortize over five years for U.S. activities and 15 years for non-U.S. activities using a mid-year convention. Therefore, the capitalization
of research and development costs in accordance with IRC 174 resulted in a gross deferred tax asset of $<span id="xdx_902_eus-gaap--DeferredTaxAssetsGross_iI_pn5n6_c20230930_z5Huz0MUkYf6" title="Gross deferred tax asset"><ix:nonFraction name="us-gaap:DeferredTaxAssetsGross" contextRef="AsOf2023-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">7.2</ix:nonFraction></span> million.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Uncertain
Tax Positions</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company files income tax returns in the U.S. federal jurisdiction and various state and local and foreign jurisdictions. The Company&#8217;s
tax returns are subject to tax examinations by U.S. federal and state tax authorities, or examinations by foreign tax authorities until
the respective statutes of limitation expire. The Company is subject to tax examinations by tax authorities for all taxation years commencing
on or after 2005.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Under
the provisions of the Internal Revenue Code, the net operating loss (&#8220;NOL&#8221;) carryforwards are subject to review and possible
adjustment by the Internal Revenue Service and state tax authorities. Under Section 382 of the Internal Revenue Code, NOL and tax credit
carryforwards may become subject to an annual limitation in the event of an over 50% cumulative change in the ownership interest of significant
stockholders over a three-year period, as well as similar state tax provisions.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company conducted a Section 382 study during the year ended September 30, 2021 and determined that, during the year ended September 30,
2015, there was a change in ownership which resulted in $<span id="xdx_901_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20150930__us-gaap--IncomeTaxAuthorityAxis__custom--FederalMember_zuBVmpmXLoCf" title="Operating loss carryforwards"><ix:nonFraction name="us-gaap:OperatingLossCarryforwards" contextRef="AsOf2015-09-30_custom_FederalMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">25.8</ix:nonFraction></span> million of federal NOLs being subject to an annual limitation. During the
year ended September 30, 2021, the Company reduced its federal NOLs by $<span id="xdx_909_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20210930__us-gaap--IncomeTaxAuthorityAxis__custom--FederalMember_zoCzhr2kvOkb" title="Operating loss carryforwards"><ix:nonFraction name="us-gaap:OperatingLossCarryforwards" contextRef="AsOf2021-09-30_custom_FederalMember" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">12.1</ix:nonFraction></span> million and its Research and Development tax credit carryforwards
by $<span id="xdx_90F_eus-gaap--DeferredTaxAssetsTaxCreditCarryforwardsResearch_iI_pn5n6_c20210930_zkOU6AbJlz5e" title="Research and development tax credit carryforwards"><ix:nonFraction name="us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch" contextRef="AsOf2021-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">0.8</ix:nonFraction></span> million, which are the amount of tax assets that will expire unutilized pursuant to the Section 382 study. This resulted in a
reduction of $<span id="xdx_90C_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20210930_zkk8l6wnAZm9" title="Operating loss carryforwards"><ix:nonFraction name="us-gaap:OperatingLossCarryforwards" contextRef="AsOf2021-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">2.5</ix:nonFraction></span> million of NOLs and $<span id="xdx_90F_eus-gaap--DeferredTaxAssetsTaxCreditCarryforwardsResearch_iI_pn5n6_c20210930_zugz7EAgAHc8" title="Research and development tax credit carryforwards"><ix:nonFraction name="us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch" contextRef="AsOf2021-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">0.8</ix:nonFraction></span> million of research and development credits and a corresponding reduction in the valuation
allowance of $<span id="xdx_901_eus-gaap--ValuationAllowanceDeferredTaxAssetChangeInAmount_pn5n6_c20201001__20210930_zAPCM1FPnLya" title="Decrease in valuation allowance"><ix:nonFraction name="us-gaap:ValuationAllowanceDeferredTaxAssetChangeInAmount" contextRef="From2020-10-012021-09-30" format="ixt:numdotdecimal" decimals="-5" scale="6" unitRef="USD">3.3</ix:nonFraction></span> million, which was recorded in the 2021 fiscal year. Subsequent ownership changes in future years could trigger additional
limitations of the Company&#8217;s NOLs<span style="background-color: white">. During the year ended September 30, 2023 and 2022 the
Company determined that there were no changes in ownership pursuant to Section 382.</span></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">As
of September 30, 2023, the Company did not provide any foreign withholding taxes related to its foreign subsidiaries&#8217; undistributed
earnings, as such earnings have been retained and are intended to be indefinitely reinvested to fund ongoing operations of the foreign
subsidiaries. It is not practicable to estimate the amount of taxes that would be payable upon remittance of these earnings, because
such tax, if any, is dependent upon circumstances existing if and when remittance occur.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><ix:nonNumeric contextRef="From2022-10-01to2023-09-30" escape="true" name="us-gaap:SubsequentEventsTextBlock"><p id="xdx_803_eus-gaap--SubsequentEventsTextBlock_z3bCaqjnWyw5" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
8&#9;<span id="xdx_827_z2tGny4WyLe6">Subsequent Events</span></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company evaluates subsequent events occurring between the most recent balance sheet date and the date the financial statements are available
to be issued in order to determine whether the subsequent events are to be recorded and/or disclosed in the Company&#8217;s financial
statements and footnotes. The financial statements are considered to be available to be issued at the time they are filed with the Securities
and Exchange Commission (SEC).</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">There
were no subsequent events or transactions that required recognition or disclosure in the consolidated financial statements.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

</ix:nonNumeric><p id="xdx_813_zBosptepty7e" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span>&#160;</p>

<p style="margin: 0"></p>



<p style="margin: 0"></p>




<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><b></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"></p>

<!-- Field: Page; Sequence: 89; Value: 1 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 6pt; margin-bottom: 6pt"><p style="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&#160;F-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->22<!-- Field: /Sequence --></p></div>
    <div style="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><p style="margin: 0pt">&#160;</p></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_013"></span>ITEM 9. CHANGES
IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND FINANCIAL MATTERS </span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Not Applicable</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_014"></span>ITEM 9A. CONTROLS
AND PROCEDURES</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Disclosure Controls and Procedures</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We maintain disclosure controls and procedures
that are designed to provide reasonable assurance that material information required to be disclosed in our periodic reports filed
under the Exchange Act is recorded, processed, summarized, and reported within the time periods specified in the SEC&#8217;s rules
and forms and to provide reasonable assurance that such information is accumulated and communicated to our management, our chief
executive officer and our principal financial officer, to allow timely decisions regarding required disclosure.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We carried out an evaluation, under the supervision
and with the participation of our management, including our principal executive and principal financial officer, of the effectiveness
of the design and operation of our disclosure controls and procedures, as defined in&#160;Rule&#160;13(a)-15(e) under the Exchange
Act. Based on this evaluation, our principal executive officer and principal financial officer concluded that our disclosure controls
and procedures were effective as of September 30, 2023.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Management&#8217;s Annual Report on Internal
Control over Financial Reporting </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Our management is responsible for establishing
and maintaining adequate internal control over financial reporting as defined in Rules&#160;13a-15(f) and 15d-15(f) under the Exchange
Act. Under the supervision and with the participation of our management, including our Principal Executive Officer and Principal
Financial Officer, we conducted an evaluation of the effectiveness of our internal control over financial reporting based on criteria
established in the framework in&#160;Internal Control &#8212; Integrated Framework (2013) issued by the Committee of Sponsoring
Organizations of the Treadway Commission (&#8220;COSO&#8221;).</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Because of its inherent limitations,
internal control over financial reporting may not prevent or detect misstatements. Also, projections of any evaluation of effectiveness
to future periods are subject to the risks that controls may become inadequate because of changes in conditions, or that the degree
of compliance with the policies or procedures may deteriorate.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Based on this evaluation, our management
concluded that our internal controls over financial reporting were effective as of September 30, 2023.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The effectiveness of our internal control over
financial reporting as of September 30, 2023, has been audited by Grant Thornton LLP, an independent registered public accounting
firm, as stated in their report which appears in this Annual Report on Form 10-K.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Changes in Internal Control over Financial
Reporting</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">During the quarter ended September 30,
2023, there were no material changes in our internal control over financial reporting identified in management&#8217;s evaluation
pursuant to Rules 13a 15(d) or 15d 15(d) of the Exchange Act that materially affected, or are reasonably likely to materially affect,
our internal controls over financial reporting.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 90; Options: NewSection; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->69<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_015"></span>ITEM 9B OTHER
INFORMATION</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">None.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_016"></span>ITEM 9C DISCLOSURE
REGARDING FOREIGN JURISDICTIONS THAT PREVENT INSPECTIONS</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Not applicable.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span id="a_017"></span>PART III</p>

<p style="font: bold 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_018"></span>ITEM 10 DIRECTORS,
EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Directors and Executive Officers</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Our directors are to be elected at our
annual meeting and each director elected is to hold office until his or her successor is elected and qualified. Our Board of Directors
may remove our officers at any time.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Our directors and executive officers,
their ages, positions held, and duration of such, are as follows:</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <tr style="vertical-align: top">
    <td style="width: 25%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Name</b></span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 32%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Position</b></span></td>
    <td style="text-align: center; width: 10%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Age</b></span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 31%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Date first appointed</b></span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Christopher Missling, PhD</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director, President, Chief</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">58</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">July 5, 2013</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Executive Officer, Secretary</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Jiong Ma, PhD</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director, Chair</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">59</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">May 25, 2021</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Athanasios Skarpelos</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">56</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">January 9, 2013</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Claus van der Velden, PhD</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">51</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">March 2, 2018</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Steffen Thomas, PhD</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">57</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">June 15, 2015</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Peter Donhauser, D.O.</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">58</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">February 8, 2017</span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Sandra Boenisch, CPA, CGA</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Principal Financial Officer,</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">42</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">October 1, 2015</span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Treasurer</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  </table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;<b><i>&#160;</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Board Leadership Structure</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Board of Directors is composed of
a majority of independent directors and the Chief Executive Officer of the Company.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Our Board of Directors has appointed
an independent Board Chair, Dr. Jiong Ma. As Board Chair, Dr. Ma has the authority, among other things, to call and preside over
meetings of our Board, to set meeting agendas, and to determine materials to be distributed to the Board. The Company believes
separation of the positions of Board Chair and Chief Executive Officer reinforces the independence of our Board in its oversight
of the business and affairs of the Company. In addition, the Company believes that having an independent Board Chair creates an
environment that is more conducive to objective evaluation and oversight of management&#8217;s performance, increasing management
accountability and improving the ability of our Board to monitor whether management&#8217;s actions are in the best interests of
the Company and its stockholders.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Audit Committee, Compensation Committee,
and Nominating and Corporate Governance Committee each have oversight over specific areas of responsibility, as discussed further
below.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 91; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->70<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Board of Directors&#8217; Role in Risk
Oversight</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Board of Directors is responsible
for oversight of the Company&#8217;s risk management process. The Board administers this oversight function directly through the
Board of Directors as a whole, as well as through the committees of the board. Areas of focus include economic risk, operational
risk, financial risk (accounting, investment or liquidity, and tax), competitive risk, legal and regulatory risk, cybersecurity
risk and compliance and reputational risks. The Board of Directors is supported by regular reporting by management, which is designed
to give the Board of Directors visibility over the Company&#8217;s operations and activities to adequately identify key risks and
understand management&#8217;s risk mitigation strategies.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Business Experience</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The following is a brief account of
the education and business experience of directors and executive officers during at least the past five years, indicating their
principal occupations during the period, and the names and principal businesses of the organizations by which they were employed.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="text-decoration: underline">Christopher Missling, PhD</span>. Christopher
Missling has over twenty years of healthcare industry experience in big pharmaceutical, biotech and investment banking. Most recently,
from March 2007 until his appointment by our Company, Dr. Missling served as the head of healthcare investment banking at Brimberg
&amp; Co. in New York, New York. In addition, Dr. Missling served as the Chief Financial Officer of Curis, Inc. (NASDAQ:CRIS) and
ImmunoGen, Inc. (NASDAQ:IMGN). Dr. Missling earned his MS and PhD from the University of Munich and an MBA from Northwestern University
Kellogg School of Management and WHU Otto Beisheim School of Management.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="text-decoration: underline">Jiong Ma, PhD.</span> Jiong Ma has over 25
years of experience in the investing, building and scaling of companies with a focus on innovative product launches in digital
health, technology and the new energy transition. Dr. Ma currently serves on the board of SES AI Corporation (NYSE: SES), and LinkinVax,
a biotech company, spin-off from the Vaccine Research Institute in France. Dr. Ma served as senior partner and a member of the
investment committee at Braemar Energy Ventures (&#8220;Braemar&#8221;). While at Braemar, Dr. Ma led investments in more than
15 companies involved in either resource efficiency, e-mobility, industrial digitalization, renewable energy, or deep tech, and
has achieved multiple successful exits through M&amp;A and IPO. Dr. Ma has significant knowledge and expertise in the technology
industry, including information security. Prior to Braemar Energy Ventures, she was with the Venture Capital Group at 3i Group,
a global private equity firm, where she led investments across multiple stages in Digital Health, TMT and Cleantech. Preceding
the Venture Capital Group at 3i, Dr. Ma held several senior positions at Lucent Technologies and Bell Labs. Her responsibilities
included lead roles in product portfolio strategy, new product launches for Optical and Data Networking, and research and product
development. Dr. Ma was also a founding team member of Onetta Inc., a fiber networks company. She has a PhD in Electrical and Computer
Engineering from the University Colorado at Boulder and an MS in Electrical Engineering from Worcester Polytechnic Institute. Dr.
Ma is a Kauffman Fellow.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="text-decoration: underline">Athanasios Skarpelos</span>. Athanasios
(Tom) Skarpelos is a self-employed investor with 20 years of experience working with private and public companies with a focus
on biotechnology companies involved in drug discovery and drug development projects. His experience has led to relationships with
researchers at academic institutes in Europe and North America. Mr. Skarpelos is a founder of Anavex.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="text-decoration: underline">Claus van der Velden, PhD</span>. Claus
van der Velden, PhD, brings significant expertise in management, accounting, internal controls, information security and risk management.
Since May 2021, he has served as <span style="background-color: white">Managing Director (Chief Financial Officer) of NetCologne
GmbH, a regional telecommunication provider in Germany</span>. From July 2011 to May 2021, he served as corporate head of Management
Accounting, Internal Audit and Risk Management at Stroeer SE &amp; Co KGaA, a publicly listed German digital media company. Previously,
Dr. van der Velden served as the Director of Corporate Business Controlling for the Nutrition &amp; Health business unit at Cognis,
a worldwide supplier of global nutritional ingredients and specialty chemicals. In this position, he was also a compliance representative
and a member of the global leadership team. After the acquisition of Cognis by BASF, he was responsible for the management accounting
processes of the BASF Nutrition &amp; Health division, developing and producing mostly natural-source ingredients for the food
and healthcare industries. Dr. van der Velden started his career as a strategy consultant at an international marketing and strategy
consultancy firm. He studied in Kiel and Stockholm and received a degree in economics from the University of Kiel and later obtained
his doctorate in business management from the WHU-Otto Beisheim School of Management where he also previously taught economics.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 92; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->71<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="text-decoration: underline">Steffen Thomas, PhD</span>. Steffen
Thomas, has over 15 years of experience as a European patent attorney and is currently practicing at Epping Hermann Fischer, a
major intellectual property law firm in Europe. Previously, he worked for Japan-based Takeda Pharmaceutical Company, the largest
pharmaceutical company in Asia and a top firm worldwide, as an in-house patent attorney. Prior to that, he worked for Nycomed Pharma,
acquired by Takeda in 2011 for approximately USD $10 billion. Dr. Thomas&#8217; legal practice covers drafting of patent applications,
prosecuting patent applications before national and international patent offices, defending and challenging patents in opposition,
appeal, and nullity proceedings, enforcing patents before the infringement courts, and preparing opinions on patentability and
infringement in the technical field of chemistry. Dr. Thomas has particular expertise in small molecule pharmaceuticals. He holds
MS and PhD degrees in Chemistry from the University of Munich.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="text-decoration: underline">Peter Donhauser, D.O.</span> Peter Donhauser,
had more than 20 years of expertise in clinical research prior to practicing osteopathic medicine with an integrated medical approach
in private practice beginning in 2000. He worked at the University Hospital of Munich in the fields of geriatrics and neuromusculoskeletal
diseases. During this time, he was a clinical trial investigator in multiple Phase 3 studies, including studies sponsored by Merck
Sharp &amp; Dohme, Merck, Boehringer Mannheim, Roche, Servier and Sanofi. He received his human medicine degree at the University
of Munich and Doctor of Osteopathic Medicine (D.O.) from the German-American Academy for Osteopathy, or DAAO, a member of the European
Register for Osteopathic Physicians, or EROP, at the Philadelphia College of Osteopathic Medicine.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="text-decoration: underline">Sandra Boenisch, CPA, CGA.</span> Ms.
Boenisch is a Chartered Professional Accountant (CPA, CGA) with approximately 20 years of accounting, audit and financial reporting
experience in a variety of industries, both in the United States and Canada. Ms. Boenisch was an independent consultant, providing
financial reporting services to a range of public companies in the United States and Canada since January 2012. From 2008 until
2012, Ms. Boenisch was employed at BDO Canada LLP (Vancouver, BC) where she was hired as a Senior Accountant and was later promoted
to Manager, Audit Assurance. Ms. Boenisch specialized in managing assurance engagements for public companies in the United States
and Canada. Prior to that, Ms. Boenisch worked for another public accounting firm from 2001 to 2008. As an independent consultant,
Ms. Boenisch has acquired considerable experience in finance, governance, and regulatory compliance. She holds a BComm from Laurentian
University.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Family Relationships</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">There are no family relationships between
any director or executive officer.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Involvement in Certain Legal Proceedings</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">There are no material proceedings to
which any director or executive officer or any associate of any such director or officer is a party adverse to our Company or has
a material interest adverse to our Company.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Delinquent Section 16(a) Reports </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">None.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Business Code of Conduct &amp; Ethics</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">We have adopted a code of conduct and
ethics that applies to our directors, principal executive officer, principal financial officer, principal accounting officer or
controller, or persons performing similar functions, and to all employees. We have posted our policy on our website at www.anavex.com/code-of-conduct.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 93; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->72<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Insider Trading Policy</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Our Insider Trading Policy prohibits
our directors, officers, employees and consultants from engaging in short sales, transactions in publicly traded options such as
put, calls or other derivative securities, hedging transactions and other inherently speculative transactions with respect to our
stock at any time. Our policy further prohibits such persons from engaging in transactions involving any loan, pledge or other
transfer of beneficial ownership of the Company&#8217;s securities without obtaining advance clearance of the proposed transaction
from our Insider Trading Compliance Officer.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Information Regarding Committees of the
Board of Directors</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Board has an Audit Committee, a
Compensation Committee and a Nominating and Corporate Governance Committee. The following table provides membership and meeting
information for 2023:</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
    <td style="border-bottom: Black 1pt solid; font-weight: bold; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Name</span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">Audit
    Committee</span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">Compensation
    Committee</span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">Nominating
    and Corporate Governance Committee</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Christopher
    Missling, PhD</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Athanasios
    Skarpelos</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">X</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Claus
    van der Velden, PhD</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">X*</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">X*</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">X*</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Steffen
    Thomas, PhD</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">X</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">X</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">X</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Peter
    Donhauser, D.O.</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">X</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">X</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Jiong
    Ma, PhD</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">X</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="width: 46%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Meetings
    in 2023</span></td><td style="width: 5%; padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; width: 1%; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; width: 11%; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">4</span></td><td style="width: 1%; padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 5%; padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; width: 1%; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; width: 11%; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">1</span></td><td style="width: 1%; padding-bottom: 1pt; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 5%; padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; width: 1%; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="border-bottom: Black 1pt solid; width: 11%; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="width: 1%; padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif">&#160;</span></td></tr>
</table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">*Committee Chair</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Audit Committee and Audit Committee Financial
Experts </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Audit Committee is composed of four
directors, each of whom is independent. The Audit Committee operates under a charter that was adopted by our Board of Directors.
The Audit Committee oversees and reports to our Board of Directors on various auditing and accounting-related matters, including,
among other things, the maintenance of the integrity of our financial statements, reporting process and internal controls; the
selection, evaluation, compensation and retention of our independent registered public accounting firm; legal and regulatory compliance,
including our disclosure controls and procedures; and oversight over our risk management policies and procedures.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Our Board of Directors has determined
that Claus van der Velden is an &#8220;audit committee financial expert&#8221; as defined by applicable SEC and NASDAQ rules.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Audit Committee has reviewed and
discussed the audited consolidated financial statements with management.<span style="background-color: white"> </span>The Audit
Committee has discussed with the Company&#8217;s independent registered public accounting firm the matters required to be discussed
by the applicable requirements of the Public Company Accounting Oversight Board (&#8220;PCAOB&#8221;) and the Securities and Exchange
Commission (the &#8220;SEC&#8221;). In addition, the Audit Committee has received the written disclosures and the letter from the
independent registered public accounting firm required by applicable requirements of the PCAOB regarding the firm&#8217;s communications
with the Audit Committee concerning independence and has discussed with the independent registered accounting firm its independence
from the Company and management. Based on the reviews and discussions referred to above, the Audit Committee recommended to the
Board that the audited consolidated financial statements for the Company for the fiscal year ended September 30, 2023 be included
in this Annual Report on Form 10-K for the year ended September 30, 2023.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: right">The foregoing report has been furnished
by the Audit Committee.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: right">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: right">Claus van der Velden (Chairman)<br />
Athanasios Skarpelos<br />
Steffen Thomas<br />
Jiong Ma</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: right">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: right"></p>

<!-- Field: Page; Sequence: 94; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->73<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: right">&#160;&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><b><i>Compensation Committee</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><b>&#160;</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Compensation Committee is composed
of three directors, each of whom is independent. The Compensation Committee operates under a charter that was adopted by our Board
of Directors. The Compensation Committee assists our Board of Directors in discharging its responsibilities relating to compensation
of our directors and executive officers. Its responsibilities include, among other things: reviewing, approving and recommending
compensation programs and arrangements applicable to our officers; determining the objectives of our executive officer compensation
programs; overseeing the evaluation of our senior executives; administering our incentive compensation plans and equity-based plans,
including reviewing and granting equity awards to our executive officers; and reviewing and approving director compensation and
benefits. The Compensation Committee can delegate to other members of our Board of Directors, or an officer or officers of the
Company, the authority to review and grant stock-based compensation for employees who are not executive officers.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Compensation Committee has the responsibilities
and authority designated by NASDAQ rules and the Compensation Committee Charter. Specifically, the Compensation Committee has the
sole discretion to select and receive advice from a compensation consultant, legal counsel or other adviser and is directly responsible
for oversight of their work. The Compensation Committee must also determine reasonable compensation to be paid to such advisors
by us.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Compensation Committee met one time
during fiscal 2023 and acted by written consent as required.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Nominating and Corporate Governance
Committee</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Nominating and Corporate Governance
Committee (the &#8220;NCG Committee&#8221;) is appointed by the board to oversee and evaluate the Board&#8217;s performance and
the Company&#8217;s compliance with corporate governance regulations, guidelines and principles, to identify individuals qualified
to become Board members, to recommend to the Board proposed nominees for board membership, and to recommend to the Board directors
to serve on each standing committee. The NCG Committee seeks to assemble a Board that possesses the appropriate balance of professional
and industry knowledge, financial expertise and management experience that is necessary to oversee the Company&#8217;s business.
The NCG also recognizes the importance of diversity in board composition, including diversity of experience, gender and ethnicity
and seeks to continually strive towards optimal diversity. The NCG Committee operates under a charter that was adopted by our Board
of Directors.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The NCG Committee did not meet during
fiscal 2023 but acted by written consent as required.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_019"></span>ITEM 11. EXECUTIVE
COMPENSATION</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Company&#8217;s compensation objectives
are to offer our executive officers&#8217; compensation and benefits that are competitive and meet our goals of attracting, retaining
and motivating highly skilled, talented management, which is necessary for the Company to achieve its financial and strategic objectives
and create long-term value for our stockholders.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">A significant portion of the Company&#8217;s
executive compensation opportunity is related to factors that directly and indirectly influence shareholder value, including long-term
stock performance and operational performance. We believe the levels of compensation we provide should be competitive, reasonable
and appropriate for our business needs and circumstances.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Our Executive Compensation Program
and Philosophy</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The intent of the Company&#8217;s compensation
program is to attract and retain talent, to create incentives for and to reward excellent performance. We seek to compensate our
executives in a manner that is competitive, rewards performance that creates shareholder value, recognizes individual contributions,
and encourages long-term value creation.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 95; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->74<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Compensation Committee meets at
least once per year to review and evaluate executive compensation and each executive officer&#8217;s performance. The Compensation
Committee utilizes quantitative and qualitative factors, including the accomplishment of initiatives, attitude, and leadership
and applies overall judgment to assess performance, taking into account the financial condition of the Company. In setting compensation,
the Compensation Committee considers the outcome of the most recent say-on-pay vote, as well as stockholder feedback throughout
the year, when making compensation decisions for our executive officers. In our most recent say-on-pay vote, conducted at our 2021
annual meeting of stockholders, held on May 25, 2021, our stockholders approved the compensation of our named executive officers
on an advisory basis, with 88% of the votes cast in favor of the fiscal 2021 compensation of our named executive officers. Ultimately,
the Compensation Committee seeks to evaluate, based on the achievement of financial and nonfinancial objectives, the variable compensation,
including special awards, of executive officers of the Company and decide on the base salary and target discretionary bonus for
such persons taking into account relevant benchmark data.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Compensation Committee believes
that a significant portion of each executive&#8217;s compensation opportunity should be tied to variable compensation and value
creation for shareholders. The Compensation Committee believes this mix provides an appropriate balance between the financial security
required to attract and retain qualified individuals, and the Compensation Committee&#8217;s goal of ensuring that executive compensation
rewards performance that benefits shareholders over the long term.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Compensation Risk Oversight </i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">In administering our compensation program,
the Compensation Committee strives to achieve a balance among the elements of compensation to accomplish the objectives of the
program. The Compensation Committee reviews the Company&#8217;s overall compensation program in the context of the risks that may
be presented by the structure of our compensation program and the metrics used to determine compensation under that program. Based
upon this review, the Compensation Committee believes that our compensation program does not create a reasonable likelihood of
a material adverse effect on the Company.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Compensation Consultants</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Compensation Committee makes recommendations
to the Board for all compensation for executives, including the structure and design of the compensation programs. The Compensation
Committee is responsible for retaining and terminating compensation consultants and determining the terms and conditions of their
engagement. During fiscal 2023, the Compensation Committee did not engage any compensation consultants.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Elements of Executive Compensation</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">We focus our executive compensation
program on three related but distinct elements: base salary, cash bonuses and stock-related compensation.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Base Salary</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Base salaries take into consideration
a number of factors, including the executive&#8217;s job performance, our corporate performance, and compensation practices observed
in the market.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Annual Discretionary Cash Bonuses</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Company has an annual discretionary
cash bonus program. We provide such bonuses to motivate executive officers to perform on behalf of general corporate goals and
to perform in their areas of responsibility. The Compensation Committee, or Board of Directors, works with the Chief Executive
Officer to evaluate the Company&#8217;s financial performance and overall financial condition to determine if discretionary bonuses
are to be paid.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 96; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->75<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Equity Compensation </i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Equity compensation includes stock option
grants within the terms of our 2022 Omnibus Incentive Plan. Each executive officer is eligible for stock option grants under the
Omnibus Incentive Plans which may vest over a required service period, &#8220;Time Based Awards&#8221;, or that vest upon achievement
of certain performance criteria, &#8220;Performance Awards&#8221;. Generally, our Compensation Committee grants Time Based Awards
at or near the date of hire. Such grants are intended to link executive compensation with stockholder value over time. Subsequent
awards are granted as Performance Awards, which are intended to align executive compensation with the company&#8217;s short-term
and long-term objectives. Our compensation committee selects performance goals that reflect the company&#8217;s short-term and
longer-term objectives to ensure executives, as well as all employees, are rewarded for the successful and timely accomplishment
of these objectives. Generally, these performance criteria include milestones in connection with the successful execution, enrollment
and completion of the Company&#8217;s clinical trials. Only our Board of Directors, acting in its sole discretion, or the Compensation
Committee grants options or Performance Awards to our executive officers.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">We view stock options as one of the
more important components of our long-term, performance-based compensation philosophy.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">We provide options through initial grants
at or near the date of hire and subsequent periodic/annual grants. Generally, initial option grants vest over a three-year period
and have an exercise price equal to the fair market value of our stock at the time of grant. Initial grant amounts are based on
ranges that take into consideration an executive&#8217;s job responsibilities and competitive market data.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">We grant periodic additional stock options
to reflect the individual&#8217;s ongoing contributions to the long-term success and growth of the Company, to incentivize individuals
to remain with the Company and to provide a long-term incentive to achieve or exceed our corporate goals. We do not have a program,
plan or practice to time stock option grants to our executives in coordination with the release of material nonpublic information.
We have not re-priced any of our options and do not intend to re-price or otherwise adjust outstanding options at any time in the
future.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Other Compensation</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Other components of compensation include
employee medical benefit plans and 401(k) benefit plan contributions.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>Employee Medical Benefit Plans.</b>
Our employee medical and welfare benefit plans include medical, dental, life, disability and accidental death&#160;and dismemberment
insurance.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Tahoma, Helvetica, Sans-Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>401(k) Plan.</b> We have a defined-contribution
savings plan under Section 401(k) of the Internal Revenue Code. The plan covers all United States based employees. United States
based employees eligible to participate in the plan may contribute up to the current statutory limits under the Internal Revenue
Service regulations. The 401(k) plan permits the Company to make additional matching contributions on behalf of contributing employees.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Compensation Committee Interlocks
and Insider Participation</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0.7pt 0 0; text-align: justify"><span style="font-family: Tahoma, Helvetica, Sans-Serif"><b>&#65279;</b></span><span style="font-family: Times New Roman, Times, Serif">No
member of the Compensation Committee has ever been an officer or employee of the Company.&#160;None of the executive officers currently
serves or has served on the Compensation Committee or board of directors of any other entity that has one or more executive officers
serving as a member of the Board of Directors or Compensation Committee of the Company.</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0.7pt 0 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0.7pt 0 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 97; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->76<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0.7pt 0 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0.7pt 0 0; text-align: justify"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>Managing Compensation-Related Risks</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Although a portion of the compensation
provided to our executive officers and other employees is performance-based, the executive compensation program does not encourage
excessive or unnecessary risk taking. This is primarily due to the fact that the compensation program is designed to encourage
executive officers and other employees to remain focused on both short-term and long-term strategic goals within the context of
our pay-for-performance compensation philosophy.<span style="background-color: white"> </span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="background-color: white">&#160;</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; background-color: white"><b><i>Clawback Policy</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; background-color: white">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">In November
2023, the Board of Directors adopted an executive officer compensation clawback policy that may be applied in the event of a material
financial restatement. The clawback policy covers all of the named executive officers and includes all incentive-based compensation.
Specifically, in the event of an accounting restatement, the Company must recover, reasonably promptly, erroneously awarded compensation
in amounts determined pursuant to the policy. Compensation that may be recoverable under the policy includes cash or equity-based
compensation for which the grant, payment or vesting (or any portion thereof) is or was predicated upon the achievement of specified
financial results that are impacted by the material financial restatement, and the amount of compensation that may be impacted
by the clawback policy is the difference between the amount paid or granted, and the amount that should have been paid or granted,
if calculated on the updated financials. Recovery under the policy with respect to an executive officer will not require the finding
of any misconduct by such executive officer or such executive officer being found responsible for the accounting error leading
to an accounting restatement.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Compensation Committee Report</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0.7pt 0 0; text-align: justify">The Compensation Committee
has reviewed and discussed with management the Compensation Discussion and Analysis contained in this Annual Report on Form 10-K.
Based on this review and discussion, the Compensation Committee has recommended to the Board of Directors that the Compensation
Discussion and Analysis be included in this Annual Report on Form 10-K for the fiscal year ended September 30, 2023.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0.7pt 0 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0.7pt 0 0; text-align: right">The foregoing report has been
furnished by the Compensation Committee.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0.7pt 0 0; text-align: right">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0.7pt 0 0; text-align: right">Claus van der Velden, Committee
Chair&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0.7pt 0 0; text-align: right">Steffen Thomas&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0.7pt 0 0; text-align: right">Peter Donhauser</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0.7pt 0 0; text-align: right">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Summary Compensation </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The particulars of compensation paid
to our named executive officers for the last two completed fiscal years:</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
  <tr style="vertical-align: bottom">
  <td style="border-bottom: Black 1pt solid; padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><b>Name
  and Principal Position</b></td>
  <td style="padding-bottom: 1pt; font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;
  &#160; &#160; &#160;</b></span></td>
  <td colspan="3" style="border-bottom: Black 1pt solid; font-size: 10pt; text-align: center"><b>Year</b></td>
  <td style="padding-bottom: 1pt; font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;
  &#160; &#160; &#160;</b></span></td>
  <td colspan="3" style="border-bottom: Black 1pt solid; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Salary<br />
($)</b></span></td>
  <td style="padding-bottom: 1pt; font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;
  &#160; &#160; &#160;</b></span></td>
  <td colspan="3" style="border-bottom: Black 1pt solid; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Bonus<br />
($)</b></span></td>
  <td style="padding-bottom: 1pt; font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;
  &#160; &#160; &#160;</b></span></td>
  <td colspan="3" style="border-bottom: Black 1pt solid; font-size: 10pt; text-align: center"><b>Option <span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Awards<br />
($)</span></b></td>
  <td style="font: bold 10pt Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;
  &#160; &#160; &#160;</b></span></td>
  <td colspan="3" style="border-bottom: Black 1pt solid; font: bold 10pt Times New Roman, Times, Serif; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>All
  other Compensation<br />
($)<sup>(1)</sup></b></span></td>
  <td style="padding-bottom: 1pt; font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;
  &#160; &#160; &#160;</b></span></td>
  <td colspan="3" style="border-bottom: Black 1pt solid; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Total<br />
($)</b></span></td>
</tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; width: 40%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Christopher Missling,
    PhD</span></td><td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 6%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td><td style="width: 1%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 6%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">700,000</span></td><td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 6%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">124,753</span></td><td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 6%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3,066,200</span></td><td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 6%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3,500</span></td><td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 6%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3,894,453</span></td><td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 20pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">President, Chief Executive
    Officer,</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td><td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">586,400</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">110,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6,045,043</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">12,200</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6,753,643</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding-top: 0pt; padding-right: 0pt; padding-left: 20pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">and Director</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td><td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">550,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">110,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">8,745,457</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">11,600</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,417,057</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding-top: 0pt; padding-right: 0pt; padding-left: 20pt; text-align: left; text-indent: -10pt">&#160;</td><td>&#160;</td>
    <td style="text-align: center">&#160;</td><td style="text-align: center">&#160;</td><td style="text-align: center">&#160;</td><td>&#160;</td>
    <td style="text-align: left">&#160;</td><td style="text-align: right">&#160;</td><td style="text-align: left">&#160;</td><td>&#160;</td>
    <td style="text-align: left">&#160;</td><td style="text-align: right">&#160;</td><td style="text-align: left">&#160;</td><td>&#160;</td>
    <td style="text-align: left">&#160;</td><td style="text-align: right">&#160;</td><td style="text-align: left">&#160;</td><td>&#160;</td>
    <td style="text-align: left">&#160;</td><td style="text-align: right">&#160;</td><td style="text-align: left">&#160;</td><td>&#160;</td>
    <td style="text-align: left">&#160;</td><td style="text-align: right">&#160;</td><td style="text-align: left">&#160;</td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Sandra Boenisch<sup>(2)</sup></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td><td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">186,883</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">306,700</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7,475</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">501,058</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 20pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Principal Financial Officer
    and</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td><td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">174,900</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">277,603</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">452,503</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 20pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Treasurer</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td><td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">158,300</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">724,314</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">882,614</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif">&#160;</span></td></tr>
  </table>


<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>



<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 1cm; text-indent: -21.8pt"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 1cm; text-indent: -21.8pt"></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0">
<tr style="vertical-align: top">
    <td style="width: 6.6pt">&#160;</td>
    <td style="width: 21.8pt">(1)</td>
    <td>Includes employer matching of defined contribution savings plans.</td></tr>
</table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 1cm; text-indent: -21.8pt">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 1cm; text-indent: -21.8pt"></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 6.6pt"></td><td style="width: 21.8pt">(2)</td><td>Compensation to Ms. Boenisch denominated in Canadian Dollars and has been translated to US dollars at an exchange rate of 0.7416
during the year ended September 30, 2023 (2022: 0.7831; 2021: 0.7915).</td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 1cm; text-indent: -21.8pt">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 1cm; text-indent: -21.8pt"></p>

<!-- Field: Page; Sequence: 98; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->77<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 1cm; text-indent: -21.8pt">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 1cm; text-indent: -21.8pt"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Employment Agreements</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><b>Christopher Missling</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">We and Dr. Missling entered into an
employment agreement dated July 5, 2013, as amended and extended most recently by the third amendment effective April 7, 2022 (the
&#8220;CEO Employment Agreement&#8221;), whereby we currently pay Dr. Missling an annual base salary of $700,000. In addition,
Dr. Missling is eligible to earn an annual cash bonus for each whole or partial calendar year of up to twenty percent of his base
salary, and to participate in our employee benefit plans. We have agreed to indemnify Dr. Missling in connection with his provision
of services to us.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><b>Sandra Boenisch</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><b>&#160;</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">We and Ms. Boenisch entered into an
amended and restated employment agreement dated October 4, 2017, as amended and extended, whereby we currently pay Ms. Boenisch
an annual base salary of $264,000 Canadian dollars. Ms. Boenisch is eligible for discretionary salary increases.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Grants of Plan Based Awards</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The following table sets forth the awards
granted for each named executive officer during the year ended September 30, 2023 under our 2022 Omnibus Incentive Plan:</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
    <td style="font-family: Arial, Helvetica, Sans-Serif; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td><td style="font-family: Arial, Helvetica, Sans-Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td style="font-family: Arial, Helvetica, Sans-Serif; text-align: center; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="11" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>All
    other option awards</b></span></td></tr>
<tr style="vertical-align: bottom">
    <td style="border-bottom: Black 1pt solid; font-weight: bold; text-align: left; padding-top: 0; padding-right: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Name</b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Grant
    Date</b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Number
    of securities underlying options (#)<sup>(1)</sup></b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Exercise
    or base price of option award ($/sh)</b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p><p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p><p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Grant
                                            date fair value of option awards ($) <sup>(2)</sup></b></span></p></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="width: 18%; text-align: left"><p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font: 10pt Times New Roman, Times, Serif">Christopher
Missling, PhD</span></p> <p style="font: 10pt Times New Roman, Times, Serif; margin: 0"></p></td><td style="width: 3%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 18%; text-align: center; padding-left: 2.25pt"><span style="font: 10pt Times New Roman, Times, Serif">March
    31, 2023</span></td><td style="width: 3%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 16%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">500,000</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 3%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td><td style="width: 15%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">8.57</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 3%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td><td style="width: 15%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">3,066,200</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
    <td style="text-align: left"><p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font: 10pt Times New Roman, Times, Serif">Sandra
Boenisch</span></p> <p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font: 10pt Times New Roman, Times, Serif"></span></p></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: center; padding-left: 2.25pt"><span style="font: 10pt Times New Roman, Times, Serif">March 31, 2023</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">50,000</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">8.57</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">306,700</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif">&#160;</span></td></tr>
</table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="letter-spacing: -0.05pt">&#160;</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(1) Represents shares of our common stock underlying options
awarded, each of which vest over time.</p>



<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="letter-spacing: -0.05pt"></span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">(2) <span style="letter-spacing: -0.05pt">Represents</span><span style="letter-spacing: 0.15pt">&#160;</span><span style="letter-spacing: -0.05pt">the</span><span style="letter-spacing: 0.15pt">&#160;</span><span style="letter-spacing: -0.05pt">fair</span><span style="letter-spacing: 0.2pt">&#160;</span><span style="letter-spacing: -0.05pt">value</span><span style="letter-spacing: 0.15pt">&#160;</span><span style="letter-spacing: -0.05pt">of</span><span style="letter-spacing: 0.15pt">&#160;</span><span style="letter-spacing: -0.05pt">each</span><span style="letter-spacing: 0.2pt">&#160;</span><span style="letter-spacing: -0.05pt">equity</span><span style="letter-spacing: 0.15pt">&#160;</span><span style="letter-spacing: -0.05pt">award</span><span style="letter-spacing: 0.2pt">&#160;</span><span style="letter-spacing: -0.05pt">on</span><span style="letter-spacing: 0.15pt">&#160;</span><span style="letter-spacing: -0.05pt">the</span><span style="letter-spacing: 0.15pt">&#160;</span><span style="letter-spacing: -0.05pt">date</span><span style="letter-spacing: 0.2pt">&#160;</span><span style="letter-spacing: -0.05pt">of</span><span style="letter-spacing: 0.15pt">&#160;</span><span style="letter-spacing: -0.05pt">grant,</span><span style="letter-spacing: 0.2pt">&#160;</span><span style="letter-spacing: -0.05pt">as</span><span style="letter-spacing: 0.15pt">&#160;</span><span style="letter-spacing: -0.05pt">computed</span><span style="letter-spacing: 0.15pt">&#160;</span><span style="letter-spacing: -0.05pt">in</span><span style="letter-spacing: 0.2pt">&#160;</span><span style="letter-spacing: -0.05pt">accordance</span><span style="letter-spacing: 0.15pt">&#160;</span><span style="letter-spacing: -0.05pt">with</span><span style="letter-spacing: 0.2pt">&#160;</span><span style="letter-spacing: -0.05pt">FASB</span><span style="letter-spacing: 0.15pt">&#160;</span><span style="letter-spacing: -0.05pt">ASC</span><span style="letter-spacing: 0.15pt">&#160;</span><span style="letter-spacing: -0.05pt">718.</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Outstanding Equity Awards at Fiscal Year-End
</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The following table sets forth for each
named executive officer and director certain information concerning the outstanding equity awards as of September 30, 2023.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 99; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->78<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;<span style="font-family: Times New Roman, Times, Serif"></span></p><table cellpadding="0" cellspacing="0" style="font: 9pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom"><td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="font-size: 10pt; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="3" style="font-size: 10pt; text-align: center; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="font-family: Times New Roman, Times, Serif; font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="7" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Option
    Awards</span></td><td style="font-size: 10pt; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="3" style="font-size: 10pt; text-align: center; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="font-size: 10pt; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font-size: 10pt; text-align: center; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom">
    <td style="border-bottom: Black 1pt solid; padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Name</span></td><td style="font-family: Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; text-align: center"><p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Number
                                            of</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Securities</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Underlying</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Exercisable</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Options</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>(#)</b></span></p></td><td style="font-family: Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; text-align: center"><p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Number
                                            of</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Securities</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Underlying</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Unexercisable</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Options</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>(#)</b></span></p></td><td style="font-family: Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; text-align: center"><p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Equity</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Incentive</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Plan
                                            Awards:</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Number
                                            of</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Securities</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Underlying</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Unexercised</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Unearned</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Options</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>(#)</b></span></p></td><td style="font-family: Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; text-align: center"><p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Option</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Exercise</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Price</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>($)</b></span></p></td><td style="font-family: Times New Roman, Times, Serif; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; text-align: center"><p style="font: 9pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Option</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Expiration</b></span></p> <p style="font: 9pt Times New Roman, Times, Serif; text-align: center; margin-top: 0; margin-bottom: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Date</b></span></p></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; width: 15%; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Christopher</span></td><td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 13%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">73,380</span></td><td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 13%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 13%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 13%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1.32</span></td><td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center; width: 15%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">May 8, 2024</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Missling</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">500,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">0.92</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">April 2, 2025</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">187,500</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.04</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Sept 18, 2025</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">379,625</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.26</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">July 5, 2026</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">861,429</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7.06</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">July 18, 2026</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">500,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.28</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Sept 22, 2026</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">450,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.92</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">May 12, 2027</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">400,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.30</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Dec 13, 2027</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">450,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.30</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">May 15, 2028</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">409,500</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.58</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Oct. 1, 2028</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">750,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.15</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">May 3, 2029</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">550,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.96</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">January 6, 2030</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">550,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.49</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">December 30, 2030</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">500,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">18.11</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">August 2, 2031</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">500,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7.54</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">June 14, 2032</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">500,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">10.09</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">June 27, 2032</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">500,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="font-size: 10pt; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">8.57</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">March 31, 2032</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Sandra Boenisch</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">30,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.30</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Dec 13, 2027</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">30,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.30</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">May 15, 2028</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">27,300</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.58</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Oct. 1, 2028</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">35,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.93</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">June 4, 2029</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">70,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.96</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">January 6, 2030</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">50,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.49</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">December 30, 2030</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">40,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">18.11</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">August 2, 2031</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">40,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">10.09</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">June 27, 2032</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">50,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">8.57</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">March 31, 2032</span></td></tr>
  </table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>
<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Option Exercises and Stock Vested </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The following table sets forth for each
named executive officer awards that were exercised during the year ended September 30, 2023:</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="7" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Option
    Awards</b></span></td></tr>
<tr style="vertical-align: bottom">
    <td style="border-bottom: Black 1pt solid; font-weight: bold; text-align: left; padding-top: 0; padding-right: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Name</b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Number
    of shares acquired on exercise (#)</b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Value
    realized on exercise ($)</b></span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="width: 56%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Christopher
    Missling</span></td><td style="width: 8%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 12%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">500,000</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 8%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 12%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">3,203,340</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Sandra Boenisch</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif">&#160;</span></td></tr>
</table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Nonqualified Defined Contribution and
Other Nonqualified Deferred Compensation Plans</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">There was no nonqualified deferred compensation
for our named executive officers in fiscal 2023.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>CEO Pay Ratio Disclosure</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We are providing the following information
about the relationship of the annual total compensation of our employees and the annual total compensation of our CEO. Based on
the information for fiscal year 2023, we reasonably estimate that the ratio of our CEO&#8217;s annual total compensation to the
annual total compensation of our median employee was 7.7:1. Our pay ratio estimate has been calculated in a manner consistent with
Item 402(u) of Regulation S-K using the data and assumptions summarized below.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 100; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->79<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We identified the median employee by examining
the 2023 annual base salary compensation for all&#160;individuals,&#160;excluding&#160;our&#160;CEO.&#160;We excluded independent
contractors retained on an as needed basis, whose compensation is determined by an unaffiliated third party, and who are therefore
are not considered our employees for purposes of the pay ratio calculation.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We&#160;included&#160;all employees who were
employed by us as of September 30, 2023.&#160;We selected the determination date and measurement period because they are recent
periods for which employee census and compensation information are readily available. Salaries and wages were annualized for those
employees who were not employed for the full year of fiscal 2023. We selected annual base salary as our compensation measure because
it is readily available in our existing payroll systems, it is consistently calculated for each employee, and because it is a reasonable
proxy for total compensation for purposes of determining the median employee. We did not apply any cost-of-living adjustments to
the compensation of employees in jurisdictions other than the jurisdiction in which the CEO resides.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Once we identified our median employee, we
calculated such employee&#8217;s annual total compensation for 2023 in accordance with the requirements of Item 402(c)(2)(x) of
Regulation S-K, resulting in that employee&#8217;s annual total compensation of $512,245. The median employee&#8217;s annual total
compensation includes annualized base salary, annualized bonus, annualized 401(k) matching contributions, and the fair value of
awards granted during the fiscal year ended September 30, 2023 under our 2022 Omnibus Incentive Plan.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">With respect to the CEO, we used the amount
reported as total compensation in the Summary Compensation Table included in this annual report on Form 10-K. Any estimates and
assumptions used to calculate total annual compensation are described in footnotes to the Summary Compensation Table.</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Compensation of Directors </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The table below shows the compensation
of our directors who were not our named executive officers for the fiscal year ended September 30, 2023:</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
    <td style="border-bottom: Black 1pt solid; font-weight: bold; text-align: left; padding-top: 0; padding-right: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Name</b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Fees
    Earned or Paid in Cash<br /> ($)</b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Stock&#160;<br />
    Awards&#160;<br /> ($)</b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p><p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p><p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Option&#160;<br />
                                            Awards&#160;<br />
                                            ($) <sup>(1)</sup></b></span></p></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Non-Equity
    Incentive Plan Compensation ($)</b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Nonqualified
    Deferred Compensation Earnings ($)</b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>All
    Other Compensation&#160;($)</b></span></td><td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Total&#160;<br />
    ($)</b></span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="width: 37%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Jiong
    Ma</span></td><td style="width: 2%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 5%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">33,000</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 2%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 5%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 2%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 5%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">316,540</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 2%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 5%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 2%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 5%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 2%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 5%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 2%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="width: 5%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">349,540</span></td><td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Claus van der Velden</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">41,000</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">316,540</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">357,540</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Athanasios Skarpelos</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">25,000</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">316,540</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">341,540</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Steffen Thomas</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">25,000</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">316,540</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">341,540</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Peter Donhauser</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">25,000</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">316,540</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td><td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td><td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">341,540</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif">&#160;</span></td></tr>
</table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">(1) Includes stock option awards valued
based on the aggregate grant date fair value of the award computed in accordance with FASB ASC Topic 718. The amounts shown in
the table above do not necessarily reflect the actual value that may be realized by the&#160;non-employee&#160;director upon vesting.
On September 30, 2023, the aggregate number of outstanding vested and unvested stock option awards held by each director was as
follows: Dr. Ma possessed options to purchase 160,000 shares, Dr. van der Velden possessed options to purchase 305,500 shares,
Mr. Skarpelos possessed options to purchase 355,500 shares, Dr. Thomas possessed options to purchase 405,500 shares and Dr. Donhauser
possessed options to purchase 305,500 shares.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">We currently compensate non-employee
directors $25,000 per year, paid quarterly. We compensate Dr. Ma an additional $4,000 per quarter for acting as Chair. We compensate
Claus van der Velden an additional $4,000 per quarter for performing the functions of Chairman of the Audit Committee, Compensation
Committee and Nominating and Corporate Governance Committee.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 101; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->80<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">We regularly grant members of the Board
of Directors awards of options. Each board member is granted options initially when they join the Board of Directors, which typically
vest over a three-year period. Additionally, we grant awards on an annual basis. Annual awards of options typically vest in full
on the first anniversary of grant date. In 2023, the annual grant was 50,000 options to each director.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">In addition, directors are entitled
to reimbursement for reasonable travel and other out-of-pocket expenses incurred in connection with attendance at meetings of our
Board of Directors. Our Board of Directors may award further special remuneration to any director undertaking any special services
on our behalf other than services ordinarily required of a director.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Retirement or Similar Benefit Plans</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">There are no arrangements or plans in
which we provide retirement or similar benefits for our directors or executive officers.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Resignation, Retirement, Other Termination,
or Change in Control Arrangements</i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>Potential Payments Upon Termination</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Company is a party to employment
contracts with our Chief Executive Officer and Principal Financial Officer that contain provisions for payment of severance upon
termination by either the Company without cause or by the employee for good reason. General terms of these arrangements are described
below.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Our CEO Employment Agreement with Dr.
Missling contains provisions regarding our obligations upon his termination and upon a Change in Control. Any capitalized term
not defined herein is used as defined in the CEO Employment Agreement. If Dr. Missling&#8217;s employment is terminated by us without
Cause, he is entitled to receive payments by us consisting of (i) reimbursement of any unpaid business expenses to which he is
entitled to reimbursement that were incurred prior to the effective date of his termination, (ii) all vested compensation and benefits
to which he is entitled as of the Termination Date, (iii) a severance payment consisting of the three times the sum of (a) his
annual salary in effect at the time of termination and (b) the average of the annual Bonuses payable to him for the last three
completed calendar years prior to the Termination Date, (iv) all outstanding and unvested stock options and all options previously
vested will become and remain exercisable for no less than three years from the Termination Date; (v) all of his unvested and outstanding
restricted stock, restricted stock units or other equity awards that are unvested and outstanding as of the Termination Date shall
vest and be settled within ten business days after the Termination Date, (vi) life insurance coverage until the end of the term
of the CEO Employment Agreement; and (vii) continued participation in all medical, dental and hospitalization benefits plans or
programs for Dr. Missling and his eligible dependents for 36 months or until he receives similar benefits at a new employer, at
his sole cost. If Dr. Missling&#8217;s employment is terminated by him for Good Reason, he is entitled to receive the same as the
above, however the severance payment will consist of three times his annual salary in effect at the time of termination and two
times the average annual Bonuses payable to him for the last three completed calendar years prior to the Termination Date.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">If Dr. Missling was terminated by the
Company without cause on September 30, 2023, he would have been entitled to a severance payment of $2,444,750. If Dr. Missling
terminated his employment for Good Reason on September 30, 2023, he would have been entitled to a severance payment of $2,329,800.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Our CFO Employment Agreement with Ms.
Boenisch contains provisions regarding our obligations upon her termination. Any capitalized term not defined herein is used as
defined in the CFO Employment Agreement. Under the CFO Employment Agreement, if Ms. Boenisch is terminated without Cause, the Company
shall pay Ms. Boenisch severance compensation equal to six months base salary payable by the Company for the six-month period following
the Termination. In addition, the Company must provide Ms. Boenisch thirty (30) day notice of her Termination. If the Company opts
to have Ms. Boenisch cease providing services to the Company prior to the expiration of the thirty (30) day notice-period (the
&#8220;Notice Period&#8221;), Ms. Boenisch shall receive the Compensation and Benefits for the full length of the Notice Period
as if such period was not waived. In addition, any unvested stock options or stock awards vesting in the contract year of Termination
held by Ms. Boenisch as of the Date of Termination shall immediately vest.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 102; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->81<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">If Ms. Boenisch was terminated by the
Company without cause on September 30, 2023, she would have been entitled to continued salary payments equal to $97,890 in total.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The following table presents accelerated
vesting for certain equity awards outstanding at the time of the executive&#8217;s termination for each Named Executive Officer,
if employment were terminated by either the Company without cause or by Dr. Missling for good reason on September 30, 2023:</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
<td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
<td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
<td colspan="7" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Vesting
Upon Termination</b></span></td></tr>
<tr style="vertical-align: bottom">
<td style="border-bottom: Black 1pt solid; font-weight: bold; text-align: left; padding-top: 0; padding-right: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Named
Executive Officer</b></span></td>
<td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Unvested
Stock Options (#)</b></span></td>
<td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Stock
Option Awards &#160; Estimated Benefit ($)<sup>(1)</sup></b></span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="width: 56%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Dr. Christopher Missling</span></td>
<td style="width: 8%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 12%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">2,550,000</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 8%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 12%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">583,000</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Sandra Boenisch</span></td>
<td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">(2)</span></td>
<td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif">&#160;</span></td></tr>
</table>


<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">(1) Estimated benefit based on the closing
stock price of $6.55 at September 30, 2023.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">(2) Ms. Boenisch&#8217;s unvested stock
options at September 30, 2023 all contained performance based vesting conditions, therefore such options would not automatically
vest upon Termination.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>Potential Payments Upon Change in
Control</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">If the Company is subject to a Change
in Control, then the CEO Employment Agreement and the CFO Employment Agreement provide that all previously granted but unvested
stock options held by Dr. Missling and Ms. Boenisch shall vest.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The following table presents accelerated
vesting for certain equity awards outstanding to the Named Executive Officer, if a change in control had occurred at September
30, 2023:</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
<td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
<td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
<td colspan="7" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Vesting
Due to Change in Control</b></span></td></tr>
<tr style="vertical-align: bottom">
<td style="border-bottom: Black 1pt solid; font-weight: bold; text-align: left; padding-top: 0; padding-right: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Named
Executive Officer</b></span></td>
<td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Unvested
Stock Options (#)</b></span></td>
<td style="font-weight: bold; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Stock
Option Awards &#160; Estimated Benefit ($)<sup>(1)</sup></b></span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="width: 56%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Dr. Christopher Missling</span></td>
<td style="width: 8%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 12%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">2,550,000</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 8%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 12%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">583,000</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Sandra Boenisch</span></td>
<td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">180,000</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">53,000</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif">&#160;</span></td></tr>
</table>


<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">(1) Estimated benefit based on the closing
stock price of $6.55 at September 30, 2023.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">For a complete description of these
terms and conditions please refer to the CEO Employment Agreement and CFO Employment Agreement (and their amendments) filed as
exhibits to this Annual Report on Form 10-K.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-style: normal"><span id="a_020"></span>ITEM 12. SECURITY
OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS.</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The following table sets forth, as of
November 24, 2023, certain information with respect to the beneficial ownership of our common stock by each stockholder known by
us to be the beneficial owner of more than 5% of our common stock and by each of our current directors and our named executive
officers and by our current directors and executive officers as a group. We have determined the number and percentage of shares
beneficially owned by such person in accordance with Rule 13d-3 under the Securities Exchange Act of 1934. This information does
not necessarily indicate beneficial ownership for any other purpose.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 103; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->82<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%">
  <tr style="vertical-align: bottom">
    <td style="padding: 0pt 0pt 0pt 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Name and address of</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Amount and nature
    of</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Percent of</span></td></tr>
  <tr style="vertical-align: bottom">
    <td style="border-bottom: Black 1pt solid; padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Title of class</span></td><td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">beneficial owner</span></td><td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">beneficial ownership</span></td><td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">class <sup>(1)</sup></span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td colspan="3" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Directors and Named Executive Officers</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; width: 22%; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common</span></td><td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 21%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Christopher Missling</span></td><td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 19%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7,311,644</span></td><td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i><sup>(2)</sup></i></span></td><td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="width: 19%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">8.3</span></td><td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Stock</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(CEO/Director)</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Jiong Ma (Director,</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">65,000</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i><sup>(3)</sup></i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">*</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Stock</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chair)</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Claus van der Velden</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">222,167</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i><sup>(4)</sup></i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">*</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Stock</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Director)</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Athanasios Skarpelos</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,578,625</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i><sup>(5)</sup></i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1.9</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Stock</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Director)</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Steffen Thomas</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">322,167</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i><sup>(6)</sup></i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">*</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Stock</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Director)</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Peter Donhauser</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">224,332</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i><sup>(7)</sup></i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">*</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Stock</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Director)</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Sandra Boenisch</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">265,263</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i><sup>(8)</sup></i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">*</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Stock</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Principal Financial</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Officer)</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common</span></td><td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Directors
    &amp; Executive</span></td><td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,989,198</span></td><td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">11.2</span></td><td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Stock</span></td><td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Officers
    as a group (7</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">persons)</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5%
    Holders</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The Vanguard Group</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">4,144,500</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i><sup>(9)</sup></i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.0</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Stock</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">100 Vanguard Blvd</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Malvern, PA 19355</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">State Street Corporation</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5,812,605</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i><sup>(9)</sup></i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7.1</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Stock</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1 Lincoln Street</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Boston, MA 02111</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">BlackRock, Inc.</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5,578,159</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i><sup>(10)</sup></i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.8</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td></tr>
  <tr style="vertical-align: bottom; background-color: White">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Stock</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">55 East 52<sup>nd</sup> Street</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
    <td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">New York, NY 10055</span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>&#160;</i></span></td><td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td><td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif">&#160;</span></td></tr>
  </table>


<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;<span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>


<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 18pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">(1)</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Percentage
                                                                                                                             of
                                                                                                                             ownership
                                                                                                                             is
                                                                                                                             based
                                                                                                                             on
                                                                                                                             82,086,511
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             issued
                                                                                                                             and
                                                                                                                             outstanding
                                                                                                                             as
                                                                                                                             of
                                                                                                                             November
                                                                                                                             24,
                                                                                                                             2023.
                                                                                                                             Except
                                                                                                                             as
                                                                                                                             otherwise
                                                                                                                             indicated,
                                                                                                                             we
                                                                                                                             believe
                                                                                                                             that
                                                                                                                             the
                                                                                                                             beneficial
                                                                                                                             owners
                                                                                                                             of
                                                                                                                             the
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             listed
                                                                                                                             above,
                                                                                                                             based
                                                                                                                             on
                                                                                                                             information
                                                                                                                             furnished
                                                                                                                             by
                                                                                                                             such
                                                                                                                             owners,
                                                                                                                             have
                                                                                                                             sole
                                                                                                                             investment
                                                                                                                             and
                                                                                                                             voting
                                                                                                                             power
                                                                                                                             with
                                                                                                                             respect
                                                                                                                             to
                                                                                                                             such
                                                                                                                             shares,
                                                                                                                             subject
                                                                                                                             to
                                                                                                                             community
                                                                                                                             property
                                                                                                                             laws
                                                                                                                             where
                                                                                                                             applicable.
                                                                                                                             Beneficial
                                                                                                                             ownership
                                                                                                                             is
                                                                                                                             determined
                                                                                                                             in
                                                                                                                             accordance
                                                                                                                             with
                                                                                                                             the
                                                                                                                             rules
                                                                                                                             of
                                                                                                                             the
                                                                                                                             Commission
                                                                                                                             and
                                                                                                                             generally
                                                                                                                             includes
                                                                                                                             voting
                                                                                                                             or
                                                                                                                             investment
                                                                                                                             power
                                                                                                                             with
                                                                                                                             respect
                                                                                                                             to
                                                                                                                             securities.
                                                                                                                             Shares
                                                                                                                             of
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             subject
                                                                                                                             to
                                                                                                                             options
                                                                                                                             or
                                                                                                                             warrants
                                                                                                                             currently
                                                                                                                             exercisable
                                                                                                                             or
                                                                                                                             exercisable
                                                                                                                             within
                                                                                                                             60
                                                                                                                             days,
                                                                                                                             are
                                                                                                                             deemed
                                                                                                                             outstanding
                                                                                                                             for
                                                                                                                             purposes
                                                                                                                             of
                                                                                                                             computing
                                                                                                                             the
                                                                                                                             percentage
                                                                                                                             ownership
                                                                                                                             of
                                                                                                                             the
                                                                                                                             person
                                                                                                                             holding
                                                                                                                             such
                                                                                                                             option
                                                                                                                             or
                                                                                                                             warrants
                                                                                                                             but
                                                                                                                             are
                                                                                                                             not
                                                                                                                             deemed
                                                                                                                             outstanding
                                                                                                                             for
                                                                                                                             purposes
                                                                                                                             of
                                                                                                                             computing
                                                                                                                             the
                                                                                                                             percentage
                                                                                                                             ownership
                                                                                                                             of
                                                                                                                             any
                                                                                                                             other
                                                                                                                             person.</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif"></span></p>

<!-- Field: Page; Sequence: 104; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->83<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 18pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">(2)</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Includes
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             73,380
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $1.32
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             500,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $0.92
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             187,500
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $5.04
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             379,625
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $6.26
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             861,429
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $7.06
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             500,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $3.28
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             450,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $5.92
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             400,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $3.30
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             450,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.30
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             409,500
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.58
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             750,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $3.15
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             550,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.96
                                                                                                                             per
                                                                                                                             share
                                                                                                                             and
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             550,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $5.49
                                                                                                                             per
                                                                                                                             share
                                                                                                                             that
                                                                                                                             are
                                                                                                                             vested
                                                                                                                             or
                                                                                                                             are
                                                                                                                             vesting
                                                                                                                             within
                                                                                                                             60
                                                                                                                             days.
                                                                                                                             Excludes
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             500,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $18.11
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             500,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $7.54
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             500,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $10.09
                                                                                                                             per
                                                                                                                             share
                                                                                                                             and
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             500,000
                                                                                                                             shares
                                                                                                                             at
                                                                                                                             $8.57
                                                                                                                             per
                                                                                                                             share
                                                                                                                             that
                                                                                                                             do
                                                                                                                             not
                                                                                                                             vest
                                                                                                                             within
                                                                                                                             60
                                                                                                                             days.</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 18pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">(3)</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Includes
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             23,333
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $13.01
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             25,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $18.11
                                                                                                                             per
                                                                                                                             share
                                                                                                                             and
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             16,667
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $10.09
                                                                                                                             per
                                                                                                                             share
                                                                                                                             that
                                                                                                                             have
                                                                                                                             vested
                                                                                                                             or
                                                                                                                             are
                                                                                                                             vesting
                                                                                                                             within
                                                                                                                             60
                                                                                                                             days.
                                                                                                                             Excludes
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             11,667
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $13.01
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             33,333
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $10.09
                                                                                                                             per
                                                                                                                             share
                                                                                                                             and
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             50,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $8.57
                                                                                                                             per
                                                                                                                             share
                                                                                                                             that
                                                                                                                             do
                                                                                                                             not
                                                                                                                             vest
                                                                                                                             within
                                                                                                                             60
                                                                                                                             days.</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 18pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">(4)</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Includes
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             50,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.60
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             45,500
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.58
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             50,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.96
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             35,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $5.49
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             25,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $18.11
                                                                                                                             per
                                                                                                                             share
                                                                                                                             and
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             16,667
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $10.09
                                                                                                                             per
                                                                                                                             share
                                                                                                                             that
                                                                                                                             have
                                                                                                                             vested
                                                                                                                             or
                                                                                                                             are
                                                                                                                             vesting
                                                                                                                             within
                                                                                                                             60
                                                                                                                             days.
                                                                                                                             Excludes&#160;options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             33,333
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $10.09
                                                                                                                             per
                                                                                                                             share
                                                                                                                             and
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             50,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $8.57
                                                                                                                             per
                                                                                                                             share
                                                                                                                             that
                                                                                                                             are
                                                                                                                             not
                                                                                                                             vesting
                                                                                                                             within
                                                                                                                             60
                                                                                                                             days.</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 18pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">(5)</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Includes
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             100,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $3.28
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             45,500
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.58
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             50,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.96
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             35,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $5.49
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             25,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $18.11
                                                                                                                             per
                                                                                                                             share
                                                                                                                             and
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             16,667
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $10.09
                                                                                                                             per
                                                                                                                             share
                                                                                                                             that
                                                                                                                             have
                                                                                                                             vested
                                                                                                                             or
                                                                                                                             are
                                                                                                                             vesting
                                                                                                                             within
                                                                                                                             60
                                                                                                                             days.
                                                                                                                             Excludes
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             33,333
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $10.09
                                                                                                                             per
                                                                                                                             share
                                                                                                                             and
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             50,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $8.57
                                                                                                                             per
                                                                                                                             share
                                                                                                                             that
                                                                                                                             do
                                                                                                                             not
                                                                                                                             vest
                                                                                                                             within
                                                                                                                             60
                                                                                                                             days.</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 18pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">(6)</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Includes
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             50,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $1.76
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             100,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $3.28
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             45,500
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.58
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             50,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.96
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             35,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $5.49
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             25,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $18.11
                                                                                                                             per
                                                                                                                             share
                                                                                                                             and
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             16,667
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $10.09
                                                                                                                             per
                                                                                                                             share
                                                                                                                             that
                                                                                                                             have
                                                                                                                             vested
                                                                                                                             or
                                                                                                                             are
                                                                                                                             vesting
                                                                                                                             within
                                                                                                                             60
                                                                                                                             days.
                                                                                                                             Excludes
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             33,333
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $10.09
                                                                                                                             per
                                                                                                                             share
                                                                                                                             and
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             50,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $8.57
                                                                                                                             per
                                                                                                                             share
                                                                                                                             that
                                                                                                                             are
                                                                                                                             not
                                                                                                                             vesting
                                                                                                                             within
                                                                                                                             60
                                                                                                                             days.</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 18pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">(7)</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Includes
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             50,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $5.39
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             45,500
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.58
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             50,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.96
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             35,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $5.49
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             25,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $18.11
                                                                                                                             per
                                                                                                                             share
                                                                                                                             and
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             16,667
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $10.09
                                                                                                                             per
                                                                                                                             share
                                                                                                                             that
                                                                                                                             have
                                                                                                                             vested
                                                                                                                             or
                                                                                                                             are
                                                                                                                             vesting
                                                                                                                             within
                                                                                                                             60
                                                                                                                             days.
                                                                                                                             Excludes
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             33,333
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $10.09
                                                                                                                             per
                                                                                                                             share
                                                                                                                             and
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             50,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $8.57
                                                                                                                             per
                                                                                                                             share
                                                                                                                             that
                                                                                                                             are
                                                                                                                             not
                                                                                                                             vesting
                                                                                                                             within
                                                                                                                             60
                                                                                                                             days.</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 18pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">(8)</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">Includes
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             30,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $3.30
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             30,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.30
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             27,300
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.58
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             35,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.93
                                                                                                                             per
                                                                                                                             share,
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             70,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $2.96
                                                                                                                             per
                                                                                                                             share
                                                                                                                             and
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             50,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $5.49
                                                                                                                             per
                                                                                                                             share
                                                                                                                             that
                                                                                                                             have
                                                                                                                             vested
                                                                                                                             or
                                                                                                                             are
                                                                                                                             vesting
                                                                                                                             within
                                                                                                                             60
                                                                                                                             days.
                                                                                                                             Excludes
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             40,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $18.11
                                                                                                                             per
                                                                                                                             share
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             40,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $10.09
                                                                                                                             per
                                                                                                                             share
                                                                                                                             and
                                                                                                                             options
                                                                                                                             to
                                                                                                                             purchase
                                                                                                                             50,000
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             our
                                                                                                                             common
                                                                                                                             stock
                                                                                                                             at
                                                                                                                             $8.57
                                                                                                                             per
                                                                                                                             share
                                                                                                                             that
                                                                                                                             do
                                                                                                                             not
                                                                                                                             vest
                                                                                                                             within
                                                                                                                             60
                                                                                                                             days.</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 18pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">(9)</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">Based
                                                                                                                             on
                                                                                                                             Schedule
                                                                                                                             13G
                                                                                                                             as
                                                                                                                             filed
                                                                                                                             with
                                                                                                                             the
                                                                                                                             SEC
                                                                                                                             and
                                                                                                                             dated
                                                                                                                             on
                                                                                                                             February
                                                                                                                             9,
                                                                                                                             2023</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 18pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">(10)</span></td><td><span style="font: 10pt Times New Roman, Times, Serif">Based
                                                                                                                              on
                                                                                                                              Schedule
                                                                                                                              13G
                                                                                                                              as
                                                                                                                              filed
                                                                                                                              with
                                                                                                                              the
                                                                                                                              SEC
                                                                                                                              and
                                                                                                                              dated
                                                                                                                              on
                                                                                                                              January
                                                                                                                              31,
                                                                                                                              2023</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-indent: -18pt">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-indent: -18pt"></p>

<!-- Field: Page; Sequence: 105; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->84<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-indent: -18pt">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-indent: -18pt"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><b><i>Change in Control</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">We are unaware of any contract or other arrangement, the
operation of which may at a subsequent date result in a change of control of our Company.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><b><i>Securities Authorized for Issuance under Equity Compensation
Plans or Individual Compensation Arrangements </i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The following table summarizes certain information regarding
our equity compensation plan or individual compensation arrangements at September 30, 2023:</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
<td colspan="13" style="font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Equity
Compensation Plan Information</b></span></td></tr>
<tr style="vertical-align: bottom">
<td style="font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Plan
Category</b></span></td>
<td style="font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
<td colspan="3" style="font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Number
of securities to be issued upon exercise of outstanding options, warrants and rights<br /> (a)</b></span></td>
<td style="font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
<td colspan="3" style="font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Weighted-average
exercise price of outstanding options, warrants and rights<br /> (b)</b></span></td>
<td style="font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
<td colspan="3" style="font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Number
of securities remaining available for future issuances under equity compensation plans (excluding securities reflected in column (a))<br />
(c)</b></span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="width: 46%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Equity compensation plans approved by security holders</span></td>
<td style="width: 5%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 11%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">22,050,553</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 5%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 11%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">7.40</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 5%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 11%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">6,661,535</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Equity compensation plans not approved by security holders</span></td>
<td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="font-weight: bold"><span style="font: 10pt Times New Roman, Times, Serif"><b>Total</b></span></td>
<td style="font-weight: bold"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-weight: bold; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-weight: bold; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">22,050,553</span></td>
<td style="font-weight: bold; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-weight: bold"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-weight: bold; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-weight: bold; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">7.40</span></td>
<td style="font-weight: bold; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-weight: bold"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-weight: bold; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="font-weight: bold; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">6,66</span><span style="font-family: Times New Roman, Times, Serif">1,535</span></td>
<td style="font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif">&#160;</span></td></tr>
</table>


<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>2022 Stock Option Plan</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">On March 25, 2022, the Board approved
the 2022 Omnibus Incentive Plan (the &#8220;2022 Plan&#8221;). The 2022 Plan was approved by stockholders on May 24, 2022. Under
the terms of the 2022 Plan, 10,000,000 shares of Common Stock were made available for issuance under the 2022 Plan, in addition
to the shares available under the 2019 Omnibus Incentive Plan (the &#8220;2019 Plan&#8221;) and the 2015 Omnibus Incentive Plan
(the &#8220;2015 Plan&#8221;). Any awards outstanding under a previous stock option plan will remain subject to and be paid under
such plan, and any shares subject to outstanding awards under a previous plan that subsequently cease to be subject to such awards
(other than by reason of settlement of the awards in shares) will automatically become available for issuance under the 2022 Plan.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The 2022 Plan provides that it may be
administered by the Board, or the Board may delegate such responsibility to a committee. The exercise price will be determined
by the Board at the time of grant shall be at least equal to the fair market value on such date. If the grantee is a 10% stockholder
on the grant date, then the exercise price shall not be less than 110% of fair market value of the Company&#8217;s shares of common
stock on the grant date. Stock options may be granted under the 2022 Plan for an exercise period of up to ten years from the date
of grant of the option or such lesser periods as may be determined by the Board, subject to earlier termination in accordance with
the terms of the 2022 Plan.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The purpose of the 2022 Plan is to retain
the services of valued key employees and consultants of our Company and such other persons, and to encourage such persons to acquire
a greater proprietary interest in our Company, thereby strengthening their incentive to achieve the objectives of the shareholders
of our Company. The purpose is also to serve as an aid and inducement in the hiring of new employees and to provide an equity incentive
to consultants.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 106; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->85<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_021"></span>ITEM 13. CERTAIN
RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR INDEPENDENCE </span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Transactions with related persons</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">There have been no transactions, since
October 1, 2022, or currently proposed transactions, in which we were or are to be a participant and the amount involved exceeds
the lesser of $120,000 or one percent of the average of the smaller reporting company&#8217;s total assets at year end for the
last two completed fiscal years, and in which any of the following persons had or will have a direct or indirect material interest.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 18pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">i.</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">any
                                                                                                                            director
                                                                                                                            or
                                                                                                                            executive
                                                                                                                            officer
                                                                                                                            of
                                                                                                                            our
                                                                                                                            Company;</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 18pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">ii.</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">any
                                                                                                                             beneficial
                                                                                                                             owner
                                                                                                                             of
                                                                                                                             shares
                                                                                                                             carrying
                                                                                                                             more
                                                                                                                             than
                                                                                                                             5%
                                                                                                                             of
                                                                                                                             the
                                                                                                                             voting
                                                                                                                             rights
                                                                                                                             attached
                                                                                                                             to
                                                                                                                             our
                                                                                                                             outstanding
                                                                                                                             shares
                                                                                                                             of
                                                                                                                             common
                                                                                                                             stock;
                                                                                                                             and</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></p>

<table cellpadding="0" cellspacing="0" style="font: 10pt/normal Times New Roman, Times, Serif; width: 100%; margin-top: 0; margin-bottom: 0"><tr style="vertical-align: top">
<td style="width: 18pt"></td><td style="width: 18pt"><span style="font: 10pt Times New Roman, Times, Serif">iii.</span></td><td style="text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif">any
                                                                                                                              member
                                                                                                                              of
                                                                                                                              the
                                                                                                                              immediate
                                                                                                                              family
                                                                                                                              (including
                                                                                                                              spouse,
                                                                                                                              parents,
                                                                                                                              children,
                                                                                                                              siblings
                                                                                                                              and
                                                                                                                              in-laws)
                                                                                                                              of
                                                                                                                              any
                                                                                                                              of
                                                                                                                              the
                                                                                                                              foregoing
                                                                                                                              persons.</span></td></tr></table>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -18pt">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Compensation of Named Executive
Officers and Directors</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">For information regarding compensation
of named executive officers and directors, please see &#8220;Item 11. Executive Compensation.&#8221;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Director Independence</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Under the NASDAQ Stock Market Rules,
the Board has a responsibility to make an affirmative determination that those members of its Board that serve as independent directors
do not have any relationships with the Company and its businesses that would impair their independence. The Board has determined
that that Christopher Missling, PhD is not independent, as that term is defined by NASDAQ 5605(a)(2), because Mr. Missling serves
as our President, Chief Executive Officer, and Secretary.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The Board has determined that that Claus
van der Velden, Athanasios Skarpelos, Steffen Thomas, Peter Donhauser and Jiong Ma are independent, as that term is defined by
NASDAQ 5605(a)(2) and the applicable rules of the Commission.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Board Meetings</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">During fiscal 2023, each member of the
Board of Directors attended at least 75% of the aggregate of all meetings of the Board of Directors and all meetings of committees
of the Board of Directors on which such director served that were held during the period in which such director served.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_022"></span>ITEM 14. PRINCIPAL
ACCOUNTING FEES AND SERVICES </span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Fees Paid to Our Independent Registered
Public Accounting Firm </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">The following table sets forth the aggregate
fees billed or expected to be billed to our Company for professional services rendered by our independent registered public accounting
firm, Grant Thornton, LLP for the fiscal years ended September 30, 2023 and 2022:</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 100%">
<tr style="vertical-align: bottom">
<td style="font-family: Arial, Helvetica, Sans-Serif; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">2023</span></td>
<td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font: 10pt Times New Roman, Times, Serif">2022</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="width: 56%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Audit Fees</span></td>
<td style="width: 8%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td>
<td style="width: 12%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">444,098</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 8%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td>
<td style="width: 12%; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">398,900</span></td>
<td style="width: 1%; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Audit Related Fees</span></td>
<td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Tax Fees</span></td>
<td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">All Other Fees</span></td>
<td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">&#8212;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">Total Fees</span></td>
<td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td>
<td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">444,098</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
<td style="text-align: left"><span style="font: 10pt Times New Roman, Times, Serif">$</span></td>
<td style="text-align: right"><span style="font: 10pt Times New Roman, Times, Serif">398,900</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif">&#160;</span></td></tr>
</table>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 107; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->86<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Audit Fees.</i></b> Consist of
fees billed for professional services rendered for the audits of our financial statements, reviews of our interim financial statements
included in quarterly reports, services performed in connection with regular filings with the Commission for the fiscal years ended
September 30, 2023 and 2022 in connection with statutory and regulatory filings or engagements.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>Policy on Pre-Approval by Audit Committee
of Services Performed by Independent Registered Public Accounting Firm </i></b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><b><i>&#160;</i></b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Our Audit Committee pre-approves all
services provided by our independent registered public accounting firm. All of the above services and fees were reviewed and approved
by our Audit Committee.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><b>&#160;</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">Our Audit Committee has considered the
nature and amount of fees billed or expected to be billed by Grant Thornton LLP and believes that the provision of services for
activities unrelated to the audit was compatible with maintaining Grant Thornton LLP&#8217;s independence.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<!-- Field: Page; Sequence: 108; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->87<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span id="a_023"></span>PART IV</p>

<p style="font: bold 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_024"></span>ITEM 15. EXHIBITS,
FINANCIAL STATEMENT SCHEDULES</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="text-transform: uppercase"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="text-transform: uppercase"><b></b></span></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <tr style="vertical-align: top">
    <td style="padding: 0pt; width: 10%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Exhibit</b></span></td>
    <td style="padding: 0pt; width: 90%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  <tr style="vertical-align: top">
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Number</b></span></td>
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Description</b></span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>(3)</b></span></td>
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Articles of Incorporation and Bylaws</b></span></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.1</span></td>
    <td style="padding: 0pt; text-align: justify; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000161577419007324/s118023_ex3-1.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Articles of Incorporation, as amended (incorporated by reference to our Annual Report on Form 10-K for the year ended September 30, 2021 filed on November 24, 2021)</span></a></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.3</span></td>
    <td style="padding: 0pt; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000108503707002199/exhibit3_1.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Bylaws (incorporated by reference to our Current Report on Form 8-K filed on September 28, 2007)</span></a></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>(4)</b></span></td>
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Instruments Defining the Rights of Security Holders</b></span></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.1</span></td>
    <td style="padding: 0pt; text-align: justify; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000173112222002062/e4251_ex4-1.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Description of Registrant&#8217;s Securities (incorporated by reference to our Annual Report on Form 10-K filed on November 28, 2022)</span></a></td></tr>
  <tr style="vertical-align: top; background-color: White">
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.2</span></td>
    <td style="padding: 0pt; text-align: justify; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000173112223000152/e4385_ex4-1.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Registration Rights Agreement, dated February 3, 2023, by and between the Company and Lincoln Park Capital Fund, LLC (incorporated by reference to our Quarterly Report on Form 10-Q filed on February 7, 2023)</span></a></td></tr>
  <tr style="vertical-align: top; background-color: rgb(204,238,255)">
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>(10)</b></span></td>
    <td style="padding: 0pt; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Material Contracts</b></span></td></tr>

<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">10.1&#94;</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000161577415003756/s102397_ex10-91.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">2015 Omnibus Incentive Plan (incorporated by reference to our Annual Report on Form 10-K filed on December 29, 2015)</span></a></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">10.2&#94;</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000161577419002242/s115994_def14a.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">2019 Omnibus Incentive Plan (incorporated by reference to our Proxy Statement, dated February 11, 2019, as filed on February 11, 2019)</span></a></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">10.3&#94;</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000173112222001056/e3822_ex5-1.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">2022 Omnibus Incentive Plan (incorporated by reference to our Registration Statement on Form S-8, as filed on June 10, 2022)</span></a></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">10.4&#94;</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000106299314004769/exhibit31-1.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Employment Agreement, dated as of July 5, 2013, by and between the Company and Christopher Missling, PhD (incorporated by reference to our Quarterly Report on Form 10-Q filed on August 13, 2014)</span></a></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">10.5&#94;</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000161577416006259/s103666_ex10-1.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">First Amendment to Employment Agreement, dated as of July 5, 2016, by and between the Company and Christopher Missling, PhD (incorporated by reference to our Current Report on Form 8-K filed on July 7, 2016)</span></a></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">10.6&#94;</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000161577416006410/s103735_ex10-1.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Amended and Restated First Amendment to Employment Agreement, dated as of July 18, 2016, by and between the Company and Christopher Missling, PhD (incorporated by reference to our Current Report on Form 8-K filed on July 22, 2016)</span></a></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">10.7&#94;</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000161577419007324/s118023_ex10-1.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Second Amendment to Employment Agreement, dated as of May 3, 2019 by and between the Company and Christopher Missling, PhD (incorporated by reference to our Quarterly Report on Form 10-Q filed on May 9, 2019) </span></a></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">10.8&#94;</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000173112222000700/e3692_ex10-1.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Third Amendment to Employment Agreement, dated April 7, 2022 by and between the Company and Christopher Missling, PhD (incorporated by reference to our Current Report on Form 8-K filed on April 8, 2022)</span></a></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">10.9&#94;</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000161577417007272/s108360_ex10-7.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Amended and Restated Employment Agreement by and between the Company and with Sandra Boenisch (incorporated by reference to our Annual Report on Form 10-K filed on December 11, 2017)</span></a></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">10.10&#94;</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000173112220000103/e1699_10-1.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Amendment No. 1 to Amended and Restated Employment Agreement between the Company and Sandra Boenisch, dated February 4, 2020 (incorporated by reference to our Quarterly Report on Form 10-Q filed on February 6, 2020)</span></a></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">10.11&#94;</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000173112220000103/e1699_10-1.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Amendment No. 2 to Amended and Restated Employment Agreement between the Company and Sandra Boenisch, dated February 28, 2022 (incorporated by reference to our Current Report on Form 8-K filed on March 4, 2022)</span></a></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">10.12</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000173112220000432/e1889_ex1-1.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Amended and Restated Sales Agreement, dated May 1, 2020, by and among the Company, Cantor Fitzgerald&#160;&amp; Co. and SVB Leerink LLC (incorporated by reference to our Current Report on Form 8-K filed on May 1, 2020)</span></a></td></tr>
</table>

<p style="margin: 0">&#160;</p>

<p style="margin: 0"></p>

<!-- Field: Page; Sequence: 109; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->88<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="margin: 0"></p>

<p style="margin: 0">&#160;</p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; width: 10%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">10.13</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; width: 90%; text-indent: 0pt"><a href="http://www.sec.gov/Archives/edgar/data/1314052/000173112223000152/e4385_ex10-1.htm"><span style="font: 10pt/115% Times New Roman, Times, Serif">Purchase Agreement dated February 3, 2023 by and between the Company and Lincoln Park Capital Fund, LLC (incorporated by reference to our Quarterly Report on Form 10-Q filed on February 7, 2023)</span></a></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif"><b>(14)</b></span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif"><b>Code of Ethics</b></span></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">14.1*</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="e5240_ex14-1.htm"><span style="font: 10pt/115% Times New Roman, Times, Serif">Code of Ethics Adopted on August <span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1, 2023</span></span></a></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif"><b>(21)</b></span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif"><b>Subsidiaries</b></span></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">21.1*</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="e5240_ex21-1.htm"><span style="font: 10pt/115% Times New Roman, Times, Serif">Subsidiaries of the Registrant</span></a></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif"><b>(23)</b></span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif"><b>Consent</b></span></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">23.1*</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="e5240_ex23-1.htm"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Consent of Grant Thornton LLP Independent Registered Public Accounting Firm</span></a></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt">23.2*</td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="e5240_ex23-2.htm">Consent of BDO USA,
P.C. Independent Registered Public Accounting Firm</a></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif"><b>(31) </b></span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif"><b>Section 302 Certifications</b></span></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">31.1*</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="e5240_ex31-1.htm"><span style="font: 10pt/115% Times New Roman, Times, Serif">Section 302 Certification of Christopher Missling, PhD.</span></a></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">31.2*</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="e5240_ex31-2.htm"><span style="font: 10pt/115% Times New Roman, Times, Serif">Section 302 Certification of Sandra Boenisch</span></a></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif"><b>(32) </b></span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif"><b>Section 906 Certifications</b></span></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">32.1**</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="e5240_ex32-1.htm"><span style="font: 10pt/115% Times New Roman, Times, Serif">Section 906 Certification of Christopher Missling, PhD and Sandra Boenisch</span></a></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif"><b>(97)</b></span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif"><b>Policy Relating to Recovery of Erroneously Awarded Compensation</b></span></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">97.1</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><a href="e5240_ex97-1.htm"><span style="font: 10pt/115% Times New Roman, Times, Serif">Anavex Life Sciences Corp. Compensation Clawback Policy*</span></a></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif"><b>(101)</b></span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif"><b>XBRL</b></span></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">101.INS*</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">XBRL INSTANCE DOCUMENT</span></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">101.SCH*</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">XBRL TAXONOMY EXTENSION SCHEMA</span></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">101.CAL*</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">XBRL TAXONOMY EXTENSION CALCULATION LINKBASE</span></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">101.DEF*</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">XBRL TAXONOMY EXTENSION DEFINITION LINKBASE</span></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">101.LAB*</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">XBRL TAXONOMY EXTENSION LABEL LINKBASE</span></td></tr>
<tr style="vertical-align: top; background-color: White">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">101.PRE*</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE</span></td></tr>
<tr style="vertical-align: top; background-color: rgb(204,238,255)">
<td style="padding: 0pt; line-height: 107%; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">104</span></td>
<td style="padding: 0pt; line-height: 107%; text-align: justify; text-indent: 0pt"><span style="font: 10pt/115% Times New Roman, Times, Serif">Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101)</span></td></tr>
</table>




<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="text-transform: uppercase"></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="text-transform: uppercase">&#160;</span></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt">* Filed herewith.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt">** The certification attached as Exhibit 32.1 that accompanies
this Form 10-K is not deemed filed with the SEC and is not to be incorporated by reference into any filing of the Registrant under
the Securities Act or the Exchange Act, whether made before or after the date of this Form 10-K, irrespective of any general incorporation
language contained in such filing.</p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt">&#94; Denotes a management contract or compensatory plan
or arrangement.</p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal"><span id="a_025"></span>ITEM 16. FORM
10-K SUMMARY</span></p>

<p style="font: italic bold 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font-style: normal">&#160;</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">Not Applicable.</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"></p>

<!-- Field: Page; Sequence: 110; Value: 69 -->
    <div style="border-bottom: Black 2pt solid; margin-top: 12pt; margin-bottom: 6pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->89<!-- Field: /Sequence --></td></tr></table></div>
    <div style="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%"><tr><td style="text-align: center; width: 100%">&#160;</td></tr></table></div>
    <!-- Field: /Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"></p>

<p style="font: 10pt/115% Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: center"><b>SIGNATURES</b></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="background-color: white">Pursuant
to the requirements of Section&#160;13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this report
to be signed on its behalf by the undersigned thereunto duly authorized.</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="background-color: white">&#160;</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<tr style="background-color: white">
    <td style="vertical-align: top; line-height: 107%"><span style="font: 10pt/115% Times New Roman, Times, Serif"><b>Date: November
    27, 2023</b></span></td>
    <td style="vertical-align: bottom; line-height: 107%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td colspan="3" style="vertical-align: top"><p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font: 10pt Times New Roman, Times, Serif"><b>ANAVEX
                                                LIFE SCIENCES CORP.</b></span></p></td>
    </tr>
<tr style="background-color: white">
    <td style="vertical-align: top; line-height: 107%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: bottom; line-height: 107%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td colspan="3" style="vertical-align: top"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td></tr>
<tr style="background-color: white">
    <td style="vertical-align: top; width: 50%; line-height: 107%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: bottom; width: 0%; line-height: 107%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; line-height: 107%; width: 5%"><span style="font: 10pt/115% Times New Roman, Times, Serif">By:</span></td>
    <td style="vertical-align: bottom; line-height: 107%; width: 0%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="border-bottom: Black 1pt solid; vertical-align: top; width: 45%"><p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font: 10pt Times New Roman, Times, Serif"><i>/s/
                                                                                Christopher Missling, PhD</i></span></p></td>
    </tr>
<tr style="background-color: white">
    <td style="vertical-align: top; line-height: 107%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: bottom; line-height: 107%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; line-height: 107%"><span style="font: 10pt/115% Times New Roman, Times, Serif">Name:</span></td>
    <td style="vertical-align: bottom; line-height: 107%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; line-height: 107%"><span style="font: 10pt/115% Times New Roman, Times, Serif">Christopher
    Missling, PhD</span></td>
    </tr>
<tr style="background-color: white">
    <td style="vertical-align: top; line-height: 107%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: bottom; line-height: 107%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: top; line-height: 107%"><span style="font: 10pt/115% Times New Roman, Times, Serif">Title:</span></td>
    <td style="vertical-align: bottom; line-height: 107%"><span style="font: 10pt Times New Roman, Times, Serif">&#160;</span></td>
    <td style="vertical-align: bottom"><p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><span style="font: 10pt Times New Roman, Times, Serif">Chief
                                       Executive Officer (Principal Executive Officer)&#160;</span></p></td>
    </tr>
</table>


<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="background-color: white">&#160;</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="background-color: white">Pursuant
to the requirements of the Securities Exchange Act of 1934, this report has been signed below by the following persons on behalf
of the registrant and in the capacities and on the dates indicated.</span></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"></p>

<table cellspacing="0" cellpadding="0" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<tr style="vertical-align: bottom">
<td style="border-bottom: Black 1pt solid; text-align: center; white-space: nowrap"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Signatures</b></span></td>
<td style="padding-bottom: 1pt; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: center; white-space: nowrap"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Title(s)</b></span></td>
<td style="padding-bottom: 1pt; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: center; white-space: nowrap"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Date</b></span></td></tr>
<tr style="vertical-align: bottom">
<td style="white-space: nowrap"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="white-space: nowrap"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="white-space: nowrap; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom">
<td style="border-bottom: Black 1pt solid"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>/s/ Christopher
Missling, PhD</i></span></td>
<td style="line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="line-height: 107%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">November 27,
2023</span></td></tr>
<tr>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Christopher
Missling, PhD</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Chief
Executive Officer (Principal Executive Officer) and Director</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="line-height: 107%; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr>
<td style="vertical-align: top; line-height: 107%">&#160;</td>
<td style="vertical-align: bottom; line-height: 107%">&#160;</td>
<td style="vertical-align: top; line-height: 107%">&#160;</td>
<td style="vertical-align: bottom; line-height: 107%">&#160;</td>
<td style="line-height: 107%; font-size: 10pt; text-align: center">&#160;</td></tr>
<tr>
<td style="border-bottom: Black 1pt solid; vertical-align: top; width: 29%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>/s/
Sandra Boenisch</i></span></td>
<td style="vertical-align: bottom; width: 1%; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; width: 47%; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; width: 1%; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; width: 22%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">November 27,
2023 &#160;</span></td></tr>
<tr>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Sandra
Boenisch, CPA, CGA</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Principal
Financial Officer and Treasurer (Principal Accounting Officer)</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="line-height: 107%; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr>
<td style="vertical-align: top; line-height: 107%">&#160;</td>
<td style="vertical-align: bottom; line-height: 107%">&#160;</td>
<td style="vertical-align: top; line-height: 107%">&#160;</td>
<td style="vertical-align: bottom; line-height: 107%">&#160;</td>
<td style="line-height: 107%; font-size: 10pt; text-align: center">&#160;</td></tr>
<tr>
<td style="border-bottom: Black 1pt solid; vertical-align: top"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>/s/
Jiong Ma, PhD</i></span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">November 27, 2023 &#160;</span></td></tr>
<tr>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Jiong
Ma, PhD</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Director,
Chair</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr>
<td style="border-bottom: Black 1pt solid; vertical-align: top"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>/s/
Athanasios Skarpelos</i></span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">November 27, 2023 &#160;</span></td></tr>
<tr>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Athanasios
Skarpelos</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Director</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="line-height: 107%; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="line-height: 107%; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr>
<td style="border-bottom: Black 1pt solid; vertical-align: top"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>/s/
Claus van der Velden, PhD</i></span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">November 27, 2023 &#160;</span></td></tr>
<tr>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Claus
van der Velden, PhD</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Director</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="line-height: 107%; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="line-height: 107%; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr>
<td style="border-bottom: Black 1pt solid; vertical-align: top"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>/s/
Steffen Thomas, PhD</i></span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">November 27, 2023 &#160;</span></td></tr>
<tr>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Steffen
Thomas, PhD</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Director</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr>
<td style="border-bottom: Black 1pt solid; vertical-align: top"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><i>/s/
Peter Donhauser, D.O.</i></span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: bottom; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">November 27, 2023 &#160;</span></td></tr>
<tr>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Peter
Donhauser, D.O.</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 115%">Director</span></td>
<td style="vertical-align: bottom; line-height: 107%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="vertical-align: top; line-height: 107%; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center; background-color: white"><span style="font: 10pt Times New Roman, Times, Serif">90</span></p>

<!-- Field: Rule-Page --><div style="margin-top: 3pt; margin-bottom: 3pt; width: 100%"><div style="border-top: Black 2pt solid; font-size: 1pt">&#160;</div></div><!-- Field: /Rule-Page -->

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"></p>

<p style="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&#160;</p>



<p style="margin: 0"></p>

</body>
</html>
<!-- Field: Set; Name: xdx; ID: xdx_08B_extensions -->
<!--   -->
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-14.1
<SEQUENCE>2
<FILENAME>e5240_ex14-1.htm
<DESCRIPTION>EXHIBIT 14.1
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0"></P>

<!-- Field: Rule-Page --><DIV ALIGN="LEFT" STYLE="margin-top: 10pt; margin-bottom: 3pt"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid; width: 100%">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0">&nbsp;&nbsp;</P>

<P STYLE="margin: 0; text-align: right"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>EXHIBIT 14.1</B></FONT></P>

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><FONT STYLE="color: black">&nbsp;</FONT>BUSINESS
CODE OF CONDUCT &amp; ETHICS</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">I.</FONT></TD><TD STYLE="text-align: justify"><U>INTRODUCTION/PURPOSE</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">As a business engaged in
the discovery, development and commercialization of medicines for the treatment of various diseases, Anavex<SUP>TM</SUP> Life Sciences
Corp. (the &ldquo;<B>Anavex</B>&rdquo; or the &ldquo;<B>Company</B>&rdquo;) must always act in a way that reflects the highest
standards of corporate behavior and conduct itself in a legal and ethical manner. Each of us must always exercise good judgment
and common sense in making the necessary choices to advance the interests of the Company. The development and maintenance of relationships
of trust between each of us and government officials, health care professionals, patients, suppliers, customers, investors and
other employees is essential and expected. Obeying the law both in letter and in spirit is the foundation on which Anavex&rsquo;s
ethical standards are built. In carrying out this policy, Anavex has adopted the following Business Code of Conduct and Ethics
(the &ldquo;<B>Code</B>&rdquo;). This Code is intended to cover Anavex&rsquo;s and its affiliates&rsquo; directors, officers and
employees, as well agents and other parties acting on behalf, or for the benefit, of the Company and/or its affiliates (collectively,
&ldquo;<B>Covered Persons</B>&rdquo;).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Each Covered Person plays
an important role in the Company&rsquo;s achievements. The Company is dedicated to its mission and preserving its reputation of
integrity in all the business it does. Anavex believes that building and maintaining a culture of compliance is integral to its
success and requires the cooperation and commitment of each Covered Person.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">This Code is designed to
define the Company&rsquo;s general expectations for legal and ethical business behavior for all Covered Persons. The Code is a
guide and may not address every legal or ethical issue nor is it an exhaustive description of all laws and policies that may apply
to our business. It is a statement of the Company&rsquo;s expectations and obligations.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company views this Code
very seriously and expects all Covered Persons to abide by it. Any Covered Person who violates the standards set forth in the Code
may be subject to disciplinary action which, depending on the nature of the violation and the history of the Covered Person, may
range from a warning to a termination of employment and in appropriate cases, civil legal action or referral for regulatory or
criminal prosecution.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Understanding and daily
application of the principles of the Code provides a basis for making the right decisions for the Company; by embracing core values,
the Company creates a productive and respectful work environment poised to contribute to global healthcare. Each of us is responsible
for becoming familiar and following all the rules, regulations and policies that apply to our jobs and for seeking advice in any
situation where we are unsure of what to do.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">II.</FONT></TD><TD STYLE="text-align: justify"><U>RESPONSIBILITIES</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Each Covered Person is expected
(i) to read and understand this Code which provides general principles to guide Covered Persons in making ethical decisions, and
its application to the performance of his or her business responsibilities and (ii) to conduct himself or herself in accordance
with this Code and to seek to avoid even the appearance of wrongdoing or improper behavior. Those who violate the standards in
this Code will be subject to disciplinary action, which may include suspension, termination and/or the reporting of violative conduct
to appropriate regulatory and criminal authorities. Any director, officer, or employee who observes or otherwise becomes aware
of conduct that violates, or could violate, the Code must take a prompt report of such violation to the Company. Any officer or
employee who fails to immediately report a Code violation, or perceived violation, or who violates any aspect of the Code may be
subject to disciplinary action, up to and including termination of employment.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">If a law conflicts with
a policy in this Code, a Covered Person must comply with the law; however, if a local custom or policy conflicts with this Code,
a Covered Person must comply with this Code. If a Covered Person has any questions about these conflicts or this Code, he or she
should consult with the Chief Executive Officer (&ldquo;<B>CEO</B>&rdquo;).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 13.5pt; text-align: justify; text-indent: 36pt">The Company strongly
encourages dialogue among Covered Persons should awareness of situations that give rise to ethical questions transpire; Covered
Persons should discuss and articulate acceptable ways of handling those situations with the CEO. The Company shall provide a copy
of this Code to all new hires and, upon a change to the Code, to all current employees. Additionally, the Company shall also provide
its employees with periodic compliance training as a supplement this Code of Conduct.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 13.5pt; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 13.5pt; text-align: justify; text-indent: 36pt"></P>

<!-- Field: Page; Sequence: 1; Options: NewSection -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 13.5pt; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 13.5pt; text-align: justify; text-indent: 0cm">The Company shall
take reasonable steps to monitor and audit compliance with the Code of Conduct, including the establishment of monitoring and auditing
systems that are reasonably designed to detect violations of the Code of Conduct. Additionally, the Company will periodically review
the Code of Conduct, and when necessary or desirable, make recommendations to ensure:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 13.5pt; text-align: justify; text-indent: 0cm">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">its continued conformance to applicable law,</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">that it meets or exceeds industry standards, and</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">that any weaknesses revealed through monitoring, auditing and reporting systems are eliminated
or corrected. The Company may revise, change or amend the Code of Conduct, or any policies or procedures, at any time.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">After carefully reviewing
this Code, you must sign the acknowledgment attached hereto, indicating that you have received, read, understand and agree to comply
with this Code. The acknowledgment must be returned either electronically in a manner provided for by the Company within ten (10)
business days of your receipt of this Code and otherwise as required by the Company. All Covered Persons will each be required
to annually certify compliance with the Code. The failure to certify such compliance or any false certification, even if directed
by a supervisor, is grounds for disciplinary action by the Company, up to and including termination of employment.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">III.</FONT></TD><TD STYLE="text-align: justify"><U>HONEST AND ETHICAL CONDUCT</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Each Covered Person must
always conduct himself or herself in an honest and ethical manner. Each Covered Person must act with the highest standards of personal
and professional integrity and not tolerate others who attempt to deceive or evade responsibility for their actions. All actual
or potential conflicts of interest between personal and professional relationships must be handled honestly, ethically and in accordance
with the policies specified in this Code. In addition, all Covered Persons must be direct, honest and truthful in discussions with,
or requests for information from, the Board, regulatory agency officials and government officials, as well as in all dealings with
business partners and shareholders. Every Covered Person is accountable for adhering to the Company&rsquo;s commitment to conduct
its business fairly, honestly and with integrity.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">IV.</FONT></TD><TD STYLE="text-align: justify"><U>COMPLIANCE WITH APPLICABLE GOVERNMENTAL LAWS, RULES AND REGULATIONS</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">All Covered Persons must
respect and obey the laws, rules and regulations (including insider trading laws) of the jurisdictions in which we operate and
the rules and regulations applicable to the Company, its business and its affiliates (collectively, the &ldquo;<B>Company Group</B>&rdquo;),
including those of the NASDAQ and the Securities and Exchange Commission (the &ldquo;<B>SEC</B>&rdquo;). The Company shall hold
periodic training sessions to ensure all employees are aware of and comply with the relevant laws, rules and regulations associated
with their employment. Although not all Covered Persons are expected to know the details of the laws, rules and regulations to
which the Company Group is subject, it is important to understand enough to determine when it is necessary or appropriate to seek
advice from supervisors, managers or other persons, including the CEO and/or Board of Directors (&ldquo;<B>Board</B>&rdquo;), who
can provide guidance on such matters.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Disregard of the law will
not be tolerated. Violation of any applicable laws, rules and regulations may subject an individual, as well as one or more members
of the Company Group, to civil, administrative and/or criminal penalties and may harm their reputations. Covered Persons should
be aware that conduct and records, including e-mails, are subject to internal and external audits and to discovery by third parties
in the event of a government investigation or civil litigation. Consequently, it is in everyone&rsquo;s best interest to understand
and comply with the laws, rules and regulations applicable to the Company Group.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify">Areas that require particular attention
to ensure proper compliance include:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">Antitrust and Competition Laws: It is the policy of the Company to comply with the antitrust and
competition laws of each country in which the Company does business. No director, officer or employee of the Company will engage
in anti-competitive conduct in violation of any antitrust or competition law.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt"></P>

<!-- Field: Page; Sequence: 2 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">Intellectual Property Laws: The Company requires that all scientific and technical information
generated, utilized and maintained by its employees and in strict compliance and conformity with applicable intellectual property
laws.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">Workplace Safety Laws and Regulations: The Company requires full compliance with applicable workplace
safety and industrial hygiene standards required by law. Each of us has a responsibility for maintaining a safe and healthy working
environment for all persons at the Company, following safety and health rules and practices and reporting accidents, injuries and
unsafe equipment, practices or conditions.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">Insider Trading Laws: All members of board of directors and of executive boards, and their auxiliary
staff in the Company Group, will be severely penalized if they make use of &#8220;hot information&#8221; (i.e. information that
is not available to the general public, facts which could substantially influence the price of a listed security) that is in their
possession to create a financial advantage for themselves or for some third party by purchasing (prior to the announcement of favorable
information) or selling (prior to the announcement of unfavorable information) stock that is listed on an exchange or other securities.
The insider trading provisions affect securities of Anavex Life Sciences Corp., and those of companies that are being acquired
or merged with Anavex or a Company with which Anavex is planning to enter into a strategic alliance, if the said securities are
listed on an exchange or traded in pre-market dealings.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">Privacy and Data Protection Laws: The Company is committed to the protection of the individual
privacy of employees, persons who participate in the clinical trials of the Company&#8217;s drug candidates and products and individual
third parties who perform services on behalf of the Company. The Company must comply with applicable privacy laws and regulations
whenever the Company does business, including activities performed on behalf of the Company by third parties. Such laws and regulations
are complex and differ from country to country. Any employee who handles or oversees the handling of individually-identifiable
data and who has a concern or question about the proper handling of such data should contact the CEO and/or consult any applicable
Company policies.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">Laws and Regulations relating to Records Retention: The Company must comply with all laws and regulations
mandating specified time periods for retaining various records of Company&#8217;s activities. It is the responsibility of each
direct report of the CEO working with his/her staff and the CEO, to establish and maintain a system for the retention and safekeeping
of all records that are required by law or Company Policy.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">Laws Governing Pharmaceutical Products: The Company must comply with all laws and regulations governing
the manufacture, testing, review and approval, sales, marketing, shipment, storage, and destruction of pharmaceutical products
set forth by the Food and Drug Administration, the Drug Enforcement Administration, the local authorities and the European Union
and its member states. In conducting clinical trials of pharmaceutical products, the Company will comply with rules governing human
subject protection, animal welfare, and public disclosure of clinical trials for serious and life threatening diseases. The distribution
of pharmaceutical samples must comply with the Prescription Drug Marketing Act. These laws and regulations are complex, technical,
and comprehensive. Therefore, all employees shall take steps to become familiar with those areas directly relevant to their responsibilities
and shall consult with the CEO to obtain guidance on issues or areas of law or regulation that might arise during the normal course
of business.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">Interacting with healthcare professionals: All employees, officers and directors must comply with
all applicable laws, regulations and professional ethical rules in their dealing with healthcare professionals. The purpose of
every interaction between the Company and a healthcare professional must be to benefit patients or enhance the practice of medicine.
You may inform healthcare professionals about Company products, provide scientific and medical information and promote medical
research.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">Responsibility of Company Personnel: Every director, officer, or employee has the responsibility
to report a violation or suspected violation of this Policy. The Company promptly responds to all reports of suspected violations.
Any Director, officer, or employee who knows or believe that any other Director, officer, or employee of the Company, or anyone
else representing the Company, is violating or is suspected of violating this Policy should contact his supervisor or the CEO.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt"></P>

<!-- Field: Page; Sequence: 3 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">V.</FONT></TD><TD STYLE="text-align: justify"><U>CONFLICT OF INTEREST</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">All Covered Persons have
a duty to avoid business, financial or other direct or indirect relationships that conflict with the interests of the Company or
that divide his or her loyalty to the Company. A conflict of interest occurs when your personal interest interferes or appears
to interfere with the interests of the Company, or the Company Group as a whole. A conflict situation can arise, for example, when
a Covered Person takes actions or has interests that may make it difficult to perform his or her work for the Company honestly,
objectively and fairly. It is almost always a conflict for a Company officer or employee to work simultaneously for a competitor,
customer, or supplier or to work for a competitor as a consultant or board member. Conflicts of interest also arise when a Covered
Person, or any Family Member (as defined below) of such person, receives improper personal benefits as a result of his or her position
at the Corporation. Loans to, other than those made in the ordinary course of business, or guarantees of obligations of, employees
or their Family Members may also create a conflict of interest. Covered Persons may not participate in a joint venture, partnership
or other business arrangement with the Company, without the prior approval of a majority of the Board.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Any activity which even
appears to present a conflict must be avoided or terminated unless, after disclosure to the Company, it is determined that the
activity is not harmful to the Company or otherwise improper. It is our responsibility to disclose any material transaction or
relationship that could be expected to give rise to a conflict of interest to the CEO or Board of Directors. Managers may not authorize
conflict of interest matters or make determinations as to whether a problematic conflict of interest exists without first seeking
the approval of the CEO including a written description of the activity. Officers and directors may seek authorizations and determinations
from the Nominating and Corporate Governance Committee of the Board of Directors.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">For purposes of this Code,
&ldquo;Family Member&rdquo; generally means a person&rsquo;s spouse, parents, children and siblings, whether by blood, marriage
or adoption, or anyone residing in such person&rsquo;s home.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">VI.</FONT></TD><TD STYLE="text-align: justify"><U>CORPORATE OPPORTUNITIES</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Covered Persons owe a duty
to the Company Group to advance their legitimate interests when the opportunity to do so arises. Covered Persons must offer to
the Company any business opportunities related to the Company Group&rsquo;s target assets and business activities (as described
in the Company&rsquo;s Registration Statement on Form S-1 relating to the Company&rsquo;s initial public offering or any periodic
report filed by the Company from time to time with the SEC, together with any other assets that the Board determinates from time
to time will be a target asset or potential investment or business of the Company Group). Covered Persons are prohibited from:
(i) taking for themselves opportunities that are discovered through the use of Company Group property, information or position,
unless such opportunities are presented to the Board and the Board declines to pursue such opportunities; (ii) using Company Group
property, information or position for improper personal gain; or (iii) competing with any member of the Company Group. Any employee,
other than an officer, may only pursue a corporate opportunity if the CEO or Board waives in writing the Company&rsquo;s right
to pursue the corporate opportunity. Corporate opportunities available to directors and officers may only be waived by the Board.
If the Company waives its right to pursue a corporate opportunity, Covered Persons may pursue such opportunities in a manner consistent
with this Code.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">VII.</FONT></TD><TD STYLE="text-align: justify"><U>COMPLIANCE PROCEDURES; REPORTING VIOLATIONS</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">As part of its commitment
to ethical and legal conduct, Covered Persons must bring to attention information about suspected or known violations of law or
policy by any employee, contractor or agent of the Company to the CEO or an appropriate manager. Violations should be reported
regardless of the identity or position of the person suspected of engaging in improper conduct. The Company expects all Covered
Persons to work to ensure prompt and consistent action against violations of this Code. This Code covers a wide range of business
practices and procedures, but it does not address every applicable law or respond to every ethical question or concern that may
arise. Nonetheless, the general guidelines of this Code provide each Covered Person with the Company&rsquo;s expectations regarding
business dealings. The Company understands that there may be some situations in which it is difficult to know right from wrong.
In determining the best course of action, each Covered Person should answer the following questions to help evaluate specific situations:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt">1.</TD><TD STYLE="text-align: justify">Will my action comply with the intent and purpose of the Company&rsquo;s policies and practices?</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt"></P>

<!-- Field: Page; Sequence: 4 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt">2.</TD><TD STYLE="text-align: justify">Will I compromise myself or the reputation of any member of the Company Group by this action if
it becomes known to my supervisor, colleagues, shareholders or friends?</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt">3.</TD><TD STYLE="text-align: justify">Is this action honest in every respect?</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt">4.</TD><TD STYLE="text-align: justify">Could this action appear inappropriate to others, even if it is ethical?</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">If something you have seen,
heard or been asked to do (or not do) seems illegal, unethical or improper, it may very well be. Each Covered Person should use
his or her judgment before taking any action that could be deemed a violation of this Code or any law, rule or regulation or Company
policy. Furthermore, any Covered Person who becomes aware of (a) any existing or potential violation of this Code or any law, rule
or regulation or Company policy or (b) alleged irregularities of a general, operational or financial nature within the Company
(&ldquo;<B>Alleged Irregularities</B>&rdquo;), has an obligation to report his or her complaint or concern to his or her supervisor,
to the CEO, the Whistleblower Hotline or the Board. Alleged Irregularities concerning the functioning of the Board may be reported
directly to the CEO.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">No Covered Person should
report any existing or potential violation of the Code or any law, rule or regulation, Company policy or any Alleged Irregularity
to any person who is involved in the matter giving rise to the existing or potential violation.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">All concerns will be taken
seriously by the Company and, when appropriate, the Company will fully investigate each allegation. This may include talking to
any individuals directly involved, as well as to others who may possess information pertinent to the situation. Covered Persons
are expected to cooperate fully with internal investigations of wrongdoing or misconduct, and failure to cooperate fully with any
such investigations will lead to disciplinary action, up to and including termination.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company will not tolerate
any retaliation against any Covered Person for raising, in good faith, a possible violation of this Code or of a law, rule or regulation,
Company policy or any Alleged Irregularity. Retaliation for reporting a U.S. federal offense is illegal under U.S. federal law.
Any person who participates in retaliatory conduct will be subject to disciplinary action up to and including termination of employment
or office. Misusing this Code by knowingly or recklessly providing false information to the Company may also result in appropriate
disciplinary action. Any Covered Person who deliberately fails to report a matter of noncompliance will be subject to appropriate
disciplinary action.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Every director, officer,
manager and supervisor who receives a complaint or a report alleging or regarding an actual or potential violation of this Code
or of a law, rule or regulation, Company policy or regarding any Alleged Irregularity, has, without exception, the responsibility
to immediately communicate such complaint to the CEO.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Adherence to this Code is
a condition of working for the Company. If, after investigation, it is determined that a compliance violation has occurred, an
employee may be subject to discipline including, for example, training, referral to counseling, warning, reprimand, withholding
of a promotion or pay increase, demotion, reassignment, temporary suspension without pay, or termination of employment.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">VIII.</FONT></TD><TD STYLE="text-align: justify"><U>ACCOUNTING COMPLAINTS</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company&rsquo;s policy
is to comply fully with all applicable financial reporting and accounting regulations. If any Covered Person has unresolved concerns
or complaints regarding questionable accounting, internal control or auditing matters concerning the Company, such person is encouraged
to submit such concerns or complaints in accordance with the Company&rsquo;s Complaint Procedures.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">IX.</FONT></TD><TD STYLE="text-align: justify"><U>FAIR DEALING</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">We seek to outperform our
competition fairly and honestly. We seek competitive advantages through superior performance, never through unethical or illegal
business practices. Stealing proprietary information, possessing trade secret information that was obtained without the owner&rsquo;s
consent, or inducing such disclosures by past or present employees or officers of other companies is prohibited. Each Covered Person
should endeavor to respect the rights of, and to deal fairly with the Company Group&rsquo;s guests, suppliers, consultants, competitors,
employees, officers and other persons with whom the members of the Company Group transact business. No Covered Person should take
unfair advantage of anyone through manipulation, concealment, abuse of privileged information, misrepresentation of material facts,
or any other unfair dealing practice.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"></P>

<!-- Field: Page; Sequence: 5 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">X.</FONT></TD><TD STYLE="text-align: justify"><U>CONFIDENTIALITY</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Directors, officers and
employees should maintain the confidentiality of information entrusted to them by the Company, except when disclosure is authorized
under the Company&rsquo;s Disclosure Policy or as otherwise legally mandated. Confidential information includes all non-public
information that might be of use to competitors, or harmful to the Company, its suppliers or its customers, if disclosed. It also
includes information that suppliers, customers and individuals or institutions involved in clinical trials or other product development
activities have provided to the Company. Employees should take appropriate steps to limit distribution of such confidential information
to only those employees of the Company who have a need to know such information in order to carry out their job responsibilities.
It is the Policy of the Company that each of us must respect the proprietary information of other individuals or organizations
with which the Company does business. Information obtained from public sources can legitimately be used in the Company&rsquo;s
business activities, but proprietary information obtained through improper means can never be used by any director, officer or
employee in carrying out his /her job responsibilities.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XI.</FONT></TD><TD STYLE="text-align: justify"><U>NO ABUSE OF CORPORATE ASSETS</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Employees may not take personal
advantage of opportunities that are presented to them or discovered by them as a result of their position with the Company or through
their use of corporate property or information, unless authorized by the Board of Directors. Even opportunities that are acquired
privately by the employee may be questionable if they are related to the Company&rsquo;s existing or proposed lines of business.
Significant participation in an investment or outside business opportunity that is directly related to our lines of business must
be pre-approved. Employees may not use their position at the Company or corporate property or information for improper personal
gain, nor should they compete with the Company in any way.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XII.</FONT></TD><TD STYLE="text-align: justify"><U>MEDIA/PUBLIC DISCLOSURES</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">It is our policy to disclose
material information concerning the Company and its work to the public only through specific limited channels to avoid inappropriate
or inaccurate publicity. Employees may not provide any information to the media about the Company and its work or customers, whether
off-the-record, for background only, confidentially or secretly. All inquiries or calls from the press should be referred to the
CEO.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XIII.</FONT></TD><TD STYLE="text-align: justify"><U>PROTECTED INFORMATION</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company believes in
the importance of respecting the privacy of all of those with whom we do business. During normal business activities, the Company
may collect personal, sensitive or nonpublic information about various individuals, including our employees, customers, patients,
clinical trial participants and others with whom we conduct business. It is the Company&rsquo;s policy to respect the privacy and
guard the confidentiality of personal, sensitive or nonpublic information, including protected health information. Accordingly,
employees must maintain and use such information in accordance with the law, and the Company&rsquo;s even more stringent policies
and procedures. The Company will implement measures designed to protect the personal, sensitive or nonpublic information and to
appropriately maintain a system for protection of that information.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Patient personal data, including
Protected Health Information (PIH) and sensitive personal data may be subject to additional regulatory protections, such as a requirement
to have policy and security safeguards in place to protect it. We are responsible for ensuring that patient personal data is kept
secure and confidential and used solely for the purpose for which it was collected. Employees responsible for handling such patient
data are expected to become familiar with laws and regulations in the jurisdictions in which we conduct clinical trials.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XIV.</FONT></TD><TD STYLE="text-align: justify"><U>INSIDER TRADING</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The laws against insider
trading of the Company&rsquo;s (or other) securities are specific and complex. Covered Persons may obtain, or come into regular
or occasional contact with, information that qualifies as &ldquo;inside information&rdquo; under applicable securities laws. Inside
information includes material information about the Company that is not available to the public. The unauthorized use by a Covered
Person of inside information is unethical and may also be unlawful. Covered Persons should never trade the shares or other securities
of the Company while in possession of inside information, nor should they disclose such information to any other person that might
engage in trading activities, unless in compliance with the Company&rsquo;s Policy on Insider Information and Insider Trading.
In all cases, it is each Covered Person&rsquo;s responsibility to ensure that he or she complies with all relevant securities laws
and regulations.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"></P>

<!-- Field: Page; Sequence: 6 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XV.</FONT></TD><TD STYLE="text-align: justify"><U>SOCIAL MEDIA</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company recognizes the
popularity of social media as a business tool in appropriate circumstances and has implemented a policy outlining the use of social
media in its Employee Handbook. Business and personal use of social media relating to the Company, its business or its employees,
whether on or off working time or Company equipment, must comply with the Company&rsquo;s Employee Handbook.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XVI.</FONT></TD><TD STYLE="text-align: justify"><U>PROTECTION AND PROPER USE OF THE COMPANY GROUP&rsquo;S ASSETS </U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">All Covered Persons should
protect the Company Group&rsquo;s assets and ensure their efficient use. Theft, carelessness and waste have a direct impact on
the Company Group&rsquo;s profitability. Any suspected incident of fraud or theft should be immediately reported to the Company&rsquo;s
CEO or designee. All of the Company Group&rsquo;s assets should be used for legitimate business purposes and should not be used
for non-company business, although incidental personal use may be permitted with the permission of your supervisor. The Company
has the ability, and reserves the right, to monitor all electronic and telephonic communication.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XVII.</FONT></TD><TD STYLE="text-align: justify"><U>BUSINESS RECORDS</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company has a responsibility
to ensure that it provides the investing public with information that accurately and fairly reflects the true value of its operations.
Accurate and fair records are essential to ensure the proper conduct of the Company&rsquo;s business and its compliance with the
law.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company&rsquo;s responsibilities
to its stakeholders and the investing public require that all of the Company&rsquo;s and Company Group&rsquo;s books, records,
accounts and financial statements be maintained in reasonable detail, appropriately reflect the Company&rsquo;s transactions and
conform to applicable legal requirements, the Company&rsquo;s system of internal controls and generally accepted accounting principles
(&ldquo;<B>GAAP</B>&rdquo;). The Company relies on the accuracy and completeness of its business records to (i) provide full, fair,
accurate, timely and understandable disclosure in the current reports, periodic reports and other information it files with or
submits to the SEC and in other public communications, such as press releases, earnings conference calls and industry conferences,
made by the Company or on the Company&rsquo;s behalf, (ii) make management decisions and (iii) analyze its operations. The accuracy
of such records is essential for continued, long-term business success.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">No false, misleading or
artificial entries may be made by any Covered Person in the books and records of the Company or the Company Group. All Covered
Persons with supervisory responsibility shall establish and implement appropriate internal accounting controls over all areas of
their responsibility to ensure the safeguarding of the Company&rsquo;s assets and the accuracy of its financial records and reports.
The Company has adopted controls in accordance with internal needs and the requirements of applicable laws and regulations. These
established accounting practices and procedures must be followed to assure the complete and accurate recording of all transactions.
All Covered Persons, within their areas of responsibility, are expected to adhere to these procedures, as directed by the Chief
Financial Officer.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">We all share the responsibility
of maintaining accurate records and reports. Even if you are not directly involved in financial reporting or accounting, you are
likely involved with financial records or reports of some kind&mdash;a contract, time sheet, invoice or expense report. In addition,
most employees have involvement with product or administrative activities or performance evaluations, which can affect our reported
financial condition or results. Therefore, regardless of whether you are otherwise required to be familiar with finance or accounting
matters, you are required to use all reasonable efforts to ensure that every business record or report with which you deal is accurate,
complete and reliable</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Any accounting adjustments
that materially depart from GAAP must be approved by the Company&rsquo;s Chief Financial Officer. In addition, all material off-balance-sheet
transactions, arrangements and obligations, contingent or otherwise, and other relationships of the Company with unconsolidated
entities or other persons that may have material current or future effects on the financial condition, changes in financial condition,
results of operations, liquidity, capital expenditures, capital resources or significant components of revenues or expenses must
be disclosed to the Company&rsquo;s Chief Financial Officer.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"></P>

<!-- Field: Page; Sequence: 7 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Audit Committee plays
an important role in ensuring the integrity of our public reports. If you believe that questionable accounting or auditing conduct
or practices have occurred or are occurring, you should notify the Audit Committee of the Board of Directors. In particular, our
CEO and senior financial officers should promptly notify the Audit Committee any such information of which he or she may become
aware including the accuracy of material disclosures in public filings, material weaknesses or significant deficiencies in internal
controls over financial reporting and any evidence of fraud that involves an employee with a significant role in our financial
reporting disclosures or internal controls or procedures.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">No Covered Person may interfere
with or seek to improperly influence, directly or indirectly, the auditing of the Company&rsquo;s financial records. Violation
of these provisions shall result in disciplinary action, up to and including termination of employment, and may also subject the
violator to substantial liability.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XVIII.</FONT></TD><TD STYLE="text-align: justify"><U>RECORDS MANAGEMENT</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company has implemented
measures to ensure that its records will be appropriately safeguarded. The Company&rsquo;s employees will retain records for as
long as they are required and in the manner required to meet its legal, regulatory, administrative and operational requirements,
after which they may be appropriately discarded. In many instances, there are legal requirements that certain records be retained
for specific periods of time and may be appropriately disposed of once that period of time has elapsed. Records necessary for business
reasons will be retained for a period of time that will reasonably assure the availability of those records when needed. Whenever
it becomes apparent that records of any type will be required in connection with a lawsuit or government investigation, all relevant
records should be preserved, and ordinary disposal or alteration of records pertaining to the subject of the litigation or investigation
should be suspended. If an employee is uncertain whether records under his or her control should be preserved because they might
relate to a lawsuit or investigation, he or she should contact the CEO.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XIX.</FONT></TD><TD STYLE="text-align: justify"><U>DISCLOSURE OF COMPANY INFORMATION</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Information is a valuable
corporate asset. Open and effective dissemination of information is critical to the Company&rsquo;s success. However, much of the
information to which Covered Persons have access at the Company is confidential and/or proprietary. Confidential information is
information that the Company considers private and that is not common knowledge outside the Company. Proprietary information is
information the Company owns, develops, pays to have developed, or to which it has an exclusive right. Because the disclosure of
such information could seriously damage the Company&rsquo;s interests, safeguarding this information is the responsibility of all
employees of the Company and Covered Persons. Each employee and Covered Person must safeguard all confidential and proprietary
information. Covered Persons will not, without prior written approval of the Company, disclose information that has not already
been published or made publicly available.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Covered Persons may not
share proprietary information with anyone not entitled to know for a legitimate business reason including fellow employees, spouses,
other family members, and friends. Any access to confidential and proprietary information given to a third-party (outside of the
Company) for a legitimate business reason must be provided under a confidentiality agreement approved by the CEO with the advice
of legal counsel. Covered Persons will exercise due care to prevent the release or sharing of information beyond those people who
need to know such information to perform their job function. To avoid inadvertent disclosure of such information, you will avoid
discussions of Company information in public places such as elevators, public transportation, restaurants or on public telephones.
Only the CEO may respond to the media, the financial community or other outside inquiries about the Company. The obligation to
protect the Company&rsquo;s Confidential and proprietary information continues even if employment with the Company ends.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Additionally, a substantial
part of the Company&rsquo;s business involves use and licensing of patents, trademarks, copyrights and use of rights licensed from
others. The Company and its business partners invest extraordinary expertise and resources to make their products, and they expect
their intellectual property to be respected and protected. The confidentiality of the Company&rsquo;s intellectual property is
critical to the success of our business and must be strictly maintained. Similarly, Company employees and Covered Persons should
never take or accept from others information or materials known or believed to contain the trade secrets of a competitor.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"></P>

<!-- Field: Page; Sequence: 8 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XX.</FONT></TD><TD STYLE="text-align: justify"><U>PROPER USE OF COMPANY PROPERTY</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">All Covered Persons are
expected to protect the Company&rsquo;s assets and use them appropriately and efficiently. Theft, carelessness, and waste have
a direct impact on profitability. The Company property, such as office and lab supplies, computer equipment, and facilities are
expected to be used only for legitimate business purposes, although incidental personal use may be permitted. Employees may not,
however, use the Company&rsquo;s name, any brand name or trademark owned or associated with the Company or letterhead stationery
for any personal purpose. Any misuse or suspected misuse of the Company&rsquo;s assets must be immediately reported to the CEO.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Theft of any Company equipment,
property or funds, including without limitation, the submission of inappropriate or fraudulent requests for reimbursement of expenses,
will not be tolerated.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XXI.</FONT></TD><TD STYLE="text-align: justify"><U>USE OF COMPANY EQUIPMENT, VOICE MAIL AND E-MAIL</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Technology is critical to
our success at the Company. Everyone who uses our technology in the course of their employment has the responsibility to use the
resources provided appropriately and securely. You will only use e-mail, voice mail systems, and other Company equipment (e.g.,
laptop computers, servers) for conducting business or for other purposes authorized by your supervisor. Reasonable, limited personal
use of these systems and equipment is permissible; however, you will not use these systems or equipment in connection with any
inappropriate or offensive material, including without limitation any pornographic or obscene material. The Company may monitor
and audit all usage of these systems and equipment to ensure integrity and to prevent misuse. There shall be no expectation of
privacy in your use of these systems or equipment.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XXII.</FONT></TD><TD STYLE="text-align: justify"><U>QUALITY PRODUCTS AND PATIENT SAFETY</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company is committed
to carefully assessing the risks and benefits of our products before and after we bring them to market. We understand that it is
critical for patients and physicians to understand these risks and benefits before making treatment decisions, and the responsibility
of providing accurate product information is one the Company takes very seriously.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company conducts and
supports new medical research and recognizes that clinical trial and other research findings are an important means of adding to
the medical community&rsquo;s body of knowledge. The Company strives to make all clinically significant scientific information
resulting from our clinical trials and other research publicly available and to ensure that any publications resulting from research
financially supported by the Company accurately disclose the Company&rsquo;s support.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company collaborates
with appropriate regulatory authorities to determine the label information for each of our products in an effort to ensure that
accurate and complete information about the indications and safety of our products is provided.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">A.</FONT></TD><TD STYLE="text-align: justify"><U>COMMITMENT TO QUALITY</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company is committed
to developing and manufacturing the highest quality products in accordance with all relevant laws. Our dedication to quality is
the driving force of what we do for patients and for our Company. By focusing on quality in all internal and contracted operations
that support the development of our products, we will foster an environment of success and trust with physicians and patients.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify">We share the responsibility of maintaining
our high-quality standards by:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 72pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">Making patient safety a paramount focus of internal and contracted operations that support the
development of our products;</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 72pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">Following all applicable laws, regulations and Company policies and procedures;</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 72pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">Engaging only suppliers and other third parties who support the Company&#8217;s commitment to high
quality standards;</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 72pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">Never sacrificing quality to meet a deadline or target; and</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 72pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="font-family: Symbol">&#183;</FONT></TD><TD STYLE="text-align: justify">Raising any quality questions or concerns through appropriate channels.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt"></P>

<!-- Field: Page; Sequence: 9 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">B.</FONT></TD><TD STYLE="text-align: justify"><U>CLINICAL TRIALS</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0cm"><B>Putting Patients First</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0cm"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company is committed
to conducting all its clinical trial activities in accordance with International Council for Harmonization - Good Clinical Practice
(ICH - GCP), the international ethical and scientific quality standard for designing, conducting, recording and reporting medical
trials that involve the participation of human subjects. Compliance with this standard provides public assurance that the rights,
safety and well-being of trial subjects are protected, and that the clinical trial data is credible. We protect patient rights
through appropriate informed consent procedures, compliance with ICH &ndash; GCP and documentation of our compliance with all applicable
privacy-related policies and regulations.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">We only conduct or sponsor
trials under the direction of experienced investigators and in compliance with protocols that have received all necessary prior
approvals from institutional review boards (IRB), independent ethics committees (IEC) or other applicable authorized bodies or
agencies.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">As part of our commitment
to improve the overall quality of life for people living with neurodegenerative and neurodevelopmental disorders, we recognize
the importance of fully understanding the needs and rights of the vulnerable populations that participate in our clinical trials.
The following principals must guide our clinical research:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Participants must not be
exposed to unnecessary risks.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 45pt; text-align: justify; text-indent: -9pt">Participants and
their caregivers must understand the nature and purpose of the clinical research via informed consent procedures.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 45pt; text-align: justify; text-indent: -9pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Privacy and confidentiality
rules must be strictly adhered to.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 45pt; text-align: justify; text-indent: -9pt">Information gathered
must enable transparent and accurate reporting, interpretation and verification of study outcomes.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 45pt; text-align: justify; text-indent: -9pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">In working with patient
advocacy groups and organizations, always exercise respect and transparency, maintaining independence of these groups&rsquo; and
working cooperatively for the benefit of patients by being responsive to patient and physician requests and questions and respectful
of the physician-patient relationship. Employees are responsible for ensuring all product communications made with patient organizations
are factually accurate and consistent with legal and research requirements.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0cm"><B>Working with Vendors</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0cm"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">We work with various outside
vendors to perform certain research, development and commercial activities. These vendors must comply with all applicable international
and local healthcare program and regulatory requirements, including the FDA. Any employee who is responsible for such vendor&rsquo;s
activities must ensure that the vendor understands that, in performing services on behalf of the Company, they must adhere to the
same high standards to which Anavex is held. Employees who are concerned that a vendor is not conducting its activities in compliance
with Anavex&rsquo;s policies and procedures should report compliance concerns to the CEO.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Our vendor selection policy
is to select vendors based on the merits of their products, services and business practices and to purchase supplies based on need,
quality, service, price and other terms and conditions of sale. You may not establish a business relationship with a vendor if
you know or have reason to know that its business practices violate applicable laws or our Code of Conduct.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>Environmental Compliance</B></P>

<P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">It is our policy
to conduct our business in an environmentally responsible way that minimizes environmental impacts. We are committed to minimizing
and, if practicable, eliminating the use of any substance or material that may cause environmental damage, reducing waste generation
and disposing of all waste through safe and responsible methods, minimizing environmental risks by employing safe technologies
and operating procedures, and being prepared to respond appropriately to accidents and emergencies.</P>

<P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"></P>

<!-- Field: Page; Sequence: 10 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XXIII.</FONT></TD><TD STYLE="text-align: justify"><U>RETENTION OF BUSINESS RECORDS</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Records retention policies
seek to establish consistent practices concerning how long records should be kept and when, in the normal course of business, they
should be destroyed. All Covered Persons must comply at all times with all laws, rules and regulations relating to records preservation,
all records retention policies and all document or record preservation notices. Records must be maintained for the duration of
the assigned retention periods. A record includes any information, regardless of physical format, which has been created or received
in the transaction of the Company&rsquo;s business. Physical format of a record includes paper documents, CDs, DVDs, computer hard
disks, e-mail, floppy disks, microfiche, microfilm or all other media and data storage devices. The retention and proper disposal
of the Company Group&rsquo;s records shall be in accordance with established Company policies and applicable legal and regulatory
requirements.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">If the existence of any
pending or threatened legal action, subpoena or investigation is known or reported to you, promptly contact the CEO. You must retain
all records that may relate to any pending or threatened legal action, subpoena or investigation. If you have a question as to
whether a record pertains to a pending or threatened legal action, subpoena or investigation, contact the CEO before disposing
of the record in question.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XXIV.</FONT></TD><TD STYLE="text-align: justify"><U>ANTI-BRIBERY AND ANTI-CORRUPTION POLICY</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">This Anti-Bribery and Anti-Corruption
Policy of Anavex (the &ldquo;<B>Policy</B>&rdquo;) is designed to ensure compliance with the US Foreign Corrupt Practices Act of
1977 (the &ldquo;<B>FCPA</B>&rdquo;), as well as with the principles described in the Convention on Combating Bribery of Foreign
Public Officials in International Business Transactions and any local anti-bribery or anti-corruption laws existing where Anavex
and its affiliates operates (collectively, the &ldquo;<B>Anti-Corruption Laws</B>&rdquo;). This Policy applies to all Covered Persons.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Anavex takes a zero-tolerance
approach to bribery and corruption. All Company personnel are expected to conduct business legally and ethically, in accordance
with best practices. As a general principle, Anavex and its representatives shall not transfer or offer to transfer any type of
benefit for the purpose of influencing a public official to misuse his or her power or influence.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">A.</FONT></TD><TD STYLE="text-align: justify"><U>PURPOSE AND APPLICATION OF THIS POLICY</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The purpose of this Policy
is to establish the obligations of Anavex, and of those working on behalf of the Company, in observing and upholding its position
on bribery and corruption, and to provide guidance on how to recognize and deal with bribery and corruption issues. As the FCPA
has extraterritorial application, Anavex, along with all Covered Persons will be bound by these laws in relation to conduct in
all countries in which they operate. This Policy is not intended to supplant the Anti-Corruption Laws.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">B.</FONT></TD><TD STYLE="text-align: justify"><U>COMPLIANCE REQUIREMENTS</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><U>Prohibited Activities</U>
&ndash; No Covered Person shall, directly or indirectly give, offer or agree to give anything of value of any kind (including any
payment, loan, gift, reward, advantage, benefit or service) to a public official or to any person for the benefit of a public official:
(a) as consideration for an act or omission by the official in connection with the performance of his/her duties; or (b) to induce
the official to use his/her position to influence any acts or decisions of the government for which the official performs his/her
duties.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">A &ldquo;<B>public official</B>&rdquo;
includes any person who holds a legislative, administrative or judicial position of a state; a person who performs public duties
or functions for a state, including a person employed by a board, commission, corporation state-owned company or other body or
authority that is established to perform a duty or function on behalf of a state, or is performing such a duty or function; and
an official or agent of a public international organization that is formed by two or more states or governments, or by two or more
such public international organizations. A &ldquo;state&rdquo; means any country, and includes any political subdivision of that
country (such as a province or territory); the government, and any department, or branch of that country or of a political subdivision
of that country; or any agency of that country or of a political sub-division of that country.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"></P>

<!-- Field: Page; Sequence: 11 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Bribes given through an
agent or received by a party other than a public official are also prohibited if the ultimate goal is to influence a public official
by conferring a benefit. Any question about whether someone is a public official should be directed to the CEO.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Covered Persons may not
make or authorize cash or cash equivalent (e.g. check) reimbursements or payments of any kind to individual public officials without
prior written authorization from the CEO.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><B><I><U>No Facilitation
Payments</U></I></B> &ndash; Anavex does not make &ldquo;facilitation payments&rdquo; or &ldquo;kickbacks&rdquo; of any kind, regardless
of whether such payments are permitted under applicable law. Facilitation payments are typically small, unofficial payments made
to secure or expedite a routine government action by a government official (such as the issuance of permits, licenses, provision
of mail pick-up and delivery etc.). Kickbacks are typically payments made in return for a business favor or advantage and can include
discounts or other types of cash incentives.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">All Covered Persons must
avoid any activity that might lead to, or suggest, that a facilitation payment or kickback will be made by, on behalf of, or otherwise
in connection with the business of or for the benefit of the Company.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">If asked to make a payment
on the Company&rsquo;s behalf, always be mindful of what the payment is for and whether the amount requested is proportionate to
the goods or services provided. Always obtain a receipt which details the reason for the payment and evidences that the payment
went directly to the appropriate payee who provided the goods or services. Any suspicions, concerns or questions regarding a payment
should be raised with the CEO.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><B><I><U>Lodging and Travel
Expenses</U></I></B> &ndash; If any Covered Person proposes to reimburse the bona fide and reasonable travel and lodging expenses
of a public official, such Covered Person shall document such proposed reimbursement, lodging or services and shall consult with
the CEO to determine the propriety of any such proposed reimbursement and obtain the CEO&rsquo;s prior written authorization before
making any offer to such Public Official. In any such case, the amount and purpose of such reimbursement, lodging or services must
be reasonable and must relate directly to either: (a) the promotion, demonstration, or explanation of the Company&rsquo;s services
or operations with a government, government agency, or government-owned or government-controlled enterprise or the performance
of an official duty related to the Company; or (b) the execution or performance of a contract with a state or related organization.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><B><I><U>Gifts and Hospitality</U></I></B>
&ndash; This Policy does not prohibit normal, appropriate and modest hospitality to or from third parties. These customary courtesies
are designed to build goodwill among business partners.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The test to be applied is
whether in all the circumstances the gift or hospitality is reasonable and justifiable (both from the perspective of the provider
and recipient) rather than lavish and extraordinary; bearing in mind that what may normally be viewed as small or insignificant
in some countries can be of significant value in another. The intention behind the gift should always be considered and nothing
should be explicitly or implicitly expected or demanded in return.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The giving of gifts and
corporate hospitality or entertainment is not prohibited, if the following requirements are met:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 72pt"></TD><TD STYLE="width: 36pt">(a)</TD><TD STYLE="text-align: justify">it is done in the normal course of the Company&rsquo;s business and without the intention of, or
without a reasonable prospect of, influencing a public official to obtain or retain an improper business advantage, or to reward
the provision or retention of an improper business advantage, or in explicit or implicit exchange for favors or benefits;</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 72pt"></TD><TD STYLE="width: 36pt">(b)</TD><TD STYLE="text-align: justify">it complies with applicable local law;</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 72pt"></TD><TD STYLE="width: 36pt">(c)</TD><TD STYLE="text-align: justify">it does not include cash or a cash equivalent;</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 72pt"></TD><TD STYLE="width: 36pt">(d)</TD><TD STYLE="text-align: justify">it must be properly recorded and disclosed, and not paid personally to avoid any approval or disclosure
requirements;</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 72pt"></TD><TD STYLE="width: 36pt">(e)</TD><TD STYLE="text-align: justify">taking into account the reason for the gift or hospitality, it is of an appropriate type and value
in the applicable country/region and given at an appropriate time;</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt"></P>

<!-- Field: Page; Sequence: 12 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 72pt"></TD><TD STYLE="width: 36pt">(f)</TD><TD STYLE="text-align: justify">it is given openly and in the Company&rsquo;s name, not secretly; and</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 72pt"></TD><TD STYLE="width: 36pt">(g)</TD><TD STYLE="text-align: justify">it is not given or received frequently between the same individuals.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 108pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Gifts or hospitality should
not be offered to Public Officials or government representatives, or politicians or political parties, without the prior approval
of the CEO.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><B><I><U>Community Funding</U></I></B>
&ndash; Government officials or their representatives may request or expect funding for consideration or approval of regulatory
matters involving the Company. The Company may be given opportunities to financially support development initiatives of communities
in proximity to its projects or make charitable contributions. Although it may be customary to do so, no Covered Person may make
or commit to such funding, contributions or payments to public officials on behalf of the Company without the prior written approval
of the Company&rsquo;s CEO. In each of these scenarios, such payments or contributions may be prohibited under applicable laws
and, accordingly, in order to avoid involvement in improper conduct, it is critically important that the Company be diligent in
confirming details of the nature of the payment in question, including with respect to who the intended beneficiaries of the contribution
in question are, and how they will benefit.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><B><I><U>Political Contributions</U></I></B>
&ndash; No Covered Persons should make any contribution or provide any financial support to any political party or candidate on
behalf of Anavex, except as may be pre-approved by the Company&rsquo;s CEO. No Political Contributions may be used as a subterfuge
for bribery.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">In undertaking any political
activity that is not authorized by this policy or other policies of the Company, all Covered Persons will be deemed to be acting
in their personal capacity or that of their own corporate organization and not on behalf of the Anavex.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><B><I><U>Record Keeping</U></I></B>
&ndash; All accounts, invoices, memoranda and other documents and records relating to dealings with third parties must be prepared
and maintained with strict accuracy and completeness. Covered Persons must ensure that all expense reports relating to hospitality,
gifts or expenses incurred to third parties are submitted in accordance with the relevant Company policies and that the reasons
for the expenditures are specifically recorded. No accounts or transactions must be kept &ldquo;off-book&rdquo; for any reason,
including to facilitate or conceal improper payments. Recording of any payments in any way which would conceal their true nature
constitutes a violation of this Policy and applicable laws.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">All document processing
payments, attachments to justify payment requests, classification of payments, authorizations, and certifications subject to this
Policy must be capable of being retrieved at least for five (5) years.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">C.</FONT></TD><TD STYLE="text-align: justify"><U>PENALTIES FOR NON-COMPLIANCE</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Individuals who fail to
comply with this Policy may face severe consequences which could include internal disciplinary action or termination of employment
or service arrangements without advance notice. If it appears that any Covered Person may have violated any applicable Anti-Corruption
Laws, then the Company may refer the matter to the appropriate regulatory authorities, which could lead to penalties, fines or
imprisonment for Anavex and/or the responsible person.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company may be held
liable where any of its employees, agents, contractors or other representatives has engaged in bribes or other forms of corruption
or misconduct, whether known or not by senior management. Companies charged under the Anti-Corruption Laws may be subject to significant
fines, negative effects on its share price and material damage to its reputation. A convicted company may also be ordered to forfeit
all proceeds obtained from an act of bribery.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">D.</FONT></TD><TD STYLE="text-align: justify"><U>POLICY IMPLEMENTATION AND OVERSIGHT</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company&rsquo;s Board
has overall responsibility for ensuring this Policy complies with the Company&rsquo;s legal and ethical obligations, and that all
those under the Company&rsquo;s control comply with it.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company&rsquo;s CEO
has primary responsibility for overseeing the implementation of this Policy, and for monitoring its suitability, adequacy and effectiveness.
Where appropriate the CEO may consult with other officers of the Company prior to making determinations in relation to this Policy.
Management at all levels is responsible for ensuring that those reporting to them are made aware of, understand and comply this
Policy.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"></P>

<!-- Field: Page; Sequence: 13 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company shall continue
to develop, implement, monitor and maintain a system of internal controls to facilitate and assess compliance with this Policy
by its employees, agents, contractors and consultants.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">These systems shall include
the following elements:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 54pt"><FONT STYLE="font-family: Symbol">-&#9;</FONT>All
officers and directors, all corporate employees, all members of the executive committee and certain additional employees in positions
that require them to interact with public officials, approve payments or keep accounting records (the &#8220;<B>Designated Employees</B>&#8221;),
will receive relevant training on how to implement and adhere to this Policy. All Designated Employees will provide annual certification
of compliance with this Policy.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 54pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 54pt"><FONT STYLE="font-family: Symbol">-&#9;</FONT>Internal
audits will be conducted periodically to assess whether this Policy is effective in (i) increasing awareness among Covered Persons
of bribery and corruption issues, and the significance thereof; (ii) systematically reducing the risk of occurrence of bribery
and corruption related incidents involving the Company; (iii) establishing appropriate written records to evidence that reasonable
care and diligence have been taken to ensure compliance in these areas.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 54pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 54pt"><FONT STYLE="font-family: Symbol">-&#9;</FONT>Internal
audits will be conducted periodically in order to monitor instances of non-compliance by Covered Persons, with appropriate follow-up
action as warranted.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 54pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 54pt"><FONT STYLE="font-family: Symbol">-&#9;</FONT>A
report will be provided to the Board on an annual basis confirming that: (a) all annual certifications have been obtained, and
summarizing the results thereof; (b) an internal audit of the effectiveness of this Policy has been duly completed; and (c) material
issues that are identified are reported to the Board and appropriate corrective action is taken.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 54pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 54pt"><FONT STYLE="font-family: Symbol">-&#9;</FONT>The
Company shall conduct an anti-bribery risk review of projects or proposals involving business in new jurisdictions. The level of
due diligence conducted should be consistent with the level of risk to be managed, and must include an assessment of the prevalence
of bribery, corruption and other unacceptable behavior in such new market.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 54pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 54pt"><FONT STYLE="font-family: Symbol">-&#9;</FONT>Due
diligence on potential acquisition targets must include consideration of whether the target and its representatives have complied
with applicable bribery and corruption legislation. Employment, consultancy, agency and similar agreements entered into by the
Company, where the employees will be Designated Employees or consultants or agents are expected to have interaction with public
officials, shall require counterparties to acknowledge and agree that they understand, and shall comply with, this Policy.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 54pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">E.</FONT></TD><TD STYLE="text-align: justify"><U>COMMUNICATION OF THIS POLICY</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">This Policy, along with
any updates hereto, will be posted on the Company&rsquo;s website. A copy of the Policy will be provided to all Designated Employees
and to all agents, consultants and contractors of Anavex having interaction with public officials on behalf of Anavex, and they
will be advised that the Policy is available on the Anavex website for their review, and informed whenever significant changes
are made.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Education on this Policy
will form part of the orientation or induction process for all new Designated Employees. In addition, this Policy shall be communicated
to any agent, contractor or consultant having interaction with public officials on behalf of Anavex at the outset of the business
relationship, and as appropriate thereafter. For advice on these communications, please contact the Company&rsquo;s CEO.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">F.</FONT></TD><TD STYLE="text-align: justify"><U>REPORTING OBLIGATIONS</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: 36pt">1.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&#9;<U>Reporting</U>.
All Covered Persons must immediately report any known, suspected or suggested violations of this Policy to the Company&rsquo;s
CEO. Alternatively, Covered Persons can report any known, suspected or suggested violations of this Policy through the Company&rsquo;s
Whistleblower Hotline by one of the following methods:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: 36pt"></P>

<!-- Field: Page; Sequence: 14 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: 36pt">a.&#9;<B>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<I>Email</I></B>.
By email on a confidential basis which is forwarded directly to a designated member of the Board of Directors (the &ldquo;<B>Board
Member</B>&rdquo;) to: anavexhotline@anavexcorp.com. This hotline email address is forwarded directly to the Board Member who will
maintain anonymity if so requested. However, employees may also use a non-identifiable or third party email address to submit anonymous
complaints to the hotline.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: 36pt">b.&#9;<B><I>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Audio
Message</I></B>. Employees or others wishing to lodge a complaint or raise compliance concerns may contact 917-460-0668 to record
an audio message. An audio file will be created and will be forwarded to the Board Member.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Additionally, Covered Persons may contact the
Company&rsquo;s CEO with a question or concern about the application of this Policy. Any questions or violation reports will be
addressed immediately and taken seriously, and can be made anonymously. The CEO, Board Member or his/her designee will investigate
any reported violations, and, if warranted, will determine an appropriate response, including corrective action and preventative
measures. All reports will be treated confidentially to every extent possible.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Company will maintain a record of all reports
under this Policy, tracking their receipt, investigation and resolution.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Company will promptly report any violations
of applicable law to appropriate regulatory authorities.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: 36pt">2.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&#9;<U>Protection</U>.
The Company encourages openness and will support anyone who raises genuine concerns in good faith under this policy, even if they
turn out to be mistaken.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Company is committed to ensuring no one
suffers any detrimental treatment as a result of refusing to take part in bribery or corruption, or because of reporting in good
faith their suspicion that an actual or potential bribery or other corruption offence has taken place, or may take place in the
future. Detrimental treatment includes dismissal, disciplinary action, threats or other unfavorable treatment connected with raising
a concern. If you believe that you have suffered any such treatment, you should inform the Company&rsquo;s CEO immediately. If
the matter is not remedied, and you are an employee, you should raise it formally with the CEO.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">G.</FONT></TD><TD STYLE="text-align: justify"><U>CONCLUSIONS</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The prevention, detection
and reporting of bribery offences and other forms of corruption are the responsibility of all those working for Anavex or on its
behalf. If you have any questions about this Policy, please do not hesitate to contact the Company&rsquo;s CEO.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XXV.</FONT></TD><TD STYLE="text-align: justify"><U>POLITICAL CONTRIBUTIONS</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company Group&rsquo;s
funds or assets may not be contributed, directly or indirectly, to any political party, committee or candidate, or the holder of
any federal, state or local government office within the United States unless prior approval has been given by the Company&rsquo;s
CEO. In countries other than the United States in which political contributions by companies are lawful, a political contribution
may be made only upon the prior specific written approval of the Company&rsquo;s CEO. Covered Persons shall not be directed, pressured
or coerced in any manner by a director, officer or any individual acting in a managerial or supervisory capacity to make a contribution
to any political party or committee or to any candidate for or the holder of any government office.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XXVI.</FONT></TD><TD STYLE="text-align: justify"><U>WORKPLACE COMPLIANCE</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">It is the Company&rsquo;s
policy to attract and retain ethically committed and competent employees and to provide them with the education, training and growth
opportunities that encourage professional development. The Company believes that it is important to establish key result areas
for individual performance and provide transparent and uniform assessment feedback that encourages continuous improvement. The
Company&rsquo;s policies help foster an environment for employee development and investment into their success.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"></P>

<!-- Field: Page; Sequence: 15 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">A.</FONT></TD><TD STYLE="text-align: justify"><U>Equality and Harassment</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company is an equal
opportunity employer. The Company values a diverse workforce and proudly reflects a Company culture developed with a variety of
ethnic backgrounds, nationalities, races, ages, genders, political affiliates, sexual preferences, and religions. The Company is
committed to fostering a work environment in which all individuals are treated with respect and dignity and is committed to promoting
and maintaining an inclusive, high- performing culture. All team members embrace and leverage each other&rsquo;s talents and backgrounds
and nourish innovative thinking to achieve their full potential and contribute to our shared success.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company does not unlawfully
discriminate, nor does it allow its employees to unlawfully discriminate. The Company expects that all relationships among persons
in the workplace will be business-like and free of unlawful discrimination, bias, prejudice and harassment. Prohibited harassment
includes conduct that is intended to or that has the effect of unreasonably interfering with a fellow employee&rsquo;s work performance
or creating an environment that is intimidating, hostile, or offensive to the employee. Any hostile or demeaning behavior based
upon an employee&rsquo;s race, religion, national origin, age, gender, disability, sexual preference, political affiliation, marital
status or veteran status will be construed as a violation of this policy and will be dealt with as such.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">B.</FONT></TD><TD STYLE="text-align: justify"><U>Workplace Safety and Health</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company conducts its
operations with the highest regard for the safety and health of all employees and is committed to maintaining a safe and healthy
workplace. The Company will endeavor to provide a safe and healthy workplace and to ensure that its operations do not cause any
adverse impact or injury to the environment or to the communities in and around its workspaces. Employees must comply with all
established safety rules and procedures, as well as all applicable federal, state and local health and safety laws including those
issued by the Occupational Safety and Health Administration. When an unsafe condition or practice is identified, appropriate action
must be taken promptly to correct the condition and to prevent it from happening again. Employees must report any violation of
a safety rule, procedure or law of which they are aware or any accident, workplace injury, or any situation presenting a danger
of injury.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">C.</FONT></TD><TD STYLE="text-align: justify"><U>Substance Abuse</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">It is our policy to maintain
a drug-free work environment. Use of illegal drugs, alcohol abuse and the misuse of legal drugs create serious health and safety
risks in the workplace. The sale, transfer, or possession of illegal drugs or being under the influence of such drugs is strictly
prohibited. Reporting to work or any Company business function under the influence of and/or impairment by any such substance or
alcohol is also strictly prohibited. It is important that cases of drug or alcohol abuse be brought to the CEO&rsquo;s attention
immediately.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">D.</FONT></TD><TD STYLE="text-align: justify"><U>Workplace Violence</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company is committed
to a safe working environment, free of threats, malicious behavior, intimidation and physical harm. All employees have a right
to work in a safe environment and share the responsibility for assuring each other&rsquo;s safety. The Company prohibits violence-related
conduct including, but not limited to, physical assaults, fighting, threatening comments, intimidation and the intentional destruction
of any company property, employee property, or merchandise. Any comments or behavior that could be reasonably interpreted as intent
to do harm to employees, their family or their property will be considered a threat. Any employee who believes that he or she may
be the target of violence or threats of violence, or is aware of violent or threatening conduct by another individual, that could
result in injury to any employee or the destruction of property, has a responsibility to immediately report the situation to the
CEO.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">E.</FONT></TD><TD STYLE="text-align: justify"><U>No Retaliation</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company adheres to an
&ldquo;Open Door Policy,&rdquo; and encourages Company personnel to discuss with their manager or the CEO any compliance issues,
concerns, problems and/or suggestions without fear of retaliation and with the assurance that the matter will be kept as confidential
as possible.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company follows a strict
non-retaliation policy as part of its Code of Business Conduct. As a result, retaliation against any individual who reports discrimination,
harassment or violence or participates in an investigation of such reports is prohibited. Retaliation against an individual for
reporting discrimination, harassment or violence or for participating in an investigation of a claim of harassment or discrimination
is a serious violation of this Code and Company policies.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"></P>

<!-- Field: Page; Sequence: 16 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">F.</FONT></TD><TD STYLE="text-align: justify"><U>At-Will Employment</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">Unless otherwise agreed
in writing by the CEO, each Company employee is employed on an at-will basis. This means that there is no guarantee of continued
employment and the Company has the right to terminate an individual&rsquo;s employment at any time with or without cause. Oral
representations cannot alter this relationship. Therefore, this Code of Conduct will not be construed or interpreted as creating
an implied contract with any employee that he or she may be discharged only for cause. Employment with the Company is voluntarily
entered into, and the employee is free to resign at will at any time, for any or no reason, with or without notice. Similarly,
the Company may terminate the employment relationship at will at any time, for any or no reason, with or without notice, so long
as there is no violation of applicable federal, state or local law.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 36pt"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">G.</FONT></TD><TD STYLE="text-align: justify"><U>Background Checks and Disclosure of Suspension/Debarment/Felony/Other Criminal Conviction</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 72pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Company has determined
that for all positions within the Company, a criminal history records check is required for candidates, when information as to
a candidate&rsquo;s criminal history is job-related to the position being sought. The determination has been made on the basis
of the particular requirements of the job, the employer&rsquo;s business necessity, and applicable federal and state laws. In addition,
candidates may be required to submit to a post-offer drug screen. The Company is an equal opportunity employer and does not discriminate
on the basis of race, sex, age, national origin, religion, disability, genetic information, or any other characteristic protected
by federal, state or local laws.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">In addition, the Company
requires the ongoing disclosure of all criminal convictions (including, among others, any conviction where an appeal is pending,
any plea of guilty or nolo contendere, and any participation in a first offender, deferred adjudication, or other similar arrangement
or program where judgment of conviction has been withheld), and may terminate the employment of any employee as a result, in the
discretion of management. To comply with these requirements, you must inform the CEO if you are convicted of a felony or misdemeanor
crime.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XXVII.</FONT></TD><TD STYLE="text-align: justify"><U>WAIVERS OF OR CHANGES TO THE CODE OF BUSINESS CONDUCT AND ETHICS</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">It may be appropriate for
a provision of this Code to be waived in a particular circumstance. Any waiver of, or changes to, this Code that apply to executive
officers or directors of the Company may be made only by the Nominating Committee or another committee of our Board comprised solely
of independent non-executive directors or a majority of our independent non-executive directors and must be promptly disclosed
to shareholders as required by law or regulation of the SEC and the rules of the Nasdaq. In particular, to the extent that such
committee determines to grant any waiver of this Code for an executive officer or director, the waiver shall be disclosed to shareholders
within four business days of such determination through a press release, providing website disclosure, or by filing a current report
on Form 8-K with the SEC. Any other Covered Person seeking a waiver should speak to his or her supervisor, who, in turn, should
obtain the written approval of the CEO regarding such matter.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">For the avoidance of doubt,
no waiver shall be given from any provision of this Code that is not permitted under applicable law, rules or regulations.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XXVIII.</FONT></TD><TD STYLE="text-align: justify"><U>COMPLIANCE</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The matters covered in this
Code are of the utmost importance to the Company, the Company Group as a whole, and their respective stakeholders and business
partners, and are essential to the Company Group&rsquo;s ability to conduct its business in accordance with its stated values.
The Company expects all Covered Persons and persons with whom the Company Group transacts business to adhere to the standards set
forth in this Code in carrying out their duties to the Company Group. Individuals whose actions are deemed to be in violation of
this Code or other policies of the Company that may be adopted from time to time will be subject to disciplinary action, up to
and including suspension, termination and/or the reporting of violative conduct to the appropriate authorities and potential civil
liability and criminal prosecution.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XXIX.</FONT></TD><TD STYLE="text-align: justify"><U>ADMINISTRATION AND IMPLEMENTATION</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">The Board has overall responsibility
for administering and interpreting this Code. The CEO is responsible for the implementation of this Code.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 36pt"><FONT STYLE="text-underline-style: none">XXX.</FONT></TD><TD STYLE="text-align: justify"><U>WEBSITE DISCLOSURE</U></TD></TR></TABLE>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0 0 0 36pt; text-align: justify; text-indent: -36pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">This Code, as may be amended
from time to time, shall be posted on the Company&rsquo;s website. The Company shall state in its annual proxy statement that this
Code is available on the Company&rsquo;s website and provide the website address.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt">&nbsp;</P>

<P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><B>Approved: August 1, 2023</B></P>

<P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><B></B></P>

<!-- Field: Rule-Page --><DIV ALIGN="LEFT" STYLE="margin-top: 3pt; margin-bottom: 3pt"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; width: 100%">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt/normal Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-21.1
<SEQUENCE>3
<FILENAME>e5240_ex21-1.htm
<DESCRIPTION>EXHIBIT 21.1
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 12pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: right">Exhibit 21.1</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: right">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>SUBSIDIARIES OF THE REGISTRANT</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="width: 48%; border-bottom: black 1pt solid"><FONT STYLE="font-size: 10pt"><B>Name of Subsidiary</B></FONT></TD>
    <TD STYLE="width: 4%">&nbsp;</TD>
    <TD STYLE="width: 48%; border-bottom: black 1pt solid"><FONT STYLE="font-size: 10pt"><B>Jurisdiction of Incorporation or Organization</B></FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-size: 10pt">Anavex Australia Pty Limited</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-size: 10pt">Australia</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-size: 10pt">Anavex Germany GmbH</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-size: 10pt">Germany</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-size: 10pt">Anavex Canada Ltd.</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-size: 10pt">Ontario, Canada</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 3pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>4
<FILENAME>e5240_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 12pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0; text-align: right">EXHIBIT 23.1</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING
FIRM</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We have issued our reports dated November 27, 2023,
with respect to the consolidated financial statements and internal control over financial reporting included in the Annual Report of Anavex
Life Sciences Corp. on Form 10-K for the year ended September 30, 2023. We consent to the incorporation by reference of said reports in
the Registration Statements of Anavex Life Sciences Corp. on Forms S-3 (No. 333-218292, and No. 333-259788) and Forms S-8 (No. 333-219934,
No. 333-255166 and No. 333-265537).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">/s/ GRANT THORNTON LLP</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: left">Melville, New York<BR>
November 27, 2023</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: left">&nbsp;<FONT STYLE="color: Black">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 45pt; text-align: justify; color: fuchsia"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 3pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 45pt; text-align: justify; color: fuchsia">&nbsp;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>5
<FILENAME>e5240_ex23-2.htm
<DESCRIPTION>EXHIBIT 23.2
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 12pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: right; color: fuchsia"><FONT STYLE="color: Black"><B><U STYLE="text-decoration: none">EXHIBIT
23.2</U></B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center; color: fuchsia"><FONT STYLE="color: Black"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center; color: fuchsia"><FONT STYLE="color: Black"><U>Consent
of Independent Registered Public Accounting Firm</U></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><FONT STYLE="color: Black">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><FONT STYLE="color: Black">Anavex
Life Sciences Corp.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><FONT STYLE="color: Black">New York,
New York</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><FONT STYLE="color: Black">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><FONT STYLE="color: Black">We hereby
consent to the incorporation by reference in the Registration Statements on Form S-3 (No. 333-218292 and No. 333-259788) and Form S-8
(No. 333-219934, No. 333-255166 and No. 333-265537) of Anavex Life Sciences Corp. and subsidiaries of our report dated November 24, 2021,
relating to the consolidated financial statements of Anavex Life Sciences Corp. and subsidiaries, which appears in this Annual Report
on Form 10-K.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="color: Black">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="color: Black"><U STYLE="text-decoration: none">/s/ BDO USA, P.C.</U></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="color: Black">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><FONT STYLE="color: Black">New York,
New York</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: fuchsia"><FONT STYLE="color: Black">November
27, 2023</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 45pt; text-align: justify; color: fuchsia"><FONT STYLE="color: Black">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 45pt; text-align: justify; color: fuchsia"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 3pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 45pt; text-align: justify; color: fuchsia">&nbsp;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-31.1
<SEQUENCE>6
<FILENAME>e5240_ex31-1.htm
<DESCRIPTION>EXHIBIT 31.1
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 12pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="margin: 0"><P STYLE="text-align: right; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>EXHIBIT
31.1</B></FONT></P>

<P STYLE="margin: 0; text-align: right">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>CERTIFICATION</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">I, Christopher Missling, certify that:</P>

<P STYLE="font: 11pt/115% Calibri, Helvetica, Sans-Serif; margin: 0pt">&nbsp;&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">1.</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">I have reviewed
this Annual Report on Form 10-K of Anavex Life Sciences Corp.;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Based on my knowledge,
this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements
made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this
report;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Based on my knowledge,
the financial statements, and other financial information included in this report, fairly present in all material respects the financial
condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">The registrant&rsquo;s
other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in
Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f)
and 15d-15(f)) for the registrant and have:</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; width: 2%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom; width: 1%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; vertical-align: top; width: 2%; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">a)</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top; width: 95%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Designed such disclosure
controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material
information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities,
particularly during the period in which this report is being prepared;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; vertical-align: top; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; vertical-align: top; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">b)</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Designed such internal control
over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable
assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance
with generally accepted accounting principles;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; vertical-align: top; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; vertical-align: top; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">c)</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Evaluated the effectiveness
of the registrant&rsquo;s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of
the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; vertical-align: top; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; vertical-align: top; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">d)</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Disclosed in this report any
change in the registrant&rsquo;s internal control over financial reporting that occurred during the registrant&rsquo;s most recent fiscal
quarter (the registrant&rsquo;s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably
likely to materially affect, the registrant&rsquo;s internal control over financial reporting; and</FONT></TD></TR>
</TABLE>

<P STYLE="font: 11pt/115% Calibri, Helvetica, Sans-Serif; margin: 0pt">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
  <TR>
    <TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif; width: 2%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.</FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 1%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="text-align: justify; vertical-align: top; width: 97%"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
                                    registrant&rsquo;s other certifying officer(s) and I have disclosed, based on our most recent evaluation
                                    of internal control over financial reporting, to the registrant&rsquo;s auditors and the audit committee
                                    of the registrant&rsquo;s board of directors (or persons performing the equivalent functions):</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></P></TD></TR>
  </TABLE>
<P STYLE="margin: 0pt; font: 11pt/115% Calibri, Helvetica, Sans-Serif">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR>
<TD STYLE="vertical-align: top; width: 2%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom; width: 1%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif; text-align: justify; width: 2%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">a)</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top; width: 95%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">All significant deficiencies
and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely
affect the registrant&rsquo;s ability to record, process, summarize and report financial information; and</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">b)</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Any fraud, whether or not material,
that involves management or other employees who have a significant role in the registrant&rsquo;s internal control over financial reporting.</FONT></TD></TR>
</TABLE>

<P STYLE="font: 11pt/115% Calibri, Helvetica, Sans-Serif; margin: 0pt">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="width: 50%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Date: November 27, 2023 </FONT></TD>
<TD STYLE="width: 50%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>/s/ Christopher Missling</I></FONT></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: Black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Christopher
Missling, PhD </FONT></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chief
Executive Officer, President, Secretary<BR> (Principal Executive Officer)</FONT></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
</TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 3pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-31.2
<SEQUENCE>7
<FILENAME>e5240_ex31-2.htm
<DESCRIPTION>EXHIBIT 31.2
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0">&nbsp;</P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 12pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0"></P>

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="margin: 0; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>EXHIBIT 31.2</B></FONT></P>

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>CERTIFICATION</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">I,
Sandra Boenisch, certify that:</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;&nbsp;&nbsp;</FONT></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">1.</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">I have reviewed
this Annual Report on Form 10-K of Anavex Life Sciences Corp.; &nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif">&nbsp;</TD>
<TD STYLE="vertical-align: bottom">&nbsp;</TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top">&nbsp;</TD></TR>
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Based on my knowledge,
this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements
made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this
report; &nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif">&nbsp;</TD>
<TD STYLE="vertical-align: bottom">&nbsp;</TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top">&nbsp;</TD></TR>
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Based on my knowledge,
the financial statements, and other financial information included in this report, fairly present in all material respects the financial
condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report; &nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif">&nbsp;</TD>
<TD STYLE="vertical-align: bottom">&nbsp;</TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top">&nbsp;</TD></TR>
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">The registrant&rsquo;s
other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in
Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f)
and 15d-15(f)) for the registrant and have: &nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif">&nbsp;</TD>
<TD STYLE="vertical-align: bottom">&nbsp;</TD>
<TD COLSPAN="2" STYLE="text-align: justify; vertical-align: top">&nbsp;</TD></TR>
<TR>
<TD STYLE="vertical-align: top; width: 2%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom; width: 1%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; vertical-align: top; width: 2%; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">a)</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top; width: 95%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Designed such disclosure
controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material
information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities,
particularly during the period in which this report is being prepared; &nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; vertical-align: top; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; vertical-align: top; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">b)</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Designed such internal control
over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable
assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance
with generally accepted accounting principles; &nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; vertical-align: top; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; vertical-align: top; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">c)</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Evaluated the effectiveness
of the registrant&rsquo;s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of
the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and &nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; vertical-align: top; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; vertical-align: top; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">d)</FONT></TD>
<TD STYLE="text-align: justify; vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Disclosed in this report any
change in the registrant&rsquo;s internal control over financial reporting that occurred during the registrant&rsquo;s most recent fiscal
quarter (the registrant&rsquo;s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably
likely to materially affect, the registrant&rsquo;s internal control over financial reporting; and &nbsp;</FONT></TD></TR>
</TABLE>

<P STYLE="font: 11pt/115% Calibri, Helvetica, Sans-Serif; margin: 0pt">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
  <TR>
    <TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif; width: 2%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.</FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif; text-align: justify; width: 97%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">The registrant&rsquo;s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant&rsquo;s auditors and the audit committee of the registrant&rsquo;s board of directors (or persons performing the equivalent functions):</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 11pt/115% Calibri, Helvetica, Sans-Serif; margin: 0pt">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
  <TR>
    <TD STYLE="vertical-align: top; width: 2%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 1%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif; text-align: justify; width: 2%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">a)</FONT></TD>
    <TD STYLE="vertical-align: top; width: 95%"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">All
                                            significant deficiencies and material weaknesses in the design or operation of internal control
                                            over financial reporting which are reasonably likely to adversely affect the registrant&rsquo;s
                                            ability to record, process, summarize and report financial information; and</FONT></P></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="vertical-align: top; font: 11pt Calibri, Helvetica, Sans-Serif; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">b)</FONT></TD>
    <TD STYLE="vertical-align: top"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Any
                                    fraud, whether or not material, that involves management or other employees who have a significant
                                    role in the registrant&rsquo;s internal control over financial reporting.</FONT></P></TD></TR>
  </TABLE>
<P STYLE="font: 11pt/115% Calibri, Helvetica, Sans-Serif; margin: 0pt">&nbsp;&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="width: 50%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Date: November 27, 2023<I>&nbsp;</I></FONT></TD>
<TD STYLE="width: 50%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>/s/ Sandra Boenisch</I></FONT></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: Black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Sandra
Boenisch, CPA, CGA</FONT></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Principal
Financial Officer, Treasurer<BR> (Principal Financial and Accounting Officer)</FONT></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
</TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;&nbsp;</FONT></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 3pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0">&nbsp;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-32.1
<SEQUENCE>8
<FILENAME>e5240_ex32-1.htm
<DESCRIPTION>EXHIBIT 32.1
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 12pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="text-align: right; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>EXHIBIT 32.1</B></FONT></P>

<P STYLE="margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>CERTIFICATION
PURSUANT TO</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>18
U.S.C. SECTION 1350</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>AS
ADOPTED PURSUANT TO</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>SECTION
906 OF THE SARBANES-OXLEY ACT OF 2002</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">In
connection with the Annual Report of Anavex Life Sciences Corp. (the &ldquo;Company&rdquo;) on Form 10-K for the fiscal year ending September
30, 2023 as filed with the Securities and Exchange Commission on the date hereof (the &ldquo;Report&rdquo;), each of the undersigned,
in the capacities and on the date indicated below, hereby certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section
906 of the Sarbanes-Oxley Act of 2002, that to the best of his or her knowledge:</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%">
<TR STYLE="vertical-align: top">
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; width: 2%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD>
<TD STYLE="text-align: justify; width: 98%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">The Report fully complies with the requirements
of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and &nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(2)</FONT></TD>
<TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">The information contained in the Report fairly presents,
in all material respects, the financial condition and results of operations of the Company.</FONT></TD></TR>
</TABLE>

<P STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="padding: 0pt; width: 50%; text-indent: 0pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Date: November 27, 2023
&nbsp;</FONT></TD>
<TD STYLE="width: 50%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: Black 1pt solid; padding: 0pt 0pt 0pt 10pt; font: 11pt Calibri, Helvetica, Sans-Serif; text-indent: -10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>/s/
Christopher Missling</I></FONT></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding: 0pt 0pt 0pt 10pt; font: 11pt Calibri, Helvetica, Sans-Serif; text-indent: -10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Christopher
Missling, PhD</FONT></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="margin-top: 0; margin-bottom: 0"><P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chief Executive Officer, President, Secretary</FONT></P>
                                            <P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Principal Executive Officer) &nbsp;</FONT></P></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp; &nbsp; &nbsp;</FONT></TD></TR>
</TABLE>


<P STYLE="margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="border-bottom: Black 1pt solid; padding: 0pt 0pt 0pt 10pt; text-indent: -10pt; width: 50%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>/s/
Sandra Boenisch</I></FONT></TD>
<TD STYLE="width: 50%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="padding: 0pt 0pt 0pt 10pt; font: 11pt Calibri, Helvetica, Sans-Serif; text-indent: -10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Sandra
Boenisch, CPA, CGA</FONT></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; padding: 0pt; text-indent: 0pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Principal
Financial Officer, Treasurer (Principal Financial and Accounting Officer)</FONT></TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
</TABLE>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
foregoing certification is being furnished solely to accompany the Report pursuant to 18 U.S.C. &sect; 1350, and is not being filed for
purposes of Section 18 of the Securities Exchange Act of 1934, as amended, and is not to be incorporated by reference into any filing
of the Company, whether made before or after the date hereof, regardless of any general incorporation language in such filing. A signed
original of this written statement required by Section 906, or other document authenticating, acknowledging, or otherwise adopting the
signature that appears in typed form within the electronic version of this written statement required by Section 906, has been provided
to the Company and will be retained by the Company and furnished to the Securities and Exchange Commission or its staff upon request.</FONT></P>


<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="margin: 0"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 3pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0">&nbsp;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-97.1
<SEQUENCE>9
<FILENAME>e5240_ex97-1.htm
<DESCRIPTION>EXHIBIT 97.1
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 12pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="text-align: right; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>EXHIBIT 97.1</B></FONT></P>

<P STYLE="margin: 0; text-align: right"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; text-transform: uppercase"><B>ANAVEX
LIFE SCIENCES CORP.</B></FONT><B> <FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">NASDAQ RULE 5608<BR>
EXECUTIVE OFFICER COMPENSATION CLAWBACK <FONT STYLE="text-transform: uppercase">Policy</FONT></FONT></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; text-transform: uppercase"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; text-transform: uppercase"><B>Effective
</B></FONT><B><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">NOVEMBER 8<FONT STYLE="text-transform: uppercase">,
2023</FONT></FONT></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; text-transform: uppercase"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">1.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>Policy
Purpose</U>. The purpose of this Anavex Life Sciences Corp. Nasdaq Rule 5608 Executive Officer Compensation Clawback Policy (this &ldquo;<B><I>Policy</I></B>&rdquo;)
is to enable Anavex Life Sciences Corp. and its subsidiaries and affiliates (the &ldquo;<B><I>Company</I></B>&rdquo;) to recover Erroneously
Awarded Compensation in the event that the Company is required to prepare an Accounting Restatement. This Policy is intended to comply
with the requirements set forth in Listing Rule 5608 of The Nasdaq Stock Market LLC and will be construed and interpreted in accordance
with such intent. Unless otherwise defined in this Policy, capitalized terms will have the meaning ascribed to such terms in Section
7.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>Policy
Administration</U>. This Policy will be administered by the Compensation Committee of the Board (the &ldquo;<B><I>Committee</I></B>&rdquo;)
unless the Board determines to administer this Policy itself. The Committee has full and final authority to make all determinations under
this Policy, in each case to the extent permitted under the Listing Rule and in compliance with (or pursuant to an exemption from the
application of) Section 409A of the Code. All determinations and decisions made by the Committee pursuant to the provisions of this Policy
will be final, conclusive and binding on all persons, including the Company, its affiliates, its stockholders and the Executive Officers.
Any action or inaction by the Committee with respect to an Executive Officer under this Policy in no way limits the Committee&rsquo;s
actions or decisions not to act with respect to any other Executive Officer under this Policy or under any similar policy, agreement
or arrangement, nor will any such action or inaction serve as a waiver of any rights the Company may have against any Executive Officer
other than as set forth in this Policy.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>Policy
Application</U>. This Policy applies to all Incentive-Based Compensation received by a person (a) after beginning service as an Executive
Officer, (b) who served as an Executive Officer at any time during the performance period for such Incentive-Based Compensation, (c)
while the Company had a class of securities listed on a national securities exchange or a national securities association and (d) during
the three completed fiscal years immediately preceding the Accounting Restatement Date. In addition to such last three completed fiscal
years, the immediately preceding clause (d) includes any transition period that results from a change in the Company&rsquo;s fiscal year
within or immediately following such three completed fiscal years, provided that a transition period between the last day of the Company&rsquo;s
previous fiscal year end and the first day of its new fiscal year that comprises a period of nine to twelve months will be deemed a completed
fiscal year. For purposes of this Section 3, Incentive-Based Compensation is deemed received in the Company&rsquo;s fiscal period during
which the Financial Reporting Measure specified in the Incentive-Based Compensation award is attained, even if the payment or grant of
the Incentive-Based Compensation occurs after the end of that period. For the avoidance of doubt, Incentive-Based Compensation that is
subject to both a Financial Reporting Measure vesting condition and a service-based vesting condition will be considered received when
the relevant Financial Reporting Measure is achieved, even if the Incentive-Based Compensation continues to be subject to the service-based
vesting condition.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"></FONT></P>

<!-- Field: Page; Sequence: 1 -->
    <DIV STYLE="margin-top: 6pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><P STYLE="text-align: center; margin-top: 0pt; margin-bottom: 0pt"></P></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>Policy
Recovery Requirement</U>. In the event of an Accounting Restatement, the Company must recover, reasonably promptly, Erroneously Awarded
Compensation, in amounts determined pursuant to this Policy. The Company&rsquo;s obligation to recover Erroneously Awarded Compensation
is not dependent on if or when the Company files restated financial statements. Recovery under this Policy with respect to an Executive
Officer will not require the finding of any misconduct by such Executive Officer or such Executive Officer being found responsible for
the accounting error leading to an Accounting Restatement. In the event of an Accounting Restatement, the Company will satisfy the Company&rsquo;s
obligations under this Policy to recover any amount owed from any applicable Executive Officer by exercising its sole and absolute discretion
in how to accomplish such recovery, to the extent permitted under the Listing Rule and in compliance with (or pursuant to an exemption
from the application of) Section 409A of the Code. The Company&rsquo;s recovery obligation pursuant to this Section 4 will not apply
to the extent that the Committee, or in the absence of the Committee, a majority of the independent directors serving on the Board, determines
that such recovery would be impracticable and:</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">a.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
direct expense paid to a third party to assist in enforcing this Policy would exceed the amount to be recovered. Before concluding that
it would be impracticable to recover any amount of Erroneously Awarded Compensation based on expense of enforcement, the Company must
make a reasonable attempt to recover such Erroneously Awarded Compensation, document such reasonable attempts to recover and provide
that documentation to the Stock Exchange;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">b.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Recovery
would violate home country law where that law was adopted prior to November 28, 2022. Before concluding that it would be impracticable
to recover any amount of Erroneously Awarded Compensation based on violation of home country law, the Company must obtain an opinion
of home country counsel, acceptable to the Stock Exchange, that recovery would result in such a violation, and must provide such opinion
to the Stock Exchange; or</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">c.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Recovery
would likely cause an otherwise tax-qualified retirement plan, under which benefits are broadly available to employees of the registrant,
to fail to meet the requirements of Section 401(a)(13) or 411(a) of the Code.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>Policy
Prohibition on Indemnification and Insurance Reimbursement</U>. The Company is prohibited from indemnifying any current or former Executive
Officer against the loss of Erroneously Awarded Compensation. Further, the Company is prohibited from paying or reimbursing an Executive
Officer for purchasing insurance to cover any such loss.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>Required
Policy-Related Filings</U>. The Company will file all disclosures with respect to this Policy in accordance with the requirements of
the federal securities laws, including disclosures required by U.S. Securities and Exchange Commission filings.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">7.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>Definitions</U>.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">a.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&ldquo;<B><I>Accounting
Restatement</I></B>&rdquo; means an accounting restatement due to the material noncompliance of the Company with any financial reporting
requirement under the securities laws, including any required accounting restatement to correct an error in previously issued financial
statements that is material to the previously issued financial statements or that would result in a material misstatement if the error
were corrected in the current period or left uncorrected in the current period.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"></FONT></P>

<!-- Field: Page; Sequence: 2; Options: NewSection; Value: 2 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->2<!-- Field: /Sequence --></TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">b.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&ldquo;<B><I>Accounting
Restatement Date</I></B>&rdquo; means the earlier to occur of (i) the date the Board, a committee of the Board or the officers of the
Company authorized to take such action if the Board action is not required, concludes, or reasonably should have concluded, that the
Company is required to prepare an Accounting Restatement and (ii) the date a court, regulator or other legally authorized body directs
the Company to prepare an Accounting Restatement.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">c.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&ldquo;<B><I>Board</I></B>&rdquo;
means the board of directors of the Company.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">d.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&ldquo;<B><I>Code</I></B>&rdquo;
means the U.S. Internal Revenue Code of 1986, as amended. Any reference to a section of the Code or regulation thereunder includes such
section or regulation, any valid regulation or other official guidance promulgated under such section and any comparable provision of
any future legislation or regulation amending, supplementing, or superseding such section or regulation.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">e.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&ldquo;<B><I>Erroneously
Awarded Compensation</I></B>&rdquo; means, in the event of an Accounting Restatement, the amount of Incentive-Based Compensation previously
received that exceeds the amount of Incentive-Based Compensation that otherwise would have been received had it been determined based
on the restated amounts in such Accounting Restatement, and must be computed without regard to any taxes paid by the relevant Executive
Officer. Notwithstanding the foregoing, for Incentive-Based Compensation based on stock price or total stockholder return where the amount
of Erroneously Awarded Compensation is not subject to mathematical recalculation directly from the information in an Accounting Restatement
(i) the amount of Erroneously Awarded Compensation must be based on a reasonable estimate of the effect of the Accounting Restatement
on the stock price or total stockholder return upon which the Incentive-Based Compensation was received and (ii) the Company must maintain
documentation of the determination of that reasonable estimate and provide such documentation to the Stock Exchange.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">f.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&ldquo;<B><I>Executive
Officer</I></B>&rdquo; means the Company&rsquo;s president, principal financial officer, principal accounting officer (or if there is
no such accounting officer, the controller), any vice-president of the Company in charge of a principal business unit, division or function
(such as sales, administration or finance), any other officer who performs a policy-making function or any other person who performs
similar policy-making functions for the Company. An executive officer of the Company&rsquo;s parent or subsidiary is deemed an &ldquo;Executive
Officer&rdquo; if the executive officer performs such policy making functions for the Company.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">g.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&ldquo;<B><I>Financial
Reporting Measure</I></B>&rdquo; means any measure that is determined and presented in accordance with the accounting principles used
in preparing the Company&rsquo;s financial statements, and any measure that is derived wholly or in part from such measure, provided
that a Financial Reporting Measure is not required to be presented within the Company&rsquo;s financial statements or included in a filing
with the U.S. Securities and Exchange Commission to qualify as a &ldquo;Financial Reporting Measure.&rdquo; For purposes of this Policy,
&ldquo;Financial Reporting Measure&rdquo; includes, but is not limited to, stock price and total stockholder return.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"></FONT></P>

<!-- Field: Page; Sequence: 3; Value: 2 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->3<!-- Field: /Sequence --></TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">h.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&ldquo;<B><I>Incentive-Based
Compensation</I></B>&rdquo; means any compensation that is granted, earned or vested based wholly or in part upon the attainment of a
Financial Reporting Measure.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">i.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&ldquo;<B><I>Stock
Exchange</I></B>&rdquo; means the national stock exchange on which the Company&rsquo;s common stock is listed.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 72pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">8.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>Acknowledgement</U>.
Each Executive Officer will sign and return to the Company, within 30 calendar days following the later of (i) the effective date of
this Policy first set forth above or (ii) the date the individual becomes an Executive Officer, the Acknowledgement Form attached as
<U>Exhibit A</U>, pursuant to which the Executive Officer agrees to be bound by, and to comply with, the terms and conditions of this
Policy.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>Severability</U>.
The provisions in this Policy are intended to be applied to the fullest extent of the law. To the extent that any provision of this Policy
is found to be unenforceable or invalid under any applicable law, such provision will be applied to the maximum extent permitted, and
will automatically be deemed amended in a manner consistent with its objectives to the extent necessary to conform to any limitations
required under applicable law.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">10.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>Amendment
and Termination</U>. The Board may amend this Policy from time to time in its sole and absolute discretion and will amend this Policy
as it deems necessary to reflect the Listing Rule, to comply with (or maintain an exemption from the application of) Section&nbsp;409A
of the Code. The Board may terminate this Policy at any time.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">11.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>Other
Recovery Obligations and General Rights</U>. To the extent that the application of this Policy would provide for recovery of Incentive-Based
Compensation that the Company recovers pursuant to Section 304 of the Sarbanes-Oxley Act or other recovery obligations, the amount the
relevant Executive Officer has already reimbursed the Company will be credited to the required recovery under this Policy. This Policy
will not limit the rights of the Company to take any other actions or pursue other remedies that the Company may deem appropriate under
the circumstances and under applicable law, in each case to the extent permitted under the Listing Rule and in compliance with (or pursuant
to an exemption from the application of) Section 409A of the Code. Nothing contained in this Policy will limit the Company&rsquo;s ability
to seek recoupment, in appropriate circumstances (including circumstances beyond the scope of this Policy) and as permitted by other
applicable law, of any amounts from any individual, in each case to the extent permitted under the Listing Rule and in compliance with
(or pursuant to an exemption from the application of) Section 409A of the Code.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">12.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>Successors</U>.
This Policy is binding and enforceable against all Executive Officers and their beneficiaries, heirs, executors, administrators or other
legal representatives.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">13.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>Governing
Law and Venue</U>. This Policy and all rights and obligations hereunder are governed by and construed in accordance with the internal
laws of the State of Nevada, excluding any choice of law rules or principles that may direct the application of the laws of another jurisdiction.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"></FONT></P>

<!-- Field: Page; Sequence: 4; Value: 2 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 2pt solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->4<!-- Field: /Sequence --></TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR><TD STYLE="text-align: center; width: 100%">&nbsp;</TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 36pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>EXHIBIT
A</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; text-transform: uppercase"><B>ANAVEX
LIFE SCIENCES CORP.</B></FONT><B> <FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">NASDAQ RULE 5608<BR>
EXECUTIVE OFFICER C<FONT STYLE="text-transform: uppercase">ompensation CLAWBACK Policy</FONT></FONT></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; text-transform: uppercase"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; text-transform: uppercase"><B>Acknowledgement
Form</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; text-transform: uppercase"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">By
signing below, the undersigned acknowledges and confirms that the undersigned has received and reviewed a copy of the Anavex Life Sciences
Corp. Nasdaq Rule 5608 Executive Officer Compensation Clawback Policy (the &ldquo;<B><I>Policy</I></B>&rdquo;).</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">By
signing this Acknowledgement Form, the undersigned acknowledges and agrees that the undersigned is and will continue to be subject to
the Policy and that the Policy will apply both during and after the undersigned&rsquo;s employment with Anavex Life Sciences Corp. and,
as applicable, its subsidiaries and affiliates (the &ldquo;<B><I>Company</I></B>&rdquo;). Further, by signing below, the undersigned
agrees to abide by the terms of the Policy, including, without limitation, by returning any Erroneously Awarded Compensation (as defined
in the Policy) to the Company to the extent required by, and in a manner consistent with, the Policy.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 11pt Calibri, Helvetica, Sans-Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
<TD STYLE="width: 50%; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="padding: 0pt 0pt 0pt 10pt; width: 50%; text-align: justify; text-indent: -10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>EXECUTIVE
OFFICER</B></FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="padding: 0pt 0pt 0pt 10pt; border-bottom: black 1pt solid; text-align: justify; text-indent: -10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="padding: 0pt 0pt 0pt 10pt; text-align: justify; text-indent: -10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Signature</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="padding: 0pt 0pt 0pt 10pt; border-bottom: black 1pt solid; text-align: justify; text-indent: -10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="padding: 0pt 0pt 0pt 10pt; text-align: justify; text-indent: -10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Print
Name</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="padding: 0pt 0pt 0pt 10pt; border-bottom: black 1pt solid; text-align: justify; text-indent: -10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></TD>
<TD STYLE="padding: 0pt 0pt 0pt 10pt; text-align: justify; text-indent: -10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Date</FONT></TD></TR>
</TABLE>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;<FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 3pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>image_001.gif
<DESCRIPTION>GRAPHIC
<TEXT>
begin 644 image_001.gif
M1TE&.#EA# -! ?<  /______S/__F?__9O__,___ /_,___,S/_,F?_,9O_,
M,__, /^9__^9S/^9F?^99O^9,_^9 /]F__]FS/]FF?]F9O]F,_]F /\S__\S
MS/\SF?\S9O\S,_\S /\ __\ S/\ F?\ 9O\ ,_\  ,S__\S_S,S_F<S_9LS_
M,\S_ ,S,_\S,S,S,F<S,9LS,,\S, ,R9_\R9S,R9F<R99LR9,\R9 ,QF_\QF
MS,QFF<QF9LQF,\QF ,PS_\PSS,PSF<PS9LPS,\PS ,P _\P S,P F<P 9LP
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M,S.9 #-F_S-FS#-FF3-F9C-F,S-F #,S_S,SS#,SF3,S9C,S,S,S #, _S,
MS#, F3, 9C, ,S,   #__P#_S #_F0#_9@#_,P#_  #,_P#,S #,F0#,9@#,
M,P#,  "9_P"9S "9F0"99@"9,P"9  !F_P!FS !FF0!F9@!F,P!F   S_P S
MS  SF0 S9@ S,P S    _P  S   F0  9@  ,P
M
M
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MTBB-TNTWO9V2>^NG7/__UP4.38 V'0 #& @YO=,]C=.5Y]-!38 VJ-,U+8!
M;=0%.-1+K=,\W8$%>(%1K=1%+0._ =58+=59'8%3/1@:: 4$V(!@_=5$C7E>
M+=9A;=9I#<AK?=9J#8!OC=:*#,@\+=9U;=9WS=9S3<AP'0!7\']V#8!Z^-=]
MS=>-[(%X[8Z(C-A^S=.'K=B-W04H),D\/=DX?=B?S-<H1,J2C7DX/=F)O-F?
MK3:C#<K_)]J53=H\?7R<S=HX[=JGK=I=T*,K\-H8;=NU_7^NO=JWS=NUS=,W
MK=NR?=.^G=2Y/=N]G=._C=S+'=Q%/8#_Q]0V"  L0,@0"-W/+8%#G8!!_=?9
M_\W=1JV!#%AY#YB!#<B :F/5?<V "YC7+)#7ZHW6@BV"YYW78PV!8#W78RW?
M<MW?<8W7CL(=(YW,PN>*E:.N$"&0,N8Y/L?@-+=8-39?F--SB[5Q#%YC.5<Z
M;<.*D,4"',Y5%GY"D<6*#^[@(9YS'Y[A%Z[A&"Z+*^[@*=[B,5XZ*K[@$][B
M-![BGG7C&J[C.\?B/1[D%0[D$U[B'>XY91CB94A9,F#DK7CA/H[A/G[B/S[D
M5F[C/.?@3"[A.[[C%'[C42[D(D[E9 [E9G[C'Y[D%Q[C90[F:U[A,<[F;WY@
M:>[B: [A'\[E-=[E* [A-"[C<R[B?Q[G,.[G+W[G=/]NZ#8NZ(?>Y5S^6(N^
MX3)P!;V,%4V^-@=YDM0YX _QH&#,Q5U<GU/LPU4,PJ!^Q5;LP3_'?S,\PR'L
MQ:?.ZC?7PG)LPK:.Q*9^QJ0NZKN>Q2),ZK*.Q63<ZQ^<='''ZZZ.Q1W,PC],
MZZ7.ZW;LP:W.QM .[:J.ZJ(NQ\A>[':,ZLM.[=8^ZG7#?U&6[:'^[-5^ZM[N
MQE]L-TS\[<!U-XI6Q5'\P2W\ZKG.Z?6Q<>E8;RS+ A.Q=$1,QUMLHE6FQ)\>
MQDL\ZSC\[O@^\$*<Z]TNQNE>Q]C.P3=,Q1)?ZO6^\0W?Q,F>ZS"<QM<^\;5>
MZU7'\38,[+_>[#_,[!]?QF#_/&%>W/+:7G>K;NK3;NQM+,;:/O$F'^W$?O(]
M/\5,K/#R#L5X@_$@?+9:?/!H',8W#,0JS//>7F6X!>M"C,*XU>TM+W0PC1AE
MZ)9"2G9I2!&4K/.LOO'<'NZSWC8.(.QF3.YL#/'*CL8[3_%(;\/.OL-V'\-Q
MO,0O'_4RO/ T+/3-SO?9KNTC_\13#_AU7_%O/VAQC^XC;&;C3L8H[/=;O^I0
MW\9Y#_IU3/6B__/K/NTGO_?W7O2,[_E;_/7BKNY]4\0'W_<(3_LK_^LKS%)D
MINI0;_2;+^SN7OMN<P4 [R.%R ))NM'Z[A!I7\%GB,<3C+-THXX77,%P0XEO
M@V/O_W=T0QG!:LS#$#_^Y%_^YG_^Z)_^ZK_^[-_^ P]T>+=X>J-XDI/]ZZC]
MU7G]S)[X[M___O___P\0"00.)%C0X$&#"!0N9*A08$.($25"1%C18L6(+"1J
MW*CPP(&)("<BX"AR9,.'$:_( -#2Y4N8,67.I%G3YDV<. /L#) 3IQ49#0.
M#*"P*(NB"(86'8J *,, +$!^=&K4HU&.5Y5ZI%K4I-2C23^:E'C1[%FT:=6N
M9=O6+<&%28<BU;A3*LFI"NMN/>#58]:\(%EHG#J6(5FF6^4R3.#P[6/(D25/
M3CF1,N63C*'*/8#4JF?/2:UZ)4J5I-6\+0X;%CVZZE;'$O^O6/%9V_9MW"T_
M#MW=NR_OECW'\AR^M&_QW3!!-FZL]*E7I,^+!BVM%&G8P7SS.C]\^K5HOU(_
M@HU+$6YF].G5KV??WOW[]6.C6Y<_/FK>O7<%OR9\^NA5T@2C2R.ZG+OK-00&
M@B\SM18<J4$'RX(PHLLJ-,NA[KB[KZ\#J_./*[W(VBJ_J^2383SKG.JLO-@2
MA.O$W&*4<48 QK+Q1JE6Z*O&&FWDS3 5Q1M+1YB*4I [H_IRSB[>M#INH=^R
M(VVHYAK:;SNJ1*I+22@19*RR",,4<TPRRURJJKF,$X\DT;;,BJ.LG"H)P!#)
M6A$ZYT[TKL4R^_3SSP6/1,E"0@__2C#$,XF*ZDP5V5S(S0R[#+'1ID!3$<6/
M@MK314.5HO%34'WZJ$?>=O+Q )=^(VZI4G_[+:;!'FHLJ190M"ZZ^_QB,R_2
M8&-SL1&[XJHT\/!2\C@1 55V66;)%&RL$W7-U:KR_MLKTHP&^\I7--'LKUEP
MPUTV(?,$18^Y0]%%M[VTNHNN,U-%\@I8UUB@KC5NW=666L6Z]1(A-D,5>."9
M>.K)8(151;C4>'NJJ8L9JESHH>S<V\_+B272$J(Y-TWV0;0 ;??/D?T,^21[
MRS1)4P;=*SF]E\LDE#W)Q(6Y78G?9(AEO3*R>= J%;R"!8*+)CBJ%>S=C\#3
MI-(6VCBA_Y2*IBYX;@[,0UO.>*$9LF:H:W776Y<B3@LU^VRT9WY@H;7YQ-#K
ME)I[X*&V$UB[L;LU0\"!N?MN,6CFXI8U;<(++_1+<AT[^6:S+9/X<7/5!?MM
MQ5U4/&RX):X<HI6,]CS457_TS4?C3K6QII7233?H+[?6S%!9WP[\2+C457!P
MH W7?7?>$ZK]]ZPO4OWVN(=G?7;+5[^Z=^:;G[#L@A"?$,S!U[K\PD'+7IW3
MV**G?G;O?3=O8JP7ZOQS]-,?."E!(0_?<O"O!_[ZUHO'$/?J <:_]ON7A]_X
M_PEN>_P+'/=B=\#@)0]_VC,@_&(W0/]U;W_("Z#V\E>9W^FO@?_KPEWPO+>U
M_<D/>@5L( ,W&#_;";"#8<.<\@@X/.5QSX49(R$%6T<^@,GO>. 3(/F,)[A.
M0:]RM//A!8G'PP[^+7Q78V#U_O<W!,!(?5.D8F[P)2[-:>YG6^1B%[WX13"&
M48QC)&,9U8.J*J91C3=AP16NT+4VNC$H<5S)8-R8.CK*P(YRW&,=Z0C'.^HQ
MCWT<3!Y)$L@^"O*.A0SD(=W(R$<24I)TA.30)"F#149QD9=$)"8CZ4E+4M)>
MFP3E8$K)R4^Z<0:F)&4K4_E&5K[2DJ>DI2MGN<D9J#*6MX3E*".92U@B )BK
M]"4Q@6G)80XFF2Q89C/YR$Q=0M./SIS_9C27B4AI"A*8VHPF-KWYS&TF4IR#
MS.8XOXG'<RHRDN1,ISGE>,A<JM./Z73D/->Y24K6LY*[W*<F9<E/7P[-G\04
M91QILT:$)M0E<;P.,)42@%QVX:$.W0E%(>K&A]YQHA@=BD8[RM&+7B&C'#V
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M\YK3V]YI!,0J#@$(*P1B%8!HR0JL8(455,'K51![%?YM!;-[W0HQ +O:&PZ
M #P\XI1N\J<UO>.),SGOZPYZW_W^=\ '7O"#)WSA#7]XQ"=>\7O7.]T93W?(
M8]SQS-:TW2L=^8A/?.YL?KSF;9[TH?<:T8Q>V]2KN()5[%OUASA$%0PN]G^S
M_=\&7T$,TN[U@,N9_^Q@?TG<(YZ &907 31H6YTIF !"X^T!#]"SW9"_?(+0
MX&HX'@CQD2]]\3[\Z8OG?O>]_WWPAU_\XP=_\@72-^E#(&)VDWZ"EC]H.U/?
MNM=__OF+;^<VLW]NU&]^_XFO7>-C/N<[/X'(,>N"@ +$,?@B/O>#/_8[/^FS
MFSR+/S;KL>L;-KY30,V30-)# -.C(BXX!"[PND"(@4"X.MJ3,]V3,]JK K!3
M@=IKN[!+.YB0._@3 *[YFAF @+:Q,X5@/AI0B*YY  &8G"(LOB%,D*YQD25\
M (BB ?8)OJ,C/RJL0BN\0BS,0BWL.044IAM#ER"TFT,)/@2DO^NKLQE(0_\!
M +XZ0P $;$,R;+,9P,'@B[NN"4(!8#YA"L*U2</@.Y3KJK[_,[XAQ+$$"4*'
MN,,T;,/&&,*'R+'AVS_KH[X'2$.[B9C@ T+T"T/HL\3@<[Y:\Y0/3)\0G+,5
MP+>MHSV98,&8>+N9L,$<JT0M.D0^-$3F:[.V24,G'+[F6,(O1(GAHX$E%$+1
M*, M/$9D3$9E7$9FY,(N/#\=4 H&O#%AQ$'D2\ Z,\0?]$6',$"'R#.NX<;)
M0<2NF4,(5(I%%,(PQ#$=: SJRT9$5+X?%,9R[,5L5(AWG)R\.9>%T$:VR9BN
M"<515)\J6(6#ZCI6$#@5+ &O&SB&#("D68$2@ +_%5P!B)2SBX0[&^2S=C0*
M7P1">#Q$7/S#113 XLO&DQP^+QQ&B%B^[6M&F(Q)F9Q)FO2[+I1"/*S$/=0N
M*<1&YAO"2NQ#AE# 1J1 ACC).43')61#ET1$YEL^/>1%Y-M#82PA/]Q'7A3"
M/;S#,!2(:,1'(?3%I61#+PQ&83K+HU1)@1S(]!'!AC. 0% !@V.!%8 "NJ3+
M%!P,.:-+BI0SBKS+P6B)C>2S F2,^,-&Y+NS1D1#-T1$&L#!'SS+!XA&NJ&<
MNIF;FLQ,S=Q,SNQ,^*LSZ .^(OP?J)1'T'2_Y5-)B#(^.(R_/AQ&1%1"L/3"
M/(0^R20R!*A-7#3+NS'$_P3XRLBL1'T$Q#;,/S',F]BD$+3LQ]@<Q@18P[/\
M-0CP0+9$GQ5@O4 XR*X;#"A@2!8H@;GT.H:,R.[T2XE,&KP$@,%4M]04B%JC
M0,5D/^+#Q5L,3?K4,P$T1CN#2OC*.<_\3P -4 %5O.:+OO^+P/R40/LCP('@
M0?XK+^N#0 ?]/R"43^D[T @4Q*8L0^V[,R LPUB$O_+:P/K+S_J4RJ?DP>*+
M0!5]RJ5,OJ>$K]*,-5&LSL]A.^U,08E\2-I[R!*X2(N$R!(8TO&<LSH#/;P#
MN44#- QT/(M3M"9]R0&=4BJM4BO=/,A[/+W3TBF\.U2[/(H#TR4U-##M/&4S
MNO]6T[YU:S]X1%/K<T/+XS'V8[0:M='3<T67"+N",[B<B#O\$SHE?3HIO5)"
M+51#/51 1=3!FT+#JU,[G2(K@$$7E+.U&[O8 SO;F]2"R<:Y:S;1>](Q;39C
MD])05513/57"*U4LY3R.*U/IM#EH*SJ+:SICR[R?"U4Q'514_3ZC>[-'K:*R
MR[U_P[T5##M*K;U-I<8U6U9F;59G?59HC59IG59JK59KO59LS59M%3)?_=4I
M8CAC1;B*'-<J4#B:N"(S2E=U75=V;5=W?5=XC5<RJC=O/3U5[+I[!0!SM8F%
MZ5=__5> #5B!'5B"+5B#/5B$35B%75B&;5B'?5B(C5C_B9U8BJU8GB@8>JU7
MC:T)@]E8CVT)O6@!@=#%Y9,!D\W$&6@!%F@!E5U9EGU9EBU9&6!995J^E'U9
M_B2HP7A9DS79%DA#EDW#GAU:/RQ:HSU:I$U:I5U:IFU:IWU:J(U:J9U:JJU:
MJ[U:K(W:H=W:GG4 !["QH.79%IA9ECW93,S93 S:2AQ;&5@^4Y(!OBE;/1+9
MM=W9L?5#G_W9H76 E%W9!Z!9L@U;F/W9ETW9E)6QCTU<Q5W<FR@*9=U6R(U<
MR9U<RJU<R^TQ+KU<;J5.QNU<SU5</]7571U=TBW=H#NV"(@ F0S"C/U<UWW=
MW(#!&)!+S_$]J#-=W,U=W4W4_SM37<'S7='5.4>%7>(M7II0 4# SJVCW6$-
M.',]118\UN=EN-Y;3\S-7&5[MES%W)B+T]W]7O!%TC45/5>E./)5-UM=4S=U
M.<GSL<US-!T -NI4.#Q=Q7RM#5;,B0.H7Y=HW52IB?S-#17\%(A<Q0 .#N.E
MB1.\.BXXP4!H"=E30;0K.[%#.THE.]C[NK>S7<),32&\OPC2OAZ4Q$<4OD.L
M$@'$1ZXD'O\,7Q<FW6%S0Q+6PU],D#9KS(GA,Y%$OHBIRD^4/X= /S$\/UJ,
MP--,3#:-Q&[,OQ.&Q^NS- ]<@>SDO58\*!*DXIG 8I?XNJSC7YB8C:R3B;9[
MB?SUXO\ISM&6T&(%YN*< +N#HF*U"X2&X^*O"SBY;$@O)MZ"U+?5:[W74\%,
M/3@YL[VV<V/=T^#J)3W18,DT9$"SI$JM%,I9^4.MM$=[]$@H#,?@?6%.KE+B
MP\$@+,E==.0OS,,@M+$CQ;&BD+X\O,,$B+M:U.3[PQ"PP;$Z3$)J+,M<#,8P
M;$.A-&4Z-;B#E(&O$V8Y>^ M[CHWYCT-EL&7X#VO P -QF,L?N-CE>8NIE0W
MEF-$1N0MMN9F;KOLC*YI]F9I3F.U8V9LMF+:>&-WOE>WV^*!:^<$C@DN,$@5
MJ (YUCJN&U<\3D$9Q.,8/. .G<"(V1Y:=&(@).6(64,VE1O_1_Y'/U0(.FR-
M)^YDC"[4BX-$H3Q+-OU)WA0FDZA0(;3'KE$-!%W.&U-*%_%A Z2_(O3'TW3B
MJ3Q$7:91@YMB ) !*9;B)Z#49VX).6Y(;B:!L,M.F/BZ?:.]KYO4?9XS/>#B
MG@Z$)Z -;M;FAM0#$K""J@8 U]MBVE7JL+."K6[F?'X"0.AIKFL)/4CC+F;F
MJI9B93YG:7Z"+<8Z>;:"+BCF*YAG:<[CUVW@4]175.SG^CU@N -L];2U=WQ.
ML;SA"D5B663,!&6;COR:K?2:B7')C.YL5*W&W"3+J'3HM=$SBH8C?-1&.JPS
MQ\5!4_[@E63=&W/)0K3I01O+H0S*_]6)QV@4P'*+XH.4:K?33G7VNJHN9FG&
MZV>6LW[FXI]6@:M&YX$#A.-NYX84[A6P:T0F@6?^:K2CC9_&9G(V;C>F:[HN
M;V;FO;4N9F3F:GS%YC3^:Y?8 _ L9C5.X(+4SA5(2!U-&MY#"HN,R+I4P>]<
M2!;TO5B+P,O^1CZ\822.Y"!T\,>4Z'LDSLI8RO?S; U'U AL/SST\-(N[0+L
MQ4)<FQNVZ7DL3"6>&[ I1!RSQA/US53>PZQ9FUL<PT,Q1/D5YI8H@:<&NWU^
MYH*C#6+N:3IVNSE+;SIF9J_;TX.\[CA.YW"V[KT>8Z%F8X$[8W+^.A.,YH,\
MXW-> 3".X_^YSKHPIM3L'$&@IF.&S,ZXE&;NKN>7"(2T=@FX++@!M\N(S,MQ
M+<\!WTN[U,@65L#^)+Y#RW#CU,3[+$W]V[.GU#_AU,4&W>0-KW28G$\%;+6F
MC%%,Q[[DZW2H%,8-Y70.W?2%GG3\M&4)S'3\;,(^0[]-_--"X]P\9453)./W
M'F ^S=/[7CB8(!+=>(G]K76X@^<Y0Y7H?3M;-^96?#LT2D$$ICV(M((V2N9\
M[0E=GS/Z-4531.-ZAFZK6^M:%_!D%\^*]'.ZW$N\+ J=6]*=&U-W9]4X=5]+
MKW="9=17332C8S4TM;;U;=6EZ[@DU;R!S[3AE?-F%YAX[CK%S@G_Q$;X&?QU
M%=P);B]C6_]1\!Q/0:=T>^]XC^_D;D5XD1]Y:*[BA=O379<)!/]XEF_YCP_Y
MD8]Y_,9JV<-@V<-4'.5?Q]5<GN]YG_]YH ]ZH3<RF)=YHW_=V+/C88W4LSO6
MAHR!<[T1J8\7J:]ZTA$=5[%ZK=]ZKN]ZK_]ZL ][L1][LB][LS][M$][M5][
MMF][MV=[T?'?HY][QAVX84TX?X9!%=Q7E;=8O_][P ]\P1]\PB]\PS]\Q/_[
MWD.8&=F):#]8G8 [?PV.CJ5\RY?\?^W[BZ7\@W&8S:^-RJ=[G)!+VGWOT@>
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M<81 <COR:) *JQQR2"!<)+8*8S%@%X-V5F!G@':'*9G=8M=1!QD 4V7_]$
M["$P Y<)S###1@.*1.9%['DY@P!>!C:#?&"FER*7$+*G99A;IC=#@WORV:>?
M?P(*4UXS"G!?>@*&*4"&Z(F90*%L"AB@EUT^4*B  @K 6Y<"HAG?@)]^ZF6
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MOVXNV^RA8;K7M)MN)BNOM)-ZB^'#9T=EQ2$Q$!0#*[IJ5T+'*Y2@<6./<0Q
MW7HOM?>6S&;5X7HOELELAS/&J:F)3]];=%+GY?>N?A,!7;GEEV.N((4QTAF
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M 1:Q\T#C[JP%AWXN$1J-4?OF,VWM:3+W<T1;& E4P7N:[Y(*!(3&DMPE6EE
M0 T<\#V#DBC5,Q,5Z4FC=$I3FT9 M$2[M'Q5 1KKP3,7QEJ]Z4W':0JV*9U*
M(4\KZ$\#=5 +]5 3=5%/H8N^=%+/UR[ZIA)+A4I="<9*]513=54K%-IP)$1D
MM:0-QE8[!%)/;!1YM4",=52X:%G7YXZ@=5K3F2(6AD0Q*5Q?U)+.-5P[J5W;
M]4#I=5['=9+RM5X#MI,&MF WZ5_W-6$C=F(K]F(S=F,[]F-#=F1+]F0W_W8
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E-#.B*,J@)KJB+I.B+MJ;+!JCR_6B*"JC-GHQ-%JC-VIK 0$ .P$!

end
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>image_002.gif
<DESCRIPTION>GRAPHIC
<TEXT>
begin 644 image_002.gif
M1TE&.#EA# ,' O<  /______S/__F?__9O__,___ /_,___,S/_,F?_,9O_,
M,__, /^9__^9S/^9F?^99O^9,_^9 /]F__]FS/]FF?]F9O]F,_]F /\S__\S
MS/\SF?\S9O\S,_\S /\ __\ S/\ F?\ 9O\ ,_\  ,S__\S_S,S_F<S_9LS_
M,\S_ ,S,_\S,S,S,F<S,9LS,,\S, ,R9_\R9S,R9F<R99LR9,\R9 ,QF_\QF
MS,QFF<QF9LQF,\QF ,PS_\PSS,PSF<PS9LPS,\PS ,P _\P S,P F<P 9LP
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M,S.9 #-F_S-FS#-FF3-F9C-F,S-F #,S_S,SS#,SF3,S9C,S,S,S #, _S,
MS#, F3, 9C, ,S,   #__P#_S #_F0#_9@#_,P#_  #,_P#,S #,F0#,9@#,
M,P#,  "9_P"9S "9F0"99@"9,P"9  !F_P!FS !FF0!F9@!F,P!F   S_P S
MS  SF0 S9@ S,P S    _P  S   F0  9@  ,P
M
M
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M^)=_P5=MV@=_RH: ":AZWJ=R=Q>!>E=[+L=\U6!ZR " P/"!( @,P1 ,T$>
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M]"N$&SFL ZN@%4NF=:JLYKF!SH#!U%NJX&NX"+NM%ZN?P$"LL%JP**  4KL
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M+:;S/=FK/+$K)+MCIX$H(=TP/EW3MPE$L0%$"(:(KA4J-01L"'9JDKI2NK&
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MO"LE?V3^J@^=\-'J5D0;_ZPA%ZX;L6I>Q&,BFVM4A/)+,!);K*49)\-C+@X
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MU/%=A(UAB4PCC';:[J;#_S36:3/L:O7I\YPG3<MHMN0I_9@L;'DNT":L.@'
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1]MILM^WVVW#'+??<:@<$ #L!

end
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.SCH
<SEQUENCE>12
<FILENAME>avxl-20230930.xsd
<DESCRIPTION>XBRL SCHEMA FILE
<TEXT>
<XBRL>
<?xml version="1.0" encoding="US-ASCII" ?>
    <!-- Field: Doc-Info; Name: Generator; Value: GoXBRL; Version: 5.20c -->
    <!-- Field: Doc-Info; Name: VendorURI; Value: https://www.novaworks.com -->
    <!-- Field: Doc-Info; Name: Status; Value: 0x00000000 -->
    <!-- Field: Doc-Info; Name: Misc; Value: 8Kk5s7xRiXgOn8uCbX9cOaCFKaOdyJV+eYkxt25/bTlqDy4uyTgGDChAIHnGIUMK -->
<schema xmlns="http://www.w3.org/2001/XMLSchema" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:xbrldi="http://xbrl.org/2006/xbrldi" xmlns:dei="http://xbrl.sec.gov/dei/2023" xmlns:us-gaap="http://fasb.org/us-gaap/2023" xmlns:srt="http://fasb.org/srt/2023" xmlns:srt-types="http://fasb.org/srt-types/2023" xmlns:dtr-types="http://www.xbrl.org/dtr/type/2022-03-31" xmlns:avxl="http://anavex.com/20230930" elementFormDefault="qualified" targetNamespace="http://anavex.com/20230930">
    <annotation>
      <appinfo>
        <link:roleType roleURI="http://anavex.com/role/Cover" id="Cover">
          <link:definition>00000001 - Document - Cover</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/BalanceSheets" id="BalanceSheets">
          <link:definition>00000002 - Statement - Consolidated Balance Sheets</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/BalanceSheetsParenthetical" id="BalanceSheetsParenthetical">
          <link:definition>00000003 - Statement - Consolidated Balance Sheets (Parenthetical)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss" id="StatementsOfOperationsAndComprehensiveLoss">
          <link:definition>00000004 - Statement - Consolidated Statements of Operations and Comprehensive Loss</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/StatementsOfOperationsAndComprehensiveLossParenthetical" id="StatementsOfOperationsAndComprehensiveLossParenthetical">
          <link:definition>00000005 - Statement - Consolidated Statements of Operations and Comprehensive Loss (Parenthetical)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/StatementsOfCashFlows" id="StatementsOfCashFlows">
          <link:definition>00000006 - Statement - Consolidated Statements of Cash Flows</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/StatementsOfChangesInStockholdersEquity" id="StatementsOfChangesInStockholdersEquity">
          <link:definition>00000007 - Statement - Consolidated Statements of Changes in Stockholders' Equity</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/BusinessDescriptionAndBasisOfPresentation" id="BusinessDescriptionAndBasisOfPresentation">
          <link:definition>00000008 - Disclosure - Business Description and Basis of Presentation</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/SummaryOfSignificantAccountingPolicies" id="SummaryOfSignificantAccountingPolicies">
          <link:definition>00000009 - Disclosure - Summary of Significant Accounting Policies</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/AccruedLiabilities" id="AccruedLiabilities">
          <link:definition>00000010 - Disclosure - Accrued Liabilities</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/OtherIncome" id="OtherIncome">
          <link:definition>00000011 - Disclosure - Other Income</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/EquityOfferings" id="EquityOfferings">
          <link:definition>00000012 - Disclosure - Equity Offerings</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/CommitmentsAndContingencies" id="CommitmentsAndContingencies">
          <link:definition>00000013 - Disclosure - Commitments and Contingencies</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/IncomeTaxes" id="IncomeTaxes">
          <link:definition>00000014 - Disclosure - Income Taxes</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/SubsequentEvents" id="SubsequentEvents">
          <link:definition>00000015 - Disclosure - Subsequent Events</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies" id="SummaryOfSignificantAccountingPoliciesPolicies">
          <link:definition>00000016 - Disclosure - Summary of Significant Accounting Policies (Policies)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/AccruedLiabilitiesTables" id="AccruedLiabilitiesTables">
          <link:definition>00000017 - Disclosure - Accrued Liabilities (Tables)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/CommitmentsAndContingenciesTables" id="CommitmentsAndContingenciesTables">
          <link:definition>00000018 - Disclosure - Commitments and Contingencies (Tables)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/IncomeTaxesTables" id="IncomeTaxesTables">
          <link:definition>00000019 - Disclosure - Income Taxes (Tables)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/SummaryOfSignificantAccountingPoliciesDetailsNarrative" id="SummaryOfSignificantAccountingPoliciesDetailsNarrative">
          <link:definition>00000020 - Disclosure - Summary of Significant Accounting Policies (Details Narrative)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/AccruedLiabilitiesDetails" id="AccruedLiabilitiesDetails">
          <link:definition>00000021 - Disclosure - Accrued Liabilities (Details)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/OtherIncomeDetailsNarrative" id="OtherIncomeDetailsNarrative">
          <link:definition>00000022 - Disclosure - Other Income (Details Narrative)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/EquityOfferingsDetailsNarrative" id="EquityOfferingsDetailsNarrative">
          <link:definition>00000023 - Disclosure - Equity Offerings (Details Narrative)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails" id="CommitmentsAndContingenciesDetails">
          <link:definition>00000024 - Disclosure - Commitments and Contingencies (Details)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails1" id="CommitmentsAndContingenciesDetails1">
          <link:definition>00000025 - Disclosure - Commitments and Contingencies (Details 1)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails2" id="CommitmentsAndContingenciesDetails2">
          <link:definition>00000026 - Disclosure - Commitments and Contingencies (Details 2)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails3" id="CommitmentsAndContingenciesDetails3">
          <link:definition>00000027 - Disclosure - Commitments and Contingencies (Details 3)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails4" id="CommitmentsAndContingenciesDetails4">
          <link:definition>00000028 - Disclosure - Commitments and Contingencies (Details 4)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails5" id="CommitmentsAndContingenciesDetails5">
          <link:definition>00000029 - Disclosure - Commitments and Contingencies (Details 5)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails6" id="CommitmentsAndContingenciesDetails6">
          <link:definition>00000030 - Disclosure - Commitments and Contingencies (Details 6)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative" id="CommitmentsAndContingenciesDetailsNarrative">
          <link:definition>00000031 - Disclosure - Commitments and Contingencies (Details Narrative)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/IncomeTaxesDetails" id="IncomeTaxesDetails">
          <link:definition>00000032 - Disclosure - Income Taxes (Details)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/IncomeTaxesDetails1" id="IncomeTaxesDetails1">
          <link:definition>00000033 - Disclosure - Income Taxes (Details 1)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/IncomeTaxesDetails2" id="IncomeTaxesDetails2">
          <link:definition>00000034 - Disclosure - Income Taxes (Details 2)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:roleType roleURI="http://anavex.com/role/IncomeTaxesDetailsNarrative" id="IncomeTaxesDetailsNarrative">
          <link:definition>00000035 - Disclosure - Income Taxes (Details Narrative)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
        </link:roleType>
        <link:linkbaseRef xlink:type="simple" xlink:href="avxl-20230930_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:title="Presentation Links" />
        <link:linkbaseRef xlink:type="simple" xlink:href="avxl-20230930_lab.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:title="Label Links" />
        <link:linkbaseRef xlink:type="simple" xlink:href="avxl-20230930_cal.xml" xlink:role="http://www.xbrl.org/2003/role/calculationLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:title="Calculation Links" />
        <link:linkbaseRef xlink:type="simple" xlink:href="avxl-20230930_def.xml" xlink:role="http://www.xbrl.org/2003/role/definitionLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:title="Definition Links" />
      </appinfo>
    </annotation>
    <import namespace="http://www.xbrl.org/2003/instance" schemaLocation="http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd" />
    <import namespace="http://www.xbrl.org/2003/linkbase" schemaLocation="http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" />
    <import namespace="http://xbrl.sec.gov/dei/2023" schemaLocation="https://xbrl.sec.gov/dei/2023/dei-2023.xsd" />
    <import namespace="http://fasb.org/us-gaap/2023" schemaLocation="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd" />
    <import namespace="http://fasb.org/us-types/2023" schemaLocation="https://xbrl.fasb.org/us-gaap/2023/elts/us-types-2023.xsd" />
    <import namespace="http://www.xbrl.org/dtr/type/2022-03-31" schemaLocation="https://www.xbrl.org/dtr/type/2022-03-31/types.xsd" />
    <import namespace="http://xbrl.sec.gov/country/2023" schemaLocation="https://xbrl.sec.gov/country/2023/country-2023.xsd" />
    <import namespace="http://xbrl.sec.gov/currency/2023" schemaLocation="https://xbrl.sec.gov/currency/2023/currency-2023.xsd" />
    <import namespace="http://fasb.org/srt/2023" schemaLocation="https://xbrl.fasb.org/srt/2023/elts/srt-2023.xsd" />
    <import namespace="http://fasb.org/srt-types/2023" schemaLocation="https://xbrl.fasb.org/srt/2023/elts/srt-types-2023.xsd" />
    <element id="avxl_MichaelJFoxFoundationMember" name="MichaelJFoxFoundationMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_SecuritiesPurchaseAgreementMember" name="SecuritiesPurchaseAgreementMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_EquityOfferingSalesAgreementMember" name="EquityOfferingSalesAgreementMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_PurchaseAgreement2023Member" name="PurchaseAgreement2023Member" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_LincolnParkCapitalFundLLCMember" name="LincolnParkCapitalFundLLCMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_CommonStockIncludingCommitmentSharesMember" name="CommonStockIncludingCommitmentSharesMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_CommonStockExcludingCommitmentSharesMember" name="CommonStockExcludingCommitmentSharesMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_CommitmentSharesMember" name="CommitmentSharesMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_PurchaseAgreement2019Member" name="PurchaseAgreement2019Member" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_StockOptionPlan2015Member" name="StockOptionPlan2015Member" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_StockOptionPlan2019Member" name="StockOptionPlan2019Member" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_StockOptionPlan2022Member" name="StockOptionPlan2022Member" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_PurchaseWarrants1Member" name="PurchaseWarrants1Member" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_PurchaseWarrants2Member" name="PurchaseWarrants2Member" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_OptionPrice1Member" name="OptionPrice1Member" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_OptionPrice2Member" name="OptionPrice2Member" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_OptionPrice3Member" name="OptionPrice3Member" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_OptionPrice4Member" name="OptionPrice4Member" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_OptionPrice5Member" name="OptionPrice5Member" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_FederalMember" name="FederalMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_NonOperatingIncomeFromGrants" name="NonOperatingIncomeFromGrants" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_ResearchAndDevelopmentIncentiveIncome" name="ResearchAndDevelopmentIncentiveIncome" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_OtherFinancingExpense" name="OtherFinancingExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_EarningPerShareBasicAndDilutedAbstract" name="EarningPerShareBasicAndDilutedAbstract" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_NoncashFinancingRelatedCharges" name="NoncashFinancingRelatedCharges" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_DeferredGrantIncome" name="DeferredGrantIncome" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_CashPaidForStateAndLocalMinimumIncomeTaxes" name="CashPaidForStateAndLocalMinimumIncomeTaxes" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares" name="SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares" name="SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_CommitmentShares" name="CommitmentShares" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_CommitmentSharesShares" name="CommitmentSharesShares" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_SharesIssuedUnderSalesAgreement" name="SharesIssuedUnderSalesAgreement" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_SharesIssuedUnderSalesAgreementShares" name="SharesIssuedUnderSalesAgreementShares" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_LessSalesAgreementShareIssueCosts" name="LessSalesAgreementShareIssueCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_SharesIssuedPursuantToRegisteredDirectOffering" name="SharesIssuedPursuantToRegisteredDirectOffering" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_SharesIssuedPursuantToRegisteredDirectOfferingShares" name="SharesIssuedPursuantToRegisteredDirectOfferingShares" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_LessRegisteredDirectOfferingShareIssueCosts" name="LessRegisteredDirectOfferingShareIssueCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_SharesIssuedPursuantToExerciseOfStockOptions" name="SharesIssuedPursuantToExerciseOfStockOptions" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_SharesIssuedPursuantToExerciseOfStockOptionsShares" name="SharesIssuedPursuantToExerciseOfStockOptionsShares" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_SharesIssuedPusuantToExerciseOfWarrants" name="SharesIssuedPusuantToExerciseOfWarrants" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_SharesIssuedPusuantToExerciseOfWarrantsShares" name="SharesIssuedPusuantToExerciseOfWarrantsShares" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_DisclosureAccruedLiabilitiesAbstract" name="DisclosureAccruedLiabilitiesAbstract" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_AccuredLiabilitiesTextBlock" name="AccuredLiabilitiesTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_DisclosureOtherIncomeAbstract" name="DisclosureOtherIncomeAbstract" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_OtherIncomeDisclosureTextBlock" name="OtherIncomeDisclosureTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_DisclosureEquityOfferingsAbstract" name="DisclosureEquityOfferingsAbstract" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_EquityOfferingTextBlock" name="EquityOfferingTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_LicenseFeesPolicyTextBlock" name="LicenseFeesPolicyTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_GrantIncomePolicyTextBlock" name="GrantIncomePolicyTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock" name="ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock" name="ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_AccruedClinicalSiteAndPatientVisitsCosts" name="AccruedClinicalSiteAndPatientVisitsCosts" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_FixedContractAccruals" name="FixedContractAccruals" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_MilestoneBasedContractAccruals" name="MilestoneBasedContractAccruals" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_GrantIncome" name="GrantIncome" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_NonOperatingIncomeFromGrant" name="NonOperatingIncomeFromGrant" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_DeferredGrantIncome1" name="DeferredGrantIncome1" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_PercentageOfGrossProceedsFromSales" name="PercentageOfGrossProceedsFromSales" nillable="true" xbrli:periodType="duration" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_SoldForGrossProceedsAmount" name="SoldForGrossProceedsAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_SalesOfAgreementAmount" name="SalesOfAgreementAmount" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_ValueOfSharesObligatedToPurchase" name="ValueOfSharesObligatedToPurchase" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_NumberOfSharesObligatedToPurchaseProrataBasic" name="NumberOfSharesObligatedToPurchaseProrataBasic" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_FairValueOfInitialCommitment" name="FairValueOfInitialCommitment" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_IncurredExpenses" name="IncurredExpenses" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice" name="ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice" nillable="true" xbrli:periodType="duration" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice" name="ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice" nillable="true" xbrli:periodType="duration" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_WarrantsOutstandingWeightedAverageExercise" name="WarrantsOutstandingWeightedAverageExercise" nillable="true" xbrli:periodType="instant" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_OptionIssued" name="OptionIssued" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_DeferredTaxAssetsResearchAndDevelopmentCapitalization" name="DeferredTaxAssetsResearchAndDevelopmentCapitalization" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_DeferredTaxAssetsUnpaidCharges" name="DeferredTaxAssetsUnpaidCharges" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_PermanentDifferencesRelatingToStockBasedCompensation" name="PermanentDifferencesRelatingToStockBasedCompensation" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_PermanentDifferencesRelatingToSection162m" name="PermanentDifferencesRelatingToSection162m" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_AdjustmentToTaxAssetsBasedOnSection382" name="AdjustmentToTaxAssetsBasedOnSection382" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet" name="IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_OperatingLossCarryforwardsDescription" name="OperatingLossCarryforwardsDescription" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_OperatingLossCarryForwardsExpirationYear" name="OperatingLossCarryForwardsExpirationYear" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="avxl_ResearchAndDevelopmentTaxCreditsYear" name="ResearchAndDevelopmentTaxCreditsYear" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
</schema>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.CAL
<SEQUENCE>13
<FILENAME>avxl-20230930_cal.xml
<DESCRIPTION>XBRL CALCULATION FILE
<TEXT>
<XBRL>
<?xml version="1.0" encoding="US-ASCII" standalone="no"?>
    <!-- Field: Doc-Info; Name: Generator; Value: GoXBRL; Version: 5.20c -->
    <!-- Field: Doc-Info; Name: VendorURI; Value: https://www.novaworks.com -->
    <!-- Field: Doc-Info; Name: Status; Value: 0x00000000 -->
<link:linkbase xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrli="http://www.xbrl.org/2003/instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
    <link:roleRef roleURI="http://anavex.com/role/Cover" xlink:href="avxl-20230930.xsd#Cover" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/BalanceSheets" xlink:href="avxl-20230930.xsd#BalanceSheets" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/BalanceSheetsParenthetical" xlink:href="avxl-20230930.xsd#BalanceSheetsParenthetical" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss" xlink:href="avxl-20230930.xsd#StatementsOfOperationsAndComprehensiveLoss" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/StatementsOfOperationsAndComprehensiveLossParenthetical" xlink:href="avxl-20230930.xsd#StatementsOfOperationsAndComprehensiveLossParenthetical" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/StatementsOfCashFlows" xlink:href="avxl-20230930.xsd#StatementsOfCashFlows" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/StatementsOfChangesInStockholdersEquity" xlink:href="avxl-20230930.xsd#StatementsOfChangesInStockholdersEquity" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/BusinessDescriptionAndBasisOfPresentation" xlink:href="avxl-20230930.xsd#BusinessDescriptionAndBasisOfPresentation" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/SummaryOfSignificantAccountingPolicies" xlink:href="avxl-20230930.xsd#SummaryOfSignificantAccountingPolicies" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/AccruedLiabilities" xlink:href="avxl-20230930.xsd#AccruedLiabilities" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/OtherIncome" xlink:href="avxl-20230930.xsd#OtherIncome" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/EquityOfferings" xlink:href="avxl-20230930.xsd#EquityOfferings" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingencies" xlink:href="avxl-20230930.xsd#CommitmentsAndContingencies" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxes" xlink:href="avxl-20230930.xsd#IncomeTaxes" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/SubsequentEvents" xlink:href="avxl-20230930.xsd#SubsequentEvents" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:href="avxl-20230930.xsd#SummaryOfSignificantAccountingPoliciesPolicies" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/AccruedLiabilitiesTables" xlink:href="avxl-20230930.xsd#AccruedLiabilitiesTables" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesTables" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesTables" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxesTables" xlink:href="avxl-20230930.xsd#IncomeTaxesTables" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/SummaryOfSignificantAccountingPoliciesDetailsNarrative" xlink:href="avxl-20230930.xsd#SummaryOfSignificantAccountingPoliciesDetailsNarrative" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/AccruedLiabilitiesDetails" xlink:href="avxl-20230930.xsd#AccruedLiabilitiesDetails" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/OtherIncomeDetailsNarrative" xlink:href="avxl-20230930.xsd#OtherIncomeDetailsNarrative" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/EquityOfferingsDetailsNarrative" xlink:href="avxl-20230930.xsd#EquityOfferingsDetailsNarrative" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails1" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails1" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails2" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails2" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails3" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails3" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails4" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails4" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails5" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails5" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails6" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails6" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetailsNarrative" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxesDetails" xlink:href="avxl-20230930.xsd#IncomeTaxesDetails" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxesDetails1" xlink:href="avxl-20230930.xsd#IncomeTaxesDetails1" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxesDetails2" xlink:href="avxl-20230930.xsd#IncomeTaxesDetails2" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxesDetailsNarrative" xlink:href="avxl-20230930.xsd#IncomeTaxesDetailsNarrative" xlink:type="simple" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/Cover" xlink:title="00000001 - Document - Cover" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/BalanceSheets" xlink:title="00000002 - Statement - Consolidated Balance Sheets">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_Assets" xlink:label="loc_us-gaapAssets" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaapCashAndCashEquivalentsAtCarryingValue" />
      <link:calculationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssets" xlink:to="loc_us-gaapCashAndCashEquivalentsAtCarryingValue" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxesReceivable" xlink:label="loc_us-gaapIncomeTaxesReceivable" />
      <link:calculationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssets" xlink:to="loc_us-gaapIncomeTaxesReceivable" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="loc_us-gaapPrepaidExpenseAndOtherAssetsCurrent" />
      <link:calculationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssets" xlink:to="loc_us-gaapPrepaidExpenseAndOtherAssetsCurrent" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_Liabilities" xlink:label="loc_us-gaapLiabilities" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccountsPayableCurrent" xlink:label="loc_us-gaapAccountsPayableCurrent" />
      <link:calculationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilities" xlink:to="loc_us-gaapAccountsPayableCurrent" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="loc_us-gaapAccruedLiabilitiesCurrent" />
      <link:calculationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilities" xlink:to="loc_us-gaapAccruedLiabilitiesCurrent" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredRentCredit" xlink:label="loc_us-gaapDeferredRentCredit" />
      <link:calculationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilities" xlink:to="loc_us-gaapDeferredRentCredit" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaapStockholdersEquity" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PreferredStockValue" xlink:label="loc_us-gaapPreferredStockValue" />
      <link:calculationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapStockholdersEquity" xlink:to="loc_us-gaapPreferredStockValue" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockValue" xlink:label="loc_us-gaapCommonStockValue" />
      <link:calculationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapStockholdersEquity" xlink:to="loc_us-gaapCommonStockValue" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AdditionalPaidInCapitalCommonStock" xlink:label="loc_us-gaapAdditionalPaidInCapitalCommonStock" />
      <link:calculationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapStockholdersEquity" xlink:to="loc_us-gaapAdditionalPaidInCapitalCommonStock" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaapRetainedEarningsAccumulatedDeficit" />
      <link:calculationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapStockholdersEquity" xlink:to="loc_us-gaapRetainedEarningsAccumulatedDeficit" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="loc_us-gaapLiabilitiesAndStockholdersEquity" />
      <link:calculationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesAndStockholdersEquity" xlink:to="loc_us-gaapLiabilities" xlink:type="arc" weight="1" />
      <link:calculationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesAndStockholdersEquity" xlink:to="loc_us-gaapStockholdersEquity" xlink:type="arc" weight="1" />
    </link:calculationLink>
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/BalanceSheetsParenthetical" xlink:title="00000003 - Statement - Consolidated Balance Sheets (Parenthetical)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss" xlink:title="00000004 - Statement - Consolidated Statements of Operations and Comprehensive Loss">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingExpenses" xlink:label="loc_us-gaapOperatingExpenses" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_GeneralAndAdministrativeExpense" xlink:label="loc_us-gaapGeneralAndAdministrativeExpense" />
      <link:calculationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingExpenses" xlink:to="loc_us-gaapGeneralAndAdministrativeExpense" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ResearchAndDevelopmentExpense" xlink:label="loc_us-gaapResearchAndDevelopmentExpense" />
      <link:calculationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingExpenses" xlink:to="loc_us-gaapResearchAndDevelopmentExpense" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaapOperatingIncomeLoss" />
      <link:calculationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingIncomeLoss" xlink:to="loc_us-gaapOperatingExpenses" xlink:type="arc" weight="-1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NonoperatingIncomeExpense" xlink:label="loc_us-gaapNonoperatingIncomeExpense" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_NonOperatingIncomeFromGrants" xlink:label="loc_avxlNonOperatingIncomeFromGrants" />
      <link:calculationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNonoperatingIncomeExpense" xlink:to="loc_avxlNonOperatingIncomeFromGrants" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ResearchAndDevelopmentIncentiveIncome" xlink:label="loc_avxlResearchAndDevelopmentIncentiveIncome" />
      <link:calculationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNonoperatingIncomeExpense" xlink:to="loc_avxlResearchAndDevelopmentIncentiveIncome" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InterestIncomeExpenseNet" xlink:label="loc_us-gaapInterestIncomeExpenseNet" />
      <link:calculationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNonoperatingIncomeExpense" xlink:to="loc_us-gaapInterestIncomeExpenseNet" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OtherFinancingExpense" xlink:label="loc_avxlOtherFinancingExpense" />
      <link:calculationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNonoperatingIncomeExpense" xlink:to="loc_avxlOtherFinancingExpense" xlink:type="arc" weight="-1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ForeignCurrencyTransactionGainLossBeforeTax" xlink:label="loc_us-gaapForeignCurrencyTransactionGainLossBeforeTax" />
      <link:calculationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNonoperatingIncomeExpense" xlink:to="loc_us-gaapForeignCurrencyTransactionGainLossBeforeTax" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:label="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" />
      <link:calculationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:to="loc_us-gaapOperatingIncomeLoss" xlink:type="arc" weight="1" />
      <link:calculationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:to="loc_us-gaapNonoperatingIncomeExpense" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaapNetIncomeLoss" />
      <link:calculationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetIncomeLoss" xlink:to="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CurrentIncomeTaxExpenseBenefit" xlink:label="loc_us-gaapCurrentIncomeTaxExpenseBenefit" />
      <link:calculationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetIncomeLoss" xlink:to="loc_us-gaapCurrentIncomeTaxExpenseBenefit" xlink:type="arc" weight="-1" />
    </link:calculationLink>
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/StatementsOfOperationsAndComprehensiveLossParenthetical" xlink:title="00000005 - Statement - Consolidated Statements of Operations and Comprehensive Loss (Parenthetical)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/StatementsOfCashFlows" xlink:title="00000006 - Statement - Consolidated Statements of Cash Flows">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaapNetIncomeLoss" />
      <link:calculationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapNetIncomeLoss" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_NoncashFinancingRelatedCharges" xlink:label="loc_avxlNoncashFinancingRelatedCharges" />
      <link:calculationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_avxlNoncashFinancingRelatedCharges" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaapShareBasedCompensation" />
      <link:calculationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapShareBasedCompensation" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInIncomeTaxesReceivable" xlink:label="loc_us-gaapIncreaseDecreaseInIncomeTaxesReceivable" />
      <link:calculationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapIncreaseDecreaseInIncomeTaxesReceivable" xlink:type="arc" weight="-1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInPrepaidExpense" xlink:label="loc_us-gaapIncreaseDecreaseInPrepaidExpense" />
      <link:calculationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapIncreaseDecreaseInPrepaidExpense" xlink:type="arc" weight="-1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInAccountsPayable" xlink:label="loc_us-gaapIncreaseDecreaseInAccountsPayable" />
      <link:calculationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapIncreaseDecreaseInAccountsPayable" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilities" xlink:label="loc_us-gaapIncreaseDecreaseInAccruedLiabilities" />
      <link:calculationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapIncreaseDecreaseInAccruedLiabilities" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DeferredGrantIncome" xlink:label="loc_avxlDeferredGrantIncome" />
      <link:calculationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_avxlDeferredGrantIncome" xlink:type="arc" weight="-1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock" xlink:label="loc_us-gaapProceedsFromIssuanceOfCommonStock" />
      <link:calculationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapProceedsFromIssuanceOfCommonStock" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PaymentsOfStockIssuanceCosts" xlink:label="loc_us-gaapPaymentsOfStockIssuanceCosts" />
      <link:calculationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapPaymentsOfStockIssuanceCosts" xlink:type="arc" weight="-1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromWarrantExercises" xlink:label="loc_us-gaapProceedsFromWarrantExercises" />
      <link:calculationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapProceedsFromWarrantExercises" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromStockOptionsExercised" xlink:label="loc_us-gaapProceedsFromStockOptionsExercised" />
      <link:calculationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapProceedsFromStockOptionsExercised" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:label="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" />
      <link:calculationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:to="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:type="arc" weight="1" />
      <link:calculationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:to="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:type="arc" weight="1" />
    </link:calculationLink>
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/StatementsOfChangesInStockholdersEquity" xlink:title="00000007 - Statement - Consolidated Statements of Changes in Stockholders&apos; Equity" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/BusinessDescriptionAndBasisOfPresentation" xlink:title="00000008 - Disclosure - Business Description and Basis of Presentation" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/SummaryOfSignificantAccountingPolicies" xlink:title="00000009 - Disclosure - Summary of Significant Accounting Policies" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/AccruedLiabilities" xlink:title="00000010 - Disclosure - Accrued Liabilities" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/OtherIncome" xlink:title="00000011 - Disclosure - Other Income" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/EquityOfferings" xlink:title="00000012 - Disclosure - Equity Offerings" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingencies" xlink:title="00000013 - Disclosure - Commitments and Contingencies" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxes" xlink:title="00000014 - Disclosure - Income Taxes" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/SubsequentEvents" xlink:title="00000015 - Disclosure - Subsequent Events" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:title="00000016 - Disclosure - Summary of Significant Accounting Policies (Policies)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/AccruedLiabilitiesTables" xlink:title="00000017 - Disclosure - Accrued Liabilities (Tables)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesTables" xlink:title="00000018 - Disclosure - Commitments and Contingencies (Tables)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxesTables" xlink:title="00000019 - Disclosure - Income Taxes (Tables)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/SummaryOfSignificantAccountingPoliciesDetailsNarrative" xlink:title="00000020 - Disclosure - Summary of Significant Accounting Policies (Details Narrative)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/AccruedLiabilitiesDetails" xlink:title="00000021 - Disclosure - Accrued Liabilities (Details)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="loc_us-gaapAccruedLiabilitiesCurrent" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_AccruedClinicalSiteAndPatientVisitsCosts" xlink:label="loc_avxlAccruedClinicalSiteAndPatientVisitsCosts" />
      <link:calculationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAccruedLiabilitiesCurrent" xlink:to="loc_avxlAccruedClinicalSiteAndPatientVisitsCosts" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccruedBonusesCurrent" xlink:label="loc_us-gaapAccruedBonusesCurrent" />
      <link:calculationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAccruedLiabilitiesCurrent" xlink:to="loc_us-gaapAccruedBonusesCurrent" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_FixedContractAccruals" xlink:label="loc_avxlFixedContractAccruals" />
      <link:calculationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAccruedLiabilitiesCurrent" xlink:to="loc_avxlFixedContractAccruals" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_MilestoneBasedContractAccruals" xlink:label="loc_avxlMilestoneBasedContractAccruals" />
      <link:calculationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAccruedLiabilitiesCurrent" xlink:to="loc_avxlMilestoneBasedContractAccruals" xlink:type="arc" weight="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherAccruedLiabilitiesCurrent" xlink:label="loc_us-gaapOtherAccruedLiabilitiesCurrent" />
      <link:calculationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAccruedLiabilitiesCurrent" xlink:to="loc_us-gaapOtherAccruedLiabilitiesCurrent" xlink:type="arc" weight="1" />
    </link:calculationLink>
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/OtherIncomeDetailsNarrative" xlink:title="00000022 - Disclosure - Other Income (Details Narrative)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/EquityOfferingsDetailsNarrative" xlink:title="00000023 - Disclosure - Equity Offerings (Details Narrative)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails" xlink:title="00000024 - Disclosure - Commitments and Contingencies (Details)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails1" xlink:title="00000025 - Disclosure - Commitments and Contingencies (Details 1)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails2" xlink:title="00000026 - Disclosure - Commitments and Contingencies (Details 2)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails3" xlink:title="00000027 - Disclosure - Commitments and Contingencies (Details 3)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails4" xlink:title="00000028 - Disclosure - Commitments and Contingencies (Details 4)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails5" xlink:title="00000029 - Disclosure - Commitments and Contingencies (Details 5)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails6" xlink:title="00000030 - Disclosure - Commitments and Contingencies (Details 6)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative" xlink:title="00000031 - Disclosure - Commitments and Contingencies (Details Narrative)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxesDetails" xlink:title="00000032 - Disclosure - Income Taxes (Details)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxesDetails1" xlink:title="00000033 - Disclosure - Income Taxes (Details 1)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxesDetails2" xlink:title="00000034 - Disclosure - Income Taxes (Details 2)" />
    <link:calculationLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxesDetailsNarrative" xlink:title="00000035 - Disclosure - Income Taxes (Details Narrative)" />
</link:linkbase>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.DEF
<SEQUENCE>14
<FILENAME>avxl-20230930_def.xml
<DESCRIPTION>XBRL DEFINITION FILE
<TEXT>
<XBRL>
<?xml version="1.0" encoding="US-ASCII" standalone="no"?>
    <!-- Field: Doc-Info; Name: Generator; Value: GoXBRL; Version: 5.20c -->
    <!-- Field: Doc-Info; Name: VendorURI; Value: https://www.novaworks.com -->
    <!-- Field: Doc-Info; Name: Status; Value: 0x00000000 -->
<link:linkbase xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:xbrli="http://www.xbrl.org/2003/instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
    <link:roleRef roleURI="http://anavex.com/role/Cover" xlink:href="avxl-20230930.xsd#Cover" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/BalanceSheets" xlink:href="avxl-20230930.xsd#BalanceSheets" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/BalanceSheetsParenthetical" xlink:href="avxl-20230930.xsd#BalanceSheetsParenthetical" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss" xlink:href="avxl-20230930.xsd#StatementsOfOperationsAndComprehensiveLoss" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/StatementsOfOperationsAndComprehensiveLossParenthetical" xlink:href="avxl-20230930.xsd#StatementsOfOperationsAndComprehensiveLossParenthetical" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/StatementsOfCashFlows" xlink:href="avxl-20230930.xsd#StatementsOfCashFlows" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/StatementsOfChangesInStockholdersEquity" xlink:href="avxl-20230930.xsd#StatementsOfChangesInStockholdersEquity" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/BusinessDescriptionAndBasisOfPresentation" xlink:href="avxl-20230930.xsd#BusinessDescriptionAndBasisOfPresentation" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/SummaryOfSignificantAccountingPolicies" xlink:href="avxl-20230930.xsd#SummaryOfSignificantAccountingPolicies" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/AccruedLiabilities" xlink:href="avxl-20230930.xsd#AccruedLiabilities" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/OtherIncome" xlink:href="avxl-20230930.xsd#OtherIncome" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/EquityOfferings" xlink:href="avxl-20230930.xsd#EquityOfferings" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingencies" xlink:href="avxl-20230930.xsd#CommitmentsAndContingencies" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxes" xlink:href="avxl-20230930.xsd#IncomeTaxes" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/SubsequentEvents" xlink:href="avxl-20230930.xsd#SubsequentEvents" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:href="avxl-20230930.xsd#SummaryOfSignificantAccountingPoliciesPolicies" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/AccruedLiabilitiesTables" xlink:href="avxl-20230930.xsd#AccruedLiabilitiesTables" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesTables" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesTables" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxesTables" xlink:href="avxl-20230930.xsd#IncomeTaxesTables" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/SummaryOfSignificantAccountingPoliciesDetailsNarrative" xlink:href="avxl-20230930.xsd#SummaryOfSignificantAccountingPoliciesDetailsNarrative" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/AccruedLiabilitiesDetails" xlink:href="avxl-20230930.xsd#AccruedLiabilitiesDetails" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/OtherIncomeDetailsNarrative" xlink:href="avxl-20230930.xsd#OtherIncomeDetailsNarrative" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/EquityOfferingsDetailsNarrative" xlink:href="avxl-20230930.xsd#EquityOfferingsDetailsNarrative" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails1" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails1" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails2" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails2" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails3" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails3" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails4" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails4" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails5" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails5" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails6" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails6" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetailsNarrative" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxesDetails" xlink:href="avxl-20230930.xsd#IncomeTaxesDetails" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxesDetails1" xlink:href="avxl-20230930.xsd#IncomeTaxesDetails1" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxesDetails2" xlink:href="avxl-20230930.xsd#IncomeTaxesDetails2" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxesDetailsNarrative" xlink:href="avxl-20230930.xsd#IncomeTaxesDetailsNarrative" xlink:type="simple" />
    <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#hypercube-dimension" arcroleURI="http://xbrl.org/int/dim/arcrole/hypercube-dimension" />
    <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-domain" arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-domain" />
    <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#domain-member" arcroleURI="http://xbrl.org/int/dim/arcrole/domain-member" />
    <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#all" arcroleURI="http://xbrl.org/int/dim/arcrole/all" />
    <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#notAll" arcroleURI="http://xbrl.org/int/dim/arcrole/notAll" />
    <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-default" arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-default" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/Cover" xlink:title="00000001 - Document - Cover" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/BalanceSheets" xlink:title="00000002 - Statement - Consolidated Balance Sheets" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/BalanceSheetsParenthetical" xlink:title="00000003 - Statement - Consolidated Balance Sheets (Parenthetical)" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss" xlink:title="00000004 - Statement - Consolidated Statements of Operations and Comprehensive Loss" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/StatementsOfOperationsAndComprehensiveLossParenthetical" xlink:title="00000005 - Statement - Consolidated Statements of Operations and Comprehensive Loss (Parenthetical)" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/StatementsOfCashFlows" xlink:title="00000006 - Statement - Consolidated Statements of Cash Flows" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/StatementsOfChangesInStockholdersEquity" xlink:title="00000007 - Statement - Consolidated Statements of Changes in Stockholders&apos; Equity">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStatementTable" xlink:type="arc" order="10" xbrldt:closed="true" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaapStatementEquityComponentsAxis" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaapStatementTable" xlink:to="loc_us-gaapStatementEquityComponentsAxis" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaapEquityComponentDomain" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaapStatementEquityComponentsAxis" xlink:to="loc_us-gaapEquityComponentDomain" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaapEquityComponentDomain_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_us-gaapStatementEquityComponentsAxis" xlink:to="loc_us-gaapEquityComponentDomain_10" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaapCommonStockMember_0" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapEquityComponentDomain" xlink:to="loc_us-gaapCommonStockMember_0" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="loc_us-gaapAdditionalPaidInCapitalMember_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapEquityComponentDomain" xlink:to="loc_us-gaapAdditionalPaidInCapitalMember_10" xlink:type="arc" order="11" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RetainedEarningsMember" xlink:label="loc_us-gaapRetainedEarningsMember_20" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapEquityComponentDomain" xlink:to="loc_us-gaapRetainedEarningsMember_20" xlink:type="arc" order="21" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaapStockholdersEquity_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStockholdersEquity_50" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharesOutstanding" xlink:label="loc_us-gaapSharesOutstanding_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapSharesOutstanding_50" xlink:type="arc" order="2" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares" xlink:label="loc_avxlSharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares_50" xlink:type="arc" order="3" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares" xlink:label="loc_avxlSharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares_50" xlink:type="arc" order="4" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockRepurchasedDuringPeriodValue" xlink:label="loc_us-gaapStockRepurchasedDuringPeriodValue_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStockRepurchasedDuringPeriodValue_50" xlink:type="arc" order="5" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockRepurchasedDuringPeriodShares" xlink:label="loc_us-gaapStockRepurchasedDuringPeriodShares_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStockRepurchasedDuringPeriodShares_50" xlink:type="arc" order="6" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CommitmentShares" xlink:label="loc_avxlCommitmentShares_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlCommitmentShares_50" xlink:type="arc" order="7" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CommitmentSharesShares" xlink:label="loc_avxlCommitmentSharesShares_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlCommitmentSharesShares_50" xlink:type="arc" order="8" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedUnderSalesAgreement" xlink:label="loc_avxlSharesIssuedUnderSalesAgreement_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedUnderSalesAgreement_50" xlink:type="arc" order="9" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedUnderSalesAgreementShares" xlink:label="loc_avxlSharesIssuedUnderSalesAgreementShares_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedUnderSalesAgreementShares_50" xlink:type="arc" order="10" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_LessSalesAgreementShareIssueCosts" xlink:label="loc_avxlLessSalesAgreementShareIssueCosts_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlLessSalesAgreementShareIssueCosts_50" xlink:type="arc" order="11" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPursuantToRegisteredDirectOffering" xlink:label="loc_avxlSharesIssuedPursuantToRegisteredDirectOffering_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedPursuantToRegisteredDirectOffering_50" xlink:type="arc" order="12" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPursuantToRegisteredDirectOfferingShares" xlink:label="loc_avxlSharesIssuedPursuantToRegisteredDirectOfferingShares_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedPursuantToRegisteredDirectOfferingShares_50" xlink:type="arc" order="13" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_LessRegisteredDirectOfferingShareIssueCosts" xlink:label="loc_avxlLessRegisteredDirectOfferingShareIssueCosts_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlLessRegisteredDirectOfferingShareIssueCosts_50" xlink:type="arc" order="14" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPursuantToExerciseOfStockOptions" xlink:label="loc_avxlSharesIssuedPursuantToExerciseOfStockOptions_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedPursuantToExerciseOfStockOptions_50" xlink:type="arc" order="15" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPursuantToExerciseOfStockOptionsShares" xlink:label="loc_avxlSharesIssuedPursuantToExerciseOfStockOptionsShares_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedPursuantToExerciseOfStockOptionsShares_50" xlink:type="arc" order="16" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPusuantToExerciseOfWarrants" xlink:label="loc_avxlSharesIssuedPusuantToExerciseOfWarrants_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedPusuantToExerciseOfWarrants_50" xlink:type="arc" order="17" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPusuantToExerciseOfWarrantsShares" xlink:label="loc_avxlSharesIssuedPusuantToExerciseOfWarrantsShares_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedPusuantToExerciseOfWarrantsShares_50" xlink:type="arc" order="18" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:label="loc_us-gaapAdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapAdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_50" xlink:type="arc" order="19" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaapNetIncomeLoss_50" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapNetIncomeLoss_50" xlink:type="arc" order="20" />
    </link:definitionLink>
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/BusinessDescriptionAndBasisOfPresentation" xlink:title="00000008 - Disclosure - Business Description and Basis of Presentation" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/SummaryOfSignificantAccountingPolicies" xlink:title="00000009 - Disclosure - Summary of Significant Accounting Policies" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/AccruedLiabilities" xlink:title="00000010 - Disclosure - Accrued Liabilities" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/OtherIncome" xlink:title="00000011 - Disclosure - Other Income" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/EquityOfferings" xlink:title="00000012 - Disclosure - Equity Offerings" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingencies" xlink:title="00000013 - Disclosure - Commitments and Contingencies" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxes" xlink:title="00000014 - Disclosure - Income Taxes" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/SubsequentEvents" xlink:title="00000015 - Disclosure - Subsequent Events" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:title="00000016 - Disclosure - Summary of Significant Accounting Policies (Policies)" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/AccruedLiabilitiesTables" xlink:title="00000017 - Disclosure - Accrued Liabilities (Tables)" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesTables" xlink:title="00000018 - Disclosure - Commitments and Contingencies (Tables)" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxesTables" xlink:title="00000019 - Disclosure - Income Taxes (Tables)" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/SummaryOfSignificantAccountingPoliciesDetailsNarrative" xlink:title="00000020 - Disclosure - Summary of Significant Accounting Policies (Details Narrative)" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/AccruedLiabilitiesDetails" xlink:title="00000021 - Disclosure - Accrued Liabilities (Details)" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/OtherIncomeDetailsNarrative" xlink:title="00000022 - Disclosure - Other Income (Details Narrative)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems" xlink:label="loc_us-gaapDefinedBenefitPlanDisclosureLineItems" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable" xlink:label="loc_us-gaapScheduleOfDefinedBenefitPlansDisclosuresTable" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_us-gaapDefinedBenefitPlanDisclosureLineItems" xlink:to="loc_us-gaapScheduleOfDefinedBenefitPlansDisclosuresTable" xlink:type="arc" order="10" xbrldt:closed="true" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="loc_us-gaapRelatedPartyTransactionsByRelatedPartyAxis" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaapScheduleOfDefinedBenefitPlansDisclosuresTable" xlink:to="loc_us-gaapRelatedPartyTransactionsByRelatedPartyAxis" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_us-gaapRelatedPartyDomain" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaapRelatedPartyTransactionsByRelatedPartyAxis" xlink:to="loc_us-gaapRelatedPartyDomain" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_us-gaapRelatedPartyDomain_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_us-gaapRelatedPartyTransactionsByRelatedPartyAxis" xlink:to="loc_us-gaapRelatedPartyDomain_10" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_MichaelJFoxFoundationMember" xlink:label="loc_avxlMichaelJFoxFoundationMember_30" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapRelatedPartyDomain" xlink:to="loc_avxlMichaelJFoxFoundationMember_30" xlink:type="arc" order="31" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2023/elts/srt-2023.xsd#srt_CurrencyAxis" xlink:label="loc_srtCurrencyAxis" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaapScheduleOfDefinedBenefitPlansDisclosuresTable" xlink:to="loc_srtCurrencyAxis" xlink:type="arc" order="2" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/currency/2023/currency-2023.xsd#currency_AllCurrenciesDomain" xlink:label="loc_currencyAllCurrenciesDomain" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srtCurrencyAxis" xlink:to="loc_currencyAllCurrenciesDomain" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/currency/2023/currency-2023.xsd#currency_AllCurrenciesDomain" xlink:label="loc_currencyAllCurrenciesDomain_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_srtCurrencyAxis" xlink:to="loc_currencyAllCurrenciesDomain_10" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/currency/2023/currency-2023.xsd#currency_AUD" xlink:label="loc_currencyAUD_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_currencyAllCurrenciesDomain" xlink:to="loc_currencyAUD_40" xlink:type="arc" order="41" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_GrantIncome" xlink:label="loc_avxlGrantIncome_120" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapDefinedBenefitPlanDisclosureLineItems" xlink:to="loc_avxlGrantIncome_120" xlink:type="arc" order="0" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned" xlink:label="loc_us-gaapResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_120" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapDefinedBenefitPlanDisclosureLineItems" xlink:to="loc_us-gaapResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_120" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_NonOperatingIncomeFromGrant" xlink:label="loc_avxlNonOperatingIncomeFromGrant_120" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapDefinedBenefitPlanDisclosureLineItems" xlink:to="loc_avxlNonOperatingIncomeFromGrant_120" xlink:type="arc" order="2" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DeferredGrantIncome1" xlink:label="loc_avxlDeferredGrantIncome1_120" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapDefinedBenefitPlanDisclosureLineItems" xlink:to="loc_avxlDeferredGrantIncome1_120" xlink:type="arc" order="3" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherReceivables" xlink:label="loc_us-gaapOtherReceivables_120" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapDefinedBenefitPlanDisclosureLineItems" xlink:to="loc_us-gaapOtherReceivables_120" xlink:type="arc" order="4" />
    </link:definitionLink>
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/EquityOfferingsDetailsNarrative" xlink:title="00000023 - Disclosure - Equity Offerings (Details Narrative)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStatementTable" xlink:type="arc" order="10" xbrldt:closed="true" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_TypeOfArrangementAxis" xlink:label="loc_us-gaapTypeOfArrangementAxis" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaapStatementTable" xlink:to="loc_us-gaapTypeOfArrangementAxis" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember" xlink:label="loc_us-gaapArrangementsAndNonarrangementTransactionsMember" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaapTypeOfArrangementAxis" xlink:to="loc_us-gaapArrangementsAndNonarrangementTransactionsMember" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember" xlink:label="loc_us-gaapArrangementsAndNonarrangementTransactionsMember_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_us-gaapTypeOfArrangementAxis" xlink:to="loc_us-gaapArrangementsAndNonarrangementTransactionsMember_10" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SecuritiesPurchaseAgreementMember" xlink:label="loc_avxlSecuritiesPurchaseAgreementMember_0" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapArrangementsAndNonarrangementTransactionsMember" xlink:to="loc_avxlSecuritiesPurchaseAgreementMember_0" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_EquityOfferingSalesAgreementMember" xlink:label="loc_avxlEquityOfferingSalesAgreementMember_20" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapArrangementsAndNonarrangementTransactionsMember" xlink:to="loc_avxlEquityOfferingSalesAgreementMember_20" xlink:type="arc" order="21" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PurchaseAgreement2023Member" xlink:label="loc_avxlPurchaseAgreement2023Member_70" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapArrangementsAndNonarrangementTransactionsMember" xlink:to="loc_avxlPurchaseAgreement2023Member_70" xlink:type="arc" order="71" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PurchaseAgreement2019Member" xlink:label="loc_avxlPurchaseAgreement2019Member_160" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapArrangementsAndNonarrangementTransactionsMember" xlink:to="loc_avxlPurchaseAgreement2019Member_160" xlink:type="arc" order="161" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_LegalEntityAxis" xlink:label="loc_deiLegalEntityAxis" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaapStatementTable" xlink:to="loc_deiLegalEntityAxis" xlink:type="arc" order="2" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityDomain" xlink:label="loc_deiEntityDomain" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_deiLegalEntityAxis" xlink:to="loc_deiEntityDomain" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityDomain" xlink:label="loc_deiEntityDomain_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_deiLegalEntityAxis" xlink:to="loc_deiEntityDomain_10" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_LincolnParkCapitalFundLLCMember" xlink:label="loc_avxlLincolnParkCapitalFundLLCMember_70" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_deiEntityDomain" xlink:to="loc_avxlLincolnParkCapitalFundLLCMember_70" xlink:type="arc" order="72" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementClassOfStockAxis" xlink:label="loc_us-gaapStatementClassOfStockAxis" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaapStatementTable" xlink:to="loc_us-gaapStatementClassOfStockAxis" xlink:type="arc" order="3" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ClassOfStockDomain" xlink:label="loc_us-gaapClassOfStockDomain" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaapStatementClassOfStockAxis" xlink:to="loc_us-gaapClassOfStockDomain" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ClassOfStockDomain" xlink:label="loc_us-gaapClassOfStockDomain_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_us-gaapStatementClassOfStockAxis" xlink:to="loc_us-gaapClassOfStockDomain_10" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CommonStockIncludingCommitmentSharesMember" xlink:label="loc_avxlCommonStockIncludingCommitmentSharesMember_80" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapClassOfStockDomain" xlink:to="loc_avxlCommonStockIncludingCommitmentSharesMember_80" xlink:type="arc" order="83" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CommonStockExcludingCommitmentSharesMember" xlink:label="loc_avxlCommonStockExcludingCommitmentSharesMember_100" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapClassOfStockDomain" xlink:to="loc_avxlCommonStockExcludingCommitmentSharesMember_100" xlink:type="arc" order="103" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CommitmentSharesMember" xlink:label="loc_avxlCommitmentSharesMember_140" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapClassOfStockDomain" xlink:to="loc_avxlCommitmentSharesMember_140" xlink:type="arc" order="143" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaapCommonStockMember_190" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapClassOfStockDomain" xlink:to="loc_us-gaapCommonStockMember_190" xlink:type="arc" order="193" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction" xlink:label="loc_us-gaapSaleOfStockNumberOfSharesIssuedInTransaction_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapSaleOfStockNumberOfSharesIssuedInTransaction_240" xlink:type="arc" order="0" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SaleOfStockPricePerShare" xlink:label="loc_us-gaapSaleOfStockPricePerShare_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapSaleOfStockPricePerShare_240" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SaleOfStockConsiderationReceivedOnTransaction" xlink:label="loc_us-gaapSaleOfStockConsiderationReceivedOnTransaction_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapSaleOfStockConsiderationReceivedOnTransaction_240" xlink:type="arc" order="2" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromIssuanceInitialPublicOffering" xlink:label="loc_us-gaapProceedsFromIssuanceInitialPublicOffering_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapProceedsFromIssuanceInitialPublicOffering_240" xlink:type="arc" order="3" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PercentageOfGrossProceedsFromSales" xlink:label="loc_avxlPercentageOfGrossProceedsFromSales_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlPercentageOfGrossProceedsFromSales_240" xlink:type="arc" order="4" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SaleOfStockConsiderationReceivedPerTransaction" xlink:label="loc_us-gaapSaleOfStockConsiderationReceivedPerTransaction_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapSaleOfStockConsiderationReceivedPerTransaction_240" xlink:type="arc" order="5" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SoldForGrossProceedsAmount" xlink:label="loc_avxlSoldForGrossProceedsAmount_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSoldForGrossProceedsAmount_240" xlink:type="arc" order="6" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SalesOfAgreementAmount" xlink:label="loc_avxlSalesOfAgreementAmount_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSalesOfAgreementAmount_240" xlink:type="arc" order="7" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ValueOfSharesObligatedToPurchase" xlink:label="loc_avxlValueOfSharesObligatedToPurchase_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlValueOfSharesObligatedToPurchase_240" xlink:type="arc" order="8" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:label="loc_us-gaapStockIssuedDuringPeriodSharesNewIssues_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStockIssuedDuringPeriodSharesNewIssues_240" xlink:type="arc" order="9" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_NumberOfSharesObligatedToPurchaseProrataBasic" xlink:label="loc_avxlNumberOfSharesObligatedToPurchaseProrataBasic_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlNumberOfSharesObligatedToPurchaseProrataBasic_240" xlink:type="arc" order="10" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromIssuanceOrSaleOfEquity" xlink:label="loc_us-gaapProceedsFromIssuanceOrSaleOfEquity_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapProceedsFromIssuanceOrSaleOfEquity_240" xlink:type="arc" order="11" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_FairValueOfInitialCommitment" xlink:label="loc_avxlFairValueOfInitialCommitment_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlFairValueOfInitialCommitment_240" xlink:type="arc" order="12" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_IncurredExpenses" xlink:label="loc_avxlIncurredExpenses_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlIncurredExpenses_240" xlink:type="arc" order="13" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues" xlink:label="loc_us-gaapStockIssuedDuringPeriodValueNewIssues_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStockIssuedDuringPeriodValueNewIssues_240" xlink:type="arc" order="14" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockIssuedDuringPeriodValueOther" xlink:label="loc_us-gaapStockIssuedDuringPeriodValueOther_240" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStockIssuedDuringPeriodValueOther_240" xlink:type="arc" order="15" />
    </link:definitionLink>
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails" xlink:title="00000024 - Disclosure - Commitments and Contingencies (Details)" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails1" xlink:title="00000025 - Disclosure - Commitments and Contingencies (Details 1)" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails2" xlink:title="00000026 - Disclosure - Commitments and Contingencies (Details 2)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaapScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:type="arc" order="10" xbrldt:closed="true" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaapAwardTypeAxis" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaapScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:to="loc_us-gaapAwardTypeAxis" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaapAwardTypeAxis" xlink:to="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_us-gaapAwardTypeAxis" xlink:to="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_10" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PurchaseWarrants1Member" xlink:label="loc_avxlPurchaseWarrants1Member_0" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:to="loc_avxlPurchaseWarrants1Member_0" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PurchaseWarrants2Member" xlink:label="loc_avxlPurchaseWarrants2Member_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:to="loc_avxlPurchaseWarrants2Member_10" xlink:type="arc" order="11" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_40" xlink:type="arc" order="0" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_40" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_WarrantsAndRightsOutstandingMaturityDate" xlink:label="loc_us-gaapWarrantsAndRightsOutstandingMaturityDate_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapWarrantsAndRightsOutstandingMaturityDate_40" xlink:type="arc" order="2" />
    </link:definitionLink>
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails3" xlink:title="00000027 - Disclosure - Commitments and Contingencies (Details 3)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OffsettingAssetsLineItems" xlink:label="loc_us-gaapOffsettingAssetsLineItems" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OffsettingAssetsTable" xlink:label="loc_us-gaapOffsettingAssetsTable" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapOffsettingAssetsTable" xlink:type="arc" order="10" xbrldt:closed="true" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_us-gaapDerivativeInstrumentRiskAxis" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaapOffsettingAssetsTable" xlink:to="loc_us-gaapDerivativeInstrumentRiskAxis" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaapDerivativeContractTypeDomain" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaapDerivativeInstrumentRiskAxis" xlink:to="loc_us-gaapDerivativeContractTypeDomain" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaapDerivativeContractTypeDomain_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_us-gaapDerivativeInstrumentRiskAxis" xlink:to="loc_us-gaapDerivativeContractTypeDomain_10" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockOptionMember" xlink:label="loc_us-gaapStockOptionMember_0" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapDerivativeContractTypeDomain" xlink:to="loc_us-gaapStockOptionMember_0" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_60" xlink:type="arc" order="0" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_60" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_60" xlink:type="arc" order="2" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_60" xlink:type="arc" order="3" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_60" xlink:type="arc" order="4" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_60" xlink:type="arc" order="5" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_60" xlink:type="arc" order="6" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_60" xlink:type="arc" order="7" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_60" xlink:type="arc" order="8" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice" xlink:label="loc_avxlShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_avxlShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice_60" xlink:type="arc" order="9" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="loc_us-gaapStockIssuedDuringPeriodSharesStockOptionsExercised_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapStockIssuedDuringPeriodSharesStockOptionsExercised_60" xlink:type="arc" order="10" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_60" xlink:type="arc" order="11" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice" xlink:label="loc_avxlShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_avxlShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice_60" xlink:type="arc" order="12" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_60" xlink:type="arc" order="13" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_60" xlink:type="arc" order="18" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_60" xlink:type="arc" order="19" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue_60" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_60" xlink:type="arc" order="21" />
    </link:definitionLink>
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails4" xlink:title="00000028 - Disclosure - Commitments and Contingencies (Details 4)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OffsettingAssetsLineItems" xlink:label="loc_us-gaapOffsettingAssetsLineItems" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OffsettingAssetsTable" xlink:label="loc_us-gaapOffsettingAssetsTable" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapOffsettingAssetsTable" xlink:type="arc" order="10" xbrldt:closed="true" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_us-gaapDerivativeInstrumentRiskAxis" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaapOffsettingAssetsTable" xlink:to="loc_us-gaapDerivativeInstrumentRiskAxis" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaapDerivativeContractTypeDomain" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaapDerivativeInstrumentRiskAxis" xlink:to="loc_us-gaapDerivativeContractTypeDomain" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaapDerivativeContractTypeDomain_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_us-gaapDerivativeInstrumentRiskAxis" xlink:to="loc_us-gaapDerivativeContractTypeDomain_10" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockOptionMember" xlink:label="loc_us-gaapStockOptionMember_0" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapDerivativeContractTypeDomain" xlink:to="loc_us-gaapStockOptionMember_0" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis" xlink:label="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaapOffsettingAssetsTable" xlink:to="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis" xlink:type="arc" order="2" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:label="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis" xlink:to="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:label="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis" xlink:to="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_10" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionPrice1Member" xlink:label="loc_avxlOptionPrice1Member_0" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:to="loc_avxlOptionPrice1Member_0" xlink:type="arc" order="2" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionPrice2Member" xlink:label="loc_avxlOptionPrice2Member_20" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:to="loc_avxlOptionPrice2Member_20" xlink:type="arc" order="22" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionPrice3Member" xlink:label="loc_avxlOptionPrice3Member_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:to="loc_avxlOptionPrice3Member_40" xlink:type="arc" order="42" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionPrice4Member" xlink:label="loc_avxlOptionPrice4Member_60" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:to="loc_avxlOptionPrice4Member_60" xlink:type="arc" order="62" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionPrice5Member" xlink:label="loc_avxlOptionPrice5Member_80" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:to="loc_avxlOptionPrice5Member_80" xlink:type="arc" order="82" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit" xlink:label="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_130" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_130" xlink:type="arc" order="0" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit" xlink:label="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_130" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_130" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_130" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_130" xlink:type="arc" order="2" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_130" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_130" xlink:type="arc" order="3" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_130" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_130" xlink:type="arc" order="4" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_130" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_130" xlink:type="arc" order="5" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_130" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_130" xlink:type="arc" order="6" />
    </link:definitionLink>
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails5" xlink:title="00000029 - Disclosure - Commitments and Contingencies (Details 5)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LossContingenciesLineItems" xlink:label="loc_us-gaapLossContingenciesLineItems" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LossContingenciesTable" xlink:label="loc_us-gaapLossContingenciesTable" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_us-gaapLossContingenciesLineItems" xlink:to="loc_us-gaapLossContingenciesTable" xlink:type="arc" order="10" xbrldt:closed="true" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaapIncomeStatementLocationAxis" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaapLossContingenciesTable" xlink:to="loc_us-gaapIncomeStatementLocationAxis" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaapIncomeStatementLocationDomain" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaapIncomeStatementLocationAxis" xlink:to="loc_us-gaapIncomeStatementLocationDomain" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaapIncomeStatementLocationDomain_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_us-gaapIncomeStatementLocationAxis" xlink:to="loc_us-gaapIncomeStatementLocationDomain_10" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_GeneralAndAdministrativeExpenseMember" xlink:label="loc_us-gaapGeneralAndAdministrativeExpenseMember_0" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapIncomeStatementLocationDomain" xlink:to="loc_us-gaapGeneralAndAdministrativeExpenseMember_0" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ResearchAndDevelopmentExpenseMember" xlink:label="loc_us-gaapResearchAndDevelopmentExpenseMember_30" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapIncomeStatementLocationDomain" xlink:to="loc_us-gaapResearchAndDevelopmentExpenseMember_30" xlink:type="arc" order="31" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaapShareBasedCompensation_100" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapLossContingenciesLineItems" xlink:to="loc_us-gaapShareBasedCompensation_100" xlink:type="arc" order="0" />
    </link:definitionLink>
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails6" xlink:title="00000030 - Disclosure - Commitments and Contingencies (Details 6)" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative" xlink:title="00000031 - Disclosure - Commitments and Contingencies (Details Narrative)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaapScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:type="arc" order="10" xbrldt:closed="true" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PlanNameAxis" xlink:label="loc_us-gaapPlanNameAxis" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaapScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:to="loc_us-gaapPlanNameAxis" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PlanNameDomain" xlink:label="loc_us-gaapPlanNameDomain" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaapPlanNameAxis" xlink:to="loc_us-gaapPlanNameDomain" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PlanNameDomain" xlink:label="loc_us-gaapPlanNameDomain_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_us-gaapPlanNameAxis" xlink:to="loc_us-gaapPlanNameDomain_10" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_StockOptionPlan2015Member" xlink:label="loc_avxlStockOptionPlan2015Member_20" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapPlanNameDomain" xlink:to="loc_avxlStockOptionPlan2015Member_20" xlink:type="arc" order="21" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_StockOptionPlan2019Member" xlink:label="loc_avxlStockOptionPlan2019Member_30" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapPlanNameDomain" xlink:to="loc_avxlStockOptionPlan2019Member_30" xlink:type="arc" order="31" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_StockOptionPlan2022Member" xlink:label="loc_avxlStockOptionPlan2022Member_40" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapPlanNameDomain" xlink:to="loc_avxlStockOptionPlan2022Member_40" xlink:type="arc" order="41" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1" xlink:label="loc_us-gaapOperatingLeaseWeightedAverageRemainingLeaseTerm1_110" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapOperatingLeaseWeightedAverageRemainingLeaseTerm1_110" xlink:type="arc" order="0" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ClassOfWarrantOrRightOutstanding" xlink:label="loc_us-gaapClassOfWarrantOrRightOutstanding_110" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapClassOfWarrantOrRightOutstanding_110" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_WarrantsOutstandingWeightedAverageExercise" xlink:label="loc_avxlWarrantsOutstandingWeightedAverageExercise_110" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_avxlWarrantsOutstandingWeightedAverageExercise_110" xlink:type="arc" order="2" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance" xlink:label="loc_us-gaapCommonStockCapitalSharesReservedForFutureIssuance_110" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapCommonStockCapitalSharesReservedForFutureIssuance_110" xlink:type="arc" order="3" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_110" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_110" xlink:type="arc" order="4" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod_110" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod_110" xlink:type="arc" order="5" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionIssued" xlink:label="loc_avxlOptionIssued_110" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_avxlOptionIssued_110" xlink:type="arc" order="6" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_110" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_110" xlink:type="arc" order="7" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_110" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_110" xlink:type="arc" order="8" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_110" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_110" xlink:type="arc" order="9" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2" xlink:label="loc_us-gaapSharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_110" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapSharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_110" xlink:type="arc" order="10" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AllocatedShareBasedCompensationExpense" xlink:label="loc_us-gaapAllocatedShareBasedCompensationExpense_110" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapAllocatedShareBasedCompensationExpense_110" xlink:type="arc" order="11" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions" xlink:label="loc_us-gaapEmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_110" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapEmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_110" xlink:type="arc" order="12" />
    </link:definitionLink>
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxesDetails" xlink:title="00000032 - Disclosure - Income Taxes (Details)" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxesDetails1" xlink:title="00000033 - Disclosure - Income Taxes (Details 1)" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxesDetails2" xlink:title="00000034 - Disclosure - Income Taxes (Details 2)" />
    <link:definitionLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxesDetailsNarrative" xlink:title="00000035 - Disclosure - Income Taxes (Details Narrative)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLossCarryforwardsLineItems" xlink:label="loc_us-gaapOperatingLossCarryforwardsLineItems" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLossCarryforwardsTable" xlink:label="loc_us-gaapOperatingLossCarryforwardsTable" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_us-gaapOperatingLossCarryforwardsTable" xlink:type="arc" order="10" xbrldt:closed="true" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxAuthorityAxis" xlink:label="loc_us-gaapIncomeTaxAuthorityAxis" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaapOperatingLossCarryforwardsTable" xlink:to="loc_us-gaapIncomeTaxAuthorityAxis" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxAuthorityDomain" xlink:label="loc_us-gaapIncomeTaxAuthorityDomain" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaapIncomeTaxAuthorityAxis" xlink:to="loc_us-gaapIncomeTaxAuthorityDomain" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxAuthorityDomain" xlink:label="loc_us-gaapIncomeTaxAuthorityDomain_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_us-gaapIncomeTaxAuthorityAxis" xlink:to="loc_us-gaapIncomeTaxAuthorityDomain_10" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_FederalMember" xlink:label="loc_avxlFederalMember_0" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapIncomeTaxAuthorityDomain" xlink:to="loc_avxlFederalMember_0" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StateAndLocalJurisdictionMember" xlink:label="loc_us-gaapStateAndLocalJurisdictionMember_30" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapIncomeTaxAuthorityDomain" xlink:to="loc_us-gaapStateAndLocalJurisdictionMember_30" xlink:type="arc" order="31" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ForeignCountryMember" xlink:label="loc_us-gaapForeignCountryMember_70" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapIncomeTaxAuthorityDomain" xlink:to="loc_us-gaapForeignCountryMember_70" xlink:type="arc" order="71" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2023/elts/srt-2023.xsd#srt_CurrencyAxis" xlink:label="loc_srtCurrencyAxis" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaapOperatingLossCarryforwardsTable" xlink:to="loc_srtCurrencyAxis" xlink:type="arc" order="2" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/currency/2023/currency-2023.xsd#currency_AllCurrenciesDomain" xlink:label="loc_currencyAllCurrenciesDomain" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srtCurrencyAxis" xlink:to="loc_currencyAllCurrenciesDomain" xlink:type="arc" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/currency/2023/currency-2023.xsd#currency_AllCurrenciesDomain" xlink:label="loc_currencyAllCurrenciesDomain_10" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_srtCurrencyAxis" xlink:to="loc_currencyAllCurrenciesDomain_10" xlink:type="arc" order="30" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/currency/2023/currency-2023.xsd#currency_AUD" xlink:label="loc_currencyAUD_80" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_currencyAllCurrenciesDomain" xlink:to="loc_currencyAUD_80" xlink:type="arc" order="82" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLossCarryforwards" xlink:label="loc_us-gaapOperatingLossCarryforwards_170" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_us-gaapOperatingLossCarryforwards_170" xlink:type="arc" order="0" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OperatingLossCarryforwardsDescription" xlink:label="loc_avxlOperatingLossCarryforwardsDescription_170" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_avxlOperatingLossCarryforwardsDescription_170" xlink:type="arc" order="1" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OperatingLossCarryForwardsExpirationYear" xlink:label="loc_avxlOperatingLossCarryForwardsExpirationYear_170" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_avxlOperatingLossCarryForwardsExpirationYear_170" xlink:type="arc" order="2" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment" xlink:label="loc_us-gaapIncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment_170" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_us-gaapIncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment_170" xlink:type="arc" order="3" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ResearchAndDevelopmentTaxCreditsYear" xlink:label="loc_avxlResearchAndDevelopmentTaxCreditsYear_170" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_avxlResearchAndDevelopmentTaxCreditsYear_170" xlink:type="arc" order="4" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsGross" xlink:label="loc_us-gaapDeferredTaxAssetsGross_170" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_us-gaapDeferredTaxAssetsGross_170" xlink:type="arc" order="5" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch" xlink:label="loc_us-gaapDeferredTaxAssetsTaxCreditCarryforwardsResearch_170" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_us-gaapDeferredTaxAssetsTaxCreditCarryforwardsResearch_170" xlink:type="arc" order="6" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount" xlink:label="loc_us-gaapValuationAllowanceDeferredTaxAssetChangeInAmount_170" />
      <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_us-gaapValuationAllowanceDeferredTaxAssetChangeInAmount_170" xlink:type="arc" order="7" />
    </link:definitionLink>
</link:linkbase>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.LAB
<SEQUENCE>15
<FILENAME>avxl-20230930_lab.xml
<DESCRIPTION>XBRL LABEL FILE
<TEXT>
<XBRL>
<?xml version="1.0" encoding="US-ASCII" standalone="no"?>
    <!-- Field: Doc-Info; Name: Generator; Value: GoXBRL; Version: 5.20c -->
    <!-- Field: Doc-Info; Name: VendorURI; Value: https://www.novaworks.com -->
    <!-- Field: Doc-Info; Name: Status; Value: 0x00000000 -->
<link:linkbase xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrli="http://www.xbrl.org/2003/instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
    <link:roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel" roleURI="http://www.xbrl.org/2009/role/negatedLabel" />
    <link:roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodEndLabel" roleURI="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" />
    <link:roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodStartLabel" roleURI="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" />
    <link:roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel" roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" />
    <link:roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedNetLabel" roleURI="http://www.xbrl.org/2009/role/negatedNetLabel" />
    <link:roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTerseLabel" roleURI="http://www.xbrl.org/2009/role/negatedTerseLabel" />
    <link:roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd#netLabel" roleURI="http://www.xbrl.org/2009/role/netLabel" />
    <link:labelLink xlink:type="extended" xlink:role="http://www.xbrl.org/2003/role/link">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="us-gaap_StatementEquityComponentsAxis" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementEquityComponentsAxis" xlink:to="us-gaap_StatementEquityComponentsAxis_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementEquityComponentsAxis_lbl" xml:lang="en-US">Equity Components [Axis]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockMember" xlink:label="us-gaap_CommonStockMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockMember" xlink:to="us-gaap_CommonStockMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonStockMember_lbl" xml:lang="en-US">Common Stock [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="us-gaap_AdditionalPaidInCapitalMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AdditionalPaidInCapitalMember" xlink:to="us-gaap_AdditionalPaidInCapitalMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AdditionalPaidInCapitalMember_lbl" xml:lang="en-US">Additional Paid-in Capital [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RetainedEarningsMember" xlink:label="us-gaap_RetainedEarningsMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_RetainedEarningsMember" xlink:to="us-gaap_RetainedEarningsMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_RetainedEarningsMember_lbl" xml:lang="en-US">Retained Earnings [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:to="us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_lbl" xml:lang="en-US">Related Party, Type [Axis]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_MichaelJFoxFoundationMember" xlink:label="avxl_MichaelJFoxFoundationMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_MichaelJFoxFoundationMember" xlink:to="avxl_MichaelJFoxFoundationMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_MichaelJFoxFoundationMember_lbl" xml:lang="en-US">Michael J Fox Foundation [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2023/elts/srt-2023.xsd#srt_CurrencyAxis" xlink:label="srt_CurrencyAxis" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="srt_CurrencyAxis" xlink:to="srt_CurrencyAxis_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="srt_CurrencyAxis_lbl" xml:lang="en-US">Currency [Axis]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/currency/2023/currency-2023.xsd#currency_AUD" xlink:label="currency_AUD" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="currency_AUD" xlink:to="currency_AUD_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="currency_AUD_lbl" xml:lang="en-US">Australia, Dollars</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_TypeOfArrangementAxis" xlink:label="us-gaap_TypeOfArrangementAxis" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_TypeOfArrangementAxis" xlink:to="us-gaap_TypeOfArrangementAxis_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_TypeOfArrangementAxis_lbl" xml:lang="en-US">Collaborative Arrangement and Arrangement Other than Collaborative [Axis]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SecuritiesPurchaseAgreementMember" xlink:label="avxl_SecuritiesPurchaseAgreementMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_SecuritiesPurchaseAgreementMember" xlink:to="avxl_SecuritiesPurchaseAgreementMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_SecuritiesPurchaseAgreementMember_lbl" xml:lang="en-US">Securities Purchase Agreement [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_EquityOfferingSalesAgreementMember" xlink:label="avxl_EquityOfferingSalesAgreementMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_EquityOfferingSalesAgreementMember" xlink:to="avxl_EquityOfferingSalesAgreementMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_EquityOfferingSalesAgreementMember_lbl" xml:lang="en-US">Equity Offering Sales Agreement [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PurchaseAgreement2023Member" xlink:label="avxl_PurchaseAgreement2023Member" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_PurchaseAgreement2023Member" xlink:to="avxl_PurchaseAgreement2023Member_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_PurchaseAgreement2023Member_lbl" xml:lang="en-US">Purchase Agreement 2023 [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_LegalEntityAxis" xlink:label="dei_LegalEntityAxis" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_LegalEntityAxis" xlink:to="dei_LegalEntityAxis_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_LegalEntityAxis_lbl" xml:lang="en-US">Legal Entity [Axis]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_LincolnParkCapitalFundLLCMember" xlink:label="avxl_LincolnParkCapitalFundLLCMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_LincolnParkCapitalFundLLCMember" xlink:to="avxl_LincolnParkCapitalFundLLCMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_LincolnParkCapitalFundLLCMember_lbl" xml:lang="en-US">Lincoln Park Capital Fund L L C [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementClassOfStockAxis" xlink:label="us-gaap_StatementClassOfStockAxis" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementClassOfStockAxis" xlink:to="us-gaap_StatementClassOfStockAxis_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementClassOfStockAxis_lbl" xml:lang="en-US">Class of Stock [Axis]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CommonStockIncludingCommitmentSharesMember" xlink:label="avxl_CommonStockIncludingCommitmentSharesMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_CommonStockIncludingCommitmentSharesMember" xlink:to="avxl_CommonStockIncludingCommitmentSharesMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_CommonStockIncludingCommitmentSharesMember_lbl" xml:lang="en-US">Common Stock Including Commitment Shares [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CommonStockExcludingCommitmentSharesMember" xlink:label="avxl_CommonStockExcludingCommitmentSharesMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_CommonStockExcludingCommitmentSharesMember" xlink:to="avxl_CommonStockExcludingCommitmentSharesMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_CommonStockExcludingCommitmentSharesMember_lbl" xml:lang="en-US">Common Stock Excluding Commitment Shares [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CommitmentSharesMember" xlink:label="avxl_CommitmentSharesMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_CommitmentSharesMember" xlink:to="avxl_CommitmentSharesMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_CommitmentSharesMember_lbl" xml:lang="en-US">Commitment Shares [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PurchaseAgreement2019Member" xlink:label="avxl_PurchaseAgreement2019Member" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_PurchaseAgreement2019Member" xlink:to="avxl_PurchaseAgreement2019Member_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_PurchaseAgreement2019Member_lbl" xml:lang="en-US">Purchase Agreement 2019 [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PlanNameAxis" xlink:label="us-gaap_PlanNameAxis" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PlanNameAxis" xlink:to="us-gaap_PlanNameAxis_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PlanNameAxis_lbl" xml:lang="en-US">Plan Name [Axis]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_StockOptionPlan2015Member" xlink:label="avxl_StockOptionPlan2015Member" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_StockOptionPlan2015Member" xlink:to="avxl_StockOptionPlan2015Member_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_StockOptionPlan2015Member_lbl" xml:lang="en-US">Stock Option Plan 2015 [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_StockOptionPlan2019Member" xlink:label="avxl_StockOptionPlan2019Member" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_StockOptionPlan2019Member" xlink:to="avxl_StockOptionPlan2019Member_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_StockOptionPlan2019Member_lbl" xml:lang="en-US">Stock Option Plan 2019 [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_StockOptionPlan2022Member" xlink:label="avxl_StockOptionPlan2022Member" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_StockOptionPlan2022Member" xlink:to="avxl_StockOptionPlan2022Member_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_StockOptionPlan2022Member_lbl" xml:lang="en-US">Stock Option Plan 2022 [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AwardTypeAxis" xlink:label="us-gaap_AwardTypeAxis" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AwardTypeAxis" xlink:to="us-gaap_AwardTypeAxis_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AwardTypeAxis_lbl" xml:lang="en-US">Award Type [Axis]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PurchaseWarrants1Member" xlink:label="avxl_PurchaseWarrants1Member" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_PurchaseWarrants1Member" xlink:to="avxl_PurchaseWarrants1Member_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_PurchaseWarrants1Member_lbl" xml:lang="en-US">Purchase Warrants 1 [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PurchaseWarrants2Member" xlink:label="avxl_PurchaseWarrants2Member" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_PurchaseWarrants2Member" xlink:to="avxl_PurchaseWarrants2Member_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_PurchaseWarrants2Member_lbl" xml:lang="en-US">Purchase Warrants 2 [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="us-gaap_DerivativeInstrumentRiskAxis" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DerivativeInstrumentRiskAxis" xlink:to="us-gaap_DerivativeInstrumentRiskAxis_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DerivativeInstrumentRiskAxis_lbl" xml:lang="en-US">Derivative Instrument [Axis]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockOptionMember" xlink:label="us-gaap_StockOptionMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockOptionMember" xlink:to="us-gaap_StockOptionMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StockOptionMember_lbl" xml:lang="en-US">Equity Option [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis" xlink:label="us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis" xlink:to="us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis_lbl" xml:lang="en-US">Exercise Price Range [Axis]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionPrice1Member" xlink:label="avxl_OptionPrice1Member" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_OptionPrice1Member" xlink:to="avxl_OptionPrice1Member_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_OptionPrice1Member_lbl" xml:lang="en-US">Option Price 1 [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionPrice2Member" xlink:label="avxl_OptionPrice2Member" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_OptionPrice2Member" xlink:to="avxl_OptionPrice2Member_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_OptionPrice2Member_lbl" xml:lang="en-US">Option Price 2 [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionPrice3Member" xlink:label="avxl_OptionPrice3Member" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_OptionPrice3Member" xlink:to="avxl_OptionPrice3Member_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_OptionPrice3Member_lbl" xml:lang="en-US">Option Price 3 [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionPrice4Member" xlink:label="avxl_OptionPrice4Member" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_OptionPrice4Member" xlink:to="avxl_OptionPrice4Member_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_OptionPrice4Member_lbl" xml:lang="en-US">Option Price 4 [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionPrice5Member" xlink:label="avxl_OptionPrice5Member" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_OptionPrice5Member" xlink:to="avxl_OptionPrice5Member_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_OptionPrice5Member_lbl" xml:lang="en-US">Option Price 5 [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="us-gaap_IncomeStatementLocationAxis" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeStatementLocationAxis" xlink:to="us-gaap_IncomeStatementLocationAxis_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeStatementLocationAxis_lbl" xml:lang="en-US">Income Statement Location [Axis]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_GeneralAndAdministrativeExpenseMember" xlink:label="us-gaap_GeneralAndAdministrativeExpenseMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_GeneralAndAdministrativeExpenseMember" xlink:to="us-gaap_GeneralAndAdministrativeExpenseMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_GeneralAndAdministrativeExpenseMember_lbl" xml:lang="en-US">General and Administrative Expense [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ResearchAndDevelopmentExpenseMember" xlink:label="us-gaap_ResearchAndDevelopmentExpenseMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ResearchAndDevelopmentExpenseMember" xlink:to="us-gaap_ResearchAndDevelopmentExpenseMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ResearchAndDevelopmentExpenseMember_lbl" xml:lang="en-US">Research and Development Expense [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxAuthorityAxis" xlink:label="us-gaap_IncomeTaxAuthorityAxis" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxAuthorityAxis" xlink:to="us-gaap_IncomeTaxAuthorityAxis_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeTaxAuthorityAxis_lbl" xml:lang="en-US">Income Tax Authority [Axis]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_FederalMember" xlink:label="avxl_FederalMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_FederalMember" xlink:to="avxl_FederalMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_FederalMember_lbl" xml:lang="en-US">Federal [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StateAndLocalJurisdictionMember" xlink:label="us-gaap_StateAndLocalJurisdictionMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StateAndLocalJurisdictionMember" xlink:to="us-gaap_StateAndLocalJurisdictionMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StateAndLocalJurisdictionMember_lbl" xml:lang="en-US">State and Local Jurisdiction [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ForeignCountryMember" xlink:label="us-gaap_ForeignCountryMember" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ForeignCountryMember" xlink:to="us-gaap_ForeignCountryMember_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ForeignCountryMember_lbl" xml:lang="en-US">Foreign Tax Authority [Member]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_CoverAbstract" xlink:label="dei_CoverAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_CoverAbstract" xlink:to="dei_CoverAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_CoverAbstract_lbl" xml:lang="en-US">Cover [Abstract]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentType" xlink:label="dei_DocumentType" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentType" xlink:to="dei_DocumentType_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentType_lbl" xml:lang="en-US">Document Type</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AmendmentFlag" xlink:label="dei_AmendmentFlag" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_AmendmentFlag" xlink:to="dei_AmendmentFlag_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_AmendmentFlag_lbl" xml:lang="en-US">Amendment Flag</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AmendmentDescription" xlink:label="dei_AmendmentDescription" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_AmendmentDescription" xlink:to="dei_AmendmentDescription_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_AmendmentDescription_lbl" xml:lang="en-US">Amendment Description</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentRegistrationStatement" xlink:label="dei_DocumentRegistrationStatement" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentRegistrationStatement" xlink:to="dei_DocumentRegistrationStatement_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentRegistrationStatement_lbl" xml:lang="en-US">Document Registration Statement</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentAnnualReport" xlink:label="dei_DocumentAnnualReport" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentAnnualReport" xlink:to="dei_DocumentAnnualReport_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentAnnualReport_lbl" xml:lang="en-US">Document Annual Report</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentQuarterlyReport" xlink:label="dei_DocumentQuarterlyReport" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentQuarterlyReport" xlink:to="dei_DocumentQuarterlyReport_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentQuarterlyReport_lbl" xml:lang="en-US">Document Quarterly Report</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentTransitionReport" xlink:label="dei_DocumentTransitionReport" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentTransitionReport" xlink:to="dei_DocumentTransitionReport_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentTransitionReport_lbl" xml:lang="en-US">Document Transition Report</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentShellCompanyReport" xlink:label="dei_DocumentShellCompanyReport" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentShellCompanyReport" xlink:to="dei_DocumentShellCompanyReport_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentShellCompanyReport_lbl" xml:lang="en-US">Document Shell Company Report</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentShellCompanyEventDate" xlink:label="dei_DocumentShellCompanyEventDate" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentShellCompanyEventDate" xlink:to="dei_DocumentShellCompanyEventDate_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentShellCompanyEventDate_lbl" xml:lang="en-US">Document Shell Company Event Date</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentPeriodStartDate" xlink:label="dei_DocumentPeriodStartDate" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentPeriodStartDate" xlink:to="dei_DocumentPeriodStartDate_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentPeriodStartDate_lbl" xml:lang="en-US">Document Period Start Date</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentPeriodEndDate" xlink:label="dei_DocumentPeriodEndDate" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentPeriodEndDate" xlink:to="dei_DocumentPeriodEndDate_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentPeriodEndDate_lbl" xml:lang="en-US">Document Period End Date</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentFiscalPeriodFocus" xlink:label="dei_DocumentFiscalPeriodFocus" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentFiscalPeriodFocus" xlink:to="dei_DocumentFiscalPeriodFocus_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentFiscalPeriodFocus_lbl" xml:lang="en-US">Document Fiscal Period Focus</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentFiscalYearFocus" xlink:label="dei_DocumentFiscalYearFocus" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentFiscalYearFocus" xlink:to="dei_DocumentFiscalYearFocus_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentFiscalYearFocus_lbl" xml:lang="en-US">Document Fiscal Year Focus</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_CurrentFiscalYearEndDate" xlink:label="dei_CurrentFiscalYearEndDate" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_CurrentFiscalYearEndDate" xlink:to="dei_CurrentFiscalYearEndDate_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_CurrentFiscalYearEndDate_lbl" xml:lang="en-US">Current Fiscal Year End Date</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityFileNumber" xlink:label="dei_EntityFileNumber" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityFileNumber" xlink:to="dei_EntityFileNumber_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityFileNumber_lbl" xml:lang="en-US">Entity File Number</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityRegistrantName" xlink:label="dei_EntityRegistrantName" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityRegistrantName" xlink:to="dei_EntityRegistrantName_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityRegistrantName_lbl" xml:lang="en-US">Entity Registrant Name</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityCentralIndexKey" xlink:label="dei_EntityCentralIndexKey" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityCentralIndexKey" xlink:to="dei_EntityCentralIndexKey_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityCentralIndexKey_lbl" xml:lang="en-US">Entity Central Index Key</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityPrimarySicNumber" xlink:label="dei_EntityPrimarySicNumber" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityPrimarySicNumber" xlink:to="dei_EntityPrimarySicNumber_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityPrimarySicNumber_lbl" xml:lang="en-US">Entity Primary SIC Number</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityTaxIdentificationNumber" xlink:label="dei_EntityTaxIdentificationNumber" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityTaxIdentificationNumber" xlink:to="dei_EntityTaxIdentificationNumber_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityTaxIdentificationNumber_lbl" xml:lang="en-US">Entity Tax Identification Number</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityIncorporationStateCountryCode" xlink:label="dei_EntityIncorporationStateCountryCode" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityIncorporationStateCountryCode" xlink:to="dei_EntityIncorporationStateCountryCode_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityIncorporationStateCountryCode_lbl" xml:lang="en-US">Entity Incorporation, State or Country Code</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressAddressLine1" xlink:label="dei_EntityAddressAddressLine1" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressAddressLine1" xlink:to="dei_EntityAddressAddressLine1_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressAddressLine1_lbl" xml:lang="en-US">Entity Address, Address Line One</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressAddressLine2" xlink:label="dei_EntityAddressAddressLine2" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressAddressLine2" xlink:to="dei_EntityAddressAddressLine2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressAddressLine2_lbl" xml:lang="en-US">Entity Address, Address Line Two</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressAddressLine3" xlink:label="dei_EntityAddressAddressLine3" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressAddressLine3" xlink:to="dei_EntityAddressAddressLine3_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressAddressLine3_lbl" xml:lang="en-US">Entity Address, Address Line Three</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressCityOrTown" xlink:label="dei_EntityAddressCityOrTown" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressCityOrTown" xlink:to="dei_EntityAddressCityOrTown_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressCityOrTown_lbl" xml:lang="en-US">Entity Address, City or Town</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressStateOrProvince" xlink:label="dei_EntityAddressStateOrProvince" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressStateOrProvince" xlink:to="dei_EntityAddressStateOrProvince_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressStateOrProvince_lbl" xml:lang="en-US">Entity Address, State or Province</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressCountry" xlink:label="dei_EntityAddressCountry" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressCountry" xlink:to="dei_EntityAddressCountry_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressCountry_lbl" xml:lang="en-US">Entity Address, Country</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressPostalZipCode" xlink:label="dei_EntityAddressPostalZipCode" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressPostalZipCode" xlink:to="dei_EntityAddressPostalZipCode_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressPostalZipCode_lbl" xml:lang="en-US">Entity Address, Postal Zip Code</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_CountryRegion" xlink:label="dei_CountryRegion" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_CountryRegion" xlink:to="dei_CountryRegion_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_CountryRegion_lbl" xml:lang="en-US">Country Region</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_CityAreaCode" xlink:label="dei_CityAreaCode" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_CityAreaCode" xlink:to="dei_CityAreaCode_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_CityAreaCode_lbl" xml:lang="en-US">City Area Code</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_LocalPhoneNumber" xlink:label="dei_LocalPhoneNumber" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_LocalPhoneNumber" xlink:to="dei_LocalPhoneNumber_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_LocalPhoneNumber_lbl" xml:lang="en-US">Local Phone Number</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_Extension" xlink:label="dei_Extension" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_Extension" xlink:to="dei_Extension_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_Extension_lbl" xml:lang="en-US">Extension</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_WrittenCommunications" xlink:label="dei_WrittenCommunications" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_WrittenCommunications" xlink:to="dei_WrittenCommunications_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_WrittenCommunications_lbl" xml:lang="en-US">Written Communications</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_SolicitingMaterial" xlink:label="dei_SolicitingMaterial" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_SolicitingMaterial" xlink:to="dei_SolicitingMaterial_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_SolicitingMaterial_lbl" xml:lang="en-US">Soliciting Material</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_PreCommencementTenderOffer" xlink:label="dei_PreCommencementTenderOffer" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_PreCommencementTenderOffer" xlink:to="dei_PreCommencementTenderOffer_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_PreCommencementTenderOffer_lbl" xml:lang="en-US">Pre-commencement Tender Offer</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_PreCommencementIssuerTenderOffer" xlink:label="dei_PreCommencementIssuerTenderOffer" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_PreCommencementIssuerTenderOffer" xlink:to="dei_PreCommencementIssuerTenderOffer_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_PreCommencementIssuerTenderOffer_lbl" xml:lang="en-US">Pre-commencement Issuer Tender Offer</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_Security12bTitle" xlink:label="dei_Security12bTitle" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_Security12bTitle" xlink:to="dei_Security12bTitle_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_Security12bTitle_lbl" xml:lang="en-US">Title of 12(b) Security</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_NoTradingSymbolFlag" xlink:label="dei_NoTradingSymbolFlag" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_NoTradingSymbolFlag" xlink:to="dei_NoTradingSymbolFlag_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_NoTradingSymbolFlag_lbl" xml:lang="en-US">No Trading Symbol Flag</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_TradingSymbol" xlink:label="dei_TradingSymbol" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_TradingSymbol" xlink:to="dei_TradingSymbol_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_TradingSymbol_lbl" xml:lang="en-US">Trading Symbol</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_SecurityExchangeName" xlink:label="dei_SecurityExchangeName" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_SecurityExchangeName" xlink:to="dei_SecurityExchangeName_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_SecurityExchangeName_lbl" xml:lang="en-US">Security Exchange Name</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_Security12gTitle" xlink:label="dei_Security12gTitle" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_Security12gTitle" xlink:to="dei_Security12gTitle_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_Security12gTitle_lbl" xml:lang="en-US">Title of 12(g) Security</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_SecurityReportingObligation" xlink:label="dei_SecurityReportingObligation" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_SecurityReportingObligation" xlink:to="dei_SecurityReportingObligation_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_SecurityReportingObligation_lbl" xml:lang="en-US">Security Reporting Obligation</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AnnualInformationForm" xlink:label="dei_AnnualInformationForm" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_AnnualInformationForm" xlink:to="dei_AnnualInformationForm_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_AnnualInformationForm_lbl" xml:lang="en-US">Annual Information Form</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AuditedAnnualFinancialStatements" xlink:label="dei_AuditedAnnualFinancialStatements" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_AuditedAnnualFinancialStatements" xlink:to="dei_AuditedAnnualFinancialStatements_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_AuditedAnnualFinancialStatements_lbl" xml:lang="en-US">Audited Annual Financial Statements</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityWellKnownSeasonedIssuer" xlink:label="dei_EntityWellKnownSeasonedIssuer" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityWellKnownSeasonedIssuer" xlink:to="dei_EntityWellKnownSeasonedIssuer_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityWellKnownSeasonedIssuer_lbl" xml:lang="en-US">Entity Well-known Seasoned Issuer</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityVoluntaryFilers" xlink:label="dei_EntityVoluntaryFilers" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityVoluntaryFilers" xlink:to="dei_EntityVoluntaryFilers_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityVoluntaryFilers_lbl" xml:lang="en-US">Entity Voluntary Filers</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityCurrentReportingStatus" xlink:label="dei_EntityCurrentReportingStatus" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityCurrentReportingStatus" xlink:to="dei_EntityCurrentReportingStatus_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityCurrentReportingStatus_lbl" xml:lang="en-US">Entity Current Reporting Status</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityInteractiveDataCurrent" xlink:label="dei_EntityInteractiveDataCurrent" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityInteractiveDataCurrent" xlink:to="dei_EntityInteractiveDataCurrent_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityInteractiveDataCurrent_lbl" xml:lang="en-US">Entity Interactive Data Current</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityFilerCategory" xlink:label="dei_EntityFilerCategory" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityFilerCategory" xlink:to="dei_EntityFilerCategory_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityFilerCategory_lbl" xml:lang="en-US">Entity Filer Category</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntitySmallBusiness" xlink:label="dei_EntitySmallBusiness" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntitySmallBusiness" xlink:to="dei_EntitySmallBusiness_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntitySmallBusiness_lbl" xml:lang="en-US">Entity Small Business</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityEmergingGrowthCompany" xlink:label="dei_EntityEmergingGrowthCompany" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityEmergingGrowthCompany" xlink:to="dei_EntityEmergingGrowthCompany_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityEmergingGrowthCompany_lbl" xml:lang="en-US">Entity Emerging Growth Company</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityExTransitionPeriod" xlink:label="dei_EntityExTransitionPeriod" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityExTransitionPeriod" xlink:to="dei_EntityExTransitionPeriod_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityExTransitionPeriod_lbl" xml:lang="en-US">Elected Not To Use the Extended Transition Period</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentAccountingStandard" xlink:label="dei_DocumentAccountingStandard" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentAccountingStandard" xlink:to="dei_DocumentAccountingStandard_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentAccountingStandard_lbl" xml:lang="en-US">Document Accounting Standard</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_OtherReportingStandardItemNumber" xlink:label="dei_OtherReportingStandardItemNumber" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_OtherReportingStandardItemNumber" xlink:to="dei_OtherReportingStandardItemNumber_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_OtherReportingStandardItemNumber_lbl" xml:lang="en-US">Other Reporting Standard Item Number</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityShellCompany" xlink:label="dei_EntityShellCompany" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityShellCompany" xlink:to="dei_EntityShellCompany_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityShellCompany_lbl" xml:lang="en-US">Entity Shell Company</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityPublicFloat" xlink:label="dei_EntityPublicFloat" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityPublicFloat" xlink:to="dei_EntityPublicFloat_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityPublicFloat_lbl" xml:lang="en-US">Entity Public Float</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityBankruptcyProceedingsReportingCurrent" xlink:label="dei_EntityBankruptcyProceedingsReportingCurrent" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityBankruptcyProceedingsReportingCurrent" xlink:to="dei_EntityBankruptcyProceedingsReportingCurrent_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityBankruptcyProceedingsReportingCurrent_lbl" xml:lang="en-US">Entity Bankruptcy Proceedings, Reporting Current</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityCommonStockSharesOutstanding" xlink:label="dei_EntityCommonStockSharesOutstanding" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityCommonStockSharesOutstanding" xlink:to="dei_EntityCommonStockSharesOutstanding_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityCommonStockSharesOutstanding_lbl" xml:lang="en-US">Entity Common Stock, Shares Outstanding</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentsIncorporatedByReferenceTextBlock" xlink:label="dei_DocumentsIncorporatedByReferenceTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentsIncorporatedByReferenceTextBlock" xlink:to="dei_DocumentsIncorporatedByReferenceTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentsIncorporatedByReferenceTextBlock_lbl" xml:lang="en-US">Documents Incorporated by Reference [Text Block]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_IcfrAuditorAttestationFlag" xlink:label="dei_IcfrAuditorAttestationFlag" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_IcfrAuditorAttestationFlag" xlink:to="dei_IcfrAuditorAttestationFlag_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_IcfrAuditorAttestationFlag_lbl" xml:lang="en-US">ICFR Auditor Attestation Flag</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentFinStmtErrorCorrectionFlag" xlink:label="dei_DocumentFinStmtErrorCorrectionFlag" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentFinStmtErrorCorrectionFlag" xlink:to="dei_DocumentFinStmtErrorCorrectionFlag_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentFinStmtErrorCorrectionFlag_lbl" xml:lang="en-US">Document Financial Statement Error Correction [Flag]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AuditorName" xlink:label="dei_AuditorName" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_AuditorName" xlink:to="dei_AuditorName_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_AuditorName_lbl" xml:lang="en-US">Auditor Name</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AuditorLocation" xlink:label="dei_AuditorLocation" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_AuditorLocation" xlink:to="dei_AuditorLocation_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_AuditorLocation_lbl" xml:lang="en-US">Auditor Location</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AuditorFirmId" xlink:label="dei_AuditorFirmId" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_AuditorFirmId" xlink:to="dei_AuditorFirmId_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_AuditorFirmId_lbl" xml:lang="en-US">Auditor Firm ID</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="us-gaap_StatementOfFinancialPositionAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementOfFinancialPositionAbstract" xlink:to="us-gaap_StatementOfFinancialPositionAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementOfFinancialPositionAbstract_lbl" xml:lang="en-US">Statement of Financial Position [Abstract]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AssetsAbstract" xlink:label="us-gaap_AssetsAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AssetsAbstract" xlink:to="us-gaap_AssetsAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AssetsAbstract_lbl" xml:lang="en-US">Assets</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="us-gaap_AssetsCurrentAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AssetsCurrentAbstract" xlink:to="us-gaap_AssetsCurrentAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AssetsCurrentAbstract_lbl" xml:lang="en-US">Current</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="us-gaap_CashAndCashEquivalentsAtCarryingValue" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:to="us-gaap_CashAndCashEquivalentsAtCarryingValue_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CashAndCashEquivalentsAtCarryingValue_lbl" xml:lang="en-US">Cash and cash equivalents</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxesReceivable" xlink:label="us-gaap_IncomeTaxesReceivable" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxesReceivable" xlink:to="us-gaap_IncomeTaxesReceivable_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeTaxesReceivable_lbl" xml:lang="en-US">Incentive and tax receivables</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="us-gaap_PrepaidExpenseAndOtherAssetsCurrent" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:to="us-gaap_PrepaidExpenseAndOtherAssetsCurrent_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PrepaidExpenseAndOtherAssetsCurrent_lbl" xml:lang="en-US">Prepaid expenses and other current assets</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_Assets" xlink:label="us-gaap_Assets" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_Assets" xlink:to="us-gaap_Assets_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_Assets_lbl" xml:lang="en-US">Total Assets</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="us-gaap_LiabilitiesAndStockholdersEquityAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:to="us-gaap_LiabilitiesAndStockholdersEquityAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LiabilitiesAndStockholdersEquityAbstract_lbl" xml:lang="en-US">Liabilities and Stockholders' Equity</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="us-gaap_LiabilitiesCurrentAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LiabilitiesCurrentAbstract" xlink:to="us-gaap_LiabilitiesCurrentAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LiabilitiesCurrentAbstract_lbl" xml:lang="en-US">Current Liabilities</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccountsPayableCurrent" xlink:label="us-gaap_AccountsPayableCurrent" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccountsPayableCurrent" xlink:to="us-gaap_AccountsPayableCurrent_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccountsPayableCurrent_lbl" xml:lang="en-US">Accounts payable</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="us-gaap_AccruedLiabilitiesCurrent" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccruedLiabilitiesCurrent" xlink:to="us-gaap_AccruedLiabilitiesCurrent_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccruedLiabilitiesCurrent_lbl" xml:lang="en-US">Accrued liabilities - Note 3</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredRentCredit" xlink:label="us-gaap_DeferredRentCredit" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredRentCredit" xlink:to="us-gaap_DeferredRentCredit_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DeferredRentCredit_lbl" xml:lang="en-US">Deferred grant income - Note 4</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_Liabilities" xlink:label="us-gaap_Liabilities" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_Liabilities" xlink:to="us-gaap_Liabilities_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_Liabilities_lbl" xml:lang="en-US">Total Liabilities</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingencies" xlink:label="us-gaap_CommitmentsAndContingencies" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommitmentsAndContingencies" xlink:to="us-gaap_CommitmentsAndContingencies_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommitmentsAndContingencies_lbl" xml:lang="en-US">Commitments and Contingencies - Note 6</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PreferredStockValue" xlink:label="us-gaap_PreferredStockValue" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockValue" xlink:to="us-gaap_PreferredStockValue_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PreferredStockValue_lbl" xml:lang="en-US">Capital stock Authorized:10,000,000 preferred stock, par value $0.001 per share</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockValue" xlink:label="us-gaap_CommonStockValue" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockValue" xlink:to="us-gaap_CommonStockValue_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonStockValue_lbl" xml:lang="en-US">Capital stock Authorized: 200,000,000 common stock, par value $0.001 per Issued and outstanding: 82,066,511 common shares (2022 - 77,942,815)</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AdditionalPaidInCapitalCommonStock" xlink:label="us-gaap_AdditionalPaidInCapitalCommonStock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AdditionalPaidInCapitalCommonStock" xlink:to="us-gaap_AdditionalPaidInCapitalCommonStock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AdditionalPaidInCapitalCommonStock_lbl" xml:lang="en-US">Additional paid-in capital</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="us-gaap_RetainedEarningsAccumulatedDeficit" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_RetainedEarningsAccumulatedDeficit" xlink:to="us-gaap_RetainedEarningsAccumulatedDeficit_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_RetainedEarningsAccumulatedDeficit_lbl" xml:lang="en-US">Accumulated deficit</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockholdersEquity" xlink:label="us-gaap_StockholdersEquity" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockholdersEquity" xlink:to="us-gaap_StockholdersEquity_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_StockholdersEquity_lbl" xml:lang="en-US">Total Stockholders' Equity</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="us-gaap_LiabilitiesAndStockholdersEquity" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LiabilitiesAndStockholdersEquity" xlink:to="us-gaap_LiabilitiesAndStockholdersEquity_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_LiabilitiesAndStockholdersEquity_lbl" xml:lang="en-US">Total Liabilities and Stockholders' Equity</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PreferredStockSharesAuthorized" xlink:label="us-gaap_PreferredStockSharesAuthorized" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockSharesAuthorized" xlink:to="us-gaap_PreferredStockSharesAuthorized_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PreferredStockSharesAuthorized_lbl" xml:lang="en-US">Preferred stock, authorized</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PreferredStockParOrStatedValuePerShare" xlink:label="us-gaap_PreferredStockParOrStatedValuePerShare" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockParOrStatedValuePerShare" xlink:to="us-gaap_PreferredStockParOrStatedValuePerShare_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PreferredStockParOrStatedValuePerShare_lbl" xml:lang="en-US">Preferred stock, par value</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockSharesAuthorized" xlink:label="us-gaap_CommonStockSharesAuthorized" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockSharesAuthorized" xlink:to="us-gaap_CommonStockSharesAuthorized_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonStockSharesAuthorized_lbl" xml:lang="en-US">Common shares, authorized</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockParOrStatedValuePerShare" xlink:label="us-gaap_CommonStockParOrStatedValuePerShare" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockParOrStatedValuePerShare" xlink:to="us-gaap_CommonStockParOrStatedValuePerShare_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonStockParOrStatedValuePerShare_lbl" xml:lang="en-US">Common shares, par value</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockSharesIssued" xlink:label="us-gaap_CommonStockSharesIssued" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockSharesIssued" xlink:to="us-gaap_CommonStockSharesIssued_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonStockSharesIssued_lbl" xml:lang="en-US">Common shares, issued</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockSharesOutstanding" xlink:label="us-gaap_CommonStockSharesOutstanding" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockSharesOutstanding" xlink:to="us-gaap_CommonStockSharesOutstanding_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonStockSharesOutstanding_lbl" xml:lang="en-US">Common shares, outstanding</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeStatementAbstract" xlink:label="us-gaap_IncomeStatementAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeStatementAbstract" xlink:to="us-gaap_IncomeStatementAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeStatementAbstract_lbl" xml:lang="en-US">Income Statement [Abstract]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingExpensesAbstract" xlink:label="us-gaap_OperatingExpensesAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingExpensesAbstract" xlink:to="us-gaap_OperatingExpensesAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingExpensesAbstract_lbl" xml:lang="en-US">Operating expenses</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_GeneralAndAdministrativeExpense" xlink:label="us-gaap_GeneralAndAdministrativeExpense" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_GeneralAndAdministrativeExpense" xlink:to="us-gaap_GeneralAndAdministrativeExpense_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_GeneralAndAdministrativeExpense_lbl" xml:lang="en-US">General and administrative</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ResearchAndDevelopmentExpense" xlink:label="us-gaap_ResearchAndDevelopmentExpense" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ResearchAndDevelopmentExpense" xlink:to="us-gaap_ResearchAndDevelopmentExpense_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ResearchAndDevelopmentExpense_lbl" xml:lang="en-US">Research and development</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingExpenses" xlink:label="us-gaap_OperatingExpenses" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingExpenses" xlink:to="us-gaap_OperatingExpenses_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_OperatingExpenses_lbl" xml:lang="en-US">Total operating expenses</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingIncomeLoss" xlink:label="us-gaap_OperatingIncomeLoss" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingIncomeLoss" xlink:to="us-gaap_OperatingIncomeLoss_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_OperatingIncomeLoss_lbl" xml:lang="en-US">Operating loss</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NonoperatingIncomeExpenseAbstract" xlink:label="us-gaap_NonoperatingIncomeExpenseAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NonoperatingIncomeExpenseAbstract" xlink:to="us-gaap_NonoperatingIncomeExpenseAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NonoperatingIncomeExpenseAbstract_lbl" xml:lang="en-US">Other income (expenses)</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_NonOperatingIncomeFromGrants" xlink:label="avxl_NonOperatingIncomeFromGrants" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_NonOperatingIncomeFromGrants" xlink:to="avxl_NonOperatingIncomeFromGrants_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_NonOperatingIncomeFromGrants_lbl" xml:lang="en-US">Grant income</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ResearchAndDevelopmentIncentiveIncome" xlink:label="avxl_ResearchAndDevelopmentIncentiveIncome" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_ResearchAndDevelopmentIncentiveIncome" xlink:to="avxl_ResearchAndDevelopmentIncentiveIncome_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_ResearchAndDevelopmentIncentiveIncome_lbl" xml:lang="en-US">Research and development incentive income</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InterestIncomeExpenseNet" xlink:label="us-gaap_InterestIncomeExpenseNet" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InterestIncomeExpenseNet" xlink:to="us-gaap_InterestIncomeExpenseNet_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_InterestIncomeExpenseNet_lbl" xml:lang="en-US">Interest income, net</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OtherFinancingExpense" xlink:label="avxl_OtherFinancingExpense" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_OtherFinancingExpense" xlink:to="avxl_OtherFinancingExpense_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="avxl_OtherFinancingExpense_lbl" xml:lang="en-US">Other financing expense</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ForeignCurrencyTransactionGainLossBeforeTax" xlink:label="us-gaap_ForeignCurrencyTransactionGainLossBeforeTax" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ForeignCurrencyTransactionGainLossBeforeTax" xlink:to="us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_lbl" xml:lang="en-US">Foreign exchange loss</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NonoperatingIncomeExpense" xlink:label="us-gaap_NonoperatingIncomeExpense" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NonoperatingIncomeExpense" xlink:to="us-gaap_NonoperatingIncomeExpense_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_NonoperatingIncomeExpense_lbl" xml:lang="en-US">Total other income, net</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:label="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:to="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_lbl" xml:lang="en-US">Net loss before provision for income taxes</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CurrentIncomeTaxExpenseBenefit" xlink:label="us-gaap_CurrentIncomeTaxExpenseBenefit" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CurrentIncomeTaxExpenseBenefit" xlink:to="us-gaap_CurrentIncomeTaxExpenseBenefit_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_CurrentIncomeTaxExpenseBenefit_lbl" xml:lang="en-US">Income tax expense, current</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetIncomeLoss" xlink:label="us-gaap_NetIncomeLoss" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetIncomeLoss" xlink:to="us-gaap_NetIncomeLoss_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NetIncomeLoss_lbl" xml:lang="en-US">Net loss and comprehensive loss</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_EarningPerShareBasicAndDilutedAbstract" xlink:label="avxl_EarningPerShareBasicAndDilutedAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_EarningPerShareBasicAndDilutedAbstract" xlink:to="avxl_EarningPerShareBasicAndDilutedAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_EarningPerShareBasicAndDilutedAbstract_lbl" xml:lang="en-US">Net Loss per share Basic and diluted</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:to="us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_lbl" xml:lang="en-US">Weighted average number of shares outstanding Basic and diluted</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EarningsPerShareBasic" xlink:label="us-gaap_EarningsPerShareBasic" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_EarningsPerShareBasic" xlink:to="us-gaap_EarningsPerShareBasic_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_EarningsPerShareBasic_lbl" xml:lang="en-US">Net Loss per share, Basic</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EarningsPerShareDiluted" xlink:label="us-gaap_EarningsPerShareDiluted" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_EarningsPerShareDiluted" xlink:to="us-gaap_EarningsPerShareDiluted_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_EarningsPerShareDiluted_lbl" xml:lang="en-US">Net Loss per share, Diluted</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:to="us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_lbl" xml:lang="en-US">Weighted average number of shares outstanding, Basic</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:to="us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_lbl" xml:lang="en-US">Weighted average number of shares outstanding, Diluted</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="us-gaap_StatementOfCashFlowsAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementOfCashFlowsAbstract" xlink:to="us-gaap_StatementOfCashFlowsAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementOfCashFlowsAbstract_lbl" xml:lang="en-US">Statement of Cash Flows [Abstract]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract" xlink:to="us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_lbl" xml:lang="en-US">Cash Flows used in Operating Activities</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetIncomeLoss" xlink:to="us-gaap_NetIncomeLoss_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_NetIncomeLoss_2_lbl" xml:lang="en-US">Net loss</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:to="us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_lbl" xml:lang="en-US">Adjustments to reconcile net loss to net cash used in operations:</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_NoncashFinancingRelatedCharges" xlink:label="avxl_NoncashFinancingRelatedCharges" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_NoncashFinancingRelatedCharges" xlink:to="avxl_NoncashFinancingRelatedCharges_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_NoncashFinancingRelatedCharges_lbl" xml:lang="en-US">Non-cash financing related charges</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensation" xlink:label="us-gaap_ShareBasedCompensation" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensation" xlink:to="us-gaap_ShareBasedCompensation_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensation_lbl" xml:lang="en-US">Stock-based compensation</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:to="us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_lbl" xml:lang="en-US">Changes in working capital balances related to operations:</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInIncomeTaxesReceivable" xlink:label="us-gaap_IncreaseDecreaseInIncomeTaxesReceivable" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInIncomeTaxesReceivable" xlink:to="us-gaap_IncreaseDecreaseInIncomeTaxesReceivable_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_IncreaseDecreaseInIncomeTaxesReceivable_lbl" xml:lang="en-US">Incentive and tax receivables</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInPrepaidExpense" xlink:label="us-gaap_IncreaseDecreaseInPrepaidExpense" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInPrepaidExpense" xlink:to="us-gaap_IncreaseDecreaseInPrepaidExpense_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_IncreaseDecreaseInPrepaidExpense_lbl" xml:lang="en-US">Prepaid expenses and deposits</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInAccountsPayable" xlink:label="us-gaap_IncreaseDecreaseInAccountsPayable" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInAccountsPayable" xlink:to="us-gaap_IncreaseDecreaseInAccountsPayable_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_IncreaseDecreaseInAccountsPayable_lbl" xml:lang="en-US">Accounts payable</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilities" xlink:label="us-gaap_IncreaseDecreaseInAccruedLiabilities" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInAccruedLiabilities" xlink:to="us-gaap_IncreaseDecreaseInAccruedLiabilities_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncreaseDecreaseInAccruedLiabilities_lbl" xml:lang="en-US">Accrued liabilities</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DeferredGrantIncome" xlink:label="avxl_DeferredGrantIncome" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_DeferredGrantIncome" xlink:to="avxl_DeferredGrantIncome_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="avxl_DeferredGrantIncome_lbl" xml:lang="en-US">Deferred grant income</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivities" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:to="us-gaap_NetCashProvidedByUsedInOperatingActivities_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivities_lbl" xml:lang="en-US">Net cash used in operating activities</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract" xlink:to="us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_lbl" xml:lang="en-US">Cash Flows provided by Financing Activities</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock" xlink:label="us-gaap_ProceedsFromIssuanceOfCommonStock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ProceedsFromIssuanceOfCommonStock" xlink:to="us-gaap_ProceedsFromIssuanceOfCommonStock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ProceedsFromIssuanceOfCommonStock_lbl" xml:lang="en-US">Issuance of common shares</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PaymentsOfStockIssuanceCosts" xlink:label="us-gaap_PaymentsOfStockIssuanceCosts" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PaymentsOfStockIssuanceCosts" xlink:to="us-gaap_PaymentsOfStockIssuanceCosts_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_PaymentsOfStockIssuanceCosts_lbl" xml:lang="en-US">Share issue costs</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromWarrantExercises" xlink:label="us-gaap_ProceedsFromWarrantExercises" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ProceedsFromWarrantExercises" xlink:to="us-gaap_ProceedsFromWarrantExercises_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ProceedsFromWarrantExercises_lbl" xml:lang="en-US">Proceeds from exercise of warrants</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromStockOptionsExercised" xlink:label="us-gaap_ProceedsFromStockOptionsExercised" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ProceedsFromStockOptionsExercised" xlink:to="us-gaap_ProceedsFromStockOptionsExercised_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ProceedsFromStockOptionsExercised_lbl" xml:lang="en-US">Proceeds from exercise of stock options</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivities" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:to="us-gaap_NetCashProvidedByUsedInFinancingActivities_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivities_lbl" xml:lang="en-US">Net cash provided by financing activities</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:to="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect_lbl" xml:lang="en-US">Increase in cash and cash equivalents during the period</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:to="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_lbl" xml:lang="en-US">Cash and cash equivalents, beginning of period</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:to="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_2_lbl" xml:lang="en-US">Cash and cash equivalents, end of period</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="us-gaap_SupplementalCashFlowInformationAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SupplementalCashFlowInformationAbstract" xlink:to="us-gaap_SupplementalCashFlowInformationAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SupplementalCashFlowInformationAbstract_lbl" xml:lang="en-US">Supplemental Cash Flow Information</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CashPaidForStateAndLocalMinimumIncomeTaxes" xlink:label="avxl_CashPaidForStateAndLocalMinimumIncomeTaxes" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_CashPaidForStateAndLocalMinimumIncomeTaxes" xlink:to="avxl_CashPaidForStateAndLocalMinimumIncomeTaxes_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_CashPaidForStateAndLocalMinimumIncomeTaxes_lbl" xml:lang="en-US">Cash paid for state and local minimum income taxes</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementTable" xlink:label="us-gaap_StatementTable" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementTable" xlink:to="us-gaap_StatementTable_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementTable_lbl" xml:lang="en-US">Statement [Table]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementLineItems" xlink:label="us-gaap_StatementLineItems" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementLineItems" xlink:to="us-gaap_StatementLineItems_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementLineItems_lbl" xml:lang="en-US">Statement [Line Items]</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockholdersEquity" xlink:to="us-gaap_StockholdersEquity_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="us-gaap_StockholdersEquity_2_lbl" xml:lang="en-US">Beginning balance, value</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharesOutstanding" xlink:label="us-gaap_SharesOutstanding" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharesOutstanding" xlink:to="us-gaap_SharesOutstanding_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="us-gaap_SharesOutstanding_lbl" xml:lang="en-US">Balance at beginning, shares</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares" xlink:label="avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares" xlink:to="avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares_lbl" xml:lang="en-US">Shares issued under 2023 purchase agreement Initial Commitment shares</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares" xlink:label="avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares" xlink:to="avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares_lbl" xml:lang="en-US">Shares issued under 2023 purchase agreement Initial Commitment shares, shares</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockRepurchasedDuringPeriodValue" xlink:label="us-gaap_StockRepurchasedDuringPeriodValue" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockRepurchasedDuringPeriodValue" xlink:to="us-gaap_StockRepurchasedDuringPeriodValue_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StockRepurchasedDuringPeriodValue_lbl" xml:lang="en-US">Purchase shares</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockRepurchasedDuringPeriodShares" xlink:label="us-gaap_StockRepurchasedDuringPeriodShares" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockRepurchasedDuringPeriodShares" xlink:to="us-gaap_StockRepurchasedDuringPeriodShares_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StockRepurchasedDuringPeriodShares_lbl" xml:lang="en-US">Purchase shares, shares</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CommitmentShares" xlink:label="avxl_CommitmentShares" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_CommitmentShares" xlink:to="avxl_CommitmentShares_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_CommitmentShares_lbl" xml:lang="en-US">Commitment shares</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CommitmentSharesShares" xlink:label="avxl_CommitmentSharesShares" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_CommitmentSharesShares" xlink:to="avxl_CommitmentSharesShares_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_CommitmentSharesShares_lbl" xml:lang="en-US">Commitment shares, shares</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedUnderSalesAgreement" xlink:label="avxl_SharesIssuedUnderSalesAgreement" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_SharesIssuedUnderSalesAgreement" xlink:to="avxl_SharesIssuedUnderSalesAgreement_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_SharesIssuedUnderSalesAgreement_lbl" xml:lang="en-US">Shares issued under Sales Agreement</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedUnderSalesAgreementShares" xlink:label="avxl_SharesIssuedUnderSalesAgreementShares" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_SharesIssuedUnderSalesAgreementShares" xlink:to="avxl_SharesIssuedUnderSalesAgreementShares_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_SharesIssuedUnderSalesAgreementShares_lbl" xml:lang="en-US">Shares issued under Sales Agreement, shares</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_LessSalesAgreementShareIssueCosts" xlink:label="avxl_LessSalesAgreementShareIssueCosts" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_LessSalesAgreementShareIssueCosts" xlink:to="avxl_LessSalesAgreementShareIssueCosts_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_LessSalesAgreementShareIssueCosts_lbl" xml:lang="en-US">Less: share issue costs</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPursuantToRegisteredDirectOffering" xlink:label="avxl_SharesIssuedPursuantToRegisteredDirectOffering" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_SharesIssuedPursuantToRegisteredDirectOffering" xlink:to="avxl_SharesIssuedPursuantToRegisteredDirectOffering_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_SharesIssuedPursuantToRegisteredDirectOffering_lbl" xml:lang="en-US">Shares issued pursuant to registered direct offering</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPursuantToRegisteredDirectOfferingShares" xlink:label="avxl_SharesIssuedPursuantToRegisteredDirectOfferingShares" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_SharesIssuedPursuantToRegisteredDirectOfferingShares" xlink:to="avxl_SharesIssuedPursuantToRegisteredDirectOfferingShares_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_SharesIssuedPursuantToRegisteredDirectOfferingShares_lbl" xml:lang="en-US">Shares issued pursuant to registered direct offering, shares</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_LessRegisteredDirectOfferingShareIssueCosts" xlink:label="avxl_LessRegisteredDirectOfferingShareIssueCosts" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_LessRegisteredDirectOfferingShareIssueCosts" xlink:to="avxl_LessRegisteredDirectOfferingShareIssueCosts_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="avxl_LessRegisteredDirectOfferingShareIssueCosts_lbl" xml:lang="en-US">Less: share issue costs</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPursuantToExerciseOfStockOptions" xlink:label="avxl_SharesIssuedPursuantToExerciseOfStockOptions" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_SharesIssuedPursuantToExerciseOfStockOptions" xlink:to="avxl_SharesIssuedPursuantToExerciseOfStockOptions_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_SharesIssuedPursuantToExerciseOfStockOptions_lbl" xml:lang="en-US">Shares issued pursuant to exercise of stock options</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPursuantToExerciseOfStockOptionsShares" xlink:label="avxl_SharesIssuedPursuantToExerciseOfStockOptionsShares" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_SharesIssuedPursuantToExerciseOfStockOptionsShares" xlink:to="avxl_SharesIssuedPursuantToExerciseOfStockOptionsShares_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_SharesIssuedPursuantToExerciseOfStockOptionsShares_lbl" xml:lang="en-US">Shares issued pursuant to exercise of stock options, shares</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPusuantToExerciseOfWarrants" xlink:label="avxl_SharesIssuedPusuantToExerciseOfWarrants" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_SharesIssuedPusuantToExerciseOfWarrants" xlink:to="avxl_SharesIssuedPusuantToExerciseOfWarrants_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_SharesIssuedPusuantToExerciseOfWarrants_lbl" xml:lang="en-US">Shares issued pursuant to exercise of warrants</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPusuantToExerciseOfWarrantsShares" xlink:label="avxl_SharesIssuedPusuantToExerciseOfWarrantsShares" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_SharesIssuedPusuantToExerciseOfWarrantsShares" xlink:to="avxl_SharesIssuedPusuantToExerciseOfWarrantsShares_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_SharesIssuedPusuantToExerciseOfWarrantsShares_lbl" xml:lang="en-US">Shares issued pusuant to exercise of warrants, shares</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:label="us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:to="us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_lbl" xml:lang="en-US">Share based compensation</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockholdersEquity" xlink:to="us-gaap_StockholdersEquity_3_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="us-gaap_StockholdersEquity_3_lbl" xml:lang="en-US">Ending balance, value</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharesOutstanding" xlink:to="us-gaap_SharesOutstanding_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="us-gaap_SharesOutstanding_2_lbl" xml:lang="en-US">Balance at ending, shares</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:to="us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_lbl" xml:lang="en-US">Organization, Consolidation and Presentation of Financial Statements [Abstract]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock" xlink:label="us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock" xlink:to="us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_lbl" xml:lang="en-US">Business Description and Basis of Presentation</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="us-gaap_AccountingPoliciesAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccountingPoliciesAbstract" xlink:to="us-gaap_AccountingPoliciesAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccountingPoliciesAbstract_lbl" xml:lang="en-US">Accounting Policies [Abstract]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SignificantAccountingPoliciesTextBlock" xlink:label="us-gaap_SignificantAccountingPoliciesTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SignificantAccountingPoliciesTextBlock" xlink:to="us-gaap_SignificantAccountingPoliciesTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SignificantAccountingPoliciesTextBlock_lbl" xml:lang="en-US">Summary of Significant Accounting Policies</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DisclosureAccruedLiabilitiesAbstract" xlink:label="avxl_DisclosureAccruedLiabilitiesAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_DisclosureAccruedLiabilitiesAbstract" xlink:to="avxl_DisclosureAccruedLiabilitiesAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_DisclosureAccruedLiabilitiesAbstract_lbl" xml:lang="en-US">Accrued Liabilities</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_AccuredLiabilitiesTextBlock" xlink:label="avxl_AccuredLiabilitiesTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_AccuredLiabilitiesTextBlock" xlink:to="avxl_AccuredLiabilitiesTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="avxl_AccuredLiabilitiesTextBlock_lbl" xml:lang="en-US">Accrued Liabilities</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DisclosureOtherIncomeAbstract" xlink:label="avxl_DisclosureOtherIncomeAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_DisclosureOtherIncomeAbstract" xlink:to="avxl_DisclosureOtherIncomeAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_DisclosureOtherIncomeAbstract_lbl" xml:lang="en-US">Other Income</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OtherIncomeDisclosureTextBlock" xlink:label="avxl_OtherIncomeDisclosureTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_OtherIncomeDisclosureTextBlock" xlink:to="avxl_OtherIncomeDisclosureTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="avxl_OtherIncomeDisclosureTextBlock_lbl" xml:lang="en-US">Other Income</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DisclosureEquityOfferingsAbstract" xlink:label="avxl_DisclosureEquityOfferingsAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_DisclosureEquityOfferingsAbstract" xlink:to="avxl_DisclosureEquityOfferingsAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_DisclosureEquityOfferingsAbstract_lbl" xml:lang="en-US">Equity Offerings</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_EquityOfferingTextBlock" xlink:label="avxl_EquityOfferingTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_EquityOfferingTextBlock" xlink:to="avxl_EquityOfferingTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="avxl_EquityOfferingTextBlock_lbl" xml:lang="en-US">Equity Offerings</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="us-gaap_CommitmentsAndContingenciesDisclosureAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:to="us-gaap_CommitmentsAndContingenciesDisclosureAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommitmentsAndContingenciesDisclosureAbstract_lbl" xml:lang="en-US">Commitments and Contingencies Disclosure [Abstract]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsDisclosureTextBlock" xlink:label="us-gaap_CommitmentsDisclosureTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommitmentsDisclosureTextBlock" xlink:to="us-gaap_CommitmentsDisclosureTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommitmentsDisclosureTextBlock_lbl" xml:lang="en-US">Commitments and Contingencies</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="us-gaap_IncomeTaxDisclosureAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxDisclosureAbstract" xlink:to="us-gaap_IncomeTaxDisclosureAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeTaxDisclosureAbstract_lbl" xml:lang="en-US">Income Tax Disclosure [Abstract]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxDisclosureTextBlock" xlink:label="us-gaap_IncomeTaxDisclosureTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxDisclosureTextBlock" xlink:to="us-gaap_IncomeTaxDisclosureTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeTaxDisclosureTextBlock_lbl" xml:lang="en-US">Income Taxes</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SubsequentEventsAbstract" xlink:label="us-gaap_SubsequentEventsAbstract" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SubsequentEventsAbstract" xlink:to="us-gaap_SubsequentEventsAbstract_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SubsequentEventsAbstract_lbl" xml:lang="en-US">Subsequent Events [Abstract]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SubsequentEventsTextBlock" xlink:label="us-gaap_SubsequentEventsTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SubsequentEventsTextBlock" xlink:to="us-gaap_SubsequentEventsTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SubsequentEventsTextBlock_lbl" xml:lang="en-US">Subsequent Events</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_UseOfEstimates" xlink:label="us-gaap_UseOfEstimates" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_UseOfEstimates" xlink:to="us-gaap_UseOfEstimates_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_UseOfEstimates_lbl" xml:lang="en-US">Use of Estimates</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ConsolidationPolicyTextBlock" xlink:label="us-gaap_ConsolidationPolicyTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ConsolidationPolicyTextBlock" xlink:to="us-gaap_ConsolidationPolicyTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ConsolidationPolicyTextBlock_lbl" xml:lang="en-US">Principles of Consolidation</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashAndCashEquivalentsPolicyTextBlock" xlink:label="us-gaap_CashAndCashEquivalentsPolicyTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashAndCashEquivalentsPolicyTextBlock" xlink:to="us-gaap_CashAndCashEquivalentsPolicyTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CashAndCashEquivalentsPolicyTextBlock_lbl" xml:lang="en-US">Cash and equivalents</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ResearchAndDevelopmentExpensePolicy" xlink:label="us-gaap_ResearchAndDevelopmentExpensePolicy" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ResearchAndDevelopmentExpensePolicy" xlink:to="us-gaap_ResearchAndDevelopmentExpensePolicy_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ResearchAndDevelopmentExpensePolicy_lbl" xml:lang="en-US">Research and Development Expenses</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RevenueRecognitionIncentives" xlink:label="us-gaap_RevenueRecognitionIncentives" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_RevenueRecognitionIncentives" xlink:to="us-gaap_RevenueRecognitionIncentives_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_RevenueRecognitionIncentives_lbl" xml:lang="en-US">Research and Development Incentive Income</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_LicenseFeesPolicyTextBlock" xlink:label="avxl_LicenseFeesPolicyTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_LicenseFeesPolicyTextBlock" xlink:to="avxl_LicenseFeesPolicyTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_LicenseFeesPolicyTextBlock_lbl" xml:lang="en-US">License Fees</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EarningsPerSharePolicyTextBlock" xlink:label="us-gaap_EarningsPerSharePolicyTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_EarningsPerSharePolicyTextBlock" xlink:to="us-gaap_EarningsPerSharePolicyTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_EarningsPerSharePolicyTextBlock_lbl" xml:lang="en-US">Basic and Diluted Loss per Share</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FairValueOfFinancialInstrumentsPolicy" xlink:label="us-gaap_FairValueOfFinancialInstrumentsPolicy" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_FairValueOfFinancialInstrumentsPolicy" xlink:to="us-gaap_FairValueOfFinancialInstrumentsPolicy_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_FairValueOfFinancialInstrumentsPolicy_lbl" xml:lang="en-US">Financial Instruments</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock" xlink:label="us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock" xlink:to="us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_lbl" xml:lang="en-US">Foreign Currency Translation</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SegmentReportingPolicyPolicyTextBlock" xlink:label="us-gaap_SegmentReportingPolicyPolicyTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SegmentReportingPolicyPolicyTextBlock" xlink:to="us-gaap_SegmentReportingPolicyPolicyTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SegmentReportingPolicyPolicyTextBlock_lbl" xml:lang="en-US">Segment and Geographic Reporting</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_GrantIncomePolicyTextBlock" xlink:label="avxl_GrantIncomePolicyTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_GrantIncomePolicyTextBlock" xlink:to="avxl_GrantIncomePolicyTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_GrantIncomePolicyTextBlock_lbl" xml:lang="en-US">Grant Income</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxPolicyTextBlock" xlink:label="us-gaap_IncomeTaxPolicyTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxPolicyTextBlock" xlink:to="us-gaap_IncomeTaxPolicyTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_IncomeTaxPolicyTextBlock_lbl" xml:lang="en-US">Income Taxes</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationForfeituresPolicyTextBlock" xlink:label="us-gaap_ShareBasedCompensationForfeituresPolicyTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationForfeituresPolicyTextBlock" xlink:to="us-gaap_ShareBasedCompensationForfeituresPolicyTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationForfeituresPolicyTextBlock_lbl" xml:lang="en-US">Stock-based Compensation</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FairValueMeasurementPolicyPolicyTextBlock" xlink:label="us-gaap_FairValueMeasurementPolicyPolicyTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_FairValueMeasurementPolicyPolicyTextBlock" xlink:to="us-gaap_FairValueMeasurementPolicyPolicyTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_FairValueMeasurementPolicyPolicyTextBlock_lbl" xml:lang="en-US">Fair Value Measurements</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:label="us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:to="us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_lbl" xml:lang="en-US">Recently Adopted Accounting Pronouncements</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock" xlink:label="us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock" xlink:to="us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_lbl" xml:lang="en-US">Schedule of principal components of accrued liabilities</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LeaseCostTableTextBlock" xlink:label="us-gaap_LeaseCostTableTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LeaseCostTableTextBlock" xlink:to="us-gaap_LeaseCostTableTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LeaseCostTableTextBlock_lbl" xml:lang="en-US">Schedule of operating lease costs</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DefinedContributionPlanDisclosuresTableTextBlock" xlink:label="us-gaap_DefinedContributionPlanDisclosuresTableTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DefinedContributionPlanDisclosuresTableTextBlock" xlink:to="us-gaap_DefinedContributionPlanDisclosuresTableTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DefinedContributionPlanDisclosuresTableTextBlock_lbl" xml:lang="en-US">Schedule of contributions under the plan</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock" xlink:label="avxl_ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock" xlink:to="avxl_ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock_lbl" xml:lang="en-US">Schedule of share purchase warrants outstanding</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfStockOptionsRollForwardTableTextBlock" xlink:label="us-gaap_ScheduleOfStockOptionsRollForwardTableTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfStockOptionsRollForwardTableTextBlock" xlink:to="us-gaap_ScheduleOfStockOptionsRollForwardTableTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfStockOptionsRollForwardTableTextBlock_lbl" xml:lang="en-US">Schedule of stock option activity</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock" xlink:label="us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock" xlink:to="us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_lbl" xml:lang="en-US">Schedule of summarizes information about stock options</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock" xlink:label="us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock" xlink:to="us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_lbl" xml:lang="en-US">Schedule of general and administrative expenses and research and development expenses</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock" xlink:label="avxl_ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock" xlink:to="avxl_ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock_lbl" xml:lang="en-US">Schedule of weighted average assumptions for fair value of each option award</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock" xlink:label="us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock" xlink:to="us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock_lbl" xml:lang="en-US">Schedule of loss before income taxes</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock" xlink:label="us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock" xlink:to="us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_lbl" xml:lang="en-US">Schedule of components of net deferred income tax assets</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock" xlink:label="us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock" xlink:to="us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_lbl" xml:lang="en-US">Schedule of reconciliation of income tax expense</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashFDICInsuredAmount" xlink:label="us-gaap_CashFDICInsuredAmount" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashFDICInsuredAmount" xlink:to="us-gaap_CashFDICInsuredAmount_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CashFDICInsuredAmount_lbl" xml:lang="en-US">Federal deposit insurance corporation</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:label="us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:to="us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_lbl" xml:lang="en-US">Loss per share for potentially dilutive common shares</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_AccruedClinicalSiteAndPatientVisitsCosts" xlink:label="avxl_AccruedClinicalSiteAndPatientVisitsCosts" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_AccruedClinicalSiteAndPatientVisitsCosts" xlink:to="avxl_AccruedClinicalSiteAndPatientVisitsCosts_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_AccruedClinicalSiteAndPatientVisitsCosts_lbl" xml:lang="en-US">Accrued clinical site and patient visits costs</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccruedBonusesCurrent" xlink:label="us-gaap_AccruedBonusesCurrent" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccruedBonusesCurrent" xlink:to="us-gaap_AccruedBonusesCurrent_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccruedBonusesCurrent_lbl" xml:lang="en-US">Accrued compensation and benefits</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_FixedContractAccruals" xlink:label="avxl_FixedContractAccruals" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_FixedContractAccruals" xlink:to="avxl_FixedContractAccruals_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_FixedContractAccruals_lbl" xml:lang="en-US">Fixed contract accruals</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_MilestoneBasedContractAccruals" xlink:label="avxl_MilestoneBasedContractAccruals" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_MilestoneBasedContractAccruals" xlink:to="avxl_MilestoneBasedContractAccruals_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_MilestoneBasedContractAccruals_lbl" xml:lang="en-US">Milestone based contract accruals</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherAccruedLiabilitiesCurrent" xlink:label="us-gaap_OtherAccruedLiabilitiesCurrent" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OtherAccruedLiabilitiesCurrent" xlink:to="us-gaap_OtherAccruedLiabilitiesCurrent_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OtherAccruedLiabilitiesCurrent_lbl" xml:lang="en-US">All other accrued liabilities</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccruedLiabilitiesCurrent" xlink:to="us-gaap_AccruedLiabilitiesCurrent_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_AccruedLiabilitiesCurrent_2_lbl" xml:lang="en-US">Total accrued liabilities</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable" xlink:label="us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable" xlink:to="us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_lbl" xml:lang="en-US">Schedule of Defined Benefit Plans Disclosures [Table]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems" xlink:label="us-gaap_DefinedBenefitPlanDisclosureLineItems" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DefinedBenefitPlanDisclosureLineItems" xlink:to="us-gaap_DefinedBenefitPlanDisclosureLineItems_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DefinedBenefitPlanDisclosureLineItems_lbl" xml:lang="en-US">Defined Benefit Plan Disclosure [Line Items]</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_GrantIncome" xlink:label="avxl_GrantIncome" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_GrantIncome" xlink:to="avxl_GrantIncome_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="avxl_GrantIncome_lbl" xml:lang="en-US">Grant income</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned" xlink:label="us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned" xlink:to="us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_lbl" xml:lang="en-US">Research and development incentive income</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_NonOperatingIncomeFromGrant" xlink:label="avxl_NonOperatingIncomeFromGrant" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_NonOperatingIncomeFromGrant" xlink:to="avxl_NonOperatingIncomeFromGrant_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_NonOperatingIncomeFromGrant_lbl" xml:lang="en-US">Non operating income from grant</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DeferredGrantIncome1" xlink:label="avxl_DeferredGrantIncome1" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_DeferredGrantIncome1" xlink:to="avxl_DeferredGrantIncome1_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_DeferredGrantIncome1_lbl" xml:lang="en-US">Deferred grant income</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherReceivables" xlink:label="us-gaap_OtherReceivables" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OtherReceivables" xlink:to="us-gaap_OtherReceivables_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_OtherReceivables_lbl" xml:lang="en-US">Incentive and tax receivables</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction" xlink:label="us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction" xlink:to="us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_lbl" xml:lang="en-US">Number of common stock sold</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SaleOfStockPricePerShare" xlink:label="us-gaap_SaleOfStockPricePerShare" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SaleOfStockPricePerShare" xlink:to="us-gaap_SaleOfStockPricePerShare_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SaleOfStockPricePerShare_lbl" xml:lang="en-US">Sale of stock, per share</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SaleOfStockConsiderationReceivedOnTransaction" xlink:label="us-gaap_SaleOfStockConsiderationReceivedOnTransaction" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SaleOfStockConsiderationReceivedOnTransaction" xlink:to="us-gaap_SaleOfStockConsiderationReceivedOnTransaction_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SaleOfStockConsiderationReceivedOnTransaction_lbl" xml:lang="en-US">Gross proceeds from sale of stock</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromIssuanceInitialPublicOffering" xlink:label="us-gaap_ProceedsFromIssuanceInitialPublicOffering" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ProceedsFromIssuanceInitialPublicOffering" xlink:to="us-gaap_ProceedsFromIssuanceInitialPublicOffering_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ProceedsFromIssuanceInitialPublicOffering_lbl" xml:lang="en-US">Net proceed</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PercentageOfGrossProceedsFromSales" xlink:label="avxl_PercentageOfGrossProceedsFromSales" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_PercentageOfGrossProceedsFromSales" xlink:to="avxl_PercentageOfGrossProceedsFromSales_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_PercentageOfGrossProceedsFromSales_lbl" xml:lang="en-US">Percentage of gross proceeds from sales</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SaleOfStockConsiderationReceivedPerTransaction" xlink:label="us-gaap_SaleOfStockConsiderationReceivedPerTransaction" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SaleOfStockConsiderationReceivedPerTransaction" xlink:to="us-gaap_SaleOfStockConsiderationReceivedPerTransaction_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SaleOfStockConsiderationReceivedPerTransaction_lbl" xml:lang="en-US">Number of common stock sold, value</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SoldForGrossProceedsAmount" xlink:label="avxl_SoldForGrossProceedsAmount" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_SoldForGrossProceedsAmount" xlink:to="avxl_SoldForGrossProceedsAmount_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_SoldForGrossProceedsAmount_lbl" xml:lang="en-US">Sold for gross proceeds amount</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SalesOfAgreementAmount" xlink:label="avxl_SalesOfAgreementAmount" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_SalesOfAgreementAmount" xlink:to="avxl_SalesOfAgreementAmount_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_SalesOfAgreementAmount_lbl" xml:lang="en-US">Sales of agreement amount</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ValueOfSharesObligatedToPurchase" xlink:label="avxl_ValueOfSharesObligatedToPurchase" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_ValueOfSharesObligatedToPurchase" xlink:to="avxl_ValueOfSharesObligatedToPurchase_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_ValueOfSharesObligatedToPurchase_lbl" xml:lang="en-US">Value of shares obligated to purchase</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:label="us-gaap_StockIssuedDuringPeriodSharesNewIssues" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:to="us-gaap_StockIssuedDuringPeriodSharesNewIssues_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StockIssuedDuringPeriodSharesNewIssues_lbl" xml:lang="en-US">Number of shares issued, shares</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_NumberOfSharesObligatedToPurchaseProrataBasic" xlink:label="avxl_NumberOfSharesObligatedToPurchaseProrataBasic" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_NumberOfSharesObligatedToPurchaseProrataBasic" xlink:to="avxl_NumberOfSharesObligatedToPurchaseProrataBasic_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_NumberOfSharesObligatedToPurchaseProrataBasic_lbl" xml:lang="en-US">Pro rata basic number of shares obligated to purchase</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromIssuanceOrSaleOfEquity" xlink:label="us-gaap_ProceedsFromIssuanceOrSaleOfEquity" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ProceedsFromIssuanceOrSaleOfEquity" xlink:to="us-gaap_ProceedsFromIssuanceOrSaleOfEquity_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ProceedsFromIssuanceOrSaleOfEquity_lbl" xml:lang="en-US">Proceeds from issuance or sale of equity</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_FairValueOfInitialCommitment" xlink:label="avxl_FairValueOfInitialCommitment" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_FairValueOfInitialCommitment" xlink:to="avxl_FairValueOfInitialCommitment_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_FairValueOfInitialCommitment_lbl" xml:lang="en-US">Fair value of the initial commitment</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_IncurredExpenses" xlink:label="avxl_IncurredExpenses" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_IncurredExpenses" xlink:to="avxl_IncurredExpenses_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_IncurredExpenses_lbl" xml:lang="en-US">Incurred expenses</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues" xlink:label="us-gaap_StockIssuedDuringPeriodValueNewIssues" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockIssuedDuringPeriodValueNewIssues" xlink:to="us-gaap_StockIssuedDuringPeriodValueNewIssues_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StockIssuedDuringPeriodValueNewIssues_lbl" xml:lang="en-US">Number of shares issued, value</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockIssuedDuringPeriodValueOther" xlink:label="us-gaap_StockIssuedDuringPeriodValueOther" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockIssuedDuringPeriodValueOther" xlink:to="us-gaap_StockIssuedDuringPeriodValueOther_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StockIssuedDuringPeriodValueOther_lbl" xml:lang="en-US">Amount of shares remain available</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseCost" xlink:label="us-gaap_OperatingLeaseCost" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingLeaseCost" xlink:to="us-gaap_OperatingLeaseCost_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingLeaseCost_lbl" xml:lang="en-US">Operating lease costs</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PensionContributions" xlink:label="us-gaap_PensionContributions" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PensionContributions" xlink:to="us-gaap_PensionContributions_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PensionContributions_lbl" xml:lang="en-US">Contributions to 401(k) plan</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:to="us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_lbl" xml:lang="en-US">Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_lbl" xml:lang="en-US">Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_lbl" xml:lang="en-US">Number of warrants outstanding</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_lbl" xml:lang="en-US">Exercise Price</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_WarrantsAndRightsOutstandingMaturityDate" xlink:label="us-gaap_WarrantsAndRightsOutstandingMaturityDate" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_WarrantsAndRightsOutstandingMaturityDate" xlink:to="us-gaap_WarrantsAndRightsOutstandingMaturityDate_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_WarrantsAndRightsOutstandingMaturityDate_lbl" xml:lang="en-US">Expiry Date</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OffsettingAssetsTable" xlink:label="us-gaap_OffsettingAssetsTable" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OffsettingAssetsTable" xlink:to="us-gaap_OffsettingAssetsTable_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OffsettingAssetsTable_lbl" xml:lang="en-US">Offsetting Assets [Table]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OffsettingAssetsLineItems" xlink:label="us-gaap_OffsettingAssetsLineItems" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OffsettingAssetsLineItems" xlink:to="us-gaap_OffsettingAssetsLineItems_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OffsettingAssetsLineItems_lbl" xml:lang="en-US">Offsetting Assets [Line Items]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_lbl" xml:lang="en-US">Number of options, Outstanding beginning balance</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_lbl" xml:lang="en-US">Weighted average exercise price, Outstanding beginning balance</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_lbl" xml:lang="en-US">Weighted average grant date fair value, Outstanding beginning balance</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_lbl" xml:lang="en-US">Aggregate intrinsic value, Outstanding beginning balance</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_lbl" xml:lang="en-US">Number of options, Granted</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" xlink:label="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_lbl" xml:lang="en-US">Weighted average exercise price, Granted</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_lbl" xml:lang="en-US">Weighted average grant date fair value, Granted</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_lbl" xml:lang="en-US">Number of options, Forfeited</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice" xlink:label="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_lbl" xml:lang="en-US">Weighted average exercise price, Forfeited</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice" xlink:label="avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice" xlink:to="avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice_lbl" xml:lang="en-US">Weighted average grant date fair value, Forfeited</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:to="us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_lbl" xml:lang="en-US">Number of options, Exercised</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" xlink:label="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_lbl" xml:lang="en-US">Weighted average exercise price, Exercised</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice" xlink:label="avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice" xlink:to="avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice_lbl" xml:lang="en-US">Weighted average grant date fair value, Exercised</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_lbl" xml:lang="en-US">Aggregate intrinsic value, Exercised</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_2_lbl" xml:lang="en-US">Number of options, Outstanding ending balance</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_2_lbl" xml:lang="en-US">Weighted average exercise price, Outstanding ending balance</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_2_lbl" xml:lang="en-US">Weighted average grant date fair value, Outstanding ending balance</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_2_lbl" xml:lang="en-US">Aggregate intrinsic value, Outstanding ending balance</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_lbl" xml:lang="en-US">Number of options, Exercisable</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_lbl" xml:lang="en-US">Weighted average exercise price, Exercisable</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:to="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue_lbl" xml:lang="en-US">Weighted average grant date fair value, Exercisable</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1" xlink:to="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_lbl" xml:lang="en-US">Aggregate intrinsic value, Exercisable</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit" xlink:label="us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit" xlink:to="us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_lbl" xml:lang="en-US">Range of exercise prices, Lower range limit</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit" xlink:label="us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit" xlink:to="us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_lbl" xml:lang="en-US">Range of exercise prices, Upper range limit</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_3_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_3_lbl" xml:lang="en-US">Number of outstanding options</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:to="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_lbl" xml:lang="en-US">Weighted average remaining contractual life</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_3_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_3_lbl" xml:lang="en-US">Weighted average exercise price</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" xlink:to="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_lbl" xml:lang="en-US">Number of vested options</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_lbl" xml:lang="en-US">Weighted average exercise price options vested</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LossContingenciesTable" xlink:label="us-gaap_LossContingenciesTable" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LossContingenciesTable" xlink:to="us-gaap_LossContingenciesTable_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LossContingenciesTable_lbl" xml:lang="en-US">Loss Contingencies [Table]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LossContingenciesLineItems" xlink:label="us-gaap_LossContingenciesLineItems" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LossContingenciesLineItems" xlink:to="us-gaap_LossContingenciesLineItems_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LossContingenciesLineItems_lbl" xml:lang="en-US">Loss Contingencies [Line Items]</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensation" xlink:to="us-gaap_ShareBasedCompensation_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_ShareBasedCompensation_2_lbl" xml:lang="en-US">Total share based compensation</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_lbl" xml:lang="en-US">Risk-free interest rate</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:to="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_lbl" xml:lang="en-US">Expected life of options (years)</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_lbl" xml:lang="en-US">Annualized volatility</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_lbl" xml:lang="en-US">Dividend rate</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1" xlink:label="us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1" xlink:to="us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_lbl" xml:lang="en-US">Operating lease term</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ClassOfWarrantOrRightOutstanding" xlink:label="us-gaap_ClassOfWarrantOrRightOutstanding" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ClassOfWarrantOrRightOutstanding" xlink:to="us-gaap_ClassOfWarrantOrRightOutstanding_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ClassOfWarrantOrRightOutstanding_lbl" xml:lang="en-US">Warrants outstanding</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_WarrantsOutstandingWeightedAverageExercise" xlink:label="avxl_WarrantsOutstandingWeightedAverageExercise" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_WarrantsOutstandingWeightedAverageExercise" xlink:to="avxl_WarrantsOutstandingWeightedAverageExercise_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_WarrantsOutstandingWeightedAverageExercise_lbl" xml:lang="en-US">Warrants outstanding weighted average exercise price</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance" xlink:label="us-gaap_CommonStockCapitalSharesReservedForFutureIssuance" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockCapitalSharesReservedForFutureIssuance" xlink:to="us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_lbl" xml:lang="en-US">Maximum number of common shares reserved for future issuance</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_lbl" xml:lang="en-US">Additional shares of common stock available for issuance</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod_lbl" xml:lang="en-US">Option granted</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionIssued" xlink:label="avxl_OptionIssued" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_OptionIssued" xlink:to="avxl_OptionIssued_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_OptionIssued_lbl" xml:lang="en-US">Option issued</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_lbl" xml:lang="en-US">Option available issue</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_lbl" xml:lang="en-US">Weighted average grant date fair value of options vested</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:to="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_2_lbl" xml:lang="en-US">Weighted average contractual life of options outstanding</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2" xlink:label="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2" xlink:to="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_lbl" xml:lang="en-US">Options exercisable</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AllocatedShareBasedCompensationExpense" xlink:label="us-gaap_AllocatedShareBasedCompensationExpense" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AllocatedShareBasedCompensationExpense" xlink:to="us-gaap_AllocatedShareBasedCompensationExpense_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_AllocatedShareBasedCompensationExpense_lbl" xml:lang="en-US">Share based compensation</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions" xlink:label="us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions" xlink:to="us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_lbl" xml:lang="en-US">Remaining stock based compensation</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic" xlink:label="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic" xlink:to="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_lbl" xml:lang="en-US">United States</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign" xlink:label="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign" xlink:to="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_lbl" xml:lang="en-US">Foreign</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:to="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_2_lbl" xml:lang="en-US">Total</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwards" xlink:label="us-gaap_DeferredTaxAssetsOperatingLossCarryforwards" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredTaxAssetsOperatingLossCarryforwards" xlink:to="us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_lbl" xml:lang="en-US">Net operating loss carryforwards</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment" xlink:label="us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment" xlink:to="us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment_lbl" xml:lang="en-US">Research and development tax credit carryforwards</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" xlink:label="us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" xlink:to="us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_lbl" xml:lang="en-US">Stock-based compensation</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DeferredTaxAssetsResearchAndDevelopmentCapitalization" xlink:label="avxl_DeferredTaxAssetsResearchAndDevelopmentCapitalization" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_DeferredTaxAssetsResearchAndDevelopmentCapitalization" xlink:to="avxl_DeferredTaxAssetsResearchAndDevelopmentCapitalization_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_DeferredTaxAssetsResearchAndDevelopmentCapitalization_lbl" xml:lang="en-US">Research and development capitalization</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DeferredTaxAssetsUnpaidCharges" xlink:label="avxl_DeferredTaxAssetsUnpaidCharges" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_DeferredTaxAssetsUnpaidCharges" xlink:to="avxl_DeferredTaxAssetsUnpaidCharges_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_DeferredTaxAssetsUnpaidCharges_lbl" xml:lang="en-US">Unpaid charges</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets" xlink:label="us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets" xlink:to="us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets_lbl" xml:lang="en-US">Intangible asset costs</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsUnrealizedCurrencyLosses" xlink:label="us-gaap_DeferredTaxAssetsUnrealizedCurrencyLosses" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredTaxAssetsUnrealizedCurrencyLosses" xlink:to="us-gaap_DeferredTaxAssetsUnrealizedCurrencyLosses_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DeferredTaxAssetsUnrealizedCurrencyLosses_lbl" xml:lang="en-US">Foreign exchange and other</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsValuationAllowance" xlink:label="us-gaap_DeferredTaxAssetsValuationAllowance" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredTaxAssetsValuationAllowance" xlink:to="us-gaap_DeferredTaxAssetsValuationAllowance_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_DeferredTaxAssetsValuationAllowance_lbl" xml:lang="en-US">Valuation allowance of deferred tax assets</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsNet" xlink:label="us-gaap_DeferredTaxAssetsNet" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredTaxAssetsNet" xlink:to="us-gaap_DeferredTaxAssetsNet_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DeferredTaxAssetsNet_lbl" xml:lang="en-US">Net deferred tax assets</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate" xlink:label="us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate" xlink:to="us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_lbl" xml:lang="en-US">Income tax benefit at statutory federal rate</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential" xlink:label="us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential" xlink:to="us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_lbl" xml:lang="en-US">Foreign income taxed at other rates</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PermanentDifferencesRelatingToStockBasedCompensation" xlink:label="avxl_PermanentDifferencesRelatingToStockBasedCompensation" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_PermanentDifferencesRelatingToStockBasedCompensation" xlink:to="avxl_PermanentDifferencesRelatingToStockBasedCompensation_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_PermanentDifferencesRelatingToStockBasedCompensation_lbl" xml:lang="en-US">Permanent differences relating to stock based compensation</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationGiltiAmount" xlink:label="us-gaap_EffectiveIncomeTaxRateReconciliationGiltiAmount" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_EffectiveIncomeTaxRateReconciliationGiltiAmount" xlink:to="us-gaap_EffectiveIncomeTaxRateReconciliationGiltiAmount_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_EffectiveIncomeTaxRateReconciliationGiltiAmount_lbl" xml:lang="en-US">Permanent differences relating to GILTI inclusion</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PermanentDifferencesRelatingToSection162m" xlink:label="avxl_PermanentDifferencesRelatingToSection162m" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_PermanentDifferencesRelatingToSection162m" xlink:to="avxl_PermanentDifferencesRelatingToSection162m_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_PermanentDifferencesRelatingToSection162m_lbl" xml:lang="en-US">Permanent differences relating to Section 162(m)</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationOtherAdjustments" xlink:label="us-gaap_IncomeTaxReconciliationOtherAdjustments" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxReconciliationOtherAdjustments" xlink:to="us-gaap_IncomeTaxReconciliationOtherAdjustments_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeTaxReconciliationOtherAdjustments_lbl" xml:lang="en-US">Other permanent differences</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_AdjustmentToTaxAssetsBasedOnSection382" xlink:label="avxl_AdjustmentToTaxAssetsBasedOnSection382" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_AdjustmentToTaxAssetsBasedOnSection382" xlink:to="avxl_AdjustmentToTaxAssetsBasedOnSection382_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_AdjustmentToTaxAssetsBasedOnSection382_lbl" xml:lang="en-US">Adjustment to tax assets based on Section 382</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet" xlink:label="avxl_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet" xlink:to="avxl_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet_lbl" xml:lang="en-US">Research and development credits, net</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes" xlink:label="us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes" xlink:to="us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes_lbl" xml:lang="en-US">State and local taxes</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationPriorYearIncomeTaxes" xlink:label="us-gaap_IncomeTaxReconciliationPriorYearIncomeTaxes" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxReconciliationPriorYearIncomeTaxes" xlink:to="us-gaap_IncomeTaxReconciliationPriorYearIncomeTaxes_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeTaxReconciliationPriorYearIncomeTaxes_lbl" xml:lang="en-US">Adjustment to true up to prior years' tax provision</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate" xlink:label="us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate" xlink:to="us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate_lbl" xml:lang="en-US">Effect of change in statutory tax rates</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_TaxesExcludingIncomeAndExciseTaxes" xlink:label="us-gaap_TaxesExcludingIncomeAndExciseTaxes" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_TaxesExcludingIncomeAndExciseTaxes" xlink:to="us-gaap_TaxesExcludingIncomeAndExciseTaxes_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_TaxesExcludingIncomeAndExciseTaxes_lbl" xml:lang="en-US">State minimum and excise taxes</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance" xlink:label="us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance" xlink:to="us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_lbl" xml:lang="en-US">Change in valuation allowances</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit" xlink:label="us-gaap_DeferredIncomeTaxExpenseBenefit" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredIncomeTaxExpenseBenefit" xlink:to="us-gaap_DeferredIncomeTaxExpenseBenefit_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DeferredIncomeTaxExpenseBenefit_lbl" xml:lang="en-US">Income tax expense</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLossCarryforwardsTable" xlink:label="us-gaap_OperatingLossCarryforwardsTable" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingLossCarryforwardsTable" xlink:to="us-gaap_OperatingLossCarryforwardsTable_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingLossCarryforwardsTable_lbl" xml:lang="en-US">Operating Loss Carryforwards [Table]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLossCarryforwardsLineItems" xlink:label="us-gaap_OperatingLossCarryforwardsLineItems" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingLossCarryforwardsLineItems" xlink:to="us-gaap_OperatingLossCarryforwardsLineItems_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingLossCarryforwardsLineItems_lbl" xml:lang="en-US">Operating Loss Carryforwards [Line Items]</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLossCarryforwards" xlink:label="us-gaap_OperatingLossCarryforwards" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingLossCarryforwards" xlink:to="us-gaap_OperatingLossCarryforwards_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingLossCarryforwards_lbl" xml:lang="en-US">Operating loss carryforwards</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OperatingLossCarryforwardsDescription" xlink:label="avxl_OperatingLossCarryforwardsDescription" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_OperatingLossCarryforwardsDescription" xlink:to="avxl_OperatingLossCarryforwardsDescription_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_OperatingLossCarryforwardsDescription_lbl" xml:lang="en-US">Operating loss carryforwards description</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OperatingLossCarryForwardsExpirationYear" xlink:label="avxl_OperatingLossCarryForwardsExpirationYear" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_OperatingLossCarryForwardsExpirationYear" xlink:to="avxl_OperatingLossCarryForwardsExpirationYear_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_OperatingLossCarryForwardsExpirationYear_lbl" xml:lang="en-US">Operating loss carry forwards expiration year</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment" xlink:label="us-gaap_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment" xlink:to="us-gaap_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment_lbl" xml:lang="en-US">Research and Development tax credits</link:label>
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ResearchAndDevelopmentTaxCreditsYear" xlink:label="avxl_ResearchAndDevelopmentTaxCreditsYear" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_ResearchAndDevelopmentTaxCreditsYear" xlink:to="avxl_ResearchAndDevelopmentTaxCreditsYear_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_ResearchAndDevelopmentTaxCreditsYear_lbl" xml:lang="en-US">Research and development tax credits year</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsGross" xlink:label="us-gaap_DeferredTaxAssetsGross" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredTaxAssetsGross" xlink:to="us-gaap_DeferredTaxAssetsGross_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DeferredTaxAssetsGross_lbl" xml:lang="en-US">Gross deferred tax asset</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch" xlink:label="us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch" xlink:to="us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch_lbl" xml:lang="en-US">Research and development tax credit carryforwards</link:label>
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount" xlink:label="us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount" />
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount" xlink:to="us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount_lbl" xml:lang="en-US">Decrease in valuation allowance</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_Assets" xlink:to="us-gaap_Assets_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_Assets_2_lbl" xml:lang="en-US">Assets [Default Label]</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_Liabilities" xlink:to="us-gaap_Liabilities_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_Liabilities_2_lbl" xml:lang="en-US">Liabilities</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockholdersEquity" xlink:to="us-gaap_StockholdersEquity_4_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StockholdersEquity_4_lbl" xml:lang="en-US">Equity, Attributable to Parent</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LiabilitiesAndStockholdersEquity" xlink:to="us-gaap_LiabilitiesAndStockholdersEquity_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LiabilitiesAndStockholdersEquity_2_lbl" xml:lang="en-US">Liabilities and Equity</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingExpenses" xlink:to="us-gaap_OperatingExpenses_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingExpenses_2_lbl" xml:lang="en-US">Operating Expenses</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingIncomeLoss" xlink:to="us-gaap_OperatingIncomeLoss_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingIncomeLoss_2_lbl" xml:lang="en-US">Operating Income (Loss)</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_OtherFinancingExpense" xlink:to="avxl_OtherFinancingExpense_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_OtherFinancingExpense_2_lbl" xml:lang="en-US">OtherFinancingExpense</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NonoperatingIncomeExpense" xlink:to="us-gaap_NonoperatingIncomeExpense_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NonoperatingIncomeExpense_2_lbl" xml:lang="en-US">Nonoperating Income (Expense)</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CurrentIncomeTaxExpenseBenefit" xlink:to="us-gaap_CurrentIncomeTaxExpenseBenefit_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CurrentIncomeTaxExpenseBenefit_2_lbl" xml:lang="en-US">Current Income Tax Expense (Benefit)</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInIncomeTaxesReceivable" xlink:to="us-gaap_IncreaseDecreaseInIncomeTaxesReceivable_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncreaseDecreaseInIncomeTaxesReceivable_2_lbl" xml:lang="en-US">Increase (Decrease) in Income Taxes Receivable</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInPrepaidExpense" xlink:to="us-gaap_IncreaseDecreaseInPrepaidExpense_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncreaseDecreaseInPrepaidExpense_2_lbl" xml:lang="en-US">Increase (Decrease) in Prepaid Expense</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInAccountsPayable" xlink:to="us-gaap_IncreaseDecreaseInAccountsPayable_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncreaseDecreaseInAccountsPayable_2_lbl" xml:lang="en-US">Increase (Decrease) in Accounts Payable</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_DeferredGrantIncome" xlink:to="avxl_DeferredGrantIncome_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_DeferredGrantIncome_2_lbl" xml:lang="en-US">DeferredGrantIncome</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:to="us-gaap_NetCashProvidedByUsedInOperatingActivities_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivities_2_lbl" xml:lang="en-US">Net Cash Provided by (Used in) Operating Activities</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PaymentsOfStockIssuanceCosts" xlink:to="us-gaap_PaymentsOfStockIssuanceCosts_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PaymentsOfStockIssuanceCosts_2_lbl" xml:lang="en-US">Payments of Stock Issuance Costs</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:to="us-gaap_NetCashProvidedByUsedInFinancingActivities_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivities_2_lbl" xml:lang="en-US">Net Cash Provided by (Used in) Financing Activities</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:to="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect_2_lbl" xml:lang="en-US">Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Excluding Exchange Rate Effect</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:to="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_3_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_3_lbl" xml:lang="en-US">Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharesOutstanding" xlink:to="us-gaap_SharesOutstanding_3_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SharesOutstanding_3_lbl" xml:lang="en-US">Shares, Outstanding</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_LessRegisteredDirectOfferingShareIssueCosts" xlink:to="avxl_LessRegisteredDirectOfferingShareIssueCosts_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_LessRegisteredDirectOfferingShareIssueCosts_2_lbl" xml:lang="en-US">LessRegisteredDirectOfferingShareIssueCosts</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_AccuredLiabilitiesTextBlock" xlink:to="avxl_AccuredLiabilitiesTextBlock_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_AccuredLiabilitiesTextBlock_2_lbl" xml:lang="en-US">AccuredLiabilitiesTextBlock</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_OtherIncomeDisclosureTextBlock" xlink:to="avxl_OtherIncomeDisclosureTextBlock_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_OtherIncomeDisclosureTextBlock_2_lbl" xml:lang="en-US">OtherIncomeDisclosureTextBlock</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_EquityOfferingTextBlock" xlink:to="avxl_EquityOfferingTextBlock_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_EquityOfferingTextBlock_2_lbl" xml:lang="en-US">EquityOfferingTextBlock</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxPolicyTextBlock" xlink:to="us-gaap_IncomeTaxPolicyTextBlock_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeTaxPolicyTextBlock_2_lbl" xml:lang="en-US">Income Tax, Policy [Policy Text Block]</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="avxl_GrantIncome" xlink:to="avxl_GrantIncome_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="avxl_GrantIncome_2_lbl" xml:lang="en-US">GrantIncome</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned" xlink:to="us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_2_lbl" xml:lang="en-US">Research and Development Arrangement, Contract to Perform for Others, Compensation Earned</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OtherReceivables" xlink:to="us-gaap_OtherReceivables_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OtherReceivables_2_lbl" xml:lang="en-US">Other Receivables</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_3_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_3_lbl" xml:lang="en-US">Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_3_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_3_lbl" xml:lang="en-US">Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_2_lbl" xml:lang="en-US">Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:to="us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_2_lbl" xml:lang="en-US">Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AllocatedShareBasedCompensationExpense" xlink:to="us-gaap_AllocatedShareBasedCompensationExpense_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AllocatedShareBasedCompensationExpense_2_lbl" xml:lang="en-US">Share-Based Payment Arrangement, Expense</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" xlink:to="us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_2_lbl" xml:lang="en-US">Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredTaxAssetsValuationAllowance" xlink:to="us-gaap_DeferredTaxAssetsValuationAllowance_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DeferredTaxAssetsValuationAllowance_2_lbl" xml:lang="en-US">Deferred Tax Assets, Valuation Allowance</link:label>
      <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch" xlink:to="us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch_2_lbl" xlink:type="arc" />
      <link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch_2_lbl" xml:lang="en-US">Deferred Tax Assets, Tax Credit Carryforwards, Research</link:label>
    </link:labelLink>
</link:linkbase>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.PRE
<SEQUENCE>16
<FILENAME>avxl-20230930_pre.xml
<DESCRIPTION>XBRL PRESENTATION FILE
<TEXT>
<XBRL>
<?xml version="1.0" encoding="US-ASCII" standalone="no"?>
    <!-- Field: Doc-Info; Name: Generator; Value: GoXBRL; Version: 5.20c -->
    <!-- Field: Doc-Info; Name: VendorURI; Value: https://www.novaworks.com -->
    <!-- Field: Doc-Info; Name: Status; Value: 0x00000000 -->
<link:linkbase xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrli="http://www.xbrl.org/2003/instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
    <link:roleRef roleURI="http://anavex.com/role/Cover" xlink:href="avxl-20230930.xsd#Cover" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/BalanceSheets" xlink:href="avxl-20230930.xsd#BalanceSheets" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/BalanceSheetsParenthetical" xlink:href="avxl-20230930.xsd#BalanceSheetsParenthetical" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss" xlink:href="avxl-20230930.xsd#StatementsOfOperationsAndComprehensiveLoss" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/StatementsOfOperationsAndComprehensiveLossParenthetical" xlink:href="avxl-20230930.xsd#StatementsOfOperationsAndComprehensiveLossParenthetical" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/StatementsOfCashFlows" xlink:href="avxl-20230930.xsd#StatementsOfCashFlows" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/StatementsOfChangesInStockholdersEquity" xlink:href="avxl-20230930.xsd#StatementsOfChangesInStockholdersEquity" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/BusinessDescriptionAndBasisOfPresentation" xlink:href="avxl-20230930.xsd#BusinessDescriptionAndBasisOfPresentation" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/SummaryOfSignificantAccountingPolicies" xlink:href="avxl-20230930.xsd#SummaryOfSignificantAccountingPolicies" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/AccruedLiabilities" xlink:href="avxl-20230930.xsd#AccruedLiabilities" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/OtherIncome" xlink:href="avxl-20230930.xsd#OtherIncome" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/EquityOfferings" xlink:href="avxl-20230930.xsd#EquityOfferings" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingencies" xlink:href="avxl-20230930.xsd#CommitmentsAndContingencies" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxes" xlink:href="avxl-20230930.xsd#IncomeTaxes" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/SubsequentEvents" xlink:href="avxl-20230930.xsd#SubsequentEvents" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:href="avxl-20230930.xsd#SummaryOfSignificantAccountingPoliciesPolicies" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/AccruedLiabilitiesTables" xlink:href="avxl-20230930.xsd#AccruedLiabilitiesTables" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesTables" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesTables" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxesTables" xlink:href="avxl-20230930.xsd#IncomeTaxesTables" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/SummaryOfSignificantAccountingPoliciesDetailsNarrative" xlink:href="avxl-20230930.xsd#SummaryOfSignificantAccountingPoliciesDetailsNarrative" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/AccruedLiabilitiesDetails" xlink:href="avxl-20230930.xsd#AccruedLiabilitiesDetails" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/OtherIncomeDetailsNarrative" xlink:href="avxl-20230930.xsd#OtherIncomeDetailsNarrative" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/EquityOfferingsDetailsNarrative" xlink:href="avxl-20230930.xsd#EquityOfferingsDetailsNarrative" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails1" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails1" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails2" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails2" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails3" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails3" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails4" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails4" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails5" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails5" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetails6" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetails6" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative" xlink:href="avxl-20230930.xsd#CommitmentsAndContingenciesDetailsNarrative" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxesDetails" xlink:href="avxl-20230930.xsd#IncomeTaxesDetails" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxesDetails1" xlink:href="avxl-20230930.xsd#IncomeTaxesDetails1" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxesDetails2" xlink:href="avxl-20230930.xsd#IncomeTaxesDetails2" xlink:type="simple" />
    <link:roleRef roleURI="http://anavex.com/role/IncomeTaxesDetailsNarrative" xlink:href="avxl-20230930.xsd#IncomeTaxesDetailsNarrative" xlink:type="simple" />
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/Cover" xlink:title="00000001 - Document - Cover">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_CoverAbstract" xlink:label="loc_deiCoverAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentType" xlink:label="loc_deiDocumentType" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentType" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AmendmentFlag" xlink:label="loc_deiAmendmentFlag" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiAmendmentFlag" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AmendmentDescription" xlink:label="loc_deiAmendmentDescription" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiAmendmentDescription" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentRegistrationStatement" xlink:label="loc_deiDocumentRegistrationStatement" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentRegistrationStatement" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentAnnualReport" xlink:label="loc_deiDocumentAnnualReport" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentAnnualReport" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentQuarterlyReport" xlink:label="loc_deiDocumentQuarterlyReport" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentQuarterlyReport" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentTransitionReport" xlink:label="loc_deiDocumentTransitionReport" />
      <link:presentationArc order="60" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentTransitionReport" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentShellCompanyReport" xlink:label="loc_deiDocumentShellCompanyReport" />
      <link:presentationArc order="70" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentShellCompanyReport" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentShellCompanyEventDate" xlink:label="loc_deiDocumentShellCompanyEventDate" />
      <link:presentationArc order="80" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentShellCompanyEventDate" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentPeriodStartDate" xlink:label="loc_deiDocumentPeriodStartDate" />
      <link:presentationArc order="90" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentPeriodStartDate" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentPeriodEndDate" xlink:label="loc_deiDocumentPeriodEndDate" />
      <link:presentationArc order="100" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentPeriodEndDate" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentFiscalPeriodFocus" xlink:label="loc_deiDocumentFiscalPeriodFocus" />
      <link:presentationArc order="110" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentFiscalPeriodFocus" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentFiscalYearFocus" xlink:label="loc_deiDocumentFiscalYearFocus" />
      <link:presentationArc order="120" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentFiscalYearFocus" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_CurrentFiscalYearEndDate" xlink:label="loc_deiCurrentFiscalYearEndDate" />
      <link:presentationArc order="130" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiCurrentFiscalYearEndDate" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityFileNumber" xlink:label="loc_deiEntityFileNumber" />
      <link:presentationArc order="140" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityFileNumber" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityRegistrantName" xlink:label="loc_deiEntityRegistrantName" />
      <link:presentationArc order="150" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityRegistrantName" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityCentralIndexKey" xlink:label="loc_deiEntityCentralIndexKey" />
      <link:presentationArc order="160" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityCentralIndexKey" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityPrimarySicNumber" xlink:label="loc_deiEntityPrimarySicNumber" />
      <link:presentationArc order="170" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityPrimarySicNumber" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityTaxIdentificationNumber" xlink:label="loc_deiEntityTaxIdentificationNumber" />
      <link:presentationArc order="180" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityTaxIdentificationNumber" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityIncorporationStateCountryCode" xlink:label="loc_deiEntityIncorporationStateCountryCode" />
      <link:presentationArc order="190" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityIncorporationStateCountryCode" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressAddressLine1" xlink:label="loc_deiEntityAddressAddressLine1" />
      <link:presentationArc order="200" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityAddressAddressLine1" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressAddressLine2" xlink:label="loc_deiEntityAddressAddressLine2" />
      <link:presentationArc order="210" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityAddressAddressLine2" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressAddressLine3" xlink:label="loc_deiEntityAddressAddressLine3" />
      <link:presentationArc order="220" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityAddressAddressLine3" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressCityOrTown" xlink:label="loc_deiEntityAddressCityOrTown" />
      <link:presentationArc order="230" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityAddressCityOrTown" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressStateOrProvince" xlink:label="loc_deiEntityAddressStateOrProvince" />
      <link:presentationArc order="240" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityAddressStateOrProvince" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressCountry" xlink:label="loc_deiEntityAddressCountry" />
      <link:presentationArc order="250" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityAddressCountry" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressPostalZipCode" xlink:label="loc_deiEntityAddressPostalZipCode" />
      <link:presentationArc order="260" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityAddressPostalZipCode" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_CountryRegion" xlink:label="loc_deiCountryRegion" />
      <link:presentationArc order="270" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiCountryRegion" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_CityAreaCode" xlink:label="loc_deiCityAreaCode" />
      <link:presentationArc order="280" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiCityAreaCode" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_LocalPhoneNumber" xlink:label="loc_deiLocalPhoneNumber" />
      <link:presentationArc order="290" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiLocalPhoneNumber" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_Extension" xlink:label="loc_deiExtension" />
      <link:presentationArc order="300" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiExtension" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_WrittenCommunications" xlink:label="loc_deiWrittenCommunications" />
      <link:presentationArc order="310" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiWrittenCommunications" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_SolicitingMaterial" xlink:label="loc_deiSolicitingMaterial" />
      <link:presentationArc order="320" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiSolicitingMaterial" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_PreCommencementTenderOffer" xlink:label="loc_deiPreCommencementTenderOffer" />
      <link:presentationArc order="330" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiPreCommencementTenderOffer" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_PreCommencementIssuerTenderOffer" xlink:label="loc_deiPreCommencementIssuerTenderOffer" />
      <link:presentationArc order="340" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiPreCommencementIssuerTenderOffer" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_Security12bTitle" xlink:label="loc_deiSecurity12bTitle" />
      <link:presentationArc order="350" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiSecurity12bTitle" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_NoTradingSymbolFlag" xlink:label="loc_deiNoTradingSymbolFlag" />
      <link:presentationArc order="360" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiNoTradingSymbolFlag" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_TradingSymbol" xlink:label="loc_deiTradingSymbol" />
      <link:presentationArc order="370" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiTradingSymbol" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_SecurityExchangeName" xlink:label="loc_deiSecurityExchangeName" />
      <link:presentationArc order="380" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiSecurityExchangeName" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_Security12gTitle" xlink:label="loc_deiSecurity12gTitle" />
      <link:presentationArc order="390" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiSecurity12gTitle" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_SecurityReportingObligation" xlink:label="loc_deiSecurityReportingObligation" />
      <link:presentationArc order="400" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiSecurityReportingObligation" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AnnualInformationForm" xlink:label="loc_deiAnnualInformationForm" />
      <link:presentationArc order="410" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiAnnualInformationForm" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AuditedAnnualFinancialStatements" xlink:label="loc_deiAuditedAnnualFinancialStatements" />
      <link:presentationArc order="420" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiAuditedAnnualFinancialStatements" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityWellKnownSeasonedIssuer" xlink:label="loc_deiEntityWellKnownSeasonedIssuer" />
      <link:presentationArc order="430" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityWellKnownSeasonedIssuer" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityVoluntaryFilers" xlink:label="loc_deiEntityVoluntaryFilers" />
      <link:presentationArc order="440" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityVoluntaryFilers" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityCurrentReportingStatus" xlink:label="loc_deiEntityCurrentReportingStatus" />
      <link:presentationArc order="450" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityCurrentReportingStatus" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityInteractiveDataCurrent" xlink:label="loc_deiEntityInteractiveDataCurrent" />
      <link:presentationArc order="460" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityInteractiveDataCurrent" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityFilerCategory" xlink:label="loc_deiEntityFilerCategory" />
      <link:presentationArc order="470" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityFilerCategory" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntitySmallBusiness" xlink:label="loc_deiEntitySmallBusiness" />
      <link:presentationArc order="480" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntitySmallBusiness" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityEmergingGrowthCompany" xlink:label="loc_deiEntityEmergingGrowthCompany" />
      <link:presentationArc order="490" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityEmergingGrowthCompany" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityExTransitionPeriod" xlink:label="loc_deiEntityExTransitionPeriod" />
      <link:presentationArc order="500" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityExTransitionPeriod" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentAccountingStandard" xlink:label="loc_deiDocumentAccountingStandard" />
      <link:presentationArc order="510" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentAccountingStandard" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_OtherReportingStandardItemNumber" xlink:label="loc_deiOtherReportingStandardItemNumber" />
      <link:presentationArc order="520" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiOtherReportingStandardItemNumber" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityShellCompany" xlink:label="loc_deiEntityShellCompany" />
      <link:presentationArc order="530" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityShellCompany" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityPublicFloat" xlink:label="loc_deiEntityPublicFloat" />
      <link:presentationArc order="540" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityPublicFloat" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityBankruptcyProceedingsReportingCurrent" xlink:label="loc_deiEntityBankruptcyProceedingsReportingCurrent" />
      <link:presentationArc order="550" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityBankruptcyProceedingsReportingCurrent" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityCommonStockSharesOutstanding" xlink:label="loc_deiEntityCommonStockSharesOutstanding" />
      <link:presentationArc order="560" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityCommonStockSharesOutstanding" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentsIncorporatedByReferenceTextBlock" xlink:label="loc_deiDocumentsIncorporatedByReferenceTextBlock" />
      <link:presentationArc order="570" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentsIncorporatedByReferenceTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_IcfrAuditorAttestationFlag" xlink:label="loc_deiIcfrAuditorAttestationFlag" />
      <link:presentationArc order="580" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiIcfrAuditorAttestationFlag" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentFinStmtErrorCorrectionFlag" xlink:label="loc_deiDocumentFinStmtErrorCorrectionFlag" />
      <link:presentationArc order="590" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentFinStmtErrorCorrectionFlag" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AuditorName" xlink:label="loc_deiAuditorName" />
      <link:presentationArc order="600" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiAuditorName" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AuditorLocation" xlink:label="loc_deiAuditorLocation" />
      <link:presentationArc order="610" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiAuditorLocation" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AuditorFirmId" xlink:label="loc_deiAuditorFirmId" />
      <link:presentationArc order="620" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiAuditorFirmId" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/BalanceSheets" xlink:title="00000002 - Statement - Consolidated Balance Sheets">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaapStatementOfFinancialPositionAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AssetsAbstract" xlink:label="loc_us-gaapAssetsAbstract" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract" xlink:to="loc_us-gaapAssetsAbstract" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="loc_us-gaapAssetsCurrentAbstract" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsAbstract" xlink:to="loc_us-gaapAssetsCurrentAbstract" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaapCashAndCashEquivalentsAtCarryingValue" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsCurrentAbstract" xlink:to="loc_us-gaapCashAndCashEquivalentsAtCarryingValue" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxesReceivable" xlink:label="loc_us-gaapIncomeTaxesReceivable" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsCurrentAbstract" xlink:to="loc_us-gaapIncomeTaxesReceivable" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="loc_us-gaapPrepaidExpenseAndOtherAssetsCurrent" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsCurrentAbstract" xlink:to="loc_us-gaapPrepaidExpenseAndOtherAssetsCurrent" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_Assets" xlink:label="loc_us-gaapAssets" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsAbstract" xlink:to="loc_us-gaapAssets" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="loc_us-gaapLiabilitiesAndStockholdersEquityAbstract" />
      <link:presentationArc order="60" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract" xlink:to="loc_us-gaapLiabilitiesAndStockholdersEquityAbstract" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="loc_us-gaapLiabilitiesCurrentAbstract" />
      <link:presentationArc order="70" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLiabilitiesAndStockholdersEquityAbstract" xlink:to="loc_us-gaapLiabilitiesCurrentAbstract" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccountsPayableCurrent" xlink:label="loc_us-gaapAccountsPayableCurrent" />
      <link:presentationArc order="80" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLiabilitiesCurrentAbstract" xlink:to="loc_us-gaapAccountsPayableCurrent" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="loc_us-gaapAccruedLiabilitiesCurrent" />
      <link:presentationArc order="90" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLiabilitiesCurrentAbstract" xlink:to="loc_us-gaapAccruedLiabilitiesCurrent" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredRentCredit" xlink:label="loc_us-gaapDeferredRentCredit" />
      <link:presentationArc order="100" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLiabilitiesCurrentAbstract" xlink:to="loc_us-gaapDeferredRentCredit" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_Liabilities" xlink:label="loc_us-gaapLiabilities" />
      <link:presentationArc order="110" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLiabilitiesCurrentAbstract" xlink:to="loc_us-gaapLiabilities" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingencies" xlink:label="loc_us-gaapCommitmentsAndContingencies" />
      <link:presentationArc order="120" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLiabilitiesAndStockholdersEquityAbstract" xlink:to="loc_us-gaapCommitmentsAndContingencies" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PreferredStockValue" xlink:label="loc_us-gaapPreferredStockValue" />
      <link:presentationArc order="130" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLiabilitiesAndStockholdersEquityAbstract" xlink:to="loc_us-gaapPreferredStockValue" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockValue" xlink:label="loc_us-gaapCommonStockValue" />
      <link:presentationArc order="140" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract" xlink:to="loc_us-gaapCommonStockValue" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AdditionalPaidInCapitalCommonStock" xlink:label="loc_us-gaapAdditionalPaidInCapitalCommonStock" />
      <link:presentationArc order="150" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract" xlink:to="loc_us-gaapAdditionalPaidInCapitalCommonStock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaapRetainedEarningsAccumulatedDeficit" />
      <link:presentationArc order="160" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract" xlink:to="loc_us-gaapRetainedEarningsAccumulatedDeficit" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaapStockholdersEquity" />
      <link:presentationArc order="170" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract" xlink:to="loc_us-gaapStockholdersEquity" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="loc_us-gaapLiabilitiesAndStockholdersEquity" />
      <link:presentationArc order="180" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract" xlink:to="loc_us-gaapLiabilitiesAndStockholdersEquity" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/BalanceSheetsParenthetical" xlink:title="00000003 - Statement - Consolidated Balance Sheets (Parenthetical)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaapStatementOfFinancialPositionAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PreferredStockSharesAuthorized" xlink:label="loc_us-gaapPreferredStockSharesAuthorized" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract" xlink:to="loc_us-gaapPreferredStockSharesAuthorized" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PreferredStockParOrStatedValuePerShare" xlink:label="loc_us-gaapPreferredStockParOrStatedValuePerShare" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract" xlink:to="loc_us-gaapPreferredStockParOrStatedValuePerShare" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockSharesAuthorized" xlink:label="loc_us-gaapCommonStockSharesAuthorized" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract" xlink:to="loc_us-gaapCommonStockSharesAuthorized" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockParOrStatedValuePerShare" xlink:label="loc_us-gaapCommonStockParOrStatedValuePerShare" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract" xlink:to="loc_us-gaapCommonStockParOrStatedValuePerShare" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockSharesIssued" xlink:label="loc_us-gaapCommonStockSharesIssued" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract" xlink:to="loc_us-gaapCommonStockSharesIssued" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockSharesOutstanding" xlink:label="loc_us-gaapCommonStockSharesOutstanding" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract" xlink:to="loc_us-gaapCommonStockSharesOutstanding" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss" xlink:title="00000004 - Statement - Consolidated Statements of Operations and Comprehensive Loss">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeStatementAbstract" xlink:label="loc_us-gaapIncomeStatementAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingExpensesAbstract" xlink:label="loc_us-gaapOperatingExpensesAbstract" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementAbstract" xlink:to="loc_us-gaapOperatingExpensesAbstract" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_GeneralAndAdministrativeExpense" xlink:label="loc_us-gaapGeneralAndAdministrativeExpense" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingExpensesAbstract" xlink:to="loc_us-gaapGeneralAndAdministrativeExpense" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ResearchAndDevelopmentExpense" xlink:label="loc_us-gaapResearchAndDevelopmentExpense" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingExpensesAbstract" xlink:to="loc_us-gaapResearchAndDevelopmentExpense" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingExpenses" xlink:label="loc_us-gaapOperatingExpenses" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingExpensesAbstract" xlink:to="loc_us-gaapOperatingExpenses" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaapOperatingIncomeLoss" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingExpensesAbstract" xlink:to="loc_us-gaapOperatingIncomeLoss" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NonoperatingIncomeExpenseAbstract" xlink:label="loc_us-gaapNonoperatingIncomeExpenseAbstract" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementAbstract" xlink:to="loc_us-gaapNonoperatingIncomeExpenseAbstract" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_NonOperatingIncomeFromGrants" xlink:label="loc_avxlNonOperatingIncomeFromGrants" />
      <link:presentationArc order="60" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract" xlink:to="loc_avxlNonOperatingIncomeFromGrants" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ResearchAndDevelopmentIncentiveIncome" xlink:label="loc_avxlResearchAndDevelopmentIncentiveIncome" />
      <link:presentationArc order="70" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract" xlink:to="loc_avxlResearchAndDevelopmentIncentiveIncome" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InterestIncomeExpenseNet" xlink:label="loc_us-gaapInterestIncomeExpenseNet" />
      <link:presentationArc order="80" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract" xlink:to="loc_us-gaapInterestIncomeExpenseNet" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OtherFinancingExpense" xlink:label="loc_avxlOtherFinancingExpense" />
      <link:presentationArc order="90" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract" xlink:to="loc_avxlOtherFinancingExpense" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ForeignCurrencyTransactionGainLossBeforeTax" xlink:label="loc_us-gaapForeignCurrencyTransactionGainLossBeforeTax" />
      <link:presentationArc order="100" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract" xlink:to="loc_us-gaapForeignCurrencyTransactionGainLossBeforeTax" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NonoperatingIncomeExpense" xlink:label="loc_us-gaapNonoperatingIncomeExpense" />
      <link:presentationArc order="110" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract" xlink:to="loc_us-gaapNonoperatingIncomeExpense" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:label="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" />
      <link:presentationArc order="120" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract" xlink:to="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CurrentIncomeTaxExpenseBenefit" xlink:label="loc_us-gaapCurrentIncomeTaxExpenseBenefit" />
      <link:presentationArc order="130" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementAbstract" xlink:to="loc_us-gaapCurrentIncomeTaxExpenseBenefit" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaapNetIncomeLoss" />
      <link:presentationArc order="140" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementAbstract" xlink:to="loc_us-gaapNetIncomeLoss" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_EarningPerShareBasicAndDilutedAbstract" xlink:label="loc_avxlEarningPerShareBasicAndDilutedAbstract" />
      <link:presentationArc order="150" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementAbstract" xlink:to="loc_avxlEarningPerShareBasicAndDilutedAbstract" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="loc_us-gaapWeightedAverageNumberOfSharesOutstandingAbstract" />
      <link:presentationArc order="160" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementAbstract" xlink:to="loc_us-gaapWeightedAverageNumberOfSharesOutstandingAbstract" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/StatementsOfOperationsAndComprehensiveLossParenthetical" xlink:title="00000005 - Statement - Consolidated Statements of Operations and Comprehensive Loss (Parenthetical)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeStatementAbstract" xlink:label="loc_us-gaapIncomeStatementAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EarningsPerShareBasic" xlink:label="loc_us-gaapEarningsPerShareBasic" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementAbstract" xlink:to="loc_us-gaapEarningsPerShareBasic" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EarningsPerShareDiluted" xlink:label="loc_us-gaapEarningsPerShareDiluted" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementAbstract" xlink:to="loc_us-gaapEarningsPerShareDiluted" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="loc_us-gaapWeightedAverageNumberOfSharesOutstandingBasic" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementAbstract" xlink:to="loc_us-gaapWeightedAverageNumberOfSharesOutstandingBasic" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="loc_us-gaapWeightedAverageNumberOfDilutedSharesOutstanding" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementAbstract" xlink:to="loc_us-gaapWeightedAverageNumberOfDilutedSharesOutstanding" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/StatementsOfCashFlows" xlink:title="00000006 - Statement - Consolidated Statements of Cash Flows">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="loc_us-gaapStatementOfCashFlowsAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract" xlink:label="loc_us-gaapNetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfCashFlowsAbstract" xlink:to="loc_us-gaapNetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaapNetIncomeLoss" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract" xlink:to="loc_us-gaapNetIncomeLoss" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_us-gaapAdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract" xlink:to="loc_us-gaapAdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_NoncashFinancingRelatedCharges" xlink:label="loc_avxlNoncashFinancingRelatedCharges" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract" xlink:to="loc_avxlNoncashFinancingRelatedCharges" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaapShareBasedCompensation" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract" xlink:to="loc_us-gaapShareBasedCompensation" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract" xlink:to="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInIncomeTaxesReceivable" xlink:label="loc_us-gaapIncreaseDecreaseInIncomeTaxesReceivable" />
      <link:presentationArc order="60" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract" xlink:to="loc_us-gaapIncreaseDecreaseInIncomeTaxesReceivable" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInPrepaidExpense" xlink:label="loc_us-gaapIncreaseDecreaseInPrepaidExpense" />
      <link:presentationArc order="70" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract" xlink:to="loc_us-gaapIncreaseDecreaseInPrepaidExpense" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInAccountsPayable" xlink:label="loc_us-gaapIncreaseDecreaseInAccountsPayable" />
      <link:presentationArc order="80" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract" xlink:to="loc_us-gaapIncreaseDecreaseInAccountsPayable" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilities" xlink:label="loc_us-gaapIncreaseDecreaseInAccruedLiabilities" />
      <link:presentationArc order="90" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract" xlink:to="loc_us-gaapIncreaseDecreaseInAccruedLiabilities" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DeferredGrantIncome" xlink:label="loc_avxlDeferredGrantIncome" />
      <link:presentationArc order="100" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract" xlink:to="loc_avxlDeferredGrantIncome" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" />
      <link:presentationArc order="110" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract" xlink:to="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract" xlink:label="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract" />
      <link:presentationArc order="120" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfCashFlowsAbstract" xlink:to="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock" xlink:label="loc_us-gaapProceedsFromIssuanceOfCommonStock" />
      <link:presentationArc order="130" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract" xlink:to="loc_us-gaapProceedsFromIssuanceOfCommonStock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PaymentsOfStockIssuanceCosts" xlink:label="loc_us-gaapPaymentsOfStockIssuanceCosts" />
      <link:presentationArc order="140" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract" xlink:to="loc_us-gaapPaymentsOfStockIssuanceCosts" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromWarrantExercises" xlink:label="loc_us-gaapProceedsFromWarrantExercises" />
      <link:presentationArc order="150" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract" xlink:to="loc_us-gaapProceedsFromWarrantExercises" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromStockOptionsExercised" xlink:label="loc_us-gaapProceedsFromStockOptionsExercised" />
      <link:presentationArc order="160" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract" xlink:to="loc_us-gaapProceedsFromStockOptionsExercised" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" />
      <link:presentationArc order="170" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract" xlink:to="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:label="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" />
      <link:presentationArc order="180" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfCashFlowsAbstract" xlink:to="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" />
      <link:presentationArc order="190" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfCashFlowsAbstract" xlink:to="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_2" />
      <link:presentationArc order="200" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfCashFlowsAbstract" xlink:to="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="loc_us-gaapSupplementalCashFlowInformationAbstract" />
      <link:presentationArc order="210" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfCashFlowsAbstract" xlink:to="loc_us-gaapSupplementalCashFlowInformationAbstract" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CashPaidForStateAndLocalMinimumIncomeTaxes" xlink:label="loc_avxlCashPaidForStateAndLocalMinimumIncomeTaxes" />
      <link:presentationArc order="220" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapSupplementalCashFlowInformationAbstract" xlink:to="loc_avxlCashPaidForStateAndLocalMinimumIncomeTaxes" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/StatementsOfChangesInStockholdersEquity" xlink:title="00000007 - Statement - Consolidated Statements of Changes in Stockholders&apos; Equity">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="loc_us-gaapStatementOfStockholdersEquityAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfStockholdersEquityAbstract" xlink:to="loc_us-gaapStatementTable" order="100" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable" xlink:to="loc_us-gaapStatementLineItems" order="200" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaapStatementEquityComponentsAxis" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable" xlink:to="loc_us-gaapStatementEquityComponentsAxis" order="10" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaapEquityComponentDomain" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementEquityComponentsAxis" xlink:to="loc_us-gaapEquityComponentDomain" order="40" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaapCommonStockMember" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementEquityComponentsAxis" xlink:to="loc_us-gaapCommonStockMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="loc_us-gaapAdditionalPaidInCapitalMember" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementEquityComponentsAxis" xlink:to="loc_us-gaapAdditionalPaidInCapitalMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RetainedEarningsMember" xlink:label="loc_us-gaapRetainedEarningsMember" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementEquityComponentsAxis" xlink:to="loc_us-gaapRetainedEarningsMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaapStockholdersEquity" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStockholdersEquity" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharesOutstanding" xlink:label="loc_us-gaapSharesOutstanding" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapSharesOutstanding" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares" xlink:label="loc_avxlSharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares" xlink:label="loc_avxlSharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockRepurchasedDuringPeriodValue" xlink:label="loc_us-gaapStockRepurchasedDuringPeriodValue" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStockRepurchasedDuringPeriodValue" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockRepurchasedDuringPeriodShares" xlink:label="loc_us-gaapStockRepurchasedDuringPeriodShares" />
      <link:presentationArc order="60" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStockRepurchasedDuringPeriodShares" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CommitmentShares" xlink:label="loc_avxlCommitmentShares" />
      <link:presentationArc order="70" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlCommitmentShares" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CommitmentSharesShares" xlink:label="loc_avxlCommitmentSharesShares" />
      <link:presentationArc order="80" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlCommitmentSharesShares" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedUnderSalesAgreement" xlink:label="loc_avxlSharesIssuedUnderSalesAgreement" />
      <link:presentationArc order="90" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedUnderSalesAgreement" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedUnderSalesAgreementShares" xlink:label="loc_avxlSharesIssuedUnderSalesAgreementShares" />
      <link:presentationArc order="100" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedUnderSalesAgreementShares" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_LessSalesAgreementShareIssueCosts" xlink:label="loc_avxlLessSalesAgreementShareIssueCosts" />
      <link:presentationArc order="110" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlLessSalesAgreementShareIssueCosts" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPursuantToRegisteredDirectOffering" xlink:label="loc_avxlSharesIssuedPursuantToRegisteredDirectOffering" />
      <link:presentationArc order="120" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedPursuantToRegisteredDirectOffering" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPursuantToRegisteredDirectOfferingShares" xlink:label="loc_avxlSharesIssuedPursuantToRegisteredDirectOfferingShares" />
      <link:presentationArc order="130" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedPursuantToRegisteredDirectOfferingShares" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_LessRegisteredDirectOfferingShareIssueCosts" xlink:label="loc_avxlLessRegisteredDirectOfferingShareIssueCosts" />
      <link:presentationArc order="140" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlLessRegisteredDirectOfferingShareIssueCosts" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPursuantToExerciseOfStockOptions" xlink:label="loc_avxlSharesIssuedPursuantToExerciseOfStockOptions" />
      <link:presentationArc order="150" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedPursuantToExerciseOfStockOptions" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPursuantToExerciseOfStockOptionsShares" xlink:label="loc_avxlSharesIssuedPursuantToExerciseOfStockOptionsShares" />
      <link:presentationArc order="160" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedPursuantToExerciseOfStockOptionsShares" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPusuantToExerciseOfWarrants" xlink:label="loc_avxlSharesIssuedPusuantToExerciseOfWarrants" />
      <link:presentationArc order="170" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedPusuantToExerciseOfWarrants" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SharesIssuedPusuantToExerciseOfWarrantsShares" xlink:label="loc_avxlSharesIssuedPusuantToExerciseOfWarrantsShares" />
      <link:presentationArc order="180" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSharesIssuedPusuantToExerciseOfWarrantsShares" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:label="loc_us-gaapAdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" />
      <link:presentationArc order="190" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapAdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaapNetIncomeLoss" />
      <link:presentationArc order="200" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapNetIncomeLoss" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaapStockholdersEquity_2" />
      <link:presentationArc order="210" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStockholdersEquity_2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharesOutstanding" xlink:label="loc_us-gaapSharesOutstanding_2" />
      <link:presentationArc order="220" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapSharesOutstanding_2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/BusinessDescriptionAndBasisOfPresentation" xlink:title="00000008 - Disclosure - Business Description and Basis of Presentation">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock" xlink:label="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:to="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/SummaryOfSignificantAccountingPolicies" xlink:title="00000009 - Disclosure - Summary of Significant Accounting Policies">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaapAccountingPoliciesAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SignificantAccountingPoliciesTextBlock" xlink:label="loc_us-gaapSignificantAccountingPoliciesTextBlock" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapSignificantAccountingPoliciesTextBlock" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/AccruedLiabilities" xlink:title="00000010 - Disclosure - Accrued Liabilities">
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DisclosureAccruedLiabilitiesAbstract" xlink:label="loc_avxlDisclosureAccruedLiabilitiesAbstract" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_AccuredLiabilitiesTextBlock" xlink:label="loc_avxlAccuredLiabilitiesTextBlock" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_avxlDisclosureAccruedLiabilitiesAbstract" xlink:to="loc_avxlAccuredLiabilitiesTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/OtherIncome" xlink:title="00000011 - Disclosure - Other Income">
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DisclosureOtherIncomeAbstract" xlink:label="loc_avxlDisclosureOtherIncomeAbstract" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OtherIncomeDisclosureTextBlock" xlink:label="loc_avxlOtherIncomeDisclosureTextBlock" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_avxlDisclosureOtherIncomeAbstract" xlink:to="loc_avxlOtherIncomeDisclosureTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/EquityOfferings" xlink:title="00000012 - Disclosure - Equity Offerings">
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DisclosureEquityOfferingsAbstract" xlink:label="loc_avxlDisclosureEquityOfferingsAbstract" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_EquityOfferingTextBlock" xlink:label="loc_avxlEquityOfferingTextBlock" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_avxlDisclosureEquityOfferingsAbstract" xlink:to="loc_avxlEquityOfferingTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingencies" xlink:title="00000013 - Disclosure - Commitments and Contingencies">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsDisclosureTextBlock" xlink:label="loc_us-gaapCommitmentsDisclosureTextBlock" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapCommitmentsDisclosureTextBlock" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxes" xlink:title="00000014 - Disclosure - Income Taxes">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaapIncomeTaxDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxDisclosureTextBlock" xlink:label="loc_us-gaapIncomeTaxDisclosureTextBlock" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapIncomeTaxDisclosureTextBlock" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/SubsequentEvents" xlink:title="00000015 - Disclosure - Subsequent Events">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SubsequentEventsAbstract" xlink:label="loc_us-gaapSubsequentEventsAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SubsequentEventsTextBlock" xlink:label="loc_us-gaapSubsequentEventsTextBlock" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapSubsequentEventsAbstract" xlink:to="loc_us-gaapSubsequentEventsTextBlock" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:title="00000016 - Disclosure - Summary of Significant Accounting Policies (Policies)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaapAccountingPoliciesAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_UseOfEstimates" xlink:label="loc_us-gaapUseOfEstimates" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapUseOfEstimates" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ConsolidationPolicyTextBlock" xlink:label="loc_us-gaapConsolidationPolicyTextBlock" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapConsolidationPolicyTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashAndCashEquivalentsPolicyTextBlock" xlink:label="loc_us-gaapCashAndCashEquivalentsPolicyTextBlock" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapCashAndCashEquivalentsPolicyTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ResearchAndDevelopmentExpensePolicy" xlink:label="loc_us-gaapResearchAndDevelopmentExpensePolicy" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapResearchAndDevelopmentExpensePolicy" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RevenueRecognitionIncentives" xlink:label="loc_us-gaapRevenueRecognitionIncentives" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapRevenueRecognitionIncentives" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_LicenseFeesPolicyTextBlock" xlink:label="loc_avxlLicenseFeesPolicyTextBlock" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_avxlLicenseFeesPolicyTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EarningsPerSharePolicyTextBlock" xlink:label="loc_us-gaapEarningsPerSharePolicyTextBlock" />
      <link:presentationArc order="60" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapEarningsPerSharePolicyTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FairValueOfFinancialInstrumentsPolicy" xlink:label="loc_us-gaapFairValueOfFinancialInstrumentsPolicy" />
      <link:presentationArc order="70" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapFairValueOfFinancialInstrumentsPolicy" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock" xlink:label="loc_us-gaapForeignCurrencyTransactionsAndTranslationsPolicyTextBlock" />
      <link:presentationArc order="80" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapForeignCurrencyTransactionsAndTranslationsPolicyTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SegmentReportingPolicyPolicyTextBlock" xlink:label="loc_us-gaapSegmentReportingPolicyPolicyTextBlock" />
      <link:presentationArc order="90" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapSegmentReportingPolicyPolicyTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_GrantIncomePolicyTextBlock" xlink:label="loc_avxlGrantIncomePolicyTextBlock" />
      <link:presentationArc order="100" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_avxlGrantIncomePolicyTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxPolicyTextBlock" xlink:label="loc_us-gaapIncomeTaxPolicyTextBlock" />
      <link:presentationArc order="110" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapIncomeTaxPolicyTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationForfeituresPolicyTextBlock" xlink:label="loc_us-gaapShareBasedCompensationForfeituresPolicyTextBlock" />
      <link:presentationArc order="120" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapShareBasedCompensationForfeituresPolicyTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FairValueMeasurementPolicyPolicyTextBlock" xlink:label="loc_us-gaapFairValueMeasurementPolicyPolicyTextBlock" />
      <link:presentationArc order="130" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapFairValueMeasurementPolicyPolicyTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:label="loc_us-gaapNewAccountingPronouncementsPolicyPolicyTextBlock" />
      <link:presentationArc order="140" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapNewAccountingPronouncementsPolicyPolicyTextBlock" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/AccruedLiabilitiesTables" xlink:title="00000017 - Disclosure - Accrued Liabilities (Tables)">
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DisclosureAccruedLiabilitiesAbstract" xlink:label="loc_avxlDisclosureAccruedLiabilitiesAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock" xlink:label="loc_us-gaapScheduleOfAccruedLiabilitiesTableTextBlock" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_avxlDisclosureAccruedLiabilitiesAbstract" xlink:to="loc_us-gaapScheduleOfAccruedLiabilitiesTableTextBlock" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesTables" xlink:title="00000018 - Disclosure - Commitments and Contingencies (Tables)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LeaseCostTableTextBlock" xlink:label="loc_us-gaapLeaseCostTableTextBlock" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapLeaseCostTableTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DefinedContributionPlanDisclosuresTableTextBlock" xlink:label="loc_us-gaapDefinedContributionPlanDisclosuresTableTextBlock" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapDefinedContributionPlanDisclosuresTableTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock" xlink:label="loc_avxlScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_avxlScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfStockOptionsRollForwardTableTextBlock" xlink:label="loc_us-gaapScheduleOfStockOptionsRollForwardTableTextBlock" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapScheduleOfStockOptionsRollForwardTableTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock" xlink:label="loc_us-gaapScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock" xlink:label="loc_us-gaapScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock" xlink:label="loc_avxlScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock" />
      <link:presentationArc order="60" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_avxlScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxesTables" xlink:title="00000019 - Disclosure - Income Taxes (Tables)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaapIncomeTaxDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock" xlink:label="loc_us-gaapScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock" xlink:label="loc_us-gaapScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock" xlink:label="loc_us-gaapScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/SummaryOfSignificantAccountingPoliciesDetailsNarrative" xlink:title="00000020 - Disclosure - Summary of Significant Accounting Policies (Details Narrative)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaapAccountingPoliciesAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashFDICInsuredAmount" xlink:label="loc_us-gaapCashFDICInsuredAmount" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapCashFDICInsuredAmount" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:label="loc_us-gaapAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract" xlink:to="loc_us-gaapAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/AccruedLiabilitiesDetails" xlink:title="00000021 - Disclosure - Accrued Liabilities (Details)">
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DisclosureAccruedLiabilitiesAbstract" xlink:label="loc_avxlDisclosureAccruedLiabilitiesAbstract" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_AccruedClinicalSiteAndPatientVisitsCosts" xlink:label="loc_avxlAccruedClinicalSiteAndPatientVisitsCosts" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_avxlDisclosureAccruedLiabilitiesAbstract" xlink:to="loc_avxlAccruedClinicalSiteAndPatientVisitsCosts" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccruedBonusesCurrent" xlink:label="loc_us-gaapAccruedBonusesCurrent" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_avxlDisclosureAccruedLiabilitiesAbstract" xlink:to="loc_us-gaapAccruedBonusesCurrent" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_FixedContractAccruals" xlink:label="loc_avxlFixedContractAccruals" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_avxlDisclosureAccruedLiabilitiesAbstract" xlink:to="loc_avxlFixedContractAccruals" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_MilestoneBasedContractAccruals" xlink:label="loc_avxlMilestoneBasedContractAccruals" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_avxlDisclosureAccruedLiabilitiesAbstract" xlink:to="loc_avxlMilestoneBasedContractAccruals" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherAccruedLiabilitiesCurrent" xlink:label="loc_us-gaapOtherAccruedLiabilitiesCurrent" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_avxlDisclosureAccruedLiabilitiesAbstract" xlink:to="loc_us-gaapOtherAccruedLiabilitiesCurrent" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="loc_us-gaapAccruedLiabilitiesCurrent" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_avxlDisclosureAccruedLiabilitiesAbstract" xlink:to="loc_us-gaapAccruedLiabilitiesCurrent" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/OtherIncomeDetailsNarrative" xlink:title="00000022 - Disclosure - Other Income (Details Narrative)">
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DisclosureOtherIncomeAbstract" xlink:label="loc_avxlDisclosureOtherIncomeAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable" xlink:label="loc_us-gaapScheduleOfDefinedBenefitPlansDisclosuresTable" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_avxlDisclosureOtherIncomeAbstract" xlink:to="loc_us-gaapScheduleOfDefinedBenefitPlansDisclosuresTable" order="100" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems" xlink:label="loc_us-gaapDefinedBenefitPlanDisclosureLineItems" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapScheduleOfDefinedBenefitPlansDisclosuresTable" xlink:to="loc_us-gaapDefinedBenefitPlanDisclosureLineItems" order="200" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="loc_us-gaapRelatedPartyTransactionsByRelatedPartyAxis" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapScheduleOfDefinedBenefitPlansDisclosuresTable" xlink:to="loc_us-gaapRelatedPartyTransactionsByRelatedPartyAxis" order="10" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_us-gaapRelatedPartyDomain" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyTransactionsByRelatedPartyAxis" xlink:to="loc_us-gaapRelatedPartyDomain" order="0" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_MichaelJFoxFoundationMember" xlink:label="loc_avxlMichaelJFoxFoundationMember" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyDomain" xlink:to="loc_avxlMichaelJFoxFoundationMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2023/elts/srt-2023.xsd#srt_CurrencyAxis" xlink:label="loc_srtCurrencyAxis" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapScheduleOfDefinedBenefitPlansDisclosuresTable" xlink:to="loc_srtCurrencyAxis" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/currency/2023/currency-2023.xsd#currency_AllCurrenciesDomain" xlink:label="loc_currencyAllCurrenciesDomain" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srtCurrencyAxis" xlink:to="loc_currencyAllCurrenciesDomain" order="0" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/currency/2023/currency-2023.xsd#currency_AUD" xlink:label="loc_currencyAUD" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_currencyAllCurrenciesDomain" xlink:to="loc_currencyAUD" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_GrantIncome" xlink:label="loc_avxlGrantIncome" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDefinedBenefitPlanDisclosureLineItems" xlink:to="loc_avxlGrantIncome" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned" xlink:label="loc_us-gaapResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDefinedBenefitPlanDisclosureLineItems" xlink:to="loc_us-gaapResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_NonOperatingIncomeFromGrant" xlink:label="loc_avxlNonOperatingIncomeFromGrant" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDefinedBenefitPlanDisclosureLineItems" xlink:to="loc_avxlNonOperatingIncomeFromGrant" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DeferredGrantIncome1" xlink:label="loc_avxlDeferredGrantIncome1" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDefinedBenefitPlanDisclosureLineItems" xlink:to="loc_avxlDeferredGrantIncome1" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherReceivables" xlink:label="loc_us-gaapOtherReceivables" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDefinedBenefitPlanDisclosureLineItems" xlink:to="loc_us-gaapOtherReceivables" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/EquityOfferingsDetailsNarrative" xlink:title="00000023 - Disclosure - Equity Offerings (Details Narrative)">
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DisclosureEquityOfferingsAbstract" xlink:label="loc_avxlDisclosureEquityOfferingsAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_avxlDisclosureEquityOfferingsAbstract" xlink:to="loc_us-gaapStatementTable" order="100" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable" xlink:to="loc_us-gaapStatementLineItems" order="200" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_TypeOfArrangementAxis" xlink:label="loc_us-gaapTypeOfArrangementAxis" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable" xlink:to="loc_us-gaapTypeOfArrangementAxis" order="10" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember" xlink:label="loc_us-gaapArrangementsAndNonarrangementTransactionsMember" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapTypeOfArrangementAxis" xlink:to="loc_us-gaapArrangementsAndNonarrangementTransactionsMember" order="0" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SecuritiesPurchaseAgreementMember" xlink:label="loc_avxlSecuritiesPurchaseAgreementMember" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapArrangementsAndNonarrangementTransactionsMember" xlink:to="loc_avxlSecuritiesPurchaseAgreementMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_EquityOfferingSalesAgreementMember" xlink:label="loc_avxlEquityOfferingSalesAgreementMember" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapArrangementsAndNonarrangementTransactionsMember" xlink:to="loc_avxlEquityOfferingSalesAgreementMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PurchaseAgreement2023Member" xlink:label="loc_avxlPurchaseAgreement2023Member" />
      <link:presentationArc order="80" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapArrangementsAndNonarrangementTransactionsMember" xlink:to="loc_avxlPurchaseAgreement2023Member" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PurchaseAgreement2019Member" xlink:label="loc_avxlPurchaseAgreement2019Member" />
      <link:presentationArc order="170" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapArrangementsAndNonarrangementTransactionsMember" xlink:to="loc_avxlPurchaseAgreement2019Member" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_LegalEntityAxis" xlink:label="loc_deiLegalEntityAxis" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable" xlink:to="loc_deiLegalEntityAxis" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityDomain" xlink:label="loc_deiEntityDomain" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiLegalEntityAxis" xlink:to="loc_deiEntityDomain" order="0" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_LincolnParkCapitalFundLLCMember" xlink:label="loc_avxlLincolnParkCapitalFundLLCMember" />
      <link:presentationArc order="80" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiEntityDomain" xlink:to="loc_avxlLincolnParkCapitalFundLLCMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementClassOfStockAxis" xlink:label="loc_us-gaapStatementClassOfStockAxis" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable" xlink:to="loc_us-gaapStatementClassOfStockAxis" order="30" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ClassOfStockDomain" xlink:label="loc_us-gaapClassOfStockDomain" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementClassOfStockAxis" xlink:to="loc_us-gaapClassOfStockDomain" order="0" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CommonStockIncludingCommitmentSharesMember" xlink:label="loc_avxlCommonStockIncludingCommitmentSharesMember" />
      <link:presentationArc order="90" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapClassOfStockDomain" xlink:to="loc_avxlCommonStockIncludingCommitmentSharesMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CommonStockExcludingCommitmentSharesMember" xlink:label="loc_avxlCommonStockExcludingCommitmentSharesMember" />
      <link:presentationArc order="110" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapClassOfStockDomain" xlink:to="loc_avxlCommonStockExcludingCommitmentSharesMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_CommitmentSharesMember" xlink:label="loc_avxlCommitmentSharesMember" />
      <link:presentationArc order="150" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapClassOfStockDomain" xlink:to="loc_avxlCommitmentSharesMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaapCommonStockMember" />
      <link:presentationArc order="200" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapClassOfStockDomain" xlink:to="loc_us-gaapCommonStockMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction" xlink:label="loc_us-gaapSaleOfStockNumberOfSharesIssuedInTransaction" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapSaleOfStockNumberOfSharesIssuedInTransaction" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SaleOfStockPricePerShare" xlink:label="loc_us-gaapSaleOfStockPricePerShare" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapSaleOfStockPricePerShare" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SaleOfStockConsiderationReceivedOnTransaction" xlink:label="loc_us-gaapSaleOfStockConsiderationReceivedOnTransaction" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapSaleOfStockConsiderationReceivedOnTransaction" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromIssuanceInitialPublicOffering" xlink:label="loc_us-gaapProceedsFromIssuanceInitialPublicOffering" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapProceedsFromIssuanceInitialPublicOffering" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PercentageOfGrossProceedsFromSales" xlink:label="loc_avxlPercentageOfGrossProceedsFromSales" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlPercentageOfGrossProceedsFromSales" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SaleOfStockConsiderationReceivedPerTransaction" xlink:label="loc_us-gaapSaleOfStockConsiderationReceivedPerTransaction" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapSaleOfStockConsiderationReceivedPerTransaction" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SoldForGrossProceedsAmount" xlink:label="loc_avxlSoldForGrossProceedsAmount" />
      <link:presentationArc order="60" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSoldForGrossProceedsAmount" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_SalesOfAgreementAmount" xlink:label="loc_avxlSalesOfAgreementAmount" />
      <link:presentationArc order="70" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlSalesOfAgreementAmount" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ValueOfSharesObligatedToPurchase" xlink:label="loc_avxlValueOfSharesObligatedToPurchase" />
      <link:presentationArc order="80" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlValueOfSharesObligatedToPurchase" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:label="loc_us-gaapStockIssuedDuringPeriodSharesNewIssues" />
      <link:presentationArc order="90" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStockIssuedDuringPeriodSharesNewIssues" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_NumberOfSharesObligatedToPurchaseProrataBasic" xlink:label="loc_avxlNumberOfSharesObligatedToPurchaseProrataBasic" />
      <link:presentationArc order="100" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlNumberOfSharesObligatedToPurchaseProrataBasic" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromIssuanceOrSaleOfEquity" xlink:label="loc_us-gaapProceedsFromIssuanceOrSaleOfEquity" />
      <link:presentationArc order="110" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapProceedsFromIssuanceOrSaleOfEquity" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_FairValueOfInitialCommitment" xlink:label="loc_avxlFairValueOfInitialCommitment" />
      <link:presentationArc order="120" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlFairValueOfInitialCommitment" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_IncurredExpenses" xlink:label="loc_avxlIncurredExpenses" />
      <link:presentationArc order="130" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_avxlIncurredExpenses" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues" xlink:label="loc_us-gaapStockIssuedDuringPeriodValueNewIssues" />
      <link:presentationArc order="140" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStockIssuedDuringPeriodValueNewIssues" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockIssuedDuringPeriodValueOther" xlink:label="loc_us-gaapStockIssuedDuringPeriodValueOther" />
      <link:presentationArc order="150" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems" xlink:to="loc_us-gaapStockIssuedDuringPeriodValueOther" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails" xlink:title="00000024 - Disclosure - Commitments and Contingencies (Details)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseCost" xlink:label="loc_us-gaapOperatingLeaseCost" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapOperatingLeaseCost" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails1" xlink:title="00000025 - Disclosure - Commitments and Contingencies (Details 1)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PensionContributions" xlink:label="loc_us-gaapPensionContributions" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapPensionContributions" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails2" xlink:title="00000026 - Disclosure - Commitments and Contingencies (Details 2)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaapScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" order="100" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" order="200" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaapAwardTypeAxis" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:to="loc_us-gaapAwardTypeAxis" order="10" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAwardTypeAxis" xlink:to="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" order="0" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PurchaseWarrants1Member" xlink:label="loc_avxlPurchaseWarrants1Member" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:to="loc_avxlPurchaseWarrants1Member" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PurchaseWarrants2Member" xlink:label="loc_avxlPurchaseWarrants2Member" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:to="loc_avxlPurchaseWarrants2Member" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_WarrantsAndRightsOutstandingMaturityDate" xlink:label="loc_us-gaapWarrantsAndRightsOutstandingMaturityDate" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapWarrantsAndRightsOutstandingMaturityDate" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails3" xlink:title="00000027 - Disclosure - Commitments and Contingencies (Details 3)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OffsettingAssetsTable" xlink:label="loc_us-gaapOffsettingAssetsTable" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapOffsettingAssetsTable" order="100" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OffsettingAssetsLineItems" xlink:label="loc_us-gaapOffsettingAssetsLineItems" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsTable" xlink:to="loc_us-gaapOffsettingAssetsLineItems" order="200" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_us-gaapDerivativeInstrumentRiskAxis" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsTable" xlink:to="loc_us-gaapDerivativeInstrumentRiskAxis" order="10" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaapDerivativeContractTypeDomain" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDerivativeInstrumentRiskAxis" xlink:to="loc_us-gaapDerivativeContractTypeDomain" order="0" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockOptionMember" xlink:label="loc_us-gaapStockOptionMember" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDerivativeContractTypeDomain" xlink:to="loc_us-gaapStockOptionMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" />
      <link:presentationArc order="60" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod" />
      <link:presentationArc order="70" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice" />
      <link:presentationArc order="80" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice" xlink:label="loc_avxlShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice" />
      <link:presentationArc order="90" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_avxlShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="loc_us-gaapStockIssuedDuringPeriodSharesStockOptionsExercised" />
      <link:presentationArc order="100" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapStockIssuedDuringPeriodSharesStockOptionsExercised" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" />
      <link:presentationArc order="110" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice" xlink:label="loc_avxlShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice" />
      <link:presentationArc order="120" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_avxlShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue" />
      <link:presentationArc order="130" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_2" />
      <link:presentationArc order="140" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_2" />
      <link:presentationArc order="150" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_2" />
      <link:presentationArc order="160" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_2" />
      <link:presentationArc order="170" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber" />
      <link:presentationArc order="180" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice" />
      <link:presentationArc order="190" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue" />
      <link:presentationArc order="200" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1" />
      <link:presentationArc order="210" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails4" xlink:title="00000028 - Disclosure - Commitments and Contingencies (Details 4)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OffsettingAssetsTable" xlink:label="loc_us-gaapOffsettingAssetsTable" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapOffsettingAssetsTable" order="100" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OffsettingAssetsLineItems" xlink:label="loc_us-gaapOffsettingAssetsLineItems" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsTable" xlink:to="loc_us-gaapOffsettingAssetsLineItems" order="200" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_us-gaapDerivativeInstrumentRiskAxis" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsTable" xlink:to="loc_us-gaapDerivativeInstrumentRiskAxis" order="10" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaapDerivativeContractTypeDomain" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDerivativeInstrumentRiskAxis" xlink:to="loc_us-gaapDerivativeContractTypeDomain" order="0" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockOptionMember" xlink:label="loc_us-gaapStockOptionMember" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDerivativeContractTypeDomain" xlink:to="loc_us-gaapStockOptionMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis" xlink:label="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsTable" xlink:to="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:label="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis" xlink:to="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" order="0" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionPrice1Member" xlink:label="loc_avxlOptionPrice1Member" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:to="loc_avxlOptionPrice1Member" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionPrice2Member" xlink:label="loc_avxlOptionPrice2Member" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:to="loc_avxlOptionPrice2Member" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionPrice3Member" xlink:label="loc_avxlOptionPrice3Member" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:to="loc_avxlOptionPrice3Member" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionPrice4Member" xlink:label="loc_avxlOptionPrice4Member" />
      <link:presentationArc order="70" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:to="loc_avxlOptionPrice4Member" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionPrice5Member" xlink:label="loc_avxlOptionPrice5Member" />
      <link:presentationArc order="90" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:to="loc_avxlOptionPrice5Member" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit" xlink:label="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit" xlink:label="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice" />
      <link:presentationArc order="60" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOffsettingAssetsLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails5" xlink:title="00000029 - Disclosure - Commitments and Contingencies (Details 5)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LossContingenciesTable" xlink:label="loc_us-gaapLossContingenciesTable" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapLossContingenciesTable" order="100" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LossContingenciesLineItems" xlink:label="loc_us-gaapLossContingenciesLineItems" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLossContingenciesTable" xlink:to="loc_us-gaapLossContingenciesLineItems" order="200" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaapIncomeStatementLocationAxis" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLossContingenciesTable" xlink:to="loc_us-gaapIncomeStatementLocationAxis" order="10" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaapIncomeStatementLocationDomain" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementLocationAxis" xlink:to="loc_us-gaapIncomeStatementLocationDomain" order="0" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_GeneralAndAdministrativeExpenseMember" xlink:label="loc_us-gaapGeneralAndAdministrativeExpenseMember" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementLocationDomain" xlink:to="loc_us-gaapGeneralAndAdministrativeExpenseMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ResearchAndDevelopmentExpenseMember" xlink:label="loc_us-gaapResearchAndDevelopmentExpenseMember" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementLocationDomain" xlink:to="loc_us-gaapResearchAndDevelopmentExpenseMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaapShareBasedCompensation" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLossContingenciesLineItems" xlink:to="loc_us-gaapShareBasedCompensation" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetails6" xlink:title="00000030 - Disclosure - Commitments and Contingencies (Details 6)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative" xlink:title="00000031 - Disclosure - Commitments and Contingencies (Details Narrative)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaapScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_us-gaapScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" order="100" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" order="200" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PlanNameAxis" xlink:label="loc_us-gaapPlanNameAxis" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:to="loc_us-gaapPlanNameAxis" order="10" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PlanNameDomain" xlink:label="loc_us-gaapPlanNameDomain" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapPlanNameAxis" xlink:to="loc_us-gaapPlanNameDomain" order="0" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_StockOptionPlan2015Member" xlink:label="loc_avxlStockOptionPlan2015Member" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapPlanNameDomain" xlink:to="loc_avxlStockOptionPlan2015Member" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_StockOptionPlan2019Member" xlink:label="loc_avxlStockOptionPlan2019Member" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapPlanNameDomain" xlink:to="loc_avxlStockOptionPlan2019Member" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_StockOptionPlan2022Member" xlink:label="loc_avxlStockOptionPlan2022Member" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapPlanNameDomain" xlink:to="loc_avxlStockOptionPlan2022Member" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1" xlink:label="loc_us-gaapOperatingLeaseWeightedAverageRemainingLeaseTerm1" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapOperatingLeaseWeightedAverageRemainingLeaseTerm1" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ClassOfWarrantOrRightOutstanding" xlink:label="loc_us-gaapClassOfWarrantOrRightOutstanding" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapClassOfWarrantOrRightOutstanding" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_WarrantsOutstandingWeightedAverageExercise" xlink:label="loc_avxlWarrantsOutstandingWeightedAverageExercise" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_avxlWarrantsOutstandingWeightedAverageExercise" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance" xlink:label="loc_us-gaapCommonStockCapitalSharesReservedForFutureIssuance" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapCommonStockCapitalSharesReservedForFutureIssuance" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OptionIssued" xlink:label="loc_avxlOptionIssued" />
      <link:presentationArc order="60" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_avxlOptionIssued" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant" />
      <link:presentationArc order="70" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue" />
      <link:presentationArc order="80" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" />
      <link:presentationArc order="90" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2" xlink:label="loc_us-gaapSharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2" />
      <link:presentationArc order="100" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapSharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AllocatedShareBasedCompensationExpense" xlink:label="loc_us-gaapAllocatedShareBasedCompensationExpense" />
      <link:presentationArc order="110" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapAllocatedShareBasedCompensationExpense" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions" xlink:label="loc_us-gaapEmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions" />
      <link:presentationArc order="120" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:to="loc_us-gaapEmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxesDetails" xlink:title="00000032 - Disclosure - Income Taxes (Details)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaapIncomeTaxDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic" xlink:label="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign" xlink:label="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:label="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxesDetails1" xlink:title="00000033 - Disclosure - Income Taxes (Details 1)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaapIncomeTaxDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwards" xlink:label="loc_us-gaapDeferredTaxAssetsOperatingLossCarryforwards" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapDeferredTaxAssetsOperatingLossCarryforwards" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment" xlink:label="loc_us-gaapDeferredTaxAssetsInProcessResearchAndDevelopment" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapDeferredTaxAssetsInProcessResearchAndDevelopment" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" xlink:label="loc_us-gaapDeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapDeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DeferredTaxAssetsResearchAndDevelopmentCapitalization" xlink:label="loc_avxlDeferredTaxAssetsResearchAndDevelopmentCapitalization" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_avxlDeferredTaxAssetsResearchAndDevelopmentCapitalization" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_DeferredTaxAssetsUnpaidCharges" xlink:label="loc_avxlDeferredTaxAssetsUnpaidCharges" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_avxlDeferredTaxAssetsUnpaidCharges" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets" xlink:label="loc_us-gaapDeferredTaxAssetsGoodwillAndIntangibleAssets" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapDeferredTaxAssetsGoodwillAndIntangibleAssets" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsUnrealizedCurrencyLosses" xlink:label="loc_us-gaapDeferredTaxAssetsUnrealizedCurrencyLosses" />
      <link:presentationArc order="60" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapDeferredTaxAssetsUnrealizedCurrencyLosses" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsValuationAllowance" xlink:label="loc_us-gaapDeferredTaxAssetsValuationAllowance" />
      <link:presentationArc order="70" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapDeferredTaxAssetsValuationAllowance" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsNet" xlink:label="loc_us-gaapDeferredTaxAssetsNet" />
      <link:presentationArc order="80" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapDeferredTaxAssetsNet" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxesDetails2" xlink:title="00000034 - Disclosure - Income Taxes (Details 2)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaapIncomeTaxDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate" xlink:label="loc_us-gaapIncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapIncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential" xlink:label="loc_us-gaapIncomeTaxReconciliationForeignIncomeTaxRateDifferential" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapIncomeTaxReconciliationForeignIncomeTaxRateDifferential" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PermanentDifferencesRelatingToStockBasedCompensation" xlink:label="loc_avxlPermanentDifferencesRelatingToStockBasedCompensation" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_avxlPermanentDifferencesRelatingToStockBasedCompensation" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationGiltiAmount" xlink:label="loc_us-gaapEffectiveIncomeTaxRateReconciliationGiltiAmount" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapEffectiveIncomeTaxRateReconciliationGiltiAmount" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_PermanentDifferencesRelatingToSection162m" xlink:label="loc_avxlPermanentDifferencesRelatingToSection162m" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_avxlPermanentDifferencesRelatingToSection162m" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationOtherAdjustments" xlink:label="loc_us-gaapIncomeTaxReconciliationOtherAdjustments" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapIncomeTaxReconciliationOtherAdjustments" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_AdjustmentToTaxAssetsBasedOnSection382" xlink:label="loc_avxlAdjustmentToTaxAssetsBasedOnSection382" />
      <link:presentationArc order="60" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_avxlAdjustmentToTaxAssetsBasedOnSection382" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet" xlink:label="loc_avxlIncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet" />
      <link:presentationArc order="70" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_avxlIncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes" xlink:label="loc_us-gaapIncomeTaxReconciliationStateAndLocalIncomeTaxes" />
      <link:presentationArc order="80" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapIncomeTaxReconciliationStateAndLocalIncomeTaxes" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationPriorYearIncomeTaxes" xlink:label="loc_us-gaapIncomeTaxReconciliationPriorYearIncomeTaxes" />
      <link:presentationArc order="90" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapIncomeTaxReconciliationPriorYearIncomeTaxes" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate" xlink:label="loc_us-gaapIncomeTaxReconciliationChangeInEnactedTaxRate" />
      <link:presentationArc order="100" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapIncomeTaxReconciliationChangeInEnactedTaxRate" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_TaxesExcludingIncomeAndExciseTaxes" xlink:label="loc_us-gaapTaxesExcludingIncomeAndExciseTaxes" />
      <link:presentationArc order="110" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapTaxesExcludingIncomeAndExciseTaxes" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance" xlink:label="loc_us-gaapIncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance" />
      <link:presentationArc order="120" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapIncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit" xlink:label="loc_us-gaapDeferredIncomeTaxExpenseBenefit" />
      <link:presentationArc order="130" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapDeferredIncomeTaxExpenseBenefit" xlink:type="arc" />
    </link:presentationLink>
    <link:presentationLink xlink:type="extended" xlink:role="http://anavex.com/role/IncomeTaxesDetailsNarrative" xlink:title="00000035 - Disclosure - Income Taxes (Details Narrative)">
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaapIncomeTaxDisclosureAbstract" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLossCarryforwardsTable" xlink:label="loc_us-gaapOperatingLossCarryforwardsTable" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxDisclosureAbstract" xlink:to="loc_us-gaapOperatingLossCarryforwardsTable" order="100" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLossCarryforwardsLineItems" xlink:label="loc_us-gaapOperatingLossCarryforwardsLineItems" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingLossCarryforwardsTable" xlink:to="loc_us-gaapOperatingLossCarryforwardsLineItems" order="200" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxAuthorityAxis" xlink:label="loc_us-gaapIncomeTaxAuthorityAxis" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingLossCarryforwardsTable" xlink:to="loc_us-gaapIncomeTaxAuthorityAxis" order="10" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxAuthorityDomain" xlink:label="loc_us-gaapIncomeTaxAuthorityDomain" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxAuthorityAxis" xlink:to="loc_us-gaapIncomeTaxAuthorityDomain" order="0" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_FederalMember" xlink:label="loc_avxlFederalMember" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxAuthorityDomain" xlink:to="loc_avxlFederalMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StateAndLocalJurisdictionMember" xlink:label="loc_us-gaapStateAndLocalJurisdictionMember" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxAuthorityDomain" xlink:to="loc_us-gaapStateAndLocalJurisdictionMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ForeignCountryMember" xlink:label="loc_us-gaapForeignCountryMember" />
      <link:presentationArc order="80" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeTaxAuthorityDomain" xlink:to="loc_us-gaapForeignCountryMember" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2023/elts/srt-2023.xsd#srt_CurrencyAxis" xlink:label="loc_srtCurrencyAxis" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingLossCarryforwardsTable" xlink:to="loc_srtCurrencyAxis" order="20" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/currency/2023/currency-2023.xsd#currency_AllCurrenciesDomain" xlink:label="loc_currencyAllCurrenciesDomain" />
      <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srtCurrencyAxis" xlink:to="loc_currencyAllCurrenciesDomain" order="0" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/currency/2023/currency-2023.xsd#currency_AUD" xlink:label="loc_currencyAUD" />
      <link:presentationArc order="90" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_currencyAllCurrenciesDomain" xlink:to="loc_currencyAUD" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLossCarryforwards" xlink:label="loc_us-gaapOperatingLossCarryforwards" />
      <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_us-gaapOperatingLossCarryforwards" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OperatingLossCarryforwardsDescription" xlink:label="loc_avxlOperatingLossCarryforwardsDescription" />
      <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_avxlOperatingLossCarryforwardsDescription" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_OperatingLossCarryForwardsExpirationYear" xlink:label="loc_avxlOperatingLossCarryForwardsExpirationYear" />
      <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_avxlOperatingLossCarryForwardsExpirationYear" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment" xlink:label="loc_us-gaapIncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment" />
      <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_us-gaapIncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="avxl-20230930.xsd#avxl_ResearchAndDevelopmentTaxCreditsYear" xlink:label="loc_avxlResearchAndDevelopmentTaxCreditsYear" />
      <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_avxlResearchAndDevelopmentTaxCreditsYear" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsGross" xlink:label="loc_us-gaapDeferredTaxAssetsGross" />
      <link:presentationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_us-gaapDeferredTaxAssetsGross" xlink:type="arc" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch" xlink:label="loc_us-gaapDeferredTaxAssetsTaxCreditCarryforwardsResearch" />
      <link:presentationArc order="60" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_us-gaapDeferredTaxAssetsTaxCreditCarryforwardsResearch" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" />
      <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount" xlink:label="loc_us-gaapValuationAllowanceDeferredTaxAssetChangeInAmount" />
      <link:presentationArc order="70" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingLossCarryforwardsLineItems" xlink:to="loc_us-gaapValuationAllowanceDeferredTaxAssetChangeInAmount" xlink:type="arc" />
    </link:presentationLink>
</link:linkbase>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>17
<FILENAME>R1.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649477438064">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Cover - USD ($)<br> $ in Millions</strong></div></th>
<th class="th" colspan="1">12 Months Ended</th>
<th class="th" colspan="1"></th>
<th class="th" colspan="1"></th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Nov. 24, 2023</div></th>
<th class="th"><div>Mar. 31, 2023</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_CoverAbstract', window );"><strong>Cover [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_DocumentType', window );">Document Type</a></td>
<td class="text">10-K<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_AmendmentFlag', window );">Amendment Flag</a></td>
<td class="text">false<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_DocumentAnnualReport', window );">Document Annual Report</a></td>
<td class="text">true<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_DocumentTransitionReport', window );">Document Transition Report</a></td>
<td class="text">false<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_DocumentPeriodEndDate', window );">Document Period End Date</a></td>
<td class="text">Sep. 30,  2023<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_DocumentFiscalPeriodFocus', window );">Document Fiscal Period Focus</a></td>
<td class="text">FY<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_DocumentFiscalYearFocus', window );">Document Fiscal Year Focus</a></td>
<td class="text">2023<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_CurrentFiscalYearEndDate', window );">Current Fiscal Year End Date</a></td>
<td class="text">--09-30<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityFileNumber', window );">Entity File Number</a></td>
<td class="text">001-37606<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityRegistrantName', window );">Entity Registrant Name</a></td>
<td class="text">ANAVEX LIFE SCIENCES CORP.<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityCentralIndexKey', window );">Entity Central Index Key</a></td>
<td class="text">0001314052<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityTaxIdentificationNumber', window );">Entity Tax Identification Number</a></td>
<td class="text">98-0608404<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityIncorporationStateCountryCode', window );">Entity Incorporation, State or Country Code</a></td>
<td class="text">NV<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressAddressLine1', window );">Entity Address, Address Line One</a></td>
<td class="text">630 5th Avenue<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressAddressLine2', window );">Entity Address, Address Line Two</a></td>
<td class="text">20th Floor<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressCityOrTown', window );">Entity Address, City or Town</a></td>
<td class="text">New York<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressStateOrProvince', window );">Entity Address, State or Province</a></td>
<td class="text">NY<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressCountry', window );">Entity Address, Country</a></td>
<td class="text">US<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressPostalZipCode', window );">Entity Address, Postal Zip Code</a></td>
<td class="text">10111<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_CityAreaCode', window );">City Area Code</a></td>
<td class="text">844<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_LocalPhoneNumber', window );">Local Phone Number</a></td>
<td class="text">689-3939<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_Security12bTitle', window );">Title of 12(b) Security</a></td>
<td class="text">Common
    Stock, $0.001 par value<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_TradingSymbol', window );">Trading Symbol</a></td>
<td class="text">AVXL<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_SecurityExchangeName', window );">Security Exchange Name</a></td>
<td class="text">NASDAQ<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityWellKnownSeasonedIssuer', window );">Entity Well-known Seasoned Issuer</a></td>
<td class="text">Yes<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityVoluntaryFilers', window );">Entity Voluntary Filers</a></td>
<td class="text">No<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityCurrentReportingStatus', window );">Entity Current Reporting Status</a></td>
<td class="text">Yes<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityInteractiveDataCurrent', window );">Entity Interactive Data Current</a></td>
<td class="text">Yes<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityFilerCategory', window );">Entity Filer Category</a></td>
<td class="text">Large Accelerated Filer<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntitySmallBusiness', window );">Entity Small Business</a></td>
<td class="text">false<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityEmergingGrowthCompany', window );">Entity Emerging Growth Company</a></td>
<td class="text">false<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityShellCompany', window );">Entity Shell Company</a></td>
<td class="text">false<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityPublicFloat', window );">Entity Public Float</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 667<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityCommonStockSharesOutstanding', window );">Entity Common Stock, Shares Outstanding</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">82,086,511<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_IcfrAuditorAttestationFlag', window );">ICFR Auditor Attestation Flag</a></td>
<td class="text">true<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_DocumentFinStmtErrorCorrectionFlag', window );">Document Financial Statement Error Correction [Flag]</a></td>
<td class="text">false<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_AuditorName', window );">Auditor Name</a></td>
<td class="text">GRANT THORNTON LLP<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_AuditorLocation', window );">Auditor Location</a></td>
<td class="text">Melville, New York<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_AuditorFirmId', window );">Auditor Firm ID</a></td>
<td class="text">248<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_AmendmentFlag">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the XBRL content amends previously-filed or accepted submission.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_AmendmentFlag</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_AuditorFirmId">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>PCAOB issued Audit Firm Identifier</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 10-K<br> -Number 249<br> -Section 310<br><br>Reference 2: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 20-F<br> -Number 249<br> -Section 220<br> -Subsection f<br><br>Reference 3: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 40-F<br> -Number 249<br> -Section 240<br> -Subsection f<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_AuditorFirmId</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:nonemptySequenceNumberItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_AuditorLocation">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 10-K<br> -Number 249<br> -Section 310<br><br>Reference 2: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 20-F<br> -Number 249<br> -Section 220<br> -Subsection f<br><br>Reference 3: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 40-F<br> -Number 249<br> -Section 240<br> -Subsection f<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_AuditorLocation</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:internationalNameItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_AuditorName">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 10-K<br> -Number 249<br> -Section 310<br><br>Reference 2: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 20-F<br> -Number 249<br> -Section 220<br> -Subsection f<br><br>Reference 3: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 40-F<br> -Number 249<br> -Section 240<br> -Subsection f<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_AuditorName</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:internationalNameItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_CityAreaCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Area code of city</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_CityAreaCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_CoverAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Cover page.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_CoverAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_CurrentFiscalYearEndDate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>End date of current fiscal year in the format --MM-DD.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_CurrentFiscalYearEndDate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:gMonthDayItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentAnnualReport">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true only for a form used as an annual report.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 10-K<br> -Number 249<br> -Section 310<br><br>Reference 2: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 20-F<br> -Number 249<br> -Section 220<br> -Subsection f<br><br>Reference 3: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 40-F<br> -Number 249<br> -Section 240<br> -Subsection f<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentAnnualReport</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentFinStmtErrorCorrectionFlag">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Indicates whether any of the financial statement period in the filing include a restatement due to error correction.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation S-K<br> -Number 229<br> -Section 402<br> -Subsection w<br><br>Reference 2: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 10-K<br> -Number 249<br> -Section 310<br><br>Reference 3: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 20-F<br> -Number 249<br> -Section 220<br> -Subsection f<br><br>Reference 4: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 40-F<br> -Number 249<br> -Section 240<br> -Subsection f<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentFinStmtErrorCorrectionFlag</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentFiscalPeriodFocus">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Fiscal period values are FY, Q1, Q2, and Q3.  1st, 2nd and 3rd quarter 10-Q or 10-QT statements have value Q1, Q2, and Q3 respectively, with 10-K, 10-KT or other fiscal year statements having FY.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentFiscalPeriodFocus</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:fiscalPeriodItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentFiscalYearFocus">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>This is focus fiscal year of the document report in YYYY format. For a 2006 annual report, which may also provide financial information from prior periods, fiscal 2006 should be given as the fiscal year focus. Example: 2006.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentFiscalYearFocus</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:gYearItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentPeriodEndDate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>For the EDGAR submission types of Form 8-K: the date of the report, the date of the earliest event reported; for the EDGAR submission types of Form N-1A: the filing date; for all other submission types: the end of the reporting or transition period.  The format of the date is YYYY-MM-DD.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentPeriodEndDate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:dateItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentTransitionReport">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true only for a form used as a transition report.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Forms 10-K, 10-Q, 20-F<br> -Number 240<br> -Section 13<br> -Subsection a-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentTransitionReport</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentType">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The type of document being provided (such as 10-K, 10-Q, 485BPOS, etc). The document type is limited to the same value as the supporting SEC submission type, or the word 'Other'.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentType</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:submissionTypeItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressAddressLine1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Address Line 1 such as Attn, Building Name, Street Name</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressAddressLine1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressAddressLine2">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Address Line 2 such as Street or Suite number</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressAddressLine2</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressCityOrTown">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Name of the City or Town</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressCityOrTown</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressCountry">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>ISO 3166-1 alpha-2 country code.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressCountry</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:countryCodeItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressPostalZipCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Code for the postal or zip code</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressPostalZipCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressStateOrProvince">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Name of the state or province.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressStateOrProvince</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:stateOrProvinceItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityCentralIndexKey">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>A unique 10-digit SEC-issued value to identify entities that have filed disclosures with the SEC. It is commonly abbreviated as CIK.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityCentralIndexKey</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:centralIndexKeyItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityCommonStockSharesOutstanding">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Indicate number of shares or other units outstanding of each of registrant's classes of capital or common stock or other ownership interests, if and as stated on cover of related periodic report. Where multiple classes or units exist define each class/interest by adding class of stock items such as Common Class A [Member], Common Class B [Member] or Partnership Interest [Member] onto the Instrument [Domain] of the Entity Listings, Instrument.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityCommonStockSharesOutstanding</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityCurrentReportingStatus">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Indicate 'Yes' or 'No' whether registrants (1) have filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that registrants were required to file such reports), and (2) have been subject to such filing requirements for the past 90 days. This information should be based on the registrant's current or most recent filing containing the related disclosure.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityCurrentReportingStatus</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:yesNoItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityEmergingGrowthCompany">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Indicate if registrant meets the emerging growth company criteria.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityEmergingGrowthCompany</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityFileNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Commission file number. The field allows up to 17 characters. The prefix may contain 1-3 digits, the sequence number may contain 1-8 digits, the optional suffix may contain 1-4 characters, and the fields are separated with a hyphen.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityFileNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:fileNumberItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityFilerCategory">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Indicate whether the registrant is one of the following: Large Accelerated Filer, Accelerated Filer, Non-accelerated Filer. Definitions of these categories are stated in Rule 12b-2 of the Exchange Act. This information should be based on the registrant's current or most recent filing containing the related disclosure.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityFilerCategory</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:filerCategoryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityIncorporationStateCountryCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Two-character EDGAR code representing the state or country of incorporation.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityIncorporationStateCountryCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:edgarStateCountryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityInteractiveDataCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit such files).</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation S-T<br> -Number 232<br> -Section 405<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityInteractiveDataCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:yesNoItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityPublicFloat">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The aggregate market value of the voting and non-voting common equity held by non-affiliates computed by reference to the price at which the common equity was last sold, or the average bid and asked price of such common equity, as of the last business day of the registrant's most recently completed second fiscal quarter.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityPublicFloat</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityRegistrantName">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The exact name of the entity filing the report as specified in its charter, which is required by forms filed with the SEC.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityRegistrantName</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityShellCompany">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the registrant is a shell company as defined in Rule 12b-2 of the Exchange Act.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityShellCompany</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntitySmallBusiness">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Indicates that the company is a Smaller Reporting Company (SRC).</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntitySmallBusiness</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityTaxIdentificationNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The Tax Identification Number (TIN), also known as an Employer Identification Number (EIN), is a unique 9-digit value assigned by the IRS.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityTaxIdentificationNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:employerIdItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityVoluntaryFilers">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Indicate 'Yes' or 'No' if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityVoluntaryFilers</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:yesNoItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityWellKnownSeasonedIssuer">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Indicate 'Yes' or 'No' if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Is used on Form Type: 10-K, 10-Q, 8-K, 20-F, 6-K, 10-K/A, 10-Q/A, 20-F/A, 6-K/A, N-CSR, N-Q, N-1A.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Securities Act<br> -Number 230<br> -Section 405<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityWellKnownSeasonedIssuer</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:yesNoItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_IcfrAuditorAttestationFlag">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 10-K<br> -Number 249<br> -Section 310<br><br>Reference 2: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 20-F<br> -Number 249<br> -Section 220<br> -Subsection f<br><br>Reference 3: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 40-F<br> -Number 249<br> -Section 240<br> -Subsection f<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_IcfrAuditorAttestationFlag</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_LocalPhoneNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Local phone number for entity.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_LocalPhoneNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_Security12bTitle">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Title of a 12(b) registered security.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_Security12bTitle</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:securityTitleItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_SecurityExchangeName">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Name of the Exchange on which a security is registered.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection d1-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_SecurityExchangeName</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:edgarExchangeCodeItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_TradingSymbol">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Trading symbol of an instrument as listed on an exchange.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_TradingSymbol</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:tradingSymbolItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>18
<FILENAME>R2.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649474912384">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Consolidated Balance Sheets - USD ($)<br> $ in Thousands</strong></div></th>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AssetsCurrentAbstract', window );"><strong>Current</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CashAndCashEquivalentsAtCarryingValue', window );">Cash and cash equivalents</a></td>
<td class="nump">$ 151,024<span></span>
</td>
<td class="nump">$ 149,158<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxesReceivable', window );">Incentive and tax receivables</a></td>
<td class="nump">2,709<span></span>
</td>
<td class="nump">3,193<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_PrepaidExpenseAndOtherAssetsCurrent', window );">Prepaid expenses and other current assets</a></td>
<td class="nump">653<span></span>
</td>
<td class="nump">354<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_Assets', window );">Total Assets</a></td>
<td class="nump">154,386<span></span>
</td>
<td class="nump">152,705<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_LiabilitiesCurrentAbstract', window );"><strong>Current Liabilities</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AccountsPayableCurrent', window );">Accounts payable</a></td>
<td class="nump">4,322<span></span>
</td>
<td class="nump">3,825<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AccruedLiabilitiesCurrent', window );">Accrued liabilities - Note 3</a></td>
<td class="nump">7,295<span></span>
</td>
<td class="nump">5,945<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DeferredRentCredit', window );">Deferred grant income - Note 4</a></td>
<td class="nump">917<span></span>
</td>
<td class="nump">444<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_Liabilities', window );">Total Liabilities</a></td>
<td class="nump">12,534<span></span>
</td>
<td class="nump">10,214<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CommitmentsAndContingencies', window );">Commitments and Contingencies - Note 6</a></td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_PreferredStockValue', window );">Capital stock Authorized:10,000,000 preferred stock, par value $0.001 per share</a></td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CommonStockValue', window );">Capital stock Authorized: 200,000,000 common stock, par value $0.001 per Issued and outstanding: 82,066,511 common shares (2022 - 77,942,815)</a></td>
<td class="nump">82<span></span>
</td>
<td class="nump">78<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AdditionalPaidInCapitalCommonStock', window );">Additional paid-in capital</a></td>
<td class="nump">434,839<span></span>
</td>
<td class="nump">387,977<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_RetainedEarningsAccumulatedDeficit', window );">Accumulated deficit</a></td>
<td class="num">(293,069)<span></span>
</td>
<td class="num">(245,564)<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Total Stockholders' Equity</a></td>
<td class="nump">141,852<span></span>
</td>
<td class="nump">142,491<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_LiabilitiesAndStockholdersEquity', window );">Total Liabilities and Stockholders' Equity</a></td>
<td class="nump">$ 154,386<span></span>
</td>
<td class="nump">$ 152,705<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AccountsPayableCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Carrying value as of the balance sheet date of liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received that are used in an entity's business. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 852<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 10<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481372/852-10-55-10<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.19(a))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AccountsPayableCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AccruedLiabilitiesCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.20)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AccruedLiabilitiesCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AdditionalPaidInCapitalCommonStock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Value received from shareholders in common stock-related transactions that are in excess of par value or stated value and amounts received from other stock-related transactions. Includes only common stock transactions (excludes preferred stock transactions). May be called contributed capital, capital in excess of par, capital surplus, or paid-in capital.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(30)(a)(1))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AdditionalPaidInCapitalCommonStock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_Assets">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Sum of the carrying amounts as of the balance sheet date of all assets that are recognized. Assets are probable future economic benefits obtained or controlled by an entity as a result of past transactions or events.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 810<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (bb)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481203/810-10-50-3<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 810<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 25<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481231/810-10-45-25<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480678/235-10-S99-1<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 323<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481687/323-10-50-3<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 825<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482907/825-10-50-28<br><br>Reference 6: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 852<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 10<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481372/852-10-55-10<br><br>Reference 7: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 946<br> -SubTopic 830<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 12<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480167/946-830-55-12<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 944<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03(a)(12))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479440/944-210-S99-1<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 22<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-22<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.6-04(8))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479617/946-210-S99-1<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(18))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(i))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 13: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(ii))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 14: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii)(A))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iv))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 17: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(5))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(i))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 19: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(A))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 20: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(B))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 21: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iv))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 22: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(5))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 23: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 852<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 7<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481404/852-10-50-7<br><br>Reference 24: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-30<br><br>Reference 25: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (d)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32<br><br>Reference 26: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 942<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03(11))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479853/942-210-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_Assets</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AssetsCurrentAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AssetsCurrentAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CashAndCashEquivalentsAtCarryingValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(1))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 1<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483467/210-10-45-1<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 4<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-4<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CashAndCashEquivalentsAtCarryingValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommitmentsAndContingencies">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Represents the caption on the face of the balance sheet to indicate that the entity has entered into (1) purchase or supply arrangements that will require expending a portion of its resources to meet the terms thereof, and (2) is exposed to potential losses or, less frequently, gains, arising from (a) possible claims against a company's resources due to future performance under contract terms, and (b) possible losses or likely gains from uncertainties that will ultimately be resolved when one or more future events that are deemed likely to occur do occur or fail to occur.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 944<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03(a)(19))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479440/944-210-S99-1<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.6-04(15))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479617/946-210-S99-1<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03.17)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479853/942-210-S99-1<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.25)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommitmentsAndContingencies</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommonStockValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Aggregate par or stated value of issued nonredeemable common stock (or common stock redeemable solely at the option of the issuer). This item includes treasury stock repurchased by the entity. Note: elements for number of nonredeemable common shares, par value and other disclosure concepts are in another section within stockholders' equity.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 852<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 10<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481372/852-10-55-10<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 944<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03(a)(22))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479440/944-210-S99-1<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommonStockValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DeferredRentCredit">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of excess of rental payment required by lease over rental income recognized.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/otherTransitionRef<br> -Topic 840<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 25<br> -Paragraph 1<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481178/840-20-25-1<br><br>Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 842<br> -SubTopic 30<br> -Name Accounting Standards Codification<br> -Section 25<br> -Paragraph 11<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479341/842-30-25-11<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DeferredRentCredit</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxesReceivable">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Carrying amount due within one year of the balance sheet date (or one operating cycle, if longer) from tax authorities as of the balance sheet date representing refunds of overpayments or recoveries based on agreed-upon resolutions of disputes.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(3)(a)(4))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03.10)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479853/942-210-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxesReceivable</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_Liabilities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Sum of the carrying amounts as of the balance sheet date of all liabilities that are recognized. Liabilities are probable future sacrifices of economic benefits arising from present obligations of an entity to transfer assets or provide services to other entities in the future.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 810<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481203/810-10-50-3<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 810<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 25<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481231/810-10-45-25<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 810<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (bb)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481203/810-10-50-3<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480678/235-10-S99-1<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 323<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481687/323-10-50-3<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 825<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482907/825-10-50-28<br><br>Reference 7: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 946<br> -SubTopic 830<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 12<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480167/946-830-55-12<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.6-04(14))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479617/946-210-S99-1<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(i))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 10: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(ii))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii)(A))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iv))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(5))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(i))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(A))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(B))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 17: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iv))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(5))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 19: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 852<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 7<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481404/852-10-50-7<br><br>Reference 20: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 852<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 7<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481404/852-10-50-7<br><br>Reference 21: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (d)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-30<br><br>Reference 22: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.19-26)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_Liabilities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LiabilitiesAndStockholdersEquity">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of liabilities and equity items, including the portion of equity attributable to noncontrolling interests, if any.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 852<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 10<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481372/852-10-55-10<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 944<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03(a)(25))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479440/944-210-S99-1<br><br>Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480678/235-10-S99-1<br><br>Reference 4: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 323<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481687/323-10-50-3<br><br>Reference 5: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 825<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482907/825-10-50-28<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 942<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03(23))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479853/942-210-S99-1<br><br>Reference 7: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(32))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LiabilitiesAndStockholdersEquity</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LiabilitiesCurrentAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LiabilitiesCurrentAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PreferredStockValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Aggregate par or stated value of issued nonredeemable preferred stock (or preferred stock redeemable solely at the option of the issuer). This item includes treasury stock repurchased by the entity. Note: elements for number of nonredeemable preferred shares, par value and other disclosure concepts are in another section within stockholders' equity.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 852<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 10<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481372/852-10-55-10<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 944<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03(a)(21))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479440/944-210-S99-1<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(28))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PreferredStockValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PrepaidExpenseAndOtherAssetsCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of asset related to consideration paid in advance for costs that provide economic benefits in future periods, and amount of other assets that are expected to be realized or consumed within one year or the normal operating cycle, if longer.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(9))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PrepaidExpenseAndOtherAssetsCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_RetainedEarningsAccumulatedDeficit">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of accumulated undistributed earnings (deficit).</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 852<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 10<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481372/852-10-55-10<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 944<br> -SubTopic 40<br> -Name Accounting Standards Codification<br> -Section 65<br> -Paragraph 2<br> -Subparagraph (g)(2)(i)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480016/944-40-65-2<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 944<br> -SubTopic 40<br> -Name Accounting Standards Codification<br> -Section 65<br> -Paragraph 2<br> -Subparagraph (h)(2)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480016/944-40-65-2<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 11<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480990/946-20-50-11<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 944<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03(a)(23)(a)(4))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479440/944-210-S99-1<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.6-04(17))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479617/946-210-S99-1<br><br>Reference 7: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 505<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480008/505-10-S99-1<br><br>Reference 8: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(30)(a)(3))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_RetainedEarningsAccumulatedDeficit</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockholdersEquity">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of equity (deficit) attributable to parent. Excludes temporary equity and equity attributable to noncontrolling interest.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 852<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 10<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481372/852-10-55-10<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 946<br> -SubTopic 830<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 12<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480167/946-830-55-12<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.6-04(19))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479617/946-210-S99-1<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.6-05(4))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479617/946-210-S99-2<br><br>Reference 5: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-09(4)(b))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-3<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-09(6))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-3<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-09(7))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-3<br><br>Reference 8: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480678/235-10-S99-1<br><br>Reference 9: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 323<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481687/323-10-50-3<br><br>Reference 10: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 825<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482907/825-10-50-28<br><br>Reference 11: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br><br>Reference 12: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(31))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br><br>Reference 13: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(30))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br><br>Reference 14: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 310<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SAB Topic 4.E)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480418/310-10-S99-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockholdersEquity</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>19
<FILENAME>R3.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649477540416">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Consolidated Balance Sheets (Parenthetical) - $ / shares<br></strong></div></th>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StatementOfFinancialPositionAbstract', window );"><strong>Statement of Financial Position [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_PreferredStockSharesAuthorized', window );">Preferred stock, authorized</a></td>
<td class="nump">10,000,000<span></span>
</td>
<td class="nump">10,000,000<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_PreferredStockParOrStatedValuePerShare', window );">Preferred stock, par value</a></td>
<td class="nump">$ 0.001<span></span>
</td>
<td class="nump">$ 0.001<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CommonStockSharesAuthorized', window );">Common shares, authorized</a></td>
<td class="nump">200,000,000<span></span>
</td>
<td class="nump">200,000,000<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CommonStockParOrStatedValuePerShare', window );">Common shares, par value</a></td>
<td class="nump">$ 0.001<span></span>
</td>
<td class="nump">$ 0.001<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CommonStockSharesIssued', window );">Common shares, issued</a></td>
<td class="nump">82,066,511<span></span>
</td>
<td class="nump">77,942,815<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Common shares, outstanding</a></td>
<td class="nump">82,066,511<span></span>
</td>
<td class="nump">77,942,815<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommonStockParOrStatedValuePerShare">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Face amount or stated value per share of common stock.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommonStockParOrStatedValuePerShare</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommonStockSharesAuthorized">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The maximum number of common shares permitted to be issued by an entity's charter and bylaws.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.6-04(16)(a))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479617/946-210-S99-1<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommonStockSharesAuthorized</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommonStockSharesIssued">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Total number of common shares of an entity that have been sold or granted to shareholders (includes common shares that were issued, repurchased and remain in the treasury). These shares represent capital invested by the firm's shareholders and owners, and may be all or only a portion of the number of shares authorized. Shares issued include shares outstanding and shares held in the treasury.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommonStockSharesIssued</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommonStockSharesOutstanding">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Number of shares of common stock outstanding. Common stock represent the ownership interest in a corporation.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -SubTopic 10<br> -Topic 505<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481112/505-10-50-2<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.6-05(4))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479617/946-210-S99-2<br><br>Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-09(4)(b))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-3<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.6-04(16)(a))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479617/946-210-S99-1<br><br>Reference 5: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-09(7))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-3<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommonStockSharesOutstanding</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PreferredStockParOrStatedValuePerShare">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Face amount or stated value per share of preferred stock nonredeemable or redeemable solely at the option of the issuer.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 505<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 13<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481112/505-10-50-13<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(28))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PreferredStockParOrStatedValuePerShare</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PreferredStockSharesAuthorized">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The maximum number of nonredeemable preferred shares (or preferred stock redeemable solely at the option of the issuer) permitted to be issued by an entity's charter and bylaws.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.6-04(16)(a))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479617/946-210-S99-1<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(28))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PreferredStockSharesAuthorized</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementOfFinancialPositionAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementOfFinancialPositionAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>20
<FILENAME>R4.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649477334192">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Consolidated Statements of Operations and Comprehensive Loss - USD ($)<br> $ in Thousands</strong></div></th>
<th class="th" colspan="3">12 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OperatingExpensesAbstract', window );"><strong>Operating expenses</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_GeneralAndAdministrativeExpense', window );">General and administrative</a></td>
<td class="nump">$ 12,039<span></span>
</td>
<td class="nump">$ 13,070<span></span>
</td>
<td class="nump">$ 9,018<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ResearchAndDevelopmentExpense', window );">Research and development</a></td>
<td class="nump">43,717<span></span>
</td>
<td class="nump">37,916<span></span>
</td>
<td class="nump">32,984<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OperatingExpenses', window );">Total operating expenses</a></td>
<td class="nump">55,756<span></span>
</td>
<td class="nump">50,986<span></span>
</td>
<td class="nump">42,002<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OperatingIncomeLoss', window );">Operating loss</a></td>
<td class="num">(55,756)<span></span>
</td>
<td class="num">(50,986)<span></span>
</td>
<td class="num">(42,002)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_NonoperatingIncomeExpenseAbstract', window );"><strong>Other income (expenses)</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_NonOperatingIncomeFromGrants', window );">Grant income</a></td>
<td class="nump">25<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">54<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_ResearchAndDevelopmentIncentiveIncome', window );">Research and development incentive income</a></td>
<td class="nump">2,718<span></span>
</td>
<td class="nump">3,323<span></span>
</td>
<td class="nump">4,547<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_InterestIncomeExpenseNet', window );">Interest income, net</a></td>
<td class="nump">6,519<span></span>
</td>
<td class="nump">947<span></span>
</td>
<td class="nump">26<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_OtherFinancingExpense', window );">Other financing expense</a></td>
<td class="num">(964)<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax', window );">Foreign exchange loss</a></td>
<td class="num">(40)<span></span>
</td>
<td class="num">(904)<span></span>
</td>
<td class="num">(266)<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_NonoperatingIncomeExpense', window );">Total other income, net</a></td>
<td class="nump">8,258<span></span>
</td>
<td class="nump">3,366<span></span>
</td>
<td class="nump">4,361<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest', window );">Net loss before provision for income taxes</a></td>
<td class="num">(47,498)<span></span>
</td>
<td class="num">(47,620)<span></span>
</td>
<td class="num">(37,641)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CurrentIncomeTaxExpenseBenefit', window );">Income tax expense, current</a></td>
<td class="num">(7)<span></span>
</td>
<td class="num">(358)<span></span>
</td>
<td class="num">(268)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net loss and comprehensive loss</a></td>
<td class="num">$ (47,505)<span></span>
</td>
<td class="num">$ (47,978)<span></span>
</td>
<td class="num">$ (37,909)<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_NonOperatingIncomeFromGrants">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_NonOperatingIncomeFromGrants</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_OtherFinancingExpense">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_OtherFinancingExpense</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_ResearchAndDevelopmentIncentiveIncome">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_ResearchAndDevelopmentIncentiveIncome</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CurrentIncomeTaxExpenseBenefit">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of current income tax expense (benefit) pertaining to taxable income (loss) from continuing operations.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(h)(1)(Note 1))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480678/235-10-S99-1<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB Topic 6.I.Fact.2)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479360/740-10-S99-1<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB Topic 6.I.7)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479360/740-10-S99-1<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 9<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-9<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CurrentIncomeTaxExpenseBenefit</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount, before tax, of realized and unrealized gain (loss) from foreign currency transaction.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.6-07(7))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-1<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 830<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 35<br> -Paragraph 1<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482014/830-20-35-1<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 830<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 1<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481956/830-20-45-1<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 830<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481926/830-20-50-1<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 830<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 17<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481839/830-10-45-17<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ForeignCurrencyTransactionGainLossBeforeTax</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_GeneralAndAdministrativeExpense">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.6-07(2)(a))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-1<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03.4)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483621/220-10-S99-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_GeneralAndAdministrativeExpense</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of income (loss) from continuing operations, including income (loss) from equity method investments, before deduction of income tax expense (benefit), and income (loss) attributable to noncontrolling interest.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 944<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(11))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483586/944-220-S99-1<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 22<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-22<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-30<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32<br><br>Reference 5: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 31<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-31<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 942<br> -SubTopic 235<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-05(b)(2))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479557/942-235-S99-1<br><br>Reference 8: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 25<br> -Paragraph 1<br> -SubTopic 20<br> -Topic 940<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481913/940-20-25-1<br><br>Reference 9: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(10))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483621/220-10-S99-2<br><br>Reference 10: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 942<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(15))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483589/942-220-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InterestIncomeExpenseNet">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The net amount of operating interest income (expense).</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 942<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04.10)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483589/942-220-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InterestIncomeExpenseNet</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetIncomeLoss">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480678/235-10-S99-1<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 323<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481687/323-10-50-3<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 825<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482907/825-10-50-28<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 6<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482765/220-10-50-6<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-3<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (b)(2)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-1<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 815<br> -SubTopic 40<br> -Name Accounting Standards Codification<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480175/815-40-65-1<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 8<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-8<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 9<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-9<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-11<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-11<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 4<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-4<br><br>Reference 13: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 946<br> -SubTopic 830<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 10<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480167/946-830-55-10<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 7<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483581/946-220-45-7<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 944<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(18))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483586/944-220-S99-1<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 22<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-22<br><br>Reference 17: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.6-07(9))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-1<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-09(1)(d))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-3<br><br>Reference 19: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(i))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 20: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(ii))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 21: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii)(A))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 22: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iv))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 23: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(5))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 24: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(i))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 25: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(A))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 26: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(B))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 27: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iv))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 28: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(5))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 29: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-30<br><br>Reference 30: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32<br><br>Reference 31: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 60B<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482689/260-10-45-60B<br><br>Reference 32: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 31<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-31<br><br>Reference 33: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32<br><br>Reference 34: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 205<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 7<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483499/205-20-50-7<br><br>Reference 35: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 230<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 28<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-28<br><br>Reference 36: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 1A<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482790/220-10-45-1A<br><br>Reference 37: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 1B<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482790/220-10-45-1B<br><br>Reference 38: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(20))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483621/220-10-S99-2<br><br>Reference 39: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 942<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(22))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483589/942-220-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetIncomeLoss</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NonoperatingIncomeExpense">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The aggregate amount of income or expense from ancillary business-related activities (that is to say, excluding major activities considered part of the normal operations of the business).</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03.7)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483621/220-10-S99-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NonoperatingIncomeExpense</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NonoperatingIncomeExpenseAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NonoperatingIncomeExpenseAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OperatingExpenses">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Generally recurring costs associated with normal operations except for the portion of these expenses which can be clearly related to production and included in cost of sales or services. Includes selling, general and administrative expense.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OperatingExpenses</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OperatingExpensesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OperatingExpensesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OperatingIncomeLoss">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The net result for the period of deducting operating expenses from operating revenues.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 22<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-22<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-30<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32<br><br>Reference 4: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 31<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-31<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OperatingIncomeLoss</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ResearchAndDevelopmentExpense">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 730<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482916/730-10-50-1<br><br>Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 912<br> -SubTopic 730<br> -Name Accounting Standards Codification<br> -Section 25<br> -Paragraph 1<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482517/912-730-25-1<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 985<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481283/985-20-50-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ResearchAndDevelopmentExpense</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>21
<FILENAME>R5.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649477566944">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Consolidated Statements of Operations and Comprehensive Loss (Parenthetical) - $ / shares<br></strong></div></th>
<th class="th" colspan="3">12 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeStatementAbstract', window );"><strong>Income Statement [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_EarningsPerShareBasic', window );">Net Loss per share, Basic</a></td>
<td class="num">$ (0.60)<span></span>
</td>
<td class="num">$ (0.62)<span></span>
</td>
<td class="num">$ (0.54)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_EarningsPerShareDiluted', window );">Net Loss per share, Diluted</a></td>
<td class="num">$ (0.60)<span></span>
</td>
<td class="num">$ (0.62)<span></span>
</td>
<td class="num">$ (0.54)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic', window );">Weighted average number of shares outstanding, Basic</a></td>
<td class="nump">79,787,596<span></span>
</td>
<td class="nump">76,909,993<span></span>
</td>
<td class="nump">69,802,960<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding', window );">Weighted average number of shares outstanding, Diluted</a></td>
<td class="nump">79,787,596<span></span>
</td>
<td class="nump">76,909,993<span></span>
</td>
<td class="nump">69,802,960<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EarningsPerShareBasic">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The amount of net income (loss) for the period per each share of common stock or unit outstanding during the reporting period.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-3<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 15<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482635/260-10-55-15<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 815<br> -SubTopic 40<br> -Name Accounting Standards Codification<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (e)(4)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480175/815-40-65-1<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 815<br> -SubTopic 40<br> -Name Accounting Standards Codification<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480175/815-40-65-1<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-11<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-11<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 7<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-7<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 2<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482689/260-10-45-2<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 60B<br> -Subparagraph (d)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482689/260-10-45-60B<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 4<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-4<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482662/260-10-50-1<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 10<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482689/260-10-45-10<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(25))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483621/220-10-S99-2<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 942<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(27))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483589/942-220-S99-1<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 944<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(23))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483586/944-220-S99-1<br><br>Reference 16: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 52<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482635/260-10-55-52<br><br>Reference 17: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 7<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482689/260-10-45-7<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EarningsPerShareBasic</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EarningsPerShareDiluted">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The amount of net income (loss) for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-3<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 15<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482635/260-10-55-15<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 815<br> -SubTopic 40<br> -Name Accounting Standards Codification<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (e)(4)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480175/815-40-65-1<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 815<br> -SubTopic 40<br> -Name Accounting Standards Codification<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480175/815-40-65-1<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-11<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-11<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 7<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-7<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 2<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482689/260-10-45-2<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 60B<br> -Subparagraph (d)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482689/260-10-45-60B<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 4<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-4<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482662/260-10-50-1<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(25))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483621/220-10-S99-2<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 942<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(27))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483589/942-220-S99-1<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 944<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(23))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483586/944-220-S99-1<br><br>Reference 15: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 52<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482635/260-10-55-52<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 7<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482689/260-10-45-7<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EarningsPerShareDiluted</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeStatementAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeStatementAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The average number of shares or units issued and outstanding that are used in calculating diluted EPS or earnings per unit (EPU), determined based on the timing of issuance of shares or units in the period.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482662/260-10-50-1<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 16<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482689/260-10-45-16<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Number of [basic] shares or units, after adjustment for contingently issuable shares or units and other shares or units not deemed outstanding, determined by relating the portion of time within a reporting period that common shares or units have been outstanding to the total time in that period.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482662/260-10-50-1<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 10<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482689/260-10-45-10<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_WeightedAverageNumberOfSharesOutstandingBasic</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>22
<FILENAME>R6.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649477337408">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Consolidated Statements of Cash Flows - USD ($)<br> $ in Thousands</strong></div></th>
<th class="th" colspan="3">12 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract', window );"><strong>Cash Flows used in Operating Activities</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net loss</a></td>
<td class="num">$ (47,505)<span></span>
</td>
<td class="num">$ (47,978)<span></span>
</td>
<td class="num">$ (37,909)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract', window );"><strong>Adjustments to reconcile net loss to net cash used in operations:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_NoncashFinancingRelatedCharges', window );">Non-cash financing related charges</a></td>
<td class="nump">845<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensation', window );">Stock-based compensation</a></td>
<td class="nump">16,370<span></span>
</td>
<td class="nump">18,379<span></span>
</td>
<td class="nump">8,231<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract', window );"><strong>Changes in working capital balances related to operations:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInIncomeTaxesReceivable', window );">Incentive and tax receivables</a></td>
<td class="nump">484<span></span>
</td>
<td class="nump">5,944<span></span>
</td>
<td class="num">(4,287)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInPrepaidExpense', window );">Prepaid expenses and deposits</a></td>
<td class="num">(299)<span></span>
</td>
<td class="nump">1<span></span>
</td>
<td class="nump">88<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInAccountsPayable', window );">Accounts payable</a></td>
<td class="nump">497<span></span>
</td>
<td class="num">(914)<span></span>
</td>
<td class="nump">751<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInAccruedLiabilities', window );">Accrued liabilities</a></td>
<td class="nump">1,350<span></span>
</td>
<td class="nump">330<span></span>
</td>
<td class="nump">2,298<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_DeferredGrantIncome', window );">Deferred grant income</a></td>
<td class="nump">473<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">444<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_NetCashProvidedByUsedInOperatingActivities', window );">Net cash used in operating activities</a></td>
<td class="num">(27,785)<span></span>
</td>
<td class="num">(24,238)<span></span>
</td>
<td class="num">(30,384)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract', window );"><strong>Cash Flows provided by Financing Activities</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ProceedsFromIssuanceOfCommonStock', window );">Issuance of common shares</a></td>
<td class="nump">27,875<span></span>
</td>
<td class="nump">20,985<span></span>
</td>
<td class="nump">153,219<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_PaymentsOfStockIssuanceCosts', window );">Share issue costs</a></td>
<td class="text"> <span></span>
</td>
<td class="num">(707)<span></span>
</td>
<td class="num">(5,551)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ProceedsFromWarrantExercises', window );">Proceeds from exercise of warrants</a></td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">1,467<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ProceedsFromStockOptionsExercised', window );">Proceeds from exercise of stock options</a></td>
<td class="nump">1,776<span></span>
</td>
<td class="nump">1,010<span></span>
</td>
<td class="nump">4,108<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_NetCashProvidedByUsedInFinancingActivities', window );">Net cash provided by financing activities</a></td>
<td class="nump">29,651<span></span>
</td>
<td class="nump">21,288<span></span>
</td>
<td class="nump">153,243<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect', window );">Increase in cash and cash equivalents during the period</a></td>
<td class="nump">1,866<span></span>
</td>
<td class="num">(2,950)<span></span>
</td>
<td class="nump">122,859<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents', window );">Cash and cash equivalents, beginning of period</a></td>
<td class="nump">149,158<span></span>
</td>
<td class="nump">152,108<span></span>
</td>
<td class="nump">29,249<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents', window );">Cash and cash equivalents, end of period</a></td>
<td class="nump">151,024<span></span>
</td>
<td class="nump">149,158<span></span>
</td>
<td class="nump">152,108<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SupplementalCashFlowInformationAbstract', window );"><strong>Supplemental Cash Flow Information</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_CashPaidForStateAndLocalMinimumIncomeTaxes', window );">Cash paid for state and local minimum income taxes</a></td>
<td class="nump">$ 136<span></span>
</td>
<td class="nump">$ 327<span></span>
</td>
<td class="nump">$ 140<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_CashPaidForStateAndLocalMinimumIncomeTaxes">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_CashPaidForStateAndLocalMinimumIncomeTaxes</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_DeferredGrantIncome">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_DeferredGrantIncome</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_NoncashFinancingRelatedCharges">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_NoncashFinancingRelatedCharges</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of cash and cash equivalents, and cash and cash equivalents restricted to withdrawal or usage. Excludes amount for disposal group and discontinued operations. Cash includes, but is not limited to, currency on hand, demand deposits with banks or financial institutions, and other accounts with general characteristics of demand deposits. Cash equivalents include, but are not limited to, short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 230<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 8<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482913/230-10-50-8<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 230<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 24<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-24<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 4<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-4<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of increase (decrease) in cash and cash equivalents, and cash and cash equivalents restricted to withdrawal or usage; excluding effect from exchange rate change. Cash includes, but is not limited to, currency on hand, demand deposits with banks or financial institutions, and other accounts with general characteristics of demand deposits. Cash equivalents include, but are not limited to, short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 230<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 24<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-24<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 1<br> -SubTopic 230<br> -Topic 830<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481877/830-230-45-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncreaseDecreaseInAccountsPayable">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The increase (decrease) during the reporting period in the aggregate amount of liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received that are used in an entity's business.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (a)<br> -SubTopic 10<br> -Topic 230<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-28<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncreaseDecreaseInAccountsPayable</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncreaseDecreaseInAccruedLiabilities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The increase (decrease) during the reporting period in the aggregate amount of expenses incurred but not yet paid.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (a)<br> -SubTopic 10<br> -Topic 230<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-28<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncreaseDecreaseInAccruedLiabilities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncreaseDecreaseInIncomeTaxesReceivable">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The increase (decrease) during the reporting period in income taxes receivable, which represents the amount due from tax authorities for refunds of overpayments or recoveries of income taxes paid.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (a)<br> -SubTopic 10<br> -Topic 230<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-28<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncreaseDecreaseInIncomeTaxesReceivable</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncreaseDecreaseInOperatingCapitalAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncreaseDecreaseInPrepaidExpense">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The increase (decrease) during the reporting period in the amount of outstanding money paid in advance for goods or services that bring economic benefits for future periods.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (a)<br> -SubTopic 10<br> -Topic 230<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-28<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncreaseDecreaseInPrepaidExpense</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetCashProvidedByUsedInFinancingActivities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of cash inflow (outflow) from financing activities, including discontinued operations. Financing activity cash flows include obtaining resources from owners and providing them with a return on, and a return of, their investment; borrowing money and repaying amounts borrowed, or settling the obligation; and obtaining and paying for other resources obtained from creditors on long-term credit.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 230<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 24<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-24<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetCashProvidedByUsedInFinancingActivities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetCashProvidedByUsedInOperatingActivities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of cash inflow (outflow) from operating activities, including discontinued operations. Operating activity cash flows include transactions, adjustments, and changes in value not defined as investing or financing activities.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 230<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 28<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-28<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 230<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 24<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-24<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 230<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 25<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-25<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetCashProvidedByUsedInOperatingActivities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetIncomeLoss">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480678/235-10-S99-1<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 323<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481687/323-10-50-3<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 825<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482907/825-10-50-28<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 6<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482765/220-10-50-6<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-3<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (b)(2)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-1<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 815<br> -SubTopic 40<br> -Name Accounting Standards Codification<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480175/815-40-65-1<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 8<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-8<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 9<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-9<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-11<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-11<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 4<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-4<br><br>Reference 13: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 946<br> -SubTopic 830<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 10<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480167/946-830-55-10<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 7<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483581/946-220-45-7<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 944<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(18))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483586/944-220-S99-1<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 22<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-22<br><br>Reference 17: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.6-07(9))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-1<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-09(1)(d))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-3<br><br>Reference 19: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(i))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 20: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(ii))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 21: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii)(A))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 22: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iv))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 23: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(5))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 24: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(i))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 25: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(A))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 26: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(B))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 27: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iv))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 28: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(5))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 29: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-30<br><br>Reference 30: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32<br><br>Reference 31: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 60B<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482689/260-10-45-60B<br><br>Reference 32: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 31<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-31<br><br>Reference 33: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32<br><br>Reference 34: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 205<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 7<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483499/205-20-50-7<br><br>Reference 35: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 230<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 28<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-28<br><br>Reference 36: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 1A<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482790/220-10-45-1A<br><br>Reference 37: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 1B<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482790/220-10-45-1B<br><br>Reference 38: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(20))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483621/220-10-S99-2<br><br>Reference 39: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 942<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(22))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483589/942-220-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetIncomeLoss</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PaymentsOfStockIssuanceCosts">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The cash outflow for cost incurred directly with the issuance of an equity security.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 15<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-15<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PaymentsOfStockIssuanceCosts</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ProceedsFromIssuanceOfCommonStock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The cash inflow from the additional capital contribution to the entity.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 14<br> -Subparagraph (a)<br> -SubTopic 10<br> -Topic 230<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-14<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ProceedsFromIssuanceOfCommonStock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ProceedsFromStockOptionsExercised">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of cash inflow from exercise of option under share-based payment arrangement.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 14<br> -Subparagraph (a)<br> -SubTopic 10<br> -Topic 230<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-14<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2A<br> -Subparagraph (a)<br> -SubTopic 10<br> -Topic 718<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2A<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ProceedsFromStockOptionsExercised</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ProceedsFromWarrantExercises">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The cash inflow associated with the amount received from holders exercising their stock warrants.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 230<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 14<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-14<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ProceedsFromWarrantExercises</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensation">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of noncash expense for share-based payment arrangement.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (a)<br> -SubTopic 10<br> -Topic 230<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-28<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensation</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SupplementalCashFlowInformationAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SupplementalCashFlowInformationAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>23
<FILENAME>R7.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649474332448">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Consolidated Statements of Changes in Stockholders' Equity - USD ($)<br> $ in Thousands</strong></div></th>
<th class="th"><div>Common Stock [Member]</div></th>
<th class="th"><div>Additional Paid-in Capital [Member]</div></th>
<th class="th"><div>Retained Earnings [Member]</div></th>
<th class="th"><div>Total</div></th>
</tr>
<tr class="rc">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Beginning balance, value at Sep. 30, 2020</a></td>
<td class="nump">$ 62<span></span>
</td>
<td class="nump">$ 186,852<span></span>
</td>
<td class="num">$ (159,677)<span></span>
</td>
<td class="nump">$ 27,237<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharesOutstanding', window );">Balance at beginning, shares at Sep. 30, 2020</a></td>
<td class="nump">62,045,198<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockRepurchasedDuringPeriodValue', window );">Purchase shares</a></td>
<td class="nump">$ 4<span></span>
</td>
<td class="nump">24,107<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockRepurchasedDuringPeriodShares', window );">Purchase shares, shares</a></td>
<td class="nump">4,007,996<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_CommitmentShares', window );">Commitment shares</a></td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_CommitmentSharesShares', window );">Commitment shares, shares</a></td>
<td class="nump">78,213<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedUnderSalesAgreement', window );">Shares issued under Sales Agreement</a></td>
<td class="nump">$ 6<span></span>
</td>
<td class="nump">79,102<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">79,108<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedUnderSalesAgreementShares', window );">Shares issued under Sales Agreement, shares</a></td>
<td class="nump">5,634,576<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_LessSalesAgreementShareIssueCosts', window );">Less: share issue costs</a></td>
<td class="text"> <span></span>
</td>
<td class="num">(2,438)<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="num">(2,438)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedPursuantToRegisteredDirectOffering', window );">Shares issued pursuant to registered direct offering</a></td>
<td class="nump">$ 2<span></span>
</td>
<td class="nump">49,998<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">50,000<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedPursuantToRegisteredDirectOfferingShares', window );">Shares issued pursuant to registered direct offering, shares</a></td>
<td class="nump">2,380,953<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_LessRegisteredDirectOfferingShareIssueCosts', window );">Less: share issue costs</a></td>
<td class="text"> <span></span>
</td>
<td class="num">(3,097)<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="num">(3,097)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedPursuantToExerciseOfStockOptions', window );">Shares issued pursuant to exercise of stock options</a></td>
<td class="nump">$ 1<span></span>
</td>
<td class="nump">4,107<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">4,108<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedPursuantToExerciseOfStockOptionsShares', window );">Shares issued pursuant to exercise of stock options, shares</a></td>
<td class="nump">1,421,529<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedPusuantToExerciseOfWarrants', window );">Shares issued pursuant to exercise of warrants</a></td>
<td class="text"> <span></span>
</td>
<td class="nump">1,466<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">1,466<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedPusuantToExerciseOfWarrantsShares', window );">Shares issued pusuant to exercise of warrants, shares</a></td>
<td class="nump">350,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue', window );">Share based compensation</a></td>
<td class="text"> <span></span>
</td>
<td class="nump">8,231<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">8,231<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net loss</a></td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="num">(37,909)<span></span>
</td>
<td class="num">(37,909)<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Ending balance, value at Sep. 30, 2021</a></td>
<td class="nump">$ 75<span></span>
</td>
<td class="nump">348,328<span></span>
</td>
<td class="num">(197,586)<span></span>
</td>
<td class="nump">150,817<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharesOutstanding', window );">Balance at ending, shares at Sep. 30, 2021</a></td>
<td class="nump">75,918,465<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedUnderSalesAgreement', window );">Shares issued under Sales Agreement</a></td>
<td class="nump">$ 2<span></span>
</td>
<td class="nump">20,983<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">20,985<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedUnderSalesAgreementShares', window );">Shares issued under Sales Agreement, shares</a></td>
<td class="nump">1,623,813<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_LessSalesAgreementShareIssueCosts', window );">Less: share issue costs</a></td>
<td class="text"> <span></span>
</td>
<td class="num">(723)<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="num">(723)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedPursuantToExerciseOfStockOptions', window );">Shares issued pursuant to exercise of stock options</a></td>
<td class="nump">$ 1<span></span>
</td>
<td class="nump">1,010<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">1,011<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedPursuantToExerciseOfStockOptionsShares', window );">Shares issued pursuant to exercise of stock options, shares</a></td>
<td class="nump">400,537<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue', window );">Share based compensation</a></td>
<td class="text"> <span></span>
</td>
<td class="nump">18,379<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">18,379<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net loss</a></td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="num">(47,978)<span></span>
</td>
<td class="num">(47,978)<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Ending balance, value at Sep. 30, 2022</a></td>
<td class="nump">$ 78<span></span>
</td>
<td class="nump">387,977<span></span>
</td>
<td class="num">(245,564)<span></span>
</td>
<td class="nump">142,491<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharesOutstanding', window );">Balance at ending, shares at Sep. 30, 2022</a></td>
<td class="nump">77,942,815<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares', window );">Shares issued under 2023 purchase agreement Initial Commitment shares</a></td>
<td class="text"> <span></span>
</td>
<td class="nump">845<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">845<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares', window );">Shares issued under 2023 purchase agreement Initial Commitment shares, shares</a></td>
<td class="nump">75,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockRepurchasedDuringPeriodValue', window );">Purchase shares</a></td>
<td class="nump">$ 3<span></span>
</td>
<td class="nump">27,872<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">27,875<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockRepurchasedDuringPeriodShares', window );">Purchase shares, shares</a></td>
<td class="nump">3,275,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_CommitmentShares', window );">Commitment shares</a></td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_CommitmentSharesShares', window );">Commitment shares, shares</a></td>
<td class="nump">13,943<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedPursuantToExerciseOfStockOptions', window );">Shares issued pursuant to exercise of stock options</a></td>
<td class="nump">$ 1<span></span>
</td>
<td class="nump">1,775<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">1,776<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SharesIssuedPursuantToExerciseOfStockOptionsShares', window );">Shares issued pursuant to exercise of stock options, shares</a></td>
<td class="nump">759,753<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue', window );">Share based compensation</a></td>
<td class="text"> <span></span>
</td>
<td class="nump">16,370<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">16,370<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net loss</a></td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="num">(47,505)<span></span>
</td>
<td class="num">(47,505)<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Ending balance, value at Sep. 30, 2023</a></td>
<td class="nump">$ 82<span></span>
</td>
<td class="nump">$ 434,839<span></span>
</td>
<td class="num">$ (293,069)<span></span>
</td>
<td class="nump">$ 141,852<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharesOutstanding', window );">Balance at ending, shares at Sep. 30, 2023</a></td>
<td class="nump">82,066,511<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_CommitmentShares">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_CommitmentShares</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_CommitmentSharesShares">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_CommitmentSharesShares</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_LessRegisteredDirectOfferingShareIssueCosts">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_LessRegisteredDirectOfferingShareIssueCosts</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_LessSalesAgreementShareIssueCosts">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_LessSalesAgreementShareIssueCosts</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_SharesIssuedPursuantToExerciseOfStockOptions">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_SharesIssuedPursuantToExerciseOfStockOptions</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_SharesIssuedPursuantToExerciseOfStockOptionsShares">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_SharesIssuedPursuantToExerciseOfStockOptionsShares</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_SharesIssuedPursuantToRegisteredDirectOffering">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_SharesIssuedPursuantToRegisteredDirectOffering</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_SharesIssuedPursuantToRegisteredDirectOfferingShares">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_SharesIssuedPursuantToRegisteredDirectOfferingShares</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_SharesIssuedPusuantToExerciseOfWarrants">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_SharesIssuedPusuantToExerciseOfWarrants</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_SharesIssuedPusuantToExerciseOfWarrantsShares">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_SharesIssuedPusuantToExerciseOfWarrantsShares</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_SharesIssuedUnderSalesAgreement">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_SharesIssuedUnderSalesAgreement</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_SharesIssuedUnderSalesAgreementShares">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_SharesIssuedUnderSalesAgreementShares</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of increase to additional paid-in capital (APIC) for recognition of cost for award under share-based payment arrangement.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 35<br> -Paragraph 2<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480483/718-10-35-2<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 20<br> -Section 55<br> -Paragraph 13<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481089/718-20-55-13<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 20<br> -Section 55<br> -Paragraph 12<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481089/718-20-55-12<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetIncomeLoss">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480678/235-10-S99-1<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 323<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481687/323-10-50-3<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 825<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482907/825-10-50-28<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 6<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482765/220-10-50-6<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-3<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (b)(2)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-1<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 815<br> -SubTopic 40<br> -Name Accounting Standards Codification<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480175/815-40-65-1<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 8<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-8<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 9<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-9<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-11<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-11<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 250<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 4<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483443/250-10-50-4<br><br>Reference 13: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 946<br> -SubTopic 830<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 10<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480167/946-830-55-10<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 7<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483581/946-220-45-7<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 944<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(18))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483586/944-220-S99-1<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 22<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-22<br><br>Reference 17: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.6-07(9))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-1<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-09(1)(d))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-3<br><br>Reference 19: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(i))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 20: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(ii))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 21: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii)(A))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 22: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iv))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 23: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(5))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1A<br><br>Reference 24: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(i))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 25: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(A))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 26: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(B))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 27: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iv))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 28: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 470<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(5))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480097/470-10-S99-1B<br><br>Reference 29: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-30<br><br>Reference 30: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32<br><br>Reference 31: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 60B<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482689/260-10-45-60B<br><br>Reference 32: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 31<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-31<br><br>Reference 33: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32<br><br>Reference 34: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 205<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 7<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483499/205-20-50-7<br><br>Reference 35: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 230<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 28<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-28<br><br>Reference 36: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 1A<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482790/220-10-45-1A<br><br>Reference 37: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 1B<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482790/220-10-45-1B<br><br>Reference 38: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(20))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483621/220-10-S99-2<br><br>Reference 39: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 942<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(22))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483589/942-220-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetIncomeLoss</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SharesOutstanding">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Number of shares issued which are neither cancelled nor held in the treasury.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SharesOutstanding</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockRepurchasedDuringPeriodShares">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Number of shares that have been repurchased during the period and have not been retired and are not held in treasury. Some state laws may govern the circumstances under which an entity may acquire its own stock and prescribe the accounting treatment therefore. This element is used when state law does not recognize treasury stock.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -SubTopic 10<br> -Topic 505<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481112/505-10-50-2<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 505<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481004/946-505-50-2<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-09(4)(b))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-3<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-03(i)(2))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479886/946-10-S99-3<br><br>Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(28))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 505<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480008/505-10-S99-1<br><br>Reference 7: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockRepurchasedDuringPeriodShares</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockRepurchasedDuringPeriodValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Equity impact of the value of stock that has been repurchased during the period and has not been retired and is not held in treasury. Some state laws may mandate the circumstances under which an entity may acquire its own stock and prescribe the accounting treatment therefore. This element is used when state law does not recognize treasury stock.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -SubTopic 10<br> -Topic 505<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481112/505-10-50-2<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 946<br> -SubTopic 830<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 11<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480167/946-830-55-11<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 205<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 4<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480767/946-205-45-4<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 505<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481004/946-505-50-2<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-09(4)(b))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-3<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(28))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br><br>Reference 7: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 505<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480008/505-10-S99-1<br><br>Reference 8: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockRepurchasedDuringPeriodValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockholdersEquity">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of equity (deficit) attributable to parent. Excludes temporary equity and equity attributable to noncontrolling interest.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 852<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 10<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481372/852-10-55-10<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 946<br> -SubTopic 830<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 12<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480167/946-830-55-12<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.6-04(19))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479617/946-210-S99-1<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.6-05(4))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479617/946-210-S99-2<br><br>Reference 5: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-09(4)(b))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-3<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-09(6))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-3<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-09(7))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-3<br><br>Reference 8: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480678/235-10-S99-1<br><br>Reference 9: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 323<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481687/323-10-50-3<br><br>Reference 10: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 825<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482907/825-10-50-28<br><br>Reference 11: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br><br>Reference 12: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(31))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br><br>Reference 13: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(30))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br><br>Reference 14: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 310<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SAB Topic 4.E)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480418/310-10-S99-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockholdersEquity</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>24
<FILENAME>R8.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649477289312">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Business Description and Basis of Presentation<br></strong></div></th>
<th class="th" colspan="1">12 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2023</div></th></tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract', window );"><strong>Organization, Consolidation and Presentation of Financial Statements [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock', window );">Business Description and Basis of Presentation</a></td>
<td class="text"><p id="xdx_80E_eus-gaap--OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_zzwO6whBvBu3" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
1 	<span id="xdx_827_zzKl0Cvv1eXc">Business Description and Basis of Presentation</span> </b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Business</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Anavex
Life Sciences Corp. (&#8220;Anavex&#8221; or the &#8220;Company&#8221;) is a clinical stage biopharmaceutical company engaged in the
development of differentiated therapeutics by applying precision medicine to central nervous system (&#8220;CNS&#8221;) diseases with
high unmet need. Anavex analyzes genomic data from clinical trials to identify biomarkers, which are used in the analysis of its clinical
trials for the treatment of neurodegenerative and neurodevelopmental diseases.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company&#8217;s lead compound ANAVEX<sup>&#174;</sup>2-73 (blarcamesine) is being developed to treat Alzheimer&#8217;s disease, Parkinson&#8217;s
disease and potentially other central nervous system diseases, including rare diseases, such as Rett syndrome, a rare severe neurological
monogenic disorder caused by mutations in the X-linked gene, methyl-CpG-binding protein 2 (&#8220;MECP2&#8221;).</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Basis
of Presentation </i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">These
consolidated financial statements have been prepared pursuant to the rules and regulations of the Securities and Exchange Commission
(&#8220;SEC&#8221;) and the instructions to Form 10-K and have been prepared under the accounting principles generally accepted in the
United States of America (&#8220;U.S. GAAP&#8221;).</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Liquidity</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">All
of the Company&#8217;s potential drug compounds are in the clinical development stage and the Company cannot be certain that its research
and development efforts will be successful or, if successful, that its potential drug compounds will ever be approved for sales to pharmaceutical
companies or generate commercial revenues. To date, we have not generated any revenues from our operations. The Company expects the business
to continue to experience negative cash flows from operations for the foreseeable future and cannot predict when, if ever, our business
might become profitable.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Management
believes that the current working capital position will be sufficient to meet the Company&#8217;s working capital requirements beyond
the next 12 months after the date that these consolidated financial statements are issued. The process of drug development can be costly,
and the timing and outcomes of clinical trials are uncertain.&#160;The assumptions upon which the Company has based its estimates are
routinely evaluated and may be subject to change.&#160;The actual amount of the Company&#8217;s expenditures will vary depending upon
a number of factors including but not limited to the design, timing and duration of future clinical trials, the progress of the Company&#8217;s
research and development programs and the level of financial resources available. The Company has the ability to adjust its operating
plan spending levels based on the timing of future clinical trials.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Other
than our rights related to the Purchase Agreement (as defined below in Note 5), there can be no assurance that additional financing will
be available to us when needed or, if available, that it can be obtained on commercially reasonable terms. If the Company is not able
to obtain the additional financing on a timely basis, if and when it is needed, it will be forced to delay or scale down some or all
of its research and development activities.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for organization, consolidation and basis of presentation of financial statements disclosure.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480424/946-10-50-1<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480424/946-10-50-2<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 810<br> -Name Accounting Standards Codification<br> -Publisher FASB<br> -URI https://asc.fasb.org//810/tableOfContent<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 205<br> -Name Accounting Standards Codification<br> -Publisher FASB<br> -URI https://asc.fasb.org//205/tableOfContent<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>25
<FILENAME>R9.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649481098320">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Summary of Significant Accounting Policies<br></strong></div></th>
<th class="th" colspan="1">12 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2023</div></th></tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AccountingPoliciesAbstract', window );"><strong>Accounting Policies [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SignificantAccountingPoliciesTextBlock', window );">Summary of Significant Accounting Policies</a></td>
<td class="text"><p id="xdx_809_eus-gaap--SignificantAccountingPoliciesTextBlock_zhJnQIuZqXN" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
2	<span id="xdx_825_z0b09WgWKbRj">Summary of Significant Accounting Policies</span> </b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p id="xdx_848_eus-gaap--UseOfEstimates_z6qiTKflTLI2" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86B_zdIdNWMOYl8g">Use
of Estimates</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
preparation of financial statements in accordance with U.S. GAAP requires management to make estimates and assumptions that affect the
reported amounts of assets and liabilities at the date of the financial statements and the reported amounts of revenue and expenses in
the reporting period. The Company regularly evaluates estimates and assumptions related to accounting for research and development costs,
incentive income receivable, valuation and recoverability of deferred tax assets, stock based compensation, and loss contingencies. The
Company bases its estimates and assumptions on current facts, historical experience, and various other factors that it believes to be
reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and
liabilities and the accrual of costs and expenses that are not readily apparent from other sources. The actual results experienced by
the Company may differ materially and adversely from the Company&#8217;s estimates. To the extent there are material differences between
the estimates and the actual results, future results of operations will be affected.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>







<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>








<p id="xdx_84A_eus-gaap--ConsolidationPolicyTextBlock_z2ffcVZrWlFa" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_867_zBDDP2KxbUlg">Principles
of Consolidation</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">These
consolidated financial statements include the accounts of Anavex Life Sciences Corp. and its wholly-owned subsidiaries, Anavex Australia
Pty Limited (&#8220;Anavex Australia&#8221;), a company incorporated under the laws of Australia, Anavex Germany GmbH, a company incorporated
under the laws of Germany, and Anavex Canada Ltd., a company incorporated under the laws of the Province of Ontario, Canada. All inter-company
transactions and balances have been eliminated.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p id="xdx_842_eus-gaap--CashAndCashEquivalentsPolicyTextBlock_zD2psO58wgqi" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_860_zXnZYnJ3AxH9">Cash
and equivalents</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company considers only those investments which are highly liquid, readily convertible to cash and that mature within three months from
the date of purchase to be cash equivalents.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">Highly
liquid investments that are considered cash equivalents include money market&#160;accounts, money market&#160;funds&#160;and&#160;certificates
of deposit. The carrying value of cash equivalents approximates fair value due to the short-term maturity of these securities. The Company&#8217;s
investment policy allows for investments in domestic money market certificates, certificates of deposit, money market funds, bonds or
commercial papers, and establishes diversification and credit quality requirements and limits investments by maturity and issuer. The
Company currently maintains its investments at one large well known financial institution.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">The
Company maintains its cash in bank deposit accounts which, at times, may exceed federally insured limits. Accounts are guaranteed by
the Federal Deposit Insurance Corporation (FDIC) up to $<span id="xdx_90E_eus-gaap--CashFDICInsuredAmount_iI_c20230930_zOPrmEbs29Na" title="Federal deposit insurance corporation">250,000</span> under current regulations. At September 30, 2023 and 2022, substantially
all of the Company&#8217;s cash balances were in excess of these federally insured limits. The Company mitigates this risk by maintaining
the majority of its cash balances in a large well-known financial institution. The Company has not experienced any losses in such accounts.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p id="xdx_849_eus-gaap--ResearchAndDevelopmentExpensePolicy_znu0D1C47Tij" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_869_zOUCigTgWOAl">Research
and Development Expenses</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development costs are expensed as incurred. These expenses are comprised of the costs of the Company&#8217;s proprietary research
and development efforts, including preclinical studies, clinical trials, manufacturing costs, employee salaries and benefits and stock-based
compensation expense, contract services including external research and development expenses incurred under arrangements with third parties
such as contract research organizations (&#8220;CROs&#8221;), facilities costs, overhead costs and other related expenses. Milestone
payments made by the Company to third parties are expensed when the specific milestone has been achieved. Manufacturing costs are expensed
as incurred in accordance with Accounting Standard Codification (&#8220;ASC&#8221;) 730, Research and Development, as these materials
have no alternative future use outside of their intended use.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Nonrefundable
advance payments for goods or services that will be used or rendered for future research and development activities are deferred and
amortized over the period that the goods are delivered, or the related services are performed, subject to an assessment of recoverability.
The Company makes estimates of costs incurred in relation to external CROs, and clinical site costs. When evaluating the adequacy of
the accrued liabilities, the Company analyzes progress of the trials and studies including the phase or completion of events, invoices
received and contracted costs. Judgments and estimates are made in determining the accrued balances at the end of any reporting period.
Actual results could differ from the Company&#8217;s estimates. The Company&#8217;s historical accrual estimates have not been materially
different from actual costs.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>







<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>








<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">In
addition, the Company incurs expenses in respect of intellectual property costs relating to patents and trademarks. The probability of
success and length of time to develop commercial applications of the drugs subject to the underlying patent and trademark costs is difficult
to determine and numerous risks and uncertainties exist with respect to the timely completion of the development projects. There is no
assurance the drugs subject to the underlying patents and trademarks will ever be successfully commercialized.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Due
to these risks and uncertainties, the patent and trademark costs do not meet the definition of an asset and thus are expensed as incurred
within general and administrative expenses.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p id="xdx_84A_eus-gaap--RevenueRecognitionIncentives_zXLfXylE6t0j" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86F_zOf8tSfJTM19">Research
and Development Incentive Income</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company is eligible to obtain certain research and development tax credits, including, through its wholly owned subsidiary Anavex Australia,
the Australian research and development tax incentive credit (the &#8220;Australia R&amp;D credit&#8221;) through a program administered
through the Australian Tax Office (the &#8220;ATO&#8221;) and AusIndustry, a division of the Australian Government&#8217;s Department
of Industry, Innovation and Science (&#8220;AusIndustry&#8221;). The Australia R&amp;D credit program provides for a cash refund based
on a percentage of eligible research and development activities undertaken in Australia by Anavex Australia. Anavex Australia is also
eligible under the Australia R&amp;D credit program to receive the cash refund for certain research and development expenses incurred
by Anavex Australia outside of Australia, to the extent such expenses are pre-approved by AusIndustry pursuant to an advanced overseas
finding application.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Australia R&amp;D credit program is available to eligible companies with an annual aggregate revenue of less than $20.0 million Australian
during the reimbursable period at a rate of 18.5% above the claimant&#8217;s company tax rate in Australia.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
tax incentives are available on the basis of specific criteria with which the Company must comply. Although the tax incentive may be
administered through the local tax authority, the Company has accounted for the incentives outside of the scope of ASC Topic 740, Income
Taxes (&#8220;ASC 740&#8221;), since the incentives are not linked to the Company&#8217;s taxable income and can be realized regardless
of whether the Company has generated taxable income in the respective jurisdictions.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">With
respect to the Australia R&amp;D credit, as there is no authoritative guidance under GAAP for accounting for grants to for-profit business
entities, the Company accounts for the grant by analogy to IAS20 Accounting for Government Grants and Disclosure of Government Assistance
(&#8220;IAS 20&#8221;). The Company recognizes the Research and Development Incentive income as it incurs costs eligible for reimbursement
under the Australia R&amp;D credit program when it is reasonably assured that the cash incentive will be received, as evidenced through
enrollment in the program and when the applicable conditions under the program have been met. The Company accrues for the amount of cash
refund it expects to receive in relation to research and development expenses outside of Australia only to the extent it has received
advanced approval from AusIndustry, pursuant to an approved advanced overseas finding application.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">In
addition, Anavex Australia and Anavex Canada incur Goods and Services Tax (GST) on certain services provided by local vendors. As a domestic
entity in those jurisdictions, Anavex Australia and Anavex Canada are entitled to a refund of the GST paid. Similarly, Anavex Germany
incurs Value Added Tax (VAT) on certain services provided by local vendors, to which it is entitled to a refund of such VAT paid. The
Company&#8217;s estimate of the amount of cash refund it expects to receive related to GST and VAT incurred is included in Incentive
and tax receivables in the accompanying consolidated balance sheets.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p id="xdx_843_ecustom--LicenseFeesPolicyTextBlock_zbyGkTcneVC" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_867_zUYRjRzpeyi4">License
Fees</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">The
Company expenses amounts paid to acquire licenses associated with products under development when the ultimate recovery of the amounts
paid is uncertain and the technology has no alternative future use when acquired. Acquisitions of technology licenses are charged to
expense or capitalized based on management&#8217;s assessment regarding the ultimate recoverability of the amounts paid and the potential
for alternative future use. The Company has determined that the technological feasibility for its product candidates is reached when
the requisite regulatory approvals are obtained to make the product available for sale.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>







<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"></p>








<p id="xdx_84A_eus-gaap--EarningsPerSharePolicyTextBlock_zCP0CRX2uWKf" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_869_z0KRlrCTQKH4">Basic
and Diluted Loss per Share</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Basic
income/(loss) per common share is computed by dividing net income/(loss) available to common stockholders by the weighted average number
of common shares outstanding during the period. Diluted income/(loss) per common share is computed by dividing net income/(loss) available
to common stockholders by the sum of (1) the weighted-average number of common shares outstanding during the period, (2) the dilutive
effect of the assumed exercise of options and warrants using the treasury stock method and (3) the dilutive effect of other potentially
dilutive securities. For purposes of the diluted net loss per share calculation, options and warrants are potentially dilutive securities
and are excluded from the calculation of diluted net loss per share because their effect would be anti-dilutive.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">As
of September 30, 2023, diluted loss per share excludes <span id="xdx_904_eus-gaap--AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c20221001__20230930_zzmQzTvS2P9b" title="Loss per share for potentially dilutive common shares">14,271,780</span> potentially dilutive common shares (2022 &#8211;<span id="xdx_900_eus-gaap--AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c20211001__20220930_zvFJQdLARASf" title="Loss per share for potentially dilutive common shares">13,329,616</span>; 2021 &#8211;
<span id="xdx_905_eus-gaap--AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c20201001__20210930_zhPkKNvGs2j" title="Loss per share for potentially dilutive common shares">11,540,903</span>) related to outstanding options and warrants, as their effect was anti-dilutive.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p id="xdx_84C_eus-gaap--FairValueOfFinancialInstrumentsPolicy_zsg1xhuLguk9" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_861_z1ynJO0M7YLg">Financial
Instruments</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
book value of the Company&#8217;s financial instruments, consisting of cash and equivalents, incentive and tax receivables, accounts
payable and accrued liabilities approximate their fair value due to the short-term maturity of such instruments. Unless otherwise noted,
it is management&#8217;s opinion that the Company is not exposed to significant interest, currency or credit risks arising from these
financial instruments.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p id="xdx_845_eus-gaap--ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_zzpRJBWkzLGg" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_863_zFNDDXLlBLU7">Foreign
Currency Translation</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
functional currency of the Company is the US dollar. Monetary items denominated in a foreign currency are translated into US dollars
at exchange rates prevailing at the balance sheet date and non-monetary items are translated at exchange rates prevailing when the assets
were acquired, or obligations incurred. Foreign currency denominated expense items are translated at exchange rates prevailing on the
transaction date. Unrealized gains or losses arising from the translations are credited or charged to income in the period in which they
occur.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company has determined that the functional currency of Anavex Australia Pty Limited, Anavex Germany GmbH, and Anavex Canada Ltd. is also
the US dollar.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p id="xdx_847_eus-gaap--SegmentReportingPolicyPolicyTextBlock_zmPlKfcJlDNj" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86A_zRFjDP3i0Wx9">Segment
and Geographic Reporting</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Operating
segments are defined as components of an enterprise for which separate discrete information is available for evaluation by the chief
operating decision maker or decision-making group, in deciding how to allocate resources and in assessing performance. The Company views
its operations and manages its business as one operating segment, which is the business of developing novel therapies for the management
of CNS diseases.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p id="xdx_84C_ecustom--GrantIncomePolicyTextBlock_zRVfCktQIAsj" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_865_z4nGz9Qg9Cfe">Grant
Income</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Grant
income is recognized at the fair value of the grant when it is received, and all substantive conditions have been satisfied. Grants received
from government and other agencies in advance of the specific research and development costs to which they relate are deferred and recognized
in the consolidated statements of operations in the period they are earned, typically when the related research and development costs
are incurred.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>







<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>








<p id="xdx_840_eus-gaap--IncomeTaxPolicyTextBlock_zZy051LYIQye" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86B_zFTWQtNxH2pj">Income
Taxes</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company follows the provisions of ASC 740, which requires the asset and liability method of accounting for income taxes. Under the asset
and liability method, deferred tax assets and liabilities are recognized for the future tax consequences attributable to temporary differences
between the financial statements carrying amounts of existing assets and liabilities and their respective tax bases. Deferred tax assets
and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences
are expected to be recovered or settled.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company follows the provisions of ASC 740 regarding accounting for uncertainty in income taxes. The Company initially recognizes tax
positions in the financial statements when it is more likely than not the position will be sustained upon examination by the tax authorities.
Such tax positions are initially and subsequently measured as the largest amount of tax benefit that is greater than 50% likely of being
realized upon ultimate settlement with the tax authority assuming full knowledge of the position and all relevant facts. Application
requires numerous estimates based on available information. The Company considers many factors when evaluating and estimating its tax
positions and tax benefits, and its recognized tax positions and tax benefits may not accurately anticipate actual outcomes. As additional
information is obtained, there may be a need to periodically adjust the recognized tax positions and tax benefits. These periodic adjustments
may have a material impact on the consolidated statements of operations.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company recognizes interest and penalties related to current income tax expense on the interest income, net line, in the accompanying
consolidated statements of operations. Accrued interest and penalties, if any, are included in accrued liabilities on the consolidated
balance sheets.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p id="xdx_841_eus-gaap--ShareBasedCompensationForfeituresPolicyTextBlock_zTxkzG9e8Qce" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86C_zro2ToXrby56">Stock-based
Compensation</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company accounts for all stock-based payments and awards under the fair value method.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
fair value of all share purchase options and warrants are expensed over their contractual vesting period, or over the expected performance
period for only the portion of awards expected to vest, in the case of milestone-based vesting, with a corresponding increase to additional
paid-in capital.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Compensation
costs for stock-based payments with graded vesting are recognized on a straight-line basis. Stock based compensation expense is adjusted
for actual forfeitures of unvested awards as they occur.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company has granted share purchase option awards that vest upon achievement of certain performance criteria, or milestone-based awards.
The Company estimates an implicit service period for achieving performance criteria for each award and recognizes the resulting fair
value as expense over the implicit service period when it concludes that achieving the performance criteria is probable. The Company
periodically reviews and updates as appropriate its estimates of implicit service periods and conclusions on achieving the performance
criteria. Performance awards vest upon achievement of the performance criteria.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company uses the Black-Scholes option valuation model to calculate the fair value of share purchase options and warrants at the date
of the grant. This model requires the input of subjective assumptions, including the expected price volatility and expected life of each&#160;award.
The Company uses the U.S. Treasury daily treasury yield curve rates for the expected term of the option as the risk-free rate. The expected
term represents the period that options granted are expected to be outstanding using the simplified method. The Company&#8217;s historical
share option exercise experience does not provide sufficient basis for estimating the expected term. Expected volatility is based on
the average of the daily share price changes over the expected term. The Company does not estimate forfeitures and elects to record actual
forfeitures as they occur. The Company has not paid any dividends on its common stock historically, therefore no assumption of dividend
payments is made in the model. These assumptions consist of estimates of future market conditions, which are inherently uncertain, and
therefore, are subject to management&#8217;s judgment. Changes in these assumptions can materially affect the fair value estimates.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>







<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>








<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
purchase price of options or warrants may be paid in cash or, if approved by the Company&#8217;s compensation committee (or in the case
of warrants by the Board of Directors) in advance, &#8220;net settled&#8221; in shares of the Company&#8217;s common stock. In a net
settlement of an option or warrant, the Company does not receive payment of the exercise price from the holder but reduces the number
of shares of common stock issued upon the exercise of the stock option or warrant by the smallest number of whole shares that have an
aggregate fair market value equal to or over the aggregate exercise price for the option shares covered by the option or warrant exercised.
Shares issued pursuant to the exercise of options and warrants are issued from the Company&#8217;s treasury.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p id="xdx_84F_eus-gaap--FairValueMeasurementPolicyPolicyTextBlock_zJIfEwJU8NVi" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86F_z75dfpAXfjJj">Fair
Value Measurements</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Fair
value is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal
or most advantageous market for the asset or liability in an orderly transaction between market participants at the measurement date.
Assets and liabilities that are measured at fair value are reported using a three-level fair value hierarchy that prioritizes the inputs
used to measure fair value. This hierarchy maximizes the use of observable inputs and minimizes the use of unobservable inputs. The three
levels of inputs used to measure fair value are as follows:</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Level
1 - 	quoted prices (unadjusted) in active markets for identical assets or liabilities that the Company has the ability to access at
the measurement date;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Level
2 - observable inputs other than Level 1, quoted prices for similar assets or liabilities in active 		markets, quoted prices for
identical or similar assets and liabilities in markets that are not active, and model-derived prices whose inputs are observable or whose
significant value drivers are observable; and</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Level
3 - 	assets and liabilities whose significant value drivers are unobservable by little or no market activity and that are significant
to the fair value of the assets or liabilities.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">At
September 30, 2023 and 2022, the Company did not have any Level 2 or Level 3 assets or liabilities.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p id="xdx_84A_eus-gaap--NewAccountingPronouncementsPolicyPolicyTextBlock_zLldraoEwC7c" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_864_z3SKDNiOVEng">Recently
Adopted Accounting Pronouncements</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Effective
October 1, 2021, the Company adopted Accounting Standards Update (&#8220;ASU&#8221;) 2019-12, &#8220;Simplifying the Accounting for Income
Taxes (ASC 740)&#8221;, which is intended to simplify various aspects related to accounting for income taxes by removing certain exceptions
to the general principles in Topic 740 and clarifying and amending existing guidance to improve consistent application. There was no
material impact on the Company&#8217;s operations, financial condition, or cash flows.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
October 1, 2022, the Company adopted ASU 2021-10, Annual Disclosure Requirements for Business Entities Receiving Government Assistance
(Topic 832) &#8211; Disclosures by Business Entities about Government Assistance, which requires business entities to disclose information
about transactions with a government that are accounted for by applying a grant or contribution model by analogy. For transactions within
scope, the new standard requires the disclosure of information about the nature of the transaction, including significant terms and conditions,
as well as the amounts and specific financial statement line items affected by the transaction. The disclosure of the Company&#8217;s
research and development tax incentive income and receivable is detailed in Note 4.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>
















<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AccountingPoliciesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AccountingPoliciesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SignificantAccountingPoliciesTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for all significant accounting policies of the reporting entity.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483426/235-10-50-1<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 235<br> -Name Accounting Standards Codification<br> -Publisher FASB<br> -URI https://asc.fasb.org//235/tableOfContent<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SignificantAccountingPoliciesTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>26
<FILENAME>R10.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649480274784">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Accrued Liabilities<br></strong></div></th>
<th class="th" colspan="1">12 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2023</div></th></tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_DisclosureAccruedLiabilitiesAbstract', window );"><strong>Accrued Liabilities</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_AccuredLiabilitiesTextBlock', window );">Accrued Liabilities</a></td>
<td class="text"><p id="xdx_800_ecustom--AccuredLiabilitiesTextBlock_zWiWbayK1Fog" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
3	<span id="xdx_82E_zhZbrFyFkNS2">Accrued Liabilities</span> </b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
principal components of accrued liabilities consist of (in thousands):</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>

<table cellpadding="0" cellspacing="0" id="xdx_88F_eus-gaap--ScheduleOfAccruedLiabilitiesTableTextBlock_pn3n3_zw7Q0sR5wox1" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Accrued Liabilities (Details)">
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span id="xdx_8B9_z9D2IZIcaaxc" style="display: none">Schedule of principal components of accrued liabilities</span></td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td id="xdx_49F_20230930_zOblcHItXB76" style="text-align: center">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td id="xdx_496_20220930_zC7voMSPrPQc" style="text-align: center">&#160;</td>
<td style="text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="7" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30,</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td></tr>
<tr id="xdx_40F_ecustom--AccruedClinicalSiteAndPatientVisitsCosts_iI_maALCz5rZ_zzgKyxye7SBb" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 56%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accrued
clinical site and patient visits costs</span></td>
<td style="width: 8%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 12%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,006</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 8%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 12%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,031</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_403_eus-gaap--AccruedBonusesCurrent_iI_maALCz5rZ_zPPgeMs8YLF3" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accrued
compensation and benefits</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,360</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,298</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40A_ecustom--FixedContractAccruals_iI_maALCz5rZ_zGGMM1w3vkW4" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Fixed
contract accruals</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">38</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">417</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_405_ecustom--MilestoneBasedContractAccruals_iI_maALCz5rZ_zewnh5C4LrUk" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Milestone
based contract accruals</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,267</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">137</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40B_eus-gaap--OtherAccruedLiabilitiesCurrent_iI_maALCz5rZ_z65jJeLLNDBi" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">All
other accrued liabilities</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,624</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,062</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_400_eus-gaap--AccruedLiabilitiesCurrent_iTI_mtALCz5rZ_zK68g3Y0HK82" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 2.5pt 10pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total
accrued liabilities</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7,295</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5,945</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_AccuredLiabilitiesTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_AccuredLiabilitiesTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_DisclosureAccruedLiabilitiesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_DisclosureAccruedLiabilitiesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>27
<FILENAME>R11.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649477241344">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Other Income<br></strong></div></th>
<th class="th" colspan="1">12 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2023</div></th></tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_DisclosureOtherIncomeAbstract', window );"><strong>Other Income</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_OtherIncomeDisclosureTextBlock', window );">Other Income</a></td>
<td class="text"><p id="xdx_804_ecustom--OtherIncomeDisclosureTextBlock_z7ED0CC1PYJ4" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
4	<span id="xdx_820_zezQfDrLEqdi">Other Income</span></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Grant
income</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">During
the year ended September 30, 2023, the Company received $<span id="xdx_906_ecustom--GrantIncome_pn5n6_c20221001__20230930_zIuHWYwmVaId" title="Grant income">0.5</span> million (2022: $<span id="xdx_903_ecustom--GrantIncome_c20211001__20220930_zd1fw8vKH0Bj" title="Grant income">0</span> 2021: $<span id="xdx_905_ecustom--GrantIncome_pn5n6_c20201001__20210930_zKaZ0kl3IiR7" title="Grant income">0.5</span> million) of a $<span id="xdx_903_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20201001__20210930__us-gaap--RelatedPartyTransactionsByRelatedPartyAxis__custom--MichaelJFoxFoundationMember_zUiITfrFOqaa" title="Research and development incentive income">1</span>.0 million research grant awarded
during the year ended September 30, 2021, by the Michael J. Fox Foundation for Parkinson&#8217;s Research. The grant will be used to
fund a clinical trial of the Company&#8217;s lead compound, ANAVEX<sup>&#174;</sup>2-73 (blarcamesine) related to Parkinson&#8217;s disease.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
grant income was deferred when received and amortized to other income as the related research and development expenditures are incurred.
During the year ended September 30, 2023, the Company recognized $<span id="xdx_90D_ecustom--NonOperatingIncomeFromGrant_c20221001__20230930_zlOdEtzkeJL3" title="Non operating income from grant">25,000</span> (2022: $<span id="xdx_903_ecustom--NonOperatingIncomeFromGrant_c20211001__20220930_zkvjDz7v4wHd" title="Non operating income from grant">0</span>; 2021: $<span id="xdx_900_ecustom--NonOperatingIncomeFromGrant_c20201001__20210930_z2o8qeI1rZo4" title="Non operating income from grant">54,100</span>) of this grant on its statements of
operations within grant income. At September 30, 2023 an amount of $<span id="xdx_906_ecustom--DeferredGrantIncome1_pn5n6_c20221001__20230930_zxwtGse5Gk57" title="Deferred grant income">0.9</span> million (2022: $<span id="xdx_90B_ecustom--DeferredGrantIncome1_pn5n6_c20211001__20220930_ztxPyoxVQksl" title="Deferred grant income">0.4</span> million) of this grant is recorded as deferred
grant income, representing the amount of this grant which has not yet been amortized to other income. The Company will recognize this
income on its statements of operations as the related expenditures are incurred to offset the income.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Research
and development incentive income</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development incentive income represents the income earned by Anavex Australia of the Australia R&amp;D credit. This cash incentive
is received by Anavex Australia, upon filing of a claim in connection with Anavex Australia&#8217;s annual income tax return.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">During
the year ended September 30, 2023, the Company recorded research and development incentive income of $<span id="xdx_900_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20221001__20230930_zID3NUwQhl64" title="Research and development incentive income">2.7</span> million (AUD <span id="xdx_906_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20221001__20230930__srt--CurrencyAxis__currency--AUD_zU8tfJYJcOWc" title="Research and development incentive income">4.1</span> million) (2022:
$<span id="xdx_900_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20211001__20220930_z9qs1g3PLpXc" title="Research and development incentive income">3.3</span> million (AUD <span id="xdx_908_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20211001__20220930__srt--CurrencyAxis__currency--AUD_zXzB35mMhmpl" title="Research and development incentive income">4.5</span> million); 2021: $<span id="xdx_90B_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20201001__20210930_zl46LELTKP84" title="Research and development incentive income">4.5</span> million (AUD <span id="xdx_90F_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20201001__20210930__srt--CurrencyAxis__currency--AUD_zJ25LJXGoyc5" title="Research and development incentive income">6.1</span> million)) in respect of the Australia R&amp;D credit for eligible research
and development expenses incurred during the year. This amount is included within Other income (expense) on the consolidated statements
of operations.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">At
September 30, 2023, Incentive and tax receivables includes $<span id="xdx_904_eus-gaap--OtherReceivables_iI_pn5n6_c20230930_zzdtGDxecS6i" title="Incentive and tax receivables">2.5</span> million (AUD <span id="xdx_903_eus-gaap--OtherReceivables_iI_pn5n6_c20230930__srt--CurrencyAxis__currency--AUD_z33if1GWYJ43" title="Incentive and tax receivables">3.9</span> million) (2022: $<span id="xdx_906_eus-gaap--OtherReceivables_iI_pn5n6_c20220930_zl6nET4zhSgf" title="Incentive and tax receivables">2.9</span> million (AUD <span id="xdx_908_eus-gaap--OtherReceivables_iI_pn5n6_c20220930__srt--CurrencyAxis__currency--AUD_z4Fmw8vKgvI2" title="Incentive and tax receivables">4.5</span> million) relating
to Australia R&amp;D credits earned during the year that are expected to be reimbursed upon filing of the Company&#8217;s annual claim
under this program.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Australia R&amp;D credit program is a self-assess program whereby the Company must assess its eligibility each year to determine (i)
if the entity is eligible (ii) if the specific R&amp;D activities are eligible and (iii) if the individual R&amp;D expenditures have
nexus to such R&amp;D activities. The Company evaluates its eligibility under the tax incentive program as of each balance sheet date
based on the most current and relevant data available. Anavex Australia is able to continue to claim the R&amp;D tax incentive for as
long as it remains eligible and continues to incur eligible research and development expenditures.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>







<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"></p>








<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Although
the Company believes that it has complied with all the relevant conditions of eligibility under the program for all periods claimed,
the ATO has the right to review the Company&#8217;s qualifying programs and related expenditures for a period of four years. If such
a review were to occur, the ATO may have different interpretations of certain eligibility requirements. If the ATO disagreed with the
Company&#8217;s assessments and any related subsequent appeals, it could require adjustment to and repayment of current or previous years&#8217;
claims already received. Additionally, if the Company was unable to demonstrate a reasonably arguable position taken on such claims,
the ATO could also assess penalties and interest on such adjustment.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Currently,
the Company&#8217;s tax incentive claims from 2019 to 2022 are open to potential review by the ATO. Additionally, the period open for
review is indefinite if the ATO suspects fraud. The Company has not provided any allowance for any such potential adjustments, should
they occur in the future.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_DisclosureOtherIncomeAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_DisclosureOtherIncomeAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_OtherIncomeDisclosureTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_OtherIncomeDisclosureTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>28
<FILENAME>R12.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649567306544">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Equity Offerings<br></strong></div></th>
<th class="th" colspan="1">12 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2023</div></th></tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_DisclosureEquityOfferingsAbstract', window );"><strong>Equity Offerings</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_EquityOfferingTextBlock', window );">Equity Offerings</a></td>
<td class="text"><p id="xdx_804_ecustom--EquityOfferingTextBlock_zb4TDoN2phd4" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
5	<span id="xdx_820_zyNNCA0EwmA4">Equity Offerings</span></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Common
Stock</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common
shares are voting and are entitled to dividends as declared at the discretion of the Board of Directors.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Preferred
Stock</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company&#8217;s Board of Directors&#160;(the &#8220;Board&#8221;)&#160;has the authority to issue preferred stock in one or more series
and to fix the rights, preferences, privileges, restrictions and the number of shares constituting any series or the designation of the
series.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Registered
Direct Offering</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
June 22, 2021, the Company and Deep Track Capital entered into a securities purchase agreement pursuant to which the Company sold to
Deep Track Capital an aggregate of <span id="xdx_90D_eus-gaap--SaleOfStockNumberOfSharesIssuedInTransaction_pip0_c20210621__20210622__us-gaap--TypeOfArrangementAxis__custom--SecuritiesPurchaseAgreementMember_zc6y134LHS88" title="Sale of stock, shares">2,380,953</span> shares of common stock at $<span id="xdx_902_eus-gaap--SaleOfStockPricePerShare_iI_pip0_c20210622__us-gaap--TypeOfArrangementAxis__custom--SecuritiesPurchaseAgreementMember_zW7JGKcfhi15" title="Sale of stock, per share">21</span> per share in a registered direct offering, for gross proceeds
of $<span id="xdx_909_eus-gaap--SaleOfStockConsiderationReceivedOnTransaction_pn6n6_c20210621__20210622__us-gaap--TypeOfArrangementAxis__custom--SecuritiesPurchaseAgreementMember_zpiUI66Lxw1a" title="Gross proceeds from sale of stock">50</span> million. Net proceeds of the offering were $<span id="xdx_90E_eus-gaap--ProceedsFromIssuanceInitialPublicOffering_c20210621__20210622__us-gaap--TypeOfArrangementAxis__custom--SecuritiesPurchaseAgreementMember_zUSWYrXZ3X09" title="Proceed from offering">46,902,981</span> after deducting offering fees and expenses.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Sales
Agreement</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company entered into a Controlled Equity Offering Sales Agreement on July 6, 2018, which was amended and restated on May 1, 2020 (the
&#8220;Sales Agreement&#8221;) with Cantor Fitzgerald&#160;&amp; Co. and SVB Leerink LLC (together the &#8220;Sales Agents&#8221;), pursuant
to which the Company may offer and sell shares of common stock registered under an effective registration statement from time to time
through the Sales Agents (the &#8220;Offering&#8221;).</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Upon
delivery of a placement notice based on the Company&#8217;s instructions and subject to the terms and conditions of the Sales Agreement,
the Sales Agents may sell the Shares by methods deemed to be an &#8220;at the market offering&#8221; offering, in negotiated transactions
at market prices prevailing at the time of sale or at prices related to such prevailing market prices, or by any other method permitted
by law, including negotiated transactions, subject to the prior written consent of the Company. The Company is not obligated to make
any sales of Shares under the Sales Agreement. The Company or Sales Agents may suspend or terminate the offering of Shares upon notice
to the other party, subject to certain conditions. The Sales Agents will act as agent on a commercially reasonable efforts basis consistent
with their normal trading and sales practices and applicable state and federal law, rules&#160;and regulations and the rules&#160;of
Nasdaq.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company has agreed to pay the Sales Agents commissions for their services of up to <span id="xdx_903_ecustom--PercentageOfGrossProceedsFromSales_pip0_dp_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zlabhXU0ZUv5" title="Percentage of gross proceeds from sales">3.0</span>% of the gross proceeds from the sale of the Shares
pursuant to the Sales Agreement. The Company also agreed to provide the Sales Agents with customary indemnification and contribution
rights. During the year ended September 30, 2023, <span id="xdx_90A_eus-gaap--SaleOfStockNumberOfSharesIssuedInTransaction_pip0_do_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zQ3IqyGRUkTa" title="Number of common stock sold, shares">no</span> shares were sold pursuant to the Offering. During the year ended September 30, 2022,
<span id="xdx_906_eus-gaap--SaleOfStockNumberOfSharesIssuedInTransaction_pip0_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zjhhMExQvuvh" title="Number of common stock sold, shares">1,623,813</span> shares were sold pursuant to the Offering for gross proceeds of $<span id="xdx_900_eus-gaap--SaleOfStockConsiderationReceivedPerTransaction_pn6n6_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zW5D1KhaZJV1" title="Number of common stock sold, value">21</span>.0 million (net proceeds of $<span id="xdx_90A_eus-gaap--ProceedsFromIssuanceInitialPublicOffering_pn5n6_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zPbB3LyZ0Sqi" title="Net proceed">20.3</span> million after deducting
offering expenses) (2021: <span id="xdx_908_eus-gaap--SaleOfStockNumberOfSharesIssuedInTransaction_pip0_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zMmT4jfnutZ5" title="Number of common stock sold">5,634,576</span> shares were sold for gross proceeds of $<span id="xdx_90C_ecustom--SoldForGrossProceedsAmount_pn5n6_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zBr3s8zoCXxc" title="Sold for gross proceeds amount">79.1</span> million, net proceeds of $<span id="xdx_90E_eus-gaap--ProceedsFromIssuanceInitialPublicOffering_pn5n6_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zI1CybzBzu9d" title="Net proceed">76.7</span> million). At September
30, 2023, an amount of $<span id="xdx_90F_ecustom--SalesOfAgreementAmount_iI_pn5n6_c20230930_zosJik8ijhB" title="Sales of agreement amount">142.4</span> million (2022: $<span id="xdx_907_ecustom--SalesOfAgreementAmount_iI_pn5n6_c20220930_zHv3V2kjN8Xe" title="Sales of agreement amount">142.4</span> million) was registered pursuant to an effective registration statement. The Company
currently does not have access to sell shares of common stock under the Sales Agreement.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>







<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>








<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>2023
Purchase Agreement</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
February 3, 2023, the Company entered into a $150.0 million purchase agreement (the &#8220;2023 Purchase Agreement&#8221;) with Lincoln
Park Capital Fund, LLC (&#8220;Lincoln Park&#8221;), pursuant to which the Company has the right to sell and issue to Lincoln Park, and
Lincoln Park is obligated to purchase, up to $<span id="xdx_90F_ecustom--ValueOfSharesObligatedToPurchase_pn6n6_c20230202__20230203__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zcxkDCBcwoBl" title="Value of shares obligated to purchase">150</span>.0 million in value of its shares of common stock from time to time over a three-year
period until February 3, 2026.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">In
consideration for entering into the 2023 Purchase Agreement, the Company issued to Lincoln Park <span id="xdx_909_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20230202__20230203__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_z8aVciu8dKa4" title="Share issued for offering, shares">75,000</span> shares of common stock as a commitment
fee (the &#8220;initial commitment shares&#8221;) and agreed to issue up to an additional <span id="xdx_905_ecustom--NumberOfSharesObligatedToPurchaseProrataBasic_pip0_c20230202__20230203__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zDmvYDmRpIR4" title="Pro rata basic number of shares obligated to purchase">75,000</span> shares pro rata, when and if, Lincoln
Park purchased, at the Company&#8217;s discretion, the $<span id="xdx_904_eus-gaap--ProceedsFromIssuanceOrSaleOfEquity_pn6n6_c20230202__20230203__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zWtvzgAbQT47" title="Proceeds from issuance or sale of equity">150</span>.0 million aggregate commitment. The Company determined the fair value of
the initial commitment shares was $<span id="xdx_90C_ecustom--FairValueOfInitialCommitment_iI_pn5n6_c20230930_z4HQFCRySBs8" title="Fair value of the initial commitment">0.8</span> million with reference to the closing price of the Company&#8217;s shares on the Purchase Agreement
date. In addition, the Company incurred third party expenses of $<span id="xdx_900_ecustom--IncurredExpenses_iI_pn5n6_c20230930_zqBMreamcBK4" title="Incurred expenses">0.1</span> million in connection with entering into the Purchase Agreement.
These amounts were expensed to other financing expense on the statements of operations during the year ended September 30, 2023.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">During
the year ended September 30, 2023, the Company issued to Lincoln Park an aggregate of <span id="xdx_906_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockIncludingCommitmentSharesMember_zjTYlplPSAh2" title="Number of shares issued, shares">3,288,943</span> (2022: <span id="xdx_907_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockIncludingCommitmentSharesMember_z6LOpIPL6A33" title="Number of shares issued, shares">0</span>) shares of common stock under
the 2023 Purchase Agreement, including <span id="xdx_902_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockExcludingCommitmentSharesMember_zKHtPnsEnjXa" title="Number of shares issued, shares">3,275,000</span> (2022: <span id="xdx_90A_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockExcludingCommitmentSharesMember_zYwnI6VFVwnc" title="Number of shares issued, shares">0</span>) shares of common stock for aggregate proceeds of $<span id="xdx_90D_eus-gaap--StockIssuedDuringPeriodValueNewIssues_pn5n6_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zzlbzAywYWSf" title="Number of shares issued, value">27.9</span> million (2022: $<span id="xdx_904_eus-gaap--StockIssuedDuringPeriodValueNewIssues_pn5n6_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zaJiVBhsgBWg" title="Number of shares issued, value">0</span>)
and&#160;<span id="xdx_907_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommitmentSharesMember_znaRV435uB97" title="Number of shares issued, shares">13,943</span>&#160;(2022:&#160;<span id="xdx_900_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommitmentSharesMember_znqFy6tpohz1" title="Number of shares issued, shares">0</span>) commitment shares.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">At
September 30, 2023, an amount of $<span id="xdx_903_eus-gaap--StockIssuedDuringPeriodValueOther_pn5n6_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zO9v6gY7XRR7" title="Amount of shares remain available">122.1</span> million remained available under the 2023 Purchase Agreement.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>2019
Purchase Agreement</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
June 7, 2019, the Company entered into a $50.0 million purchase agreement (the &#8220;2019 Purchase Agreement&#8221;) with Lincoln Park,
as amended on July 1, 2020, pursuant to which the Company had the right to sell and issue to Lincoln Park, and Lincoln Park was obligated
to purchase, up to $<span id="xdx_90E_ecustom--ValueOfSharesObligatedToPurchase_pn6n6_c20230202__20230203__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zcrfomPkYdqb" title="Value of shares obligated to purchase">50</span>.0 million in value of its shares of common stock from time to time over a three-year period until July 1, 2022.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">During
the year ended September 30, 2023 and 2022, the Company did not issue any shares to Lincoln Park under the 2019 Purchase Agreement.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">During
the year ended September 30, 2021, the Company issued to Lincoln Park an aggregate of <span id="xdx_903_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockIncludingCommitmentSharesMember_znOth4NjnOii" title="Number of shares issued, shares">4,086,209</span> shares of common stock under the 2019
Purchase Agreement, including <span id="xdx_901_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockExcludingCommitmentSharesMember_zT70L5cMjiab" title="Number of shares issued, shares">4,007,996</span> shares of common stock for an aggregate purchase price of $<span id="xdx_905_eus-gaap--StockIssuedDuringPeriodValueNewIssues_pn5n6_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__us-gaap--CommonStockMember_zhdeqeVovxv4" title="Number of shares issued, value">24.1</span> million and <span id="xdx_905_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommitmentSharesMember_zNPOHsOEFG8g" title="Number of shares issued, shares">78,213</span> commitment
shares.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">At
September 30, 2023 and 2022, <span id="xdx_907_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_do_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zxh1eYR61Yfc" title="Number of shares issued, shares"><span id="xdx_901_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_do_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zTTuLXokmTC5" title="Number of shares issued, shares">no</span></span> shares remained available for issuance under the 2019 Purchase Agreement.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_DisclosureEquityOfferingsAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_DisclosureEquityOfferingsAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_EquityOfferingTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_EquityOfferingTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>29
<FILENAME>R13.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649567306544">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Commitments and Contingencies<br></strong></div></th>
<th class="th" colspan="1">12 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2023</div></th></tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CommitmentsAndContingenciesDisclosureAbstract', window );"><strong>Commitments and Contingencies Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CommitmentsDisclosureTextBlock', window );">Commitments and Contingencies</a></td>
<td class="text"><p id="xdx_802_eus-gaap--CommitmentsDisclosureTextBlock_zE2pkYALuI52" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
6	<span id="xdx_82F_zcntuv9Owit">Commitments and Contingencies</span></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Lease</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">The
Company leases office space under an operating lease with an initial term of <span id="xdx_909_eus-gaap--OperatingLeaseWeightedAverageRemainingLeaseTerm1_iI_dtM_c20230930_zGILsxUCfssh" title="Operating lease term">12</span> months or less. Under the terms of the office lease,
the Company is required to pay its proportionate share of operating costs. </span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">The
operating lease costs were as follows (in thousands):</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>







<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"></p>







<table cellpadding="0" cellspacing="0" id="xdx_892_eus-gaap--LeaseCostTableTextBlock_pn3n3_zebQe0HUsBil" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse" summary="xdx: Disclosure - Commitments and Contingencies (Details)">
  <tr style="vertical-align: bottom">
    <td style="text-align: left"><span id="xdx_8BD_zRdYsDhim6L" style="display: none">Schedule of operating lease costs</span></td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_497_20221001__20230930_zoFz6uIyoz5h" style="text-align: center">&#160;</td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_497_20211001__20220930_zWLZSQljBpKc" style="text-align: center">&#160;</td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_496_20201001__20210930_zMlBeHRgn1ej" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="11" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>September
    30,</b></span></td></tr>
  <tr style="vertical-align: bottom">
    <td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2023</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2022</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2021</b></span></td></tr>
  <tr id="xdx_400_eus-gaap--OperatingLeaseCost_zNr7fwUnSpa" style="vertical-align: bottom; background-color: #CCEEFF">
    <td style="width: 55%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Operating lease costs</span></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">118</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">73</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">131</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  </table>

<p id="xdx_8A5_zYMkVcWgWcFj" style="margin-top: 0; margin-bottom: 0">&#160;<span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Employee
401(k) Benefit Plan</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">The
Company has a defined-contribution savings plan under Section 401(k) of the Internal Revenue Code. The plan covers all United States
based employees. United States based employees eligible to participate in the plan may contribute up to the current statutory limits
under the Internal Revenue Service regulations. The 401(k) plan permits the Company to make additional matching contributions on behalf
of contributing employees. </span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">During
the year ended September 30, 2023, the Company made matching contributions under the 401(k) plan as follows (in thousands):</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 9pt Sans-Serif; margin: 0; color: Red"></p>

<table cellpadding="0" cellspacing="0" id="xdx_89F_eus-gaap--DefinedContributionPlanDisclosuresTableTextBlock_pn3n3_z6GAoPcUR2E" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse" summary="xdx: Disclosure - Commitments and Contingencies (Details 1)">
  <tr style="vertical-align: bottom">
    <td style="text-align: left"><span id="xdx_8B6_zNZ0ix4JlNLb" style="display: none">Schedule of contributions under the  plan</span></td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_497_20221001__20230930_zA0qushBeCO8" style="text-align: center">&#160;</td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_497_20211001__20220930_zj5JX4iHu8rg" style="text-align: center">&#160;</td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_496_20201001__20210930_zJ6NvaX8QTVe" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="11" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>September
    30,</b></span></td></tr>
  <tr style="vertical-align: bottom">
    <td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2023</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2022</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2021</b></span></td></tr>
  <tr id="xdx_40C_eus-gaap--PensionContributions_zAjEbuXkDcDj" style="vertical-align: bottom; background-color: #CCEEFF">
    <td style="width: 55%"><p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Contributions
                           to 401(k) plan</span></p></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">232</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">158</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">129</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  </table>
<p style="font: 9pt Sans-Serif; margin: 0; color: Red"></p>

<p id="xdx_8AB_zFJSuoNaYAbd" style="font: 10pt Times New Roman, Times, Serif; margin: 0; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Litigation</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; background-color: white">The
Company is subject to claims and legal proceedings that arise in the ordinary course of business. Such matters are inherently uncertain,
and there can be no guarantee that the outcome of any such matter will be decided favorably to the Company or that the resolution of
any such matter will not have a material adverse effect upon the Company&#8217;s consolidated financial statements. The Company does
not believe that any of such pending claims and legal proceedings will have a material adverse effect on its consolidated financial statements.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Share
Purchase Warrants</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">At
September 30, 2023 and 2022, the Company had <span id="xdx_905_eus-gaap--ClassOfWarrantOrRightOutstanding_iI_pip0_c20230930_zU9Dso551HI8" title="Warrants outstanding"><span id="xdx_909_eus-gaap--ClassOfWarrantOrRightOutstanding_iI_pip0_c20220930_zaTuvrBJTgF3" title="Warrants outstanding">160,000</span></span> warrants outstanding at a weighted average exercise price of $<span id="xdx_909_ecustom--WarrantsOutstandingWeightedAverageExercise_iI_pip0_c20230930_z3kK5IwtA6el" title="Warrants outstanding weighted average exercise price"><span id="xdx_907_ecustom--WarrantsOutstandingWeightedAverageExercise_iI_pip0_c20220930_z5jtuo1qpm66" title="Warrants outstanding weighted average exercise price">3.72</span></span> as follows:</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<table cellpadding="0" cellspacing="0" id="xdx_89E_ecustom--ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock_zKmN5o46PFt7" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 2)">
<tr style="vertical-align: bottom">
<td colspan="3" style="text-align: left"><span id="xdx_8B6_zdQIUyosHM7i" style="display: none">Schedule of share purchase warrants outstanding</span></td>
<td style="text-align: center">&#160;</td>
<td colspan="3" style="text-align: center">&#160;</td>
<td style="text-align: center">&#160;</td>
<td colspan="3" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Number</span></td>
<td style="text-align: center; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Exercise Price</span></td>
<td style="text-align: center; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Expiry Date</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants1Member_z7DIAed1ljy5" style="width: 26%; text-align: right" title="Number of warrants outstanding"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">150,000</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 8%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants1Member_zSEBrQgKsBAa" style="width: 26%; text-align: right" title="Exercise Price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.17</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 8%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 26%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_906_eus-gaap--WarrantsAndRightsOutstandingMaturityDate_iI_dd_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants1Member_z4XXQCR7NqKd" title="Expiry Date">May 6, 2024</span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants2Member_zek8ir0OxIK2" style="border-bottom: Black 1pt solid; text-align: right" title="Number of warrants outstanding"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">10,000</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants2Member_zckHC5eaRJ0f" style="border-bottom: Black 1pt solid; text-align: right" title="Exercise Price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">12.00</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_903_eus-gaap--WarrantsAndRightsOutstandingMaturityDate_iI_dd_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants2Member_zCjIeYOFUu0j" title="Expiry Date">April 21, 2026</span></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_iI_pip0_c20230930_z1GBMONfXrj9" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of warrants outstanding"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">160,000</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; text-align: right"></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 12pt Times New Roman, Times, Serif; padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 12pt Times New Roman, Times, Serif; padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font: 12pt Times New Roman, Times, Serif; text-align: right"></td>
<td style="font: 12pt Times New Roman, Times, Serif; padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



<p id="xdx_8A9_znw7vZXUMsdd" style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 42.55pt; text-align: left; text-indent: -0.8pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>Stock&#8211;based
Compensation Plan</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>2015
Stock Option Plan</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
September 18, 2015, the Company&#8217;s board of directors approved a 2015 Omnibus Incentive Plan (the &#8220;2015 Plan&#8221;), which
provided for the grant of stock options and restricted stock awards to directors, officers, employees and consultants of the Company.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
maximum number of our common shares reserved for issue under the plan was <span id="xdx_90D_eus-gaap--CommonStockCapitalSharesReservedForFutureIssuance_iI_pip0_c20230930__us-gaap--PlanNameAxis__custom--StockOptionPlan2015Member_zZgMGE32sSjk" title="Maximum number of common shares reserved for future issuance">6,050,553</span> shares, subject to adjustment in the event of a change
of the Company&#8217;s capitalization.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;<b><i>&#160;</i></b></span></p>





<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span><b></b></p>









<p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>2019
Stock Option Plan</i></b></span></span></p>

<p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
January 15, 2019, the Board approved the 2019 Omnibus Incentive Plan (the &#8220;2019 Plan&#8221;), which provides for the grant of stock
options and restricted stock awards to directors, officers, employees, consultants and advisors of the Company.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
maximum number of our common shares reserved for issue under the plan was <span id="xdx_904_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_pip0_c20221001__20230930__us-gaap--PlanNameAxis__custom--StockOptionPlan2019Member_zE2xKSnfxfMj" title="Additional shares of common stock available for issuance">6,000,000</span> shares, subject to adjustment in the event of a change
of the Company&#8217;s capitalization.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">During
the year ended September 30, 2022, <span id="xdx_90D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod_pip0_c20211001__20220930__us-gaap--PlanNameAxis__custom--StockOptionPlan2022Member_zPiZBJkKUDba" title="Option granted">406,453</span> options previously available under the 2019 Plan and the 2015 Plan became available under
the 2022 Plan (as defined below).</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>2022
Stock Option Plan</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
March 25, 2022, the Board approved the 2022 Omnibus Incentive Plan (the &#8220;2022 Plan&#8221;). The 2022 Plan was approved by stockholders
on May 24, 2022. Under the terms of the 2022 Plan, <span id="xdx_908_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_pip0_c20220324__20220325__us-gaap--PlanNameAxis__custom--StockOptionPlan2022Member_zCVPF6lGfzz6" title="Additional shares of common stock available for issuance">10,000,000</span> additional shares of Common Stock will be available for issuance under
the plan, in addition to the shares available under the 2019 Plan and the 2015 Plan. Any awards outstanding under a previous stock option
plan will remain subject to and be paid under such plan, and any shares subject to outstanding awards under a previous plan that subsequently
cease to be subject to such awards (other than by reason of settlement of the awards in shares) will automatically become available for
issuance under the 2022 Plan.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
2022 Plan provides that it may be administered by the Board, or the Board may delegate such responsibility to a committee. The exercise
price will be determined by the Board at the time of grant shall be at least equal to the fair market value on such date. If the grantee
is a 10% stockholder on the grant date, then the exercise price shall not be less than 110% of fair market value of the Company&#8217;s
shares of common stock on the grant date. Stock options may be granted under the 2022 Plan for an exercise period of up to ten years
from the date of grant of the option or such lesser periods as may be determined by the Board, subject to earlier termination in accordance
with the terms of the 2022 Plan. At September 30, 2023, <span id="xdx_904_ecustom--OptionIssued_pip0_c20221001__20230930_zECMzajbkxMi" title="Option issued">3,849,917</span> options had been issued under the 2022 Plan and <span id="xdx_900_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_iI_pip0_c20230930__us-gaap--PlanNameAxis__custom--StockOptionPlan2022Member_zT6pYBZ4Zee1" title="Option available issue">6,661,535</span> options were
available for issue under the 2022 Plan, subject to stockholder approval.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
following summarizes information about stock option activity during the years ended September 30, 2023 and 2022:</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<table cellpadding="0" cellspacing="0" id="xdx_890_eus-gaap--ScheduleOfStockOptionsRollForwardTableTextBlock_zahdwjh2ktsa" style="font: 9.5pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 3)">
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span id="xdx_8B4_zBRZ0wob6U9d" style="display: none">Schedule of stock option activity</span></td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted Average</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Average Grant</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Aggregate intrinsic</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Number of</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Exercise Price</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Date Fair Value</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">value</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Options</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">($)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">($)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">($)</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 18%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Outstanding,
September 30, 2021</span></td>
<td style="width: 3%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iS_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zaQEDt8Geqwg" style="width: 16%; text-align: right" title="Number of options, Outstanding beginning balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">11,330,903</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 3%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iS_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zvh9J0z6rNSg" style="width: 16%; text-align: right" title="Weighted average exercise price, Outstanding beginning balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.74</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 3%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_iS_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zm8JuTSr9WZg" style="width: 15%; text-align: right" title="Weighted average grant date fair value, Outstanding beginning balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0768">&#8212;</span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 3%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_iS_pp0p0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zMVx9451Ez4i" style="width: 15%; text-align: right" title="Aggregate intrinsic value, Outstanding beginning balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">140,132,451</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Granted</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zYDHLx1xNqd" style="text-align: right" title="Number of options, Granted"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,358,000</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_za6WMoclHJt6" style="text-align: right" title="Weighted average exercise price, Granted"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">10.13</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z12ur8IugGNa" style="text-align: right" title="Weighted average grant date fair value, Granted"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7.07</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Forfeited</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_iN_pip0_di_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zzqgqYLwD0x8" style="text-align: right" title="Number of options, Forfeited"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(118,750</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98F_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zz0JNU8yhYOi" style="text-align: right" title="Weighted average exercise price, Forfeited"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.86</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zd5Dfy6k0HWb" style="text-align: right" title="Weighted average grant date fair value, Forfeited"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.23</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Exercised</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--StockIssuedDuringPeriodSharesStockOptionsExercised_iN_pip0_di_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zLVBhCdfo3v2" style="border-bottom: Black 1pt solid; text-align: right" title="Number of options, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(400,537</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zNtv4tKDm84l" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.52</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zyXGXeuunFo" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average grant date fair value, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1.88</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_pp0p0" style="border-bottom: Black 1pt solid; text-align: right" title="Aggregate intrinsic value, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">4,201,015</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Outstanding,
September 30, 2022</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_983_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iS_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zF1F2l3FFbvl" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of options, Outstanding beginning balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">13,169,616</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iS_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zDoB5pRDMJR8" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price, Outstanding beginning balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.61</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_iS_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zP01qsGKaijj" style="border-bottom: Black 2.5pt double; font: normal 10pt Times New Roman, Times, Serif; text-align: right" title="Weighted average grant date fair value, Outstanding beginning balance"><span style="font: normal 10pt Times New Roman, Times, Serif">4.96</span></td>
<td style="padding-bottom: 2.5pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_iS_pp0p0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zoFSMXIeupJ3" style="border-bottom: Black 2.5pt double; text-align: right" title="Aggregate intrinsic value, Outstanding beginning balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">62,267,309</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Granted</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zdGzYZ6nAJ19" style="text-align: right" title="Number of options, Granted"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,959,000</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zZhiagjQKbJd" style="text-align: right" title="Weighted average exercise price, Granted"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">9.30</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_ziClWNBA0fig" style="text-align: right" title="Weighted average grant date fair value, Granted"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.60</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Expired</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Exercised</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_981_eus-gaap--StockIssuedDuringPeriodSharesStockOptionsExercised_iN_pip0_di_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zlKT4O9ITNx2" style="text-align: right" title="Number of options, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(759,753</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zjRxv8zRZ3s6" style="text-align: right" title="Weighted average exercise price, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.34</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_987_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z3bIctfsRpu9" style="text-align: right" title="Weighted average grant date fair value, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">0.95</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_983_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_pp0p0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zumLJJKYvL95" style="text-align: right" title="Aggregate intrinsic value, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">4,629,026</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Forfeited</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_iN_pip0_di_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zcgXAyqtdxn7" style="text-align: right" title="Number of options, Forfeited"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(257,083</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z189xmJSdqYh" style="text-align: right" title="Weighted average exercise price, Forfeited"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">12.00</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98E_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zPz67mlunnO8" style="text-align: right" title="Weighted average grant date fair value, Forfeited"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.74</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Cancelled</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Outstanding,
September 30, 2023</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iE_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zwxfgYOA6xzc" style="border-bottom: Black 1pt solid; text-align: right" title="Number of options, Outstanding ending balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">14,111,780</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iE_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zDKIrfhkqrwi" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price, Outstanding ending balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7.12</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_iE_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z8QNfw1Q0kMg" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average grant date fair value,  Outstanding ending balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.27</span></td>
<td style="padding-bottom: 1pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_iE_pp0p0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zevpgIbVICHg" style="border-bottom: Black 1pt solid; text-align: right" title="Aggregate intrinsic value, Outstanding ending balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">22,290,069</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Exercisable,
September 30, 2023</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zJW8NDpTVbOa" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of options, Exercisable"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,604,614</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zhq3b5hS8iE" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price, Exercisable"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.19</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z7ZLBQG8DOQ9" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average grant date fair value, Exercisable"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.94</span></td>
<td style="padding-bottom: 2.5pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_iI_pp0p0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zde5865tfxlf" style="border-bottom: Black 2.5pt double; text-align: right" title="Aggregate intrinsic value, Exercisable"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">22,290,069</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



<p id="xdx_8AD_zEuKBqIga3vj" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
following summarizes information about stock options at September 30, 2023 by a range of exercise prices:</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<table cellpadding="0" cellspacing="0" id="xdx_89A_eus-gaap--ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_zEoDtaKA8WQ4" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 4)">
<tr style="vertical-align: bottom">
<td colspan="3" style="font-size: 10pt; text-align: left"><span id="xdx_8B5_zZ1azt0WqCG3" style="display: none">Schedule of summarizes information about stock options</span></td>
<td style="font-size: 10pt">&#160;</td>
<td colspan="3" style="font-size: 10pt; text-align: center">&#160;</td>
<td style="font-size: 10pt">&#160;</td>
<td colspan="3" style="font-size: 10pt; text-align: center">&#160;</td>
<td>&#160;</td>
<td colspan="3" style="text-align: center">&#160;</td>
<td>&#160;</td>
<td colspan="3" style="text-align: center">&#160;</td>
<td style="font-size: 10pt">&#160;</td>
<td colspan="3" style="font-size: 10pt; text-align: center">&#160;</td>
<td style="font-size: 10pt">&#160;</td>
<td colspan="3" style="font-size: 10pt; text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom">
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">average</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom">
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Number of</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">remaining</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">average</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted</span></td></tr>
<tr style="vertical-align: bottom">
<td colspan="7" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Range of exercises
prices</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">outstanding</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">contractual</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">exercise</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Number of</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">average</span></td></tr>
<tr style="vertical-align: bottom">
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">From</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">To</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">options</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">life</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">price</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">vested options</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">exercise price</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zJYXBWgUxKda" style="width: 11%; text-align: right" title="Range of exercise prices, Lower range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">0.92</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_znfdhmj2ADy3" style="width: 11%; text-align: right" title="Range of exercise prices, Upper range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.00</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zik41maNOF0h" style="width: 11%; text-align: right" title="Number of outstanding options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3,280,309</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_903_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zOoekuBKWZEa" title="Weighted average remaining contractual life">4.74</span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zJmshsBbEIab" style="width: 10%; text-align: right" title="Weighted average exercise price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.39</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_987_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zbnUPrIBpwV2" style="width: 10%; text-align: right" title="Number of vested options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3,280,309</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_z9mbrl6XrXf" style="width: 10%; text-align: right" title="Weighted average exercise price options vested"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.39</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_986_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_z7Y8nycQuh9a" style="text-align: right" title="Range of exercise prices, Lower range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.01</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98B_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_z086mh1eEJ4h" style="text-align: right" title="Range of exercise prices, Upper range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.00</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zWp1gnuPFd1h" style="text-align: right" title="Number of outstanding options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,017,500</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90D_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zfpbf6GJ6g7c" title="Weighted average remaining contractual life">4.32</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zCMjYCjifoc" style="text-align: right" title="Weighted average exercise price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.28</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zw5cQQ4bQl4a" style="text-align: right" title="Number of vested options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,017,500</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_ze2Cbpm9tHh3" style="text-align: right" title="Weighted average exercise price options vested"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.28</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zfnYJas5hHn5" style="text-align: right" title="Range of exercise prices, Lower range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.01</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zjw2rHU2tdde" style="text-align: right" title="Range of exercise prices, Upper range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">9.00</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zJwiUtbGVNFa" style="text-align: right" title="Number of outstanding options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5,260,054</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_903_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zv4ZErt5pUja" title="Weighted average remaining contractual life">6.21</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zAumZywNL2Bk" style="text-align: right" title="Weighted average exercise price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.90</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zKxXBt473Zje" style="text-align: right" title="Number of vested options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3,304,137</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zr1Kzn0lL1M5" style="text-align: right" title="Weighted average exercise price options vested"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.10</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zLMY1YARIpUe" style="text-align: right" title="Range of exercise prices, Lower range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">9.01</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_z4hniAZlE363" style="text-align: right" title="Range of exercise prices, Upper range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">13.00</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zJdUNRWEL8Ql" style="text-align: right" title="Number of outstanding options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,981,917</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90D_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zVADhDSFa35f" title="Weighted average remaining contractual life">8.37</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_z7Spxmdt2g87" style="text-align: right" title="Weighted average exercise price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">10.55</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zm06iu99nx94" style="text-align: right" title="Number of vested options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">480,584</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zVXTV9kNNHI3" style="text-align: right" title="Weighted average exercise price options vested"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">11.45</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zMWFZE1Vdnyc" style="text-align: right" title="Range of exercise prices, Lower range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">13.01</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zoLuZjUZdnX4" style="text-align: right" title="Range of exercise prices, Upper range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">25.00</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_z8NHOEOWSvB9" style="border-bottom: Black 1pt solid; text-align: right" title="Number of outstanding options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,572,000</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zLQK7QouAmE9" title="Weighted average remaining contractual life">7.49</span></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zTu44CHbESU8" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">18.29</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_982_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zekHKoPStc37" style="border-bottom: Black 1pt solid; text-align: right" title="Number of vested options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">522,084</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zaAU3Mj6dCX1" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price options vested"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">18.57</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"></td>
<td style="padding-bottom: 2.5pt; font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"></td>
<td style="padding-bottom: 2.5pt; font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zt2AET0WMtzk" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of outstanding options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">14,111,780</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90B_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zrvSy6PHWlcg" title="Weighted average remaining contractual life">6.04</span></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zz5zxf8fZNo8" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7.12</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zQ4zwY5uofia" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of vested options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,604,614</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zvNCPuWNKxpi" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price options vested"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.19</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



<p id="xdx_8A4_zmiwvETXlO4e" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>
















<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
weighted average per share fair value of options vested during the year ended September 30, 2023 was $<span id="xdx_90F_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_pip0_c20221001__20230930_zhxiHcVEOz8" title="Weighted average grant date fair value of options vested">3.94</span> (2022: $<span id="xdx_90F_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_pip0_c20211001__20220930_zQQWTKVXN7j2" title="Weighted average grant date fair value of options vested">4.69</span>, 2021: $<span id="xdx_905_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_pip0_c20201001__20210930_zEZMrPGIxEC1" title="Weighted average grant date fair value of options vested">2.54</span>).
At September 30, 2023, the weighted average contractual life of options outstanding was <span id="xdx_903_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930_zBHZY8takBBa" title="Weighted average contractual life of options outstanding">6.0</span> years (2022: <span id="xdx_905_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20211001__20220930_zTFCW5ySvsgf" title="Weighted average contractual life of options outstanding">6.4</span> years) and for options exercisable
was <span id="xdx_904_eus-gaap--SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930_z7IOtwJb2Aoj" title="Options exercisable">4.75</span> years (2022: <span id="xdx_904_eus-gaap--SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_dtY_c20211001__20220930_zEa7SxOeqOih" title="Options exercisable">5.1</span> years).</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
aggregate intrinsic value is calculated as the difference between the exercise price of the underlying awards and the quoted market price
of the Company&#8217;s stock for the options that were in-the-money at September 30, 2023.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">	The
Company recognized stock-based compensation expense of $<span id="xdx_909_eus-gaap--AllocatedShareBasedCompensationExpense_pn5n6_c20221001__20230930_zH6p6tZw0jW" title="Share based compensation">16.4</span> million during the year ended September 30, 2023 (2022: $<span id="xdx_90A_eus-gaap--AllocatedShareBasedCompensationExpense_pn5n6_c20211001__20220930_zGbryIoD3SS9" title="Share based compensation">18.4</span> million; 2021:
$<span id="xdx_907_eus-gaap--AllocatedShareBasedCompensationExpense_pn5n6_c20201001__20210930_zksFCXqaXAHj" title="Share based compensation">8.2</span> million) in connection with the issuance and vesting 	of stock options in exchange for services. These amounts have been included
in general and 	administrative expenses and research and development expenses on the Company&#8217;s consolidated statements of 	operations
as follows (in thousands):</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p><p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"></p>

<p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"></p>


<table cellpadding="0" cellspacing="0" id="xdx_893_eus-gaap--ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_pn3n3_zi05WuRK54V9" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 5)">
<tr style="vertical-align: bottom">
<td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; text-align: left; text-indent: -10pt"><span id="xdx_8B0_zVkn5OI5YY12" style="display: none">Schedule of general and administrative expenses and research and development expenses</span></td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="11" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30,</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">General
and administrative</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_98A_eus-gaap--ShareBasedCompensation_pn3n3_c20221001__20230930__us-gaap--IncomeStatementLocationAxis__us-gaap--GeneralAndAdministrativeExpenseMember_zlegHFiNw3u9" style="width: 11%; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5,558</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensation_pn3n3_c20211001__20220930__us-gaap--IncomeStatementLocationAxis__us-gaap--GeneralAndAdministrativeExpenseMember_zt8VbpPKl4ri" style="width: 11%; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7,129</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensation_pn3n3_c20201001__20210930__us-gaap--IncomeStatementLocationAxis__us-gaap--GeneralAndAdministrativeExpenseMember_ztXzYhbjPTtj" style="width: 11%; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3,571</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98E_eus-gaap--ShareBasedCompensation_pn3n3_c20221001__20230930__us-gaap--IncomeStatementLocationAxis__us-gaap--ResearchAndDevelopmentExpenseMember_zxlwTaY7roA2" style="border-bottom: Black 1pt solid; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">10,812</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensation_pn3n3_c20211001__20220930__us-gaap--IncomeStatementLocationAxis__us-gaap--ResearchAndDevelopmentExpenseMember_zMnF2RIYqYD7" style="border-bottom: Black 1pt solid; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">11,250</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_987_eus-gaap--ShareBasedCompensation_pn3n3_c20201001__20210930__us-gaap--IncomeStatementLocationAxis__us-gaap--ResearchAndDevelopmentExpenseMember_zbbLNUWHcCQk" style="border-bottom: Black 1pt solid; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">4,660</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total
stock-based compensation</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_983_eus-gaap--ShareBasedCompensation_pn3n3_c20221001__20230930_zBefjtLfXJBl" style="border-bottom: Black 2.5pt double; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">16,370</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensation_pn3n3_c20211001__20220930_zJqVKJNEeNN2" style="border-bottom: Black 2.5pt double; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">18,379</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensation_pn3n3_c20201001__20210930_zNPDO6PYdgbh" style="border-bottom: Black 2.5pt double; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">8,231</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



<p id="xdx_8A1_zEmZAKeGAs8d" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">An
amount of approximately $<span id="xdx_90F_eus-gaap--EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_iI_pn5n6_c20230930_zHwO246Nknc7" title="Remaining stock based compensation">14.1 </span>million in stock-based compensation is expected to be recorded over the remaining term 	of such options
and warrants through fiscal 2026.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
fair value of each option and warrant award is estimated on the date of grant using the Black Scholes option pricing model based on the
following weighted average assumptions:</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<table cellpadding="0" cellspacing="0" id="xdx_89D_ecustom--ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock_zN55WsDXEShe" style="font: 10.5pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 6)">
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span id="xdx_8B4_zaAFre5XkJXj" style="display: none">Schedule of weighted average assumptions for fair value of each option award</span></td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Risk-free
interest rate</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_pip0_dp_c20221001__20230930_zKO6cup4Qeu1" title="Risk-free interest rate">3.70</span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_pip0_dp_c20211001__20220930_zHZHxDG4efy4" title="Risk-free interest rate">3.11</span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_909_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_pip0_dp_c20201001__20210930_zT78UQ0afMp7" title="Risk-free interest rate">0.73</span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Expected
life of options (years)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90F_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_dtY_c20221001__20230930_zQgzQUIlWFjg" title="Expected life of options (years)">5.64</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_908_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_dtY_c20211001__20220930_zMxT0K2f40o5" title="Expected life of options (years)">5.57</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_901_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_dtY_c20201001__20210930_zfLzebHEUPni" title="Expected life of options (years)">5.74</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Annualized
volatility</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_pip0_dp_c20221001__20230930_z5WfFe3kdgzj" title="Annualized volatility">85.13</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_pip0_dp_c20211001__20220930_zAKopGanU2f2" title="Annualized volatility">84.17</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_904_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_pip0_dp_c20201001__20210930_zQ9PnpHPDlV2" title="Annualized volatility">93.43</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Dividend
rate</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_pip0_dp_c20221001__20230930_zQJP91L18KX4" title="Dividend rate">0.00</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_909_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_pip0_dp_c20211001__20220930_z2gilqQmyEg5" title="Dividend rate">0.00</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_pip0_dp_c20201001__20210930_z90iEDkkPtbe" title="Dividend rate">0.00</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td></tr>
</table>



<p id="xdx_8A2_zyMT6BsApCPj" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
fair value of stock compensation charges recognized during the years ended September 30, 2023, 2022 and 2021 was determined with reference
to the quoted market price of the Company&#8217;s shares on the grant date.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>















<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: 10pt Times New Roman, Times, Serif"></span></p>


<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommitmentsAndContingenciesDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommitmentsAndContingenciesDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommitmentsDisclosureTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for significant arrangements with third parties, which includes operating lease arrangements and arrangements in which the entity has agreed to expend funds to procure goods or services, or has agreed to commit resources to supply goods or services, and operating lease arrangements. Descriptions may include identification of the specific goods and services, period of time covered, minimum quantities and amounts, and cancellation rights.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 440<br> -Name Accounting Standards Codification<br> -Publisher FASB<br> -URI https://asc.fasb.org//440/tableOfContent<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommitmentsDisclosureTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>30
<FILENAME>R14.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649477121824">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Income Taxes<br></strong></div></th>
<th class="th" colspan="1">12 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2023</div></th></tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxDisclosureAbstract', window );"><strong>Income Tax Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxDisclosureTextBlock', window );">Income Taxes</a></td>
<td class="text"><p id="xdx_809_eus-gaap--IncomeTaxDisclosureTextBlock_zskvIWwUEx38" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
7	 	<span id="xdx_82F_z9n0dvl8UTs4">Income Taxes</span> </b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company&#8217;s U.S. and foreign loss before income taxes are set forth below (in thousands):</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<table cellpadding="0" cellspacing="0" id="xdx_894_eus-gaap--ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock_pn3n3_z4sCfQjlSamk" style="font: 9.5pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Income Taxes (Details)">
<tr style="vertical-align: bottom">
<td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left"><span id="xdx_8B0_zY6zjeyTPFke" style="display: none">Schedule of loss before
income taxes</span></td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_496_20221001_20230930" style="text-align: center">&#160;</td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_494_20211001_20220930" style="text-align: center">&#160;</td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_492_20201001_20210930" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr id="xdx_408_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">United
States</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(41,198</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(40,002</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(28,851</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_406_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_zSoEJlgOqv97" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Foreign</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(6,300</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(7,618</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(8,790</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_40A_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_z76oU3PPoFLf" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(47,498</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(47,620</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(37,641</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
</table>



<p id="xdx_8A6_znTzPaTwtQal" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
components of net deferred income tax assets as of September 30, 2023, 2022 and 2021 are as follows (in thousands):</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 12pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>

<table cellpadding="0" cellspacing="0" id="xdx_893_eus-gaap--ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_pn3n3_z2nP6y5V9QFk" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Income Taxes (Details 1)">
<tr style="vertical-align: bottom">
<td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left"><span id="xdx_8BF_zF3rKRkptpk8" style="display: none">Schedule of components of
net deferred income tax assets</span></td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_49D_20230930" style="text-align: center">&#160;</td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_493_20220930" style="text-align: center">&#160;</td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_498_20210930_zaE4q2jgcLma" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr id="xdx_40B_eus-gaap--DeferredTaxAssetsOperatingLossCarryforwards_iI_z9TlGYr5v4be" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net
operating loss carryforwards</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">46,462</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">46,208</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">34,982</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_409_eus-gaap--DeferredTaxAssetsInProcessResearchAndDevelopment_iI_zEOjZKyH2Mn2" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development tax credit carryforwards</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,713</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,182</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,577</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_408_eus-gaap--DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_iI_zpUuEvXfHkF2" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Stock-based
compensation</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">18,593</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">13,373</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">10,453</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_407_ecustom--DeferredTaxAssetsResearchAndDevelopmentCapitalization_iI_zXJnEltE20u1" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development capitalization</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7,219</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1029">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1030">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_408_ecustom--DeferredTaxAssetsUnpaidCharges_iI_zX2XoiNZ1rjk" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Unpaid
charges</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,559</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">894</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">89</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40A_eus-gaap--DeferredTaxAssetsGoodwillAndIntangibleAssets_iI_zQyMqOHHjd39" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Intangible
asset costs</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">593</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">388</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">323</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_403_eus-gaap--DeferredTaxAssetsUnrealizedCurrencyLosses_iI_zS92gCVLPkw" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Foreign
exchange and other</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">49</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">44</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">62</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40B_eus-gaap--DeferredTaxAssetsValuationAllowance_iNI_di_z51AqN69x9S5" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Valuation
allowance of deferred tax assets</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(77,188</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(63,089</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(47,486</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_40E_eus-gaap--DeferredTaxAssetsNet_iI_zTZlhwMjO2M1" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net
deferred tax assets</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1048">&#8212;</span></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1049">&#8212;</span></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1050">&#8212;</span></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>


<p id="xdx_8A7_zl9mCbge1VK9" style="font: 12pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">A
reconciliation of income tax expense at the statutory federal income tax rate and income taxes as reflected in the consolidated financial
statements for the years ended September 30, 2023, 2022 and 2021 is as follows (in thousands):</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 12pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"></span></p>

<table cellpadding="0" cellspacing="0" id="xdx_89E_eus-gaap--ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_pn3n3_zsVzljCQ03c6" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Income Taxes (Details 2)">
<tr style="vertical-align: bottom">
<td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><span id="xdx_8BA_z701s73Iniah" style="display: none">Schedule
of reconciliation of income tax expense</span></td>
<td>&#160;</td>
<td colspan="3" id="xdx_49C_20221001__20230930_z6poV6auzo5i" style="text-align: center">&#160;</td>
<td>&#160;</td>
<td colspan="3" id="xdx_495_20211001__20220930_zgRuwYwJDgEf" style="text-align: center">&#160;</td>
<td>&#160;</td>
<td colspan="3" id="xdx_493_20201001__20210930_zLPqPPjEels4" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr id="xdx_40D_eus-gaap--IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_zRekekCgXmOh" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Income
tax benefit at statutory federal rate</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(9,975</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(10,000</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(7,934</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_40C_eus-gaap--IncomeTaxReconciliationForeignIncomeTaxRateDifferential_ziOeNTMw5XHh" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Foreign
income taxed at other rates</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1058">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(170</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(353</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_408_ecustom--PermanentDifferencesRelatingToStockBasedCompensation_zMH8Yb6MSbN9" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Permanent
differences relating to stock based compensation</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(601</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(714</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(4,379</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_40A_eus-gaap--EffectiveIncomeTaxRateReconciliationGiltiAmount_zuYDNTfabwmg" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Permanent
differences relating to GILTI inclusion</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">165</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1067">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1068">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_401_ecustom--PermanentDifferencesRelatingToSection162m_zopWtm3badqj" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Permanent
differences relating to Section 162(m)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1070">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1071">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">816</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40F_eus-gaap--IncomeTaxReconciliationOtherAdjustments_i_pp0p0" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Other
permanent differences</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">273</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1075">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">741</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_401_ecustom--AdjustmentToTaxAssetsBasedOnSection382_zAIrAcBONkAk" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Adjustment
to tax assets based on Section 382</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1078">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1079">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3,330</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_408_ecustom--IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet_zlsUXX2azvUd" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development credits, net</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(37</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">232</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,042</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_405_eus-gaap--IncomeTaxReconciliationStateAndLocalIncomeTaxes_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">State
and local taxes</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(4,122</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(4,975</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(7,022</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_40C_eus-gaap--IncomeTaxReconciliationPriorYearIncomeTaxes_i_pp0p0" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Adjustment
to true up to prior years' tax provision</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">206</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">24</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">48</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40B_eus-gaap--IncomeTaxReconciliationChangeInEnactedTaxRate_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Effect
of change in statutory tax rates</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1094">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1095">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">216</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_408_eus-gaap--TaxesExcludingIncomeAndExciseTaxes_i_pp0p0" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">State
minimum and excise taxes</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1098">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">358</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">268</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40C_eus-gaap--IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Change
in valuation allowances</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">14,098</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">15,603</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">13,495</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_405_eus-gaap--DeferredIncomeTaxExpenseBenefit_i_pp0p0" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Income
tax expense</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">358</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">268</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>


<p id="xdx_8A4_z3qn8d22c1X8" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>
















<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">As
of September 30, 2023, the Company had U.S. federal net operating loss carryforwards of approximately $<span id="xdx_90A_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20230930__us-gaap--IncomeTaxAuthorityAxis__custom--FederalMember_zosExQ9Ni2ve" title="Operating loss carryforwards">126.3</span> million (2022: $<span id="xdx_90A_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20220930__us-gaap--IncomeTaxAuthorityAxis__custom--FederalMember_znacYwgHTTK7" title="Operating loss carryforwards">123.4</span> million)
of which <span id="xdx_905_ecustom--OperatingLossCarryforwardsDescription_c20221001__20230930__us-gaap--IncomeTaxAuthorityAxis__custom--FederalMember_z90eQ9gTvLZ2" title="Operating loss carryforwards description">$37.7 million will begin to expire in 2025 and $88.6 million can be carried forward indefinitely</span>, state and local net operating
loss carryforwards of approximately $ <span id="xdx_90C_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20230930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--StateAndLocalJurisdictionMember_znWgRNUdAPJi" title="Operating loss carryforwards">16.6</span> million (2022: $<span id="xdx_903_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20220930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--StateAndLocalJurisdictionMember_zkKt1osnqZF" title="Operating loss carryforwards">17.2</span> million) which will begin to expire in <span id="xdx_900_ecustom--OperatingLossCarryForwardsExpirationYear_c20221001__20230930_zdJ60uniXWnf" title="Operating loss carry forwards expiration year">2036</span>, and Research and Development
tax credits of approximately $<span id="xdx_90E_eus-gaap--IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment_pn5n6_c20221001__20230930_zQ2xyYUFqcF4" title="Research and Development tax credits">2.7</span> million (2022: $<span id="xdx_90E_eus-gaap--IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment_pn5n6_c20211001__20220930_zwbv1IZxF4yf" title="Research and Development tax credits">2.2</span> million) which will begin to expire in <span id="xdx_901_ecustom--ResearchAndDevelopmentTaxCreditsYear_c20221001__20230930_z37rCamF6FZf" title="Research and development tax credits year">2029</span>. The Company had approximately $<span id="xdx_908_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20230930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--ForeignCountryMember_zqR1kpkjOcZi" title="Operating loss carryforwards">12.9</span>
million (approximately AU$<span id="xdx_90C_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20230930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--ForeignCountryMember__srt--CurrencyAxis__currency--AUD_ztNLboBVPHeh" title="Operating loss carryforwards">20.1</span> million) (2022: $<span id="xdx_909_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20220930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--ForeignCountryMember_ziNKvWRETWKa" title="Operating loss carryforwards">10.6</span> million (approximately AU$ <span id="xdx_90A_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20220930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--ForeignCountryMember__srt--CurrencyAxis__currency--AUD_zPtmb3CPEkbk" title="Operating loss carryforwards">14.9</span> million)) of net operating loss carryforwards in
Australia, which have an indefinite life, available to offset future taxable income in those jurisdictions.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>


<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company evaluates its valuation allowance requirements based on available evidence. When circumstances change, and this causes a change
in management&#8217;s judgment about the recoverability of deferred tax assets, the impact of the change on the valuation allowance is
reflected in current income. Because management of the Company does not currently believe that it is more likely than not that the Company
will receive the benefit of these assets, a valuation allowance has been established at September 30, 2023 and 2022.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Tax Cuts and Jobs Act of 2017 (TCJA) has modified the IRC 174 expenses related to research and development for tax years beginning after
December 31, 2021. Under the TCJA, the Company must now capitalize the expenditures related to research and development activities and
amortize over five years for U.S. activities and 15 years for non-U.S. activities using a mid-year convention. Therefore, the capitalization
of research and development costs in accordance with IRC 174 resulted in a gross deferred tax asset of $<span id="xdx_902_eus-gaap--DeferredTaxAssetsGross_iI_pn5n6_c20230930_z5Huz0MUkYf6" title="Gross deferred tax asset">7.2</span> million.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Uncertain
Tax Positions</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company files income tax returns in the U.S. federal jurisdiction and various state and local and foreign jurisdictions. The Company&#8217;s
tax returns are subject to tax examinations by U.S. federal and state tax authorities, or examinations by foreign tax authorities until
the respective statutes of limitation expire. The Company is subject to tax examinations by tax authorities for all taxation years commencing
on or after 2005.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Under
the provisions of the Internal Revenue Code, the net operating loss (&#8220;NOL&#8221;) carryforwards are subject to review and possible
adjustment by the Internal Revenue Service and state tax authorities. Under Section 382 of the Internal Revenue Code, NOL and tax credit
carryforwards may become subject to an annual limitation in the event of an over 50% cumulative change in the ownership interest of significant
stockholders over a three-year period, as well as similar state tax provisions.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company conducted a Section 382 study during the year ended September 30, 2021 and determined that, during the year ended September 30,
2015, there was a change in ownership which resulted in $<span id="xdx_901_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20150930__us-gaap--IncomeTaxAuthorityAxis__custom--FederalMember_zuBVmpmXLoCf" title="Operating loss carryforwards">25.8</span> million of federal NOLs being subject to an annual limitation. During the
year ended September 30, 2021, the Company reduced its federal NOLs by $<span id="xdx_909_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20210930__us-gaap--IncomeTaxAuthorityAxis__custom--FederalMember_zoCzhr2kvOkb" title="Operating loss carryforwards">12.1</span> million and its Research and Development tax credit carryforwards
by $<span id="xdx_90F_eus-gaap--DeferredTaxAssetsTaxCreditCarryforwardsResearch_iI_pn5n6_c20210930_zkOU6AbJlz5e" title="Research and development tax credit carryforwards">0.8</span> million, which are the amount of tax assets that will expire unutilized pursuant to the Section 382 study. This resulted in a
reduction of $<span id="xdx_90C_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20210930_zkk8l6wnAZm9" title="Operating loss carryforwards">2.5</span> million of NOLs and $<span id="xdx_90F_eus-gaap--DeferredTaxAssetsTaxCreditCarryforwardsResearch_iI_pn5n6_c20210930_zugz7EAgAHc8" title="Research and development tax credit carryforwards">0.8</span> million of research and development credits and a corresponding reduction in the valuation
allowance of $<span id="xdx_901_eus-gaap--ValuationAllowanceDeferredTaxAssetChangeInAmount_pn5n6_c20201001__20210930_zAPCM1FPnLya" title="Decrease in valuation allowance">3.3</span> million, which was recorded in the 2021 fiscal year. Subsequent ownership changes in future years could trigger additional
limitations of the Company&#8217;s NOLs<span style="background-color: white">. During the year ended September 30, 2023 and 2022 the
Company determined that there were no changes in ownership pursuant to Section 382.</span></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">As
of September 30, 2023, the Company did not provide any foreign withholding taxes related to its foreign subsidiaries&#8217; undistributed
earnings, as such earnings have been retained and are intended to be indefinitely reinvested to fund ongoing operations of the foreign
subsidiaries. It is not practicable to estimate the amount of taxes that would be payable upon remittance of these earnings, because
such tax, if any, is dependent upon circumstances existing if and when remittance occur.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxDisclosureTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for income taxes. Disclosures may include net deferred tax liability or asset recognized in an enterprise's statement of financial position, net change during the year in the total valuation allowance, approximate tax effect of each type of temporary difference and carryforward that gives rise to a significant portion of deferred tax liabilities and deferred tax assets, utilization of a tax carryback, and tax uncertainties information.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 13<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480990/946-20-50-13<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(h)(2))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480678/235-10-S99-1<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -Name Accounting Standards Codification<br> -Publisher FASB<br> -URI https://asc.fasb.org//740/tableOfContent<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 14<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-14<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 21<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-21<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 270<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482526/740-270-50-1<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 17<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-17<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB TOPIC 6.I.5.Q1)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479360/740-10-S99-1<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SAB Topic 11.C)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479360/740-10-S99-2<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 30<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482603/740-30-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxDisclosureTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>31
<FILENAME>R15.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649481136848">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Subsequent Events<br></strong></div></th>
<th class="th" colspan="1">12 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2023</div></th></tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SubsequentEventsAbstract', window );"><strong>Subsequent Events [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SubsequentEventsTextBlock', window );">Subsequent Events</a></td>
<td class="text"><p id="xdx_803_eus-gaap--SubsequentEventsTextBlock_z3bCaqjnWyw5" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Note
8	<span id="xdx_827_z2tGny4WyLe6">Subsequent Events</span></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company evaluates subsequent events occurring between the most recent balance sheet date and the date the financial statements are available
to be issued in order to determine whether the subsequent events are to be recorded and/or disclosed in the Company&#8217;s financial
statements and footnotes. The financial statements are considered to be available to be issued at the time they are filed with the Securities
and Exchange Commission (SEC).</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">There
were no subsequent events or transactions that required recognition or disclosure in the consolidated financial statements.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SubsequentEventsAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SubsequentEventsAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SubsequentEventsTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for significant events or transactions that occurred after the balance sheet date through the date the financial statements were issued or the date the financial statements were available to be issued. Examples include: the sale of a capital stock issue, purchase of a business, settlement of litigation, catastrophic loss, significant foreign exchange rate changes, loans to insiders or affiliates, and transactions not in the ordinary course of business.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 855<br> -Name Accounting Standards Codification<br> -Publisher FASB<br> -URI https://asc.fasb.org//855/tableOfContent<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 855<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483399/855-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SubsequentEventsTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>32
<FILENAME>R16.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649475680832">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Summary of Significant Accounting Policies (Policies)<br></strong></div></th>
<th class="th" colspan="1">12 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2023</div></th></tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AccountingPoliciesAbstract', window );"><strong>Accounting Policies [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_UseOfEstimates', window );">Use of Estimates</a></td>
<td class="text"><p id="xdx_848_eus-gaap--UseOfEstimates_z6qiTKflTLI2" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86B_zdIdNWMOYl8g">Use
of Estimates</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
preparation of financial statements in accordance with U.S. GAAP requires management to make estimates and assumptions that affect the
reported amounts of assets and liabilities at the date of the financial statements and the reported amounts of revenue and expenses in
the reporting period. The Company regularly evaluates estimates and assumptions related to accounting for research and development costs,
incentive income receivable, valuation and recoverability of deferred tax assets, stock based compensation, and loss contingencies. The
Company bases its estimates and assumptions on current facts, historical experience, and various other factors that it believes to be
reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and
liabilities and the accrual of costs and expenses that are not readily apparent from other sources. The actual results experienced by
the Company may differ materially and adversely from the Company&#8217;s estimates. To the extent there are material differences between
the estimates and the actual results, future results of operations will be affected.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>







<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>








<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ConsolidationPolicyTextBlock', window );">Principles of Consolidation</a></td>
<td class="text"><p id="xdx_84A_eus-gaap--ConsolidationPolicyTextBlock_z2ffcVZrWlFa" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_867_zBDDP2KxbUlg">Principles
of Consolidation</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">These
consolidated financial statements include the accounts of Anavex Life Sciences Corp. and its wholly-owned subsidiaries, Anavex Australia
Pty Limited (&#8220;Anavex Australia&#8221;), a company incorporated under the laws of Australia, Anavex Germany GmbH, a company incorporated
under the laws of Germany, and Anavex Canada Ltd., a company incorporated under the laws of the Province of Ontario, Canada. All inter-company
transactions and balances have been eliminated.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CashAndCashEquivalentsPolicyTextBlock', window );">Cash and equivalents</a></td>
<td class="text"><p id="xdx_842_eus-gaap--CashAndCashEquivalentsPolicyTextBlock_zD2psO58wgqi" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_860_zXnZYnJ3AxH9">Cash
and equivalents</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company considers only those investments which are highly liquid, readily convertible to cash and that mature within three months from
the date of purchase to be cash equivalents.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">Highly
liquid investments that are considered cash equivalents include money market&#160;accounts, money market&#160;funds&#160;and&#160;certificates
of deposit. The carrying value of cash equivalents approximates fair value due to the short-term maturity of these securities. The Company&#8217;s
investment policy allows for investments in domestic money market certificates, certificates of deposit, money market funds, bonds or
commercial papers, and establishes diversification and credit quality requirements and limits investments by maturity and issuer. The
Company currently maintains its investments at one large well known financial institution.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">The
Company maintains its cash in bank deposit accounts which, at times, may exceed federally insured limits. Accounts are guaranteed by
the Federal Deposit Insurance Corporation (FDIC) up to $<span id="xdx_90E_eus-gaap--CashFDICInsuredAmount_iI_c20230930_zOPrmEbs29Na" title="Federal deposit insurance corporation">250,000</span> under current regulations. At September 30, 2023 and 2022, substantially
all of the Company&#8217;s cash balances were in excess of these federally insured limits. The Company mitigates this risk by maintaining
the majority of its cash balances in a large well-known financial institution. The Company has not experienced any losses in such accounts.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>

<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ResearchAndDevelopmentExpensePolicy', window );">Research and Development Expenses</a></td>
<td class="text"><p id="xdx_849_eus-gaap--ResearchAndDevelopmentExpensePolicy_znu0D1C47Tij" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_869_zOUCigTgWOAl">Research
and Development Expenses</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development costs are expensed as incurred. These expenses are comprised of the costs of the Company&#8217;s proprietary research
and development efforts, including preclinical studies, clinical trials, manufacturing costs, employee salaries and benefits and stock-based
compensation expense, contract services including external research and development expenses incurred under arrangements with third parties
such as contract research organizations (&#8220;CROs&#8221;), facilities costs, overhead costs and other related expenses. Milestone
payments made by the Company to third parties are expensed when the specific milestone has been achieved. Manufacturing costs are expensed
as incurred in accordance with Accounting Standard Codification (&#8220;ASC&#8221;) 730, Research and Development, as these materials
have no alternative future use outside of their intended use.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Nonrefundable
advance payments for goods or services that will be used or rendered for future research and development activities are deferred and
amortized over the period that the goods are delivered, or the related services are performed, subject to an assessment of recoverability.
The Company makes estimates of costs incurred in relation to external CROs, and clinical site costs. When evaluating the adequacy of
the accrued liabilities, the Company analyzes progress of the trials and studies including the phase or completion of events, invoices
received and contracted costs. Judgments and estimates are made in determining the accrued balances at the end of any reporting period.
Actual results could differ from the Company&#8217;s estimates. The Company&#8217;s historical accrual estimates have not been materially
different from actual costs.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>







<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>








<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">In
addition, the Company incurs expenses in respect of intellectual property costs relating to patents and trademarks. The probability of
success and length of time to develop commercial applications of the drugs subject to the underlying patent and trademark costs is difficult
to determine and numerous risks and uncertainties exist with respect to the timely completion of the development projects. There is no
assurance the drugs subject to the underlying patents and trademarks will ever be successfully commercialized.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Due
to these risks and uncertainties, the patent and trademark costs do not meet the definition of an asset and thus are expensed as incurred
within general and administrative expenses.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_RevenueRecognitionIncentives', window );">Research and Development Incentive Income</a></td>
<td class="text"><p id="xdx_84A_eus-gaap--RevenueRecognitionIncentives_zXLfXylE6t0j" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86F_zOf8tSfJTM19">Research
and Development Incentive Income</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company is eligible to obtain certain research and development tax credits, including, through its wholly owned subsidiary Anavex Australia,
the Australian research and development tax incentive credit (the &#8220;Australia R&amp;D credit&#8221;) through a program administered
through the Australian Tax Office (the &#8220;ATO&#8221;) and AusIndustry, a division of the Australian Government&#8217;s Department
of Industry, Innovation and Science (&#8220;AusIndustry&#8221;). The Australia R&amp;D credit program provides for a cash refund based
on a percentage of eligible research and development activities undertaken in Australia by Anavex Australia. Anavex Australia is also
eligible under the Australia R&amp;D credit program to receive the cash refund for certain research and development expenses incurred
by Anavex Australia outside of Australia, to the extent such expenses are pre-approved by AusIndustry pursuant to an advanced overseas
finding application.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Australia R&amp;D credit program is available to eligible companies with an annual aggregate revenue of less than $20.0 million Australian
during the reimbursable period at a rate of 18.5% above the claimant&#8217;s company tax rate in Australia.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
tax incentives are available on the basis of specific criteria with which the Company must comply. Although the tax incentive may be
administered through the local tax authority, the Company has accounted for the incentives outside of the scope of ASC Topic 740, Income
Taxes (&#8220;ASC 740&#8221;), since the incentives are not linked to the Company&#8217;s taxable income and can be realized regardless
of whether the Company has generated taxable income in the respective jurisdictions.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">With
respect to the Australia R&amp;D credit, as there is no authoritative guidance under GAAP for accounting for grants to for-profit business
entities, the Company accounts for the grant by analogy to IAS20 Accounting for Government Grants and Disclosure of Government Assistance
(&#8220;IAS 20&#8221;). The Company recognizes the Research and Development Incentive income as it incurs costs eligible for reimbursement
under the Australia R&amp;D credit program when it is reasonably assured that the cash incentive will be received, as evidenced through
enrollment in the program and when the applicable conditions under the program have been met. The Company accrues for the amount of cash
refund it expects to receive in relation to research and development expenses outside of Australia only to the extent it has received
advanced approval from AusIndustry, pursuant to an approved advanced overseas finding application.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">In
addition, Anavex Australia and Anavex Canada incur Goods and Services Tax (GST) on certain services provided by local vendors. As a domestic
entity in those jurisdictions, Anavex Australia and Anavex Canada are entitled to a refund of the GST paid. Similarly, Anavex Germany
incurs Value Added Tax (VAT) on certain services provided by local vendors, to which it is entitled to a refund of such VAT paid. The
Company&#8217;s estimate of the amount of cash refund it expects to receive related to GST and VAT incurred is included in Incentive
and tax receivables in the accompanying consolidated balance sheets.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_LicenseFeesPolicyTextBlock', window );">License Fees</a></td>
<td class="text"><p id="xdx_843_ecustom--LicenseFeesPolicyTextBlock_zbyGkTcneVC" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_867_zUYRjRzpeyi4">License
Fees</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font: normal 10pt Times New Roman, Times, Serif">The
Company expenses amounts paid to acquire licenses associated with products under development when the ultimate recovery of the amounts
paid is uncertain and the technology has no alternative future use when acquired. Acquisitions of technology licenses are charged to
expense or capitalized based on management&#8217;s assessment regarding the ultimate recoverability of the amounts paid and the potential
for alternative future use. The Company has determined that the technological feasibility for its product candidates is reached when
the requisite regulatory approvals are obtained to make the product available for sale.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font: normal 10pt Times New Roman, Times, Serif">&#160;</span></p>







<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"></p>








<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_EarningsPerSharePolicyTextBlock', window );">Basic and Diluted Loss per Share</a></td>
<td class="text"><p id="xdx_84A_eus-gaap--EarningsPerSharePolicyTextBlock_zCP0CRX2uWKf" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_869_z0KRlrCTQKH4">Basic
and Diluted Loss per Share</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Basic
income/(loss) per common share is computed by dividing net income/(loss) available to common stockholders by the weighted average number
of common shares outstanding during the period. Diluted income/(loss) per common share is computed by dividing net income/(loss) available
to common stockholders by the sum of (1) the weighted-average number of common shares outstanding during the period, (2) the dilutive
effect of the assumed exercise of options and warrants using the treasury stock method and (3) the dilutive effect of other potentially
dilutive securities. For purposes of the diluted net loss per share calculation, options and warrants are potentially dilutive securities
and are excluded from the calculation of diluted net loss per share because their effect would be anti-dilutive.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">As
of September 30, 2023, diluted loss per share excludes <span id="xdx_904_eus-gaap--AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c20221001__20230930_zzmQzTvS2P9b" title="Loss per share for potentially dilutive common shares">14,271,780</span> potentially dilutive common shares (2022 &#8211;<span id="xdx_900_eus-gaap--AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c20211001__20220930_zvFJQdLARASf" title="Loss per share for potentially dilutive common shares">13,329,616</span>; 2021 &#8211;
<span id="xdx_905_eus-gaap--AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c20201001__20210930_zhPkKNvGs2j" title="Loss per share for potentially dilutive common shares">11,540,903</span>) related to outstanding options and warrants, as their effect was anti-dilutive.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_FairValueOfFinancialInstrumentsPolicy', window );">Financial Instruments</a></td>
<td class="text"><p id="xdx_84C_eus-gaap--FairValueOfFinancialInstrumentsPolicy_zsg1xhuLguk9" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_861_z1ynJO0M7YLg">Financial
Instruments</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
book value of the Company&#8217;s financial instruments, consisting of cash and equivalents, incentive and tax receivables, accounts
payable and accrued liabilities approximate their fair value due to the short-term maturity of such instruments. Unless otherwise noted,
it is management&#8217;s opinion that the Company is not exposed to significant interest, currency or credit risks arising from these
financial instruments.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock', window );">Foreign Currency Translation</a></td>
<td class="text"><p id="xdx_845_eus-gaap--ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_zzpRJBWkzLGg" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_863_zFNDDXLlBLU7">Foreign
Currency Translation</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
functional currency of the Company is the US dollar. Monetary items denominated in a foreign currency are translated into US dollars
at exchange rates prevailing at the balance sheet date and non-monetary items are translated at exchange rates prevailing when the assets
were acquired, or obligations incurred. Foreign currency denominated expense items are translated at exchange rates prevailing on the
transaction date. Unrealized gains or losses arising from the translations are credited or charged to income in the period in which they
occur.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company has determined that the functional currency of Anavex Australia Pty Limited, Anavex Germany GmbH, and Anavex Canada Ltd. is also
the US dollar.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SegmentReportingPolicyPolicyTextBlock', window );">Segment and Geographic Reporting</a></td>
<td class="text"><p id="xdx_847_eus-gaap--SegmentReportingPolicyPolicyTextBlock_zmPlKfcJlDNj" style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86A_zRFjDP3i0Wx9">Segment
and Geographic Reporting</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Operating
segments are defined as components of an enterprise for which separate discrete information is available for evaluation by the chief
operating decision maker or decision-making group, in deciding how to allocate resources and in assessing performance. The Company views
its operations and manages its business as one operating segment, which is the business of developing novel therapies for the management
of CNS diseases.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_GrantIncomePolicyTextBlock', window );">Grant Income</a></td>
<td class="text"><p id="xdx_84C_ecustom--GrantIncomePolicyTextBlock_zRVfCktQIAsj" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_865_z4nGz9Qg9Cfe">Grant
Income</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Grant
income is recognized at the fair value of the grant when it is received, and all substantive conditions have been satisfied. Grants received
from government and other agencies in advance of the specific research and development costs to which they relate are deferred and recognized
in the consolidated statements of operations in the period they are earned, typically when the related research and development costs
are incurred.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>







<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>








<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxPolicyTextBlock', window );">Income Taxes</a></td>
<td class="text"><p id="xdx_840_eus-gaap--IncomeTaxPolicyTextBlock_zZy051LYIQye" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86B_zFTWQtNxH2pj">Income
Taxes</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company follows the provisions of ASC 740, which requires the asset and liability method of accounting for income taxes. Under the asset
and liability method, deferred tax assets and liabilities are recognized for the future tax consequences attributable to temporary differences
between the financial statements carrying amounts of existing assets and liabilities and their respective tax bases. Deferred tax assets
and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences
are expected to be recovered or settled.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company follows the provisions of ASC 740 regarding accounting for uncertainty in income taxes. The Company initially recognizes tax
positions in the financial statements when it is more likely than not the position will be sustained upon examination by the tax authorities.
Such tax positions are initially and subsequently measured as the largest amount of tax benefit that is greater than 50% likely of being
realized upon ultimate settlement with the tax authority assuming full knowledge of the position and all relevant facts. Application
requires numerous estimates based on available information. The Company considers many factors when evaluating and estimating its tax
positions and tax benefits, and its recognized tax positions and tax benefits may not accurately anticipate actual outcomes. As additional
information is obtained, there may be a need to periodically adjust the recognized tax positions and tax benefits. These periodic adjustments
may have a material impact on the consolidated statements of operations.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company recognizes interest and penalties related to current income tax expense on the interest income, net line, in the accompanying
consolidated statements of operations. Accrued interest and penalties, if any, are included in accrued liabilities on the consolidated
balance sheets.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationForfeituresPolicyTextBlock', window );">Stock-based Compensation</a></td>
<td class="text"><p id="xdx_841_eus-gaap--ShareBasedCompensationForfeituresPolicyTextBlock_zTxkzG9e8Qce" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86C_zro2ToXrby56">Stock-based
Compensation</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company accounts for all stock-based payments and awards under the fair value method.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
fair value of all share purchase options and warrants are expensed over their contractual vesting period, or over the expected performance
period for only the portion of awards expected to vest, in the case of milestone-based vesting, with a corresponding increase to additional
paid-in capital.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Compensation
costs for stock-based payments with graded vesting are recognized on a straight-line basis. Stock based compensation expense is adjusted
for actual forfeitures of unvested awards as they occur.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company has granted share purchase option awards that vest upon achievement of certain performance criteria, or milestone-based awards.
The Company estimates an implicit service period for achieving performance criteria for each award and recognizes the resulting fair
value as expense over the implicit service period when it concludes that achieving the performance criteria is probable. The Company
periodically reviews and updates as appropriate its estimates of implicit service periods and conclusions on achieving the performance
criteria. Performance awards vest upon achievement of the performance criteria.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
Company uses the Black-Scholes option valuation model to calculate the fair value of share purchase options and warrants at the date
of the grant. This model requires the input of subjective assumptions, including the expected price volatility and expected life of each&#160;award.
The Company uses the U.S. Treasury daily treasury yield curve rates for the expected term of the option as the risk-free rate. The expected
term represents the period that options granted are expected to be outstanding using the simplified method. The Company&#8217;s historical
share option exercise experience does not provide sufficient basis for estimating the expected term. Expected volatility is based on
the average of the daily share price changes over the expected term. The Company does not estimate forfeitures and elects to record actual
forfeitures as they occur. The Company has not paid any dividends on its common stock historically, therefore no assumption of dividend
payments is made in the model. These assumptions consist of estimates of future market conditions, which are inherently uncertain, and
therefore, are subject to management&#8217;s judgment. Changes in these assumptions can materially affect the fair value estimates.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>







<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></p>








<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
purchase price of options or warrants may be paid in cash or, if approved by the Company&#8217;s compensation committee (or in the case
of warrants by the Board of Directors) in advance, &#8220;net settled&#8221; in shares of the Company&#8217;s common stock. In a net
settlement of an option or warrant, the Company does not receive payment of the exercise price from the holder but reduces the number
of shares of common stock issued upon the exercise of the stock option or warrant by the smallest number of whole shares that have an
aggregate fair market value equal to or over the aggregate exercise price for the option shares covered by the option or warrant exercised.
Shares issued pursuant to the exercise of options and warrants are issued from the Company&#8217;s treasury.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_FairValueMeasurementPolicyPolicyTextBlock', window );">Fair Value Measurements</a></td>
<td class="text"><p id="xdx_84F_eus-gaap--FairValueMeasurementPolicyPolicyTextBlock_zJIfEwJU8NVi" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_86F_z75dfpAXfjJj">Fair
Value Measurements</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Fair
value is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal
or most advantageous market for the asset or liability in an orderly transaction between market participants at the measurement date.
Assets and liabilities that are measured at fair value are reported using a three-level fair value hierarchy that prioritizes the inputs
used to measure fair value. This hierarchy maximizes the use of observable inputs and minimizes the use of unobservable inputs. The three
levels of inputs used to measure fair value are as follows:</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Level
1 - 	quoted prices (unadjusted) in active markets for identical assets or liabilities that the Company has the ability to access at
the measurement date;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Level
2 - observable inputs other than Level 1, quoted prices for similar assets or liabilities in active 		markets, quoted prices for
identical or similar assets and liabilities in markets that are not active, and model-derived prices whose inputs are observable or whose
significant value drivers are observable; and</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Level
3 - 	assets and liabilities whose significant value drivers are unobservable by little or no market activity and that are significant
to the fair value of the assets or liabilities.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">At
September 30, 2023 and 2022, the Company did not have any Level 2 or Level 3 assets or liabilities.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock', window );">Recently Adopted Accounting Pronouncements</a></td>
<td class="text"><p id="xdx_84A_eus-gaap--NewAccountingPronouncementsPolicyPolicyTextBlock_zLldraoEwC7c" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i><span id="xdx_864_z3SKDNiOVEng">Recently
Adopted Accounting Pronouncements</span></i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b><i>&#160;</i></b></span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Effective
October 1, 2021, the Company adopted Accounting Standards Update (&#8220;ASU&#8221;) 2019-12, &#8220;Simplifying the Accounting for Income
Taxes (ASC 740)&#8221;, which is intended to simplify various aspects related to accounting for income taxes by removing certain exceptions
to the general principles in Topic 740 and clarifying and amending existing guidance to improve consistent application. There was no
material impact on the Company&#8217;s operations, financial condition, or cash flows.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">On
October 1, 2022, the Company adopted ASU 2021-10, Annual Disclosure Requirements for Business Entities Receiving Government Assistance
(Topic 832) &#8211; Disclosures by Business Entities about Government Assistance, which requires business entities to disclose information
about transactions with a government that are accounted for by applying a grant or contribution model by analogy. For transactions within
scope, the new standard requires the disclosure of information about the nature of the transaction, including significant terms and conditions,
as well as the amounts and specific financial statement line items affected by the transaction. The disclosure of the Company&#8217;s
research and development tax incentive income and receivable is detailed in Note 4.</span></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></p>
















<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_GrantIncomePolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_GrantIncomePolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_LicenseFeesPolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_LicenseFeesPolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AccountingPoliciesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AccountingPoliciesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CashAndCashEquivalentsPolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy for cash and cash equivalents, including the policy for determining which items are treated as cash equivalents. Other information that may be disclosed includes (1) the nature of any restrictions on the entity's use of its cash and cash equivalents, (2) whether the entity's cash and cash equivalents are insured or expose the entity to credit risk, (3) the classification of any negative balance accounts (overdrafts), and (4) the carrying basis of cash equivalents (for example, at cost) and whether the carrying amount of cash equivalents approximates fair value.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482913/230-10-50-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CashAndCashEquivalentsPolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ConsolidationPolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy regarding (1) the principles it follows in consolidating or combining the separate financial statements, including the principles followed in determining the inclusion or exclusion of subsidiaries or other entities in the consolidated or combined financial statements and (2) its treatment of interests (for example, common stock, a partnership interest or other means of exerting influence) in other entities, for example consolidation or use of the equity or cost methods of accounting. The accounting policy may also address the accounting treatment for intercompany accounts and transactions, noncontrolling interest, and the income statement treatment in consolidation for issuances of stock by a subsidiary.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483426/235-10-50-4<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481203/810-10-50-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ConsolidationPolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EarningsPerSharePolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy for computing basic and diluted earnings or loss per share for each class of common stock and participating security. Addresses all significant policy factors, including any antidilutive items that have been excluded from the computation and takes into account stock dividends, splits and reverse splits that occur after the balance sheet date of the latest reporting period but before the issuance of the financial statements.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482662/260-10-50-1<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482662/260-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EarningsPerSharePolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FairValueMeasurementPolicyPolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy for fair value measurements of financial and non-financial assets, liabilities and instruments classified in shareholders' equity. Disclosures include, but are not limited to, how an entity that manages a group of financial assets and liabilities on the basis of its net exposure measures the fair value of those assets and liabilities.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FairValueMeasurementPolicyPolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FairValueOfFinancialInstrumentsPolicy">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy for determining the fair value of financial instruments.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 60<br> -Paragraph 1<br> -SubTopic 10<br> -Topic 820<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482053/820-10-60-1<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -SubTopic 10<br> -Topic 825<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482907/825-10-50-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FairValueOfFinancialInstrumentsPolicy</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy for (1) transactions denominated in a currency other than the reporting enterprise's functional currency, (2) translating foreign currency financial statements that are incorporated into the financial statements of the reporting enterprise by consolidation, combination, or the equity method of accounting, and (3) remeasurement of the financial statements of a foreign reporting enterprise in a hyperinflationary economy.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 830<br> -Name Accounting Standards Codification<br> -Publisher FASB<br> -URI https://asc.fasb.org//830/tableOfContent<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxPolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy for income taxes, which may include its accounting policies for recognizing and measuring deferred tax assets and liabilities and related valuation allowances, recognizing investment tax credits, operating loss carryforwards, tax credit carryforwards, and other carryforwards, methodologies for determining its effective income tax rate and the characterization of interest and penalties in the financial statements.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-03(h)(1))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479886/946-10-S99-3<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 17<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-17<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 9<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-9<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 25<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482525/740-10-45-25<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 28<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482525/740-10-45-28<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 19<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-19<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482765/220-10-50-1<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 20<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-20<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxPolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy pertaining to new accounting pronouncements that may impact the entity's financial reporting. Includes, but is not limited to, quantification of the expected or actual impact.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ResearchAndDevelopmentExpensePolicy">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy for costs it has incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 730<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 05<br> -Paragraph 1<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483044/730-10-05-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ResearchAndDevelopmentExpensePolicy</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_RevenueRecognitionIncentives">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy for sales incentives.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_RevenueRecognitionIncentives</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SegmentReportingPolicyPolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy for segment reporting.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 47<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482785/280-10-55-47<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 29<br> -Subparagraph (d)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-29<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 41<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-41<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 29<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-29<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 29<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-29<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 29<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-29<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 29<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-29<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 29<br> -Subparagraph (e)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-29<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SegmentReportingPolicyPolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationForfeituresPolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy election for determining cost for share-based payment arrangement by either estimating forfeiture expected to occur or by recognizing effect of forfeiture upon occurrence.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 35<br> -Paragraph 1D<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480483/718-10-35-1D<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 35<br> -Paragraph 3<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480483/718-10-35-3<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (m)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationForfeituresPolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_UseOfEstimates">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy for the use of estimates in the preparation of financial statements in conformity with generally accepted accounting principles.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 275<br> -SubTopic 10<br> -Section 50<br> -Paragraph 9<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482861/275-10-50-9<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 275<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482861/275-10-50-4<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (b)<br> -SubTopic 10<br> -Topic 275<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482861/275-10-50-1<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (c)<br> -SubTopic 10<br> -Topic 275<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482861/275-10-50-1<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 11<br> -SubTopic 10<br> -Topic 275<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482861/275-10-50-11<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 12<br> -SubTopic 10<br> -Topic 275<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482861/275-10-50-12<br><br>Reference 7: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 275<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482861/275-10-50-8<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_UseOfEstimates</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>33
<FILENAME>R17.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649481088832">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Accrued Liabilities (Tables)<br></strong></div></th>
<th class="th" colspan="1">12 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2023</div></th></tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_DisclosureAccruedLiabilitiesAbstract', window );"><strong>Accrued Liabilities</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock', window );">Schedule of principal components of accrued liabilities</a></td>
<td class="text"><table cellpadding="0" cellspacing="0" id="xdx_88F_eus-gaap--ScheduleOfAccruedLiabilitiesTableTextBlock_pn3n3_zw7Q0sR5wox1" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Accrued Liabilities (Details)">
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span id="xdx_8B9_z9D2IZIcaaxc" style="display: none">Schedule of principal components of accrued liabilities</span></td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td id="xdx_49F_20230930_zOblcHItXB76" style="text-align: center">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td id="xdx_496_20220930_zC7voMSPrPQc" style="text-align: center">&#160;</td>
<td style="text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="7" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30,</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td></tr>
<tr id="xdx_40F_ecustom--AccruedClinicalSiteAndPatientVisitsCosts_iI_maALCz5rZ_zzgKyxye7SBb" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 56%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accrued
clinical site and patient visits costs</span></td>
<td style="width: 8%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 12%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,006</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 8%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 12%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,031</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_403_eus-gaap--AccruedBonusesCurrent_iI_maALCz5rZ_zPPgeMs8YLF3" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accrued
compensation and benefits</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,360</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,298</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40A_ecustom--FixedContractAccruals_iI_maALCz5rZ_zGGMM1w3vkW4" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Fixed
contract accruals</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">38</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">417</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_405_ecustom--MilestoneBasedContractAccruals_iI_maALCz5rZ_zewnh5C4LrUk" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Milestone
based contract accruals</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,267</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">137</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40B_eus-gaap--OtherAccruedLiabilitiesCurrent_iI_maALCz5rZ_z65jJeLLNDBi" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">All
other accrued liabilities</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,624</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,062</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_400_eus-gaap--AccruedLiabilitiesCurrent_iTI_mtALCz5rZ_zK68g3Y0HK82" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 2.5pt 10pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total
accrued liabilities</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7,295</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5,945</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_DisclosureAccruedLiabilitiesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_DisclosureAccruedLiabilitiesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of the components of accrued liabilities.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>34
<FILENAME>R18.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649475694704">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Commitments and Contingencies (Tables)<br></strong></div></th>
<th class="th" colspan="1">12 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2023</div></th></tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CommitmentsAndContingenciesDisclosureAbstract', window );"><strong>Commitments and Contingencies Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_LeaseCostTableTextBlock', window );">Schedule of operating lease costs</a></td>
<td class="text"><table cellpadding="0" cellspacing="0" id="xdx_892_eus-gaap--LeaseCostTableTextBlock_pn3n3_zebQe0HUsBil" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse" summary="xdx: Disclosure - Commitments and Contingencies (Details)">
  <tr style="vertical-align: bottom">
    <td style="text-align: left"><span id="xdx_8BD_zRdYsDhim6L" style="display: none">Schedule of operating lease costs</span></td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_497_20221001__20230930_zoFz6uIyoz5h" style="text-align: center">&#160;</td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_497_20211001__20220930_zWLZSQljBpKc" style="text-align: center">&#160;</td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_496_20201001__20210930_zMlBeHRgn1ej" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="11" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>September
    30,</b></span></td></tr>
  <tr style="vertical-align: bottom">
    <td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2023</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2022</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2021</b></span></td></tr>
  <tr id="xdx_400_eus-gaap--OperatingLeaseCost_zNr7fwUnSpa" style="vertical-align: bottom; background-color: #CCEEFF">
    <td style="width: 55%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Operating lease costs</span></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">118</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">73</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">131</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  </table>

<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DefinedContributionPlanDisclosuresTableTextBlock', window );">Schedule of contributions under the plan</a></td>
<td class="text"><table cellpadding="0" cellspacing="0" id="xdx_89F_eus-gaap--DefinedContributionPlanDisclosuresTableTextBlock_pn3n3_z6GAoPcUR2E" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse" summary="xdx: Disclosure - Commitments and Contingencies (Details 1)">
  <tr style="vertical-align: bottom">
    <td style="text-align: left"><span id="xdx_8B6_zNZ0ix4JlNLb" style="display: none">Schedule of contributions under the  plan</span></td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_497_20221001__20230930_zA0qushBeCO8" style="text-align: center">&#160;</td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_497_20211001__20220930_zj5JX4iHu8rg" style="text-align: center">&#160;</td>
    <td>&#160;</td>
    <td colspan="3" id="xdx_496_20201001__20210930_zJ6NvaX8QTVe" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
    <td style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td colspan="11" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>September
    30,</b></span></td></tr>
  <tr style="vertical-align: bottom">
    <td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2023</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2022</b></span></td>
    <td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>&#160;</b></span></td>
    <td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>2021</b></span></td></tr>
  <tr id="xdx_40C_eus-gaap--PensionContributions_zAjEbuXkDcDj" style="vertical-align: bottom; background-color: #CCEEFF">
    <td style="width: 55%"><p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Contributions
                           to 401(k) plan</span></p></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">232</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">158</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;$</span></td>
    <td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">129</span></td>
    <td style="width: 1%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
  </table>
<p style="font: 9pt Sans-Serif; margin: 0; color: Red"></p>

<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock', window );">Schedule of share purchase warrants outstanding</a></td>
<td class="text"><table cellpadding="0" cellspacing="0" id="xdx_89E_ecustom--ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock_zKmN5o46PFt7" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 2)">
<tr style="vertical-align: bottom">
<td colspan="3" style="text-align: left"><span id="xdx_8B6_zdQIUyosHM7i" style="display: none">Schedule of share purchase warrants outstanding</span></td>
<td style="text-align: center">&#160;</td>
<td colspan="3" style="text-align: center">&#160;</td>
<td style="text-align: center">&#160;</td>
<td colspan="3" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Number</span></td>
<td style="text-align: center; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Exercise Price</span></td>
<td style="text-align: center; padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Expiry Date</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants1Member_z7DIAed1ljy5" style="width: 26%; text-align: right" title="Number of warrants outstanding"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">150,000</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 8%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants1Member_zSEBrQgKsBAa" style="width: 26%; text-align: right" title="Exercise Price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.17</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 8%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 26%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_906_eus-gaap--WarrantsAndRightsOutstandingMaturityDate_iI_dd_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants1Member_z4XXQCR7NqKd" title="Expiry Date">May 6, 2024</span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants2Member_zek8ir0OxIK2" style="border-bottom: Black 1pt solid; text-align: right" title="Number of warrants outstanding"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">10,000</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants2Member_zckHC5eaRJ0f" style="border-bottom: Black 1pt solid; text-align: right" title="Exercise Price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">12.00</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_903_eus-gaap--WarrantsAndRightsOutstandingMaturityDate_iI_dd_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants2Member_zCjIeYOFUu0j" title="Expiry Date">April 21, 2026</span></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_iI_pip0_c20230930_z1GBMONfXrj9" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of warrants outstanding"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">160,000</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; text-align: right"></td>
<td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 12pt Times New Roman, Times, Serif; padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font: 12pt Times New Roman, Times, Serif; padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; font: 12pt Times New Roman, Times, Serif; text-align: right"></td>
<td style="font: 12pt Times New Roman, Times, Serif; padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ScheduleOfStockOptionsRollForwardTableTextBlock', window );">Schedule of stock option activity</a></td>
<td class="text"><table cellpadding="0" cellspacing="0" id="xdx_890_eus-gaap--ScheduleOfStockOptionsRollForwardTableTextBlock_zahdwjh2ktsa" style="font: 9.5pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 3)">
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span id="xdx_8B4_zBRZ0wob6U9d" style="display: none">Schedule of stock option activity</span></td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted Average</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Average Grant</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Aggregate intrinsic</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Number of</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Exercise Price</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Date Fair Value</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">value</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Options</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">($)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">($)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">($)</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 18%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Outstanding,
September 30, 2021</span></td>
<td style="width: 3%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iS_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zaQEDt8Geqwg" style="width: 16%; text-align: right" title="Number of options, Outstanding beginning balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">11,330,903</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 3%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iS_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zvh9J0z6rNSg" style="width: 16%; text-align: right" title="Weighted average exercise price, Outstanding beginning balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.74</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 3%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_iS_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zm8JuTSr9WZg" style="width: 15%; text-align: right" title="Weighted average grant date fair value, Outstanding beginning balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl0768">&#8212;</span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 3%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_iS_pp0p0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zMVx9451Ez4i" style="width: 15%; text-align: right" title="Aggregate intrinsic value, Outstanding beginning balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">140,132,451</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Granted</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zYDHLx1xNqd" style="text-align: right" title="Number of options, Granted"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,358,000</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_za6WMoclHJt6" style="text-align: right" title="Weighted average exercise price, Granted"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">10.13</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z12ur8IugGNa" style="text-align: right" title="Weighted average grant date fair value, Granted"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7.07</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Forfeited</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_iN_pip0_di_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zzqgqYLwD0x8" style="text-align: right" title="Number of options, Forfeited"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(118,750</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98F_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zz0JNU8yhYOi" style="text-align: right" title="Weighted average exercise price, Forfeited"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.86</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zd5Dfy6k0HWb" style="text-align: right" title="Weighted average grant date fair value, Forfeited"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.23</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Exercised</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--StockIssuedDuringPeriodSharesStockOptionsExercised_iN_pip0_di_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zLVBhCdfo3v2" style="border-bottom: Black 1pt solid; text-align: right" title="Number of options, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(400,537</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zNtv4tKDm84l" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.52</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zyXGXeuunFo" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average grant date fair value, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1.88</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_pp0p0" style="border-bottom: Black 1pt solid; text-align: right" title="Aggregate intrinsic value, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">4,201,015</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Outstanding,
September 30, 2022</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_983_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iS_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zF1F2l3FFbvl" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of options, Outstanding beginning balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">13,169,616</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iS_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zDoB5pRDMJR8" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price, Outstanding beginning balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.61</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_iS_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zP01qsGKaijj" style="border-bottom: Black 2.5pt double; font: normal 10pt Times New Roman, Times, Serif; text-align: right" title="Weighted average grant date fair value, Outstanding beginning balance"><span style="font: normal 10pt Times New Roman, Times, Serif">4.96</span></td>
<td style="padding-bottom: 2.5pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_iS_pp0p0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zoFSMXIeupJ3" style="border-bottom: Black 2.5pt double; text-align: right" title="Aggregate intrinsic value, Outstanding beginning balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">62,267,309</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Granted</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zdGzYZ6nAJ19" style="text-align: right" title="Number of options, Granted"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,959,000</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zZhiagjQKbJd" style="text-align: right" title="Weighted average exercise price, Granted"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">9.30</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_ziClWNBA0fig" style="text-align: right" title="Weighted average grant date fair value, Granted"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.60</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Expired</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Exercised</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_981_eus-gaap--StockIssuedDuringPeriodSharesStockOptionsExercised_iN_pip0_di_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zlKT4O9ITNx2" style="text-align: right" title="Number of options, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(759,753</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zjRxv8zRZ3s6" style="text-align: right" title="Weighted average exercise price, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.34</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_987_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z3bIctfsRpu9" style="text-align: right" title="Weighted average grant date fair value, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">0.95</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_983_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_pp0p0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zumLJJKYvL95" style="text-align: right" title="Aggregate intrinsic value, Exercised"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">4,629,026</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Forfeited</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_iN_pip0_di_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zcgXAyqtdxn7" style="text-align: right" title="Number of options, Forfeited"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(257,083</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z189xmJSdqYh" style="text-align: right" title="Weighted average exercise price, Forfeited"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">12.00</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98E_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zPz67mlunnO8" style="text-align: right" title="Weighted average grant date fair value, Forfeited"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.74</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Cancelled</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#8212;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Outstanding,
September 30, 2023</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iE_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zwxfgYOA6xzc" style="border-bottom: Black 1pt solid; text-align: right" title="Number of options, Outstanding ending balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">14,111,780</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iE_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zDKIrfhkqrwi" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price, Outstanding ending balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7.12</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_iE_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z8QNfw1Q0kMg" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average grant date fair value,  Outstanding ending balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.27</span></td>
<td style="padding-bottom: 1pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_iE_pp0p0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zevpgIbVICHg" style="border-bottom: Black 1pt solid; text-align: right" title="Aggregate intrinsic value, Outstanding ending balance"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">22,290,069</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Exercisable,
September 30, 2023</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zJW8NDpTVbOa" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of options, Exercisable"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,604,614</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zhq3b5hS8iE" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price, Exercisable"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.19</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; color: white"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z7ZLBQG8DOQ9" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average grant date fair value, Exercisable"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.94</span></td>
<td style="padding-bottom: 2.5pt; color: white; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_iI_pp0p0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zde5865tfxlf" style="border-bottom: Black 2.5pt double; text-align: right" title="Aggregate intrinsic value, Exercisable"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">22,290,069</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock', window );">Schedule of summarizes information about stock options</a></td>
<td class="text"><table cellpadding="0" cellspacing="0" id="xdx_89A_eus-gaap--ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_zEoDtaKA8WQ4" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 4)">
<tr style="vertical-align: bottom">
<td colspan="3" style="font-size: 10pt; text-align: left"><span id="xdx_8B5_zZ1azt0WqCG3" style="display: none">Schedule of summarizes information about stock options</span></td>
<td style="font-size: 10pt">&#160;</td>
<td colspan="3" style="font-size: 10pt; text-align: center">&#160;</td>
<td style="font-size: 10pt">&#160;</td>
<td colspan="3" style="font-size: 10pt; text-align: center">&#160;</td>
<td>&#160;</td>
<td colspan="3" style="text-align: center">&#160;</td>
<td>&#160;</td>
<td colspan="3" style="text-align: center">&#160;</td>
<td style="font-size: 10pt">&#160;</td>
<td colspan="3" style="font-size: 10pt; text-align: center">&#160;</td>
<td style="font-size: 10pt">&#160;</td>
<td colspan="3" style="font-size: 10pt; text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom">
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">average</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom">
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Number of</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">remaining</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">average</span></td>
<td style="font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Weighted</span></td></tr>
<tr style="vertical-align: bottom">
<td colspan="7" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Range of exercises
prices</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">outstanding</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">contractual</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">exercise</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Number of</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">average</span></td></tr>
<tr style="vertical-align: bottom">
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">From</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">To</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">options</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">life</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">price</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">vested options</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">exercise price</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zJYXBWgUxKda" style="width: 11%; text-align: right" title="Range of exercise prices, Lower range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">0.92</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_znfdhmj2ADy3" style="width: 11%; text-align: right" title="Range of exercise prices, Upper range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.00</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zik41maNOF0h" style="width: 11%; text-align: right" title="Number of outstanding options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3,280,309</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_903_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zOoekuBKWZEa" title="Weighted average remaining contractual life">4.74</span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zJmshsBbEIab" style="width: 10%; text-align: right" title="Weighted average exercise price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.39</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_987_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zbnUPrIBpwV2" style="width: 10%; text-align: right" title="Number of vested options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3,280,309</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 2%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_z9mbrl6XrXf" style="width: 10%; text-align: right" title="Weighted average exercise price options vested"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.39</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_986_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_z7Y8nycQuh9a" style="text-align: right" title="Range of exercise prices, Lower range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.01</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98B_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_z086mh1eEJ4h" style="text-align: right" title="Range of exercise prices, Upper range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.00</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zWp1gnuPFd1h" style="text-align: right" title="Number of outstanding options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,017,500</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90D_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zfpbf6GJ6g7c" title="Weighted average remaining contractual life">4.32</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zCMjYCjifoc" style="text-align: right" title="Weighted average exercise price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.28</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zw5cQQ4bQl4a" style="text-align: right" title="Number of vested options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,017,500</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_ze2Cbpm9tHh3" style="text-align: right" title="Weighted average exercise price options vested"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.28</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zfnYJas5hHn5" style="text-align: right" title="Range of exercise prices, Lower range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.01</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zjw2rHU2tdde" style="text-align: right" title="Range of exercise prices, Upper range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">9.00</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zJwiUtbGVNFa" style="text-align: right" title="Number of outstanding options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5,260,054</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_903_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zv4ZErt5pUja" title="Weighted average remaining contractual life">6.21</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zAumZywNL2Bk" style="text-align: right" title="Weighted average exercise price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.90</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zKxXBt473Zje" style="text-align: right" title="Number of vested options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3,304,137</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zr1Kzn0lL1M5" style="text-align: right" title="Weighted average exercise price options vested"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.10</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zLMY1YARIpUe" style="text-align: right" title="Range of exercise prices, Lower range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">9.01</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_z4hniAZlE363" style="text-align: right" title="Range of exercise prices, Upper range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">13.00</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zJdUNRWEL8Ql" style="text-align: right" title="Number of outstanding options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,981,917</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90D_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zVADhDSFa35f" title="Weighted average remaining contractual life">8.37</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_z7Spxmdt2g87" style="text-align: right" title="Weighted average exercise price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">10.55</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_980_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zm06iu99nx94" style="text-align: right" title="Number of vested options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">480,584</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zVXTV9kNNHI3" style="text-align: right" title="Weighted average exercise price options vested"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">11.45</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zMWFZE1Vdnyc" style="text-align: right" title="Range of exercise prices, Lower range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">13.01</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zoLuZjUZdnX4" style="text-align: right" title="Range of exercise prices, Upper range limit"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">25.00</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_z8NHOEOWSvB9" style="border-bottom: Black 1pt solid; text-align: right" title="Number of outstanding options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,572,000</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zLQK7QouAmE9" title="Weighted average remaining contractual life">7.49</span></span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zTu44CHbESU8" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">18.29</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_982_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zekHKoPStc37" style="border-bottom: Black 1pt solid; text-align: right" title="Number of vested options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">522,084</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zaAU3Mj6dCX1" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price options vested"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">18.57</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"></td>
<td style="padding-bottom: 2.5pt; font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-size: 10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-size: 10pt; text-align: right"></td>
<td style="padding-bottom: 2.5pt; font-size: 10pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zt2AET0WMtzk" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of outstanding options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">14,111,780</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90B_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zrvSy6PHWlcg" title="Weighted average remaining contractual life">6.04</span></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zz5zxf8fZNo8" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7.12</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_984_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zQ4zwY5uofia" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of vested options"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,604,614</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zvNCPuWNKxpi" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price options vested"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.19</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock', window );">Schedule of general and administrative expenses and research and development expenses</a></td>
<td class="text"><table cellpadding="0" cellspacing="0" id="xdx_893_eus-gaap--ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_pn3n3_zi05WuRK54V9" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 5)">
<tr style="vertical-align: bottom">
<td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; text-align: left; text-indent: -10pt"><span id="xdx_8B0_zVkn5OI5YY12" style="display: none">Schedule of general and administrative expenses and research and development expenses</span></td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="11" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">September
30,</span></td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">General
and administrative</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_98A_eus-gaap--ShareBasedCompensation_pn3n3_c20221001__20230930__us-gaap--IncomeStatementLocationAxis__us-gaap--GeneralAndAdministrativeExpenseMember_zlegHFiNw3u9" style="width: 11%; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">5,558</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensation_pn3n3_c20211001__20220930__us-gaap--IncomeStatementLocationAxis__us-gaap--GeneralAndAdministrativeExpenseMember_zt8VbpPKl4ri" style="width: 11%; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7,129</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_989_eus-gaap--ShareBasedCompensation_pn3n3_c20201001__20210930__us-gaap--IncomeStatementLocationAxis__us-gaap--GeneralAndAdministrativeExpenseMember_ztXzYhbjPTtj" style="width: 11%; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3,571</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_98E_eus-gaap--ShareBasedCompensation_pn3n3_c20221001__20230930__us-gaap--IncomeStatementLocationAxis__us-gaap--ResearchAndDevelopmentExpenseMember_zxlwTaY7roA2" style="border-bottom: Black 1pt solid; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">10,812</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_982_eus-gaap--ShareBasedCompensation_pn3n3_c20211001__20220930__us-gaap--IncomeStatementLocationAxis__us-gaap--ResearchAndDevelopmentExpenseMember_zMnF2RIYqYD7" style="border-bottom: Black 1pt solid; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">11,250</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_987_eus-gaap--ShareBasedCompensation_pn3n3_c20201001__20210930__us-gaap--IncomeStatementLocationAxis__us-gaap--ResearchAndDevelopmentExpenseMember_zbbLNUWHcCQk" style="border-bottom: Black 1pt solid; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">4,660</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total
stock-based compensation</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_983_eus-gaap--ShareBasedCompensation_pn3n3_c20221001__20230930_zBefjtLfXJBl" style="border-bottom: Black 2.5pt double; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">16,370</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td id="xdx_985_eus-gaap--ShareBasedCompensation_pn3n3_c20211001__20220930_zJqVKJNEeNN2" style="border-bottom: Black 2.5pt double; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">18,379</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td id="xdx_988_eus-gaap--ShareBasedCompensation_pn3n3_c20201001__20210930_zNPDO6PYdgbh" style="border-bottom: Black 2.5pt double; text-align: right" title="Total share based compensation"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">8,231</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>



<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock', window );">Schedule of weighted average assumptions for fair value of each option award</a></td>
<td class="text"><table cellpadding="0" cellspacing="0" id="xdx_89D_ecustom--ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock_zN55WsDXEShe" style="font: 10.5pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 6)">
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span id="xdx_8B4_zaAFre5XkJXj" style="display: none">Schedule of weighted average assumptions for fair value of each option award</span></td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td>
<td>&#160;</td>
<td style="text-align: left">&#160;</td>
<td style="text-align: right">&#160;</td>
<td style="text-align: left">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Risk-free
interest rate</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_pip0_dp_c20221001__20230930_zKO6cup4Qeu1" title="Risk-free interest rate">3.70</span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_pip0_dp_c20211001__20220930_zHZHxDG4efy4" title="Risk-free interest rate">3.11</span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_909_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_pip0_dp_c20201001__20210930_zT78UQ0afMp7" title="Risk-free interest rate">0.73</span></span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Expected
life of options (years)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90F_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_dtY_c20221001__20230930_zQgzQUIlWFjg" title="Expected life of options (years)">5.64</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_908_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_dtY_c20211001__20220930_zMxT0K2f40o5" title="Expected life of options (years)">5.57</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_901_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_dtY_c20201001__20210930_zfLzebHEUPni" title="Expected life of options (years)">5.74</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Annualized
volatility</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_pip0_dp_c20221001__20230930_z5WfFe3kdgzj" title="Annualized volatility">85.13</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_pip0_dp_c20211001__20220930_zAKopGanU2f2" title="Annualized volatility">84.17</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_904_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_pip0_dp_c20201001__20210930_zQ9PnpHPDlV2" title="Annualized volatility">93.43</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td></tr>
<tr style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Dividend
rate</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_pip0_dp_c20221001__20230930_zQJP91L18KX4" title="Dividend rate">0.00</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_909_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_pip0_dp_c20211001__20220930_z2gilqQmyEg5" title="Dividend rate">0.00</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span id="xdx_90E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_pip0_dp_c20201001__20210930_z90iEDkkPtbe" title="Dividend rate">0.00</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">%</span></td></tr>
</table>



<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommitmentsAndContingenciesDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommitmentsAndContingenciesDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DefinedContributionPlanDisclosuresTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of defined contribution pension plans or defined contribution other postretirement plans, separately for pension plans and other postretirement benefit plans.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 715<br> -SubTopic 70<br> -Section 50<br> -Paragraph 1<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480794/715-70-50-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DefinedContributionPlanDisclosuresTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LeaseCostTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of lessee's lease cost. Includes, but is not limited to, interest expense for finance lease, amortization of right-of-use asset for finance lease, operating lease cost, short-term lease cost, variable lease cost and sublease income.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 842<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 4<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147478964/842-20-50-4<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LeaseCostTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (h)(1)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (d)<br> -SubTopic 10<br> -Topic 718<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (e)<br> -SubTopic 10<br> -Topic 718<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfStockOptionsRollForwardTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of the change in stock options.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfStockOptionsRollForwardTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>35
<FILENAME>R19.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649474577456">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Income Taxes (Tables)<br></strong></div></th>
<th class="th" colspan="1">12 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2023</div></th></tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxDisclosureAbstract', window );"><strong>Income Tax Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock', window );">Schedule of loss before income taxes</a></td>
<td class="text"><table cellpadding="0" cellspacing="0" id="xdx_894_eus-gaap--ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock_pn3n3_z4sCfQjlSamk" style="font: 9.5pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Income Taxes (Details)">
<tr style="vertical-align: bottom">
<td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left"><span id="xdx_8B0_zY6zjeyTPFke" style="display: none">Schedule of loss before
income taxes</span></td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_496_20221001_20230930" style="text-align: center">&#160;</td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_494_20211001_20220930" style="text-align: center">&#160;</td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_492_20201001_20210930" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr id="xdx_408_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">United
States</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(41,198</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(40,002</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(28,851</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_406_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_zSoEJlgOqv97" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Foreign</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(6,300</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(7,618</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(8,790</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_40A_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_z76oU3PPoFLf" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(47,498</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(47,620</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(37,641</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
</table>



<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock', window );">Schedule of components of net deferred income tax assets</a></td>
<td class="text"><table cellpadding="0" cellspacing="0" id="xdx_893_eus-gaap--ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_pn3n3_z2nP6y5V9QFk" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Income Taxes (Details 1)">
<tr style="vertical-align: bottom">
<td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left"><span id="xdx_8BF_zF3rKRkptpk8" style="display: none">Schedule of components of
net deferred income tax assets</span></td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_49D_20230930" style="text-align: center">&#160;</td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_493_20220930" style="text-align: center">&#160;</td>
<td style="text-align: center">&#160;</td>
<td colspan="3" id="xdx_498_20210930_zaE4q2jgcLma" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="padding-bottom: 1pt; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr id="xdx_40B_eus-gaap--DeferredTaxAssetsOperatingLossCarryforwards_iI_z9TlGYr5v4be" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net
operating loss carryforwards</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">46,462</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">46,208</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">34,982</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_409_eus-gaap--DeferredTaxAssetsInProcessResearchAndDevelopment_iI_zEOjZKyH2Mn2" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development tax credit carryforwards</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,713</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,182</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,577</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_408_eus-gaap--DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_iI_zpUuEvXfHkF2" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Stock-based
compensation</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">18,593</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">13,373</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">10,453</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_407_ecustom--DeferredTaxAssetsResearchAndDevelopmentCapitalization_iI_zXJnEltE20u1" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development capitalization</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7,219</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1029">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1030">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_408_ecustom--DeferredTaxAssetsUnpaidCharges_iI_zX2XoiNZ1rjk" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Unpaid
charges</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,559</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">894</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">89</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40A_eus-gaap--DeferredTaxAssetsGoodwillAndIntangibleAssets_iI_zQyMqOHHjd39" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Intangible
asset costs</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">593</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">388</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">323</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_403_eus-gaap--DeferredTaxAssetsUnrealizedCurrencyLosses_iI_zS92gCVLPkw" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Foreign
exchange and other</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">49</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">44</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">62</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40B_eus-gaap--DeferredTaxAssetsValuationAllowance_iNI_di_z51AqN69x9S5" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Valuation
allowance of deferred tax assets</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(77,188</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(63,089</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(47,486</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_40E_eus-gaap--DeferredTaxAssetsNet_iI_zTZlhwMjO2M1" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net
deferred tax assets</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1048">&#8212;</span></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1049">&#8212;</span></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1050">&#8212;</span></span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>


<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock', window );">Schedule of reconciliation of income tax expense</a></td>
<td class="text"><table cellpadding="0" cellspacing="0" id="xdx_89E_eus-gaap--ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_pn3n3_zsVzljCQ03c6" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Income Taxes (Details 2)">
<tr style="vertical-align: bottom">
<td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"><span id="xdx_8BA_z701s73Iniah" style="display: none">Schedule
of reconciliation of income tax expense</span></td>
<td>&#160;</td>
<td colspan="3" id="xdx_49C_20221001__20230930_z6poV6auzo5i" style="text-align: center">&#160;</td>
<td>&#160;</td>
<td colspan="3" id="xdx_495_20211001__20220930_zgRuwYwJDgEf" style="text-align: center">&#160;</td>
<td>&#160;</td>
<td colspan="3" id="xdx_493_20201001__20210930_zLPqPPjEels4" style="text-align: center">&#160;</td></tr>
<tr style="vertical-align: bottom">
<td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2023</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2022</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">2021</span></td></tr>
<tr id="xdx_40D_eus-gaap--IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_zRekekCgXmOh" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Income
tax benefit at statutory federal rate</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(9,975</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(10,000</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td style="width: 5%"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="width: 11%; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(7,934</span></td>
<td style="width: 1%; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_40C_eus-gaap--IncomeTaxReconciliationForeignIncomeTaxRateDifferential_ziOeNTMw5XHh" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Foreign
income taxed at other rates</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1058">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(170</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(353</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_408_ecustom--PermanentDifferencesRelatingToStockBasedCompensation_zMH8Yb6MSbN9" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Permanent
differences relating to stock based compensation</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(601</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(714</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(4,379</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_40A_eus-gaap--EffectiveIncomeTaxRateReconciliationGiltiAmount_zuYDNTfabwmg" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Permanent
differences relating to GILTI inclusion</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">165</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1067">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1068">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_401_ecustom--PermanentDifferencesRelatingToSection162m_zopWtm3badqj" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Permanent
differences relating to Section 162(m)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1070">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1071">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">816</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40F_eus-gaap--IncomeTaxReconciliationOtherAdjustments_i_pp0p0" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Other
permanent differences</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">273</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1075">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">741</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_401_ecustom--AdjustmentToTaxAssetsBasedOnSection382_zAIrAcBONkAk" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Adjustment
to tax assets based on Section 382</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1078">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1079">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">3,330</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_408_ecustom--IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet_zlsUXX2azvUd" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Research
and development credits, net</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(37</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">232</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">1,042</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_405_eus-gaap--IncomeTaxReconciliationStateAndLocalIncomeTaxes_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">State
and local taxes</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(4,122</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(4,975</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(7,022</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">)</span></td></tr>
<tr id="xdx_40C_eus-gaap--IncomeTaxReconciliationPriorYearIncomeTaxes_i_pp0p0" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Adjustment
to true up to prior years' tax provision</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">206</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">24</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">48</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40B_eus-gaap--IncomeTaxReconciliationChangeInEnactedTaxRate_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Effect
of change in statutory tax rates</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1094">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1095">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">216</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_408_eus-gaap--TaxesExcludingIncomeAndExciseTaxes_i_pp0p0" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">State
minimum and excise taxes</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><span style="-sec-ix-hidden: xdx2ixbrl1098">&#8212;</span></span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">358</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">268</span></td>
<td style="text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_40C_eus-gaap--IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)">
<td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Change
in valuation allowances</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">14,098</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">15,603</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 1pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 1pt solid; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">13,495</span></td>
<td style="padding-bottom: 1pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
<tr id="xdx_405_eus-gaap--DeferredIncomeTaxExpenseBenefit_i_pp0p0" style="vertical-align: bottom; background-color: White">
<td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Income
tax expense</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">7</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">358</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="padding-bottom: 2.5pt"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</span></td>
<td style="border-bottom: Black 2.5pt double; text-align: right"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">268</span></td>
<td style="padding-bottom: 2.5pt; text-align: left"><span style="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</span></td></tr>
</table>


<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Paragraph 2<br> -Section 50<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Paragraph 12<br> -Section 50<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-12<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of income before income tax between domestic and foreign jurisdictions.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(h)(1)(Note 1))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480678/235-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>36
<FILENAME>R20.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649477392800">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Summary of Significant Accounting Policies (Details Narrative) - USD ($)<br></strong></div></th>
<th class="th" colspan="3">12 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AccountingPoliciesAbstract', window );"><strong>Accounting Policies [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CashFDICInsuredAmount', window );">Federal deposit insurance corporation</a></td>
<td class="nump">$ 250,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount', window );">Loss per share for potentially dilutive common shares</a></td>
<td class="nump">14,271,780<span></span>
</td>
<td class="nump">13,329,616<span></span>
</td>
<td class="nump">11,540,903<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AccountingPoliciesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AccountingPoliciesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 260<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482662/260-10-50-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CashFDICInsuredAmount">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The amount of cash deposited in financial institutions as of the balance sheet date that is insured by the Federal Deposit Insurance Corporation.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CashFDICInsuredAmount</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>37
<FILENAME>R21.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649478614048">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Accrued Liabilities (Details) - USD ($)<br> $ in Thousands</strong></div></th>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_DisclosureAccruedLiabilitiesAbstract', window );"><strong>Accrued Liabilities</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_AccruedClinicalSiteAndPatientVisitsCosts', window );">Accrued clinical site and patient visits costs</a></td>
<td class="nump">$ 2,006<span></span>
</td>
<td class="nump">$ 2,031<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AccruedBonusesCurrent', window );">Accrued compensation and benefits</a></td>
<td class="nump">1,360<span></span>
</td>
<td class="nump">1,298<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_FixedContractAccruals', window );">Fixed contract accruals</a></td>
<td class="nump">38<span></span>
</td>
<td class="nump">417<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_MilestoneBasedContractAccruals', window );">Milestone based contract accruals</a></td>
<td class="nump">1,267<span></span>
</td>
<td class="nump">137<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OtherAccruedLiabilitiesCurrent', window );">All other accrued liabilities</a></td>
<td class="nump">2,624<span></span>
</td>
<td class="nump">2,062<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AccruedLiabilitiesCurrent', window );">Total accrued liabilities</a></td>
<td class="nump">$ 7,295<span></span>
</td>
<td class="nump">$ 5,945<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_AccruedClinicalSiteAndPatientVisitsCosts">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_AccruedClinicalSiteAndPatientVisitsCosts</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_DisclosureAccruedLiabilitiesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_DisclosureAccruedLiabilitiesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_FixedContractAccruals">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_FixedContractAccruals</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_MilestoneBasedContractAccruals">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_MilestoneBasedContractAccruals</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AccruedBonusesCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Carrying value as of the balance sheet date of obligations incurred and payable for incentive compensation awarded to employees and directors or earned by them based on the terms of one or more relevant arrangements. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.20)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AccruedBonusesCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AccruedLiabilitiesCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.20)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AccruedLiabilitiesCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherAccruedLiabilitiesCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of expenses incurred but not yet paid classified as other, due within one year or the normal operating cycle, if longer.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.20)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherAccruedLiabilitiesCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>38
<FILENAME>R22.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649474294576">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Other Income (Details Narrative) - USD ($)<br></strong></div></th>
<th class="th" colspan="3">12 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DefinedBenefitPlanDisclosureLineItems', window );"><strong>Defined Benefit Plan Disclosure [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_GrantIncome', window );">Grant income</a></td>
<td class="nump">$ 500,000<span></span>
</td>
<td class="nump">$ 0<span></span>
</td>
<td class="nump">$ 500,000<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned', window );">Research and development incentive income</a></td>
<td class="nump">2,700,000<span></span>
</td>
<td class="nump">3,300,000<span></span>
</td>
<td class="nump">4,500,000<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_NonOperatingIncomeFromGrant', window );">Non operating income from grant</a></td>
<td class="nump">25,000<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="nump">54,100<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_DeferredGrantIncome1', window );">Deferred grant income</a></td>
<td class="nump">900,000<span></span>
</td>
<td class="nump">400,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OtherReceivables', window );">Incentive and tax receivables</a></td>
<td class="nump">2,500,000<span></span>
</td>
<td class="nump">2,900,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_srt_CurrencyAxis=currency_AUD', window );">Australia, Dollars</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DefinedBenefitPlanDisclosureLineItems', window );"><strong>Defined Benefit Plan Disclosure [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned', window );">Research and development incentive income</a></td>
<td class="nump">4,100,000<span></span>
</td>
<td class="nump">4,500,000<span></span>
</td>
<td class="nump">6,100,000<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OtherReceivables', window );">Incentive and tax receivables</a></td>
<td class="nump">$ 3,900,000<span></span>
</td>
<td class="nump">$ 4,500,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis=avxl_MichaelJFoxFoundationMember', window );">Michael J Fox Foundation [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DefinedBenefitPlanDisclosureLineItems', window );"><strong>Defined Benefit Plan Disclosure [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned', window );">Research and development incentive income</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 1,000,000<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_DeferredGrantIncome1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_DeferredGrantIncome1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_GrantIncome">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_GrantIncome</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_NonOperatingIncomeFromGrant">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_NonOperatingIncomeFromGrant</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DefinedBenefitPlanDisclosureLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DefinedBenefitPlanDisclosureLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherReceivables">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount due from parties in nontrade transactions, classified as other.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 210<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.6-04(5)(a)(5))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479617/946-210-S99-1<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(3)(a)(4))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherReceivables</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The amount of compensation earned (contract income) under a research and development arrangement accounted for as a contract to perform research and development for others.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 730<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483041/730-20-50-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_CurrencyAxis=currency_AUD">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_CurrencyAxis=currency_AUD</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis=avxl_MichaelJFoxFoundationMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_RelatedPartyTransactionsByRelatedPartyAxis=avxl_MichaelJFoxFoundationMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>39
<FILENAME>R23.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649474555808">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Equity Offerings (Details Narrative) - USD ($)<br></strong></div></th>
<th class="th" colspan="1"></th>
<th class="th" colspan="1"></th>
<th class="th" colspan="3">12 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Feb. 03, 2023</div></th>
<th class="th"><div>Jun. 22, 2021</div></th>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SalesOfAgreementAmount', window );">Sales of agreement amount</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 142,400,000<span></span>
</td>
<td class="nump">$ 142,400,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_FairValueOfInitialCommitment', window );">Fair value of the initial commitment</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">800,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_IncurredExpenses', window );">Incurred expenses</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 100,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_TypeOfArrangementAxis=avxl_SecuritiesPurchaseAgreementMember', window );">Securities Purchase Agreement [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction', window );">Number of common stock sold</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">2,380,953<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SaleOfStockPricePerShare', window );">Sale of stock, per share</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 21<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SaleOfStockConsiderationReceivedOnTransaction', window );">Gross proceeds from sale of stock</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 50,000,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ProceedsFromIssuanceInitialPublicOffering', window );">Net proceed</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 46,902,981<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_TypeOfArrangementAxis=avxl_EquityOfferingSalesAgreementMember', window );">Equity Offering Sales Agreement [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction', window );">Number of common stock sold</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="nump">1,623,813<span></span>
</td>
<td class="nump">5,634,576<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ProceedsFromIssuanceInitialPublicOffering', window );">Net proceed</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 20,300,000<span></span>
</td>
<td class="nump">$ 76,700,000<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_PercentageOfGrossProceedsFromSales', window );">Percentage of gross proceeds from sales</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">3.00%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SaleOfStockConsiderationReceivedPerTransaction', window );">Number of common stock sold, value</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">21,000,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_SoldForGrossProceedsAmount', window );">Sold for gross proceeds amount</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 79,100,000<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_TypeOfArrangementAxis=avxl_PurchaseAgreement2023Member', window );">Purchase Agreement 2023 [Member] | Lincoln Park Capital Fund L L C [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_ValueOfSharesObligatedToPurchase', window );">Value of shares obligated to purchase</a></td>
<td class="nump">$ 150,000,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodSharesNewIssues', window );">Number of shares issued, shares</a></td>
<td class="nump">75,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_NumberOfSharesObligatedToPurchaseProrataBasic', window );">Pro rata basic number of shares obligated to purchase</a></td>
<td class="nump">75,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ProceedsFromIssuanceOrSaleOfEquity', window );">Proceeds from issuance or sale of equity</a></td>
<td class="nump">$ 150,000,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodValueNewIssues', window );">Number of shares issued, value</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 27,900,000<span></span>
</td>
<td class="nump">$ 0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodValueOther', window );">Amount of shares remain available</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 122,100,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_TypeOfArrangementAxis=avxl_PurchaseAgreement2023Member', window );">Purchase Agreement 2023 [Member] | Lincoln Park Capital Fund L L C [Member] | Common Stock Including Commitment Shares [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodSharesNewIssues', window );">Number of shares issued, shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">3,288,943<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_TypeOfArrangementAxis=avxl_PurchaseAgreement2023Member', window );">Purchase Agreement 2023 [Member] | Lincoln Park Capital Fund L L C [Member] | Common Stock Excluding Commitment Shares [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodSharesNewIssues', window );">Number of shares issued, shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">3,275,000<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_TypeOfArrangementAxis=avxl_PurchaseAgreement2023Member', window );">Purchase Agreement 2023 [Member] | Lincoln Park Capital Fund L L C [Member] | Commitment Shares [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodSharesNewIssues', window );">Number of shares issued, shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">13,943<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_TypeOfArrangementAxis=avxl_PurchaseAgreement2019Member', window );">Purchase Agreement 2019 [Member] | Lincoln Park Capital Fund L L C [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_ValueOfSharesObligatedToPurchase', window );">Value of shares obligated to purchase</a></td>
<td class="nump">$ 50,000,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodSharesNewIssues', window );">Number of shares issued, shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_TypeOfArrangementAxis=avxl_PurchaseAgreement2019Member', window );">Purchase Agreement 2019 [Member] | Lincoln Park Capital Fund L L C [Member] | Common Stock Including Commitment Shares [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodSharesNewIssues', window );">Number of shares issued, shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">4,086,209<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_TypeOfArrangementAxis=avxl_PurchaseAgreement2019Member', window );">Purchase Agreement 2019 [Member] | Lincoln Park Capital Fund L L C [Member] | Common Stock Excluding Commitment Shares [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodSharesNewIssues', window );">Number of shares issued, shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">4,007,996<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_TypeOfArrangementAxis=avxl_PurchaseAgreement2019Member', window );">Purchase Agreement 2019 [Member] | Lincoln Park Capital Fund L L C [Member] | Commitment Shares [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodSharesNewIssues', window );">Number of shares issued, shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">78,213<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_TypeOfArrangementAxis=avxl_PurchaseAgreement2019Member', window );">Purchase Agreement 2019 [Member] | Lincoln Park Capital Fund L L C [Member] | Common Stock [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodValueNewIssues', window );">Number of shares issued, value</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 24,100,000<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_FairValueOfInitialCommitment">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_FairValueOfInitialCommitment</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_IncurredExpenses">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_IncurredExpenses</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_NumberOfSharesObligatedToPurchaseProrataBasic">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_NumberOfSharesObligatedToPurchaseProrataBasic</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_PercentageOfGrossProceedsFromSales">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_PercentageOfGrossProceedsFromSales</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:percentItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_SalesOfAgreementAmount">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_SalesOfAgreementAmount</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_SoldForGrossProceedsAmount">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_SoldForGrossProceedsAmount</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_ValueOfSharesObligatedToPurchase">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_ValueOfSharesObligatedToPurchase</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ProceedsFromIssuanceInitialPublicOffering">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The cash inflow associated with the amount received from entity's first offering of stock to the public.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 14<br> -Subparagraph (a)<br> -SubTopic 10<br> -Topic 230<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-14<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ProceedsFromIssuanceInitialPublicOffering</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ProceedsFromIssuanceOrSaleOfEquity">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The cash inflow from the issuance of common stock, preferred stock, treasury stock, stock options, and other types of equity.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 14<br> -Subparagraph (a)<br> -SubTopic 10<br> -Topic 230<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-14<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-03(i)(1))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479886/946-10-S99-3<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ProceedsFromIssuanceOrSaleOfEquity</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SaleOfStockConsiderationReceivedOnTransaction">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Cash received on stock transaction after deduction of issuance costs.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SaleOfStockConsiderationReceivedOnTransaction</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SaleOfStockConsiderationReceivedPerTransaction">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of consideration received by subsidiary or equity investee in exchange for shares of stock issued or sold. Includes amount of cash received, fair value of noncash assets received, and fair value of liabilities assumed by the investor.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SaleOfStockConsiderationReceivedPerTransaction</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The number of shares issued or sold by the subsidiary or equity method investee per stock transaction.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SaleOfStockPricePerShare">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Per share amount received by subsidiary or equity investee for each share of common stock issued or sold in the stock transaction.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SaleOfStockPricePerShare</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockIssuedDuringPeriodSharesNewIssues">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Number of new stock issued during the period.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -SubTopic 10<br> -Topic 505<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481112/505-10-50-2<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 505<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481004/946-505-50-2<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-09(4)(b))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-3<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-03(i)(1))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479886/946-10-S99-3<br><br>Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(28))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 505<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480008/505-10-S99-1<br><br>Reference 7: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockIssuedDuringPeriodSharesNewIssues</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockIssuedDuringPeriodValueNewIssues">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Equity impact of the value of new stock issued during the period. Includes shares issued in an initial public offering or a secondary public offering.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -SubTopic 10<br> -Topic 505<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481112/505-10-50-2<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 946<br> -SubTopic 830<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 11<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480167/946-830-55-11<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 205<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 4<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480767/946-205-45-4<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 505<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481004/946-505-50-2<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 946<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.6-09(4)(b))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-3<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(28))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br><br>Reference 7: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 505<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480008/505-10-S99-1<br><br>Reference 8: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockIssuedDuringPeriodValueNewIssues</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockIssuedDuringPeriodValueOther">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Value of shares of stock issued attributable to transactions classified as other.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockIssuedDuringPeriodValueOther</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_TypeOfArrangementAxis=avxl_SecuritiesPurchaseAgreementMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_TypeOfArrangementAxis=avxl_SecuritiesPurchaseAgreementMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_TypeOfArrangementAxis=avxl_EquityOfferingSalesAgreementMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_TypeOfArrangementAxis=avxl_EquityOfferingSalesAgreementMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_TypeOfArrangementAxis=avxl_PurchaseAgreement2023Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_TypeOfArrangementAxis=avxl_PurchaseAgreement2023Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_LegalEntityAxis=avxl_LincolnParkCapitalFundLLCMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_LegalEntityAxis=avxl_LincolnParkCapitalFundLLCMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementClassOfStockAxis=avxl_CommonStockIncludingCommitmentSharesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementClassOfStockAxis=avxl_CommonStockIncludingCommitmentSharesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementClassOfStockAxis=avxl_CommonStockExcludingCommitmentSharesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementClassOfStockAxis=avxl_CommonStockExcludingCommitmentSharesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementClassOfStockAxis=avxl_CommitmentSharesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementClassOfStockAxis=avxl_CommitmentSharesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_TypeOfArrangementAxis=avxl_PurchaseAgreement2019Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_TypeOfArrangementAxis=avxl_PurchaseAgreement2019Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementClassOfStockAxis=us-gaap_CommonStockMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementClassOfStockAxis=us-gaap_CommonStockMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>40
<FILENAME>R24.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649474577456">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Commitments and Contingencies (Details) - USD ($)<br> $ in Thousands</strong></div></th>
<th class="th" colspan="3">12 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CommitmentsAndContingenciesDisclosureAbstract', window );"><strong>Commitments and Contingencies Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OperatingLeaseCost', window );">Operating lease costs</a></td>
<td class="nump">$ 118<span></span>
</td>
<td class="nump">$ 73<span></span>
</td>
<td class="nump">$ 131<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommitmentsAndContingenciesDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommitmentsAndContingenciesDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OperatingLeaseCost">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of single lease cost, calculated by allocation of remaining cost of lease over remaining lease term. Includes, but is not limited to, single lease cost, after impairment of right-of-use asset, calculated by amortization of remaining right-of-use asset and accretion of lease liability.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 842<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 53<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479589/842-20-55-53<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 842<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147478964/842-20-50-4<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OperatingLeaseCost</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>41
<FILENAME>R25.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649474895024">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Commitments and Contingencies (Details 1) - USD ($)<br> $ in Thousands</strong></div></th>
<th class="th" colspan="3">12 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CommitmentsAndContingenciesDisclosureAbstract', window );"><strong>Commitments and Contingencies Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_PensionContributions', window );">Contributions to 401(k) plan</a></td>
<td class="nump">$ 232<span></span>
</td>
<td class="nump">$ 158<span></span>
</td>
<td class="nump">$ 129<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommitmentsAndContingenciesDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommitmentsAndContingenciesDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PensionContributions">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of cash outflow for pension benefit. Includes, but is not limited to, employer contribution to fund plan asset and payment to retiree. Excludes other postretirement benefit.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 25<br> -Subparagraph (g)<br> -SubTopic 10<br> -Topic 230<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-25<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PensionContributions</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>42
<FILENAME>R26.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649477610240">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Commitments and Contingencies (Details 2)<br></strong></div></th>
<th class="th">
<div>Sep. 30, 2023 </div>
<div>$ / shares </div>
<div>shares</div>
</th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems', window );"><strong>Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber', window );">Number of warrants outstanding</a></td>
<td class="nump">160,000<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AwardTypeAxis=avxl_PurchaseWarrants1Member', window );">Purchase Warrants 1 [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems', window );"><strong>Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber', window );">Number of warrants outstanding</a></td>
<td class="nump">150,000<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice', window );">Exercise Price | $ / shares</a></td>
<td class="nump">$ 3.17<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_WarrantsAndRightsOutstandingMaturityDate', window );">Expiry Date</a></td>
<td class="text">May  06,  2024<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AwardTypeAxis=avxl_PurchaseWarrants2Member', window );">Purchase Warrants 2 [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems', window );"><strong>Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber', window );">Number of warrants outstanding</a></td>
<td class="nump">10,000<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice', window );">Exercise Price | $ / shares</a></td>
<td class="nump">$ 12.00<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_WarrantsAndRightsOutstandingMaturityDate', window );">Expiry Date</a></td>
<td class="text">Apr. 21,  2026<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 35<br> -Paragraph 1D<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480483/718-10-35-1D<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 35<br> -Paragraph 3<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480483/718-10-35-3<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)(1)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)(2)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)(3)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(i)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(ii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)(01)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)(02)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)(03)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)(04)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(2)(i)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(2)(ii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(2)(iii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 17: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(2)(iii)(01)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(2)(iii)(02)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 19: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(2)(iii)(03)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 20: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (d)(1)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 21: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (d)(2)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 22: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (e)(1)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 23: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (e)(2)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 24: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (f)(2)(i)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 25: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (f)(2)(ii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 26: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (f)(2)(iii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 27: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (f)(2)(iv)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 28: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (f)(2)(v)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Number of fully vested and expected to vest options outstanding that can be converted into shares under option plan. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (e)(1)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Weighted-average exercise price, at which grantee can acquire shares reserved for issuance, for fully vested and expected to vest options outstanding. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (e)(1)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_WarrantsAndRightsOutstandingMaturityDate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Expiration date of outstanding warrant and right embodying unconditional obligation requiring redemption by transferring asset at specified or determinable date or upon event certain to occur, in YYYY-MM-DD format.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 820<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (bbb)(2)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482106/820-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_WarrantsAndRightsOutstandingMaturityDate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:dateItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AwardTypeAxis=avxl_PurchaseWarrants1Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AwardTypeAxis=avxl_PurchaseWarrants1Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AwardTypeAxis=avxl_PurchaseWarrants2Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AwardTypeAxis=avxl_PurchaseWarrants2Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>43
<FILENAME>R27.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649474509216">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Commitments and Contingencies (Details 3) - Equity Option [Member] - USD ($)<br></strong></div></th>
<th class="th" colspan="2">12 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OffsettingAssetsLineItems', window );"><strong>Offsetting Assets [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber', window );">Number of options, Outstanding beginning balance</a></td>
<td class="nump">13,169,616<span></span>
</td>
<td class="nump">11,330,903<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice', window );">Weighted average exercise price, Outstanding beginning balance</a></td>
<td class="nump">$ 6.61<span></span>
</td>
<td class="nump">$ 5.74<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue', window );">Weighted average grant date fair value, Outstanding beginning balance</a></td>
<td class="nump">$ 4.96<span></span>
</td>
<td class="text"> <span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue', window );">Aggregate intrinsic value, Outstanding beginning balance</a></td>
<td class="nump">$ 62,267,309<span></span>
</td>
<td class="nump">$ 140,132,451<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross', window );">Number of options, Granted</a></td>
<td class="nump">1,959,000<span></span>
</td>
<td class="nump">2,358,000<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice', window );">Weighted average exercise price, Granted</a></td>
<td class="nump">$ 9.30<span></span>
</td>
<td class="nump">$ 10.13<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue', window );">Weighted average grant date fair value, Granted</a></td>
<td class="nump">$ 6.60<span></span>
</td>
<td class="nump">$ 7.07<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod', window );">Number of options, Forfeited</a></td>
<td class="num">(257,083)<span></span>
</td>
<td class="num">(118,750)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice', window );">Weighted average exercise price, Forfeited</a></td>
<td class="nump">$ 12.00<span></span>
</td>
<td class="nump">$ 6.86<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice', window );">Weighted average grant date fair value, Forfeited</a></td>
<td class="nump">$ 6.74<span></span>
</td>
<td class="nump">$ 5.23<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised', window );">Number of options, Exercised</a></td>
<td class="num">(759,753)<span></span>
</td>
<td class="num">(400,537)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice', window );">Weighted average exercise price, Exercised</a></td>
<td class="nump">$ 2.34<span></span>
</td>
<td class="nump">$ 2.52<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice', window );">Weighted average grant date fair value, Exercised</a></td>
<td class="nump">$ 0.95<span></span>
</td>
<td class="nump">$ 1.88<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue', window );">Aggregate intrinsic value, Exercised</a></td>
<td class="nump">$ 4,629,026<span></span>
</td>
<td class="nump">$ 4,201,015<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber', window );">Number of options, Outstanding ending balance</a></td>
<td class="nump">14,111,780<span></span>
</td>
<td class="nump">13,169,616<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice', window );">Weighted average exercise price, Outstanding ending balance</a></td>
<td class="nump">$ 7.12<span></span>
</td>
<td class="nump">$ 6.61<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue', window );">Weighted average grant date fair value, Outstanding ending balance</a></td>
<td class="nump">$ 5.27<span></span>
</td>
<td class="nump">$ 4.96<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue', window );">Aggregate intrinsic value, Outstanding ending balance</a></td>
<td class="nump">$ 22,290,069<span></span>
</td>
<td class="nump">$ 62,267,309<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber', window );">Number of options, Exercisable</a></td>
<td class="nump">9,604,614<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice', window );">Weighted average exercise price, Exercisable</a></td>
<td class="nump">$ 5.19<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue', window );">Weighted average grant date fair value, Exercisable</a></td>
<td class="nump">$ 3.94<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1', window );">Aggregate intrinsic value, Exercisable</a></td>
<td class="nump">$ 22,290,069<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OffsettingAssetsLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OffsettingAssetsLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Per share or unit weighted-average fair value of nonvested award under share-based payment arrangement. Excludes share and unit options.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(2)(i)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(2)(ii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and currently exercisable under the stock option plan.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of accumulated difference between fair value of underlying shares on dates of exercise and exercise price on options exercised (or share units converted) into shares.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (d)(2)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The number of shares under options that were cancelled during the reporting period as a result of occurrence of a terminating event specified in contractual agreements pertaining to the stock option plan.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)(03)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Gross number of share options (or share units) granted during the period.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)(01)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (d)(1)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount by which the current fair value of the underlying stock exceeds the exercise price of options outstanding.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Number of options outstanding, including both vested and non-vested options.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(i)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(ii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(i)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(ii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Weighted average price at which option holders acquired shares when converting their stock options into shares.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)(02)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Weighted average price at which grantees could have acquired the underlying shares with respect to stock options that were terminated.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)(03)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Weighted average per share amount at which grantees can acquire shares of common stock by exercise of options.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)(01)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of difference between fair value of the underlying shares reserved for issuance and exercise price of vested portions of options outstanding and currently exercisable.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Weighted average grant-date fair value of non-vested options outstanding.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Number of share options (or share units) exercised during the current period.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -SubTopic 10<br> -Topic 505<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481112/505-10-50-2<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)(02)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(28))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 505<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480008/505-10-S99-1<br><br>Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 210<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_StockOptionMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=us-gaap_StockOptionMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>44
<FILENAME>R28.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649476465168">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Commitments and Contingencies (Details 4) - $ / shares<br></strong></div></th>
<th class="th" colspan="2">12 Months Ended</th>
<th class="th" colspan="1"></th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OffsettingAssetsLineItems', window );"><strong>Offsetting Assets [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2', window );">Weighted average remaining contractual life</a></td>
<td class="text">6 years<span></span>
</td>
<td class="text">6 years 4 months 24 days<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_StockOptionMember', window );">Equity Option [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OffsettingAssetsLineItems', window );"><strong>Offsetting Assets [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber', window );">Number of outstanding options</a></td>
<td class="nump">14,111,780<span></span>
</td>
<td class="nump">13,169,616<span></span>
</td>
<td class="nump">11,330,903<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2', window );">Weighted average remaining contractual life</a></td>
<td class="text">6 years 14 days<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice', window );">Weighted average exercise price</a></td>
<td class="nump">$ 7.12<span></span>
</td>
<td class="nump">$ 6.61<span></span>
</td>
<td class="nump">$ 5.74<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares', window );">Number of vested options</a></td>
<td class="nump">9,604,614<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice', window );">Weighted average exercise price options vested</a></td>
<td class="nump">$ 5.19<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_StockOptionMember', window );">Equity Option [Member] | Option Price 1 [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OffsettingAssetsLineItems', window );"><strong>Offsetting Assets [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit', window );">Range of exercise prices, Lower range limit</a></td>
<td class="nump">0.92<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit', window );">Range of exercise prices, Upper range limit</a></td>
<td class="nump">$ 3.00<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber', window );">Number of outstanding options</a></td>
<td class="nump">3,280,309<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2', window );">Weighted average remaining contractual life</a></td>
<td class="text">4 years 8 months 26 days<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice', window );">Weighted average exercise price</a></td>
<td class="nump">$ 2.39<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares', window );">Number of vested options</a></td>
<td class="nump">3,280,309<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice', window );">Weighted average exercise price options vested</a></td>
<td class="nump">$ 2.39<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_StockOptionMember', window );">Equity Option [Member] | Option Price 2 [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OffsettingAssetsLineItems', window );"><strong>Offsetting Assets [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit', window );">Range of exercise prices, Lower range limit</a></td>
<td class="nump">3.01<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit', window );">Range of exercise prices, Upper range limit</a></td>
<td class="nump">$ 5.00<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber', window );">Number of outstanding options</a></td>
<td class="nump">2,017,500<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2', window );">Weighted average remaining contractual life</a></td>
<td class="text">4 years 3 months 25 days<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice', window );">Weighted average exercise price</a></td>
<td class="nump">$ 3.28<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares', window );">Number of vested options</a></td>
<td class="nump">2,017,500<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice', window );">Weighted average exercise price options vested</a></td>
<td class="nump">$ 3.28<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_StockOptionMember', window );">Equity Option [Member] | Option Price 3 [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OffsettingAssetsLineItems', window );"><strong>Offsetting Assets [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit', window );">Range of exercise prices, Lower range limit</a></td>
<td class="nump">5.01<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit', window );">Range of exercise prices, Upper range limit</a></td>
<td class="nump">$ 9.00<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber', window );">Number of outstanding options</a></td>
<td class="nump">5,260,054<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2', window );">Weighted average remaining contractual life</a></td>
<td class="text">6 years 2 months 15 days<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice', window );">Weighted average exercise price</a></td>
<td class="nump">$ 6.90<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares', window );">Number of vested options</a></td>
<td class="nump">3,304,137<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice', window );">Weighted average exercise price options vested</a></td>
<td class="nump">$ 6.10<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_StockOptionMember', window );">Equity Option [Member] | Option Price 4 [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OffsettingAssetsLineItems', window );"><strong>Offsetting Assets [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit', window );">Range of exercise prices, Lower range limit</a></td>
<td class="nump">9.01<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit', window );">Range of exercise prices, Upper range limit</a></td>
<td class="nump">$ 13.00<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber', window );">Number of outstanding options</a></td>
<td class="nump">1,981,917<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2', window );">Weighted average remaining contractual life</a></td>
<td class="text">8 years 4 months 13 days<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice', window );">Weighted average exercise price</a></td>
<td class="nump">$ 10.55<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares', window );">Number of vested options</a></td>
<td class="nump">480,584<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice', window );">Weighted average exercise price options vested</a></td>
<td class="nump">$ 11.45<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_StockOptionMember', window );">Equity Option [Member] | Option Price 5 [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OffsettingAssetsLineItems', window );"><strong>Offsetting Assets [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit', window );">Range of exercise prices, Lower range limit</a></td>
<td class="nump">13.01<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit', window );">Range of exercise prices, Upper range limit</a></td>
<td class="nump">$ 25.00<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber', window );">Number of outstanding options</a></td>
<td class="nump">1,572,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2', window );">Weighted average remaining contractual life</a></td>
<td class="text">7 years 5 months 26 days<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice', window );">Weighted average exercise price</a></td>
<td class="nump">$ 18.29<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares', window );">Number of vested options</a></td>
<td class="nump">522,084<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice', window );">Weighted average exercise price options vested</a></td>
<td class="nump">$ 18.57<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OffsettingAssetsLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OffsettingAssetsLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Number of options outstanding, including both vested and non-vested options.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(i)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(ii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(i)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(ii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Weighted-average exercise price, at which grantee can acquire shares reserved for issuance, for fully vested and expected to vest exercisable or convertible options. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (e)(2)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The floor of a customized range of exercise prices for purposes of disclosing shares potentially issuable under outstanding stock option awards on all stock option plans and other required information pertaining to awards in the customized range.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (g)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The ceiling of a customized range of exercise prices for purposes of disclosing shares potentially issuable under outstanding stock option awards on all stock option plans and other required information pertaining to awards in the customized range.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (g)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Weighted average remaining contractual term for option awards outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 718<br> -SubTopic 10<br> -Subparagraph (e)(1)<br> -Name Accounting Standards Codification<br> -Paragraph 2<br> -Section 50<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:durationItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Number of options vested.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_StockOptionMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=us-gaap_StockOptionMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis=avxl_OptionPrice1Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis=avxl_OptionPrice1Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis=avxl_OptionPrice2Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis=avxl_OptionPrice2Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis=avxl_OptionPrice3Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis=avxl_OptionPrice3Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis=avxl_OptionPrice4Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis=avxl_OptionPrice4Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis=avxl_OptionPrice5Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis=avxl_OptionPrice5Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>45
<FILENAME>R29.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649477620032">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Commitments and Contingencies (Details 5) - USD ($)<br> $ in Thousands</strong></div></th>
<th class="th" colspan="3">12 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_LossContingenciesLineItems', window );"><strong>Loss Contingencies [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensation', window );">Total share based compensation</a></td>
<td class="nump">$ 16,370<span></span>
</td>
<td class="nump">$ 18,379<span></span>
</td>
<td class="nump">$ 8,231<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeStatementLocationAxis=us-gaap_GeneralAndAdministrativeExpenseMember', window );">General and Administrative Expense [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_LossContingenciesLineItems', window );"><strong>Loss Contingencies [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensation', window );">Total share based compensation</a></td>
<td class="nump">5,558<span></span>
</td>
<td class="nump">7,129<span></span>
</td>
<td class="nump">3,571<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeStatementLocationAxis=us-gaap_ResearchAndDevelopmentExpenseMember', window );">Research and Development Expense [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_LossContingenciesLineItems', window );"><strong>Loss Contingencies [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensation', window );">Total share based compensation</a></td>
<td class="nump">$ 10,812<span></span>
</td>
<td class="nump">$ 11,250<span></span>
</td>
<td class="nump">$ 4,660<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LossContingenciesLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 460<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 3<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482425/460-10-50-3<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 450<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 1<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483076/450-20-50-1<br><br>Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 450<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483076/450-20-50-4<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 450<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483076/450-20-50-4<br><br>Reference 5: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 450<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 9<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483076/450-20-50-9<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 450<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 9<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483076/450-20-50-9<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LossContingenciesLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensation">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of noncash expense for share-based payment arrangement.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (a)<br> -SubTopic 10<br> -Topic 230<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-28<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensation</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeStatementLocationAxis=us-gaap_GeneralAndAdministrativeExpenseMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeStatementLocationAxis=us-gaap_GeneralAndAdministrativeExpenseMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeStatementLocationAxis=us-gaap_ResearchAndDevelopmentExpenseMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeStatementLocationAxis=us-gaap_ResearchAndDevelopmentExpenseMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>46
<FILENAME>R30.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649476316064">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Commitments and Contingencies (Details 6)<br></strong></div></th>
<th class="th" colspan="3">12 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CommitmentsAndContingenciesDisclosureAbstract', window );"><strong>Commitments and Contingencies Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate', window );">Risk-free interest rate</a></td>
<td class="nump">3.70%<span></span>
</td>
<td class="nump">3.11%<span></span>
</td>
<td class="nump">0.73%<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1', window );">Expected life of options (years)</a></td>
<td class="text">5 years 7 months 20 days<span></span>
</td>
<td class="text">5 years 6 months 25 days<span></span>
</td>
<td class="text">5 years 8 months 26 days<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate', window );">Annualized volatility</a></td>
<td class="nump">85.13%<span></span>
</td>
<td class="nump">84.17%<span></span>
</td>
<td class="nump">93.43%<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate', window );">Dividend rate</a></td>
<td class="nump">0.00%<span></span>
</td>
<td class="nump">0.00%<span></span>
</td>
<td class="nump">0.00%<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommitmentsAndContingenciesDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommitmentsAndContingenciesDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The estimated dividend rate (a percentage of the share price) to be paid (expected dividends) to holders of the underlying shares over the option's term.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (f)(2)(iii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:percentItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The estimated measure of the percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (f)(2)(ii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:percentItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The risk-free interest rate assumption that is used in valuing an option on its own shares.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (f)(2)(iv)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:percentItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Expected term of award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (f)(2)(i)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:durationItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>47
<FILENAME>R31.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649474916528">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Commitments and Contingencies (Details Narrative) - USD ($)<br> $ / shares in Units, $ in Millions</strong></div></th>
<th class="th" colspan="1"></th>
<th class="th" colspan="3">12 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Mar. 25, 2022</div></th>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems', window );"><strong>Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1', window );">Operating lease term</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">12 months<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ClassOfWarrantOrRightOutstanding', window );">Warrants outstanding</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">160,000<span></span>
</td>
<td class="nump">160,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_WarrantsOutstandingWeightedAverageExercise', window );">Warrants outstanding weighted average exercise price</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 3.72<span></span>
</td>
<td class="nump">$ 3.72<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_OptionIssued', window );">Option issued</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">3,849,917<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue', window );">Weighted average grant date fair value of options vested</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 3.94<span></span>
</td>
<td class="nump">$ 4.69<span></span>
</td>
<td class="nump">$ 2.54<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2', window );">Weighted average contractual life of options outstanding</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">6 years<span></span>
</td>
<td class="text">6 years 4 months 24 days<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2', window );">Options exercisable</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">4 years 9 months<span></span>
</td>
<td class="text">5 years 1 month 6 days<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_AllocatedShareBasedCompensationExpense', window );">Share based compensation</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 16.4<span></span>
</td>
<td class="nump">$ 18.4<span></span>
</td>
<td class="nump">$ 8.2<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions', window );">Remaining stock based compensation</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 14.1<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_PlanNameAxis=avxl_StockOptionPlan2015Member', window );">Stock Option Plan 2015 [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems', window );"><strong>Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance', window );">Maximum number of common shares reserved for future issuance</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">6,050,553<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_PlanNameAxis=avxl_StockOptionPlan2019Member', window );">Stock Option Plan 2019 [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems', window );"><strong>Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized', window );">Additional shares of common stock available for issuance</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">6,000,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_PlanNameAxis=avxl_StockOptionPlan2022Member', window );">Stock Option Plan 2022 [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems', window );"><strong>Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized', window );">Additional shares of common stock available for issuance</a></td>
<td class="nump">10,000,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod', window );">Option granted</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">406,453<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant', window );">Option available issue</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">6,661,535<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_OptionIssued">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_OptionIssued</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_WarrantsOutstandingWeightedAverageExercise">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_WarrantsOutstandingWeightedAverageExercise</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AllocatedShareBasedCompensationExpense">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB Topic 14.F)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479830/718-10-S99-1<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (h)(1)(i)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AllocatedShareBasedCompensationExpense</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ClassOfWarrantOrRightOutstanding">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Number of warrants or rights outstanding.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ClassOfWarrantOrRightOutstanding</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Aggregate number of common shares reserved for future issuance.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.29)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommonStockCapitalSharesReservedForFutureIssuance</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of cost to be recognized for option under share-based payment arrangement.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (i)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Weighted average remaining lease term for operating lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 842<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 55<br> -Paragraph 53<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479589/842-20-55-53<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 842<br> -SubTopic 20<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (g)(3)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147478964/842-20-50-4<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:durationItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The weighted average fair value as of grant date pertaining to an equity-based award plan other than a stock (or unit) option plan for which the grantee gained the right during the reporting period, by satisfying service and performance requirements, to receive or retain shares or units, other instruments, or cash in accordance with the terms of the arrangement.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(2)(iii)(02)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 35<br> -Paragraph 1D<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480483/718-10-35-1D<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 35<br> -Paragraph 3<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480483/718-10-35-3<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)(1)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)(2)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)(3)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(i)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(ii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)(01)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)(02)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)(03)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)(04)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(2)(i)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(2)(ii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(2)(iii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 17: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(2)(iii)(01)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(2)(iii)(02)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 19: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(2)(iii)(03)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 20: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (d)(1)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 21: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (d)(2)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 22: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (e)(1)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 23: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (e)(2)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 24: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (f)(2)(i)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 25: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (f)(2)(ii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 26: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (f)(2)(iii)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 27: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (f)(2)(iv)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br><br>Reference 28: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (f)(2)(v)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Number of additional shares authorized for issuance under share-based payment arrangement.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Net number of share options (or share units) granted during the period.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 718<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)(1)(iv)(01)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Weighted average remaining contractual term for option awards outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 718<br> -SubTopic 10<br> -Subparagraph (e)(1)<br> -Name Accounting Standards Codification<br> -Paragraph 2<br> -Section 50<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:durationItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Weighted average remaining contractual term of exercisable stock options, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 718<br> -SubTopic 10<br> -Subparagraph (e)(2)<br> -Name Accounting Standards Codification<br> -Paragraph 2<br> -Section 50<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:durationItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PlanNameAxis=avxl_StockOptionPlan2015Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PlanNameAxis=avxl_StockOptionPlan2015Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PlanNameAxis=avxl_StockOptionPlan2019Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PlanNameAxis=avxl_StockOptionPlan2019Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PlanNameAxis=avxl_StockOptionPlan2022Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PlanNameAxis=avxl_StockOptionPlan2022Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>48
<FILENAME>R32.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649480260080">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Income Taxes (Details) - USD ($)<br> $ in Thousands</strong></div></th>
<th class="th" colspan="3">12 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxDisclosureAbstract', window );"><strong>Income Tax Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic', window );">United States</a></td>
<td class="num">$ (41,198)<span></span>
</td>
<td class="num">$ (40,002)<span></span>
</td>
<td class="num">$ (28,851)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign', window );">Foreign</a></td>
<td class="num">(6,300)<span></span>
</td>
<td class="num">(7,618)<span></span>
</td>
<td class="num">(8,790)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest', window );">Total</a></td>
<td class="num">$ (47,498)<span></span>
</td>
<td class="num">$ (47,620)<span></span>
</td>
<td class="num">$ (37,641)<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The portion of earnings or loss from continuing operations before income taxes that is attributable to domestic operations.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(h)(1))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480678/235-10-S99-1<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB Topic 6.I.Fact.3)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479360/740-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of income (loss) from continuing operations, including income (loss) from equity method investments, before deduction of income tax expense (benefit), and income (loss) attributable to noncontrolling interest.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 944<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(11))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483586/944-220-S99-1<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 22<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-22<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-30<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (f)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32<br><br>Reference 5: http://www.xbrl.org/2003/role/exampleRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 31<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-31<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 280<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 942<br> -SubTopic 235<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-05(b)(2))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479557/942-235-S99-1<br><br>Reference 8: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 25<br> -Paragraph 1<br> -SubTopic 20<br> -Topic 940<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147481913/940-20-25-1<br><br>Reference 9: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(10))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483621/220-10-S99-2<br><br>Reference 10: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 942<br> -SubTopic 220<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(15))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483589/942-220-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The portion of earnings or loss from continuing operations before income taxes that is attributable to foreign operations, which is defined as Income or Loss generated from operations located outside the entity's country of domicile.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(h)(1))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480678/235-10-S99-1<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB Topic 6.I.Fact.3)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479360/740-10-S99-1<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>49
<FILENAME>R33.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649473943696">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Income Taxes (Details 1) - USD ($)<br> $ in Thousands</strong></div></th>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxDisclosureAbstract', window );"><strong>Income Tax Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards', window );">Net operating loss carryforwards</a></td>
<td class="nump">$ 46,462<span></span>
</td>
<td class="nump">$ 46,208<span></span>
</td>
<td class="nump">$ 34,982<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment', window );">Research and development tax credit carryforwards</a></td>
<td class="nump">2,713<span></span>
</td>
<td class="nump">2,182<span></span>
</td>
<td class="nump">1,577<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost', window );">Stock-based compensation</a></td>
<td class="nump">18,593<span></span>
</td>
<td class="nump">13,373<span></span>
</td>
<td class="nump">10,453<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_DeferredTaxAssetsResearchAndDevelopmentCapitalization', window );">Research and development capitalization</a></td>
<td class="nump">7,219<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_DeferredTaxAssetsUnpaidCharges', window );">Unpaid charges</a></td>
<td class="nump">1,559<span></span>
</td>
<td class="nump">894<span></span>
</td>
<td class="nump">89<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets', window );">Intangible asset costs</a></td>
<td class="nump">593<span></span>
</td>
<td class="nump">388<span></span>
</td>
<td class="nump">323<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DeferredTaxAssetsUnrealizedCurrencyLosses', window );">Foreign exchange and other</a></td>
<td class="nump">49<span></span>
</td>
<td class="nump">44<span></span>
</td>
<td class="nump">62<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DeferredTaxAssetsValuationAllowance', window );">Valuation allowance of deferred tax assets</a></td>
<td class="num">(77,188)<span></span>
</td>
<td class="num">(63,089)<span></span>
</td>
<td class="num">(47,486)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DeferredTaxAssetsNet', window );">Net deferred tax assets</a></td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_DeferredTaxAssetsResearchAndDevelopmentCapitalization">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_DeferredTaxAssetsResearchAndDevelopmentCapitalization</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_DeferredTaxAssetsUnpaidCharges">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_DeferredTaxAssetsUnpaidCharges</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from intangible assets including goodwill.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from in-process research and development costs expensed in connection with a business combination.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 6<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-6<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-8<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DeferredTaxAssetsNet">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount after allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DeferredTaxAssetsNet</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 6<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-6<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-8<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DeferredTaxAssetsOperatingLossCarryforwards</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from share-based compensation.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 6<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-6<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-8<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DeferredTaxAssetsUnrealizedCurrencyLosses">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from unrealized losses on foreign currency transactions.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 6<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-6<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-8<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DeferredTaxAssetsUnrealizedCurrencyLosses</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DeferredTaxAssetsValuationAllowance">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DeferredTaxAssetsValuationAllowance</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>50
<FILENAME>R34.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649477452400">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Income Taxes (Details 2) - USD ($)<br> $ in Thousands</strong></div></th>
<th class="th" colspan="3">12 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxDisclosureAbstract', window );"><strong>Income Tax Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate', window );">Income tax benefit at statutory federal rate</a></td>
<td class="num">$ (9,975)<span></span>
</td>
<td class="num">$ (10,000)<span></span>
</td>
<td class="num">$ (7,934)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential', window );">Foreign income taxed at other rates</a></td>
<td class="text"> <span></span>
</td>
<td class="num">(170)<span></span>
</td>
<td class="num">(353)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_PermanentDifferencesRelatingToStockBasedCompensation', window );">Permanent differences relating to stock based compensation</a></td>
<td class="num">(601)<span></span>
</td>
<td class="num">(714)<span></span>
</td>
<td class="num">(4,379)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_EffectiveIncomeTaxRateReconciliationGiltiAmount', window );">Permanent differences relating to GILTI inclusion</a></td>
<td class="nump">165<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_PermanentDifferencesRelatingToSection162m', window );">Permanent differences relating to Section 162(m)</a></td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">816<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxReconciliationOtherAdjustments', window );">Other permanent differences</a></td>
<td class="nump">273<span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">741<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_AdjustmentToTaxAssetsBasedOnSection382', window );">Adjustment to tax assets based on Section 382</a></td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">3,330<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet', window );">Research and development credits, net</a></td>
<td class="num">(37)<span></span>
</td>
<td class="nump">232<span></span>
</td>
<td class="nump">1,042<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes', window );">State and local taxes</a></td>
<td class="num">(4,122)<span></span>
</td>
<td class="num">(4,975)<span></span>
</td>
<td class="num">(7,022)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxReconciliationPriorYearIncomeTaxes', window );">Adjustment to true up to prior years' tax provision</a></td>
<td class="nump">206<span></span>
</td>
<td class="nump">24<span></span>
</td>
<td class="nump">48<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate', window );">Effect of change in statutory tax rates</a></td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
<td class="nump">216<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_TaxesExcludingIncomeAndExciseTaxes', window );">State minimum and excise taxes</a></td>
<td class="text"> <span></span>
</td>
<td class="nump">358<span></span>
</td>
<td class="nump">268<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance', window );">Change in valuation allowances</a></td>
<td class="nump">14,098<span></span>
</td>
<td class="nump">15,603<span></span>
</td>
<td class="nump">13,495<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DeferredIncomeTaxExpenseBenefit', window );">Income tax expense</a></td>
<td class="nump">$ 7<span></span>
</td>
<td class="nump">$ 358<span></span>
</td>
<td class="nump">$ 268<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_AdjustmentToTaxAssetsBasedOnSection382">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_AdjustmentToTaxAssetsBasedOnSection382</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_PermanentDifferencesRelatingToSection162m">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_PermanentDifferencesRelatingToSection162m</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_PermanentDifferencesRelatingToStockBasedCompensation">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_PermanentDifferencesRelatingToStockBasedCompensation</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DeferredIncomeTaxExpenseBenefit">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of deferred income tax expense (benefit) pertaining to income (loss) from continuing operations.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (b)<br> -SubTopic 10<br> -Topic 230<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482740/230-10-45-28<br><br>Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 235<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(h)(1)(Note 1))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147480678/235-10-S99-1<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB Topic 6.I.Fact.2)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479360/740-10-S99-1<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB Topic 6.I.Fact.1)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479360/740-10-S99-1<br><br>Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB Topic 6.I.7)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147479360/740-10-S99-1<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 9<br> -Subparagraph (b)<br> -SubTopic 10<br> -Topic 740<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-9<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DeferredIncomeTaxExpenseBenefit</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EffectiveIncomeTaxRateReconciliationGiltiAmount">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of reported income tax expense from difference to expected income tax expense (benefit) computed by applying domestic federal statutory income tax rate to pretax income (loss) from continuing operations, attributable to global intangible low-taxed income (GILTI).</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 12<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-12<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EffectiveIncomeTaxRateReconciliationGiltiAmount</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to increase (decrease) in the valuation allowance for deferred tax assets.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 12<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-12<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations, attributable to increase (decrease) in the income tax rates.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 12<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-12<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 45<br> -Paragraph 15<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482525/740-10-45-15<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to foreign income tax expense (benefit).</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 12<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-12<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The amount of income tax expense or benefit for the period computed by applying the domestic federal statutory tax rates to pretax income from continuing operations.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 12<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-12<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxReconciliationOtherAdjustments">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to other adjustments.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 12<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-12<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxReconciliationOtherAdjustments</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxReconciliationPriorYearIncomeTaxes">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to revisions of previously reported income tax expense (benefit).</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 12<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-12<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxReconciliationPriorYearIncomeTaxes</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to state and local income tax expense (benefit).</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 12<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-12<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_TaxesExcludingIncomeAndExciseTaxes">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>All taxes not related to income of the entity or excise or sales taxes levied on the revenue of the entity that are not reported elsewhere. These taxes could include production, real estate, personal property, and pump tax.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 220<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(4))<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147483621/220-10-S99-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_TaxesExcludingIncomeAndExciseTaxes</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>51
<FILENAME>R35.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.23.3</span><table class="report" border="0" cellspacing="2" id="idm140649478632272">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Income Taxes (Details Narrative) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th" colspan="3">12 Months Ended</th>
<th class="th" colspan="1"></th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2023</div></th>
<th class="th"><div>Sep. 30, 2022</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2015</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OperatingLossCarryforwardsLineItems', window );"><strong>Operating Loss Carryforwards [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OperatingLossCarryforwards', window );">Operating loss carryforwards</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 2.5<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_OperatingLossCarryForwardsExpirationYear', window );">Operating loss carry forwards expiration year</a></td>
<td class="text">2036<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment', window );">Research and Development tax credits</a></td>
<td class="nump">$ 2.7<span></span>
</td>
<td class="nump">$ 2.2<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_ResearchAndDevelopmentTaxCreditsYear', window );">Research and development tax credits year</a></td>
<td class="text">2029<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DeferredTaxAssetsGross', window );">Gross deferred tax asset</a></td>
<td class="nump">$ 7.2<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch', window );">Research and development tax credit carryforwards</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0.8<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount', window );">Decrease in valuation allowance</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">3.3<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxAuthorityAxis=avxl_FederalMember', window );">Federal [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OperatingLossCarryforwardsLineItems', window );"><strong>Operating Loss Carryforwards [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OperatingLossCarryforwards', window );">Operating loss carryforwards</a></td>
<td class="nump">$ 126.3<span></span>
</td>
<td class="nump">123.4<span></span>
</td>
<td class="nump">$ 12.1<span></span>
</td>
<td class="nump">$ 25.8<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_avxl_OperatingLossCarryforwardsDescription', window );">Operating loss carryforwards description</a></td>
<td class="text">$37.7 million will begin to expire in 2025 and $88.6 million can be carried forward indefinitely<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxAuthorityAxis=us-gaap_StateAndLocalJurisdictionMember', window );">State and Local Jurisdiction [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OperatingLossCarryforwardsLineItems', window );"><strong>Operating Loss Carryforwards [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OperatingLossCarryforwards', window );">Operating loss carryforwards</a></td>
<td class="nump">$ 16.6<span></span>
</td>
<td class="nump">17.2<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxAuthorityAxis=us-gaap_ForeignCountryMember', window );">Foreign Tax Authority [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OperatingLossCarryforwardsLineItems', window );"><strong>Operating Loss Carryforwards [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OperatingLossCarryforwards', window );">Operating loss carryforwards</a></td>
<td class="nump">12.9<span></span>
</td>
<td class="nump">10.6<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_IncomeTaxAuthorityAxis=us-gaap_ForeignCountryMember', window );">Foreign Tax Authority [Member] | Australia, Dollars</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OperatingLossCarryforwardsLineItems', window );"><strong>Operating Loss Carryforwards [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_us-gaap_OperatingLossCarryforwards', window );">Operating loss carryforwards</a></td>
<td class="nump">$ 20.1<span></span>
</td>
<td class="nump">$ 14.9<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_OperatingLossCarryForwardsExpirationYear">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_OperatingLossCarryForwardsExpirationYear</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_OperatingLossCarryforwardsDescription">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_OperatingLossCarryforwardsDescription</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_avxl_ResearchAndDevelopmentTaxCreditsYear">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">avxl_ResearchAndDevelopmentTaxCreditsYear</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>avxl_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DeferredTaxAssetsGross">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (b)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DeferredTaxAssetsGross</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount before allocation of valuation allowances of deferred tax asset attributable to deductible research tax credit carryforwards.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 6<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-6<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-8<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-3<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to nondeductible research and development expense.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 12<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-12<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OperatingLossCarryforwards">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of operating loss carryforward, before tax effects, available to reduce future taxable income under enacted tax laws.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (a)<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-3<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OperatingLossCarryforwards</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OperatingLossCarryforwardsLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OperatingLossCarryforwardsLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Amount of increase (decrease) in the valuation allowance for a specified deferred tax asset.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Topic 740<br> -SubTopic 10<br> -Name Accounting Standards Codification<br> -Section 50<br> -Paragraph 2<br> -Publisher FASB<br> -URI https://asc.fasb.org//1943274/2147482685/740-10-50-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxAuthorityAxis=avxl_FederalMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxAuthorityAxis=avxl_FederalMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxAuthorityAxis=us-gaap_StateAndLocalJurisdictionMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxAuthorityAxis=us-gaap_StateAndLocalJurisdictionMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxAuthorityAxis=us-gaap_ForeignCountryMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxAuthorityAxis=us-gaap_ForeignCountryMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_CurrencyAxis=currency_AUD">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_CurrencyAxis=currency_AUD</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>52
<FILENAME>e5240_10k_htm.xml
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<XML>
<?xml version="1.0" encoding="utf-8"?>
<xbrl
  xmlns="http://www.xbrl.org/2003/instance"
  xmlns:avxl="http://anavex.com/20230930"
  xmlns:currency="http://xbrl.sec.gov/currency/2023"
  xmlns:dei="http://xbrl.sec.gov/dei/2023"
  xmlns:iso4217="http://www.xbrl.org/2003/iso4217"
  xmlns:link="http://www.xbrl.org/2003/linkbase"
  xmlns:srt="http://fasb.org/srt/2023"
  xmlns:us-gaap="http://fasb.org/us-gaap/2023"
  xmlns:xbrldi="http://xbrl.org/2006/xbrldi"
  xmlns:xlink="http://www.w3.org/1999/xlink"
  xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <link:schemaRef xlink:href="avxl-20230930.xsd" xlink:type="simple"/>
    <context id="From2022-10-01to2023-09-30">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="AsOf2023-03-31">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
        </entity>
        <period>
            <instant>2023-03-31</instant>
        </period>
    </context>
    <context id="AsOf2023-11-24">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
        </entity>
        <period>
            <instant>2023-11-24</instant>
        </period>
    </context>
    <context id="AsOf2023-09-30">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="AsOf2022-09-30">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
        </entity>
        <period>
            <instant>2022-09-30</instant>
        </period>
    </context>
    <context id="From2021-10-012022-09-30">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2022-09-30</endDate>
        </period>
    </context>
    <context id="From2020-10-012021-09-30">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
        </entity>
        <period>
            <startDate>2020-10-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="AsOf2021-09-30">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="AsOf2020-09-30">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
        </entity>
        <period>
            <instant>2020-09-30</instant>
        </period>
    </context>
    <context id="AsOf2020-09-30_us-gaap_CommonStockMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-09-30</instant>
        </period>
    </context>
    <context id="AsOf2020-09-30_us-gaap_AdditionalPaidInCapitalMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-09-30</instant>
        </period>
    </context>
    <context id="AsOf2020-09-30_us-gaap_RetainedEarningsMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-09-30</instant>
        </period>
    </context>
    <context id="AsOf2021-09-30_us-gaap_CommonStockMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="AsOf2021-09-30_us-gaap_AdditionalPaidInCapitalMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="AsOf2021-09-30_us-gaap_RetainedEarningsMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="AsOf2022-09-30_us-gaap_CommonStockMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2022-09-30</instant>
        </period>
    </context>
    <context id="AsOf2022-09-30_us-gaap_AdditionalPaidInCapitalMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2022-09-30</instant>
        </period>
    </context>
    <context id="AsOf2022-09-30_us-gaap_RetainedEarningsMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2022-09-30</instant>
        </period>
    </context>
    <context id="From2020-10-012021-09-30_us-gaap_CommonStockMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-10-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-10-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-10-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="From2021-10-012022-09-30_us-gaap_CommonStockMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2022-09-30</endDate>
        </period>
    </context>
    <context id="From2021-10-012022-09-30_us-gaap_AdditionalPaidInCapitalMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2022-09-30</endDate>
        </period>
    </context>
    <context id="From2021-10-012022-09-30_us-gaap_RetainedEarningsMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2022-09-30</endDate>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_us-gaap_CommonStockMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_us-gaap_AdditionalPaidInCapitalMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_us-gaap_RetainedEarningsMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="AsOf2023-09-30_us-gaap_CommonStockMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="AsOf2023-09-30_us-gaap_AdditionalPaidInCapitalMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="AsOf2023-09-30_us-gaap_RetainedEarningsMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="From2020-10-012021-09-30_custom_MichaelJFoxFoundationMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:RelatedPartyTransactionsByRelatedPartyAxis">avxl:MichaelJFoxFoundationMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-10-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_currency_AUD">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:AUD</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="From2021-10-012022-09-30_currency_AUD">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:AUD</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2022-09-30</endDate>
        </period>
    </context>
    <context id="From2020-10-012021-09-30_currency_AUD">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:AUD</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-10-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="AsOf2023-09-30_currency_AUD">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:AUD</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="AsOf2022-09-30_currency_AUD">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:AUD</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2022-09-30</instant>
        </period>
    </context>
    <context id="From2021-06-212021-06-22_custom_SecuritiesPurchaseAgreementMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:SecuritiesPurchaseAgreementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-06-21</startDate>
            <endDate>2021-06-22</endDate>
        </period>
    </context>
    <context id="AsOf2021-06-22_custom_SecuritiesPurchaseAgreementMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:SecuritiesPurchaseAgreementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-06-22</instant>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_custom_EquityOfferingSalesAgreementMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:EquityOfferingSalesAgreementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="From2021-10-012022-09-30_custom_EquityOfferingSalesAgreementMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:EquityOfferingSalesAgreementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2022-09-30</endDate>
        </period>
    </context>
    <context id="From2020-10-012021-09-30_custom_EquityOfferingSalesAgreementMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:EquityOfferingSalesAgreementMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-10-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="From2023-02-022023-02-03_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-02-02</startDate>
            <endDate>2023-02-03</endDate>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockIncludingCommitmentSharesMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommonStockIncludingCommitmentSharesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockIncludingCommitmentSharesMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommonStockIncludingCommitmentSharesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2022-09-30</endDate>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockExcludingCommitmentSharesMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommonStockExcludingCommitmentSharesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockExcludingCommitmentSharesMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommonStockExcludingCommitmentSharesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2022-09-30</endDate>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2022-09-30</endDate>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommitmentSharesMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommitmentSharesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommitmentSharesMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommitmentSharesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2023Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2022-09-30</endDate>
        </period>
    </context>
    <context id="From2023-02-022023-02-03_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2019Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2023-02-02</startDate>
            <endDate>2023-02-03</endDate>
        </period>
    </context>
    <context id="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockIncludingCommitmentSharesMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommonStockIncludingCommitmentSharesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2019Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-10-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockExcludingCommitmentSharesMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommonStockExcludingCommitmentSharesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2019Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-10-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_us-gaap_CommonStockMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2019Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-10-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_custom_CommitmentSharesMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">avxl:CommitmentSharesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2019Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-10-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2019Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="From2021-10-012022-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">avxl:PurchaseAgreement2019Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:LegalEntityAxis">avxl:LincolnParkCapitalFundLLCMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2022-09-30</endDate>
        </period>
    </context>
    <context id="AsOf2023-09-30_custom_StockOptionPlan2015Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis">avxl:StockOptionPlan2015Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_custom_StockOptionPlan2019Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis">avxl:StockOptionPlan2019Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="From2021-10-012022-09-30_custom_StockOptionPlan2022Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis">avxl:StockOptionPlan2022Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2022-09-30</endDate>
        </period>
    </context>
    <context id="From2022-03-242022-03-25_custom_StockOptionPlan2022Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis">avxl:StockOptionPlan2022Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-03-24</startDate>
            <endDate>2022-03-25</endDate>
        </period>
    </context>
    <context id="AsOf2023-09-30_custom_StockOptionPlan2022Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis">avxl:StockOptionPlan2022Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="AsOf2023-09-30_custom_PurchaseWarrants1Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis">avxl:PurchaseWarrants1Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="AsOf2023-09-30_custom_PurchaseWarrants2Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis">avxl:PurchaseWarrants2Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="AsOf2021-09-30_us-gaap_StockOptionMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="From2021-10-012022-09-30_us-gaap_StockOptionMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2022-09-30</endDate>
        </period>
    </context>
    <context id="AsOf2022-09-30_us-gaap_StockOptionMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2022-09-30</instant>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_us-gaap_StockOptionMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="AsOf2023-09-30_us-gaap_StockOptionMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice1Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice1Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice2Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice2Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice3Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice3Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice4Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice4Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice5Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:StockOptionMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis">avxl:OptionPrice5Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_us-gaap_GeneralAndAdministrativeExpenseMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis">us-gaap:GeneralAndAdministrativeExpenseMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="From2021-10-012022-09-30_us-gaap_GeneralAndAdministrativeExpenseMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis">us-gaap:GeneralAndAdministrativeExpenseMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2022-09-30</endDate>
        </period>
    </context>
    <context id="From2020-10-012021-09-30_us-gaap_GeneralAndAdministrativeExpenseMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis">us-gaap:GeneralAndAdministrativeExpenseMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-10-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_us-gaap_ResearchAndDevelopmentExpenseMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis">us-gaap:ResearchAndDevelopmentExpenseMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="From2021-10-012022-09-30_us-gaap_ResearchAndDevelopmentExpenseMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis">us-gaap:ResearchAndDevelopmentExpenseMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2022-09-30</endDate>
        </period>
    </context>
    <context id="From2020-10-012021-09-30_us-gaap_ResearchAndDevelopmentExpenseMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis">us-gaap:ResearchAndDevelopmentExpenseMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-10-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="AsOf2023-09-30_custom_FederalMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">avxl:FederalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="AsOf2022-09-30_custom_FederalMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">avxl:FederalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2022-09-30</instant>
        </period>
    </context>
    <context id="From2022-10-012023-09-30_custom_FederalMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">avxl:FederalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2022-10-01</startDate>
            <endDate>2023-09-30</endDate>
        </period>
    </context>
    <context id="AsOf2023-09-30_us-gaap_StateAndLocalJurisdictionMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">us-gaap:StateAndLocalJurisdictionMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="AsOf2022-09-30_us-gaap_StateAndLocalJurisdictionMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">us-gaap:StateAndLocalJurisdictionMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2022-09-30</instant>
        </period>
    </context>
    <context id="AsOf2023-09-30_us-gaap_ForeignCountryMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">us-gaap:ForeignCountryMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="AsOf2023-09-30_us-gaap_ForeignCountryMember_currency_AUD">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:AUD</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">us-gaap:ForeignCountryMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2023-09-30</instant>
        </period>
    </context>
    <context id="AsOf2022-09-30_us-gaap_ForeignCountryMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">us-gaap:ForeignCountryMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2022-09-30</instant>
        </period>
    </context>
    <context id="AsOf2022-09-30_us-gaap_ForeignCountryMember_currency_AUD">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:AUD</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">us-gaap:ForeignCountryMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2022-09-30</instant>
        </period>
    </context>
    <context id="AsOf2015-09-30_custom_FederalMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">avxl:FederalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2015-09-30</instant>
        </period>
    </context>
    <context id="AsOf2021-09-30_custom_FederalMember">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001314052</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis">avxl:FederalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <unit id="USD">
        <measure>iso4217:USD</measure>
    </unit>
    <unit id="Shares">
        <measure>shares</measure>
    </unit>
    <unit id="USDPShares">
        <divide>
            <unitNumerator>
                <measure>iso4217:USD</measure>
            </unitNumerator>
            <unitDenominator>
                <measure>shares</measure>
            </unitDenominator>
        </divide>
    </unit>
    <unit id="Pure">
        <measure>pure</measure>
    </unit>
    <dei:AmendmentFlag contextRef="From2022-10-01to2023-09-30">false</dei:AmendmentFlag>
    <dei:DocumentFiscalYearFocus contextRef="From2022-10-01to2023-09-30">2023</dei:DocumentFiscalYearFocus>
    <dei:DocumentFiscalPeriodFocus contextRef="From2022-10-01to2023-09-30">FY</dei:DocumentFiscalPeriodFocus>
    <dei:EntityCentralIndexKey contextRef="From2022-10-01to2023-09-30">0001314052</dei:EntityCentralIndexKey>
    <us-gaap:CommitmentsAndContingencies
      contextRef="AsOf2023-09-30"
      id="xdx2ixbrl0084"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:CommitmentsAndContingencies
      contextRef="AsOf2022-09-30"
      id="xdx2ixbrl0085"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:PreferredStockValue
      contextRef="AsOf2023-09-30"
      id="xdx2ixbrl0095"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:PreferredStockValue
      contextRef="AsOf2022-09-30"
      id="xdx2ixbrl0097"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:NonOperatingIncomeFromGrants
      contextRef="From2021-10-012022-09-30"
      id="xdx2ixbrl0156"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:OtherFinancingExpense
      contextRef="From2021-10-012022-09-30"
      id="xdx2ixbrl0168"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:OtherFinancingExpense
      contextRef="From2020-10-012021-09-30"
      id="xdx2ixbrl0169"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:NoncashFinancingRelatedCharges
      contextRef="From2021-10-012022-09-30"
      id="xdx2ixbrl0236"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:NoncashFinancingRelatedCharges
      contextRef="From2020-10-012021-09-30"
      id="xdx2ixbrl0237"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:DeferredGrantIncome
      contextRef="From2021-10-012022-09-30"
      id="xdx2ixbrl0264"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:PaymentsOfStockIssuanceCosts
      contextRef="From2022-10-01to2023-09-30"
      id="xdx2ixbrl0279"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:ProceedsFromWarrantExercises
      contextRef="From2022-10-01to2023-09-30"
      id="xdx2ixbrl0283"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:ProceedsFromWarrantExercises
      contextRef="From2021-10-012022-09-30"
      id="xdx2ixbrl0284"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0324"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="From2020-10-012021-09-30"
      id="xdx2ixbrl0325"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:CommitmentShares
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      id="xdx2ixbrl0329"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:CommitmentShares
      contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember"
      id="xdx2ixbrl0330"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:CommitmentShares
      contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0331"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:CommitmentShares
      contextRef="From2020-10-012021-09-30"
      id="xdx2ixbrl0332"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:SharesIssuedUnderSalesAgreement
      contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0338"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:LessSalesAgreementShareIssueCosts
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      id="xdx2ixbrl0343"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:LessSalesAgreementShareIssueCosts
      contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0345"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:SharesIssuedPursuantToRegisteredDirectOffering
      contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0350"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:LessRegisteredDirectOfferingShareIssueCosts
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      id="xdx2ixbrl0355"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:LessRegisteredDirectOfferingShareIssueCosts
      contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0357"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:SharesIssuedPursuantToExerciseOfStockOptions
      contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0362"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:SharesIssuedPusuantToExerciseOfWarrants
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      id="xdx2ixbrl0367"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:SharesIssuedPusuantToExerciseOfWarrants
      contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0369"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      id="xdx2ixbrl0374"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0376"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:NetIncomeLoss
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      id="xdx2ixbrl0379"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:NetIncomeLoss
      contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember"
      id="xdx2ixbrl0380"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:SharesIssuedUnderSalesAgreement
      contextRef="From2021-10-012022-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0393"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:LessSalesAgreementShareIssueCosts
      contextRef="From2021-10-012022-09-30_us-gaap_CommonStockMember"
      id="xdx2ixbrl0398"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:LessSalesAgreementShareIssueCosts
      contextRef="From2021-10-012022-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0400"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:SharesIssuedPursuantToExerciseOfStockOptions
      contextRef="From2021-10-012022-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0405"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="From2021-10-012022-09-30_us-gaap_CommonStockMember"
      id="xdx2ixbrl0410"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="From2021-10-012022-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0412"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:NetIncomeLoss
      contextRef="From2021-10-012022-09-30_us-gaap_CommonStockMember"
      id="xdx2ixbrl0415"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:NetIncomeLoss
      contextRef="From2021-10-012022-09-30_us-gaap_AdditionalPaidInCapitalMember"
      id="xdx2ixbrl0416"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares
      contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember"
      id="xdx2ixbrl0427"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares
      contextRef="From2022-10-012023-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0429"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="From2022-10-012023-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0436"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:CommitmentShares
      contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember"
      id="xdx2ixbrl0441"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:CommitmentShares
      contextRef="From2022-10-012023-09-30_us-gaap_AdditionalPaidInCapitalMember"
      id="xdx2ixbrl0442"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:CommitmentShares
      contextRef="From2022-10-012023-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0443"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:CommitmentShares
      contextRef="From2022-10-01to2023-09-30"
      id="xdx2ixbrl0444"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:SharesIssuedPursuantToExerciseOfStockOptions
      contextRef="From2022-10-012023-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0450"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember"
      id="xdx2ixbrl0455"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="From2022-10-012023-09-30_us-gaap_RetainedEarningsMember"
      id="xdx2ixbrl0457"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:NetIncomeLoss
      contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember"
      id="xdx2ixbrl0460"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:NetIncomeLoss
      contextRef="From2022-10-012023-09-30_us-gaap_AdditionalPaidInCapitalMember"
      id="xdx2ixbrl0461"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
      contextRef="AsOf2021-09-30_us-gaap_StockOptionMember"
      id="xdx2ixbrl0768"
      unitRef="USDPShares"
      xsi:nil="true"/>
    <avxl:DeferredTaxAssetsResearchAndDevelopmentCapitalization
      contextRef="AsOf2022-09-30"
      id="xdx2ixbrl1029"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:DeferredTaxAssetsResearchAndDevelopmentCapitalization
      contextRef="AsOf2021-09-30"
      id="xdx2ixbrl1030"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:DeferredTaxAssetsNet
      contextRef="AsOf2023-09-30"
      id="xdx2ixbrl1048"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:DeferredTaxAssetsNet
      contextRef="AsOf2022-09-30"
      id="xdx2ixbrl1049"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:DeferredTaxAssetsNet
      contextRef="AsOf2021-09-30"
      id="xdx2ixbrl1050"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:IncomeTaxReconciliationForeignIncomeTaxRateDifferential
      contextRef="From2022-10-01to2023-09-30"
      id="xdx2ixbrl1058"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:EffectiveIncomeTaxRateReconciliationGiltiAmount
      contextRef="From2021-10-012022-09-30"
      id="xdx2ixbrl1067"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:EffectiveIncomeTaxRateReconciliationGiltiAmount
      contextRef="From2020-10-012021-09-30"
      id="xdx2ixbrl1068"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:PermanentDifferencesRelatingToSection162m
      contextRef="From2022-10-01to2023-09-30"
      id="xdx2ixbrl1070"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:PermanentDifferencesRelatingToSection162m
      contextRef="From2021-10-012022-09-30"
      id="xdx2ixbrl1071"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:IncomeTaxReconciliationOtherAdjustments
      contextRef="From2021-10-012022-09-30"
      id="xdx2ixbrl1075"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:AdjustmentToTaxAssetsBasedOnSection382
      contextRef="From2022-10-01to2023-09-30"
      id="xdx2ixbrl1078"
      unitRef="USD"
      xsi:nil="true"/>
    <avxl:AdjustmentToTaxAssetsBasedOnSection382
      contextRef="From2021-10-012022-09-30"
      id="xdx2ixbrl1079"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:IncomeTaxReconciliationChangeInEnactedTaxRate
      contextRef="From2022-10-01to2023-09-30"
      id="xdx2ixbrl1094"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:IncomeTaxReconciliationChangeInEnactedTaxRate
      contextRef="From2021-10-012022-09-30"
      id="xdx2ixbrl1095"
      unitRef="USD"
      xsi:nil="true"/>
    <us-gaap:TaxesExcludingIncomeAndExciseTaxes
      contextRef="From2022-10-01to2023-09-30"
      id="xdx2ixbrl1098"
      unitRef="USD"
      xsi:nil="true"/>
    <dei:DocumentType contextRef="From2022-10-01to2023-09-30">10-K</dei:DocumentType>
    <dei:DocumentAnnualReport contextRef="From2022-10-01to2023-09-30">true</dei:DocumentAnnualReport>
    <dei:DocumentPeriodEndDate contextRef="From2022-10-01to2023-09-30">2023-09-30</dei:DocumentPeriodEndDate>
    <dei:CurrentFiscalYearEndDate contextRef="From2022-10-01to2023-09-30">--09-30</dei:CurrentFiscalYearEndDate>
    <dei:DocumentTransitionReport contextRef="From2022-10-01to2023-09-30">false</dei:DocumentTransitionReport>
    <dei:EntityFileNumber contextRef="From2022-10-01to2023-09-30">001-37606</dei:EntityFileNumber>
    <dei:EntityRegistrantName contextRef="From2022-10-01to2023-09-30">ANAVEX LIFE SCIENCES CORP.</dei:EntityRegistrantName>
    <dei:EntityIncorporationStateCountryCode contextRef="From2022-10-01to2023-09-30">NV</dei:EntityIncorporationStateCountryCode>
    <dei:EntityTaxIdentificationNumber contextRef="From2022-10-01to2023-09-30">98-0608404</dei:EntityTaxIdentificationNumber>
    <dei:EntityAddressAddressLine1 contextRef="From2022-10-01to2023-09-30">630 5th Avenue</dei:EntityAddressAddressLine1>
    <dei:EntityAddressAddressLine2 contextRef="From2022-10-01to2023-09-30">20th Floor</dei:EntityAddressAddressLine2>
    <dei:EntityAddressCityOrTown contextRef="From2022-10-01to2023-09-30">New York</dei:EntityAddressCityOrTown>
    <dei:EntityAddressStateOrProvince contextRef="From2022-10-01to2023-09-30">NY</dei:EntityAddressStateOrProvince>
    <dei:EntityAddressCountry contextRef="From2022-10-01to2023-09-30">US</dei:EntityAddressCountry>
    <dei:EntityAddressPostalZipCode contextRef="From2022-10-01to2023-09-30">10111</dei:EntityAddressPostalZipCode>
    <dei:CityAreaCode contextRef="From2022-10-01to2023-09-30">844</dei:CityAreaCode>
    <dei:LocalPhoneNumber contextRef="From2022-10-01to2023-09-30">689-3939</dei:LocalPhoneNumber>
    <dei:Security12bTitle contextRef="From2022-10-01to2023-09-30">Common     Stock, $0.001 par value</dei:Security12bTitle>
    <dei:TradingSymbol contextRef="From2022-10-01to2023-09-30">AVXL</dei:TradingSymbol>
    <dei:SecurityExchangeName contextRef="From2022-10-01to2023-09-30">NASDAQ</dei:SecurityExchangeName>
    <dei:EntityWellKnownSeasonedIssuer contextRef="From2022-10-01to2023-09-30">Yes</dei:EntityWellKnownSeasonedIssuer>
    <dei:EntityVoluntaryFilers contextRef="From2022-10-01to2023-09-30">No</dei:EntityVoluntaryFilers>
    <dei:EntityCurrentReportingStatus contextRef="From2022-10-01to2023-09-30">Yes</dei:EntityCurrentReportingStatus>
    <dei:EntityInteractiveDataCurrent contextRef="From2022-10-01to2023-09-30">Yes</dei:EntityInteractiveDataCurrent>
    <dei:EntityFilerCategory contextRef="From2022-10-01to2023-09-30">Large Accelerated Filer</dei:EntityFilerCategory>
    <dei:EntitySmallBusiness contextRef="From2022-10-01to2023-09-30">false</dei:EntitySmallBusiness>
    <dei:EntityEmergingGrowthCompany contextRef="From2022-10-01to2023-09-30">false</dei:EntityEmergingGrowthCompany>
    <dei:IcfrAuditorAttestationFlag contextRef="From2022-10-01to2023-09-30">true</dei:IcfrAuditorAttestationFlag>
    <dei:DocumentFinStmtErrorCorrectionFlag contextRef="From2022-10-01to2023-09-30">false</dei:DocumentFinStmtErrorCorrectionFlag>
    <dei:EntityShellCompany contextRef="From2022-10-01to2023-09-30">false</dei:EntityShellCompany>
    <dei:EntityPublicFloat contextRef="AsOf2023-03-31" decimals="-6" unitRef="USD">667000000</dei:EntityPublicFloat>
    <dei:EntityCommonStockSharesOutstanding contextRef="AsOf2023-11-24" decimals="INF" unitRef="Shares">82086511</dei:EntityCommonStockSharesOutstanding>
    <dei:AuditorName contextRef="From2022-10-01to2023-09-30">GRANT THORNTON LLP</dei:AuditorName>
    <dei:AuditorLocation contextRef="From2022-10-01to2023-09-30">Melville, New York</dei:AuditorLocation>
    <dei:AuditorFirmId contextRef="From2022-10-01to2023-09-30">248</dei:AuditorFirmId>
    <us-gaap:CashAndCashEquivalentsAtCarryingValue contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">151024000</us-gaap:CashAndCashEquivalentsAtCarryingValue>
    <us-gaap:CashAndCashEquivalentsAtCarryingValue contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">149158000</us-gaap:CashAndCashEquivalentsAtCarryingValue>
    <us-gaap:IncomeTaxesReceivable contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">2709000</us-gaap:IncomeTaxesReceivable>
    <us-gaap:IncomeTaxesReceivable contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">3193000</us-gaap:IncomeTaxesReceivable>
    <us-gaap:PrepaidExpenseAndOtherAssetsCurrent contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">653000</us-gaap:PrepaidExpenseAndOtherAssetsCurrent>
    <us-gaap:PrepaidExpenseAndOtherAssetsCurrent contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">354000</us-gaap:PrepaidExpenseAndOtherAssetsCurrent>
    <us-gaap:Assets contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">154386000</us-gaap:Assets>
    <us-gaap:Assets contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">152705000</us-gaap:Assets>
    <us-gaap:AccountsPayableCurrent contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">4322000</us-gaap:AccountsPayableCurrent>
    <us-gaap:AccountsPayableCurrent contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">3825000</us-gaap:AccountsPayableCurrent>
    <us-gaap:AccruedLiabilitiesCurrent contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">7295000</us-gaap:AccruedLiabilitiesCurrent>
    <us-gaap:AccruedLiabilitiesCurrent contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">5945000</us-gaap:AccruedLiabilitiesCurrent>
    <us-gaap:DeferredRentCredit contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">917000</us-gaap:DeferredRentCredit>
    <us-gaap:DeferredRentCredit contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">444000</us-gaap:DeferredRentCredit>
    <us-gaap:Liabilities contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">12534000</us-gaap:Liabilities>
    <us-gaap:Liabilities contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">10214000</us-gaap:Liabilities>
    <us-gaap:PreferredStockSharesAuthorized contextRef="AsOf2023-09-30" decimals="INF" unitRef="Shares">10000000</us-gaap:PreferredStockSharesAuthorized>
    <us-gaap:PreferredStockSharesAuthorized contextRef="AsOf2022-09-30" decimals="INF" unitRef="Shares">10000000</us-gaap:PreferredStockSharesAuthorized>
    <us-gaap:PreferredStockParOrStatedValuePerShare
      contextRef="AsOf2023-09-30"
      decimals="INF"
      unitRef="USDPShares">0.001</us-gaap:PreferredStockParOrStatedValuePerShare>
    <us-gaap:PreferredStockParOrStatedValuePerShare
      contextRef="AsOf2022-09-30"
      decimals="INF"
      unitRef="USDPShares">0.001</us-gaap:PreferredStockParOrStatedValuePerShare>
    <us-gaap:CommonStockSharesAuthorized contextRef="AsOf2023-09-30" decimals="INF" unitRef="Shares">200000000</us-gaap:CommonStockSharesAuthorized>
    <us-gaap:CommonStockSharesAuthorized contextRef="AsOf2022-09-30" decimals="INF" unitRef="Shares">200000000</us-gaap:CommonStockSharesAuthorized>
    <us-gaap:CommonStockParOrStatedValuePerShare
      contextRef="AsOf2023-09-30"
      decimals="INF"
      unitRef="USDPShares">0.001</us-gaap:CommonStockParOrStatedValuePerShare>
    <us-gaap:CommonStockParOrStatedValuePerShare
      contextRef="AsOf2022-09-30"
      decimals="INF"
      unitRef="USDPShares">0.001</us-gaap:CommonStockParOrStatedValuePerShare>
    <us-gaap:CommonStockSharesIssued contextRef="AsOf2023-09-30" decimals="INF" unitRef="Shares">82066511</us-gaap:CommonStockSharesIssued>
    <us-gaap:CommonStockSharesOutstanding contextRef="AsOf2023-09-30" decimals="INF" unitRef="Shares">82066511</us-gaap:CommonStockSharesOutstanding>
    <us-gaap:CommonStockSharesIssued contextRef="AsOf2022-09-30" decimals="INF" unitRef="Shares">77942815</us-gaap:CommonStockSharesIssued>
    <us-gaap:CommonStockSharesOutstanding contextRef="AsOf2022-09-30" decimals="INF" unitRef="Shares">77942815</us-gaap:CommonStockSharesOutstanding>
    <us-gaap:CommonStockValue contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">82000</us-gaap:CommonStockValue>
    <us-gaap:CommonStockValue contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">78000</us-gaap:CommonStockValue>
    <us-gaap:AdditionalPaidInCapitalCommonStock contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">434839000</us-gaap:AdditionalPaidInCapitalCommonStock>
    <us-gaap:AdditionalPaidInCapitalCommonStock contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">387977000</us-gaap:AdditionalPaidInCapitalCommonStock>
    <us-gaap:RetainedEarningsAccumulatedDeficit contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">-293069000</us-gaap:RetainedEarningsAccumulatedDeficit>
    <us-gaap:RetainedEarningsAccumulatedDeficit contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">-245564000</us-gaap:RetainedEarningsAccumulatedDeficit>
    <us-gaap:StockholdersEquity contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">141852000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">142491000</us-gaap:StockholdersEquity>
    <us-gaap:LiabilitiesAndStockholdersEquity contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">154386000</us-gaap:LiabilitiesAndStockholdersEquity>
    <us-gaap:LiabilitiesAndStockholdersEquity contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">152705000</us-gaap:LiabilitiesAndStockholdersEquity>
    <us-gaap:GeneralAndAdministrativeExpense
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">12039000</us-gaap:GeneralAndAdministrativeExpense>
    <us-gaap:GeneralAndAdministrativeExpense
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">13070000</us-gaap:GeneralAndAdministrativeExpense>
    <us-gaap:GeneralAndAdministrativeExpense
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">9018000</us-gaap:GeneralAndAdministrativeExpense>
    <us-gaap:ResearchAndDevelopmentExpense
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">43717000</us-gaap:ResearchAndDevelopmentExpense>
    <us-gaap:ResearchAndDevelopmentExpense
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">37916000</us-gaap:ResearchAndDevelopmentExpense>
    <us-gaap:ResearchAndDevelopmentExpense
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">32984000</us-gaap:ResearchAndDevelopmentExpense>
    <us-gaap:OperatingExpenses
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">55756000</us-gaap:OperatingExpenses>
    <us-gaap:OperatingExpenses
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">50986000</us-gaap:OperatingExpenses>
    <us-gaap:OperatingExpenses
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">42002000</us-gaap:OperatingExpenses>
    <us-gaap:OperatingIncomeLoss
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-55756000</us-gaap:OperatingIncomeLoss>
    <us-gaap:OperatingIncomeLoss
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-50986000</us-gaap:OperatingIncomeLoss>
    <us-gaap:OperatingIncomeLoss
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-42002000</us-gaap:OperatingIncomeLoss>
    <avxl:NonOperatingIncomeFromGrants
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">25000</avxl:NonOperatingIncomeFromGrants>
    <avxl:NonOperatingIncomeFromGrants
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">54000</avxl:NonOperatingIncomeFromGrants>
    <avxl:ResearchAndDevelopmentIncentiveIncome
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">2718000</avxl:ResearchAndDevelopmentIncentiveIncome>
    <avxl:ResearchAndDevelopmentIncentiveIncome
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">3323000</avxl:ResearchAndDevelopmentIncentiveIncome>
    <avxl:ResearchAndDevelopmentIncentiveIncome
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">4547000</avxl:ResearchAndDevelopmentIncentiveIncome>
    <us-gaap:InterestIncomeExpenseNet
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">6519000</us-gaap:InterestIncomeExpenseNet>
    <us-gaap:InterestIncomeExpenseNet
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">947000</us-gaap:InterestIncomeExpenseNet>
    <us-gaap:InterestIncomeExpenseNet
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">26000</us-gaap:InterestIncomeExpenseNet>
    <avxl:OtherFinancingExpense
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">964000</avxl:OtherFinancingExpense>
    <us-gaap:ForeignCurrencyTransactionGainLossBeforeTax
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-40000</us-gaap:ForeignCurrencyTransactionGainLossBeforeTax>
    <us-gaap:ForeignCurrencyTransactionGainLossBeforeTax
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-904000</us-gaap:ForeignCurrencyTransactionGainLossBeforeTax>
    <us-gaap:ForeignCurrencyTransactionGainLossBeforeTax
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-266000</us-gaap:ForeignCurrencyTransactionGainLossBeforeTax>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">8258000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">3366000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">4361000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-47498000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-47620000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-37641000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest>
    <us-gaap:CurrentIncomeTaxExpenseBenefit
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">7000</us-gaap:CurrentIncomeTaxExpenseBenefit>
    <us-gaap:CurrentIncomeTaxExpenseBenefit
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">358000</us-gaap:CurrentIncomeTaxExpenseBenefit>
    <us-gaap:CurrentIncomeTaxExpenseBenefit
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">268000</us-gaap:CurrentIncomeTaxExpenseBenefit>
    <us-gaap:NetIncomeLoss
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-47505000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-47978000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-37909000</us-gaap:NetIncomeLoss>
    <us-gaap:EarningsPerShareBasic
      contextRef="From2022-10-01to2023-09-30"
      decimals="INF"
      unitRef="USDPShares">-0.60</us-gaap:EarningsPerShareBasic>
    <us-gaap:EarningsPerShareDiluted
      contextRef="From2022-10-01to2023-09-30"
      decimals="INF"
      unitRef="USDPShares">-0.60</us-gaap:EarningsPerShareDiluted>
    <us-gaap:EarningsPerShareBasic
      contextRef="From2021-10-012022-09-30"
      decimals="INF"
      unitRef="USDPShares">-0.62</us-gaap:EarningsPerShareBasic>
    <us-gaap:EarningsPerShareDiluted
      contextRef="From2021-10-012022-09-30"
      decimals="INF"
      unitRef="USDPShares">-0.62</us-gaap:EarningsPerShareDiluted>
    <us-gaap:EarningsPerShareBasic
      contextRef="From2020-10-012021-09-30"
      decimals="INF"
      unitRef="USDPShares">-0.54</us-gaap:EarningsPerShareBasic>
    <us-gaap:EarningsPerShareDiluted
      contextRef="From2020-10-012021-09-30"
      decimals="INF"
      unitRef="USDPShares">-0.54</us-gaap:EarningsPerShareDiluted>
    <us-gaap:WeightedAverageNumberOfSharesOutstandingBasic
      contextRef="From2022-10-01to2023-09-30"
      decimals="INF"
      unitRef="Shares">79787596</us-gaap:WeightedAverageNumberOfSharesOutstandingBasic>
    <us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding
      contextRef="From2022-10-01to2023-09-30"
      decimals="INF"
      unitRef="Shares">79787596</us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding>
    <us-gaap:WeightedAverageNumberOfSharesOutstandingBasic
      contextRef="From2021-10-012022-09-30"
      decimals="INF"
      unitRef="Shares">76909993</us-gaap:WeightedAverageNumberOfSharesOutstandingBasic>
    <us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding
      contextRef="From2021-10-012022-09-30"
      decimals="INF"
      unitRef="Shares">76909993</us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding>
    <us-gaap:WeightedAverageNumberOfSharesOutstandingBasic
      contextRef="From2020-10-012021-09-30"
      decimals="INF"
      unitRef="Shares">69802960</us-gaap:WeightedAverageNumberOfSharesOutstandingBasic>
    <us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding
      contextRef="From2020-10-012021-09-30"
      decimals="INF"
      unitRef="Shares">69802960</us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding>
    <us-gaap:NetIncomeLoss
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-47505000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-47978000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-37909000</us-gaap:NetIncomeLoss>
    <avxl:NoncashFinancingRelatedCharges
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">845000</avxl:NoncashFinancingRelatedCharges>
    <us-gaap:ShareBasedCompensation
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">16370000</us-gaap:ShareBasedCompensation>
    <us-gaap:ShareBasedCompensation
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">18379000</us-gaap:ShareBasedCompensation>
    <us-gaap:ShareBasedCompensation
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">8231000</us-gaap:ShareBasedCompensation>
    <us-gaap:IncreaseDecreaseInIncomeTaxesReceivable
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-484000</us-gaap:IncreaseDecreaseInIncomeTaxesReceivable>
    <us-gaap:IncreaseDecreaseInIncomeTaxesReceivable
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-5944000</us-gaap:IncreaseDecreaseInIncomeTaxesReceivable>
    <us-gaap:IncreaseDecreaseInIncomeTaxesReceivable
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">4287000</us-gaap:IncreaseDecreaseInIncomeTaxesReceivable>
    <us-gaap:IncreaseDecreaseInPrepaidExpense
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">299000</us-gaap:IncreaseDecreaseInPrepaidExpense>
    <us-gaap:IncreaseDecreaseInPrepaidExpense
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-1000</us-gaap:IncreaseDecreaseInPrepaidExpense>
    <us-gaap:IncreaseDecreaseInPrepaidExpense
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-88000</us-gaap:IncreaseDecreaseInPrepaidExpense>
    <us-gaap:IncreaseDecreaseInAccountsPayable
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">497000</us-gaap:IncreaseDecreaseInAccountsPayable>
    <us-gaap:IncreaseDecreaseInAccountsPayable
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-914000</us-gaap:IncreaseDecreaseInAccountsPayable>
    <us-gaap:IncreaseDecreaseInAccountsPayable
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">751000</us-gaap:IncreaseDecreaseInAccountsPayable>
    <us-gaap:IncreaseDecreaseInAccruedLiabilities
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">1350000</us-gaap:IncreaseDecreaseInAccruedLiabilities>
    <us-gaap:IncreaseDecreaseInAccruedLiabilities
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">330000</us-gaap:IncreaseDecreaseInAccruedLiabilities>
    <us-gaap:IncreaseDecreaseInAccruedLiabilities
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">2298000</us-gaap:IncreaseDecreaseInAccruedLiabilities>
    <avxl:DeferredGrantIncome
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-473000</avxl:DeferredGrantIncome>
    <avxl:DeferredGrantIncome
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-444000</avxl:DeferredGrantIncome>
    <us-gaap:NetCashProvidedByUsedInOperatingActivities
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-27785000</us-gaap:NetCashProvidedByUsedInOperatingActivities>
    <us-gaap:NetCashProvidedByUsedInOperatingActivities
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-24238000</us-gaap:NetCashProvidedByUsedInOperatingActivities>
    <us-gaap:NetCashProvidedByUsedInOperatingActivities
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-30384000</us-gaap:NetCashProvidedByUsedInOperatingActivities>
    <us-gaap:ProceedsFromIssuanceOfCommonStock
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">27875000</us-gaap:ProceedsFromIssuanceOfCommonStock>
    <us-gaap:ProceedsFromIssuanceOfCommonStock
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">20985000</us-gaap:ProceedsFromIssuanceOfCommonStock>
    <us-gaap:ProceedsFromIssuanceOfCommonStock
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">153219000</us-gaap:ProceedsFromIssuanceOfCommonStock>
    <us-gaap:PaymentsOfStockIssuanceCosts
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">707000</us-gaap:PaymentsOfStockIssuanceCosts>
    <us-gaap:PaymentsOfStockIssuanceCosts
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">5551000</us-gaap:PaymentsOfStockIssuanceCosts>
    <us-gaap:ProceedsFromWarrantExercises
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">1467000</us-gaap:ProceedsFromWarrantExercises>
    <us-gaap:ProceedsFromStockOptionsExercised
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">1776000</us-gaap:ProceedsFromStockOptionsExercised>
    <us-gaap:ProceedsFromStockOptionsExercised
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">1010000</us-gaap:ProceedsFromStockOptionsExercised>
    <us-gaap:ProceedsFromStockOptionsExercised
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">4108000</us-gaap:ProceedsFromStockOptionsExercised>
    <us-gaap:NetCashProvidedByUsedInFinancingActivities
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">29651000</us-gaap:NetCashProvidedByUsedInFinancingActivities>
    <us-gaap:NetCashProvidedByUsedInFinancingActivities
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">21288000</us-gaap:NetCashProvidedByUsedInFinancingActivities>
    <us-gaap:NetCashProvidedByUsedInFinancingActivities
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">153243000</us-gaap:NetCashProvidedByUsedInFinancingActivities>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">1866000</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-2950000</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">122859000</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">149158000</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents contextRef="AsOf2021-09-30" decimals="-3" unitRef="USD">152108000</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents contextRef="AsOf2020-09-30" decimals="-3" unitRef="USD">29249000</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">151024000</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">149158000</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents contextRef="AsOf2021-09-30" decimals="-3" unitRef="USD">152108000</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <avxl:CashPaidForStateAndLocalMinimumIncomeTaxes
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">136000</avxl:CashPaidForStateAndLocalMinimumIncomeTaxes>
    <avxl:CashPaidForStateAndLocalMinimumIncomeTaxes
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">327000</avxl:CashPaidForStateAndLocalMinimumIncomeTaxes>
    <avxl:CashPaidForStateAndLocalMinimumIncomeTaxes
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">140000</avxl:CashPaidForStateAndLocalMinimumIncomeTaxes>
    <us-gaap:SharesOutstanding
      contextRef="AsOf2020-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">62045198</us-gaap:SharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="AsOf2020-09-30_us-gaap_CommonStockMember"
      decimals="-3"
      unitRef="USD">62000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="AsOf2020-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">186852000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="AsOf2020-09-30_us-gaap_RetainedEarningsMember"
      decimals="-3"
      unitRef="USD">-159677000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity contextRef="AsOf2020-09-30" decimals="-3" unitRef="USD">27237000</us-gaap:StockholdersEquity>
    <us-gaap:StockRepurchasedDuringPeriodShares
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">4007996</us-gaap:StockRepurchasedDuringPeriodShares>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      decimals="-3"
      unitRef="USD">4000</us-gaap:StockRepurchasedDuringPeriodValue>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">24107000</us-gaap:StockRepurchasedDuringPeriodValue>
    <avxl:CommitmentSharesShares
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">78213</avxl:CommitmentSharesShares>
    <avxl:SharesIssuedUnderSalesAgreementShares
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">5634576</avxl:SharesIssuedUnderSalesAgreementShares>
    <avxl:SharesIssuedUnderSalesAgreement
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      decimals="-3"
      unitRef="USD">6000</avxl:SharesIssuedUnderSalesAgreement>
    <avxl:SharesIssuedUnderSalesAgreement
      contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">79102000</avxl:SharesIssuedUnderSalesAgreement>
    <avxl:SharesIssuedUnderSalesAgreement
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">79108000</avxl:SharesIssuedUnderSalesAgreement>
    <avxl:LessSalesAgreementShareIssueCosts
      contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">-2438000</avxl:LessSalesAgreementShareIssueCosts>
    <avxl:LessSalesAgreementShareIssueCosts
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-2438000</avxl:LessSalesAgreementShareIssueCosts>
    <avxl:SharesIssuedPursuantToRegisteredDirectOfferingShares
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">2380953</avxl:SharesIssuedPursuantToRegisteredDirectOfferingShares>
    <avxl:SharesIssuedPursuantToRegisteredDirectOffering
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      decimals="-3"
      unitRef="USD">2000</avxl:SharesIssuedPursuantToRegisteredDirectOffering>
    <avxl:SharesIssuedPursuantToRegisteredDirectOffering
      contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">49998000</avxl:SharesIssuedPursuantToRegisteredDirectOffering>
    <avxl:SharesIssuedPursuantToRegisteredDirectOffering
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">50000000</avxl:SharesIssuedPursuantToRegisteredDirectOffering>
    <avxl:LessRegisteredDirectOfferingShareIssueCosts
      contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">-3097000</avxl:LessRegisteredDirectOfferingShareIssueCosts>
    <avxl:LessRegisteredDirectOfferingShareIssueCosts
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-3097000</avxl:LessRegisteredDirectOfferingShareIssueCosts>
    <avxl:SharesIssuedPursuantToExerciseOfStockOptionsShares
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">1421529</avxl:SharesIssuedPursuantToExerciseOfStockOptionsShares>
    <avxl:SharesIssuedPursuantToExerciseOfStockOptions
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      decimals="-3"
      unitRef="USD">1000</avxl:SharesIssuedPursuantToExerciseOfStockOptions>
    <avxl:SharesIssuedPursuantToExerciseOfStockOptions
      contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">4107000</avxl:SharesIssuedPursuantToExerciseOfStockOptions>
    <avxl:SharesIssuedPursuantToExerciseOfStockOptions
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">4108000</avxl:SharesIssuedPursuantToExerciseOfStockOptions>
    <avxl:SharesIssuedPusuantToExerciseOfWarrantsShares
      contextRef="From2020-10-012021-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">350000</avxl:SharesIssuedPusuantToExerciseOfWarrantsShares>
    <avxl:SharesIssuedPusuantToExerciseOfWarrants
      contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">1466000</avxl:SharesIssuedPusuantToExerciseOfWarrants>
    <avxl:SharesIssuedPusuantToExerciseOfWarrants
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">1466000</avxl:SharesIssuedPusuantToExerciseOfWarrants>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="From2020-10-012021-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">8231000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">8231000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:NetIncomeLoss
      contextRef="From2020-10-012021-09-30_us-gaap_RetainedEarningsMember"
      decimals="-3"
      unitRef="USD">-37909000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-37909000</us-gaap:NetIncomeLoss>
    <us-gaap:SharesOutstanding
      contextRef="AsOf2021-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">75918465</us-gaap:SharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="AsOf2021-09-30_us-gaap_CommonStockMember"
      decimals="-3"
      unitRef="USD">75000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="AsOf2021-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">348328000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="AsOf2021-09-30_us-gaap_RetainedEarningsMember"
      decimals="-3"
      unitRef="USD">-197586000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity contextRef="AsOf2021-09-30" decimals="-3" unitRef="USD">150817000</us-gaap:StockholdersEquity>
    <avxl:SharesIssuedUnderSalesAgreementShares
      contextRef="From2021-10-012022-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">1623813</avxl:SharesIssuedUnderSalesAgreementShares>
    <avxl:SharesIssuedUnderSalesAgreement
      contextRef="From2021-10-012022-09-30_us-gaap_CommonStockMember"
      decimals="-3"
      unitRef="USD">2000</avxl:SharesIssuedUnderSalesAgreement>
    <avxl:SharesIssuedUnderSalesAgreement
      contextRef="From2021-10-012022-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">20983000</avxl:SharesIssuedUnderSalesAgreement>
    <avxl:SharesIssuedUnderSalesAgreement
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">20985000</avxl:SharesIssuedUnderSalesAgreement>
    <avxl:LessSalesAgreementShareIssueCosts
      contextRef="From2021-10-012022-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">-723000</avxl:LessSalesAgreementShareIssueCosts>
    <avxl:LessSalesAgreementShareIssueCosts
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-723000</avxl:LessSalesAgreementShareIssueCosts>
    <avxl:SharesIssuedPursuantToExerciseOfStockOptionsShares
      contextRef="From2021-10-012022-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">400537</avxl:SharesIssuedPursuantToExerciseOfStockOptionsShares>
    <avxl:SharesIssuedPursuantToExerciseOfStockOptions
      contextRef="From2021-10-012022-09-30_us-gaap_CommonStockMember"
      decimals="-3"
      unitRef="USD">1000</avxl:SharesIssuedPursuantToExerciseOfStockOptions>
    <avxl:SharesIssuedPursuantToExerciseOfStockOptions
      contextRef="From2021-10-012022-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">1010000</avxl:SharesIssuedPursuantToExerciseOfStockOptions>
    <avxl:SharesIssuedPursuantToExerciseOfStockOptions
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">1011000</avxl:SharesIssuedPursuantToExerciseOfStockOptions>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="From2021-10-012022-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">18379000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">18379000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:NetIncomeLoss
      contextRef="From2021-10-012022-09-30_us-gaap_RetainedEarningsMember"
      decimals="-3"
      unitRef="USD">-47978000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-47978000</us-gaap:NetIncomeLoss>
    <us-gaap:SharesOutstanding
      contextRef="AsOf2022-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">77942815</us-gaap:SharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="AsOf2022-09-30_us-gaap_CommonStockMember"
      decimals="-3"
      unitRef="USD">78000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="AsOf2022-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">387977000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="AsOf2022-09-30_us-gaap_RetainedEarningsMember"
      decimals="-3"
      unitRef="USD">-245564000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">142491000</us-gaap:StockholdersEquity>
    <avxl:SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares
      contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">75000</avxl:SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares>
    <avxl:SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares
      contextRef="From2022-10-012023-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">845000</avxl:SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares>
    <avxl:SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">845000</avxl:SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares>
    <us-gaap:StockRepurchasedDuringPeriodShares
      contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">3275000</us-gaap:StockRepurchasedDuringPeriodShares>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember"
      decimals="-3"
      unitRef="USD">3000</us-gaap:StockRepurchasedDuringPeriodValue>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="From2022-10-012023-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">27872000</us-gaap:StockRepurchasedDuringPeriodValue>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">27875000</us-gaap:StockRepurchasedDuringPeriodValue>
    <avxl:CommitmentSharesShares
      contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">13943</avxl:CommitmentSharesShares>
    <avxl:SharesIssuedPursuantToExerciseOfStockOptionsShares
      contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">759753</avxl:SharesIssuedPursuantToExerciseOfStockOptionsShares>
    <avxl:SharesIssuedPursuantToExerciseOfStockOptions
      contextRef="From2022-10-012023-09-30_us-gaap_CommonStockMember"
      decimals="-3"
      unitRef="USD">1000</avxl:SharesIssuedPursuantToExerciseOfStockOptions>
    <avxl:SharesIssuedPursuantToExerciseOfStockOptions
      contextRef="From2022-10-012023-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">1775000</avxl:SharesIssuedPursuantToExerciseOfStockOptions>
    <avxl:SharesIssuedPursuantToExerciseOfStockOptions
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">1776000</avxl:SharesIssuedPursuantToExerciseOfStockOptions>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="From2022-10-012023-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">16370000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">16370000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:NetIncomeLoss
      contextRef="From2022-10-012023-09-30_us-gaap_RetainedEarningsMember"
      decimals="-3"
      unitRef="USD">-47505000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-47505000</us-gaap:NetIncomeLoss>
    <us-gaap:SharesOutstanding
      contextRef="AsOf2023-09-30_us-gaap_CommonStockMember"
      decimals="INF"
      unitRef="Shares">82066511</us-gaap:SharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="AsOf2023-09-30_us-gaap_CommonStockMember"
      decimals="-3"
      unitRef="USD">82000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="AsOf2023-09-30_us-gaap_AdditionalPaidInCapitalMember"
      decimals="-3"
      unitRef="USD">434839000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="AsOf2023-09-30_us-gaap_RetainedEarningsMember"
      decimals="-3"
      unitRef="USD">-293069000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">141852000</us-gaap:StockholdersEquity>
    <us-gaap:OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_80E_eus-gaap--OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_zzwO6whBvBu3" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;Note
1 	&lt;span id="xdx_827_zzKl0Cvv1eXc"&gt;Business Description and Basis of Presentation&lt;/span&gt; &lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;Business&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Anavex
Life Sciences Corp. (&#x201c;Anavex&#x201d; or the &#x201c;Company&#x201d;) is a clinical stage biopharmaceutical company engaged in the
development of differentiated therapeutics by applying precision medicine to central nervous system (&#x201c;CNS&#x201d;) diseases with
high unmet need. Anavex analyzes genomic data from clinical trials to identify biomarkers, which are used in the analysis of its clinical
trials for the treatment of neurodegenerative and neurodevelopmental diseases.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company&#x2019;s lead compound ANAVEX&lt;sup&gt;&#xae;&lt;/sup&gt;2-73 (blarcamesine) is being developed to treat Alzheimer&#x2019;s disease, Parkinson&#x2019;s
disease and potentially other central nervous system diseases, including rare diseases, such as Rett syndrome, a rare severe neurological
monogenic disorder caused by mutations in the X-linked gene, methyl-CpG-binding protein 2 (&#x201c;MECP2&#x201d;).&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;Basis
of Presentation &lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;These
consolidated financial statements have been prepared pursuant to the rules and regulations of the Securities and Exchange Commission
(&#x201c;SEC&#x201d;) and the instructions to Form 10-K and have been prepared under the accounting principles generally accepted in the
United States of America (&#x201c;U.S. GAAP&#x201d;).&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;Liquidity&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;All
of the Company&#x2019;s potential drug compounds are in the clinical development stage and the Company cannot be certain that its research
and development efforts will be successful or, if successful, that its potential drug compounds will ever be approved for sales to pharmaceutical
companies or generate commercial revenues. To date, we have not generated any revenues from our operations. The Company expects the business
to continue to experience negative cash flows from operations for the foreseeable future and cannot predict when, if ever, our business
might become profitable.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Management
believes that the current working capital position will be sufficient to meet the Company&#x2019;s working capital requirements beyond
the next 12 months after the date that these consolidated financial statements are issued. The process of drug development can be costly,
and the timing and outcomes of clinical trials are uncertain.&#160;The assumptions upon which the Company has based its estimates are
routinely evaluated and may be subject to change.&#160;The actual amount of the Company&#x2019;s expenditures will vary depending upon
a number of factors including but not limited to the design, timing and duration of future clinical trials, the progress of the Company&#x2019;s
research and development programs and the level of financial resources available. The Company has the ability to adjust its operating
plan spending levels based on the timing of future clinical trials.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Other
than our rights related to the Purchase Agreement (as defined below in Note 5), there can be no assurance that additional financing will
be available to us when needed or, if available, that it can be obtained on commercially reasonable terms. If the Company is not able
to obtain the additional financing on a timely basis, if and when it is needed, it will be forced to delay or scale down some or all
of its research and development activities.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</us-gaap:OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock>
    <us-gaap:SignificantAccountingPoliciesTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_809_eus-gaap--SignificantAccountingPoliciesTextBlock_zhJnQIuZqXN" style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;Note
2	&lt;span id="xdx_825_z0b09WgWKbRj"&gt;Summary of Significant Accounting Policies&lt;/span&gt; &lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p id="xdx_848_eus-gaap--UseOfEstimates_z6qiTKflTLI2" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_86B_zdIdNWMOYl8g"&gt;Use
of Estimates&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
preparation of financial statements in accordance with U.S. GAAP requires management to make estimates and assumptions that affect the
reported amounts of assets and liabilities at the date of the financial statements and the reported amounts of revenue and expenses in
the reporting period. The Company regularly evaluates estimates and assumptions related to accounting for research and development costs,
incentive income receivable, valuation and recoverability of deferred tax assets, stock based compensation, and loss contingencies. The
Company bases its estimates and assumptions on current facts, historical experience, and various other factors that it believes to be
reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and
liabilities and the accrual of costs and expenses that are not readily apparent from other sources. The actual results experienced by
the Company may differ materially and adversely from the Company&#x2019;s estimates. To the extent there are material differences between
the estimates and the actual results, future results of operations will be affected.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;







&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;/p&gt;








&lt;p id="xdx_84A_eus-gaap--ConsolidationPolicyTextBlock_z2ffcVZrWlFa" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_867_zBDDP2KxbUlg"&gt;Principles
of Consolidation&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;These
consolidated financial statements include the accounts of Anavex Life Sciences Corp. and its wholly-owned subsidiaries, Anavex Australia
Pty Limited (&#x201c;Anavex Australia&#x201d;), a company incorporated under the laws of Australia, Anavex Germany GmbH, a company incorporated
under the laws of Germany, and Anavex Canada Ltd., a company incorporated under the laws of the Province of Ontario, Canada. All inter-company
transactions and balances have been eliminated.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p id="xdx_842_eus-gaap--CashAndCashEquivalentsPolicyTextBlock_zD2psO58wgqi" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_860_zXnZYnJ3AxH9"&gt;Cash
and equivalents&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company considers only those investments which are highly liquid, readily convertible to cash and that mature within three months from
the date of purchase to be cash equivalents.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;Highly
liquid investments that are considered cash equivalents include money market&#160;accounts, money market&#160;funds&#160;and&#160;certificates
of deposit. The carrying value of cash equivalents approximates fair value due to the short-term maturity of these securities. The Company&#x2019;s
investment policy allows for investments in domestic money market certificates, certificates of deposit, money market funds, bonds or
commercial papers, and establishes diversification and credit quality requirements and limits investments by maturity and issuer. The
Company currently maintains its investments at one large well known financial institution.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;The
Company maintains its cash in bank deposit accounts which, at times, may exceed federally insured limits. Accounts are guaranteed by
the Federal Deposit Insurance Corporation (FDIC) up to $&lt;span id="xdx_90E_eus-gaap--CashFDICInsuredAmount_iI_c20230930_zOPrmEbs29Na" title="Federal deposit insurance corporation"&gt;250,000&lt;/span&gt; under current regulations. At September 30, 2023 and 2022, substantially
all of the Company&#x2019;s cash balances were in excess of these federally insured limits. The Company mitigates this risk by maintaining
the majority of its cash balances in a large well-known financial institution. The Company has not experienced any losses in such accounts.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p id="xdx_849_eus-gaap--ResearchAndDevelopmentExpensePolicy_znu0D1C47Tij" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_869_zOUCigTgWOAl"&gt;Research
and Development Expenses&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Research
and development costs are expensed as incurred. These expenses are comprised of the costs of the Company&#x2019;s proprietary research
and development efforts, including preclinical studies, clinical trials, manufacturing costs, employee salaries and benefits and stock-based
compensation expense, contract services including external research and development expenses incurred under arrangements with third parties
such as contract research organizations (&#x201c;CROs&#x201d;), facilities costs, overhead costs and other related expenses. Milestone
payments made by the Company to third parties are expensed when the specific milestone has been achieved. Manufacturing costs are expensed
as incurred in accordance with Accounting Standard Codification (&#x201c;ASC&#x201d;) 730, Research and Development, as these materials
have no alternative future use outside of their intended use.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Nonrefundable
advance payments for goods or services that will be used or rendered for future research and development activities are deferred and
amortized over the period that the goods are delivered, or the related services are performed, subject to an assessment of recoverability.
The Company makes estimates of costs incurred in relation to external CROs, and clinical site costs. When evaluating the adequacy of
the accrued liabilities, the Company analyzes progress of the trials and studies including the phase or completion of events, invoices
received and contracted costs. Judgments and estimates are made in determining the accrued balances at the end of any reporting period.
Actual results could differ from the Company&#x2019;s estimates. The Company&#x2019;s historical accrual estimates have not been materially
different from actual costs.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;







&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;/p&gt;








&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;In
addition, the Company incurs expenses in respect of intellectual property costs relating to patents and trademarks. The probability of
success and length of time to develop commercial applications of the drugs subject to the underlying patent and trademark costs is difficult
to determine and numerous risks and uncertainties exist with respect to the timely completion of the development projects. There is no
assurance the drugs subject to the underlying patents and trademarks will ever be successfully commercialized.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Due
to these risks and uncertainties, the patent and trademark costs do not meet the definition of an asset and thus are expensed as incurred
within general and administrative expenses.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p id="xdx_84A_eus-gaap--RevenueRecognitionIncentives_zXLfXylE6t0j" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_86F_zOf8tSfJTM19"&gt;Research
and Development Incentive Income&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company is eligible to obtain certain research and development tax credits, including, through its wholly owned subsidiary Anavex Australia,
the Australian research and development tax incentive credit (the &#x201c;Australia R&amp;amp;D credit&#x201d;) through a program administered
through the Australian Tax Office (the &#x201c;ATO&#x201d;) and AusIndustry, a division of the Australian Government&#x2019;s Department
of Industry, Innovation and Science (&#x201c;AusIndustry&#x201d;). The Australia R&amp;amp;D credit program provides for a cash refund based
on a percentage of eligible research and development activities undertaken in Australia by Anavex Australia. Anavex Australia is also
eligible under the Australia R&amp;amp;D credit program to receive the cash refund for certain research and development expenses incurred
by Anavex Australia outside of Australia, to the extent such expenses are pre-approved by AusIndustry pursuant to an advanced overseas
finding application.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Australia R&amp;amp;D credit program is available to eligible companies with an annual aggregate revenue of less than $20.0 million Australian
during the reimbursable period at a rate of 18.5% above the claimant&#x2019;s company tax rate in Australia.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
tax incentives are available on the basis of specific criteria with which the Company must comply. Although the tax incentive may be
administered through the local tax authority, the Company has accounted for the incentives outside of the scope of ASC Topic 740, Income
Taxes (&#x201c;ASC 740&#x201d;), since the incentives are not linked to the Company&#x2019;s taxable income and can be realized regardless
of whether the Company has generated taxable income in the respective jurisdictions.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;With
respect to the Australia R&amp;amp;D credit, as there is no authoritative guidance under GAAP for accounting for grants to for-profit business
entities, the Company accounts for the grant by analogy to IAS20 Accounting for Government Grants and Disclosure of Government Assistance
(&#x201c;IAS 20&#x201d;). The Company recognizes the Research and Development Incentive income as it incurs costs eligible for reimbursement
under the Australia R&amp;amp;D credit program when it is reasonably assured that the cash incentive will be received, as evidenced through
enrollment in the program and when the applicable conditions under the program have been met. The Company accrues for the amount of cash
refund it expects to receive in relation to research and development expenses outside of Australia only to the extent it has received
advanced approval from AusIndustry, pursuant to an approved advanced overseas finding application.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;In
addition, Anavex Australia and Anavex Canada incur Goods and Services Tax (GST) on certain services provided by local vendors. As a domestic
entity in those jurisdictions, Anavex Australia and Anavex Canada are entitled to a refund of the GST paid. Similarly, Anavex Germany
incurs Value Added Tax (VAT) on certain services provided by local vendors, to which it is entitled to a refund of such VAT paid. The
Company&#x2019;s estimate of the amount of cash refund it expects to receive related to GST and VAT incurred is included in Incentive
and tax receivables in the accompanying consolidated balance sheets.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p id="xdx_843_ecustom--LicenseFeesPolicyTextBlock_zbyGkTcneVC" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_867_zUYRjRzpeyi4"&gt;License
Fees&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;The
Company expenses amounts paid to acquire licenses associated with products under development when the ultimate recovery of the amounts
paid is uncertain and the technology has no alternative future use when acquired. Acquisitions of technology licenses are charged to
expense or capitalized based on management&#x2019;s assessment regarding the ultimate recoverability of the amounts paid and the potential
for alternative future use. The Company has determined that the technological feasibility for its product candidates is reached when
the requisite regulatory approvals are obtained to make the product available for sale.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;&#160;&lt;/span&gt;&lt;/p&gt;







&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;/p&gt;








&lt;p id="xdx_84A_eus-gaap--EarningsPerSharePolicyTextBlock_zCP0CRX2uWKf" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_869_z0KRlrCTQKH4"&gt;Basic
and Diluted Loss per Share&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Basic
income/(loss) per common share is computed by dividing net income/(loss) available to common stockholders by the weighted average number
of common shares outstanding during the period. Diluted income/(loss) per common share is computed by dividing net income/(loss) available
to common stockholders by the sum of (1) the weighted-average number of common shares outstanding during the period, (2) the dilutive
effect of the assumed exercise of options and warrants using the treasury stock method and (3) the dilutive effect of other potentially
dilutive securities. For purposes of the diluted net loss per share calculation, options and warrants are potentially dilutive securities
and are excluded from the calculation of diluted net loss per share because their effect would be anti-dilutive.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;As
of September 30, 2023, diluted loss per share excludes &lt;span id="xdx_904_eus-gaap--AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c20221001__20230930_zzmQzTvS2P9b" title="Loss per share for potentially dilutive common shares"&gt;14,271,780&lt;/span&gt; potentially dilutive common shares (2022 &#x2013;&lt;span id="xdx_900_eus-gaap--AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c20211001__20220930_zvFJQdLARASf" title="Loss per share for potentially dilutive common shares"&gt;13,329,616&lt;/span&gt;; 2021 &#x2013;
&lt;span id="xdx_905_eus-gaap--AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c20201001__20210930_zhPkKNvGs2j" title="Loss per share for potentially dilutive common shares"&gt;11,540,903&lt;/span&gt;) related to outstanding options and warrants, as their effect was anti-dilutive.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p id="xdx_84C_eus-gaap--FairValueOfFinancialInstrumentsPolicy_zsg1xhuLguk9" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_861_z1ynJO0M7YLg"&gt;Financial
Instruments&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
book value of the Company&#x2019;s financial instruments, consisting of cash and equivalents, incentive and tax receivables, accounts
payable and accrued liabilities approximate their fair value due to the short-term maturity of such instruments. Unless otherwise noted,
it is management&#x2019;s opinion that the Company is not exposed to significant interest, currency or credit risks arising from these
financial instruments.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p id="xdx_845_eus-gaap--ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_zzpRJBWkzLGg" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_863_zFNDDXLlBLU7"&gt;Foreign
Currency Translation&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
functional currency of the Company is the US dollar. Monetary items denominated in a foreign currency are translated into US dollars
at exchange rates prevailing at the balance sheet date and non-monetary items are translated at exchange rates prevailing when the assets
were acquired, or obligations incurred. Foreign currency denominated expense items are translated at exchange rates prevailing on the
transaction date. Unrealized gains or losses arising from the translations are credited or charged to income in the period in which they
occur.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company has determined that the functional currency of Anavex Australia Pty Limited, Anavex Germany GmbH, and Anavex Canada Ltd. is also
the US dollar.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p id="xdx_847_eus-gaap--SegmentReportingPolicyPolicyTextBlock_zmPlKfcJlDNj" style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_86A_zRFjDP3i0Wx9"&gt;Segment
and Geographic Reporting&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Operating
segments are defined as components of an enterprise for which separate discrete information is available for evaluation by the chief
operating decision maker or decision-making group, in deciding how to allocate resources and in assessing performance. The Company views
its operations and manages its business as one operating segment, which is the business of developing novel therapies for the management
of CNS diseases.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p id="xdx_84C_ecustom--GrantIncomePolicyTextBlock_zRVfCktQIAsj" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_865_z4nGz9Qg9Cfe"&gt;Grant
Income&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Grant
income is recognized at the fair value of the grant when it is received, and all substantive conditions have been satisfied. Grants received
from government and other agencies in advance of the specific research and development costs to which they relate are deferred and recognized
in the consolidated statements of operations in the period they are earned, typically when the related research and development costs
are incurred.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;







&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;/p&gt;








&lt;p id="xdx_840_eus-gaap--IncomeTaxPolicyTextBlock_zZy051LYIQye" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_86B_zFTWQtNxH2pj"&gt;Income
Taxes&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company follows the provisions of ASC 740, which requires the asset and liability method of accounting for income taxes. Under the asset
and liability method, deferred tax assets and liabilities are recognized for the future tax consequences attributable to temporary differences
between the financial statements carrying amounts of existing assets and liabilities and their respective tax bases. Deferred tax assets
and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences
are expected to be recovered or settled.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company follows the provisions of ASC 740 regarding accounting for uncertainty in income taxes. The Company initially recognizes tax
positions in the financial statements when it is more likely than not the position will be sustained upon examination by the tax authorities.
Such tax positions are initially and subsequently measured as the largest amount of tax benefit that is greater than 50% likely of being
realized upon ultimate settlement with the tax authority assuming full knowledge of the position and all relevant facts. Application
requires numerous estimates based on available information. The Company considers many factors when evaluating and estimating its tax
positions and tax benefits, and its recognized tax positions and tax benefits may not accurately anticipate actual outcomes. As additional
information is obtained, there may be a need to periodically adjust the recognized tax positions and tax benefits. These periodic adjustments
may have a material impact on the consolidated statements of operations.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company recognizes interest and penalties related to current income tax expense on the interest income, net line, in the accompanying
consolidated statements of operations. Accrued interest and penalties, if any, are included in accrued liabilities on the consolidated
balance sheets.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p id="xdx_841_eus-gaap--ShareBasedCompensationForfeituresPolicyTextBlock_zTxkzG9e8Qce" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_86C_zro2ToXrby56"&gt;Stock-based
Compensation&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company accounts for all stock-based payments and awards under the fair value method.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
fair value of all share purchase options and warrants are expensed over their contractual vesting period, or over the expected performance
period for only the portion of awards expected to vest, in the case of milestone-based vesting, with a corresponding increase to additional
paid-in capital.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Compensation
costs for stock-based payments with graded vesting are recognized on a straight-line basis. Stock based compensation expense is adjusted
for actual forfeitures of unvested awards as they occur.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company has granted share purchase option awards that vest upon achievement of certain performance criteria, or milestone-based awards.
The Company estimates an implicit service period for achieving performance criteria for each award and recognizes the resulting fair
value as expense over the implicit service period when it concludes that achieving the performance criteria is probable. The Company
periodically reviews and updates as appropriate its estimates of implicit service periods and conclusions on achieving the performance
criteria. Performance awards vest upon achievement of the performance criteria.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company uses the Black-Scholes option valuation model to calculate the fair value of share purchase options and warrants at the date
of the grant. This model requires the input of subjective assumptions, including the expected price volatility and expected life of each&#160;award.
The Company uses the U.S. Treasury daily treasury yield curve rates for the expected term of the option as the risk-free rate. The expected
term represents the period that options granted are expected to be outstanding using the simplified method. The Company&#x2019;s historical
share option exercise experience does not provide sufficient basis for estimating the expected term. Expected volatility is based on
the average of the daily share price changes over the expected term. The Company does not estimate forfeitures and elects to record actual
forfeitures as they occur. The Company has not paid any dividends on its common stock historically, therefore no assumption of dividend
payments is made in the model. These assumptions consist of estimates of future market conditions, which are inherently uncertain, and
therefore, are subject to management&#x2019;s judgment. Changes in these assumptions can materially affect the fair value estimates.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;







&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;/p&gt;








&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
purchase price of options or warrants may be paid in cash or, if approved by the Company&#x2019;s compensation committee (or in the case
of warrants by the Board of Directors) in advance, &#x201c;net settled&#x201d; in shares of the Company&#x2019;s common stock. In a net
settlement of an option or warrant, the Company does not receive payment of the exercise price from the holder but reduces the number
of shares of common stock issued upon the exercise of the stock option or warrant by the smallest number of whole shares that have an
aggregate fair market value equal to or over the aggregate exercise price for the option shares covered by the option or warrant exercised.
Shares issued pursuant to the exercise of options and warrants are issued from the Company&#x2019;s treasury.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p id="xdx_84F_eus-gaap--FairValueMeasurementPolicyPolicyTextBlock_zJIfEwJU8NVi" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_86F_z75dfpAXfjJj"&gt;Fair
Value Measurements&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Fair
value is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal
or most advantageous market for the asset or liability in an orderly transaction between market participants at the measurement date.
Assets and liabilities that are measured at fair value are reported using a three-level fair value hierarchy that prioritizes the inputs
used to measure fair value. This hierarchy maximizes the use of observable inputs and minimizes the use of unobservable inputs. The three
levels of inputs used to measure fair value are as follows:&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Level
1 - 	quoted prices (unadjusted) in active markets for identical assets or liabilities that the Company has the ability to access at
the measurement date;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Level
2 - observable inputs other than Level 1, quoted prices for similar assets or liabilities in active 		markets, quoted prices for
identical or similar assets and liabilities in markets that are not active, and model-derived prices whose inputs are observable or whose
significant value drivers are observable; and&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Level
3 - 	assets and liabilities whose significant value drivers are unobservable by little or no market activity and that are significant
to the fair value of the assets or liabilities.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;At
September 30, 2023 and 2022, the Company did not have any Level 2 or Level 3 assets or liabilities.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p id="xdx_84A_eus-gaap--NewAccountingPronouncementsPolicyPolicyTextBlock_zLldraoEwC7c" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_864_z3SKDNiOVEng"&gt;Recently
Adopted Accounting Pronouncements&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Effective
October 1, 2021, the Company adopted Accounting Standards Update (&#x201c;ASU&#x201d;) 2019-12, &#x201c;Simplifying the Accounting for Income
Taxes (ASC 740)&#x201d;, which is intended to simplify various aspects related to accounting for income taxes by removing certain exceptions
to the general principles in Topic 740 and clarifying and amending existing guidance to improve consistent application. There was no
material impact on the Company&#x2019;s operations, financial condition, or cash flows.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;On
October 1, 2022, the Company adopted ASU 2021-10, Annual Disclosure Requirements for Business Entities Receiving Government Assistance
(Topic 832) &#x2013; Disclosures by Business Entities about Government Assistance, which requires business entities to disclose information
about transactions with a government that are accounted for by applying a grant or contribution model by analogy. For transactions within
scope, the new standard requires the disclosure of information about the nature of the transaction, including significant terms and conditions,
as well as the amounts and specific financial statement line items affected by the transaction. The disclosure of the Company&#x2019;s
research and development tax incentive income and receivable is detailed in Note 4.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;
















</us-gaap:SignificantAccountingPoliciesTextBlock>
    <us-gaap:UseOfEstimates contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_848_eus-gaap--UseOfEstimates_z6qiTKflTLI2" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_86B_zdIdNWMOYl8g"&gt;Use
of Estimates&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
preparation of financial statements in accordance with U.S. GAAP requires management to make estimates and assumptions that affect the
reported amounts of assets and liabilities at the date of the financial statements and the reported amounts of revenue and expenses in
the reporting period. The Company regularly evaluates estimates and assumptions related to accounting for research and development costs,
incentive income receivable, valuation and recoverability of deferred tax assets, stock based compensation, and loss contingencies. The
Company bases its estimates and assumptions on current facts, historical experience, and various other factors that it believes to be
reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and
liabilities and the accrual of costs and expenses that are not readily apparent from other sources. The actual results experienced by
the Company may differ materially and adversely from the Company&#x2019;s estimates. To the extent there are material differences between
the estimates and the actual results, future results of operations will be affected.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;







&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;/p&gt;








</us-gaap:UseOfEstimates>
    <us-gaap:ConsolidationPolicyTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_84A_eus-gaap--ConsolidationPolicyTextBlock_z2ffcVZrWlFa" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_867_zBDDP2KxbUlg"&gt;Principles
of Consolidation&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;These
consolidated financial statements include the accounts of Anavex Life Sciences Corp. and its wholly-owned subsidiaries, Anavex Australia
Pty Limited (&#x201c;Anavex Australia&#x201d;), a company incorporated under the laws of Australia, Anavex Germany GmbH, a company incorporated
under the laws of Germany, and Anavex Canada Ltd., a company incorporated under the laws of the Province of Ontario, Canada. All inter-company
transactions and balances have been eliminated.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</us-gaap:ConsolidationPolicyTextBlock>
    <us-gaap:CashAndCashEquivalentsPolicyTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_842_eus-gaap--CashAndCashEquivalentsPolicyTextBlock_zD2psO58wgqi" style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_860_zXnZYnJ3AxH9"&gt;Cash
and equivalents&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company considers only those investments which are highly liquid, readily convertible to cash and that mature within three months from
the date of purchase to be cash equivalents.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;Highly
liquid investments that are considered cash equivalents include money market&#160;accounts, money market&#160;funds&#160;and&#160;certificates
of deposit. The carrying value of cash equivalents approximates fair value due to the short-term maturity of these securities. The Company&#x2019;s
investment policy allows for investments in domestic money market certificates, certificates of deposit, money market funds, bonds or
commercial papers, and establishes diversification and credit quality requirements and limits investments by maturity and issuer. The
Company currently maintains its investments at one large well known financial institution.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;The
Company maintains its cash in bank deposit accounts which, at times, may exceed federally insured limits. Accounts are guaranteed by
the Federal Deposit Insurance Corporation (FDIC) up to $&lt;span id="xdx_90E_eus-gaap--CashFDICInsuredAmount_iI_c20230930_zOPrmEbs29Na" title="Federal deposit insurance corporation"&gt;250,000&lt;/span&gt; under current regulations. At September 30, 2023 and 2022, substantially
all of the Company&#x2019;s cash balances were in excess of these federally insured limits. The Company mitigates this risk by maintaining
the majority of its cash balances in a large well-known financial institution. The Company has not experienced any losses in such accounts.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</us-gaap:CashAndCashEquivalentsPolicyTextBlock>
    <us-gaap:CashFDICInsuredAmount contextRef="AsOf2023-09-30" decimals="0" unitRef="USD">250000</us-gaap:CashFDICInsuredAmount>
    <us-gaap:ResearchAndDevelopmentExpensePolicy contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_849_eus-gaap--ResearchAndDevelopmentExpensePolicy_znu0D1C47Tij" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_869_zOUCigTgWOAl"&gt;Research
and Development Expenses&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Research
and development costs are expensed as incurred. These expenses are comprised of the costs of the Company&#x2019;s proprietary research
and development efforts, including preclinical studies, clinical trials, manufacturing costs, employee salaries and benefits and stock-based
compensation expense, contract services including external research and development expenses incurred under arrangements with third parties
such as contract research organizations (&#x201c;CROs&#x201d;), facilities costs, overhead costs and other related expenses. Milestone
payments made by the Company to third parties are expensed when the specific milestone has been achieved. Manufacturing costs are expensed
as incurred in accordance with Accounting Standard Codification (&#x201c;ASC&#x201d;) 730, Research and Development, as these materials
have no alternative future use outside of their intended use.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Nonrefundable
advance payments for goods or services that will be used or rendered for future research and development activities are deferred and
amortized over the period that the goods are delivered, or the related services are performed, subject to an assessment of recoverability.
The Company makes estimates of costs incurred in relation to external CROs, and clinical site costs. When evaluating the adequacy of
the accrued liabilities, the Company analyzes progress of the trials and studies including the phase or completion of events, invoices
received and contracted costs. Judgments and estimates are made in determining the accrued balances at the end of any reporting period.
Actual results could differ from the Company&#x2019;s estimates. The Company&#x2019;s historical accrual estimates have not been materially
different from actual costs.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;







&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;/p&gt;








&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;In
addition, the Company incurs expenses in respect of intellectual property costs relating to patents and trademarks. The probability of
success and length of time to develop commercial applications of the drugs subject to the underlying patent and trademark costs is difficult
to determine and numerous risks and uncertainties exist with respect to the timely completion of the development projects. There is no
assurance the drugs subject to the underlying patents and trademarks will ever be successfully commercialized.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Due
to these risks and uncertainties, the patent and trademark costs do not meet the definition of an asset and thus are expensed as incurred
within general and administrative expenses.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</us-gaap:ResearchAndDevelopmentExpensePolicy>
    <us-gaap:RevenueRecognitionIncentives contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_84A_eus-gaap--RevenueRecognitionIncentives_zXLfXylE6t0j" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_86F_zOf8tSfJTM19"&gt;Research
and Development Incentive Income&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company is eligible to obtain certain research and development tax credits, including, through its wholly owned subsidiary Anavex Australia,
the Australian research and development tax incentive credit (the &#x201c;Australia R&amp;amp;D credit&#x201d;) through a program administered
through the Australian Tax Office (the &#x201c;ATO&#x201d;) and AusIndustry, a division of the Australian Government&#x2019;s Department
of Industry, Innovation and Science (&#x201c;AusIndustry&#x201d;). The Australia R&amp;amp;D credit program provides for a cash refund based
on a percentage of eligible research and development activities undertaken in Australia by Anavex Australia. Anavex Australia is also
eligible under the Australia R&amp;amp;D credit program to receive the cash refund for certain research and development expenses incurred
by Anavex Australia outside of Australia, to the extent such expenses are pre-approved by AusIndustry pursuant to an advanced overseas
finding application.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Australia R&amp;amp;D credit program is available to eligible companies with an annual aggregate revenue of less than $20.0 million Australian
during the reimbursable period at a rate of 18.5% above the claimant&#x2019;s company tax rate in Australia.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
tax incentives are available on the basis of specific criteria with which the Company must comply. Although the tax incentive may be
administered through the local tax authority, the Company has accounted for the incentives outside of the scope of ASC Topic 740, Income
Taxes (&#x201c;ASC 740&#x201d;), since the incentives are not linked to the Company&#x2019;s taxable income and can be realized regardless
of whether the Company has generated taxable income in the respective jurisdictions.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;With
respect to the Australia R&amp;amp;D credit, as there is no authoritative guidance under GAAP for accounting for grants to for-profit business
entities, the Company accounts for the grant by analogy to IAS20 Accounting for Government Grants and Disclosure of Government Assistance
(&#x201c;IAS 20&#x201d;). The Company recognizes the Research and Development Incentive income as it incurs costs eligible for reimbursement
under the Australia R&amp;amp;D credit program when it is reasonably assured that the cash incentive will be received, as evidenced through
enrollment in the program and when the applicable conditions under the program have been met. The Company accrues for the amount of cash
refund it expects to receive in relation to research and development expenses outside of Australia only to the extent it has received
advanced approval from AusIndustry, pursuant to an approved advanced overseas finding application.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;In
addition, Anavex Australia and Anavex Canada incur Goods and Services Tax (GST) on certain services provided by local vendors. As a domestic
entity in those jurisdictions, Anavex Australia and Anavex Canada are entitled to a refund of the GST paid. Similarly, Anavex Germany
incurs Value Added Tax (VAT) on certain services provided by local vendors, to which it is entitled to a refund of such VAT paid. The
Company&#x2019;s estimate of the amount of cash refund it expects to receive related to GST and VAT incurred is included in Incentive
and tax receivables in the accompanying consolidated balance sheets.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</us-gaap:RevenueRecognitionIncentives>
    <avxl:LicenseFeesPolicyTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_843_ecustom--LicenseFeesPolicyTextBlock_zbyGkTcneVC" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_867_zUYRjRzpeyi4"&gt;License
Fees&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;The
Company expenses amounts paid to acquire licenses associated with products under development when the ultimate recovery of the amounts
paid is uncertain and the technology has no alternative future use when acquired. Acquisitions of technology licenses are charged to
expense or capitalized based on management&#x2019;s assessment regarding the ultimate recoverability of the amounts paid and the potential
for alternative future use. The Company has determined that the technological feasibility for its product candidates is reached when
the requisite regulatory approvals are obtained to make the product available for sale.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;&#160;&lt;/span&gt;&lt;/p&gt;







&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;/p&gt;








</avxl:LicenseFeesPolicyTextBlock>
    <us-gaap:EarningsPerSharePolicyTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_84A_eus-gaap--EarningsPerSharePolicyTextBlock_zCP0CRX2uWKf" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_869_z0KRlrCTQKH4"&gt;Basic
and Diluted Loss per Share&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Basic
income/(loss) per common share is computed by dividing net income/(loss) available to common stockholders by the weighted average number
of common shares outstanding during the period. Diluted income/(loss) per common share is computed by dividing net income/(loss) available
to common stockholders by the sum of (1) the weighted-average number of common shares outstanding during the period, (2) the dilutive
effect of the assumed exercise of options and warrants using the treasury stock method and (3) the dilutive effect of other potentially
dilutive securities. For purposes of the diluted net loss per share calculation, options and warrants are potentially dilutive securities
and are excluded from the calculation of diluted net loss per share because their effect would be anti-dilutive.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;As
of September 30, 2023, diluted loss per share excludes &lt;span id="xdx_904_eus-gaap--AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c20221001__20230930_zzmQzTvS2P9b" title="Loss per share for potentially dilutive common shares"&gt;14,271,780&lt;/span&gt; potentially dilutive common shares (2022 &#x2013;&lt;span id="xdx_900_eus-gaap--AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c20211001__20220930_zvFJQdLARASf" title="Loss per share for potentially dilutive common shares"&gt;13,329,616&lt;/span&gt;; 2021 &#x2013;
&lt;span id="xdx_905_eus-gaap--AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_c20201001__20210930_zhPkKNvGs2j" title="Loss per share for potentially dilutive common shares"&gt;11,540,903&lt;/span&gt;) related to outstanding options and warrants, as their effect was anti-dilutive.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</us-gaap:EarningsPerSharePolicyTextBlock>
    <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
      contextRef="From2022-10-01to2023-09-30"
      decimals="INF"
      unitRef="Shares">14271780</us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount>
    <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
      contextRef="From2021-10-012022-09-30"
      decimals="INF"
      unitRef="Shares">13329616</us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount>
    <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
      contextRef="From2020-10-012021-09-30"
      decimals="INF"
      unitRef="Shares">11540903</us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount>
    <us-gaap:FairValueOfFinancialInstrumentsPolicy contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_84C_eus-gaap--FairValueOfFinancialInstrumentsPolicy_zsg1xhuLguk9" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_861_z1ynJO0M7YLg"&gt;Financial
Instruments&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
book value of the Company&#x2019;s financial instruments, consisting of cash and equivalents, incentive and tax receivables, accounts
payable and accrued liabilities approximate their fair value due to the short-term maturity of such instruments. Unless otherwise noted,
it is management&#x2019;s opinion that the Company is not exposed to significant interest, currency or credit risks arising from these
financial instruments.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</us-gaap:FairValueOfFinancialInstrumentsPolicy>
    <us-gaap:ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_845_eus-gaap--ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_zzpRJBWkzLGg" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_863_zFNDDXLlBLU7"&gt;Foreign
Currency Translation&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
functional currency of the Company is the US dollar. Monetary items denominated in a foreign currency are translated into US dollars
at exchange rates prevailing at the balance sheet date and non-monetary items are translated at exchange rates prevailing when the assets
were acquired, or obligations incurred. Foreign currency denominated expense items are translated at exchange rates prevailing on the
transaction date. Unrealized gains or losses arising from the translations are credited or charged to income in the period in which they
occur.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company has determined that the functional currency of Anavex Australia Pty Limited, Anavex Germany GmbH, and Anavex Canada Ltd. is also
the US dollar.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</us-gaap:ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock>
    <us-gaap:SegmentReportingPolicyPolicyTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_847_eus-gaap--SegmentReportingPolicyPolicyTextBlock_zmPlKfcJlDNj" style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_86A_zRFjDP3i0Wx9"&gt;Segment
and Geographic Reporting&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Operating
segments are defined as components of an enterprise for which separate discrete information is available for evaluation by the chief
operating decision maker or decision-making group, in deciding how to allocate resources and in assessing performance. The Company views
its operations and manages its business as one operating segment, which is the business of developing novel therapies for the management
of CNS diseases.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</us-gaap:SegmentReportingPolicyPolicyTextBlock>
    <avxl:GrantIncomePolicyTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_84C_ecustom--GrantIncomePolicyTextBlock_zRVfCktQIAsj" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_865_z4nGz9Qg9Cfe"&gt;Grant
Income&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Grant
income is recognized at the fair value of the grant when it is received, and all substantive conditions have been satisfied. Grants received
from government and other agencies in advance of the specific research and development costs to which they relate are deferred and recognized
in the consolidated statements of operations in the period they are earned, typically when the related research and development costs
are incurred.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;







&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;/p&gt;








</avxl:GrantIncomePolicyTextBlock>
    <us-gaap:IncomeTaxPolicyTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_840_eus-gaap--IncomeTaxPolicyTextBlock_zZy051LYIQye" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_86B_zFTWQtNxH2pj"&gt;Income
Taxes&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company follows the provisions of ASC 740, which requires the asset and liability method of accounting for income taxes. Under the asset
and liability method, deferred tax assets and liabilities are recognized for the future tax consequences attributable to temporary differences
between the financial statements carrying amounts of existing assets and liabilities and their respective tax bases. Deferred tax assets
and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences
are expected to be recovered or settled.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company follows the provisions of ASC 740 regarding accounting for uncertainty in income taxes. The Company initially recognizes tax
positions in the financial statements when it is more likely than not the position will be sustained upon examination by the tax authorities.
Such tax positions are initially and subsequently measured as the largest amount of tax benefit that is greater than 50% likely of being
realized upon ultimate settlement with the tax authority assuming full knowledge of the position and all relevant facts. Application
requires numerous estimates based on available information. The Company considers many factors when evaluating and estimating its tax
positions and tax benefits, and its recognized tax positions and tax benefits may not accurately anticipate actual outcomes. As additional
information is obtained, there may be a need to periodically adjust the recognized tax positions and tax benefits. These periodic adjustments
may have a material impact on the consolidated statements of operations.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company recognizes interest and penalties related to current income tax expense on the interest income, net line, in the accompanying
consolidated statements of operations. Accrued interest and penalties, if any, are included in accrued liabilities on the consolidated
balance sheets.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</us-gaap:IncomeTaxPolicyTextBlock>
    <us-gaap:ShareBasedCompensationForfeituresPolicyTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_841_eus-gaap--ShareBasedCompensationForfeituresPolicyTextBlock_zTxkzG9e8Qce" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_86C_zro2ToXrby56"&gt;Stock-based
Compensation&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company accounts for all stock-based payments and awards under the fair value method.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
fair value of all share purchase options and warrants are expensed over their contractual vesting period, or over the expected performance
period for only the portion of awards expected to vest, in the case of milestone-based vesting, with a corresponding increase to additional
paid-in capital.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Compensation
costs for stock-based payments with graded vesting are recognized on a straight-line basis. Stock based compensation expense is adjusted
for actual forfeitures of unvested awards as they occur.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company has granted share purchase option awards that vest upon achievement of certain performance criteria, or milestone-based awards.
The Company estimates an implicit service period for achieving performance criteria for each award and recognizes the resulting fair
value as expense over the implicit service period when it concludes that achieving the performance criteria is probable. The Company
periodically reviews and updates as appropriate its estimates of implicit service periods and conclusions on achieving the performance
criteria. Performance awards vest upon achievement of the performance criteria.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company uses the Black-Scholes option valuation model to calculate the fair value of share purchase options and warrants at the date
of the grant. This model requires the input of subjective assumptions, including the expected price volatility and expected life of each&#160;award.
The Company uses the U.S. Treasury daily treasury yield curve rates for the expected term of the option as the risk-free rate. The expected
term represents the period that options granted are expected to be outstanding using the simplified method. The Company&#x2019;s historical
share option exercise experience does not provide sufficient basis for estimating the expected term. Expected volatility is based on
the average of the daily share price changes over the expected term. The Company does not estimate forfeitures and elects to record actual
forfeitures as they occur. The Company has not paid any dividends on its common stock historically, therefore no assumption of dividend
payments is made in the model. These assumptions consist of estimates of future market conditions, which are inherently uncertain, and
therefore, are subject to management&#x2019;s judgment. Changes in these assumptions can materially affect the fair value estimates.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;







&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;/p&gt;








&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
purchase price of options or warrants may be paid in cash or, if approved by the Company&#x2019;s compensation committee (or in the case
of warrants by the Board of Directors) in advance, &#x201c;net settled&#x201d; in shares of the Company&#x2019;s common stock. In a net
settlement of an option or warrant, the Company does not receive payment of the exercise price from the holder but reduces the number
of shares of common stock issued upon the exercise of the stock option or warrant by the smallest number of whole shares that have an
aggregate fair market value equal to or over the aggregate exercise price for the option shares covered by the option or warrant exercised.
Shares issued pursuant to the exercise of options and warrants are issued from the Company&#x2019;s treasury.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</us-gaap:ShareBasedCompensationForfeituresPolicyTextBlock>
    <us-gaap:FairValueMeasurementPolicyPolicyTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_84F_eus-gaap--FairValueMeasurementPolicyPolicyTextBlock_zJIfEwJU8NVi" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_86F_z75dfpAXfjJj"&gt;Fair
Value Measurements&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Fair
value is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal
or most advantageous market for the asset or liability in an orderly transaction between market participants at the measurement date.
Assets and liabilities that are measured at fair value are reported using a three-level fair value hierarchy that prioritizes the inputs
used to measure fair value. This hierarchy maximizes the use of observable inputs and minimizes the use of unobservable inputs. The three
levels of inputs used to measure fair value are as follows:&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Level
1 - 	quoted prices (unadjusted) in active markets for identical assets or liabilities that the Company has the ability to access at
the measurement date;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Level
2 - observable inputs other than Level 1, quoted prices for similar assets or liabilities in active 		markets, quoted prices for
identical or similar assets and liabilities in markets that are not active, and model-derived prices whose inputs are observable or whose
significant value drivers are observable; and&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Level
3 - 	assets and liabilities whose significant value drivers are unobservable by little or no market activity and that are significant
to the fair value of the assets or liabilities.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;At
September 30, 2023 and 2022, the Company did not have any Level 2 or Level 3 assets or liabilities.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</us-gaap:FairValueMeasurementPolicyPolicyTextBlock>
    <us-gaap:NewAccountingPronouncementsPolicyPolicyTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_84A_eus-gaap--NewAccountingPronouncementsPolicyPolicyTextBlock_zLldraoEwC7c" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&lt;span id="xdx_864_z3SKDNiOVEng"&gt;Recently
Adopted Accounting Pronouncements&lt;/span&gt;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Effective
October 1, 2021, the Company adopted Accounting Standards Update (&#x201c;ASU&#x201d;) 2019-12, &#x201c;Simplifying the Accounting for Income
Taxes (ASC 740)&#x201d;, which is intended to simplify various aspects related to accounting for income taxes by removing certain exceptions
to the general principles in Topic 740 and clarifying and amending existing guidance to improve consistent application. There was no
material impact on the Company&#x2019;s operations, financial condition, or cash flows.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;On
October 1, 2022, the Company adopted ASU 2021-10, Annual Disclosure Requirements for Business Entities Receiving Government Assistance
(Topic 832) &#x2013; Disclosures by Business Entities about Government Assistance, which requires business entities to disclose information
about transactions with a government that are accounted for by applying a grant or contribution model by analogy. For transactions within
scope, the new standard requires the disclosure of information about the nature of the transaction, including significant terms and conditions,
as well as the amounts and specific financial statement line items affected by the transaction. The disclosure of the Company&#x2019;s
research and development tax incentive income and receivable is detailed in Note 4.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;
















</us-gaap:NewAccountingPronouncementsPolicyPolicyTextBlock>
    <avxl:AccuredLiabilitiesTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_800_ecustom--AccuredLiabilitiesTextBlock_zWiWbayK1Fog" style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;Note
3	&lt;span id="xdx_82E_zhZbrFyFkNS2"&gt;Accrued Liabilities&lt;/span&gt; &lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
principal components of accrued liabilities consist of (in thousands):&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;/span&gt;&lt;/p&gt;

&lt;table cellpadding="0" cellspacing="0" id="xdx_88F_eus-gaap--ScheduleOfAccruedLiabilitiesTableTextBlock_pn3n3_zw7Q0sR5wox1" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Accrued Liabilities (Details)"&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span id="xdx_8B9_z9D2IZIcaaxc" style="display: none"&gt;Schedule of principal components of accrued liabilities&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td id="xdx_49F_20230930_zOblcHItXB76" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td id="xdx_496_20220930_zC7voMSPrPQc" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="7" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;September
30,&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2022&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40F_ecustom--AccruedClinicalSiteAndPatientVisitsCosts_iI_maALCz5rZ_zzgKyxye7SBb" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; width: 56%; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Accrued
clinical site and patient visits costs&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 8%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 12%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,006&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 8%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 12%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,031&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_403_eus-gaap--AccruedBonusesCurrent_iI_maALCz5rZ_zPPgeMs8YLF3" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Accrued
compensation and benefits&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,360&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,298&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40A_ecustom--FixedContractAccruals_iI_maALCz5rZ_zGGMM1w3vkW4" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Fixed
contract accruals&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;38&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;417&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_405_ecustom--MilestoneBasedContractAccruals_iI_maALCz5rZ_zewnh5C4LrUk" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Milestone
based contract accruals&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,267&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;137&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40B_eus-gaap--OtherAccruedLiabilitiesCurrent_iI_maALCz5rZ_z65jJeLLNDBi" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;All
other accrued liabilities&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,624&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,062&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_400_eus-gaap--AccruedLiabilitiesCurrent_iTI_mtALCz5rZ_zK68g3Y0HK82" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 2.5pt 10pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Total
accrued liabilities&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;7,295&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5,945&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;



&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</avxl:AccuredLiabilitiesTextBlock>
    <us-gaap:ScheduleOfAccruedLiabilitiesTableTextBlock contextRef="From2022-10-01to2023-09-30">&lt;table cellpadding="0" cellspacing="0" id="xdx_88F_eus-gaap--ScheduleOfAccruedLiabilitiesTableTextBlock_pn3n3_zw7Q0sR5wox1" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Accrued Liabilities (Details)"&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span id="xdx_8B9_z9D2IZIcaaxc" style="display: none"&gt;Schedule of principal components of accrued liabilities&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td id="xdx_49F_20230930_zOblcHItXB76" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td id="xdx_496_20220930_zC7voMSPrPQc" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="7" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;September
30,&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2022&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40F_ecustom--AccruedClinicalSiteAndPatientVisitsCosts_iI_maALCz5rZ_zzgKyxye7SBb" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; width: 56%; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Accrued
clinical site and patient visits costs&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 8%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 12%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,006&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 8%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 12%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,031&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_403_eus-gaap--AccruedBonusesCurrent_iI_maALCz5rZ_zPPgeMs8YLF3" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Accrued
compensation and benefits&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,360&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,298&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40A_ecustom--FixedContractAccruals_iI_maALCz5rZ_zGGMM1w3vkW4" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Fixed
contract accruals&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;38&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;417&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_405_ecustom--MilestoneBasedContractAccruals_iI_maALCz5rZ_zewnh5C4LrUk" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Milestone
based contract accruals&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,267&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;137&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40B_eus-gaap--OtherAccruedLiabilitiesCurrent_iI_maALCz5rZ_z65jJeLLNDBi" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;All
other accrued liabilities&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,624&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,062&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_400_eus-gaap--AccruedLiabilitiesCurrent_iTI_mtALCz5rZ_zK68g3Y0HK82" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 2.5pt 10pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Total
accrued liabilities&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;7,295&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5,945&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</us-gaap:ScheduleOfAccruedLiabilitiesTableTextBlock>
    <avxl:AccruedClinicalSiteAndPatientVisitsCosts contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">2006000</avxl:AccruedClinicalSiteAndPatientVisitsCosts>
    <avxl:AccruedClinicalSiteAndPatientVisitsCosts contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">2031000</avxl:AccruedClinicalSiteAndPatientVisitsCosts>
    <us-gaap:AccruedBonusesCurrent contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">1360000</us-gaap:AccruedBonusesCurrent>
    <us-gaap:AccruedBonusesCurrent contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">1298000</us-gaap:AccruedBonusesCurrent>
    <avxl:FixedContractAccruals contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">38000</avxl:FixedContractAccruals>
    <avxl:FixedContractAccruals contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">417000</avxl:FixedContractAccruals>
    <avxl:MilestoneBasedContractAccruals contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">1267000</avxl:MilestoneBasedContractAccruals>
    <avxl:MilestoneBasedContractAccruals contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">137000</avxl:MilestoneBasedContractAccruals>
    <us-gaap:OtherAccruedLiabilitiesCurrent contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">2624000</us-gaap:OtherAccruedLiabilitiesCurrent>
    <us-gaap:OtherAccruedLiabilitiesCurrent contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">2062000</us-gaap:OtherAccruedLiabilitiesCurrent>
    <us-gaap:AccruedLiabilitiesCurrent contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">7295000</us-gaap:AccruedLiabilitiesCurrent>
    <us-gaap:AccruedLiabilitiesCurrent contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">5945000</us-gaap:AccruedLiabilitiesCurrent>
    <avxl:OtherIncomeDisclosureTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_804_ecustom--OtherIncomeDisclosureTextBlock_z7ED0CC1PYJ4" style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;Note
4	&lt;span id="xdx_820_zezQfDrLEqdi"&gt;Other Income&lt;/span&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;Grant
income&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;During
the year ended September 30, 2023, the Company received $&lt;span id="xdx_906_ecustom--GrantIncome_pn5n6_c20221001__20230930_zIuHWYwmVaId" title="Grant income"&gt;0.5&lt;/span&gt; million (2022: $&lt;span id="xdx_903_ecustom--GrantIncome_c20211001__20220930_zd1fw8vKH0Bj" title="Grant income"&gt;0&lt;/span&gt; 2021: $&lt;span id="xdx_905_ecustom--GrantIncome_pn5n6_c20201001__20210930_zKaZ0kl3IiR7" title="Grant income"&gt;0.5&lt;/span&gt; million) of a $&lt;span id="xdx_903_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20201001__20210930__us-gaap--RelatedPartyTransactionsByRelatedPartyAxis__custom--MichaelJFoxFoundationMember_zUiITfrFOqaa" title="Research and development incentive income"&gt;1&lt;/span&gt;.0 million research grant awarded
during the year ended September 30, 2021, by the Michael J. Fox Foundation for Parkinson&#x2019;s Research. The grant will be used to
fund a clinical trial of the Company&#x2019;s lead compound, ANAVEX&lt;sup&gt;&#xae;&lt;/sup&gt;2-73 (blarcamesine) related to Parkinson&#x2019;s disease.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
grant income was deferred when received and amortized to other income as the related research and development expenditures are incurred.
During the year ended September 30, 2023, the Company recognized $&lt;span id="xdx_90D_ecustom--NonOperatingIncomeFromGrant_c20221001__20230930_zlOdEtzkeJL3" title="Non operating income from grant"&gt;25,000&lt;/span&gt; (2022: $&lt;span id="xdx_903_ecustom--NonOperatingIncomeFromGrant_c20211001__20220930_zkvjDz7v4wHd" title="Non operating income from grant"&gt;0&lt;/span&gt;; 2021: $&lt;span id="xdx_900_ecustom--NonOperatingIncomeFromGrant_c20201001__20210930_z2o8qeI1rZo4" title="Non operating income from grant"&gt;54,100&lt;/span&gt;) of this grant on its statements of
operations within grant income. At September 30, 2023 an amount of $&lt;span id="xdx_906_ecustom--DeferredGrantIncome1_pn5n6_c20221001__20230930_zxwtGse5Gk57" title="Deferred grant income"&gt;0.9&lt;/span&gt; million (2022: $&lt;span id="xdx_90B_ecustom--DeferredGrantIncome1_pn5n6_c20211001__20220930_ztxPyoxVQksl" title="Deferred grant income"&gt;0.4&lt;/span&gt; million) of this grant is recorded as deferred
grant income, representing the amount of this grant which has not yet been amortized to other income. The Company will recognize this
income on its statements of operations as the related expenditures are incurred to offset the income.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;Research
and development incentive income&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Research
and development incentive income represents the income earned by Anavex Australia of the Australia R&amp;amp;D credit. This cash incentive
is received by Anavex Australia, upon filing of a claim in connection with Anavex Australia&#x2019;s annual income tax return.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;During
the year ended September 30, 2023, the Company recorded research and development incentive income of $&lt;span id="xdx_900_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20221001__20230930_zID3NUwQhl64" title="Research and development incentive income"&gt;2.7&lt;/span&gt; million (AUD &lt;span id="xdx_906_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20221001__20230930__srt--CurrencyAxis__currency--AUD_zU8tfJYJcOWc" title="Research and development incentive income"&gt;4.1&lt;/span&gt; million) (2022:
$&lt;span id="xdx_900_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20211001__20220930_z9qs1g3PLpXc" title="Research and development incentive income"&gt;3.3&lt;/span&gt; million (AUD &lt;span id="xdx_908_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20211001__20220930__srt--CurrencyAxis__currency--AUD_zXzB35mMhmpl" title="Research and development incentive income"&gt;4.5&lt;/span&gt; million); 2021: $&lt;span id="xdx_90B_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20201001__20210930_zl46LELTKP84" title="Research and development incentive income"&gt;4.5&lt;/span&gt; million (AUD &lt;span id="xdx_90F_eus-gaap--ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned_pn5n6_c20201001__20210930__srt--CurrencyAxis__currency--AUD_zJ25LJXGoyc5" title="Research and development incentive income"&gt;6.1&lt;/span&gt; million)) in respect of the Australia R&amp;amp;D credit for eligible research
and development expenses incurred during the year. This amount is included within Other income (expense) on the consolidated statements
of operations.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;At
September 30, 2023, Incentive and tax receivables includes $&lt;span id="xdx_904_eus-gaap--OtherReceivables_iI_pn5n6_c20230930_zzdtGDxecS6i" title="Incentive and tax receivables"&gt;2.5&lt;/span&gt; million (AUD &lt;span id="xdx_903_eus-gaap--OtherReceivables_iI_pn5n6_c20230930__srt--CurrencyAxis__currency--AUD_z33if1GWYJ43" title="Incentive and tax receivables"&gt;3.9&lt;/span&gt; million) (2022: $&lt;span id="xdx_906_eus-gaap--OtherReceivables_iI_pn5n6_c20220930_zl6nET4zhSgf" title="Incentive and tax receivables"&gt;2.9&lt;/span&gt; million (AUD &lt;span id="xdx_908_eus-gaap--OtherReceivables_iI_pn5n6_c20220930__srt--CurrencyAxis__currency--AUD_z4Fmw8vKgvI2" title="Incentive and tax receivables"&gt;4.5&lt;/span&gt; million) relating
to Australia R&amp;amp;D credits earned during the year that are expected to be reimbursed upon filing of the Company&#x2019;s annual claim
under this program.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Australia R&amp;amp;D credit program is a self-assess program whereby the Company must assess its eligibility each year to determine (i)
if the entity is eligible (ii) if the specific R&amp;amp;D activities are eligible and (iii) if the individual R&amp;amp;D expenditures have
nexus to such R&amp;amp;D activities. The Company evaluates its eligibility under the tax incentive program as of each balance sheet date
based on the most current and relevant data available. Anavex Australia is able to continue to claim the R&amp;amp;D tax incentive for as
long as it remains eligible and continues to incur eligible research and development expenditures.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;







&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;/p&gt;








&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Although
the Company believes that it has complied with all the relevant conditions of eligibility under the program for all periods claimed,
the ATO has the right to review the Company&#x2019;s qualifying programs and related expenditures for a period of four years. If such
a review were to occur, the ATO may have different interpretations of certain eligibility requirements. If the ATO disagreed with the
Company&#x2019;s assessments and any related subsequent appeals, it could require adjustment to and repayment of current or previous years&#x2019;
claims already received. Additionally, if the Company was unable to demonstrate a reasonably arguable position taken on such claims,
the ATO could also assess penalties and interest on such adjustment.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Currently,
the Company&#x2019;s tax incentive claims from 2019 to 2022 are open to potential review by the ATO. Additionally, the period open for
review is indefinite if the ATO suspects fraud. The Company has not provided any allowance for any such potential adjustments, should
they occur in the future.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</avxl:OtherIncomeDisclosureTextBlock>
    <avxl:GrantIncome
      contextRef="From2022-10-01to2023-09-30"
      decimals="-5"
      unitRef="USD">500000</avxl:GrantIncome>
    <avxl:GrantIncome
      contextRef="From2021-10-012022-09-30"
      decimals="0"
      unitRef="USD">0</avxl:GrantIncome>
    <avxl:GrantIncome
      contextRef="From2020-10-012021-09-30"
      decimals="-5"
      unitRef="USD">500000</avxl:GrantIncome>
    <us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned
      contextRef="From2020-10-012021-09-30_custom_MichaelJFoxFoundationMember"
      decimals="-5"
      unitRef="USD">1000000</us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned>
    <avxl:NonOperatingIncomeFromGrant
      contextRef="From2022-10-01to2023-09-30"
      decimals="0"
      unitRef="USD">25000</avxl:NonOperatingIncomeFromGrant>
    <avxl:NonOperatingIncomeFromGrant
      contextRef="From2021-10-012022-09-30"
      decimals="0"
      unitRef="USD">0</avxl:NonOperatingIncomeFromGrant>
    <avxl:NonOperatingIncomeFromGrant
      contextRef="From2020-10-012021-09-30"
      decimals="0"
      unitRef="USD">54100</avxl:NonOperatingIncomeFromGrant>
    <avxl:DeferredGrantIncome1
      contextRef="From2022-10-01to2023-09-30"
      decimals="-5"
      unitRef="USD">900000</avxl:DeferredGrantIncome1>
    <avxl:DeferredGrantIncome1
      contextRef="From2021-10-012022-09-30"
      decimals="-5"
      unitRef="USD">400000</avxl:DeferredGrantIncome1>
    <us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned
      contextRef="From2022-10-01to2023-09-30"
      decimals="-5"
      unitRef="USD">2700000</us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned>
    <us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned
      contextRef="From2022-10-012023-09-30_currency_AUD"
      decimals="-5"
      unitRef="USD">4100000</us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned>
    <us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned
      contextRef="From2021-10-012022-09-30"
      decimals="-5"
      unitRef="USD">3300000</us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned>
    <us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned
      contextRef="From2021-10-012022-09-30_currency_AUD"
      decimals="-5"
      unitRef="USD">4500000</us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned>
    <us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned
      contextRef="From2020-10-012021-09-30"
      decimals="-5"
      unitRef="USD">4500000</us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned>
    <us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned
      contextRef="From2020-10-012021-09-30_currency_AUD"
      decimals="-5"
      unitRef="USD">6100000</us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned>
    <us-gaap:OtherReceivables contextRef="AsOf2023-09-30" decimals="-5" unitRef="USD">2500000</us-gaap:OtherReceivables>
    <us-gaap:OtherReceivables
      contextRef="AsOf2023-09-30_currency_AUD"
      decimals="-5"
      unitRef="USD">3900000</us-gaap:OtherReceivables>
    <us-gaap:OtherReceivables contextRef="AsOf2022-09-30" decimals="-5" unitRef="USD">2900000</us-gaap:OtherReceivables>
    <us-gaap:OtherReceivables
      contextRef="AsOf2022-09-30_currency_AUD"
      decimals="-5"
      unitRef="USD">4500000</us-gaap:OtherReceivables>
    <avxl:EquityOfferingTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_804_ecustom--EquityOfferingTextBlock_zb4TDoN2phd4" style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;Note
5	&lt;span id="xdx_820_zyNNCA0EwmA4"&gt;Equity Offerings&lt;/span&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;Common
Stock&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Common
shares are voting and are entitled to dividends as declared at the discretion of the Board of Directors.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;Preferred
Stock&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company&#x2019;s Board of Directors&#160;(the &#x201c;Board&#x201d;)&#160;has the authority to issue preferred stock in one or more series
and to fix the rights, preferences, privileges, restrictions and the number of shares constituting any series or the designation of the
series.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;Registered
Direct Offering&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;On
June 22, 2021, the Company and Deep Track Capital entered into a securities purchase agreement pursuant to which the Company sold to
Deep Track Capital an aggregate of &lt;span id="xdx_90D_eus-gaap--SaleOfStockNumberOfSharesIssuedInTransaction_pip0_c20210621__20210622__us-gaap--TypeOfArrangementAxis__custom--SecuritiesPurchaseAgreementMember_zc6y134LHS88" title="Sale of stock, shares"&gt;2,380,953&lt;/span&gt; shares of common stock at $&lt;span id="xdx_902_eus-gaap--SaleOfStockPricePerShare_iI_pip0_c20210622__us-gaap--TypeOfArrangementAxis__custom--SecuritiesPurchaseAgreementMember_zW7JGKcfhi15" title="Sale of stock, per share"&gt;21&lt;/span&gt; per share in a registered direct offering, for gross proceeds
of $&lt;span id="xdx_909_eus-gaap--SaleOfStockConsiderationReceivedOnTransaction_pn6n6_c20210621__20210622__us-gaap--TypeOfArrangementAxis__custom--SecuritiesPurchaseAgreementMember_zpiUI66Lxw1a" title="Gross proceeds from sale of stock"&gt;50&lt;/span&gt; million. Net proceeds of the offering were $&lt;span id="xdx_90E_eus-gaap--ProceedsFromIssuanceInitialPublicOffering_c20210621__20210622__us-gaap--TypeOfArrangementAxis__custom--SecuritiesPurchaseAgreementMember_zUSWYrXZ3X09" title="Proceed from offering"&gt;46,902,981&lt;/span&gt; after deducting offering fees and expenses.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;Sales
Agreement&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company entered into a Controlled Equity Offering Sales Agreement on July 6, 2018, which was amended and restated on May 1, 2020 (the
&#x201c;Sales Agreement&#x201d;) with Cantor Fitzgerald&#160;&amp;amp; Co. and SVB Leerink LLC (together the &#x201c;Sales Agents&#x201d;), pursuant
to which the Company may offer and sell shares of common stock registered under an effective registration statement from time to time
through the Sales Agents (the &#x201c;Offering&#x201d;).&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Upon
delivery of a placement notice based on the Company&#x2019;s instructions and subject to the terms and conditions of the Sales Agreement,
the Sales Agents may sell the Shares by methods deemed to be an &#x201c;at the market offering&#x201d; offering, in negotiated transactions
at market prices prevailing at the time of sale or at prices related to such prevailing market prices, or by any other method permitted
by law, including negotiated transactions, subject to the prior written consent of the Company. The Company is not obligated to make
any sales of Shares under the Sales Agreement. The Company or Sales Agents may suspend or terminate the offering of Shares upon notice
to the other party, subject to certain conditions. The Sales Agents will act as agent on a commercially reasonable efforts basis consistent
with their normal trading and sales practices and applicable state and federal law, rules&#160;and regulations and the rules&#160;of
Nasdaq.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company has agreed to pay the Sales Agents commissions for their services of up to &lt;span id="xdx_903_ecustom--PercentageOfGrossProceedsFromSales_pip0_dp_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zlabhXU0ZUv5" title="Percentage of gross proceeds from sales"&gt;3.0&lt;/span&gt;% of the gross proceeds from the sale of the Shares
pursuant to the Sales Agreement. The Company also agreed to provide the Sales Agents with customary indemnification and contribution
rights. During the year ended September 30, 2023, &lt;span id="xdx_90A_eus-gaap--SaleOfStockNumberOfSharesIssuedInTransaction_pip0_do_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zQ3IqyGRUkTa" title="Number of common stock sold, shares"&gt;no&lt;/span&gt; shares were sold pursuant to the Offering. During the year ended September 30, 2022,
&lt;span id="xdx_906_eus-gaap--SaleOfStockNumberOfSharesIssuedInTransaction_pip0_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zjhhMExQvuvh" title="Number of common stock sold, shares"&gt;1,623,813&lt;/span&gt; shares were sold pursuant to the Offering for gross proceeds of $&lt;span id="xdx_900_eus-gaap--SaleOfStockConsiderationReceivedPerTransaction_pn6n6_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zW5D1KhaZJV1" title="Number of common stock sold, value"&gt;21&lt;/span&gt;.0 million (net proceeds of $&lt;span id="xdx_90A_eus-gaap--ProceedsFromIssuanceInitialPublicOffering_pn5n6_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zPbB3LyZ0Sqi" title="Net proceed"&gt;20.3&lt;/span&gt; million after deducting
offering expenses) (2021: &lt;span id="xdx_908_eus-gaap--SaleOfStockNumberOfSharesIssuedInTransaction_pip0_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zMmT4jfnutZ5" title="Number of common stock sold"&gt;5,634,576&lt;/span&gt; shares were sold for gross proceeds of $&lt;span id="xdx_90C_ecustom--SoldForGrossProceedsAmount_pn5n6_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zBr3s8zoCXxc" title="Sold for gross proceeds amount"&gt;79.1&lt;/span&gt; million, net proceeds of $&lt;span id="xdx_90E_eus-gaap--ProceedsFromIssuanceInitialPublicOffering_pn5n6_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--EquityOfferingSalesAgreementMember_zI1CybzBzu9d" title="Net proceed"&gt;76.7&lt;/span&gt; million). At September
30, 2023, an amount of $&lt;span id="xdx_90F_ecustom--SalesOfAgreementAmount_iI_pn5n6_c20230930_zosJik8ijhB" title="Sales of agreement amount"&gt;142.4&lt;/span&gt; million (2022: $&lt;span id="xdx_907_ecustom--SalesOfAgreementAmount_iI_pn5n6_c20220930_zHv3V2kjN8Xe" title="Sales of agreement amount"&gt;142.4&lt;/span&gt; million) was registered pursuant to an effective registration statement. The Company
currently does not have access to sell shares of common stock under the Sales Agreement.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;







&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;/p&gt;








&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;2023
Purchase Agreement&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;On
February 3, 2023, the Company entered into a $150.0 million purchase agreement (the &#x201c;2023 Purchase Agreement&#x201d;) with Lincoln
Park Capital Fund, LLC (&#x201c;Lincoln Park&#x201d;), pursuant to which the Company has the right to sell and issue to Lincoln Park, and
Lincoln Park is obligated to purchase, up to $&lt;span id="xdx_90F_ecustom--ValueOfSharesObligatedToPurchase_pn6n6_c20230202__20230203__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zcxkDCBcwoBl" title="Value of shares obligated to purchase"&gt;150&lt;/span&gt;.0 million in value of its shares of common stock from time to time over a three-year
period until February 3, 2026.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;In
consideration for entering into the 2023 Purchase Agreement, the Company issued to Lincoln Park &lt;span id="xdx_909_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20230202__20230203__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_z8aVciu8dKa4" title="Share issued for offering, shares"&gt;75,000&lt;/span&gt; shares of common stock as a commitment
fee (the &#x201c;initial commitment shares&#x201d;) and agreed to issue up to an additional &lt;span id="xdx_905_ecustom--NumberOfSharesObligatedToPurchaseProrataBasic_pip0_c20230202__20230203__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zDmvYDmRpIR4" title="Pro rata basic number of shares obligated to purchase"&gt;75,000&lt;/span&gt; shares pro rata, when and if, Lincoln
Park purchased, at the Company&#x2019;s discretion, the $&lt;span id="xdx_904_eus-gaap--ProceedsFromIssuanceOrSaleOfEquity_pn6n6_c20230202__20230203__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zWtvzgAbQT47" title="Proceeds from issuance or sale of equity"&gt;150&lt;/span&gt;.0 million aggregate commitment. The Company determined the fair value of
the initial commitment shares was $&lt;span id="xdx_90C_ecustom--FairValueOfInitialCommitment_iI_pn5n6_c20230930_z4HQFCRySBs8" title="Fair value of the initial commitment"&gt;0.8&lt;/span&gt; million with reference to the closing price of the Company&#x2019;s shares on the Purchase Agreement
date. In addition, the Company incurred third party expenses of $&lt;span id="xdx_900_ecustom--IncurredExpenses_iI_pn5n6_c20230930_zqBMreamcBK4" title="Incurred expenses"&gt;0.1&lt;/span&gt; million in connection with entering into the Purchase Agreement.
These amounts were expensed to other financing expense on the statements of operations during the year ended September 30, 2023.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;During
the year ended September 30, 2023, the Company issued to Lincoln Park an aggregate of &lt;span id="xdx_906_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockIncludingCommitmentSharesMember_zjTYlplPSAh2" title="Number of shares issued, shares"&gt;3,288,943&lt;/span&gt; (2022: &lt;span id="xdx_907_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockIncludingCommitmentSharesMember_z6LOpIPL6A33" title="Number of shares issued, shares"&gt;0&lt;/span&gt;) shares of common stock under
the 2023 Purchase Agreement, including &lt;span id="xdx_902_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockExcludingCommitmentSharesMember_zKHtPnsEnjXa" title="Number of shares issued, shares"&gt;3,275,000&lt;/span&gt; (2022: &lt;span id="xdx_90A_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockExcludingCommitmentSharesMember_zYwnI6VFVwnc" title="Number of shares issued, shares"&gt;0&lt;/span&gt;) shares of common stock for aggregate proceeds of $&lt;span id="xdx_90D_eus-gaap--StockIssuedDuringPeriodValueNewIssues_pn5n6_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zzlbzAywYWSf" title="Number of shares issued, value"&gt;27.9&lt;/span&gt; million (2022: $&lt;span id="xdx_904_eus-gaap--StockIssuedDuringPeriodValueNewIssues_pn5n6_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zaJiVBhsgBWg" title="Number of shares issued, value"&gt;0&lt;/span&gt;)
and&#160;&lt;span id="xdx_907_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommitmentSharesMember_znaRV435uB97" title="Number of shares issued, shares"&gt;13,943&lt;/span&gt;&#160;(2022:&#160;&lt;span id="xdx_900_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommitmentSharesMember_znqFy6tpohz1" title="Number of shares issued, shares"&gt;0&lt;/span&gt;) commitment shares.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;At
September 30, 2023, an amount of $&lt;span id="xdx_903_eus-gaap--StockIssuedDuringPeriodValueOther_pn5n6_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2023Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zO9v6gY7XRR7" title="Amount of shares remain available"&gt;122.1&lt;/span&gt; million remained available under the 2023 Purchase Agreement.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;2019
Purchase Agreement&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;On
June 7, 2019, the Company entered into a $50.0 million purchase agreement (the &#x201c;2019 Purchase Agreement&#x201d;) with Lincoln Park,
as amended on July 1, 2020, pursuant to which the Company had the right to sell and issue to Lincoln Park, and Lincoln Park was obligated
to purchase, up to $&lt;span id="xdx_90E_ecustom--ValueOfSharesObligatedToPurchase_pn6n6_c20230202__20230203__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zcrfomPkYdqb" title="Value of shares obligated to purchase"&gt;50&lt;/span&gt;.0 million in value of its shares of common stock from time to time over a three-year period until July 1, 2022.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;During
the year ended September 30, 2023 and 2022, the Company did not issue any shares to Lincoln Park under the 2019 Purchase Agreement.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;During
the year ended September 30, 2021, the Company issued to Lincoln Park an aggregate of &lt;span id="xdx_903_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockIncludingCommitmentSharesMember_znOth4NjnOii" title="Number of shares issued, shares"&gt;4,086,209&lt;/span&gt; shares of common stock under the 2019
Purchase Agreement, including &lt;span id="xdx_901_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommonStockExcludingCommitmentSharesMember_zT70L5cMjiab" title="Number of shares issued, shares"&gt;4,007,996&lt;/span&gt; shares of common stock for an aggregate purchase price of $&lt;span id="xdx_905_eus-gaap--StockIssuedDuringPeriodValueNewIssues_pn5n6_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__us-gaap--CommonStockMember_zhdeqeVovxv4" title="Number of shares issued, value"&gt;24.1&lt;/span&gt; million and &lt;span id="xdx_905_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_c20201001__20210930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember__us-gaap--StatementClassOfStockAxis__custom--CommitmentSharesMember_zNPOHsOEFG8g" title="Number of shares issued, shares"&gt;78,213&lt;/span&gt; commitment
shares.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;At
September 30, 2023 and 2022, &lt;span id="xdx_907_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_do_c20221001__20230930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zxh1eYR61Yfc" title="Number of shares issued, shares"&gt;&lt;span id="xdx_901_eus-gaap--StockIssuedDuringPeriodSharesNewIssues_pip0_do_c20211001__20220930__us-gaap--TypeOfArrangementAxis__custom--PurchaseAgreement2019Member__dei--LegalEntityAxis__custom--LincolnParkCapitalFundLLCMember_zTTuLXokmTC5" title="Number of shares issued, shares"&gt;no&lt;/span&gt;&lt;/span&gt; shares remained available for issuance under the 2019 Purchase Agreement.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</avxl:EquityOfferingTextBlock>
    <us-gaap:SaleOfStockNumberOfSharesIssuedInTransaction
      contextRef="From2021-06-212021-06-22_custom_SecuritiesPurchaseAgreementMember"
      decimals="INF"
      unitRef="Shares">2380953</us-gaap:SaleOfStockNumberOfSharesIssuedInTransaction>
    <us-gaap:SaleOfStockPricePerShare
      contextRef="AsOf2021-06-22_custom_SecuritiesPurchaseAgreementMember"
      decimals="INF"
      unitRef="USDPShares">21</us-gaap:SaleOfStockPricePerShare>
    <us-gaap:SaleOfStockConsiderationReceivedOnTransaction
      contextRef="From2021-06-212021-06-22_custom_SecuritiesPurchaseAgreementMember"
      decimals="-6"
      unitRef="USD">50000000</us-gaap:SaleOfStockConsiderationReceivedOnTransaction>
    <us-gaap:ProceedsFromIssuanceInitialPublicOffering
      contextRef="From2021-06-212021-06-22_custom_SecuritiesPurchaseAgreementMember"
      decimals="0"
      unitRef="USD">46902981</us-gaap:ProceedsFromIssuanceInitialPublicOffering>
    <avxl:PercentageOfGrossProceedsFromSales
      contextRef="From2022-10-012023-09-30_custom_EquityOfferingSalesAgreementMember"
      decimals="INF"
      unitRef="Pure">0.030</avxl:PercentageOfGrossProceedsFromSales>
    <us-gaap:SaleOfStockNumberOfSharesIssuedInTransaction
      contextRef="From2022-10-012023-09-30_custom_EquityOfferingSalesAgreementMember"
      decimals="INF"
      unitRef="Shares">0</us-gaap:SaleOfStockNumberOfSharesIssuedInTransaction>
    <us-gaap:SaleOfStockNumberOfSharesIssuedInTransaction
      contextRef="From2021-10-012022-09-30_custom_EquityOfferingSalesAgreementMember"
      decimals="INF"
      unitRef="Shares">1623813</us-gaap:SaleOfStockNumberOfSharesIssuedInTransaction>
    <us-gaap:SaleOfStockConsiderationReceivedPerTransaction
      contextRef="From2021-10-012022-09-30_custom_EquityOfferingSalesAgreementMember"
      decimals="-6"
      unitRef="USD">21000000</us-gaap:SaleOfStockConsiderationReceivedPerTransaction>
    <us-gaap:ProceedsFromIssuanceInitialPublicOffering
      contextRef="From2021-10-012022-09-30_custom_EquityOfferingSalesAgreementMember"
      decimals="-5"
      unitRef="USD">20300000</us-gaap:ProceedsFromIssuanceInitialPublicOffering>
    <us-gaap:SaleOfStockNumberOfSharesIssuedInTransaction
      contextRef="From2020-10-012021-09-30_custom_EquityOfferingSalesAgreementMember"
      decimals="INF"
      unitRef="Shares">5634576</us-gaap:SaleOfStockNumberOfSharesIssuedInTransaction>
    <avxl:SoldForGrossProceedsAmount
      contextRef="From2020-10-012021-09-30_custom_EquityOfferingSalesAgreementMember"
      decimals="-5"
      unitRef="USD">79100000</avxl:SoldForGrossProceedsAmount>
    <us-gaap:ProceedsFromIssuanceInitialPublicOffering
      contextRef="From2020-10-012021-09-30_custom_EquityOfferingSalesAgreementMember"
      decimals="-5"
      unitRef="USD">76700000</us-gaap:ProceedsFromIssuanceInitialPublicOffering>
    <avxl:SalesOfAgreementAmount contextRef="AsOf2023-09-30" decimals="-5" unitRef="USD">142400000</avxl:SalesOfAgreementAmount>
    <avxl:SalesOfAgreementAmount contextRef="AsOf2022-09-30" decimals="-5" unitRef="USD">142400000</avxl:SalesOfAgreementAmount>
    <avxl:ValueOfSharesObligatedToPurchase
      contextRef="From2023-02-022023-02-03_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember"
      decimals="-6"
      unitRef="USD">150000000</avxl:ValueOfSharesObligatedToPurchase>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="From2023-02-022023-02-03_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember"
      decimals="INF"
      unitRef="Shares">75000</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <avxl:NumberOfSharesObligatedToPurchaseProrataBasic
      contextRef="From2023-02-022023-02-03_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember"
      decimals="INF"
      unitRef="Shares">75000</avxl:NumberOfSharesObligatedToPurchaseProrataBasic>
    <us-gaap:ProceedsFromIssuanceOrSaleOfEquity
      contextRef="From2023-02-022023-02-03_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember"
      decimals="-6"
      unitRef="USD">150000000</us-gaap:ProceedsFromIssuanceOrSaleOfEquity>
    <avxl:FairValueOfInitialCommitment contextRef="AsOf2023-09-30" decimals="-5" unitRef="USD">800000</avxl:FairValueOfInitialCommitment>
    <avxl:IncurredExpenses contextRef="AsOf2023-09-30" decimals="-5" unitRef="USD">100000</avxl:IncurredExpenses>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockIncludingCommitmentSharesMember"
      decimals="INF"
      unitRef="Shares">3288943</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockIncludingCommitmentSharesMember"
      decimals="INF"
      unitRef="Shares">0</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockExcludingCommitmentSharesMember"
      decimals="INF"
      unitRef="Shares">3275000</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockExcludingCommitmentSharesMember"
      decimals="INF"
      unitRef="Shares">0</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:StockIssuedDuringPeriodValueNewIssues
      contextRef="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember"
      decimals="-5"
      unitRef="USD">27900000</us-gaap:StockIssuedDuringPeriodValueNewIssues>
    <us-gaap:StockIssuedDuringPeriodValueNewIssues
      contextRef="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember"
      decimals="-5"
      unitRef="USD">0</us-gaap:StockIssuedDuringPeriodValueNewIssues>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommitmentSharesMember"
      decimals="INF"
      unitRef="Shares">13943</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="From2021-10-012022-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember_custom_CommitmentSharesMember"
      decimals="INF"
      unitRef="Shares">0</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:StockIssuedDuringPeriodValueOther
      contextRef="From2022-10-012023-09-30_custom_PurchaseAgreement2023Member_custom_LincolnParkCapitalFundLLCMember"
      decimals="-5"
      unitRef="USD">122100000</us-gaap:StockIssuedDuringPeriodValueOther>
    <avxl:ValueOfSharesObligatedToPurchase
      contextRef="From2023-02-022023-02-03_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember"
      decimals="-6"
      unitRef="USD">50000000</avxl:ValueOfSharesObligatedToPurchase>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockIncludingCommitmentSharesMember"
      decimals="INF"
      unitRef="Shares">4086209</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_custom_CommonStockExcludingCommitmentSharesMember"
      decimals="INF"
      unitRef="Shares">4007996</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:StockIssuedDuringPeriodValueNewIssues
      contextRef="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_us-gaap_CommonStockMember"
      decimals="-5"
      unitRef="USD">24100000</us-gaap:StockIssuedDuringPeriodValueNewIssues>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="From2020-10-012021-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember_custom_CommitmentSharesMember"
      decimals="INF"
      unitRef="Shares">78213</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="From2022-10-012023-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember"
      decimals="INF"
      unitRef="Shares">0</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:StockIssuedDuringPeriodSharesNewIssues
      contextRef="From2021-10-012022-09-30_custom_PurchaseAgreement2019Member_custom_LincolnParkCapitalFundLLCMember"
      decimals="INF"
      unitRef="Shares">0</us-gaap:StockIssuedDuringPeriodSharesNewIssues>
    <us-gaap:CommitmentsDisclosureTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_802_eus-gaap--CommitmentsDisclosureTextBlock_zE2pkYALuI52" style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;Note
6	&lt;span id="xdx_82F_zcntuv9Owit"&gt;Commitments and Contingencies&lt;/span&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;Lease&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;The
Company leases office space under an operating lease with an initial term of &lt;span id="xdx_909_eus-gaap--OperatingLeaseWeightedAverageRemainingLeaseTerm1_iI_dtM_c20230930_zGILsxUCfssh" title="Operating lease term"&gt;12&lt;/span&gt; months or less. Under the terms of the office lease,
the Company is required to pay its proportionate share of operating costs. &lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;The
operating lease costs were as follows (in thousands):&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;&#160;&lt;/span&gt;&lt;/p&gt;







&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;/p&gt;







&lt;table cellpadding="0" cellspacing="0" id="xdx_892_eus-gaap--LeaseCostTableTextBlock_pn3n3_zebQe0HUsBil" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse" summary="xdx: Disclosure - Commitments and Contingencies (Details)"&gt;
  &lt;tr style="vertical-align: bottom"&gt;
    &lt;td style="text-align: left"&gt;&lt;span id="xdx_8BD_zRdYsDhim6L" style="display: none"&gt;Schedule of operating lease costs&lt;/span&gt;&lt;/td&gt;
    &lt;td&gt;&#160;&lt;/td&gt;
    &lt;td colspan="3" id="xdx_497_20221001__20230930_zoFz6uIyoz5h" style="text-align: center"&gt;&#160;&lt;/td&gt;
    &lt;td&gt;&#160;&lt;/td&gt;
    &lt;td colspan="3" id="xdx_497_20211001__20220930_zWLZSQljBpKc" style="text-align: center"&gt;&#160;&lt;/td&gt;
    &lt;td&gt;&#160;&lt;/td&gt;
    &lt;td colspan="3" id="xdx_496_20201001__20210930_zMlBeHRgn1ej" style="text-align: center"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
    &lt;td style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="11" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;September
    30,&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
  &lt;tr style="vertical-align: bottom"&gt;
    &lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;2023&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;2022&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;2021&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
  &lt;tr id="xdx_400_eus-gaap--OperatingLeaseCost_zNr7fwUnSpa" style="vertical-align: bottom; background-color: #CCEEFF"&gt;
    &lt;td style="width: 55%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Operating lease costs&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;118&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;73&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;$&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;131&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
  &lt;/table&gt;

&lt;p id="xdx_8A5_zYMkVcWgWcFj" style="margin-top: 0; margin-bottom: 0"&gt;&#160;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;Employee
401(k) Benefit Plan&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;The
Company has a defined-contribution savings plan under Section 401(k) of the Internal Revenue Code. The plan covers all United States
based employees. United States based employees eligible to participate in the plan may contribute up to the current statutory limits
under the Internal Revenue Service regulations. The 401(k) plan permits the Company to make additional matching contributions on behalf
of contributing employees. &lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;During
the year ended September 30, 2023, the Company made matching contributions under the 401(k) plan as follows (in thousands):&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 9pt Sans-Serif; margin: 0; color: Red"&gt;&lt;/p&gt;

&lt;table cellpadding="0" cellspacing="0" id="xdx_89F_eus-gaap--DefinedContributionPlanDisclosuresTableTextBlock_pn3n3_z6GAoPcUR2E" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse" summary="xdx: Disclosure - Commitments and Contingencies (Details 1)"&gt;
  &lt;tr style="vertical-align: bottom"&gt;
    &lt;td style="text-align: left"&gt;&lt;span id="xdx_8B6_zNZ0ix4JlNLb" style="display: none"&gt;Schedule of contributions under the  plan&lt;/span&gt;&lt;/td&gt;
    &lt;td&gt;&#160;&lt;/td&gt;
    &lt;td colspan="3" id="xdx_497_20221001__20230930_zA0qushBeCO8" style="text-align: center"&gt;&#160;&lt;/td&gt;
    &lt;td&gt;&#160;&lt;/td&gt;
    &lt;td colspan="3" id="xdx_497_20211001__20220930_zj5JX4iHu8rg" style="text-align: center"&gt;&#160;&lt;/td&gt;
    &lt;td&gt;&#160;&lt;/td&gt;
    &lt;td colspan="3" id="xdx_496_20201001__20210930_zJ6NvaX8QTVe" style="text-align: center"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
    &lt;td style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="11" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;September
    30,&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
  &lt;tr style="vertical-align: bottom"&gt;
    &lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;2023&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;2022&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;2021&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
  &lt;tr id="xdx_40C_eus-gaap--PensionContributions_zAjEbuXkDcDj" style="vertical-align: bottom; background-color: #CCEEFF"&gt;
    &lt;td style="width: 55%"&gt;&lt;p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Contributions
                           to 401(k) plan&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;
    &lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;232&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;158&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;$&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;129&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
  &lt;/table&gt;
&lt;p style="font: 9pt Sans-Serif; margin: 0; color: Red"&gt;&lt;/p&gt;

&lt;p id="xdx_8AB_zFJSuoNaYAbd" style="font: 10pt Times New Roman, Times, Serif; margin: 0; color: gray"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;Litigation&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt; background-color: white"&gt;The
Company is subject to claims and legal proceedings that arise in the ordinary course of business. Such matters are inherently uncertain,
and there can be no guarantee that the outcome of any such matter will be decided favorably to the Company or that the resolution of
any such matter will not have a material adverse effect upon the Company&#x2019;s consolidated financial statements. The Company does
not believe that any of such pending claims and legal proceedings will have a material adverse effect on its consolidated financial statements.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;Share
Purchase Warrants&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;At
September 30, 2023 and 2022, the Company had &lt;span id="xdx_905_eus-gaap--ClassOfWarrantOrRightOutstanding_iI_pip0_c20230930_zU9Dso551HI8" title="Warrants outstanding"&gt;&lt;span id="xdx_909_eus-gaap--ClassOfWarrantOrRightOutstanding_iI_pip0_c20220930_zaTuvrBJTgF3" title="Warrants outstanding"&gt;160,000&lt;/span&gt;&lt;/span&gt; warrants outstanding at a weighted average exercise price of $&lt;span id="xdx_909_ecustom--WarrantsOutstandingWeightedAverageExercise_iI_pip0_c20230930_z3kK5IwtA6el" title="Warrants outstanding weighted average exercise price"&gt;&lt;span id="xdx_907_ecustom--WarrantsOutstandingWeightedAverageExercise_iI_pip0_c20220930_z5jtuo1qpm66" title="Warrants outstanding weighted average exercise price"&gt;3.72&lt;/span&gt;&lt;/span&gt; as follows:&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;table cellpadding="0" cellspacing="0" id="xdx_89E_ecustom--ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock_zKmN5o46PFt7" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 2)"&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="3" style="text-align: left"&gt;&lt;span id="xdx_8B6_zdQIUyosHM7i" style="display: none"&gt;Schedule of share purchase warrants outstanding&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Number&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: center; padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Exercise Price&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: center; padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Expiry Date&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants1Member_z7DIAed1ljy5" style="width: 26%; text-align: right" title="Number of warrants outstanding"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;150,000&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 8%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants1Member_zSEBrQgKsBAa" style="width: 26%; text-align: right" title="Exercise Price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3.17&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 8%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 26%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_906_eus-gaap--WarrantsAndRightsOutstandingMaturityDate_iI_dd_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants1Member_z4XXQCR7NqKd" title="Expiry Date"&gt;May 6, 2024&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants2Member_zek8ir0OxIK2" style="border-bottom: Black 1pt solid; text-align: right" title="Number of warrants outstanding"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;10,000&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants2Member_zckHC5eaRJ0f" style="border-bottom: Black 1pt solid; text-align: right" title="Exercise Price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;12.00&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_903_eus-gaap--WarrantsAndRightsOutstandingMaturityDate_iI_dd_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants2Member_zCjIeYOFUu0j" title="Expiry Date"&gt;April 21, 2026&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_iI_pip0_c20230930_z1GBMONfXrj9" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of warrants outstanding"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;160,000&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; text-align: right"&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font: 12pt Times New Roman, Times, Serif; padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font: 12pt Times New Roman, Times, Serif; padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; font: 12pt Times New Roman, Times, Serif; text-align: right"&gt;&lt;/td&gt;
&lt;td style="font: 12pt Times New Roman, Times, Serif; padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;



&lt;p id="xdx_8A9_znw7vZXUMsdd" style="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 42.55pt; text-align: left; text-indent: -0.8pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;Stock&#x2013;based
Compensation Plan&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; color: gray"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;2015
Stock Option Plan&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;On
September 18, 2015, the Company&#x2019;s board of directors approved a 2015 Omnibus Incentive Plan (the &#x201c;2015 Plan&#x201d;), which
provided for the grant of stock options and restricted stock awards to directors, officers, employees and consultants of the Company.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
maximum number of our common shares reserved for issue under the plan was &lt;span id="xdx_90D_eus-gaap--CommonStockCapitalSharesReservedForFutureIssuance_iI_pip0_c20230930__us-gaap--PlanNameAxis__custom--StockOptionPlan2015Member_zZgMGE32sSjk" title="Maximum number of common shares reserved for future issuance"&gt;6,050,553&lt;/span&gt; shares, subject to adjustment in the event of a change
of the Company&#x2019;s capitalization.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;





&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;/span&gt;&lt;b&gt;&lt;/b&gt;&lt;/p&gt;









&lt;p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;2019
Stock Option Plan&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;


&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;On
January 15, 2019, the Board approved the 2019 Omnibus Incentive Plan (the &#x201c;2019 Plan&#x201d;), which provides for the grant of stock
options and restricted stock awards to directors, officers, employees, consultants and advisors of the Company.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
maximum number of our common shares reserved for issue under the plan was &lt;span id="xdx_904_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_pip0_c20221001__20230930__us-gaap--PlanNameAxis__custom--StockOptionPlan2019Member_zE2xKSnfxfMj" title="Additional shares of common stock available for issuance"&gt;6,000,000&lt;/span&gt; shares, subject to adjustment in the event of a change
of the Company&#x2019;s capitalization.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;During
the year ended September 30, 2022, &lt;span id="xdx_90D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod_pip0_c20211001__20220930__us-gaap--PlanNameAxis__custom--StockOptionPlan2022Member_zPiZBJkKUDba" title="Option granted"&gt;406,453&lt;/span&gt; options previously available under the 2019 Plan and the 2015 Plan became available under
the 2022 Plan (as defined below).&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;2022
Stock Option Plan&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&lt;i&gt;&#160;&lt;/i&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;On
March 25, 2022, the Board approved the 2022 Omnibus Incentive Plan (the &#x201c;2022 Plan&#x201d;). The 2022 Plan was approved by stockholders
on May 24, 2022. Under the terms of the 2022 Plan, &lt;span id="xdx_908_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_pip0_c20220324__20220325__us-gaap--PlanNameAxis__custom--StockOptionPlan2022Member_zCVPF6lGfzz6" title="Additional shares of common stock available for issuance"&gt;10,000,000&lt;/span&gt; additional shares of Common Stock will be available for issuance under
the plan, in addition to the shares available under the 2019 Plan and the 2015 Plan. Any awards outstanding under a previous stock option
plan will remain subject to and be paid under such plan, and any shares subject to outstanding awards under a previous plan that subsequently
cease to be subject to such awards (other than by reason of settlement of the awards in shares) will automatically become available for
issuance under the 2022 Plan.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
2022 Plan provides that it may be administered by the Board, or the Board may delegate such responsibility to a committee. The exercise
price will be determined by the Board at the time of grant shall be at least equal to the fair market value on such date. If the grantee
is a 10% stockholder on the grant date, then the exercise price shall not be less than 110% of fair market value of the Company&#x2019;s
shares of common stock on the grant date. Stock options may be granted under the 2022 Plan for an exercise period of up to ten years
from the date of grant of the option or such lesser periods as may be determined by the Board, subject to earlier termination in accordance
with the terms of the 2022 Plan. At September 30, 2023, &lt;span id="xdx_904_ecustom--OptionIssued_pip0_c20221001__20230930_zECMzajbkxMi" title="Option issued"&gt;3,849,917&lt;/span&gt; options had been issued under the 2022 Plan and &lt;span id="xdx_900_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_iI_pip0_c20230930__us-gaap--PlanNameAxis__custom--StockOptionPlan2022Member_zT6pYBZ4Zee1" title="Option available issue"&gt;6,661,535&lt;/span&gt; options were
available for issue under the 2022 Plan, subject to stockholder approval.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
following summarizes information about stock option activity during the years ended September 30, 2023 and 2022:&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;table cellpadding="0" cellspacing="0" id="xdx_890_eus-gaap--ScheduleOfStockOptionsRollForwardTableTextBlock_zahdwjh2ktsa" style="font: 9.5pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 3)"&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span id="xdx_8B4_zBRZ0wob6U9d" style="display: none"&gt;Schedule of stock option activity&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Weighted&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Weighted Average&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Average Grant&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Aggregate intrinsic&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Number of&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Exercise Price&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Date Fair Value&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;value&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Options&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;($)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;($)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;($)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; width: 18%; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Outstanding,
September 30, 2021&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 3%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iS_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zaQEDt8Geqwg" style="width: 16%; text-align: right" title="Number of options, Outstanding beginning balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;11,330,903&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 3%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iS_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zvh9J0z6rNSg" style="width: 16%; text-align: right" title="Weighted average exercise price, Outstanding beginning balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5.74&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 3%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_iS_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zm8JuTSr9WZg" style="width: 15%; text-align: right" title="Weighted average grant date fair value, Outstanding beginning balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl0768"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 3%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_iS_pp0p0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zMVx9451Ez4i" style="width: 15%; text-align: right" title="Aggregate intrinsic value, Outstanding beginning balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;140,132,451&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Granted&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zYDHLx1xNqd" style="text-align: right" title="Number of options, Granted"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,358,000&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_za6WMoclHJt6" style="text-align: right" title="Weighted average exercise price, Granted"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;10.13&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z12ur8IugGNa" style="text-align: right" title="Weighted average grant date fair value, Granted"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;7.07&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Forfeited&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_iN_pip0_di_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zzqgqYLwD0x8" style="text-align: right" title="Number of options, Forfeited"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(118,750&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98F_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zz0JNU8yhYOi" style="text-align: right" title="Weighted average exercise price, Forfeited"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;6.86&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_980_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zd5Dfy6k0HWb" style="text-align: right" title="Weighted average grant date fair value, Forfeited"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5.23&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Exercised&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--StockIssuedDuringPeriodSharesStockOptionsExercised_iN_pip0_di_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zLVBhCdfo3v2" style="border-bottom: Black 1pt solid; text-align: right" title="Number of options, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(400,537&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zNtv4tKDm84l" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2.52&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zyXGXeuunFo" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average grant date fair value, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1.88&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_pp0p0" style="border-bottom: Black 1pt solid; text-align: right" title="Aggregate intrinsic value, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;4,201,015&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Outstanding,
September 30, 2022&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_983_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iS_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zF1F2l3FFbvl" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of options, Outstanding beginning balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;13,169,616&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iS_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zDoB5pRDMJR8" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price, Outstanding beginning balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;6.61&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; color: white; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_985_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_iS_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zP01qsGKaijj" style="border-bottom: Black 2.5pt double; font: normal 10pt Times New Roman, Times, Serif; text-align: right" title="Weighted average grant date fair value, Outstanding beginning balance"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;4.96&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; color: white; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_iS_pp0p0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zoFSMXIeupJ3" style="border-bottom: Black 2.5pt double; text-align: right" title="Aggregate intrinsic value, Outstanding beginning balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;62,267,309&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Granted&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zdGzYZ6nAJ19" style="text-align: right" title="Number of options, Granted"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,959,000&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zZhiagjQKbJd" style="text-align: right" title="Weighted average exercise price, Granted"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;9.30&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_985_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_ziClWNBA0fig" style="text-align: right" title="Weighted average grant date fair value, Granted"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;6.60&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Expired&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Exercised&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_981_eus-gaap--StockIssuedDuringPeriodSharesStockOptionsExercised_iN_pip0_di_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zlKT4O9ITNx2" style="text-align: right" title="Number of options, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(759,753&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zjRxv8zRZ3s6" style="text-align: right" title="Weighted average exercise price, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2.34&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_987_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z3bIctfsRpu9" style="text-align: right" title="Weighted average grant date fair value, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;0.95&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_983_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_pp0p0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zumLJJKYvL95" style="text-align: right" title="Aggregate intrinsic value, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;4,629,026&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Forfeited&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_985_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_iN_pip0_di_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zcgXAyqtdxn7" style="text-align: right" title="Number of options, Forfeited"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(257,083&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z189xmJSdqYh" style="text-align: right" title="Weighted average exercise price, Forfeited"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;12.00&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98E_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zPz67mlunnO8" style="text-align: right" title="Weighted average grant date fair value, Forfeited"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;6.74&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Cancelled&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Outstanding,
September 30, 2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iE_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zwxfgYOA6xzc" style="border-bottom: Black 1pt solid; text-align: right" title="Number of options, Outstanding ending balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;14,111,780&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iE_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zDKIrfhkqrwi" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price, Outstanding ending balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;7.12&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; color: white; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_iE_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z8QNfw1Q0kMg" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average grant date fair value,  Outstanding ending balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5.27&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; color: white; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_iE_pp0p0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zevpgIbVICHg" style="border-bottom: Black 1pt solid; text-align: right" title="Aggregate intrinsic value, Outstanding ending balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;22,290,069&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Exercisable,
September 30, 2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zJW8NDpTVbOa" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of options, Exercisable"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;9,604,614&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zhq3b5hS8iE" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price, Exercisable"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5.19&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; color: white; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z7ZLBQG8DOQ9" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average grant date fair value, Exercisable"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3.94&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; color: white; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_iI_pp0p0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zde5865tfxlf" style="border-bottom: Black 2.5pt double; text-align: right" title="Aggregate intrinsic value, Exercisable"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;22,290,069&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;



&lt;p id="xdx_8AD_zEuKBqIga3vj" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
following summarizes information about stock options at September 30, 2023 by a range of exercise prices:&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;table cellpadding="0" cellspacing="0" id="xdx_89A_eus-gaap--ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_zEoDtaKA8WQ4" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 4)"&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: left"&gt;&lt;span id="xdx_8B5_zZ1azt0WqCG3" style="display: none"&gt;Schedule of summarizes information about stock options&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Weighted&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;average&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Weighted&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Number of&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;remaining&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;average&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Weighted&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="7" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Range of exercises
prices&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;outstanding&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;contractual&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;exercise&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Number of&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;average&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;From&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;To&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;options&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;life&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;price&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;vested options&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;exercise price&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_985_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zJYXBWgUxKda" style="width: 11%; text-align: right" title="Range of exercise prices, Lower range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;0.92&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_980_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_znfdhmj2ADy3" style="width: 11%; text-align: right" title="Range of exercise prices, Upper range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3.00&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zik41maNOF0h" style="width: 11%; text-align: right" title="Number of outstanding options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3,280,309&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_903_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zOoekuBKWZEa" title="Weighted average remaining contractual life"&gt;4.74&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zJmshsBbEIab" style="width: 10%; text-align: right" title="Weighted average exercise price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2.39&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_987_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zbnUPrIBpwV2" style="width: 10%; text-align: right" title="Number of vested options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3,280,309&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_z9mbrl6XrXf" style="width: 10%; text-align: right" title="Weighted average exercise price options vested"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2.39&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_986_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_z7Y8nycQuh9a" style="text-align: right" title="Range of exercise prices, Lower range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3.01&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98B_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_z086mh1eEJ4h" style="text-align: right" title="Range of exercise prices, Upper range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5.00&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zWp1gnuPFd1h" style="text-align: right" title="Number of outstanding options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,017,500&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90D_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zfpbf6GJ6g7c" title="Weighted average remaining contractual life"&gt;4.32&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zCMjYCjifoc" style="text-align: right" title="Weighted average exercise price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3.28&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zw5cQQ4bQl4a" style="text-align: right" title="Number of vested options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,017,500&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_ze2Cbpm9tHh3" style="text-align: right" title="Weighted average exercise price options vested"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3.28&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zfnYJas5hHn5" style="text-align: right" title="Range of exercise prices, Lower range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5.01&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_985_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zjw2rHU2tdde" style="text-align: right" title="Range of exercise prices, Upper range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;9.00&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zJwiUtbGVNFa" style="text-align: right" title="Number of outstanding options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5,260,054&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_903_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zv4ZErt5pUja" title="Weighted average remaining contractual life"&gt;6.21&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zAumZywNL2Bk" style="text-align: right" title="Weighted average exercise price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;6.90&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zKxXBt473Zje" style="text-align: right" title="Number of vested options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3,304,137&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zr1Kzn0lL1M5" style="text-align: right" title="Weighted average exercise price options vested"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;6.10&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_982_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zLMY1YARIpUe" style="text-align: right" title="Range of exercise prices, Lower range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;9.01&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_984_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_z4hniAZlE363" style="text-align: right" title="Range of exercise prices, Upper range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;13.00&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zJdUNRWEL8Ql" style="text-align: right" title="Number of outstanding options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,981,917&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90D_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zVADhDSFa35f" title="Weighted average remaining contractual life"&gt;8.37&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_z7Spxmdt2g87" style="text-align: right" title="Weighted average exercise price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;10.55&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_980_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zm06iu99nx94" style="text-align: right" title="Number of vested options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;480,584&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zVXTV9kNNHI3" style="text-align: right" title="Weighted average exercise price options vested"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;11.45&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zMWFZE1Vdnyc" style="text-align: right" title="Range of exercise prices, Lower range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;13.01&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zoLuZjUZdnX4" style="text-align: right" title="Range of exercise prices, Upper range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;25.00&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_z8NHOEOWSvB9" style="border-bottom: Black 1pt solid; text-align: right" title="Number of outstanding options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,572,000&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zLQK7QouAmE9" title="Weighted average remaining contractual life"&gt;7.49&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zTu44CHbESU8" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;18.29&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_982_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zekHKoPStc37" style="border-bottom: Black 1pt solid; text-align: right" title="Number of vested options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;522,084&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zaAU3Mj6dCX1" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price options vested"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;18.57&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="font-size: 10pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt; text-align: right"&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-size: 10pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-size: 10pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt; text-align: right"&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-size: 10pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zt2AET0WMtzk" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of outstanding options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;14,111,780&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90B_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zrvSy6PHWlcg" title="Weighted average remaining contractual life"&gt;6.04&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zz5zxf8fZNo8" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;7.12&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_984_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zQ4zwY5uofia" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of vested options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;9,604,614&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zvNCPuWNKxpi" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price options vested"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5.19&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;



&lt;p id="xdx_8A4_zmiwvETXlO4e" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;
















&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
weighted average per share fair value of options vested during the year ended September 30, 2023 was $&lt;span id="xdx_90F_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_pip0_c20221001__20230930_zhxiHcVEOz8" title="Weighted average grant date fair value of options vested"&gt;3.94&lt;/span&gt; (2022: $&lt;span id="xdx_90F_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_pip0_c20211001__20220930_zQQWTKVXN7j2" title="Weighted average grant date fair value of options vested"&gt;4.69&lt;/span&gt;, 2021: $&lt;span id="xdx_905_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_pip0_c20201001__20210930_zEZMrPGIxEC1" title="Weighted average grant date fair value of options vested"&gt;2.54&lt;/span&gt;).
At September 30, 2023, the weighted average contractual life of options outstanding was &lt;span id="xdx_903_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930_zBHZY8takBBa" title="Weighted average contractual life of options outstanding"&gt;6.0&lt;/span&gt; years (2022: &lt;span id="xdx_905_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20211001__20220930_zTFCW5ySvsgf" title="Weighted average contractual life of options outstanding"&gt;6.4&lt;/span&gt; years) and for options exercisable
was &lt;span id="xdx_904_eus-gaap--SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930_z7IOtwJb2Aoj" title="Options exercisable"&gt;4.75&lt;/span&gt; years (2022: &lt;span id="xdx_904_eus-gaap--SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_dtY_c20211001__20220930_zEa7SxOeqOih" title="Options exercisable"&gt;5.1&lt;/span&gt; years).&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
aggregate intrinsic value is calculated as the difference between the exercise price of the underlying awards and the quoted market price
of the Company&#x2019;s stock for the options that were in-the-money at September 30, 2023.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;	The
Company recognized stock-based compensation expense of $&lt;span id="xdx_909_eus-gaap--AllocatedShareBasedCompensationExpense_pn5n6_c20221001__20230930_zH6p6tZw0jW" title="Share based compensation"&gt;16.4&lt;/span&gt; million during the year ended September 30, 2023 (2022: $&lt;span id="xdx_90A_eus-gaap--AllocatedShareBasedCompensationExpense_pn5n6_c20211001__20220930_zGbryIoD3SS9" title="Share based compensation"&gt;18.4&lt;/span&gt; million; 2021:
$&lt;span id="xdx_907_eus-gaap--AllocatedShareBasedCompensationExpense_pn5n6_c20201001__20210930_zksFCXqaXAHj" title="Share based compensation"&gt;8.2&lt;/span&gt; million) in connection with the issuance and vesting 	of stock options in exchange for services. These amounts have been included
in general and 	administrative expenses and research and development expenses on the Company&#x2019;s consolidated statements of 	operations
as follows (in thousands):&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;/p&gt;&lt;p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"&gt;&lt;/p&gt;

&lt;p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"&gt;&lt;/p&gt;


&lt;table cellpadding="0" cellspacing="0" id="xdx_893_eus-gaap--ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_pn3n3_zi05WuRK54V9" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 5)"&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span id="xdx_8B0_zVkn5OI5YY12" style="display: none"&gt;Schedule of general and administrative expenses and research and development expenses&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="11" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;September
30,&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2022&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;General
and administrative&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98A_eus-gaap--ShareBasedCompensation_pn3n3_c20221001__20230930__us-gaap--IncomeStatementLocationAxis__us-gaap--GeneralAndAdministrativeExpenseMember_zlegHFiNw3u9" style="width: 11%; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5,558&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--ShareBasedCompensation_pn3n3_c20211001__20220930__us-gaap--IncomeStatementLocationAxis__us-gaap--GeneralAndAdministrativeExpenseMember_zt8VbpPKl4ri" style="width: 11%; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;7,129&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--ShareBasedCompensation_pn3n3_c20201001__20210930__us-gaap--IncomeStatementLocationAxis__us-gaap--GeneralAndAdministrativeExpenseMember_ztXzYhbjPTtj" style="width: 11%; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3,571&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Research
and development&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98E_eus-gaap--ShareBasedCompensation_pn3n3_c20221001__20230930__us-gaap--IncomeStatementLocationAxis__us-gaap--ResearchAndDevelopmentExpenseMember_zxlwTaY7roA2" style="border-bottom: Black 1pt solid; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;10,812&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_982_eus-gaap--ShareBasedCompensation_pn3n3_c20211001__20220930__us-gaap--IncomeStatementLocationAxis__us-gaap--ResearchAndDevelopmentExpenseMember_zMnF2RIYqYD7" style="border-bottom: Black 1pt solid; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;11,250&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_987_eus-gaap--ShareBasedCompensation_pn3n3_c20201001__20210930__us-gaap--IncomeStatementLocationAxis__us-gaap--ResearchAndDevelopmentExpenseMember_zbbLNUWHcCQk" style="border-bottom: Black 1pt solid; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;4,660&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Total
stock-based compensation&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_983_eus-gaap--ShareBasedCompensation_pn3n3_c20221001__20230930_zBefjtLfXJBl" style="border-bottom: Black 2.5pt double; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;16,370&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_985_eus-gaap--ShareBasedCompensation_pn3n3_c20211001__20220930_zJqVKJNEeNN2" style="border-bottom: Black 2.5pt double; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;18,379&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--ShareBasedCompensation_pn3n3_c20201001__20210930_zNPDO6PYdgbh" style="border-bottom: Black 2.5pt double; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;8,231&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;



&lt;p id="xdx_8A1_zEmZAKeGAs8d" style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;An
amount of approximately $&lt;span id="xdx_90F_eus-gaap--EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_iI_pn5n6_c20230930_zHwO246Nknc7" title="Remaining stock based compensation"&gt;14.1 &lt;/span&gt;million in stock-based compensation is expected to be recorded over the remaining term 	of such options
and warrants through fiscal 2026.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
fair value of each option and warrant award is estimated on the date of grant using the Black Scholes option pricing model based on the
following weighted average assumptions:&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;table cellpadding="0" cellspacing="0" id="xdx_89D_ecustom--ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock_zN55WsDXEShe" style="font: 10.5pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 6)"&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span id="xdx_8B4_zaAFre5XkJXj" style="display: none"&gt;Schedule of weighted average assumptions for fair value of each option award&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2022&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Risk-free
interest rate&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_pip0_dp_c20221001__20230930_zKO6cup4Qeu1" title="Risk-free interest rate"&gt;3.70&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_pip0_dp_c20211001__20220930_zHZHxDG4efy4" title="Risk-free interest rate"&gt;3.11&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_909_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_pip0_dp_c20201001__20210930_zT78UQ0afMp7" title="Risk-free interest rate"&gt;0.73&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Expected
life of options (years)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90F_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_dtY_c20221001__20230930_zQgzQUIlWFjg" title="Expected life of options (years)"&gt;5.64&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_908_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_dtY_c20211001__20220930_zMxT0K2f40o5" title="Expected life of options (years)"&gt;5.57&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_901_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_dtY_c20201001__20210930_zfLzebHEUPni" title="Expected life of options (years)"&gt;5.74&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Annualized
volatility&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_pip0_dp_c20221001__20230930_z5WfFe3kdgzj" title="Annualized volatility"&gt;85.13&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_pip0_dp_c20211001__20220930_zAKopGanU2f2" title="Annualized volatility"&gt;84.17&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_904_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_pip0_dp_c20201001__20210930_zQ9PnpHPDlV2" title="Annualized volatility"&gt;93.43&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Dividend
rate&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_pip0_dp_c20221001__20230930_zQJP91L18KX4" title="Dividend rate"&gt;0.00&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_909_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_pip0_dp_c20211001__20220930_z2gilqQmyEg5" title="Dividend rate"&gt;0.00&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_pip0_dp_c20201001__20210930_z90iEDkkPtbe" title="Dividend rate"&gt;0.00&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;



&lt;p id="xdx_8A2_zyMT6BsApCPj" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
fair value of stock compensation charges recognized during the years ended September 30, 2023, 2022 and 2021 was determined with reference
to the quoted market price of the Company&#x2019;s shares on the grant date.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;















&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font: 10pt Times New Roman, Times, Serif"&gt;&lt;/span&gt;&lt;/p&gt;


</us-gaap:CommitmentsDisclosureTextBlock>
    <us-gaap:OperatingLeaseWeightedAverageRemainingLeaseTerm1 contextRef="AsOf2023-09-30">P12M</us-gaap:OperatingLeaseWeightedAverageRemainingLeaseTerm1>
    <us-gaap:LeaseCostTableTextBlock contextRef="From2022-10-01to2023-09-30">&lt;table cellpadding="0" cellspacing="0" id="xdx_892_eus-gaap--LeaseCostTableTextBlock_pn3n3_zebQe0HUsBil" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse" summary="xdx: Disclosure - Commitments and Contingencies (Details)"&gt;
  &lt;tr style="vertical-align: bottom"&gt;
    &lt;td style="text-align: left"&gt;&lt;span id="xdx_8BD_zRdYsDhim6L" style="display: none"&gt;Schedule of operating lease costs&lt;/span&gt;&lt;/td&gt;
    &lt;td&gt;&#160;&lt;/td&gt;
    &lt;td colspan="3" id="xdx_497_20221001__20230930_zoFz6uIyoz5h" style="text-align: center"&gt;&#160;&lt;/td&gt;
    &lt;td&gt;&#160;&lt;/td&gt;
    &lt;td colspan="3" id="xdx_497_20211001__20220930_zWLZSQljBpKc" style="text-align: center"&gt;&#160;&lt;/td&gt;
    &lt;td&gt;&#160;&lt;/td&gt;
    &lt;td colspan="3" id="xdx_496_20201001__20210930_zMlBeHRgn1ej" style="text-align: center"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
    &lt;td style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="11" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;September
    30,&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
  &lt;tr style="vertical-align: bottom"&gt;
    &lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;2023&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;2022&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;2021&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
  &lt;tr id="xdx_400_eus-gaap--OperatingLeaseCost_zNr7fwUnSpa" style="vertical-align: bottom; background-color: #CCEEFF"&gt;
    &lt;td style="width: 55%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Operating lease costs&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;118&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;73&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;$&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;131&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
  &lt;/table&gt;

</us-gaap:LeaseCostTableTextBlock>
    <us-gaap:OperatingLeaseCost
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">118000</us-gaap:OperatingLeaseCost>
    <us-gaap:OperatingLeaseCost
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">73000</us-gaap:OperatingLeaseCost>
    <us-gaap:OperatingLeaseCost
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">131000</us-gaap:OperatingLeaseCost>
    <us-gaap:DefinedContributionPlanDisclosuresTableTextBlock contextRef="From2022-10-01to2023-09-30">&lt;table cellpadding="0" cellspacing="0" id="xdx_89F_eus-gaap--DefinedContributionPlanDisclosuresTableTextBlock_pn3n3_z6GAoPcUR2E" style="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse" summary="xdx: Disclosure - Commitments and Contingencies (Details 1)"&gt;
  &lt;tr style="vertical-align: bottom"&gt;
    &lt;td style="text-align: left"&gt;&lt;span id="xdx_8B6_zNZ0ix4JlNLb" style="display: none"&gt;Schedule of contributions under the  plan&lt;/span&gt;&lt;/td&gt;
    &lt;td&gt;&#160;&lt;/td&gt;
    &lt;td colspan="3" id="xdx_497_20221001__20230930_zA0qushBeCO8" style="text-align: center"&gt;&#160;&lt;/td&gt;
    &lt;td&gt;&#160;&lt;/td&gt;
    &lt;td colspan="3" id="xdx_497_20211001__20220930_zj5JX4iHu8rg" style="text-align: center"&gt;&#160;&lt;/td&gt;
    &lt;td&gt;&#160;&lt;/td&gt;
    &lt;td colspan="3" id="xdx_496_20201001__20210930_zJ6NvaX8QTVe" style="text-align: center"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
    &lt;td style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="11" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;September
    30,&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
  &lt;tr style="vertical-align: bottom"&gt;
    &lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;2023&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;2022&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;
    &lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;2021&lt;/b&gt;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
  &lt;tr id="xdx_40C_eus-gaap--PensionContributions_zAjEbuXkDcDj" style="vertical-align: bottom; background-color: #CCEEFF"&gt;
    &lt;td style="width: 55%"&gt;&lt;p style="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Contributions
                           to 401(k) plan&lt;/span&gt;&lt;/p&gt;&lt;/td&gt;
    &lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;232&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;158&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;$&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;129&lt;/span&gt;&lt;/td&gt;
    &lt;td style="width: 1%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
  &lt;/table&gt;
&lt;p style="font: 9pt Sans-Serif; margin: 0; color: Red"&gt;&lt;/p&gt;

</us-gaap:DefinedContributionPlanDisclosuresTableTextBlock>
    <us-gaap:PensionContributions
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">232000</us-gaap:PensionContributions>
    <us-gaap:PensionContributions
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">158000</us-gaap:PensionContributions>
    <us-gaap:PensionContributions
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">129000</us-gaap:PensionContributions>
    <us-gaap:ClassOfWarrantOrRightOutstanding contextRef="AsOf2023-09-30" decimals="INF" unitRef="Shares">160000</us-gaap:ClassOfWarrantOrRightOutstanding>
    <us-gaap:ClassOfWarrantOrRightOutstanding contextRef="AsOf2022-09-30" decimals="INF" unitRef="Shares">160000</us-gaap:ClassOfWarrantOrRightOutstanding>
    <avxl:WarrantsOutstandingWeightedAverageExercise
      contextRef="AsOf2023-09-30"
      decimals="INF"
      unitRef="USDPShares">3.72</avxl:WarrantsOutstandingWeightedAverageExercise>
    <avxl:WarrantsOutstandingWeightedAverageExercise
      contextRef="AsOf2022-09-30"
      decimals="INF"
      unitRef="USDPShares">3.72</avxl:WarrantsOutstandingWeightedAverageExercise>
    <avxl:ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock contextRef="From2022-10-01to2023-09-30">&lt;table cellpadding="0" cellspacing="0" id="xdx_89E_ecustom--ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock_zKmN5o46PFt7" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 2)"&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="3" style="text-align: left"&gt;&lt;span id="xdx_8B6_zdQIUyosHM7i" style="display: none"&gt;Schedule of share purchase warrants outstanding&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Number&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: center; padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Exercise Price&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: center; padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Expiry Date&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants1Member_z7DIAed1ljy5" style="width: 26%; text-align: right" title="Number of warrants outstanding"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;150,000&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 8%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants1Member_zSEBrQgKsBAa" style="width: 26%; text-align: right" title="Exercise Price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3.17&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 8%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 26%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_906_eus-gaap--WarrantsAndRightsOutstandingMaturityDate_iI_dd_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants1Member_z4XXQCR7NqKd" title="Expiry Date"&gt;May 6, 2024&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants2Member_zek8ir0OxIK2" style="border-bottom: Black 1pt solid; text-align: right" title="Number of warrants outstanding"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;10,000&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants2Member_zckHC5eaRJ0f" style="border-bottom: Black 1pt solid; text-align: right" title="Exercise Price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;12.00&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_903_eus-gaap--WarrantsAndRightsOutstandingMaturityDate_iI_dd_c20230930__us-gaap--AwardTypeAxis__custom--PurchaseWarrants2Member_zCjIeYOFUu0j" title="Expiry Date"&gt;April 21, 2026&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_iI_pip0_c20230930_z1GBMONfXrj9" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of warrants outstanding"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;160,000&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; font-family: Times New Roman, Times, Serif; text-align: right"&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-family: Times New Roman, Times, Serif; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font: 12pt Times New Roman, Times, Serif; padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font: 12pt Times New Roman, Times, Serif; padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; font: 12pt Times New Roman, Times, Serif; text-align: right"&gt;&lt;/td&gt;
&lt;td style="font: 12pt Times New Roman, Times, Serif; padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;



</avxl:ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber
      contextRef="AsOf2023-09-30_custom_PurchaseWarrants1Member"
      decimals="INF"
      unitRef="Shares">150000</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_custom_PurchaseWarrants1Member"
      decimals="INF"
      unitRef="USDPShares">3.17</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice>
    <us-gaap:WarrantsAndRightsOutstandingMaturityDate contextRef="AsOf2023-09-30_custom_PurchaseWarrants1Member">2024-05-06</us-gaap:WarrantsAndRightsOutstandingMaturityDate>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber
      contextRef="AsOf2023-09-30_custom_PurchaseWarrants2Member"
      decimals="INF"
      unitRef="Shares">10000</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_custom_PurchaseWarrants2Member"
      decimals="INF"
      unitRef="USDPShares">12.00</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice>
    <us-gaap:WarrantsAndRightsOutstandingMaturityDate contextRef="AsOf2023-09-30_custom_PurchaseWarrants2Member">2026-04-21</us-gaap:WarrantsAndRightsOutstandingMaturityDate>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber contextRef="AsOf2023-09-30" decimals="INF" unitRef="Shares">160000</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber>
    <us-gaap:CommonStockCapitalSharesReservedForFutureIssuance
      contextRef="AsOf2023-09-30_custom_StockOptionPlan2015Member"
      decimals="INF"
      unitRef="Shares">6050553</us-gaap:CommonStockCapitalSharesReservedForFutureIssuance>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized
      contextRef="From2022-10-012023-09-30_custom_StockOptionPlan2019Member"
      decimals="INF"
      unitRef="Shares">6000000</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod
      contextRef="From2021-10-012022-09-30_custom_StockOptionPlan2022Member"
      decimals="INF"
      unitRef="Shares">406453</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized
      contextRef="From2022-03-242022-03-25_custom_StockOptionPlan2022Member"
      decimals="INF"
      unitRef="Shares">10000000</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized>
    <avxl:OptionIssued
      contextRef="From2022-10-01to2023-09-30"
      decimals="INF"
      unitRef="Shares">3849917</avxl:OptionIssued>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant
      contextRef="AsOf2023-09-30_custom_StockOptionPlan2022Member"
      decimals="INF"
      unitRef="Shares">6661535</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant>
    <us-gaap:ScheduleOfStockOptionsRollForwardTableTextBlock contextRef="From2022-10-01to2023-09-30">&lt;table cellpadding="0" cellspacing="0" id="xdx_890_eus-gaap--ScheduleOfStockOptionsRollForwardTableTextBlock_zahdwjh2ktsa" style="font: 9.5pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 3)"&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span id="xdx_8B4_zBRZ0wob6U9d" style="display: none"&gt;Schedule of stock option activity&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Weighted&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Weighted Average&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Average Grant&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Aggregate intrinsic&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Number of&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Exercise Price&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Date Fair Value&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;value&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Options&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;($)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;($)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;($)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; width: 18%; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Outstanding,
September 30, 2021&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 3%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iS_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zaQEDt8Geqwg" style="width: 16%; text-align: right" title="Number of options, Outstanding beginning balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;11,330,903&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 3%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iS_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zvh9J0z6rNSg" style="width: 16%; text-align: right" title="Weighted average exercise price, Outstanding beginning balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5.74&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 3%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_iS_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zm8JuTSr9WZg" style="width: 15%; text-align: right" title="Weighted average grant date fair value, Outstanding beginning balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl0768"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 3%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_iS_pp0p0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zMVx9451Ez4i" style="width: 15%; text-align: right" title="Aggregate intrinsic value, Outstanding beginning balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;140,132,451&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Granted&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zYDHLx1xNqd" style="text-align: right" title="Number of options, Granted"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,358,000&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_za6WMoclHJt6" style="text-align: right" title="Weighted average exercise price, Granted"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;10.13&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z12ur8IugGNa" style="text-align: right" title="Weighted average grant date fair value, Granted"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;7.07&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Forfeited&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_iN_pip0_di_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zzqgqYLwD0x8" style="text-align: right" title="Number of options, Forfeited"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(118,750&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98F_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zz0JNU8yhYOi" style="text-align: right" title="Weighted average exercise price, Forfeited"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;6.86&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_980_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zd5Dfy6k0HWb" style="text-align: right" title="Weighted average grant date fair value, Forfeited"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5.23&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Exercised&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--StockIssuedDuringPeriodSharesStockOptionsExercised_iN_pip0_di_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zLVBhCdfo3v2" style="border-bottom: Black 1pt solid; text-align: right" title="Number of options, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(400,537&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zNtv4tKDm84l" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2.52&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice_pip0_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zyXGXeuunFo" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average grant date fair value, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1.88&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_c20211001__20220930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_pp0p0" style="border-bottom: Black 1pt solid; text-align: right" title="Aggregate intrinsic value, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;4,201,015&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Outstanding,
September 30, 2022&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_983_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iS_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zF1F2l3FFbvl" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of options, Outstanding beginning balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;13,169,616&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iS_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zDoB5pRDMJR8" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price, Outstanding beginning balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;6.61&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; color: white; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_985_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_iS_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zP01qsGKaijj" style="border-bottom: Black 2.5pt double; font: normal 10pt Times New Roman, Times, Serif; text-align: right" title="Weighted average grant date fair value, Outstanding beginning balance"&gt;&lt;span style="font: normal 10pt Times New Roman, Times, Serif"&gt;4.96&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; color: white; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_iS_pp0p0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zoFSMXIeupJ3" style="border-bottom: Black 2.5pt double; text-align: right" title="Aggregate intrinsic value, Outstanding beginning balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;62,267,309&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Granted&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zdGzYZ6nAJ19" style="text-align: right" title="Number of options, Granted"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,959,000&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zZhiagjQKbJd" style="text-align: right" title="Weighted average exercise price, Granted"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;9.30&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_985_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_ziClWNBA0fig" style="text-align: right" title="Weighted average grant date fair value, Granted"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;6.60&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Expired&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Exercised&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_981_eus-gaap--StockIssuedDuringPeriodSharesStockOptionsExercised_iN_pip0_di_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zlKT4O9ITNx2" style="text-align: right" title="Number of options, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(759,753&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zjRxv8zRZ3s6" style="text-align: right" title="Weighted average exercise price, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2.34&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_987_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z3bIctfsRpu9" style="text-align: right" title="Weighted average grant date fair value, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;0.95&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_983_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_pp0p0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zumLJJKYvL95" style="text-align: right" title="Aggregate intrinsic value, Exercised"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;4,629,026&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Forfeited&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_985_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_iN_pip0_di_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zcgXAyqtdxn7" style="text-align: right" title="Number of options, Forfeited"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(257,083&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z189xmJSdqYh" style="text-align: right" title="Weighted average exercise price, Forfeited"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;12.00&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98E_ecustom--ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zPz67mlunnO8" style="text-align: right" title="Weighted average grant date fair value, Forfeited"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;6.74&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Cancelled&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Outstanding,
September 30, 2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iE_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zwxfgYOA6xzc" style="border-bottom: Black 1pt solid; text-align: right" title="Number of options, Outstanding ending balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;14,111,780&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iE_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zDKIrfhkqrwi" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price, Outstanding ending balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;7.12&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; color: white; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_iE_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z8QNfw1Q0kMg" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average grant date fair value,  Outstanding ending balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5.27&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; color: white; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_iE_pp0p0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zevpgIbVICHg" style="border-bottom: Black 1pt solid; text-align: right" title="Aggregate intrinsic value, Outstanding ending balance"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;22,290,069&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Exercisable,
September 30, 2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zJW8NDpTVbOa" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of options, Exercisable"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;9,604,614&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zhq3b5hS8iE" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price, Exercisable"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5.19&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; color: white"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; color: white; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_z7ZLBQG8DOQ9" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average grant date fair value, Exercisable"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3.94&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; color: white; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_iI_pp0p0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zde5865tfxlf" style="border-bottom: Black 2.5pt double; text-align: right" title="Aggregate intrinsic value, Exercisable"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;22,290,069&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;



</us-gaap:ScheduleOfStockOptionsRollForwardTableTextBlock>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
      contextRef="AsOf2021-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="Shares">11330903</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
      contextRef="AsOf2021-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">5.74</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
      contextRef="AsOf2021-09-30_us-gaap_StockOptionMember"
      decimals="0"
      unitRef="USD">140132451</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
      contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="Shares">2358000</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross>
    <us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
      contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">10.13</us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
      contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">7.07</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod
      contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="Shares">118750</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod>
    <us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice
      contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">6.86</us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice>
    <avxl:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice
      contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">5.23</avxl:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice>
    <us-gaap:StockIssuedDuringPeriodSharesStockOptionsExercised
      contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="Shares">400537</us-gaap:StockIssuedDuringPeriodSharesStockOptionsExercised>
    <us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
      contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">2.52</us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice>
    <avxl:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice
      contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">1.88</avxl:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
      contextRef="From2021-10-012022-09-30_us-gaap_StockOptionMember"
      decimals="0"
      unitRef="USD">4201015</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
      contextRef="AsOf2022-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="Shares">13169616</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
      contextRef="AsOf2022-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">6.61</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
      contextRef="AsOf2022-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">4.96</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
      contextRef="AsOf2022-09-30_us-gaap_StockOptionMember"
      decimals="0"
      unitRef="USD">62267309</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="Shares">1959000</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross>
    <us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">9.30</us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">6.60</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue>
    <us-gaap:StockIssuedDuringPeriodSharesStockOptionsExercised
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="Shares">759753</us-gaap:StockIssuedDuringPeriodSharesStockOptionsExercised>
    <us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">2.34</us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice>
    <avxl:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">0.95</avxl:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember"
      decimals="0"
      unitRef="USD">4629026</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="Shares">257083</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod>
    <us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">12.00</us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice>
    <avxl:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">6.74</avxl:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="Shares">14111780</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">7.12</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">5.27</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember"
      decimals="0"
      unitRef="USD">22290069</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="Shares">9604614</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">5.19</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">3.94</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember"
      decimals="0"
      unitRef="USD">22290069</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1>
    <us-gaap:ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock contextRef="From2022-10-01to2023-09-30">&lt;table cellpadding="0" cellspacing="0" id="xdx_89A_eus-gaap--ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_zEoDtaKA8WQ4" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 4)"&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: left"&gt;&lt;span id="xdx_8B5_zZ1azt0WqCG3" style="display: none"&gt;Schedule of summarizes information about stock options&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Weighted&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;average&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Weighted&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Number of&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;remaining&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;average&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Weighted&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="7" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Range of exercises
prices&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;outstanding&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;contractual&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;exercise&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Number of&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;average&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;From&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;To&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;options&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;life&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;price&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;vested options&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;exercise price&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_985_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zJYXBWgUxKda" style="width: 11%; text-align: right" title="Range of exercise prices, Lower range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;0.92&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_980_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_znfdhmj2ADy3" style="width: 11%; text-align: right" title="Range of exercise prices, Upper range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3.00&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zik41maNOF0h" style="width: 11%; text-align: right" title="Number of outstanding options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3,280,309&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_903_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zOoekuBKWZEa" title="Weighted average remaining contractual life"&gt;4.74&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zJmshsBbEIab" style="width: 10%; text-align: right" title="Weighted average exercise price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2.39&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_987_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_zbnUPrIBpwV2" style="width: 10%; text-align: right" title="Number of vested options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3,280,309&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 2%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_980_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice1Member_z9mbrl6XrXf" style="width: 10%; text-align: right" title="Weighted average exercise price options vested"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2.39&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_986_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_z7Y8nycQuh9a" style="text-align: right" title="Range of exercise prices, Lower range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3.01&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98B_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_z086mh1eEJ4h" style="text-align: right" title="Range of exercise prices, Upper range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5.00&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zWp1gnuPFd1h" style="text-align: right" title="Number of outstanding options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,017,500&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90D_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zfpbf6GJ6g7c" title="Weighted average remaining contractual life"&gt;4.32&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zCMjYCjifoc" style="text-align: right" title="Weighted average exercise price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3.28&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_zw5cQQ4bQl4a" style="text-align: right" title="Number of vested options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,017,500&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice2Member_ze2Cbpm9tHh3" style="text-align: right" title="Weighted average exercise price options vested"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3.28&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zfnYJas5hHn5" style="text-align: right" title="Range of exercise prices, Lower range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5.01&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_985_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zjw2rHU2tdde" style="text-align: right" title="Range of exercise prices, Upper range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;9.00&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zJwiUtbGVNFa" style="text-align: right" title="Number of outstanding options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5,260,054&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_903_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zv4ZErt5pUja" title="Weighted average remaining contractual life"&gt;6.21&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98A_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zAumZywNL2Bk" style="text-align: right" title="Weighted average exercise price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;6.90&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zKxXBt473Zje" style="text-align: right" title="Number of vested options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3,304,137&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice3Member_zr1Kzn0lL1M5" style="text-align: right" title="Weighted average exercise price options vested"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;6.10&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_982_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zLMY1YARIpUe" style="text-align: right" title="Range of exercise prices, Lower range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;9.01&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_984_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_z4hniAZlE363" style="text-align: right" title="Range of exercise prices, Upper range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;13.00&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zJdUNRWEL8Ql" style="text-align: right" title="Number of outstanding options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,981,917&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90D_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zVADhDSFa35f" title="Weighted average remaining contractual life"&gt;8.37&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_z7Spxmdt2g87" style="text-align: right" title="Weighted average exercise price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;10.55&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_980_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zm06iu99nx94" style="text-align: right" title="Number of vested options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;480,584&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_981_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice4Member_zVXTV9kNNHI3" style="text-align: right" title="Weighted average exercise price options vested"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;11.45&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zMWFZE1Vdnyc" style="text-align: right" title="Range of exercise prices, Lower range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;13.01&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zoLuZjUZdnX4" style="text-align: right" title="Range of exercise prices, Upper range limit"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;25.00&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_z8NHOEOWSvB9" style="border-bottom: Black 1pt solid; text-align: right" title="Number of outstanding options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,572,000&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90C_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zLQK7QouAmE9" title="Weighted average remaining contractual life"&gt;7.49&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zTu44CHbESU8" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;18.29&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_982_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zekHKoPStc37" style="border-bottom: Black 1pt solid; text-align: right" title="Number of vested options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;522,084&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember__us-gaap--ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis__custom--OptionPrice5Member_zaAU3Mj6dCX1" style="border-bottom: Black 1pt solid; text-align: right" title="Weighted average exercise price options vested"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;18.57&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="font-size: 10pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt; text-align: right"&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-size: 10pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-size: 10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-size: 10pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-size: 10pt; text-align: right"&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; font-size: 10pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_984_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zt2AET0WMtzk" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of outstanding options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;14,111,780&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90B_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_dtY_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zrvSy6PHWlcg" title="Weighted average remaining contractual life"&gt;6.04&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_986_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zz5zxf8fZNo8" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;7.12&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_984_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_pip0_c20221001__20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zQ4zwY5uofia" style="border-bottom: Black 2.5pt double; text-align: right" title="Number of vested options"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;9,604,614&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_982_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_iI_pip0_c20230930__us-gaap--DerivativeInstrumentRiskAxis__us-gaap--StockOptionMember_zvNCPuWNKxpi" style="border-bottom: Black 2.5pt double; text-align: right" title="Weighted average exercise price options vested"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5.19&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;



</us-gaap:ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock>
    <us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member"
      decimals="INF"
      unitRef="USDPShares">0.92</us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit>
    <us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member"
      decimals="INF"
      unitRef="USDPShares">3.00</us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member"
      decimals="INF"
      unitRef="Shares">3280309</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2 contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member">P4Y8M26D</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member"
      decimals="INF"
      unitRef="USDPShares">2.39</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member"
      decimals="INF"
      unitRef="Shares">3280309</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice1Member"
      decimals="INF"
      unitRef="USDPShares">2.39</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice>
    <us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member"
      decimals="INF"
      unitRef="USDPShares">3.01</us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit>
    <us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member"
      decimals="INF"
      unitRef="USDPShares">5.00</us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member"
      decimals="INF"
      unitRef="Shares">2017500</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2 contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member">P4Y3M25D</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member"
      decimals="INF"
      unitRef="USDPShares">3.28</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member"
      decimals="INF"
      unitRef="Shares">2017500</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice2Member"
      decimals="INF"
      unitRef="USDPShares">3.28</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice>
    <us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member"
      decimals="INF"
      unitRef="USDPShares">5.01</us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit>
    <us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member"
      decimals="INF"
      unitRef="USDPShares">9.00</us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member"
      decimals="INF"
      unitRef="Shares">5260054</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2 contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member">P6Y2M15D</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member"
      decimals="INF"
      unitRef="USDPShares">6.90</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member"
      decimals="INF"
      unitRef="Shares">3304137</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice3Member"
      decimals="INF"
      unitRef="USDPShares">6.10</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice>
    <us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member"
      decimals="INF"
      unitRef="USDPShares">9.01</us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit>
    <us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member"
      decimals="INF"
      unitRef="USDPShares">13.00</us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member"
      decimals="INF"
      unitRef="Shares">1981917</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2 contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member">P8Y4M13D</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member"
      decimals="INF"
      unitRef="USDPShares">10.55</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member"
      decimals="INF"
      unitRef="Shares">480584</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice4Member"
      decimals="INF"
      unitRef="USDPShares">11.45</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice>
    <us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member"
      decimals="INF"
      unitRef="USDPShares">13.01</us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit>
    <us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member"
      decimals="INF"
      unitRef="USDPShares">25.00</us-gaap:ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member"
      decimals="INF"
      unitRef="Shares">1572000</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2 contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member">P7Y5M26D</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member"
      decimals="INF"
      unitRef="USDPShares">18.29</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member"
      decimals="INF"
      unitRef="Shares">522084</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember_custom_OptionPrice5Member"
      decimals="INF"
      unitRef="USDPShares">18.57</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="Shares">14111780</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2 contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember">P6Y14D</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">7.12</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares
      contextRef="From2022-10-012023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="Shares">9604614</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice
      contextRef="AsOf2023-09-30_us-gaap_StockOptionMember"
      decimals="INF"
      unitRef="USDPShares">5.19</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue
      contextRef="From2022-10-01to2023-09-30"
      decimals="INF"
      unitRef="USDPShares">3.94</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue
      contextRef="From2021-10-012022-09-30"
      decimals="INF"
      unitRef="USDPShares">4.69</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue
      contextRef="From2020-10-012021-09-30"
      decimals="INF"
      unitRef="USDPShares">2.54</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2 contextRef="From2022-10-01to2023-09-30">P6Y</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2 contextRef="From2021-10-012022-09-30">P6Y4M24D</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2>
    <us-gaap:SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2 contextRef="From2022-10-01to2023-09-30">P4Y9M</us-gaap:SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2>
    <us-gaap:SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2 contextRef="From2021-10-012022-09-30">P5Y1M6D</us-gaap:SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2>
    <us-gaap:AllocatedShareBasedCompensationExpense
      contextRef="From2022-10-01to2023-09-30"
      decimals="-5"
      unitRef="USD">16400000</us-gaap:AllocatedShareBasedCompensationExpense>
    <us-gaap:AllocatedShareBasedCompensationExpense
      contextRef="From2021-10-012022-09-30"
      decimals="-5"
      unitRef="USD">18400000</us-gaap:AllocatedShareBasedCompensationExpense>
    <us-gaap:AllocatedShareBasedCompensationExpense
      contextRef="From2020-10-012021-09-30"
      decimals="-5"
      unitRef="USD">8200000</us-gaap:AllocatedShareBasedCompensationExpense>
    <us-gaap:ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock contextRef="From2022-10-01to2023-09-30">&lt;table cellpadding="0" cellspacing="0" id="xdx_893_eus-gaap--ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_pn3n3_zi05WuRK54V9" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 5)"&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span id="xdx_8B0_zVkn5OI5YY12" style="display: none"&gt;Schedule of general and administrative expenses and research and development expenses&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="11" style="font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;September
30,&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2022&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; font-family: Times New Roman, Times, Serif; font-weight: bold"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; font-family: Times New Roman, Times, Serif; font-weight: bold; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;General
and administrative&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98A_eus-gaap--ShareBasedCompensation_pn3n3_c20221001__20230930__us-gaap--IncomeStatementLocationAxis__us-gaap--GeneralAndAdministrativeExpenseMember_zlegHFiNw3u9" style="width: 11%; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;5,558&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--ShareBasedCompensation_pn3n3_c20211001__20220930__us-gaap--IncomeStatementLocationAxis__us-gaap--GeneralAndAdministrativeExpenseMember_zt8VbpPKl4ri" style="width: 11%; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;7,129&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_989_eus-gaap--ShareBasedCompensation_pn3n3_c20201001__20210930__us-gaap--IncomeStatementLocationAxis__us-gaap--GeneralAndAdministrativeExpenseMember_ztXzYhbjPTtj" style="width: 11%; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3,571&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Research
and development&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_98E_eus-gaap--ShareBasedCompensation_pn3n3_c20221001__20230930__us-gaap--IncomeStatementLocationAxis__us-gaap--ResearchAndDevelopmentExpenseMember_zxlwTaY7roA2" style="border-bottom: Black 1pt solid; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;10,812&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_982_eus-gaap--ShareBasedCompensation_pn3n3_c20211001__20220930__us-gaap--IncomeStatementLocationAxis__us-gaap--ResearchAndDevelopmentExpenseMember_zMnF2RIYqYD7" style="border-bottom: Black 1pt solid; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;11,250&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_987_eus-gaap--ShareBasedCompensation_pn3n3_c20201001__20210930__us-gaap--IncomeStatementLocationAxis__us-gaap--ResearchAndDevelopmentExpenseMember_zbbLNUWHcCQk" style="border-bottom: Black 1pt solid; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;4,660&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Total
stock-based compensation&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_983_eus-gaap--ShareBasedCompensation_pn3n3_c20221001__20230930_zBefjtLfXJBl" style="border-bottom: Black 2.5pt double; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;16,370&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_985_eus-gaap--ShareBasedCompensation_pn3n3_c20211001__20220930_zJqVKJNEeNN2" style="border-bottom: Black 2.5pt double; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;18,379&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td id="xdx_988_eus-gaap--ShareBasedCompensation_pn3n3_c20201001__20210930_zNPDO6PYdgbh" style="border-bottom: Black 2.5pt double; text-align: right" title="Total share based compensation"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;8,231&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;



</us-gaap:ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock>
    <us-gaap:ShareBasedCompensation
      contextRef="From2022-10-012023-09-30_us-gaap_GeneralAndAdministrativeExpenseMember"
      decimals="-3"
      unitRef="USD">5558000</us-gaap:ShareBasedCompensation>
    <us-gaap:ShareBasedCompensation
      contextRef="From2021-10-012022-09-30_us-gaap_GeneralAndAdministrativeExpenseMember"
      decimals="-3"
      unitRef="USD">7129000</us-gaap:ShareBasedCompensation>
    <us-gaap:ShareBasedCompensation
      contextRef="From2020-10-012021-09-30_us-gaap_GeneralAndAdministrativeExpenseMember"
      decimals="-3"
      unitRef="USD">3571000</us-gaap:ShareBasedCompensation>
    <us-gaap:ShareBasedCompensation
      contextRef="From2022-10-012023-09-30_us-gaap_ResearchAndDevelopmentExpenseMember"
      decimals="-3"
      unitRef="USD">10812000</us-gaap:ShareBasedCompensation>
    <us-gaap:ShareBasedCompensation
      contextRef="From2021-10-012022-09-30_us-gaap_ResearchAndDevelopmentExpenseMember"
      decimals="-3"
      unitRef="USD">11250000</us-gaap:ShareBasedCompensation>
    <us-gaap:ShareBasedCompensation
      contextRef="From2020-10-012021-09-30_us-gaap_ResearchAndDevelopmentExpenseMember"
      decimals="-3"
      unitRef="USD">4660000</us-gaap:ShareBasedCompensation>
    <us-gaap:ShareBasedCompensation
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">16370000</us-gaap:ShareBasedCompensation>
    <us-gaap:ShareBasedCompensation
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">18379000</us-gaap:ShareBasedCompensation>
    <us-gaap:ShareBasedCompensation
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">8231000</us-gaap:ShareBasedCompensation>
    <us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions contextRef="AsOf2023-09-30" decimals="-5" unitRef="USD">14100000</us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions>
    <avxl:ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock contextRef="From2022-10-01to2023-09-30">&lt;table cellpadding="0" cellspacing="0" id="xdx_89D_ecustom--ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock_zN55WsDXEShe" style="font: 10.5pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Commitments and Contingencies (Details 6)"&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span id="xdx_8B4_zaAFre5XkJXj" style="display: none"&gt;Schedule of weighted average assumptions for fair value of each option award&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2022&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Risk-free
interest rate&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_pip0_dp_c20221001__20230930_zKO6cup4Qeu1" title="Risk-free interest rate"&gt;3.70&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_pip0_dp_c20211001__20220930_zHZHxDG4efy4" title="Risk-free interest rate"&gt;3.11&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_909_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_pip0_dp_c20201001__20210930_zT78UQ0afMp7" title="Risk-free interest rate"&gt;0.73&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Expected
life of options (years)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90F_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_dtY_c20221001__20230930_zQgzQUIlWFjg" title="Expected life of options (years)"&gt;5.64&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_908_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_dtY_c20211001__20220930_zMxT0K2f40o5" title="Expected life of options (years)"&gt;5.57&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_901_eus-gaap--SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_dtY_c20201001__20210930_zfLzebHEUPni" title="Expected life of options (years)"&gt;5.74&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Annualized
volatility&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_pip0_dp_c20221001__20230930_z5WfFe3kdgzj" title="Annualized volatility"&gt;85.13&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90C_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_pip0_dp_c20211001__20220930_zAKopGanU2f2" title="Annualized volatility"&gt;84.17&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_904_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_pip0_dp_c20201001__20210930_zQ9PnpHPDlV2" title="Annualized volatility"&gt;93.43&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Dividend
rate&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90D_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_pip0_dp_c20221001__20230930_zQJP91L18KX4" title="Dividend rate"&gt;0.00&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_909_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_pip0_dp_c20211001__20220930_z2gilqQmyEg5" title="Dividend rate"&gt;0.00&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span id="xdx_90E_eus-gaap--ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_pip0_dp_c20201001__20210930_z90iEDkkPtbe" title="Dividend rate"&gt;0.00&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;



</avxl:ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
      contextRef="From2022-10-01to2023-09-30"
      decimals="INF"
      unitRef="Pure">0.0370</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
      contextRef="From2021-10-012022-09-30"
      decimals="INF"
      unitRef="Pure">0.0311</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
      contextRef="From2020-10-012021-09-30"
      decimals="INF"
      unitRef="Pure">0.0073</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1 contextRef="From2022-10-01to2023-09-30">P5Y7M20D</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1 contextRef="From2021-10-012022-09-30">P5Y6M25D</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1>
    <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1 contextRef="From2020-10-012021-09-30">P5Y8M26D</us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
      contextRef="From2022-10-01to2023-09-30"
      decimals="INF"
      unitRef="Pure">0.8513</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
      contextRef="From2021-10-012022-09-30"
      decimals="INF"
      unitRef="Pure">0.8417</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
      contextRef="From2020-10-012021-09-30"
      decimals="INF"
      unitRef="Pure">0.9343</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
      contextRef="From2022-10-01to2023-09-30"
      decimals="INF"
      unitRef="Pure">0.0000</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
      contextRef="From2021-10-012022-09-30"
      decimals="INF"
      unitRef="Pure">0.0000</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate>
    <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
      contextRef="From2020-10-012021-09-30"
      decimals="INF"
      unitRef="Pure">0.0000</us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate>
    <us-gaap:IncomeTaxDisclosureTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_809_eus-gaap--IncomeTaxDisclosureTextBlock_zskvIWwUEx38" style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;Note
7	 	&lt;span id="xdx_82F_z9n0dvl8UTs4"&gt;Income Taxes&lt;/span&gt; &lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company&#x2019;s U.S. and foreign loss before income taxes are set forth below (in thousands):&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;table cellpadding="0" cellspacing="0" id="xdx_894_eus-gaap--ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock_pn3n3_z4sCfQjlSamk" style="font: 9.5pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Income Taxes (Details)"&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left"&gt;&lt;span id="xdx_8B0_zY6zjeyTPFke" style="display: none"&gt;Schedule of loss before
income taxes&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_496_20221001_20230930" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_494_20211001_20220930" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_492_20201001_20210930" style="text-align: center"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2022&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_408_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;United
States&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(41,198&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(40,002&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(28,851&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_406_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_zSoEJlgOqv97" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Foreign&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(6,300&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(7,618&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(8,790&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40A_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_z76oU3PPoFLf" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 2.5pt 10pt; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Total&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(47,498&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(47,620&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(37,641&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;



&lt;p id="xdx_8A6_znTzPaTwtQal" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
components of net deferred income tax assets as of September 30, 2023, 2022 and 2021 are as follows (in thousands):&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 12pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;/span&gt;&lt;/p&gt;

&lt;table cellpadding="0" cellspacing="0" id="xdx_893_eus-gaap--ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_pn3n3_z2nP6y5V9QFk" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Income Taxes (Details 1)"&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left"&gt;&lt;span id="xdx_8BF_zF3rKRkptpk8" style="display: none"&gt;Schedule of components of
net deferred income tax assets&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_49D_20230930" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_493_20220930" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_498_20210930_zaE4q2jgcLma" style="text-align: center"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2022&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40B_eus-gaap--DeferredTaxAssetsOperatingLossCarryforwards_iI_z9TlGYr5v4be" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Net
operating loss carryforwards&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;46,462&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;46,208&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;34,982&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_409_eus-gaap--DeferredTaxAssetsInProcessResearchAndDevelopment_iI_zEOjZKyH2Mn2" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Research
and development tax credit carryforwards&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,713&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,182&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,577&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_408_eus-gaap--DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_iI_zpUuEvXfHkF2" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Stock-based
compensation&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;18,593&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;13,373&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;10,453&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_407_ecustom--DeferredTaxAssetsResearchAndDevelopmentCapitalization_iI_zXJnEltE20u1" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Research
and development capitalization&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;7,219&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1029"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1030"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_408_ecustom--DeferredTaxAssetsUnpaidCharges_iI_zX2XoiNZ1rjk" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Unpaid
charges&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,559&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;894&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;89&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40A_eus-gaap--DeferredTaxAssetsGoodwillAndIntangibleAssets_iI_zQyMqOHHjd39" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Intangible
asset costs&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;593&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;388&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;323&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_403_eus-gaap--DeferredTaxAssetsUnrealizedCurrencyLosses_iI_zS92gCVLPkw" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Foreign
exchange and other&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;49&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;44&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;62&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40B_eus-gaap--DeferredTaxAssetsValuationAllowance_iNI_di_z51AqN69x9S5" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Valuation
allowance of deferred tax assets&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(77,188&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(63,089&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(47,486&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40E_eus-gaap--DeferredTaxAssetsNet_iI_zTZlhwMjO2M1" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Net
deferred tax assets&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1048"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1049"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1050"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;


&lt;p id="xdx_8A7_zl9mCbge1VK9" style="font: 12pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;A
reconciliation of income tax expense at the statutory federal income tax rate and income taxes as reflected in the consolidated financial
statements for the years ended September 30, 2023, 2022 and 2021 is as follows (in thousands):&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 12pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;/span&gt;&lt;/p&gt;

&lt;table cellpadding="0" cellspacing="0" id="xdx_89E_eus-gaap--ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_pn3n3_zsVzljCQ03c6" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Income Taxes (Details 2)"&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span id="xdx_8BA_z701s73Iniah" style="display: none"&gt;Schedule
of reconciliation of income tax expense&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_49C_20221001__20230930_z6poV6auzo5i" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_495_20211001__20220930_zgRuwYwJDgEf" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_493_20201001__20210930_zLPqPPjEels4" style="text-align: center"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2022&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40D_eus-gaap--IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_zRekekCgXmOh" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Income
tax benefit at statutory federal rate&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(9,975&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(10,000&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(7,934&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40C_eus-gaap--IncomeTaxReconciliationForeignIncomeTaxRateDifferential_ziOeNTMw5XHh" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Foreign
income taxed at other rates&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1058"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(170&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(353&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_408_ecustom--PermanentDifferencesRelatingToStockBasedCompensation_zMH8Yb6MSbN9" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Permanent
differences relating to stock based compensation&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(601&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(714&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(4,379&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40A_eus-gaap--EffectiveIncomeTaxRateReconciliationGiltiAmount_zuYDNTfabwmg" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Permanent
differences relating to GILTI inclusion&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;165&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1067"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1068"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_401_ecustom--PermanentDifferencesRelatingToSection162m_zopWtm3badqj" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Permanent
differences relating to Section 162(m)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1070"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1071"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;816&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40F_eus-gaap--IncomeTaxReconciliationOtherAdjustments_i_pp0p0" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Other
permanent differences&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;273&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1075"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;741&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_401_ecustom--AdjustmentToTaxAssetsBasedOnSection382_zAIrAcBONkAk" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Adjustment
to tax assets based on Section 382&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1078"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1079"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3,330&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_408_ecustom--IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet_zlsUXX2azvUd" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Research
and development credits, net&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(37&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;232&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,042&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_405_eus-gaap--IncomeTaxReconciliationStateAndLocalIncomeTaxes_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;State
and local taxes&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(4,122&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(4,975&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(7,022&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40C_eus-gaap--IncomeTaxReconciliationPriorYearIncomeTaxes_i_pp0p0" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Adjustment
to true up to prior years' tax provision&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;206&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;24&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;48&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40B_eus-gaap--IncomeTaxReconciliationChangeInEnactedTaxRate_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Effect
of change in statutory tax rates&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1094"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1095"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;216&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_408_eus-gaap--TaxesExcludingIncomeAndExciseTaxes_i_pp0p0" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;State
minimum and excise taxes&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1098"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;358&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;268&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40C_eus-gaap--IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Change
in valuation allowances&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;14,098&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;15,603&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;13,495&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_405_eus-gaap--DeferredIncomeTaxExpenseBenefit_i_pp0p0" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Income
tax expense&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;7&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;358&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;268&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;


&lt;p id="xdx_8A4_z3qn8d22c1X8" style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;
















&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;As
of September 30, 2023, the Company had U.S. federal net operating loss carryforwards of approximately $&lt;span id="xdx_90A_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20230930__us-gaap--IncomeTaxAuthorityAxis__custom--FederalMember_zosExQ9Ni2ve" title="Operating loss carryforwards"&gt;126.3&lt;/span&gt; million (2022: $&lt;span id="xdx_90A_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20220930__us-gaap--IncomeTaxAuthorityAxis__custom--FederalMember_znacYwgHTTK7" title="Operating loss carryforwards"&gt;123.4&lt;/span&gt; million)
of which &lt;span id="xdx_905_ecustom--OperatingLossCarryforwardsDescription_c20221001__20230930__us-gaap--IncomeTaxAuthorityAxis__custom--FederalMember_z90eQ9gTvLZ2" title="Operating loss carryforwards description"&gt;$37.7 million will begin to expire in 2025 and $88.6 million can be carried forward indefinitely&lt;/span&gt;, state and local net operating
loss carryforwards of approximately $ &lt;span id="xdx_90C_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20230930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--StateAndLocalJurisdictionMember_znWgRNUdAPJi" title="Operating loss carryforwards"&gt;16.6&lt;/span&gt; million (2022: $&lt;span id="xdx_903_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20220930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--StateAndLocalJurisdictionMember_zkKt1osnqZF" title="Operating loss carryforwards"&gt;17.2&lt;/span&gt; million) which will begin to expire in &lt;span id="xdx_900_ecustom--OperatingLossCarryForwardsExpirationYear_c20221001__20230930_zdJ60uniXWnf" title="Operating loss carry forwards expiration year"&gt;2036&lt;/span&gt;, and Research and Development
tax credits of approximately $&lt;span id="xdx_90E_eus-gaap--IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment_pn5n6_c20221001__20230930_zQ2xyYUFqcF4" title="Research and Development tax credits"&gt;2.7&lt;/span&gt; million (2022: $&lt;span id="xdx_90E_eus-gaap--IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment_pn5n6_c20211001__20220930_zwbv1IZxF4yf" title="Research and Development tax credits"&gt;2.2&lt;/span&gt; million) which will begin to expire in &lt;span id="xdx_901_ecustom--ResearchAndDevelopmentTaxCreditsYear_c20221001__20230930_z37rCamF6FZf" title="Research and development tax credits year"&gt;2029&lt;/span&gt;. The Company had approximately $&lt;span id="xdx_908_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20230930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--ForeignCountryMember_zqR1kpkjOcZi" title="Operating loss carryforwards"&gt;12.9&lt;/span&gt;
million (approximately AU$&lt;span id="xdx_90C_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20230930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--ForeignCountryMember__srt--CurrencyAxis__currency--AUD_ztNLboBVPHeh" title="Operating loss carryforwards"&gt;20.1&lt;/span&gt; million) (2022: $&lt;span id="xdx_909_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20220930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--ForeignCountryMember_ziNKvWRETWKa" title="Operating loss carryforwards"&gt;10.6&lt;/span&gt; million (approximately AU$ &lt;span id="xdx_90A_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20220930__us-gaap--IncomeTaxAuthorityAxis__us-gaap--ForeignCountryMember__srt--CurrencyAxis__currency--AUD_zPtmb3CPEkbk" title="Operating loss carryforwards"&gt;14.9&lt;/span&gt; million)) of net operating loss carryforwards in
Australia, which have an indefinite life, available to offset future taxable income in those jurisdictions.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;


&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company evaluates its valuation allowance requirements based on available evidence. When circumstances change, and this causes a change
in management&#x2019;s judgment about the recoverability of deferred tax assets, the impact of the change on the valuation allowance is
reflected in current income. Because management of the Company does not currently believe that it is more likely than not that the Company
will receive the benefit of these assets, a valuation allowance has been established at September 30, 2023 and 2022.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Tax Cuts and Jobs Act of 2017 (TCJA) has modified the IRC 174 expenses related to research and development for tax years beginning after
December 31, 2021. Under the TCJA, the Company must now capitalize the expenditures related to research and development activities and
amortize over five years for U.S. activities and 15 years for non-U.S. activities using a mid-year convention. Therefore, the capitalization
of research and development costs in accordance with IRC 174 resulted in a gross deferred tax asset of $&lt;span id="xdx_902_eus-gaap--DeferredTaxAssetsGross_iI_pn5n6_c20230930_z5Huz0MUkYf6" title="Gross deferred tax asset"&gt;7.2&lt;/span&gt; million.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Uncertain
Tax Positions&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company files income tax returns in the U.S. federal jurisdiction and various state and local and foreign jurisdictions. The Company&#x2019;s
tax returns are subject to tax examinations by U.S. federal and state tax authorities, or examinations by foreign tax authorities until
the respective statutes of limitation expire. The Company is subject to tax examinations by tax authorities for all taxation years commencing
on or after 2005.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Under
the provisions of the Internal Revenue Code, the net operating loss (&#x201c;NOL&#x201d;) carryforwards are subject to review and possible
adjustment by the Internal Revenue Service and state tax authorities. Under Section 382 of the Internal Revenue Code, NOL and tax credit
carryforwards may become subject to an annual limitation in the event of an over 50% cumulative change in the ownership interest of significant
stockholders over a three-year period, as well as similar state tax provisions.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company conducted a Section 382 study during the year ended September 30, 2021 and determined that, during the year ended September 30,
2015, there was a change in ownership which resulted in $&lt;span id="xdx_901_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20150930__us-gaap--IncomeTaxAuthorityAxis__custom--FederalMember_zuBVmpmXLoCf" title="Operating loss carryforwards"&gt;25.8&lt;/span&gt; million of federal NOLs being subject to an annual limitation. During the
year ended September 30, 2021, the Company reduced its federal NOLs by $&lt;span id="xdx_909_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20210930__us-gaap--IncomeTaxAuthorityAxis__custom--FederalMember_zoCzhr2kvOkb" title="Operating loss carryforwards"&gt;12.1&lt;/span&gt; million and its Research and Development tax credit carryforwards
by $&lt;span id="xdx_90F_eus-gaap--DeferredTaxAssetsTaxCreditCarryforwardsResearch_iI_pn5n6_c20210930_zkOU6AbJlz5e" title="Research and development tax credit carryforwards"&gt;0.8&lt;/span&gt; million, which are the amount of tax assets that will expire unutilized pursuant to the Section 382 study. This resulted in a
reduction of $&lt;span id="xdx_90C_eus-gaap--OperatingLossCarryforwards_iI_pn5n6_c20210930_zkk8l6wnAZm9" title="Operating loss carryforwards"&gt;2.5&lt;/span&gt; million of NOLs and $&lt;span id="xdx_90F_eus-gaap--DeferredTaxAssetsTaxCreditCarryforwardsResearch_iI_pn5n6_c20210930_zugz7EAgAHc8" title="Research and development tax credit carryforwards"&gt;0.8&lt;/span&gt; million of research and development credits and a corresponding reduction in the valuation
allowance of $&lt;span id="xdx_901_eus-gaap--ValuationAllowanceDeferredTaxAssetChangeInAmount_pn5n6_c20201001__20210930_zAPCM1FPnLya" title="Decrease in valuation allowance"&gt;3.3&lt;/span&gt; million, which was recorded in the 2021 fiscal year. Subsequent ownership changes in future years could trigger additional
limitations of the Company&#x2019;s NOLs&lt;span style="background-color: white"&gt;. During the year ended September 30, 2023 and 2022 the
Company determined that there were no changes in ownership pursuant to Section 382.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;As
of September 30, 2023, the Company did not provide any foreign withholding taxes related to its foreign subsidiaries&#x2019; undistributed
earnings, as such earnings have been retained and are intended to be indefinitely reinvested to fund ongoing operations of the foreign
subsidiaries. It is not practicable to estimate the amount of taxes that would be payable upon remittance of these earnings, because
such tax, if any, is dependent upon circumstances existing if and when remittance occur.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</us-gaap:IncomeTaxDisclosureTextBlock>
    <us-gaap:ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock contextRef="From2022-10-01to2023-09-30">&lt;table cellpadding="0" cellspacing="0" id="xdx_894_eus-gaap--ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock_pn3n3_z4sCfQjlSamk" style="font: 9.5pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Income Taxes (Details)"&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left"&gt;&lt;span id="xdx_8B0_zY6zjeyTPFke" style="display: none"&gt;Schedule of loss before
income taxes&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_496_20221001_20230930" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_494_20211001_20220930" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_492_20201001_20210930" style="text-align: center"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2022&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_408_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;United
States&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(41,198&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(40,002&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(28,851&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_406_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_zSoEJlgOqv97" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Foreign&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(6,300&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(7,618&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(8,790&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40A_eus-gaap--IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_z76oU3PPoFLf" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 2.5pt 10pt; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Total&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(47,498&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(47,620&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(37,641&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;



</us-gaap:ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-41198000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-40002000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-28851000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-6300000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-7618000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-8790000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-47498000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-47620000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-37641000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest>
    <us-gaap:ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock contextRef="From2022-10-01to2023-09-30">&lt;table cellpadding="0" cellspacing="0" id="xdx_893_eus-gaap--ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_pn3n3_z2nP6y5V9QFk" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Income Taxes (Details 1)"&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left"&gt;&lt;span id="xdx_8BF_zF3rKRkptpk8" style="display: none"&gt;Schedule of components of
net deferred income tax assets&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_49D_20230930" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_493_20220930" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_498_20210930_zaE4q2jgcLma" style="text-align: center"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2022&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40B_eus-gaap--DeferredTaxAssetsOperatingLossCarryforwards_iI_z9TlGYr5v4be" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Net
operating loss carryforwards&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;46,462&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;46,208&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;34,982&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_409_eus-gaap--DeferredTaxAssetsInProcessResearchAndDevelopment_iI_zEOjZKyH2Mn2" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Research
and development tax credit carryforwards&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,713&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2,182&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,577&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_408_eus-gaap--DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_iI_zpUuEvXfHkF2" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Stock-based
compensation&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;18,593&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;13,373&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;10,453&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_407_ecustom--DeferredTaxAssetsResearchAndDevelopmentCapitalization_iI_zXJnEltE20u1" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Research
and development capitalization&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;7,219&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1029"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1030"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_408_ecustom--DeferredTaxAssetsUnpaidCharges_iI_zX2XoiNZ1rjk" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Unpaid
charges&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,559&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;894&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;89&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40A_eus-gaap--DeferredTaxAssetsGoodwillAndIntangibleAssets_iI_zQyMqOHHjd39" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Intangible
asset costs&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;593&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;388&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;323&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_403_eus-gaap--DeferredTaxAssetsUnrealizedCurrencyLosses_iI_zS92gCVLPkw" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Foreign
exchange and other&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;49&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;44&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;62&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40B_eus-gaap--DeferredTaxAssetsValuationAllowance_iNI_di_z51AqN69x9S5" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Valuation
allowance of deferred tax assets&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(77,188&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(63,089&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(47,486&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40E_eus-gaap--DeferredTaxAssetsNet_iI_zTZlhwMjO2M1" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Net
deferred tax assets&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1048"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1049"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1050"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;


</us-gaap:ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock>
    <us-gaap:DeferredTaxAssetsOperatingLossCarryforwards contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">46462000</us-gaap:DeferredTaxAssetsOperatingLossCarryforwards>
    <us-gaap:DeferredTaxAssetsOperatingLossCarryforwards contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">46208000</us-gaap:DeferredTaxAssetsOperatingLossCarryforwards>
    <us-gaap:DeferredTaxAssetsOperatingLossCarryforwards contextRef="AsOf2021-09-30" decimals="-3" unitRef="USD">34982000</us-gaap:DeferredTaxAssetsOperatingLossCarryforwards>
    <us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">2713000</us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment>
    <us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">2182000</us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment>
    <us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment contextRef="AsOf2021-09-30" decimals="-3" unitRef="USD">1577000</us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment>
    <us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">18593000</us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost>
    <us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">13373000</us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost>
    <us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost contextRef="AsOf2021-09-30" decimals="-3" unitRef="USD">10453000</us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost>
    <avxl:DeferredTaxAssetsResearchAndDevelopmentCapitalization contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">7219000</avxl:DeferredTaxAssetsResearchAndDevelopmentCapitalization>
    <avxl:DeferredTaxAssetsUnpaidCharges contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">1559000</avxl:DeferredTaxAssetsUnpaidCharges>
    <avxl:DeferredTaxAssetsUnpaidCharges contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">894000</avxl:DeferredTaxAssetsUnpaidCharges>
    <avxl:DeferredTaxAssetsUnpaidCharges contextRef="AsOf2021-09-30" decimals="-3" unitRef="USD">89000</avxl:DeferredTaxAssetsUnpaidCharges>
    <us-gaap:DeferredTaxAssetsGoodwillAndIntangibleAssets contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">593000</us-gaap:DeferredTaxAssetsGoodwillAndIntangibleAssets>
    <us-gaap:DeferredTaxAssetsGoodwillAndIntangibleAssets contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">388000</us-gaap:DeferredTaxAssetsGoodwillAndIntangibleAssets>
    <us-gaap:DeferredTaxAssetsGoodwillAndIntangibleAssets contextRef="AsOf2021-09-30" decimals="-3" unitRef="USD">323000</us-gaap:DeferredTaxAssetsGoodwillAndIntangibleAssets>
    <us-gaap:DeferredTaxAssetsUnrealizedCurrencyLosses contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">49000</us-gaap:DeferredTaxAssetsUnrealizedCurrencyLosses>
    <us-gaap:DeferredTaxAssetsUnrealizedCurrencyLosses contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">44000</us-gaap:DeferredTaxAssetsUnrealizedCurrencyLosses>
    <us-gaap:DeferredTaxAssetsUnrealizedCurrencyLosses contextRef="AsOf2021-09-30" decimals="-3" unitRef="USD">62000</us-gaap:DeferredTaxAssetsUnrealizedCurrencyLosses>
    <us-gaap:DeferredTaxAssetsValuationAllowance contextRef="AsOf2023-09-30" decimals="-3" unitRef="USD">77188000</us-gaap:DeferredTaxAssetsValuationAllowance>
    <us-gaap:DeferredTaxAssetsValuationAllowance contextRef="AsOf2022-09-30" decimals="-3" unitRef="USD">63089000</us-gaap:DeferredTaxAssetsValuationAllowance>
    <us-gaap:DeferredTaxAssetsValuationAllowance contextRef="AsOf2021-09-30" decimals="-3" unitRef="USD">47486000</us-gaap:DeferredTaxAssetsValuationAllowance>
    <us-gaap:ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock contextRef="From2022-10-01to2023-09-30">&lt;table cellpadding="0" cellspacing="0" id="xdx_89E_eus-gaap--ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_pn3n3_zsVzljCQ03c6" style="font: 10pt Arial, Helvetica, Sans-Serif; border-collapse: collapse; width: 100%" summary="xdx: Disclosure - Income Taxes (Details 2)"&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding-top: 0pt; padding-right: 0pt; padding-left: 10pt; font-size: 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span id="xdx_8BA_z701s73Iniah" style="display: none"&gt;Schedule
of reconciliation of income tax expense&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_49C_20221001__20230930_z6poV6auzo5i" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_495_20211001__20220930_zgRuwYwJDgEf" style="text-align: center"&gt;&#160;&lt;/td&gt;
&lt;td&gt;&#160;&lt;/td&gt;
&lt;td colspan="3" id="xdx_493_20201001__20210930_zLPqPPjEels4" style="text-align: center"&gt;&#160;&lt;/td&gt;&lt;/tr&gt;
&lt;tr style="vertical-align: bottom"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; font-size: 10pt; text-align: center; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2023&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2022&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td colspan="3" style="border-bottom: Black 1pt solid; text-align: center"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40D_eus-gaap--IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_zRekekCgXmOh" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; width: 46%; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Income
tax benefit at statutory federal rate&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(9,975&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(10,000&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 5%"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 11%; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(7,934&lt;/span&gt;&lt;/td&gt;
&lt;td style="width: 1%; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40C_eus-gaap--IncomeTaxReconciliationForeignIncomeTaxRateDifferential_ziOeNTMw5XHh" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Foreign
income taxed at other rates&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1058"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(170&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(353&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_408_ecustom--PermanentDifferencesRelatingToStockBasedCompensation_zMH8Yb6MSbN9" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Permanent
differences relating to stock based compensation&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(601&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(714&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(4,379&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40A_eus-gaap--EffectiveIncomeTaxRateReconciliationGiltiAmount_zuYDNTfabwmg" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Permanent
differences relating to GILTI inclusion&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;165&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1067"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1068"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_401_ecustom--PermanentDifferencesRelatingToSection162m_zopWtm3badqj" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Permanent
differences relating to Section 162(m)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1070"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1071"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;816&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40F_eus-gaap--IncomeTaxReconciliationOtherAdjustments_i_pp0p0" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Other
permanent differences&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;273&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1075"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;741&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_401_ecustom--AdjustmentToTaxAssetsBasedOnSection382_zAIrAcBONkAk" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Adjustment
to tax assets based on Section 382&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1078"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1079"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;3,330&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_408_ecustom--IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet_zlsUXX2azvUd" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Research
and development credits, net&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(37&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;232&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;1,042&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_405_eus-gaap--IncomeTaxReconciliationStateAndLocalIncomeTaxes_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;State
and local taxes&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(4,122&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(4,975&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;(7,022&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;)&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40C_eus-gaap--IncomeTaxReconciliationPriorYearIncomeTaxes_i_pp0p0" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Adjustment
to true up to prior years' tax provision&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;206&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;24&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;48&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40B_eus-gaap--IncomeTaxReconciliationChangeInEnactedTaxRate_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Effect
of change in statutory tax rates&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1094"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1095"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;216&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_408_eus-gaap--TaxesExcludingIncomeAndExciseTaxes_i_pp0p0" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 0pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;State
minimum and excise taxes&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;span style="-sec-ix-hidden: xdx2ixbrl1098"&gt;&#x2014;&lt;/span&gt;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;358&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;268&lt;/span&gt;&lt;/td&gt;
&lt;td style="text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_40C_eus-gaap--IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_i_pp0p0" style="vertical-align: bottom; background-color: rgb(204,238,255)"&gt;
&lt;td style="padding: 0pt 0pt 1pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Change
in valuation allowances&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;14,098&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;15,603&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 1pt solid; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;13,495&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 1pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr id="xdx_405_eus-gaap--DeferredIncomeTaxExpenseBenefit_i_pp0p0" style="vertical-align: bottom; background-color: White"&gt;
&lt;td style="padding: 0pt 0pt 2.5pt 10pt; text-align: left; text-indent: -10pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;Income
tax expense&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;7&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;358&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;$&lt;/span&gt;&lt;/td&gt;
&lt;td style="border-bottom: Black 2.5pt double; text-align: right"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;268&lt;/span&gt;&lt;/td&gt;
&lt;td style="padding-bottom: 2.5pt; text-align: left"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;


</us-gaap:ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock>
    <us-gaap:IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-9975000</us-gaap:IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate>
    <us-gaap:IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-10000000</us-gaap:IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate>
    <us-gaap:IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-7934000</us-gaap:IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate>
    <us-gaap:IncomeTaxReconciliationForeignIncomeTaxRateDifferential
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-170000</us-gaap:IncomeTaxReconciliationForeignIncomeTaxRateDifferential>
    <us-gaap:IncomeTaxReconciliationForeignIncomeTaxRateDifferential
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-353000</us-gaap:IncomeTaxReconciliationForeignIncomeTaxRateDifferential>
    <avxl:PermanentDifferencesRelatingToStockBasedCompensation
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-601000</avxl:PermanentDifferencesRelatingToStockBasedCompensation>
    <avxl:PermanentDifferencesRelatingToStockBasedCompensation
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-714000</avxl:PermanentDifferencesRelatingToStockBasedCompensation>
    <avxl:PermanentDifferencesRelatingToStockBasedCompensation
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-4379000</avxl:PermanentDifferencesRelatingToStockBasedCompensation>
    <us-gaap:EffectiveIncomeTaxRateReconciliationGiltiAmount
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">165000</us-gaap:EffectiveIncomeTaxRateReconciliationGiltiAmount>
    <avxl:PermanentDifferencesRelatingToSection162m
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">816000</avxl:PermanentDifferencesRelatingToSection162m>
    <us-gaap:IncomeTaxReconciliationOtherAdjustments
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">273000</us-gaap:IncomeTaxReconciliationOtherAdjustments>
    <us-gaap:IncomeTaxReconciliationOtherAdjustments
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">741000</us-gaap:IncomeTaxReconciliationOtherAdjustments>
    <avxl:AdjustmentToTaxAssetsBasedOnSection382
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">3330000</avxl:AdjustmentToTaxAssetsBasedOnSection382>
    <avxl:IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-37000</avxl:IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet>
    <avxl:IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">232000</avxl:IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet>
    <avxl:IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">1042000</avxl:IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet>
    <us-gaap:IncomeTaxReconciliationStateAndLocalIncomeTaxes
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">-4122000</us-gaap:IncomeTaxReconciliationStateAndLocalIncomeTaxes>
    <us-gaap:IncomeTaxReconciliationStateAndLocalIncomeTaxes
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">-4975000</us-gaap:IncomeTaxReconciliationStateAndLocalIncomeTaxes>
    <us-gaap:IncomeTaxReconciliationStateAndLocalIncomeTaxes
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">-7022000</us-gaap:IncomeTaxReconciliationStateAndLocalIncomeTaxes>
    <us-gaap:IncomeTaxReconciliationPriorYearIncomeTaxes
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">206000</us-gaap:IncomeTaxReconciliationPriorYearIncomeTaxes>
    <us-gaap:IncomeTaxReconciliationPriorYearIncomeTaxes
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">24000</us-gaap:IncomeTaxReconciliationPriorYearIncomeTaxes>
    <us-gaap:IncomeTaxReconciliationPriorYearIncomeTaxes
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">48000</us-gaap:IncomeTaxReconciliationPriorYearIncomeTaxes>
    <us-gaap:IncomeTaxReconciliationChangeInEnactedTaxRate
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">216000</us-gaap:IncomeTaxReconciliationChangeInEnactedTaxRate>
    <us-gaap:TaxesExcludingIncomeAndExciseTaxes
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">358000</us-gaap:TaxesExcludingIncomeAndExciseTaxes>
    <us-gaap:TaxesExcludingIncomeAndExciseTaxes
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">268000</us-gaap:TaxesExcludingIncomeAndExciseTaxes>
    <us-gaap:IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">14098000</us-gaap:IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance>
    <us-gaap:IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">15603000</us-gaap:IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance>
    <us-gaap:IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">13495000</us-gaap:IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance>
    <us-gaap:DeferredIncomeTaxExpenseBenefit
      contextRef="From2022-10-01to2023-09-30"
      decimals="-3"
      unitRef="USD">7000</us-gaap:DeferredIncomeTaxExpenseBenefit>
    <us-gaap:DeferredIncomeTaxExpenseBenefit
      contextRef="From2021-10-012022-09-30"
      decimals="-3"
      unitRef="USD">358000</us-gaap:DeferredIncomeTaxExpenseBenefit>
    <us-gaap:DeferredIncomeTaxExpenseBenefit
      contextRef="From2020-10-012021-09-30"
      decimals="-3"
      unitRef="USD">268000</us-gaap:DeferredIncomeTaxExpenseBenefit>
    <us-gaap:OperatingLossCarryforwards
      contextRef="AsOf2023-09-30_custom_FederalMember"
      decimals="-5"
      unitRef="USD">126300000</us-gaap:OperatingLossCarryforwards>
    <us-gaap:OperatingLossCarryforwards
      contextRef="AsOf2022-09-30_custom_FederalMember"
      decimals="-5"
      unitRef="USD">123400000</us-gaap:OperatingLossCarryforwards>
    <avxl:OperatingLossCarryforwardsDescription contextRef="From2022-10-012023-09-30_custom_FederalMember">$37.7 million will begin to expire in 2025 and $88.6 million can be carried forward indefinitely</avxl:OperatingLossCarryforwardsDescription>
    <us-gaap:OperatingLossCarryforwards
      contextRef="AsOf2023-09-30_us-gaap_StateAndLocalJurisdictionMember"
      decimals="-5"
      unitRef="USD">16600000</us-gaap:OperatingLossCarryforwards>
    <us-gaap:OperatingLossCarryforwards
      contextRef="AsOf2022-09-30_us-gaap_StateAndLocalJurisdictionMember"
      decimals="-5"
      unitRef="USD">17200000</us-gaap:OperatingLossCarryforwards>
    <avxl:OperatingLossCarryForwardsExpirationYear contextRef="From2022-10-01to2023-09-30">2036</avxl:OperatingLossCarryForwardsExpirationYear>
    <us-gaap:IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment
      contextRef="From2022-10-01to2023-09-30"
      decimals="-5"
      unitRef="USD">2700000</us-gaap:IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment>
    <us-gaap:IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment
      contextRef="From2021-10-012022-09-30"
      decimals="-5"
      unitRef="USD">2200000</us-gaap:IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment>
    <avxl:ResearchAndDevelopmentTaxCreditsYear contextRef="From2022-10-01to2023-09-30">2029</avxl:ResearchAndDevelopmentTaxCreditsYear>
    <us-gaap:OperatingLossCarryforwards
      contextRef="AsOf2023-09-30_us-gaap_ForeignCountryMember"
      decimals="-5"
      unitRef="USD">12900000</us-gaap:OperatingLossCarryforwards>
    <us-gaap:OperatingLossCarryforwards
      contextRef="AsOf2023-09-30_us-gaap_ForeignCountryMember_currency_AUD"
      decimals="-5"
      unitRef="USD">20100000</us-gaap:OperatingLossCarryforwards>
    <us-gaap:OperatingLossCarryforwards
      contextRef="AsOf2022-09-30_us-gaap_ForeignCountryMember"
      decimals="-5"
      unitRef="USD">10600000</us-gaap:OperatingLossCarryforwards>
    <us-gaap:OperatingLossCarryforwards
      contextRef="AsOf2022-09-30_us-gaap_ForeignCountryMember_currency_AUD"
      decimals="-5"
      unitRef="USD">14900000</us-gaap:OperatingLossCarryforwards>
    <us-gaap:DeferredTaxAssetsGross contextRef="AsOf2023-09-30" decimals="-5" unitRef="USD">7200000</us-gaap:DeferredTaxAssetsGross>
    <us-gaap:OperatingLossCarryforwards
      contextRef="AsOf2015-09-30_custom_FederalMember"
      decimals="-5"
      unitRef="USD">25800000</us-gaap:OperatingLossCarryforwards>
    <us-gaap:OperatingLossCarryforwards
      contextRef="AsOf2021-09-30_custom_FederalMember"
      decimals="-5"
      unitRef="USD">12100000</us-gaap:OperatingLossCarryforwards>
    <us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch contextRef="AsOf2021-09-30" decimals="-5" unitRef="USD">800000</us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch>
    <us-gaap:OperatingLossCarryforwards contextRef="AsOf2021-09-30" decimals="-5" unitRef="USD">2500000</us-gaap:OperatingLossCarryforwards>
    <us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch contextRef="AsOf2021-09-30" decimals="-5" unitRef="USD">800000</us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch>
    <us-gaap:ValuationAllowanceDeferredTaxAssetChangeInAmount
      contextRef="From2020-10-012021-09-30"
      decimals="-5"
      unitRef="USD">3300000</us-gaap:ValuationAllowanceDeferredTaxAssetChangeInAmount>
    <us-gaap:SubsequentEventsTextBlock contextRef="From2022-10-01to2023-09-30">&lt;p id="xdx_803_eus-gaap--SubsequentEventsTextBlock_z3bCaqjnWyw5" style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;Note
8	&lt;span id="xdx_827_z2tGny4WyLe6"&gt;Subsequent Events&lt;/span&gt;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&lt;b&gt;&#160;&lt;/b&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;The
Company evaluates subsequent events occurring between the most recent balance sheet date and the date the financial statements are available
to be issued in order to determine whether the subsequent events are to be recorded and/or disclosed in the Company&#x2019;s financial
statements and footnotes. The financial statements are considered to be available to be issued at the time they are filed with the Securities
and Exchange Commission (SEC).&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;There
were no subsequent events or transactions that required recognition or disclosure in the consolidated financial statements.&lt;/span&gt;&lt;/p&gt;

&lt;p style="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"&gt;&lt;span style="font-family: Times New Roman, Times, Serif; font-size: 10pt"&gt;&#160;&lt;/span&gt;&lt;/p&gt;

</us-gaap:SubsequentEventsTextBlock>
</xbrl>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EXCEL
<SEQUENCE>53
<FILENAME>Financial_Report.xlsx
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
begin 644 Financial_Report.xlsx
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M?!^2!F.,6_0T7X\48JVFL:W&VC$,>8!8\PRA9CC?AT6:&C/5BZPYC0IO0=5
MY3_;U UH]@TT')$%7C&9MC:CY$X*/-S^[PVPPL2.X>V+OP%02P,$%     @
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MUJ31^^U7O:/](:.C4JRO2*Q SMJ3LR#U7I^Z*W&]X6CVNB0R;'"YKC6_ROB
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M9[O,*0'86@"^7W,@@>Y!7SW[GQJ6_P)02P,$%     @ TH-[5\FN5>JX @
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MY7EA_\PQH'POQ"-JSC4-GBYJ?H<&5\<"O5!H92G:"7[(J]82'D^'D2*OYLH
M#VN36S_RXX%$(RYT^V6;">=%H3\F\USMX.ERYZ$5<MJ.-]#C"3%2ON%AF7+;
M+]Y,&*\?W+4)Y88CE2@^%SQXNN)IPZ;/@N2B/QS=6=&@)H88!$[_"#3CXFB@
MS("#\M6)>]KL3HM<4K&M/C5(F/2>J;JI;-^VGS,^54U\[_V]_LQ1M=YGFOH;
MR1<BMCDTRP7= *5S%\&D1/W9H7Y0?%<UXB]<05M?W6:4I%1H /R_X5R='O0
M[<>?Y;]02P,$%     @ TH-[5Z=;QLG_ @  8@D  !@   !X;"]W;W)K<VAE
M971S+W-H965T-2YX;6RM5E%OFS 0_BL6FZ9-:@.!!$*7(#7)IE5:MZK1UH=I
M#PY<@E7 S':2[M_O; A-4A)E4E_ -M]]ON_.W'FXX>)1I@"*/.59(4=6JE1Y
M9=LR3B&GLL-+*/#+@HN<*IR*I2U+ 30Q1GEFNX[CVSEEA14-S=J=B(9\I3)6
MP)T@<I7G5/P=0\8W(ZMK;1?NV3)5>L&.AB5=P@S4C_).X,QN6!*60R$9+XB
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M J$!^'W!N=I.] ;-M2KZ!U!+ P04    " #2@WM7@*RPX28&   S&P  &
M 'AL+W=O<FMS:&5E=',O<VAE970V+GAM;*U947.C-A#^*QKWIM/.7,Y(@($T
M\4QBFFD>KLU<>NVS K*M'B!.DI/<O^\*'+!!*.G5+S;@W47?I]W5)^OB2<@O
M:LN81L]E4:G+V5;K^GP^5]F6E51]$#6KX)>UD"75<"LW<U5+1O/&J2SFQ/,6
M\Y+R:K:\:)[=R>6%V.F"5^Q.(K4K2RJ_7;-"/%W.\.SEP2>^V6KS8+Z\J.F&
MW3/]N;Z3<#?OHN2\9)7BHD*2K2]G5_@\):%Q:"S^XNQ)'5PC ^5!B"_FYC:_
MG'EF1*Q@F38A*'P]LA4K"A,)QO%U'W36O=,X'EZ_1+]IP .8!ZK82A1_\UQO
M+V?Q#.5L37>%_B2>?F-[0,T ,U&HYA,]M;:+Q0QE.Z5%N7>&$92\:K_I\YZ(
M P<\Y4#V#F3H$$PX^'L'_ZT.P=XA:)AIH30\I%33Y8443T@::XAF+AHR&V^
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MT%J4S>66T9Q)8P"_KX70+S?F!=TYV?)?4$L#!!0    ( -*#>U>N(81$,0@
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M-_R:%S@_)N4ZS2LG8P]<WGT3\$XL#^]$'@[J8M>^]'=?U'6Q;3]N6,(YMBG
M?W\HBOKYH'F/\/AFZLW_4$L#!!0    ( -*#>U=B<3I8%P<  %H0   8
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MD+0XT$DHQP76H=P7;'/LB6JP+W%G6,N6L4/R,=:=A1!,E:F/5J8/_IZ-7/S
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M0K?:=CTG*XR8APSZ]C<P3KY=(G7]H67J$)5N6)/4,TK!1'20$U"I[[%;C/U
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M+F:O7TTR4X:'Y%NY/6Y]PEU4?NXQGU'@#7A?>S"C?^ #QO].N/P/4$L#!!0
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M^.L5G98PN,#>X/U[T9V2W)BK>C$I8\/&UNIP53)+7?M9M7F55YT^6PZ\43#
M;<@QGM,Q;X5?ZFUZZ*5QML WWG$<FILLLL'L@$C(3M44=8A-3GE$_"_)X9%E
M*<9[37<X&WTR<;]3_)F990LVM1U9C^W6=FPQ=CD9(B?J0:N1<ZD(JCNR=3"=
M,K5WL04=%'FEW\FT8=.*>2+.@"0SZ7$;RWUD$IL7<I2V&SM5]98U'B7]H?_$
MQ:;SD,#0AD@7NS7))T5(YE-#]BDQ?32JK_H!Q(ZG'T_*)T[,7>;-)\^M:!]9
M?68,KBBN@YB1;[&?"PLK:TE2V;707 -D5O8[]S#3L4RO!P*29 6BGWHE \U+
M7>T-AC.(O%%[ P8_>O7RS<UC,^P@9W\UBV\N9A<7%^:](B0V"R\3A/2S=Z^C
M)XXP%-.DKA@X!7H%?@N@<S:Z:5'([:ZK\*0:/)E#/QSZ3E(5>MKV0-[=*2KL
MBD0;&BL*S8B2L!JA>P9$KJ?O6)+]-SU\+;.^&0"(2'AHC !"8[>[NMV367)D
M23N/09:VL:M*I9 1WCDCO"Q%>'ZG,P9X")\,@HBJL"ZA#=Z_:\1W3T/3!"D+
M)]57D'')F[6J X<'9$6[DC2L@SW(W(#)7%P]K-!VZ[RI_E XX+WHS?NW+GI.
MXH1'7<H*H-T-6?4$<@F,\G#;$SHWOU8$)7I2H&R7[X7 ;4ZV=;E/SU4,7$+R
M6';N-[81 [BS!0P#!?LZ+;DS)]XL+S9 K"1=OQX?WVB^+)'%J=@JB=UN"=R6
M.=%UTY;1(@6T<7OCV62^0^3]/CVY1&5FX+Z8:0_I7,:.N*' I.9SYUA#T=I
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M6:R>9*_2L,"D\N?5J67>VX+14G9=DB6GPTA?UM2U30L4)>;X9T8W:!%Z2]@
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M"6@.6UY+=ZOW'Z'+9^CY,BUMT])]&\NB@&:U=;KLP*B@%*KM^6-W#P> R4L
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MF5&U.X[C9<9VNO@A3<9)VV>(O!+1@  #@)+5K^^Y *DE5MRT#Q)) /?<<U<
M%VOK/ON2*(B'2AM_V2M#J-\,ASXOJ9)^8&LRF%E85\F 3[<<^MJ1+*)0I8>3
MT>C5L)+*]*XNXM@'=W5AFZ"5H0].^*:JI-O<D+;KR]ZXUPW<JV49>&!X=5'+
M)7VD\'O]P>%KN$4I5$7&*VN$H\5E[WK\YF;&Z^."/Q2M_=Z[8$OFUG[FC[OB
MLC=B0J0I#XP@\5C1+6G-0*#QI<7L;56RX/Y[A_YSM!VVS*6G6ZO_5$4H+WNO
M>Z*@A6QTN+?K7ZFUYX3Q<JM]_!?KM'8\[8F\\<%6K3 85,JDIWQH_; G\'KT
M#8%)*S")O).BR/*M#/+JPMFU<+P::/P238W2(*<,!^5C<)A5D M7[T-)3MR9
MW%9T,0Q Y/%AWDK?).G)-Z3'$_'.FE!Z\9,IJ#@$&(+*EL^DXW,S>1+Q(]4#
M,1WUQ60TF3Z!-]W:-XUXT_]I7Y*>'9?FBGCC:YG390\I[\FMJ'?UXMGXU>C\
M"6ZS+;?94^C_RNU)Z>/<?K.!LIG81Q:_.&E"IM+'V\8IL\PP+S8DG2".FX#7
M U5SR'2N[PM><FNK6IH-JB\G%$\AGHO1X$2,XO]8P!.GLW/QJ:1LR4I$JV0M
M/5<&.0>1=4EF!R -?I5U0?V-KV"%C51;0<BQ6D=:!DRS6=+E990J:(464J,A
M!$$/:$J%"@U6".F(Y1O6-LB2@>*_&VB7)G)Z+B8G_=$(-HJ367_,+X,S_&;B
MOJ63?4T'VO& ?9T=W[_240R>"<GR=A3"!E3F&W%MY(H>Q#4Z@9-:26$7<>%N
MX/Z%K.KSMR*'^2H,$ WE12Y]N5.6860;@2.@?='4Z) +I=EUT"!%KJ6J@"!R
M:TS;0=<JE(]D7SQ[/1F?GB,,QC12=Q8$^0"5") 9_/^<LZYX*@L>.1/,$;W!
MJ9@-QF(ZF.)Y$G^O\'T=LF,J[[8@#)]HLZ?D7".W *R; B^,>P+,,SS/(B9G
M_;>B(&IG41%P(/PBL <M?I3>D_?;"52%(X1BW^(*:*)=IY 0I-52S1&4L$%&
MP '1>ZB9@@(Y; 8D?E O,Y4R@JW 0M7):9Y5+T4[[6O*U4+E6Z9Q/U1!M16T
M%6(W0' GJ5!I*U5P<#O9@_HKD1"9H8?&,S??@.AC'9R7.TMI)76#$G]L9X/<
M<%$MAV(7X<YOZ!"(<O3&7&J)>9$.+P7@,MZ?"X%498#*PIVQ+2!7V"JT%2@V
M<:T4<B65YB@/'A<9AXU] 7N0_T&9)KW'HF#LSL!#DC@C@6"F+:I(LFU0R0<C
M?^C=#C+Z*W:NW?QWM3PPUJ&TS;+,]O-G#A1(<">1@;67(('"J#%<I.J56G<=
M-KD"7 "*ZDY^/1J)SO?1/ #4Y)0M?'('%?U(XOK3^Z@OHO-1B(USM.*#V1[)
M;;OX@GQ2BPTWG!;?=T&*O?\@Q:+F5B_S7%CXC*L!KKA;Q)S+9*=MC<J*.TL.
MSZ:>PN0JN8FI*@JUP-:4&@CJ"/TWR*T'<G(!$3OPA*,OC4(DN4M'?1UDH;Q<
M.NJ<B^'L:S-3.4?1M/?%SI9,],W< SJF9UV3U+[/4<MMHXM.J9#%7TC+F *P
M*7FHEILXP'S;_(:#:K;?H@JC8UH&60P2=&L^LN]V<J10D0*/B&[Z7:UWJ<0[
M>&.Z&BBH@GM0&P%\ "&]Y;D-&L>RB8MJZR,8"N(SMGN\Q#Z0E.\2))D&0VW7
MYQ!DJ5,3@FDQ((2R[0!VU@_$;3(5;+-C"758BJW9"V<K-/KQ&9N!AC^)O8ZO
M-#Q0X[2$Y6AL;>JT#1E4O_9/K(,V_U@:&9FU0HJW"1QWE%'PC]JEAV^XZ09F
M(9OBL -RJ1@;-PKT5DJ) 55V'7M:3'B,1"?L:.[<@53Q)7N3?;%)N<[;->M>
M-%PU W'LB#K<NRI4Y);Q0L1=HC$AW1JVH]L[UW6Z:NR6IPO;.T2?>YNF!41'
M@].37JK\[B/8.EX\YC;@&A-?2R0A.5Z ^86%8>T'*]C>1*_^ 5!+ P04
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MAO/IH(E^=^--Q9\-5L9[4_#E5DG02ANPOC9XOVQO2$'_'>GZ/U!+ P04
M" #2@WM7YF9.5L(+  !/'@  &0   'AL+W=O<FMS:&5E=',O<VAE970Q,RYX
M;6RU6=ERVS@6?>=7H-1.5U+%T%RU9'&5G:TSU=U)Q;T\3,T#1$(2QB2A *0<
MS]?/N0!)48ZL\73-/-BB0-S]W 70JUNE;\Q&B(9]J\K:O)YLFF;[XOS<Y!M1
M<1.HK:CQ9J5TQ1M\U>MSL]6"%Y:H*L_C,)R>5US6DXM7=NVSOGBEVJ:4M?BL
MF6FKBNN[*U&JV]>3:-(O?)'K34,+YQ>OMGPMKD7S^_:SQK?S@4LA*U$;J6JF
MQ>KUY#)Z<972?KOA#RENS>B9D25+I6[HR\?B]20DA40I\H8X<'SLQ!M1EL0(
M:GSM>$X&D40X?NZYO[>VPY8E-^*-*O^41;-Y/9E/6"%6O"V;+^KV)]'9DQ&_
M7)7&_F>W;F\63UC>FD95'3$TJ&3M/OFWS@\C@GGX $'<$<16;R?(:OF6-_SB
ME5:W3--N<*,':ZJEAG*RIJ!<-QIO)>B:BS>JJF0#+S>&\;I@;U3=R'HMZEP*
M\^J\@0C:>)YW[*X<N_@!=E',?@&'C6'OZD(4APS.H=N@8-PK>!6?Y'@MM@%+
M0I_%89R<X)<,!B>67_)7#&9OI<E+95HMV-\OEZ;10,T_CKG!"4F/"Z%,>F&V
M/!>O)T@5(_1.3"Y^_"&:AB]/F) .)J2GN/_W,3O)[KBROZI&>%-VVEL_"^0#
M^VTC/.S;\OJ.E;1BF%JM9"Z8Y<I:($&#FJ&2:$[D;AN0WFQH7=:RD;QDC= 5
M2!E 1#SO;\^5@1:W K'AAJU4B8)BV%-9LV:C6@/US+,7WC7*5M&6@A@=Y> !
M48VHED)[@)5'L")LQ?0O\CX=%7K&HFB._[.$'I.(O:NVI;H3PDO#Z.G-,W8E
M:K&2#?M<PIZQ0S90E5.9@-.+YSG<I^6RM07)\!WD&+8E&N>DZZY6=5QA0K,1
M[&,-S]1PT!>Q$W4K$(5"!"3&T>9J)S3$E"7[':X4!;MN>".,1^6J8*+3U02'
MK]F]UTR4<BV7<%VCV);K1N9RBXW,>KB35?$[-EB!V&YI,[W-6ZT!$V; NVV4
M!A8DH&,\9]E1.ZZ!-<*)%NNVY&2Y<69U]EN)" CQL1QZKT)FQ6^ @Z*01 :>
M*-#YAN(V]C&06+.EV/!RY<&9^U?8-W++VU9CQ2,)=X)K)JAVL0$G0_GQ#Y2H
M>"$>$KLW>FS*(V'[$"OB<1J];\:4'KPTEG[&XB0F_&8$Y2A>L)_AO+7U^P%F
MI4&/7OX36"1'YR67E<O^4JSAZ:U6N1"%Q6ZSX0WC6IH!)4KC#=H[K&BUL?8L
M6P/T&SCZNLTWY++&XE43T480;,H[V)D+W6",\#V2U= +EG.*'ZL56[=<<P!(
M.)E65-ODJK(B2&VS9X[2@F0 82%R2;%<\9W2?%G>]7#M;55ZSP_%3Y4N-]7*
M.\JR5@U2>@?DT;+05+9X0>DGF%BMR&7M5M5C$3_^,(^CV4M#805_67!*0=0#
MCB(*<DH882NLPWZO6:&0P21OB;Q$PG2^)IU73C$,9H6%WJD(6;7_@\I0F#+L
M$0I>;Q U[W.K\PU5QS^YIJ 8=MEXWZ>+U8C >9@W&UXP=$(_#$.6!+/X /N&
M!+!M+^"V%X!80P]KK_=K:\6\^R9T3LC[K*F(O/NVE8 =IB#A19EC?P8!T8S]
M@J(UM3JE7M2_B>( GY=;+4L61_;MU.OUNFY4?F,C%[VT9=(F!V91ERVVS,=A
ME'EV(_NTW2]_&N4HB^:^W><?1<12<5V0U874B(.BI-@B>#OXGULZ]JFJD<\&
MM3-'!## .B%/B1WQB<.7=A^MVN_1RV<^N]W(?.,1)X=^Y0K(FGQIO6RU5EM7
M82A,P#XJ1TZ1=R\Y7%\82I=!.;_KZ_2T[QI$3<C!&.PBM1K;:C'M86"555NQ
MVD6.6G.K0555U <IY(9UHX?35AK3BGNE#V P"&.(V&895;UH<=S]?^-U2Q6(
MW$Z[G/.OK+,'_](2O7RDAQ?'/,PZ#YL'/.S]3SSL'[B76"%]I2&T_-]]';IT
M>&2#1**GX=1/,]>3CD?G%X[<9G'FCTK#T=B@J3TJ-M@WCHVKHL.RM63@O+QS
MSM^H$N8:#WI1<8A3IPU-2+T;:!H=/#RP\YDK(-8MY.Z]H $,ME!C&*19:4E#
M"LYMTH"?4V PV&<=:ISYM+T05,$Q6-D"CS"AF1BYE*5L;.OB-I 2#:D; $57
M!)'L5 3W?8_4IYGS0"+K.ETC7=MT< 4H'!7>TM3;,/&UI7G<M<H5EQK*Z1O1
ML!TO@14"$NE'G2)@'U=[Z&,BEC3P1N&3L:-9UQ*=/"*S<7>+O0G,F>"T<8T/
MZACKSQH#.%A"Y2/:K(X55Z^#NIVG'/9=T;NO2>"*_5 -NZ@Y<XI17NPC35F#
MC[WBZ*K*%O)N'H9EE"?&6VE566*2M/=XI[(322BP[B1C(<MQ,S0M=KH\$$U_
M/*9!',8$S=Q.UZ8DW7KDF,C0R85GCUL/(SM $S\Z\R;^/%WX"_31J3^=1GZ6
M9!;Y;I2E <3=Z,A_P=VR=A=%]L9EB:Y]T&O<)0QAN; 5A?45Q3PX<P]#Q.&,
M?)2K]Z>]A$&W[A_8)08=OA;#YP?K_\OU6KL\DS0P(\7R?JH [WN#!4T4[#W!
M[@^+-XLZ[U,'EZ=GS_H_[]-^2/&_GX<B8-A/\&41)BP+9JDM85'\DD5IZ$=)
MC,(9>1\ZW,5^DLUME8G"($K8+ AG/8'W7NF5L$>YISB8^K,L9,_8-)A/P1<N
MZ[?UAF!;BI*5)3-LBX,L9E$PG[/41V/S:8HYK3BV)WXT7?C3: HITXBEP0)/
ML1]/9WX2+@:E(W^1+:S2BR ):6\X4@;S&?;T1C_P.59Z!F8S-!-2.DE9&"PR
M*#V-(0*SVL@)<3;SPSEM=%/==.1=[PVAORP?(?JT&Q+$R8\0P]D\1#BBF)P]
M8^AA\0+]8+KH5<<Y0QREAP=#Z!^EH,1$D02+=$3^5Y/*4-T^(@VE@C,$9FT3
MYK#*FGO9]&A9^Q3C748-"_L$TH*N@\F([S9]N:^/<9WK8,)W)V!D-76A0?$]
M_XZK]YZJZV]J\$,I5WT7V6':0L3[-X?6>V>$I1@!H".('\]#0C%0#=0 :8O1
MVIE=\.@@$48(&PABI,S,S_"4!@DQB>>CM3.[ (*,"!9$D"%/$.$L!2Y1!:;!
M@J0F@$*$C#S#0A2"8$$$D=4)>32/;,F=!]B""I !^5 IFZ?V,BI(,^_,;HXP
M2CF2;!;;U)L%Z0('CP '_ SH"AW)/,AFW@C TR!,'8KWJ#QSN"0<WO8%M(\@
MNE)W.+,=>&B]O8<[A]^KZP^7=1K+SEP*I ' C[)$_B'%:&66D2Y6%?Y]L>[$
M8]3(>9G3W1%IZNZ("HE#K1;(>;3.YE8<GS*Z[F>[>WEGH>K&\>[N@7UM%3'M
M)@T'F^.31I<@_1&@=XB= NUMI:R?X\5SS"#B[GBN!@?W+S@,J'6-;.Q."L_=
M15T^/H&*;_1L[4!PR6>(< JX'!ZGUZ)&^,KNU.#F4+K?W(F>PW X$78NIR^%
MV(E2;>G(/^PZ?>_TP8GQCH@!IG!<LY>G/MTY)<!IY'WIY'GWY6&ZG@.3 &F,
MI@983D/O-]6 ]X.N(/O]9&;/]',\+-C<CY.(7=8>KU3KQBU[ L#!"$@I[VAG
MVJ'K$,V"PP?]5 '5NOL'!P["&U!NF13]('DXV-%-ET/_5<D!"L1"E53<'$N"
M$6VH% ;][O[5\1D5_N]2C^. 5CE4'9;M4SLM'D\81P;=#^,7:6Z>KS0-\715
M"UO1/V!>$L"[3^@N)<)'&,P2]H3ZN:#3K&>K[J@2/+4#W3/D[Y0:73:SPXYW
M6>-47A*JO9VBVUY[IIEG--P\8?.4+FJ>L$42I,3]K:2S5%UX5H&0*MR3>Q_?
M1\\EX@$X<I2LM3WQ#CGUZ-&S&WZZ 32R)6LTBMMY6HNNV'C=:>E(W7C@A-(?
MQH^<2([]2'0^^I&O$C"*?LJD2SL@W/W>-ZP.OY9>NA\)]]O=3ZTX@J\E]4NQ
M BGBF4V8=C]?NB^-VMJ?#)>J:51E'S>"HU32!KQ?*1C9?2$!PV_(%_\&4$L#
M!!0    ( -*#>U<@<4"^20H   L9   9    >&PO=V]R:W-H965T<R]S:&5E
M=#$T+GAM;(U9VW+;1A)]QU=,,=ZL5(50N/%F2ZJ2Y617J<1Q67;RL+4/0V H
MC@U@&,Q E/;K]W0/0(&T).O!(B[3/7TY?;H'/MV:YJM=*^7$7576]FRT=F[S
M^N3$YFM523LV&U7CS<HTE72X;6Y.[*91LF"AJCQ)HFAZ4DE=C\Y/^=F'YOS4
MM*[4M?K0"-M6E6SNWZK2;,]&\:A_\%'?K!T].#D_W<@;=:W<Y\V'!G<G.RV%
MKE1MM:E%HU9GHXOX]=N,UO."/[7:VL&U($^6QGREFZOB;!210:I4N2,-$C^W
MZE*5)2F"&7]W.D>[+4EP>-UK_X5]AR]+:=6E*?_2A5N?C>8C4:B5;$OWT6S_
MK3I_)J0O-Z7EOV+KUZ;I2.2M=:;JA&%!I6O_*^^Z. P$YM$3 DDGD+#=?B.V
M\IUT\ORT,5O1T&IHHPMVE:5AG*XI*=>NP5L-.7=^5>>F4N*3O%/V],1!(ST_
MR3OIMUXZ>4(Z3L3OIG9K*WZN"U7L*SB!*3M[DMZ>M\FS&J_59BS2*!1)E*3/
MZ$MW_J6L+_VN?^*=MGEI;-LH\9^+I74-$/'?QWSV&K/'-5*5O+8;F:NS$<K
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MC4;*]/^\\"Q,XH5@E"9O^E] 92,UMEG+Y@98@0&3A9@O,OP+KFHGZQN]+%7
M@4)0+>)))J3SN4B3M,=-H.Z@H;Y1G"OCUDABMA!9)J9)\*<L6S8AD)0W6>><
MH5T^!D XFLT0!X;=- VC^8*N"&_S*1!(>7E,ZM7.J\>N+H)&Y:;.=:E](+#W
M  +JCN(+PY&B-<H1-=,ZT]R+E2H @7*X%HCP'NY7L:6N2NV1P<5JL*$UI2XD
M/5OI&DYK60:D756,2N2?5]XC>58HHOT75("V+RF  "Z^Q.E#X'MJ"VC%4M5J
M!:PB+-^&A.. BE^$B]G$%W],K-(1P2Q<I-D#J0RIJB"%'A\-DU.?I:-XQK23
M3E)(?E 8%*AZ@T*OD' %S%"42U^2SL HU C/$878JY&C:10S?\49@P>ELGB1
MQG]=_?;IBH)4MCPIQ=/)-]7R?2W7W9043Y.CZOA0@9C'T^ /<C_8]*K$4%6"
MNN[7SK(XN"B^8'8AQ 10/L"\]QP;]1NFH(_#W< 3:?0,03 =V9#I&?2->"4I
MD5"4);YYL$AI<N3<8QWQC)/$!];G'MDF_!P?FMJT2K0;"LFFT< ZX_R?[,*F
M,;>:8YQ$4Y%D(IL'/R,&N2/@=D0":#\ KR\^^XV+"0+J3<50IZNVXEH!'6G;
MU^<N&I.Y2*;SX)(W "K%;<],8L=,H, LC-#>XDDXC9AKL\5D6!D]8;P2,Z+]
M"9$_U(H+&SS1Q*C,NR%!K&7A!X2^EBCVSS8;*)4;A.Q.8W96Y3VVBY/I&*8E
MZ3@3K]+9>(:)MBS)CRU^4;LW1 R&3-4\<Y A$X[,J_E\/-TMSV6-U;RA5CRP
MT)X0 ,UJ&B*P73R%0#P;$T>D2!=V2_@F6<"$\0)7XQC-B%9EN!V,1$+Y"".J
MP-ECX4;M_-W"1L^).U#+6ZE+B<8##;J@TAB+O]8*!NLF;RL @U/EH1*R8VZM
M*7*M)4;NWE".460X%)'^W8#VI2UNN #D$L<K3@^QY2V2L 1ANOLGVI//I(9K
MN:,E3/0>K<;3_F,>:AOLM8>\A5IL[EEQ+-XJMGI@:*^[CV)AX%-M7"^*I&!6
MU*AD+ .?@J;A>T7C9:F_4L[PN&8)?C_0%3! X*W2+*UV1._WI$;8^2H?]68M
M:0)%)A22L"PU3DS,Z=_BOF]:R9@A02>'RY:&/3S^U2RMN/!13*)X)HX^7?YZ
M<<S:*P-")#22=5<?+X&]K"^ZCFOII1%-QVOBD->XM6([WUJY&FHJ+KER(-YW
M<-X;&K.A\5A\!MY]-R8S]@NV JDAE-N'<<K'C2T"?>(8]#*K^-RLG58<@D B
M7XZ4$>XP(MSVHP!9[X\0>P(@I,&"VM0_'2Y"VR(G4=S%3[22AI!;[(P$<@H:
M/CAX[_9G0S\O/&&W'_HT'?QSTQ2,@JW&>:7/#21Q=/?@EN*F(0K[MGHHU:!,
M,,=G:&B<U#5CXH.QFFS8.TLA'B61QF#T4HAT;?OY:H]"O[2-MH7N/D_ _%N)
MEM-:;B!^8/,];'@H&PI9CH\X.,@%PWWYJ-8NOZ",1=>)U9U$SY'>^.7]ODVT
ME=^>(]!B3&LX3:% ^@Y%>Z,.UHH6V2L#3U!VH_C+2]<6%7>&4E?((SONR7[/
M$Z*%[QA]N".!"]5.S[U:CSGD 6#( ;" ALG&UQ+*)YITY<-6[CJ[[3D,9PC5
MU C(1T"J;LFTHL/@(YWOB&*?1&_>__$;7\5OC@^ZX4$>&O0'M>5H;Z# GU5V
M@P@[^)@1USC1ZUP]G:6>$X;3U?,>P63?AW;GO&#?\DH2;3.@!PY(0FS=0MT@
ME1W(23_7#18Q2TRB?Z '5"V-F[=J,"G1:K.M56/7>H,'L!#\3*(6L *=HM&[
M@&?FM2GAF/4*)20;I3Q=(!7:%"$=,+8*$,"OA4TE7CW$Z"'#X[V"!=<4+;<X
MN1<TZ]H"'0S%1O-Q=]YYZK@3=^0#\P%2;@'2A2^1QDD& QLM 3ZV\F$$H.@\
M1&:[UF"X(6%A=IN,YS3(Q"+"13*>\&^* 6LLWKW,[H=>1TMW,3EPI+>._M2F
ML\_N&[AI&]O*V@V/$@CC^(739:$+;ON<I8+P_< MQ-F4?':(!^-!U]+^1,H+
M@4ZK"PT.5;;C0A!1H:UK]+*E#TL(!354RUBQ+4+:/T$'OU5^0 !S2O:=8B-Y
M#'4^?MAOJ?:'3.R,7F4[:U8M?46H;PS9VE'$@%,Z0X.AH6-QQ5.0]YZZ8L[S
M(TW!UO'HS+)HNVTW87$,.#%;TY8%V;21]RS5;OA3.0K2]9\K_'#TX/G2CVT!
MNP]=H=!4J/<A65$H&@ZH>EG3_M2J[A!*\HP%"H!2[6^68\X;B\<^@IX,/E!7
MJKGAS_#$SO#)?ZO>/=U]Z;_P'[@?EOO_)OA=-IB+K"C5"J+1>#89B<9_>O<W
MSFSX<_?2.&<JOEPK">Z@!7B_,L;U-[3![O\_SO\/4$L#!!0    ( -*#>U<=
M=\6R"P,   $'   9    >&PO=V]R:W-H965T<R]S:&5E=#$U+GAM;(V5WT_;
M,!#'W_M76$%"FS0U:5J@@[82[3IM#TR([L?#M <GN386CAWL2P/__<Y.&HHH
M%2^.?]Q]_+US?)[4VMS;' #98R&5G08Y8GD9AC;-H>"VKTM0M++6IN!(0[,)
M;6F 9]ZID&$<1>=AP84*9A,_=VMF$UVA% IN#;-547#S- >IZVDP"'83=V*3
MHYL(9Y.2;V %^*N\-30*.THF"E!6:,4,K*?!]>!R/G+VWN"W@-KN]9F+)-'Z
MW@V^9],@<H) 0HJ.P.FSA05(Z4 DXZ%E!MV6SG&_OZ-_];%3+ FWL-#RC\@P
MGP;C@&6PYI7$.UU_@S:>,\=+M;2^975C&W\.6%I9U$7K3 H*H9HO?VSSL.<P
MCMYPB%N'V.MN-O(JOW#DLXG1-3/.FFBNXT/UWB1.*'<H*S2T*L@/9ZLJL?!0
M@4*VW%)K)R$2UBV&:8N8-XCX#<0@9C=:86[94F60O02$I*<3%>]$S>.CQ!64
M?3:,/K$XBH='>,,NR*'G#=\;)/M[G5@T]$O\.Q1O0QL=IKEK<FE+GL(TH'M@
MP6PAF)V>#,ZCJR-:1YW6T3'Z^P[D*.*PP!\:H3=FKU/Q,X?>0A<E5T\,MEQ6
M','2)>WLH+'3:5H9(]2&)8 U@&*8 RNT1;J<J3-,N.0J!=94DXPXC*O,F_F!
MZZR%(AO!);-(<X5'<T.66RXD3R3T4-,.3%A;0<:$8MID8!C-9H!@Z X JW,@
MF/'$UTH=KH&0,.>=.1VA-BP3-I7:-ESGW 9^>C*.!Q=7]EE>;U\>!;'6&A6E
MT/9=PMX.(]54KT@O;=%(Z.)B+^+BZ/='*G"N\^2=UT+24BTP]XLKH(P+%&![
M3L+R,<VYVGC1!6%<4?NP6BX^>DD&>C4U3.E#9T>I,EQ9[DNA)3IWI_90"2?4
M96FCA*^2STFJ"-9FR06EI7"'F!T,O<\._?GA7EDJP&Q\\;5$JQ0V%:J;[>K[
M=5/6GLV;Q^&&FXT@X1+6Y!KU+\X"9IJ"VPQ0E[[()1JI9/IN3F\4&&= Z^[\
M=@.W0??JS?X#4$L#!!0    ( -*#>U<V)9\LS1T  (]<   9    >&PO=V]R
M:W-H965T<R]S:&5E=#$V+GAM;*U<ZY,3M[+_KK]"M>=14.4U:P.!A(2J90F$
M4\F!PG#.AUOWPWA&MA7&(V<TLXOSU]]^Z3'VV$#J?DA8VS.M5JO5_>N']..=
M:S_YC3&=_KRM&__3Q:;K=C\\>.#+C=D6?NIVIH%?5J[=%AU\;-</_*XU144O
M;>L'\ZNK[QYL"]M<//^1OGO7/O_1]5UM&_.NU;[?;HMV_\+4[NZGB]E%^.*]
M76\Z_.+!\Q]WQ=HL3/=Q]ZZ%3P\BE<IN3>.M:W1K5C]=7,]^>#%[BB_0$_^Q
MYLYG?VN<RM*Y3_CA3?73Q15R9&I3=DBB@']NS8VI:Z0$?/PA1"_BF/AB_G>@
M_HHF#Y-9%M[<N/J_MNHV/UT\O="5615]W;UW=[\8F=!CI%>ZVM/_]1T_^_C1
MA2Y[W[FMO P<;&W#_Q:?11#9"T^O3KPPEQ?FQ#</1%R^++KB^8^MN],M/@W4
M\ ^:*KT-S-D&5V71M?"KA?>ZYPM>#>U6>F'7C5W9LF@Z?5V6KF\ZVZSU.U?;
MTAJO[X6_[O_XH(.AD<"#4H9YP</,3PPSF^O?7--MO/ZYJ4PU)/  >(Z,SP/C
M+^9G*2[,;JH?7DWT_&K^\ R]AU$0#XG>PQ/TQF;\/]=+W[6@./\[-F.F]VB<
M'NZF'_RN*,U/%[!=O&EOS<7S?_YM]MW5LS/</HK</CI'_?E';W#)?O:=!<TT
M?HR_LQ3&^0.R*B>K/VR,@I]W15O0)H(?5[8IFM(6M?8=/ ,[M//:XOXJ75O!
M3P94N-OHC]/%5+^^OGX'F_>/WL(8H+<-['1\0W<./GTRVL2ABJ;2A0?KL,.1
MO.XV1:>+U0JV+_QM%'#AVL[ 0UM<*(^\P/.FXU=K6RQM;3M<MX+>T!70Q:?P
M[U&N\3W\<8QT:VY-TQMZQGP&(^@-3E.EYU%5=J:UKIJBG/2-V^Z*9@^_KONZ
M:.N]-K=%W=/D3D^S-76!0X- BJ2"8&XUKDK1EAMZI0)V:K<CV97.=WZB+(BZ
M09L&;)5NBVR5QMX6R]I,-(],=@_>AE_<K6E90K39P7"9ML5QB\\BQ@F(QI6?
MR,A5,,@6)TTT)BQAYSU\30R:!C<(S5N%>>-[(*+NW&R!G[*'<6$6*]A7,.;&
MPJ@M6)V:Q-Q:(&UXP-L"A-O#2R#SEIYWK>B%[?32U!:$XE%R2U2/PKL&)Z][
M,#$M+6QIV[+?PHH#31B+U\Z#P:8EOMM8D"YZ-OH%^+>>) ^:B8OP>U^M15&6
MX-"88M&V>_P1!6P.E% -E%"4"U:U[6%V\"0MW%"C6,M;HQO7:72K%O2FV,&&
M(QFU;BO3]ZYO2Q$Y^C(D&>:2!%?IY9Y4-"S*MMCKRL(NPEEU\%11XP"X+!5H
M!+C'/8^2O?3/OSV=SYX\R]811G7TA/G<T>X%C@RQ'8C*(,B#A^7H[HSAO3+4
MA>Z(^8E>]5W?#A8&, ?;&P^FI*Z!GA@" UOMC/5\'*WGX[/6\UT+.\;N:EZ_
M&Q@'+'Y%(XX9TK/$Q@UI&D$=CH +"&:VC-_!HIVPJ67=5R8H4;1,UTUQ:S[K
M7^W*Z$5I6>0WK@5_B"+&#7BW<;#,E^ZN >*^7WI;6=A,N ?D[>L>/1OHJWH'
M!N%7N[7(QSU<^OG5L\.'Z.O9L_NP+\DPH&:AT6G!#M($TI:KBSOF,KP;AWQM
M $7!BZ^WRU].$5+'A.0U-@E"Z@8<257H7[MJ^@TLX=_O6G>+AA,_OVTZM# 3
M(3?5UZ!KM@&%OA2*"J8 -K!D740&ED5-QD1O@!%03--HL$, S(HO*>=W43F_
M.ZN<-X5GDX]>$ZP,ZL*85IZE,JZ52%H=D!Z8<%1*"V)#0PV&H=LXC]X%K&S'
M.LDF$S?^!N N/%);(%5-HND""F!6.HMV& QS&29#=@[L .YTA < &+I-:\"
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M ^[" ""P1<31.&G.H\HZ^G::6:2(F[B3D>DA6)Q(#RP0KAH KP;L?$O8 V:
M?H-BM4YR81F>Y@8V*DBYYG([9.=@L+/$4SQ-_<7JCEIN!312D=HM:[N6ZEKJ
M97EU.,-<!@$W?CL[G/?+&R)IIKA+8K9J36U0P!D:27.LM7$P]@9MJ#APW3_!
MVX/TE>0YX5/,*NZ5*V&"PTZL4Q#SA"(=1:M9)^RIIM71%M2863_0Q7-;,1U+
MF9T]1_)\8=;;4,A[;3!SL@,AZ/>AG#VZ'?_"T1091YT:1[_EINQFK;P)!?I6
MBH=<%T38!?H>SF8T&$V;EKJH"%/SZGD^38+HP</R4P::3Y>A3@VRZOB222<9
M!(YA7\U*N< .<%!R50@A?8N:%+ZYE$;^=>OZW80;!TI&@QM8!PP9:\P'4,P@
M#?;<1ACZ.:1?@/B#+3X,:6[QB)C"$"5K6,?7V35P0V!(;:* L#\H\2UBG(0$
M!-NR^#QU6U* 2N@5(K.:LJ\0[F69L>2%J-'\WPL4JRF^5'*=I8-&L_,GC2AM
M>J:N>O[U<5TCFDIJI_PA['B?DJI5L*^9&Q?[S_G?0;(S9BX1'=0UE4>[0NJ:
M*0V9DH[8"N=7%DVFI(9C9H_LU3JEA5-#62$G7TA#I,<IE!%"(>3\N9V4<4(S
M)IF?H]ZE3 I*K. @A9,=$QB>EQB:3!J"8&K1-BB=;K_#.!O@=G0O(?=TGFU%
MH55T,N=4*YW"F)T_AA&*YUA@&56MOW#P8E"TR9W#RG$CM(3\7$CVH>Q#!1]>
MEGA:+?K>P?FR?0BKT,0-BPVBPQV.C7XQ)+R)B!HC,AD[AW5\G*TU^:X(6U\R
M+=0X %,!MHWT/G6M7?9=",U!4; +N-WG9W24G-%A2F/'3V(W>W8HCEIHZ+L3
MG')ZR+9YR0D97+)%>GD\6S4VVRW%L=1:2)VH#7>(A9JEEQRJY&EW.\G5CQ:_
M]J#5/@</F+@>ETEH= F4ES$GQ@@%^,7D\/3;%"M+MQTH3&K;H9SZ4']R3T/M
M.;1M\Y)3\5E1QW>^\4>7,C.46T<)TD^&CG> C\:XA#-Z3"D6@SS@(LZ6]3MJ
M&2X(1&:..*_!8HY +3"$PF\36VPV O?4/ B&F725.O+#0G-ID1OP?9<ESTE[
MN*F9$1U,8@V(LZ/-!1-X?/6/,"%X?&D0H41$2JS'!">O'^=[N2MY. FNE&UI
M>7HY P#KO8XV/@HI>!DPG@!0PFG&J;Y.U1L5#4GL3$NM@#%1F\!.AH*&BY\.
MY1 2#><@[PZZ/;-N2?R(V&.H(2&Z#BWBDWA<+#,N!ZMW\ H5YU%C"D3?,!-:
MT\Z6=D=>C+L-7=^A(DOU2.I71:T.<%[(QDZDJ,R%?XC1&L/;CYV8^*NB^AT;
M"-AC?26[H;$_$!(BM"D4#D=HH$B'&"U('+-BW^!QA\8@VYXAJB>N(.HJ:C)O
M6:DGG(1-^S[&9\)!I,&/3#B_!4*;C%5YU%<R?"W)DW$.@31US$YD[Z:RTUC2
M9414ZAOJ2[-T*FYV_EC<(IUEH)T1SC*, H>_<#8NHZ]R^H/E'30B$,K,N(J]
M[F0<[L#DYU7O#,2R[V?%&6);(DEYQ7C\[63N-'9DAN9VV\9NZIY*G#YK=^:$
M06B#CTXNBVV48$:<FIS^0X/7QKY0GE'N'V\I:17P:<$YZG@40L0B?$RD&PIX
M;!$<.,Z+@WYATIJ 2F8JL-ATB6V37-R:#I9<,9"F,LV8_&F@-3:]QM$/,11U
MXF'<CZG\2U00[FB:ZL6),_ I=>+%C&"@0/TM)&[X<V4L(C+:;ST=+C-1$=B_
M@8L:3UM00(.;=FSQ PUR?TB6W9H<, E'#D(U,EO2V)-%JW^X,$QU>#8A/ZV-
MUA OPHB'@W2F(3SX07B<>L H<B\PF,!!AA&-#SU)Z)?1U<(64+P%"I\L8-#5
M4UP$4 ,Z+REX/O<9&9,XZ)@YZZ6SO1X&]&K@<%I#\3WW5^^X[EA(EGG76FJ=
MZP[.<9S@U8>C#L"H#_<@G&14!4:G^EW&OBC!R?4_-=VALO5>Y/^B+F#G+,J-
MHV/PK&@IU[)U%>8;7"RTF)%0_*M,5;J+0^71.[)%>!3'&<1<MMGU'6?DJ8^>
M*@/I#HG\^-S0EK4H\5N'^<4Z' B-O]9X7!Y#F*B50\V/@J%[2SZ$2EI5X*GF
M6%C;6U-7Z+AO0XHT1&/)+F)A068:]J^HO/6?+E=XZ+FES.F'[#5%K[6&'!(?
M8AZ>5@K"#99B)%;)ZXVI*.A)*3'1D3N>,R=7%"^K\![+C^F2"5TYPP4-::R!
ME<)>;HN:F&[1R,#HD8"F=&B3/F8+9A,PYL-*4F -Y49:"U$Z6FQ.5OL1Q\:#
MY L<F8Z-.KG))EVIL[X<AV:+3+L:/'=DQP<=#B04;I20TK.A,]$-'P[.:LR9
MP.N]0& L3E#;2-1VKFTRF71BT?IX$HIR@+B' M;-;UN1ZANI?6ZF)',03GS'
M[-@D.]]OFXV18],Q3*6(0456&2%FIUU&2F+A#A7PX+)6S/0AIT5^("J[]B>W
M.,.S5RK:'=:%K#R.N>9@?R2JX*Z=ADN0KF60FS6-C]4T!^X?U\YV'6S>>Y3J
MB9B'&G/#:$+IA4.O!S^\!*M&X=K]+&,X"<<=$,U+3D$:3/&IT#TP7FC-=0@;
M!"E>ZE06VG+N7;9O$L6PI3;NAM"")LH5AHW;GH4;*SC<&J&7/;Y9]:48S=32
MD;@?:#L=S)=X?$ _9$_IJ2.F8PO&%O0"/5_JM<##,"8,1R:2H[E&I3Y[4AY1
M<]$AO%V SN5D<#B]<#AM,>["EPP6,D+"VS'3@0JXF 6_(M//VT$/I7 2Z,N[
M)X\D!N=T/M!*I_EGYX_SOT*9<6_E;YR=.=UD\!=.\2-Y=4Q>OTHH$,_YI:H2
MRTG*DKPL?&PXM'#$\Z2$2\/I-6Q7D;Y JCKBJ<XB2\#>P_K49VJ=!I+W4T<S
M7=P#5A\1L\/@&#<M'M?!#$ZX\,)EF5TJ>$:ZU \(7]&9/YV72T/&56C0R7(<
M*D-)VR01KJZJZ_%$:[SB)"70NMQ4<K@CMYHQ%B@T7;AR66-J/W\64&2+B?\]
M4P4)4$+OSQR.>=5+XX(,F!$0))?(;(O/=AO?[T6]EZ@ DNE"BEPIL\WQHWUS
M]#![6IJ H@DPW&9"IUGCLRL^Y&A_T+_BNVJF+_4?O8N@T>M[?1.".K;4I9Q%
MP:62VU,J[%*AD[V\)MFRQR7I#O  *8EH!M_P1J7 3HVM]C-A;P[L'8N+"U"4
M\J3']&QR, D*B+EK^@2/1S,;(:'21(_I'>JA;:*,!C>9\2B<821X<@G[@3:I
M#'0G5PNQ)E!O9IPPE8KA9Y4WR4@;3TOWQAR\\8S&8>$]!.&=8);'/$]TH'O8
M+F[1KR)+C4NW!-&)O'VZV(AP4*(K1W1'"I>CRS+5UYTZ[CDC\O#'_,!SVXI$
M+-YN+]HP1Z+\Y\-3PYSS#^D0[NQ+IW!+AH77%;@L6-'\YLS6-0[AXFF7\9?.
MX?*(ZHLCZI\).&(SY5N 72C-&0ES=G"@Z)A0N%G#ZX\4[&<GOC[&,ZGSJ]GW
ME[-Y!' +CJWV(<8Y.'TT/$$FY:#[0BVK^\>;-*@QC$G&VP\+S\<%3E\4F=>-
M4&?!I#A*+(24$-XPQ.@B:&8XLKU+-^'!<_'PF]PQ 1SPW"BC"1*6>V&D"!A/
M?&''SI:P= @YJ&I^<*02;_ZB$$F=R+<? IN4LYYD=:T8KDRX^QWP_ J-^U2_
M;0Y6?7YBU1<?22<N9U?8YT-G,[,C8>_S>Z=0OB]"2\;/<CI-OR?(@3(X<7B,
M)?GTX?P^J<H,D'T:@1;IF"A?,CE*\*@V';M$PH$YNH&!1QB4DI1<79G?8R>)
MV*S!(1JQX;G)Y9Z+JPP?N.G"2989*\PI492.XG&G\-%XME%TSI)7I#%WVH>K
M; ;)GVIP-"^O&*4[.!N^1B[>2Q*'RE-#N9G'9$#,P858%V_=H9N^@IN6,C?5
M*$,OQT@YE>HOH8%.;J6,%='$"R.6X71&E%Q]Y='\[(QHZHYEI Q;O.8"S;_!
ME>M'XW;^079']-:T:[H)FVX]:3J^+CI^&V_;ON8[IM/C?%7W;T6[QD:_VJS@
MU:OID\<7NN7;K_E#YW9TX_32=9W;TI]X/9-I\0'X?>6 4?F  \0[R)__'U!+
M P04    " #2@WM7Z'EO]ZL"   F!@  &0   'AL+W=O<FMS:&5E=',O<VAE
M970Q-RYX;6R=5=MNTT 0??=7K$R%0(KJ:RXMB:6D4(%$I:HI\+RQ)_&JZUVS
M.TG*WS-K.VX0:81XV9OGG#G'ZQE/]]H\V1( V7,EE9WY)6)]'00V+Z'B]E+7
MH.C)6IN*(VW-)K"U 5XTH$H&<1B.@HH+Y6?3YNS>9%.]12D4W!MFMU7%S:\%
M2+V?^9%_.'@0FQ+=09!-:[Z!)>"W^M[0+NA9"E&!LD(K9F ]\^?1]2)U\4W
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M!^,"Z/E::SQL7(+^UY#]!E!+ P04    " #2@WM7%N;E26H&  #1$0  &0
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M+7F,_?!9FT4)H@^F7&B\;DKSS%#LM"=B[G/.X9@P$"E[KYY9XNI#Y(EA1<@
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M0@WV40-;<5MV:O_%P2?!#33!M6$&.?*23-,XC*N2G+AU%$81]6M:AF46DY,
MYP6G09!I'B91A"^G19C'UF):AD6%3X(;:5CK (HP'<%P&XW\.L%UBF!'2IF-
MI<R>G32FV4L!PFA[)U#U<(1!*6CV*DN8UF .EO>HI\.4>-)]<-S]XS[\"B9
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M!"R1>LP0C?(R&*GNR1(:)'E+D.A@E: *JR+SHA!;M=D*1!%62?H@-OL2UEA
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M?>Z/CP_;_2'\ ^HM%YJTL$33Z'6!WSOE#[;^QLC>'287TN#1U"W7^%L E-V
M[Y=2FMV-=3#^NIC_"U!+ P04    " #2@WM7^!^]U\L"  #N!P  &0   'AL
M+W=O<FMS:&5E=',O<VAE970R,"YX;6RM56UOVC 0_BM6-DVMM#6O0-M!)"BK
M.FF=4%&W#],^F.0@5AT[LPVT_WYG)\V@"JB3R@?BEWN>NWMLWPVW4CWH L"0
MQY(+/?(*8ZI+W]=9 2759[("@3M+J4IJ<*I6OJX4T-R!2NY'0=#W2\J$EP[=
MVDRE0[DVG F8*:+794G5TP2XW(Z\T'M>N&.KPM@%/QU6= 5S,/?53.',;UER
M5H+03 JB8#GRQN'EM&?MG<$/!EN],R8VDX64#W;R-1]Y@0T(.&3&,E#\;. *
M.+=$&,:?AM-K75K@[OB9_=KECKDLJ(8KR7^RW!0C[]PC.2SIFIL[N;V!)A\7
M8":Y=O]D6]L.8H]D:VUDV8 Q@I*)^DL?&QUV &'_ "!J -%+0'( $#> ^+6
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M; #.SZ4T;QW[OG1_)XI_4$L#!!0    ( -*#>U=0?)[+W0,  (82   9
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M;4:;PY0K<X1P-#[7ARSFPW]/4YW0W&*^*JA !):*TCN;**]X=>A1=21;FV.
M!9.2E::9 \Z :P-U?\F8?.KH!S1'3_'_4$L#!!0    ( -*#>U<7BMR6#@@
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MY]7_Y+$NZ_1(N,Z++*F#50N2*-W\YM_J$[$5X X.!- Z@)X:X-4!WF[ Z$#
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M6)0:TW'Q[)Y/Q]E6QE$*]QR);9(P_O,:XFP_,8CQ].!3M%K+_,%H.MZP%3R
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M;#%-JF"@T;[5"%=TRPCSJ4?;IS=J=L"BV9*9[,!>FQT&&>&*WC3"LBT7:F[
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M]';,Z7KH6DV3"71!4TC;!+82T*CPUBK.O;V,=U >(]_Y@CS'\SL6-'T_W.N
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MAVI)O*KWJXYDI:F GYA4];1I9NJ.!%P'J.<SQN2ZHR=H;EW1?U!+ P04
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MIIDI%5:4KJFPAR1>VTR]MB;B7<81.P+3B(]JXB-K+W_(*B@KI9AQ&1?E4N3
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M9 A@*,;(LPDI=M0?+2^!WZSZ_3/J!7LIMN@A-59:.TI7UM^)*:S8FUB6$N]
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MQ2C!5#80WZ^+@K_<2 ?U::?9_U!+ P04    " #2@WM7UG>OQ[0"  #Y!P
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M1:74(2""S*>,;A%3UA)-791BEMZ2?IRI>5\()M_&TD_,;[.0IH >R#-P=!:
M(''"D7V./J'OBP"=?3A''U"<H8<U+3C)(CXUA1Q6.9MA/<1U-83=,P2VT5>:
MB35'G[,(HF, 4\;;!&WO@KZV!Q$7D%\@Q_J(;,MV- '=O-[=UK@'KW?' VR<
M9@J<$L_YWRE 0<S#A/*" ?K[ZI$+)C^+?W2*5XBN'E'5BDN>DQ!FABP&'-@&
MC/G//V'/^E6GUBG!@A.!'2GI-DJZ0^@[)854\A$R6,8"$8&X(*(0E+V@)43
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M(6A:7JZ!R)V;,I#OEY2*W8T:H#DCF_\'4$L#!!0    ( -*#>U=:=+]1: 4
M (XD   9    >&PO=V]R:W-H965T<R]S:&5E=#,U+GAM;+6:75/C-A2&_XHF
M93J[,]O$EO,%A<PLL6GI0,M M[W8Z86P1>)9VTHE)8&9_OA*MK$CK]#B]G!#
M8D?GD?P>H:,WT>F>\2]B3:E$CWE6B+/!6LK-R6@DXC7-B1BR#2W4)P^,YT2J
M2[X:B0VG)"F#\FR$/6\ZRDE:#!:GY;T;OCAE6YFE!;WA2&SSG/"G<YJQ_=G
M'SS?N$U7:ZEOC!:G&[*B=U1^VMQP=35J*$F:TT*DK$"</IP-/OHG$0YT0-GB
MCY3NQ<%[I!_EGK$O^N(R.1MX>D0TH['4"*)>=G1)LTR3U#C^KJ&#ID\=>/C^
MF7Y1/KQZF'LBZ))E?Z:)7)\-Y@.4T >RS>0MV_],ZP>::%[,,E'^1?NJ[60V
M0/%62);7P6H$>5I4K^2Q%N(@8.Z]$(#K -P)\,<O! 1U0/#:@'$=,'YMP*0.
M*!]]5#U[*5Q()%F<<K9'7+=6-/VF5+^,5GJEA9XH=Y*K3U,5)Q>71<QRBGXG
MCU2@=R&5),T$^I5P3G0&WZ,?T*>[$+T[>H^.4%J@ZS3+5(+%Z4BJWC5C%-<]
MG5<]X1=Z\C&Z9H5<"Q05"4U,P$@-NQD[?A[[.782[^AFB +O \(>#BP#6KX^
M'%O"P]>'^Y;PZ-7A_L0A1M D,BAYP0N\WS94IZQ8H2LF!%JJ##ZI=61/>"+0
MYRO5&EU*FHN_;)FKT&,[6J]5)V)#8GHV4(N1H'Q'!XOOO_.GWH\VU2%A(20L
M H(9^1DW^1F[Z ?YR71^XL/\V%+BI/5-"20LK&!^-;%U(=HM\%!-X=VAU$ ]
M&E)/&JDGO:5&S?\"?=RD^F-5I9XHX3;MW7CL!5.;R,ZHOB)#PB(@F)&,:9.,
MJ5.M6T4D/%XC4B0HI#NU-=FHC89$DCRBF-,DE=;Y/[7-LIDYRY;61MAL%#K'
MUU=*()@AY:R1<O9Z*1.[E"_.:3=:U;!CVYQV1O6=TY"P" AF)&+>)&+N5.LG
MKM<5M1VE7*E>RD^$H-*F^_SK*3KK3M&EL[N^,D/"(B"8(?-Q(_/Q_YWOWZZC
MSB[ZUE%(6%C!_.!@9GC#>:>. O5HZ.][K3GPG!D(J9)9V3"]\]^1;%N539(I
M>TF*F%I-@)/85W!06EC3#,F#8="1'*I/4_,#0^8[-;^@B=J^9.CS-<WO*;?N
MU]V(WB)#TD)06@1%,Y.!VV3@MW-5-1LJ2Y"T$)060=',++76UW<ZM][>JL89
M1=G'T^Y*L'QN%QCM@N&XL\.T\X9^=V&Q-,.3@R7??/S66?K_W5JJNBEBGF[T
MPFV5PHT^"F;#&<JK+WW07KVB>[I2U4"RRDB5I4'M'B=ED3Z:SX?3IGE,"M6Z
M'$^JMDGUD%2 VCFE12II]F2=Z*!N%9060=',3+?&UG=;SSM))"V5OF*QJA&_
M;'DJDK3ZSM59,"#]Y!*4%H+2(BB:F:'6[?K3-RP8D%9U"4H+06D1%,W,4FND
M?;?=[5TP9I8%?CJ<=NO%S%(OOG)[H7MPO:5\"R?LMU;8=WOA"\9INBKT+PCH
MXU:N&4_EDWLM@C2H2U!:"$J+H&AF:EK[[!^_X5H$:IQ!:2$H+8*BF;]AM1X;
MNSUVW[4(6TRLVFP>=]8B:S.ONV2%[L'UE1**9DK96F?\#>OL7(O0/^JFD,I;
MI^0#"EF6$6Y7&-1=@])"4%H$13/SU;IK_(;N&H.Z:U!:"$J+H&AFEEIWC6'=
M-;;97*_KAI>V9OZXNXZ%[L'UEA+T)^#1P;F+G/)5>>!%*<2VA:R.,31WFT,U
M'\NC))W[Y_Y)6!V-:3'529UKPI7=%BBC#PKI#6?*WO#J\$MU(=FF/-UQSZ1D
M>?EV34E"N6Z@/G]@3#Y?Z Z:(TB+?P%02P,$%     @ TH-[5VV-E-I* P
MRA0   T   !X;"]S='EL97,N>&ULW5A=;]HP%/TK4;I.K30U0-I 5D#:D"I-
MVJ9*[</>*D,<L.38F6,ZV*^?KQW"1WT1Z\,*"VICW^-S[K%]0]SV*[WD]&%&
MJ0X6!1?5()QI77Z,HFHRHP6IKF1)A4%RJ0JB35=-HZI4E&05D H>=5JM)"H(
M$^&P+^;%7:&K8"+G0@_";A,*W.U+-@C;R748.+F1S.@@?+IX_W,N]>V[P-W/
M/IR=M9XN;W?C%Q:X#".OZ,T!HE>M%BX,(":>'":^3QN3[FY+V^'G1L@1SS%:
MST,S6=9,Z&#D]*#I[)D-(MQM>5UM>++$J"Z383^78ETM<>@"1ID4-'@F?!".
M"&=CQ8"5DX+QI0MW(#"17*I FS(UJ=H0J7X[N.UZ4,&U3L&$5#:WR^!^C^OA
M.\"J!P89YXW!3N@"PWY)M*9*W)F.'6R#+Z"@;C\N2^-PJLBRW;D)UP1[,TG&
M4F54-6G:X2HT['.:@QW%IC.X:UE& &HM"]/(&)E*0:R'%:-N&-D)Y?P!'N\?
M^9;V(M_8,[MCHFD:0W73R;@.Z&^J.>U-V>M7Z08E>Y;Z\]Q,1]@^%!F]5S1G
M"]M?Y(T!3+V-JY.RY,M/G$U%0=WD#TXX[),5+YA)Q7Z;;% J$Q.@*@R>J=)L
MLAGYI4CY2!=Z54Z+'/?<.4'/_W:=IU101?BF:5/[Q[S*KW9<OP_?PK/]6MEU
M[#49=X_?8WT&.':3R2F8/('MCM/C]UB?TX[=Y"FL9/?-OMGWFHSJD]#&<6OK
ML-5$ SC4#L+O<#SFZZ3!>,ZX9J+NS5B64?'BS&7D-1F;/]2V],WXC.9DSO5C
M P["=?L;S=B\2)M1][ 0]:AU^RM,KYTT)VJ3BXF,+F@VJKMJ.K;-P#1,UOH"
MPBYR9R\_@G$<YD< P_)@#C".8V%Y_J?Y]-#Y. SSUO,B/9330SF.Y4-&]H/E
M\7-2<_EGFJ9QG"38BHY&7@<C;-V2!'[\:I@W8&!Y(-/?K36^VWB%[*\#;$_W
M50@V4[P2L9GB:PV(?]V D:;^W<;R  /;!:QV(+\_#]24GQ/'L*N8-^P)QI$T
MQ1"H17^-)@FR.@E\_/N#/25QG*9^!#"_@SC&$'@:<01S !XP)([M>W#G?12M
MWE/1^K^7PS]02P,$%     @ TH-[5Y>*NQS     $P(   L   !?<F5L<R\N
M<F5L<YV2N6[#, Q ?\70GC 'T"&(,V7Q%@3Y 5:B#]@2!8I%G;^OVJ5QD L9
M>3T\$MP>:4#M.*2VBZD8_1!2:5K5N %(MB6/:<Z10J[4+!XUA]) 1-MC0[!:
M+#Y +AEFM[UD%J=SI%>(7->=I3W;+T]!;X"O.DQQ0FE(2S,.\,W2?S+W\PPU
M1>5*(Y5;&GC3Y?YVX$G1H2)8%II%R=.B':5_'<?VD-/IKV,BM'I;Z/EQ:%0*
MCMQC)8QQ8K3^-8+)#^Q^ %!+ P04    " #2@WM7$?_P\# #  #%%P  #P
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M4$L! A0#%     @ TH-[5P=!36*!    L0   !               ( !
M &1O8U!R;W!S+V%P<"YX;6Q02P$"% ,4    " #2@WM7URQG^^T    K @
M$0              @ &O    9&]C4')O<',O8V]R92YX;6Q02P$"% ,4
M" #2@WM7F5R<(Q &  "<)P  $P              @ '+ 0  >&PO=&AE;64O
M=&AE;64Q+GAM;%!+ 0(4 Q0    ( -*#>U>4^NTGT@<  %8T   8
M      " @0P(  !X;"]W;W)K<VAE971S+W-H965T,2YX;6Q02P$"% ,4
M" #2@WM7;O!M:8L$  !V$   &               @($4$   >&PO=V]R:W-H
M965T<R]S:&5E=#(N>&UL4$L! A0#%     @ TH-[5\FN5>JX @  =0@  !@
M             ("!U10  'AL+W=O<FMS:&5E=',O<VAE970S+GAM;%!+ 0(4
M Q0    ( -*#>U<PE#-YA@0   @2   8              " @<,7  !X;"]W
M;W)K<VAE971S+W-H965T-"YX;6Q02P$"% ,4    " #2@WM7IUO&R?\"  !B
M"0  &               @(%_'   >&PO=V]R:W-H965T<R]S:&5E=#4N>&UL
M4$L! A0#%     @ TH-[5X"LL.$F!@  ,QL  !@              ("!M!\
M 'AL+W=O<FMS:&5E=',O<VAE970V+GAM;%!+ 0(4 Q0    ( -*#>U>N(81$
M,0@  *4Z   8              " @1 F  !X;"]W;W)K<VAE971S+W-H965T
M-RYX;6Q02P$"% ,4    " #2@WM78G$Z6!<'  !:$   &
M@(%W+@  >&PO=V]R:W-H965T<R]S:&5E=#@N>&UL4$L! A0#%     @ TH-[
M5^]6\%R3'   P5,  !@              ("!Q#4  'AL+W=O<FMS:&5E=',O
M<VAE970Y+GAM;%!+ 0(4 Q0    ( -*#>U?5>"2?OP(  %\&   9
M      " @8U2  !X;"]W;W)K<VAE971S+W-H965T,3 N>&UL4$L! A0#%
M  @ TH-[5[,\-*0 !@  E0X  !D              ("!@U4  'AL+W=O<FMS
M:&5E=',O<VAE970Q,2YX;6Q02P$"% ,4    " #2@WM7\B&U>2L'  !3$@
M&0              @(&Z6P  >&PO=V]R:W-H965T<R]S:&5E=#$R+GAM;%!+
M 0(4 Q0    ( -*#>U?F9DY6P@L  $\>   9              " @1QC  !X
M;"]W;W)K<VAE971S+W-H965T,3,N>&UL4$L! A0#%     @ TH-[5R!Q0+Y)
M"@  "QD  !D              ("!%6\  'AL+W=O<FMS:&5E=',O<VAE970Q
M-"YX;6Q02P$"% ,4    " #2@WM7'7?%L@L#   !!P  &0
M@(&5>0  >&PO=V]R:W-H965T<R]S:&5E=#$U+GAM;%!+ 0(4 Q0    ( -*#
M>U<V)9\LS1T  (]<   9              " @==\  !X;"]W;W)K<VAE971S
M+W-H965T,38N>&UL4$L! A0#%     @ TH-[5^AY;_>K @  )@8  !D
M         ("!VYH  'AL+W=O<FMS:&5E=',O<VAE970Q-RYX;6Q02P$"% ,4
M    " #2@WM7%N;E26H&  #1$0  &0              @(&]G0  >&PO=V]R
M:W-H965T<R]S:&5E=#$X+GAM;%!+ 0(4 Q0    ( -*#>U=<OIB!&04  &D,
M   9              " @5ZD  !X;"]W;W)K<VAE971S+W-H965T,3DN>&UL
M4$L! A0#%     @ TH-[5_@?O=?+ @  [@<  !D              ("!KJD
M 'AL+W=O<FMS:&5E=',O<VAE970R,"YX;6Q02P$"% ,4    " #2@WM7PQ50
MNL,"  !:"   &0              @(&PK   >&PO=V]R:W-H965T<R]S:&5E
M=#(Q+GAM;%!+ 0(4 Q0    ( -*#>U=0?)[+W0,  (82   9
M  " @:JO  !X;"]W;W)K<VAE971S+W-H965T,C(N>&UL4$L! A0#%     @
MTH-[5Q>*W)8."   +DL  !D              ("!OK,  'AL+W=O<FMS:&5E
M=',O<VAE970R,RYX;6Q02P$"% ,4    " #2@WM7F?2G&G8"  "B!@  &0
M            @($#O   >&PO=V]R:W-H965T<R]S:&5E=#(T+GAM;%!+ 0(4
M Q0    ( -*#>U=8_BGQ?0(  *P&   9              " @;"^  !X;"]W
M;W)K<VAE971S+W-H965T,C4N>&UL4$L! A0#%     @ TH-[5T=Y]C3X @
MK@H  !D              ("!9,$  'AL+W=O<FMS:&5E=',O<VAE970R-BYX
M;6Q02P$"% ,4    " #2@WM7JI_VU>$$  !V%@  &0              @(&3
MQ   >&PO=V]R:W-H965T<R]S:&5E=#(W+GAM;%!+ 0(4 Q0    ( -*#>U>/
MN*OA P@   -&   9              " @:O)  !X;"]W;W)K<VAE971S+W-H
M965T,C@N>&UL4$L! A0#%     @ TH-[5[78R.E" P  @0T  !D
M     ("!Y=$  'AL+W=O<FMS:&5E=',O<VAE970R.2YX;6Q02P$"% ,4
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M+GAM;%!+ 0(4 Q0    ( -*#>U>5ZT"^T@0  "\3   9              "
M@6#E  !X;"]W;W)K<VAE971S+W-H965T,S0N>&UL4$L! A0#%     @ TH-[
M5UITOU%H!0  CB0  !D              ("!:>H  'AL+W=O<FMS:&5E=',O
M<VAE970S-2YX;6Q02P$"% ,4    " #2@WM7;8V4VDH#  #*%   #0
M        @ $(\   >&PO<W1Y;&5S+GAM;%!+ 0(4 Q0    ( -*#>U>7BKL<
MP    !,"   +              "  7WS  !?<F5L<R\N<F5L<U!+ 0(4 Q0
M   ( -*#>U<1__#P, ,  ,47   /              "  6;T  !X;"]W;W)K
M8F]O:RYX;6Q02P$"% ,4    " #2@WM72XJ@"W,!  !P%0  &@
M    @ '#]P  >&PO7W)E;',O=V]R:V)O;VLN>&UL+G)E;'-02P$"% ,4
M" #2@WM7WR$G&Y(!  #Y%0  $P              @ %N^0  6T-O;G1E;G1?
@5'EP97-=+GAM;%!+!08     *P K *0+   Q^P     !

end
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>54
<FILENAME>Show.js
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
// Edgar(tm) Renderer was created by staff of the U.S. Securities and Exchange Commission.  Data and content created by government employees within the scope of their employment are not subject to domestic copyright protection. 17 U.S.C. 105.
var Show={};Show.LastAR=null,Show.showAR=function(a,r,w){if(Show.LastAR)Show.hideAR();var e=a;while(e&&e.nodeName!='TABLE')e=e.nextSibling;if(!e||e.nodeName!='TABLE'){var ref=((window)?w.document:document).getElementById(r);if(ref){e=ref.cloneNode(!0);
e.removeAttribute('id');a.parentNode.appendChild(e)}}
if(e)e.style.display='block';Show.LastAR=e};Show.hideAR=function(){Show.LastAR.style.display='none'};Show.toggleNext=function(a){var e=a;while(e.nodeName!='DIV')e=e.nextSibling;if(!e.style){}else if(!e.style.display){}else{var d,p_;if(e.style.display=='none'){d='block';p='-'}else{d='none';p='+'}
e.style.display=d;if(a.textContent){a.textContent=p+a.textContent.substring(1)}else{a.innerText=p+a.innerText.substring(1)}}}
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>55
<FILENAME>report.css
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
/* Updated 2009-11-04 */
/* v2.2.0.24 */

/* DefRef Styles */
..report table.authRefData{
	background-color: #def;
	border: 2px solid #2F4497;
	font-size: 1em;
	position: absolute;
}

..report table.authRefData a {
	display: block;
	font-weight: bold;
}

..report table.authRefData p {
	margin-top: 0px;
}

..report table.authRefData .hide {
	background-color: #2F4497;
	padding: 1px 3px 0px 0px;
	text-align: right;
}

..report table.authRefData .hide a:hover {
	background-color: #2F4497;
}

..report table.authRefData .body {
	height: 150px;
	overflow: auto;
	width: 400px;
}

..report table.authRefData table{
	font-size: 1em;
}

/* Report Styles */
..pl a, .pl a:visited {
	color: black;
	text-decoration: none;
}

/* table */
..report {
	background-color: white;
	border: 2px solid #acf;
	clear: both;
	color: black;
	font: normal 8pt Helvetica, Arial, san-serif;
	margin-bottom: 2em;
}

..report hr {
	border: 1px solid #acf;
}

/* Top labels */
..report th {
	background-color: #acf;
	color: black;
	font-weight: bold;
	text-align: center;
}

..report th.void	{
	background-color: transparent;
	color: #000000;
	font: bold 10pt Helvetica, Arial, san-serif;
	text-align: left;
}

..report .pl {
	text-align: left;
	vertical-align: top;
	white-space: normal;
	width: 200px;
	white-space: normal; /* word-wrap: break-word; */
}

..report td.pl a.a {
	cursor: pointer;
	display: block;
	width: 200px;
	overflow: hidden;
}

..report td.pl div.a {
	width: 200px;
}

..report td.pl a:hover {
	background-color: #ffc;
}

/* Header rows... */
..report tr.rh {
	background-color: #acf;
	color: black;
	font-weight: bold;
}

/* Calendars... */
..report .rc {
	background-color: #f0f0f0;
}

/* Even rows... */
..report .re, .report .reu {
	background-color: #def;
}

..report .reu td {
	border-bottom: 1px solid black;
}

/* Odd rows... */
..report .ro, .report .rou {
	background-color: white;
}

..report .rou td {
	border-bottom: 1px solid black;
}

..report .rou table td, .report .reu table td {
	border-bottom: 0px solid black;
}

/* styles for footnote marker */
..report .fn {
	white-space: nowrap;
}

/* styles for numeric types */
..report .num, .report .nump {
	text-align: right;
	white-space: nowrap;
}

..report .nump {
	padding-left: 2em;
}

..report .nump {
	padding: 0px 0.4em 0px 2em;
}

/* styles for text types */
..report .text {
	text-align: left;
	white-space: normal;
}

..report .text .big {
	margin-bottom: 1em;
	width: 17em;
}

..report .text .more {
	display: none;
}

..report .text .note {
	font-style: italic;
	font-weight: bold;
}

..report .text .small {
	width: 10em;
}

..report sup {
	font-style: italic;
}

..report .outerFootnotes {
	font-size: 1em;
}
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>56
<FILENAME>FilingSummary.xml
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<XML>
<?xml version='1.0' encoding='utf-8'?>
<FilingSummary>
  <Version>3.23.3</Version>
  <ProcessingTime/>
  <ReportFormat>html</ReportFormat>
  <ContextCount>96</ContextCount>
  <ElementCount>250</ElementCount>
  <EntityCount>1</EntityCount>
  <FootnotesReported>false</FootnotesReported>
  <SegmentCount>30</SegmentCount>
  <ScenarioCount>0</ScenarioCount>
  <TuplesReported>false</TuplesReported>
  <UnitCount>4</UnitCount>
  <MyReports>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R1.htm</HtmlFileName>
      <LongName>00000001 - Document - Cover</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/Cover</Role>
      <ShortName>Cover</ShortName>
      <MenuCategory>Cover</MenuCategory>
      <Position>1</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R2.htm</HtmlFileName>
      <LongName>00000002 - Statement - Consolidated Balance Sheets</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/BalanceSheets</Role>
      <ShortName>Consolidated Balance Sheets</ShortName>
      <MenuCategory>Statements</MenuCategory>
      <Position>2</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R3.htm</HtmlFileName>
      <LongName>00000003 - Statement - Consolidated Balance Sheets (Parenthetical)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/BalanceSheetsParenthetical</Role>
      <ShortName>Consolidated Balance Sheets (Parenthetical)</ShortName>
      <MenuCategory>Statements</MenuCategory>
      <Position>3</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R4.htm</HtmlFileName>
      <LongName>00000004 - Statement - Consolidated Statements of Operations and Comprehensive Loss</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss</Role>
      <ShortName>Consolidated Statements of Operations and Comprehensive Loss</ShortName>
      <MenuCategory>Statements</MenuCategory>
      <Position>4</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R5.htm</HtmlFileName>
      <LongName>00000005 - Statement - Consolidated Statements of Operations and Comprehensive Loss (Parenthetical)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/StatementsOfOperationsAndComprehensiveLossParenthetical</Role>
      <ShortName>Consolidated Statements of Operations and Comprehensive Loss (Parenthetical)</ShortName>
      <MenuCategory>Statements</MenuCategory>
      <Position>5</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R6.htm</HtmlFileName>
      <LongName>00000006 - Statement - Consolidated Statements of Cash Flows</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/StatementsOfCashFlows</Role>
      <ShortName>Consolidated Statements of Cash Flows</ShortName>
      <MenuCategory>Statements</MenuCategory>
      <Position>6</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R7.htm</HtmlFileName>
      <LongName>00000007 - Statement - Consolidated Statements of Changes in Stockholders' Equity</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/StatementsOfChangesInStockholdersEquity</Role>
      <ShortName>Consolidated Statements of Changes in Stockholders' Equity</ShortName>
      <MenuCategory>Statements</MenuCategory>
      <Position>7</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R8.htm</HtmlFileName>
      <LongName>00000008 - Disclosure - Business Description and Basis of Presentation</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/BusinessDescriptionAndBasisOfPresentation</Role>
      <ShortName>Business Description and Basis of Presentation</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>8</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R9.htm</HtmlFileName>
      <LongName>00000009 - Disclosure - Summary of Significant Accounting Policies</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/SummaryOfSignificantAccountingPolicies</Role>
      <ShortName>Summary of Significant Accounting Policies</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>9</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R10.htm</HtmlFileName>
      <LongName>00000010 - Disclosure - Accrued Liabilities</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/AccruedLiabilities</Role>
      <ShortName>Accrued Liabilities</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>10</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R11.htm</HtmlFileName>
      <LongName>00000011 - Disclosure - Other Income</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/OtherIncome</Role>
      <ShortName>Other Income</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>11</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R12.htm</HtmlFileName>
      <LongName>00000012 - Disclosure - Equity Offerings</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/EquityOfferings</Role>
      <ShortName>Equity Offerings</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>12</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R13.htm</HtmlFileName>
      <LongName>00000013 - Disclosure - Commitments and Contingencies</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/CommitmentsAndContingencies</Role>
      <ShortName>Commitments and Contingencies</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>13</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R14.htm</HtmlFileName>
      <LongName>00000014 - Disclosure - Income Taxes</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/IncomeTaxes</Role>
      <ShortName>Income Taxes</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>14</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R15.htm</HtmlFileName>
      <LongName>00000015 - Disclosure - Subsequent Events</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/SubsequentEvents</Role>
      <ShortName>Subsequent Events</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>15</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R16.htm</HtmlFileName>
      <LongName>00000016 - Disclosure - Summary of Significant Accounting Policies (Policies)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies</Role>
      <ShortName>Summary of Significant Accounting Policies (Policies)</ShortName>
      <MenuCategory>Policies</MenuCategory>
      <ParentRole>http://anavex.com/role/SummaryOfSignificantAccountingPolicies</ParentRole>
      <Position>16</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R17.htm</HtmlFileName>
      <LongName>00000017 - Disclosure - Accrued Liabilities (Tables)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/AccruedLiabilitiesTables</Role>
      <ShortName>Accrued Liabilities (Tables)</ShortName>
      <MenuCategory>Tables</MenuCategory>
      <ParentRole>http://anavex.com/role/AccruedLiabilities</ParentRole>
      <Position>17</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R18.htm</HtmlFileName>
      <LongName>00000018 - Disclosure - Commitments and Contingencies (Tables)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/CommitmentsAndContingenciesTables</Role>
      <ShortName>Commitments and Contingencies (Tables)</ShortName>
      <MenuCategory>Tables</MenuCategory>
      <ParentRole>http://anavex.com/role/CommitmentsAndContingencies</ParentRole>
      <Position>18</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R19.htm</HtmlFileName>
      <LongName>00000019 - Disclosure - Income Taxes (Tables)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/IncomeTaxesTables</Role>
      <ShortName>Income Taxes (Tables)</ShortName>
      <MenuCategory>Tables</MenuCategory>
      <ParentRole>http://anavex.com/role/IncomeTaxes</ParentRole>
      <Position>19</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R20.htm</HtmlFileName>
      <LongName>00000020 - Disclosure - Summary of Significant Accounting Policies (Details Narrative)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/SummaryOfSignificantAccountingPoliciesDetailsNarrative</Role>
      <ShortName>Summary of Significant Accounting Policies (Details Narrative)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies</ParentRole>
      <Position>20</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R21.htm</HtmlFileName>
      <LongName>00000021 - Disclosure - Accrued Liabilities (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/AccruedLiabilitiesDetails</Role>
      <ShortName>Accrued Liabilities (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/AccruedLiabilitiesTables</ParentRole>
      <Position>21</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R22.htm</HtmlFileName>
      <LongName>00000022 - Disclosure - Other Income (Details Narrative)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/OtherIncomeDetailsNarrative</Role>
      <ShortName>Other Income (Details Narrative)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/OtherIncome</ParentRole>
      <Position>22</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R23.htm</HtmlFileName>
      <LongName>00000023 - Disclosure - Equity Offerings (Details Narrative)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/EquityOfferingsDetailsNarrative</Role>
      <ShortName>Equity Offerings (Details Narrative)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/EquityOfferings</ParentRole>
      <Position>23</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R24.htm</HtmlFileName>
      <LongName>00000024 - Disclosure - Commitments and Contingencies (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/CommitmentsAndContingenciesDetails</Role>
      <ShortName>Commitments and Contingencies (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/CommitmentsAndContingenciesTables</ParentRole>
      <Position>24</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R25.htm</HtmlFileName>
      <LongName>00000025 - Disclosure - Commitments and Contingencies (Details 1)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/CommitmentsAndContingenciesDetails1</Role>
      <ShortName>Commitments and Contingencies (Details 1)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/CommitmentsAndContingenciesTables</ParentRole>
      <Position>25</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R26.htm</HtmlFileName>
      <LongName>00000026 - Disclosure - Commitments and Contingencies (Details 2)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/CommitmentsAndContingenciesDetails2</Role>
      <ShortName>Commitments and Contingencies (Details 2)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/CommitmentsAndContingenciesTables</ParentRole>
      <Position>26</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R27.htm</HtmlFileName>
      <LongName>00000027 - Disclosure - Commitments and Contingencies (Details 3)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/CommitmentsAndContingenciesDetails3</Role>
      <ShortName>Commitments and Contingencies (Details 3)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/CommitmentsAndContingenciesTables</ParentRole>
      <Position>27</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R28.htm</HtmlFileName>
      <LongName>00000028 - Disclosure - Commitments and Contingencies (Details 4)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/CommitmentsAndContingenciesDetails4</Role>
      <ShortName>Commitments and Contingencies (Details 4)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/CommitmentsAndContingenciesTables</ParentRole>
      <Position>28</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R29.htm</HtmlFileName>
      <LongName>00000029 - Disclosure - Commitments and Contingencies (Details 5)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/CommitmentsAndContingenciesDetails5</Role>
      <ShortName>Commitments and Contingencies (Details 5)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/CommitmentsAndContingenciesTables</ParentRole>
      <Position>29</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R30.htm</HtmlFileName>
      <LongName>00000030 - Disclosure - Commitments and Contingencies (Details 6)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/CommitmentsAndContingenciesDetails6</Role>
      <ShortName>Commitments and Contingencies (Details 6)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/CommitmentsAndContingenciesTables</ParentRole>
      <Position>30</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R31.htm</HtmlFileName>
      <LongName>00000031 - Disclosure - Commitments and Contingencies (Details Narrative)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative</Role>
      <ShortName>Commitments and Contingencies (Details Narrative)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/CommitmentsAndContingenciesTables</ParentRole>
      <Position>31</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R32.htm</HtmlFileName>
      <LongName>00000032 - Disclosure - Income Taxes (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/IncomeTaxesDetails</Role>
      <ShortName>Income Taxes (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/IncomeTaxesTables</ParentRole>
      <Position>32</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R33.htm</HtmlFileName>
      <LongName>00000033 - Disclosure - Income Taxes (Details 1)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/IncomeTaxesDetails1</Role>
      <ShortName>Income Taxes (Details 1)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/IncomeTaxesTables</ParentRole>
      <Position>33</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R34.htm</HtmlFileName>
      <LongName>00000034 - Disclosure - Income Taxes (Details 2)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/IncomeTaxesDetails2</Role>
      <ShortName>Income Taxes (Details 2)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/IncomeTaxesTables</ParentRole>
      <Position>34</Position>
    </Report>
    <Report instance="e5240_10k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R35.htm</HtmlFileName>
      <LongName>00000035 - Disclosure - Income Taxes (Details Narrative)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://anavex.com/role/IncomeTaxesDetailsNarrative</Role>
      <ShortName>Income Taxes (Details Narrative)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://anavex.com/role/IncomeTaxesTables</ParentRole>
      <Position>35</Position>
    </Report>
    <Report>
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <LongName>All Reports</LongName>
      <ReportType>Book</ReportType>
      <ShortName>All Reports</ShortName>
    </Report>
  </MyReports>
  <InputFiles>
    <File>avxl-20230930.xsd</File>
    <File>avxl-20230930_cal.xml</File>
    <File>avxl-20230930_def.xml</File>
    <File>avxl-20230930_lab.xml</File>
    <File>avxl-20230930_pre.xml</File>
    <File doctype="10-K" isDefinitelyFs="true" isUsgaap="true" original="e5240_10k.htm">e5240_10k.htm</File>
  </InputFiles>
  <SupplementalFiles>
    <File>image_001.gif</File>
    <File>image_002.gif</File>
  </SupplementalFiles>
  <BaseTaxonomies>
    <BaseTaxonomy items="460">http://fasb.org/us-gaap/2023</BaseTaxonomy>
    <BaseTaxonomy items="39">http://xbrl.sec.gov/dei/2023</BaseTaxonomy>
  </BaseTaxonomies>
  <HasPresentationLinkbase>true</HasPresentationLinkbase>
  <HasCalculationLinkbase>true</HasCalculationLinkbase>
</FilingSummary>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>JSON
<SEQUENCE>58
<FILENAME>MetaLinks.json
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
{
 "version": "2.2",
 "instance": {
  "e5240_10k.htm": {
   "nsprefix": "avxl",
   "nsuri": "http://anavex.com/20230930",
   "dts": {
    "schema": {
     "local": [
      "avxl-20230930.xsd"
     ],
     "remote": [
      "http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd",
      "http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd",
      "http://www.xbrl.org/2003/xl-2003-12-31.xsd",
      "http://www.xbrl.org/2003/xlink-2003-12-31.xsd",
      "http://www.xbrl.org/2005/xbrldt-2005.xsd",
      "http://www.xbrl.org/2006/ref-2006-02-27.xsd",
      "http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd",
      "http://www.xbrl.org/lrr/role/net-2009-12-16.xsd",
      "http://www.xbrl.org/lrr/role/reference-2009-12-16.xsd",
      "https://www.xbrl.org/2020/extensible-enumerations-2.0.xsd",
      "https://www.xbrl.org/dtr/type/2020-01-21/types.xsd",
      "https://www.xbrl.org/dtr/type/2022-03-31/types.xsd",
      "https://xbrl.fasb.org/srt/2023/elts/srt-2023.xsd",
      "https://xbrl.fasb.org/srt/2023/elts/srt-roles-2023.xsd",
      "https://xbrl.fasb.org/srt/2023/elts/srt-types-2023.xsd",
      "https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd",
      "https://xbrl.fasb.org/us-gaap/2023/elts/us-roles-2023.xsd",
      "https://xbrl.fasb.org/us-gaap/2023/elts/us-types-2023.xsd",
      "https://xbrl.sec.gov/country/2023/country-2023.xsd",
      "https://xbrl.sec.gov/currency/2023/currency-2023.xsd",
      "https://xbrl.sec.gov/dei/2023/dei-2023.xsd"
     ]
    },
    "calculationLink": {
     "local": [
      "avxl-20230930_cal.xml"
     ]
    },
    "definitionLink": {
     "local": [
      "avxl-20230930_def.xml"
     ]
    },
    "labelLink": {
     "local": [
      "avxl-20230930_lab.xml"
     ]
    },
    "presentationLink": {
     "local": [
      "avxl-20230930_pre.xml"
     ]
    },
    "inline": {
     "local": [
      "e5240_10k.htm"
     ]
    }
   },
   "keyStandard": 197,
   "keyCustom": 53,
   "axisStandard": 12,
   "axisCustom": 0,
   "memberStandard": 9,
   "memberCustom": 20,
   "hidden": {
    "total": 73,
    "http://fasb.org/us-gaap/2023": 33,
    "http://anavex.com/20230930": 36,
    "http://xbrl.sec.gov/dei/2023": 4
   },
   "contextCount": 96,
   "entityCount": 1,
   "segmentCount": 30,
   "elementCount": 365,
   "unitCount": 4,
   "baseTaxonomies": {
    "http://xbrl.sec.gov/dei/2023": 39,
    "http://fasb.org/us-gaap/2023": 460
   },
   "report": {
    "R1": {
     "role": "http://anavex.com/role/Cover",
     "longName": "00000001 - Document - Cover",
     "shortName": "Cover",
     "isDefault": "true",
     "groupType": "document",
     "subGroupType": "",
     "menuCat": "Cover",
     "order": "1",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "dei:DocumentType",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "span",
       "b",
       "span",
       "p",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "dei:DocumentType",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "span",
       "b",
       "span",
       "p",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R2": {
     "role": "http://anavex.com/role/BalanceSheets",
     "longName": "00000002 - Statement - Consolidated Balance Sheets",
     "shortName": "Consolidated Balance Sheets",
     "isDefault": "false",
     "groupType": "statement",
     "subGroupType": "",
     "menuCat": "Statements",
     "order": "2",
     "firstAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "us-gaap:CashAndCashEquivalentsAtCarryingValue",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "us-gaap:CashAndCashEquivalentsAtCarryingValue",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R3": {
     "role": "http://anavex.com/role/BalanceSheetsParenthetical",
     "longName": "00000003 - Statement - Consolidated Balance Sheets (Parenthetical)",
     "shortName": "Consolidated Balance Sheets (Parenthetical)",
     "isDefault": "false",
     "groupType": "statement",
     "subGroupType": "parenthetical",
     "menuCat": "Statements",
     "order": "3",
     "firstAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "us-gaap:PreferredStockSharesAuthorized",
      "unitRef": "Shares",
      "xsiNil": "false",
      "lang": null,
      "decimals": "INF",
      "ancestors": [
       "span",
       "span",
       "td",
       "tr",
       "table",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "us-gaap:PreferredStockSharesAuthorized",
      "unitRef": "Shares",
      "xsiNil": "false",
      "lang": null,
      "decimals": "INF",
      "ancestors": [
       "span",
       "span",
       "td",
       "tr",
       "table",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R4": {
     "role": "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss",
     "longName": "00000004 - Statement - Consolidated Statements of Operations and Comprehensive Loss",
     "shortName": "Consolidated Statements of Operations and Comprehensive Loss",
     "isDefault": "false",
     "groupType": "statement",
     "subGroupType": "",
     "menuCat": "Statements",
     "order": "4",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:GeneralAndAdministrativeExpense",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:GeneralAndAdministrativeExpense",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R5": {
     "role": "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLossParenthetical",
     "longName": "00000005 - Statement - Consolidated Statements of Operations and Comprehensive Loss (Parenthetical)",
     "shortName": "Consolidated Statements of Operations and Comprehensive Loss (Parenthetical)",
     "isDefault": "false",
     "groupType": "statement",
     "subGroupType": "parenthetical",
     "menuCat": "Statements",
     "order": "5",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:EarningsPerShareBasic",
      "unitRef": "USDPShares",
      "xsiNil": "false",
      "lang": null,
      "decimals": "INF",
      "ancestors": [
       "span",
       "span",
       "span",
       "td",
       "tr",
       "table",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:EarningsPerShareBasic",
      "unitRef": "USDPShares",
      "xsiNil": "false",
      "lang": null,
      "decimals": "INF",
      "ancestors": [
       "span",
       "span",
       "span",
       "td",
       "tr",
       "table",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R6": {
     "role": "http://anavex.com/role/StatementsOfCashFlows",
     "longName": "00000006 - Statement - Consolidated Statements of Cash Flows",
     "shortName": "Consolidated Statements of Cash Flows",
     "isDefault": "false",
     "groupType": "statement",
     "subGroupType": "",
     "menuCat": "Statements",
     "order": "6",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:NetIncomeLoss",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "avxl:NoncashFinancingRelatedCharges",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "unique": true
     }
    },
    "R7": {
     "role": "http://anavex.com/role/StatementsOfChangesInStockholdersEquity",
     "longName": "00000007 - Statement - Consolidated Statements of Changes in Stockholders' Equity",
     "shortName": "Consolidated Statements of Changes in Stockholders' Equity",
     "isDefault": "false",
     "groupType": "statement",
     "subGroupType": "",
     "menuCat": "Statements",
     "order": "7",
     "firstAnchor": {
      "contextRef": "AsOf2020-09-30_us-gaap_CommonStockMember",
      "name": "us-gaap:StockholdersEquity",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "AsOf2020-09-30_us-gaap_CommonStockMember",
      "name": "us-gaap:StockholdersEquity",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R8": {
     "role": "http://anavex.com/role/BusinessDescriptionAndBasisOfPresentation",
     "longName": "00000008 - Disclosure - Business Description and Basis of Presentation",
     "shortName": "Business Description and Basis of Presentation",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "",
     "menuCat": "Notes",
     "order": "8",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R9": {
     "role": "http://anavex.com/role/SummaryOfSignificantAccountingPolicies",
     "longName": "00000009 - Disclosure - Summary of Significant Accounting Policies",
     "shortName": "Summary of Significant Accounting Policies",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "",
     "menuCat": "Notes",
     "order": "9",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:SignificantAccountingPoliciesTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:SignificantAccountingPoliciesTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R10": {
     "role": "http://anavex.com/role/AccruedLiabilities",
     "longName": "00000010 - Disclosure - Accrued Liabilities",
     "shortName": "Accrued Liabilities",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "",
     "menuCat": "Notes",
     "order": "10",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "avxl:AccuredLiabilitiesTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "avxl:AccuredLiabilitiesTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R11": {
     "role": "http://anavex.com/role/OtherIncome",
     "longName": "00000011 - Disclosure - Other Income",
     "shortName": "Other Income",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "",
     "menuCat": "Notes",
     "order": "11",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "avxl:OtherIncomeDisclosureTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "avxl:OtherIncomeDisclosureTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R12": {
     "role": "http://anavex.com/role/EquityOfferings",
     "longName": "00000012 - Disclosure - Equity Offerings",
     "shortName": "Equity Offerings",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "",
     "menuCat": "Notes",
     "order": "12",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "avxl:EquityOfferingTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "avxl:EquityOfferingTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R13": {
     "role": "http://anavex.com/role/CommitmentsAndContingencies",
     "longName": "00000013 - Disclosure - Commitments and Contingencies",
     "shortName": "Commitments and Contingencies",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "",
     "menuCat": "Notes",
     "order": "13",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:CommitmentsDisclosureTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:CommitmentsDisclosureTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R14": {
     "role": "http://anavex.com/role/IncomeTaxes",
     "longName": "00000014 - Disclosure - Income Taxes",
     "shortName": "Income Taxes",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "",
     "menuCat": "Notes",
     "order": "14",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:IncomeTaxDisclosureTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:IncomeTaxDisclosureTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R15": {
     "role": "http://anavex.com/role/SubsequentEvents",
     "longName": "00000015 - Disclosure - Subsequent Events",
     "shortName": "Subsequent Events",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "",
     "menuCat": "Notes",
     "order": "15",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:SubsequentEventsTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:SubsequentEventsTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R16": {
     "role": "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies",
     "longName": "00000016 - Disclosure - Summary of Significant Accounting Policies (Policies)",
     "shortName": "Summary of Significant Accounting Policies (Policies)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "policies",
     "menuCat": "Policies",
     "order": "16",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:UseOfEstimates",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "us-gaap:SignificantAccountingPoliciesTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:UseOfEstimates",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "us-gaap:SignificantAccountingPoliciesTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R17": {
     "role": "http://anavex.com/role/AccruedLiabilitiesTables",
     "longName": "00000017 - Disclosure - Accrued Liabilities (Tables)",
     "shortName": "Accrued Liabilities (Tables)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "tables",
     "menuCat": "Tables",
     "order": "17",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:ScheduleOfAccruedLiabilitiesTableTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "avxl:AccuredLiabilitiesTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:ScheduleOfAccruedLiabilitiesTableTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "avxl:AccuredLiabilitiesTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R18": {
     "role": "http://anavex.com/role/CommitmentsAndContingenciesTables",
     "longName": "00000018 - Disclosure - Commitments and Contingencies (Tables)",
     "shortName": "Commitments and Contingencies (Tables)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "tables",
     "menuCat": "Tables",
     "order": "18",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:LeaseCostTableTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:LeaseCostTableTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R19": {
     "role": "http://anavex.com/role/IncomeTaxesTables",
     "longName": "00000019 - Disclosure - Income Taxes (Tables)",
     "shortName": "Income Taxes (Tables)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "tables",
     "menuCat": "Tables",
     "order": "19",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "us-gaap:IncomeTaxDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "us-gaap:IncomeTaxDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R20": {
     "role": "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesDetailsNarrative",
     "longName": "00000020 - Disclosure - Summary of Significant Accounting Policies (Details Narrative)",
     "shortName": "Summary of Significant Accounting Policies (Details Narrative)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "20",
     "firstAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "us-gaap:CashFDICInsuredAmount",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "0",
      "ancestors": [
       "span",
       "span",
       "p",
       "us-gaap:CashAndCashEquivalentsPolicyTextBlock",
       "us-gaap:SignificantAccountingPoliciesTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "us-gaap:CashFDICInsuredAmount",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "0",
      "ancestors": [
       "span",
       "span",
       "p",
       "us-gaap:CashAndCashEquivalentsPolicyTextBlock",
       "us-gaap:SignificantAccountingPoliciesTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R21": {
     "role": "http://anavex.com/role/AccruedLiabilitiesDetails",
     "longName": "00000021 - Disclosure - Accrued Liabilities (Details)",
     "shortName": "Accrued Liabilities (Details)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "21",
     "firstAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "avxl:AccruedClinicalSiteAndPatientVisitsCosts",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:ScheduleOfAccruedLiabilitiesTableTextBlock",
       "avxl:AccuredLiabilitiesTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "avxl:AccruedClinicalSiteAndPatientVisitsCosts",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:ScheduleOfAccruedLiabilitiesTableTextBlock",
       "avxl:AccuredLiabilitiesTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R22": {
     "role": "http://anavex.com/role/OtherIncomeDetailsNarrative",
     "longName": "00000022 - Disclosure - Other Income (Details Narrative)",
     "shortName": "Other Income (Details Narrative)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "22",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "avxl:GrantIncome",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-5",
      "ancestors": [
       "span",
       "span",
       "p",
       "avxl:OtherIncomeDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "avxl:GrantIncome",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-5",
      "ancestors": [
       "span",
       "span",
       "p",
       "avxl:OtherIncomeDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R23": {
     "role": "http://anavex.com/role/EquityOfferingsDetailsNarrative",
     "longName": "00000023 - Disclosure - Equity Offerings (Details Narrative)",
     "shortName": "Equity Offerings (Details Narrative)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "23",
     "firstAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "avxl:SalesOfAgreementAmount",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-5",
      "ancestors": [
       "span",
       "span",
       "p",
       "avxl:EquityOfferingTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "avxl:SalesOfAgreementAmount",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-5",
      "ancestors": [
       "span",
       "span",
       "p",
       "avxl:EquityOfferingTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R24": {
     "role": "http://anavex.com/role/CommitmentsAndContingenciesDetails",
     "longName": "00000024 - Disclosure - Commitments and Contingencies (Details)",
     "shortName": "Commitments and Contingencies (Details)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "24",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:OperatingLeaseCost",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:LeaseCostTableTextBlock",
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:OperatingLeaseCost",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:LeaseCostTableTextBlock",
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R25": {
     "role": "http://anavex.com/role/CommitmentsAndContingenciesDetails1",
     "longName": "00000025 - Disclosure - Commitments and Contingencies (Details 1)",
     "shortName": "Commitments and Contingencies (Details 1)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "25",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:PensionContributions",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:DefinedContributionPlanDisclosuresTableTextBlock",
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:PensionContributions",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:DefinedContributionPlanDisclosuresTableTextBlock",
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R26": {
     "role": "http://anavex.com/role/CommitmentsAndContingenciesDetails2",
     "longName": "00000026 - Disclosure - Commitments and Contingencies (Details 2)",
     "shortName": "Commitments and Contingencies (Details 2)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "26",
     "firstAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber",
      "unitRef": "Shares",
      "xsiNil": "false",
      "lang": null,
      "decimals": "INF",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "avxl:ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock",
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber",
      "unitRef": "Shares",
      "xsiNil": "false",
      "lang": null,
      "decimals": "INF",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "avxl:ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock",
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R27": {
     "role": "http://anavex.com/role/CommitmentsAndContingenciesDetails3",
     "longName": "00000027 - Disclosure - Commitments and Contingencies (Details 3)",
     "shortName": "Commitments and Contingencies (Details 3)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "27",
     "firstAnchor": {
      "contextRef": "AsOf2022-09-30_us-gaap_StockOptionMember",
      "name": "us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber",
      "unitRef": "Shares",
      "xsiNil": "false",
      "lang": null,
      "decimals": "INF",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:ScheduleOfStockOptionsRollForwardTableTextBlock",
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true
     },
     "uniqueAnchor": {
      "contextRef": "AsOf2021-09-30_us-gaap_StockOptionMember",
      "name": "us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "0",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:ScheduleOfStockOptionsRollForwardTableTextBlock",
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "unique": true
     }
    },
    "R28": {
     "role": "http://anavex.com/role/CommitmentsAndContingenciesDetails4",
     "longName": "00000028 - Disclosure - Commitments and Contingencies (Details 4)",
     "shortName": "Commitments and Contingencies (Details 4)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "28",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "span",
       "span",
       "p",
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-012023-09-30_us-gaap_StockOptionMember",
      "name": "us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "span",
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock",
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "unique": true
     }
    },
    "R29": {
     "role": "http://anavex.com/role/CommitmentsAndContingenciesDetails5",
     "longName": "00000029 - Disclosure - Commitments and Contingencies (Details 5)",
     "shortName": "Commitments and Contingencies (Details 5)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "29",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:ShareBasedCompensation",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-012023-09-30_us-gaap_GeneralAndAdministrativeExpenseMember",
      "name": "us-gaap:ShareBasedCompensation",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock",
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "unique": true
     }
    },
    "R30": {
     "role": "http://anavex.com/role/CommitmentsAndContingenciesDetails6",
     "longName": "00000030 - Disclosure - Commitments and Contingencies (Details 6)",
     "shortName": "Commitments and Contingencies (Details 6)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "30",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate",
      "unitRef": "Pure",
      "xsiNil": "false",
      "lang": null,
      "decimals": "INF",
      "ancestors": [
       "span",
       "span",
       "td",
       "tr",
       "table",
       "avxl:ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock",
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate",
      "unitRef": "Pure",
      "xsiNil": "false",
      "lang": null,
      "decimals": "INF",
      "ancestors": [
       "span",
       "span",
       "td",
       "tr",
       "table",
       "avxl:ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock",
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R31": {
     "role": "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative",
     "longName": "00000031 - Disclosure - Commitments and Contingencies (Details Narrative)",
     "shortName": "Commitments and Contingencies (Details Narrative)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "31",
     "firstAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "us-gaap:OperatingLeaseWeightedAverageRemainingLeaseTerm1",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "span",
       "span",
       "p",
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "us-gaap:OperatingLeaseWeightedAverageRemainingLeaseTerm1",
      "unitRef": null,
      "xsiNil": "false",
      "lang": "en-US",
      "decimals": null,
      "ancestors": [
       "span",
       "span",
       "p",
       "us-gaap:CommitmentsDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R32": {
     "role": "http://anavex.com/role/IncomeTaxesDetails",
     "longName": "00000032 - Disclosure - Income Taxes (Details)",
     "shortName": "Income Taxes (Details)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "32",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock",
       "us-gaap:IncomeTaxDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock",
       "us-gaap:IncomeTaxDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R33": {
     "role": "http://anavex.com/role/IncomeTaxesDetails1",
     "longName": "00000033 - Disclosure - Income Taxes (Details 1)",
     "shortName": "Income Taxes (Details 1)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "33",
     "firstAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "us-gaap:DeferredTaxAssetsOperatingLossCarryforwards",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock",
       "us-gaap:IncomeTaxDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "AsOf2023-09-30",
      "name": "us-gaap:DeferredTaxAssetsOperatingLossCarryforwards",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock",
       "us-gaap:IncomeTaxDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R34": {
     "role": "http://anavex.com/role/IncomeTaxesDetails2",
     "longName": "00000034 - Disclosure - Income Taxes (Details 2)",
     "shortName": "Income Taxes (Details 2)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "34",
     "firstAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock",
       "us-gaap:IncomeTaxDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "From2022-10-01to2023-09-30",
      "name": "us-gaap:IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-3",
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "us-gaap:ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock",
       "us-gaap:IncomeTaxDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    },
    "R35": {
     "role": "http://anavex.com/role/IncomeTaxesDetailsNarrative",
     "longName": "00000035 - Disclosure - Income Taxes (Details Narrative)",
     "shortName": "Income Taxes (Details Narrative)",
     "isDefault": "false",
     "groupType": "disclosure",
     "subGroupType": "details",
     "menuCat": "Details",
     "order": "35",
     "firstAnchor": {
      "contextRef": "AsOf2021-09-30",
      "name": "us-gaap:OperatingLossCarryforwards",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-5",
      "ancestors": [
       "span",
       "span",
       "p",
       "us-gaap:IncomeTaxDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     },
     "uniqueAnchor": {
      "contextRef": "AsOf2021-09-30",
      "name": "us-gaap:OperatingLossCarryforwards",
      "unitRef": "USD",
      "xsiNil": "false",
      "lang": null,
      "decimals": "-5",
      "ancestors": [
       "span",
       "span",
       "p",
       "us-gaap:IncomeTaxDisclosureTextBlock",
       "body",
       "html"
      ],
      "reportCount": 1,
      "baseRef": "e5240_10k.htm",
      "first": true,
      "unique": true
     }
    }
   },
   "tag": {
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Weighted average exercise price options vested",
        "documentation": "Weighted-average exercise price, at which grantee can acquire shares reserved for issuance, for fully vested and expected to vest exercisable or convertible options. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur."
       }
      }
     },
     "auth_ref": [
      "r199"
     ]
    },
    "avxl_OtherFinancingExpense": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "OtherFinancingExpense",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss": {
       "parentTag": "us-gaap_NonoperatingIncomeExpense",
       "weight": -1.0,
       "order": 4.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "negatedLabel": "Other financing expense",
        "label": "OtherFinancingExpense"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_StateAndLocalJurisdictionMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StateAndLocalJurisdictionMember",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "State and Local Jurisdiction [Member]",
        "documentation": "Designated tax department of a state or local government entitled to levy and collect income taxes from the entity."
       }
      }
     },
     "auth_ref": []
    },
    "avxl_StockOptionPlan2015Member": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "StockOptionPlan2015Member",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Stock Option Plan 2015 [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_Assets": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "Assets",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/BalanceSheets": {
       "parentTag": null,
       "weight": null,
       "order": null,
       "root": true
      }
     },
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "totalLabel": "Total Assets",
        "label": "Assets [Default Label]",
        "documentation": "Sum of the carrying amounts as of the balance sheet date of all assets that are recognized. Assets are probable future economic benefits obtained or controlled by an entity as a result of past transactions or events."
       }
      }
     },
     "auth_ref": [
      "r79",
      "r94",
      "r109",
      "r138",
      "r146",
      "r148",
      "r151",
      "r160",
      "r161",
      "r162",
      "r163",
      "r164",
      "r165",
      "r166",
      "r167",
      "r168",
      "r239",
      "r241",
      "r252",
      "r286",
      "r345",
      "r394",
      "r405",
      "r442",
      "r443",
      "r481"
     ]
    },
    "dei_DocumentShellCompanyReport": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "DocumentShellCompanyReport",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Document Shell Company Report",
        "documentation": "Boolean flag that is true for a Shell Company Report pursuant to section 13 or 15(d) of the Exchange Act."
       }
      }
     },
     "auth_ref": [
      "r419"
     ]
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Number of warrants outstanding",
        "documentation": "Number of fully vested and expected to vest options outstanding that can be converted into shares under option plan. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur."
       }
      }
     },
     "auth_ref": [
      "r198"
     ]
    },
    "avxl_StockOptionPlan2019Member": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "StockOptionPlan2019Member",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Stock Option Plan 2019 [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Exercise Price",
        "documentation": "Weighted-average exercise price, at which grantee can acquire shares reserved for issuance, for fully vested and expected to vest options outstanding. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur."
       }
      }
     },
     "auth_ref": [
      "r198"
     ]
    },
    "avxl_StockOptionPlan2022Member": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "StockOptionPlan2022Member",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Stock Option Plan 2022 [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_StatementOfStockholdersEquityAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StatementOfStockholdersEquityAbstract",
     "auth_ref": []
    },
    "us-gaap_StatementOfCashFlowsAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StatementOfCashFlowsAbstract",
     "lang": {
      "en-us": {
       "role": {
        "label": "Statement of Cash Flows [Abstract]"
       }
      }
     },
     "auth_ref": []
    },
    "dei_AnnualInformationForm": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "AnnualInformationForm",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Annual Information Form",
        "documentation": "Boolean flag with value true on a form if it is an annual report containing an annual information form."
       }
      }
     },
     "auth_ref": [
      "r420"
     ]
    },
    "avxl_PurchaseWarrants1Member": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "PurchaseWarrants1Member",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Purchase Warrants 1 [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "dei_DocumentPeriodStartDate": {
     "xbrltype": "dateItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "DocumentPeriodStartDate",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Document Period Start Date",
        "documentation": "The start date of the period covered in the document, in YYYY-MM-DD format."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_CommonStockSharesIssued": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CommonStockSharesIssued",
     "presentation": [
      "http://anavex.com/role/BalanceSheetsParenthetical"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Common shares, issued",
        "documentation": "Total number of common shares of an entity that have been sold or granted to shareholders (includes common shares that were issued, repurchased and remain in the treasury). These shares represent capital invested by the firm's shareholders and owners, and may be all or only a portion of the number of shares authorized. Shares issued include shares outstanding and shares held in the treasury."
       }
      }
     },
     "auth_ref": [
      "r53"
     ]
    },
    "avxl_PurchaseWarrants2Member": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "PurchaseWarrants2Member",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Purchase Warrants 2 [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_OptionPrice1Member": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "OptionPrice1Member",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Option Price 1 [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_CommonStockValue": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CommonStockValue",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/BalanceSheets": {
       "parentTag": "us-gaap_StockholdersEquity",
       "weight": 1.0,
       "order": 2.0
      }
     },
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Capital stock Authorized: 200,000,000 common stock, par value $0.001 per Issued and outstanding: 82,066,511 common shares (2022 - 77,942,815)",
        "documentation": "Aggregate par or stated value of issued nonredeemable common stock (or common stock redeemable solely at the option of the issuer). This item includes treasury stock repurchased by the entity. Note: elements for number of nonredeemable common shares, par value and other disclosure concepts are in another section within stockholders' equity."
       }
      }
     },
     "auth_ref": [
      "r53",
      "r289",
      "r394"
     ]
    },
    "us-gaap_DefinedContributionPlanDisclosuresTableTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "DefinedContributionPlanDisclosuresTableTextBlock",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesTables"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Schedule of contributions under the plan",
        "documentation": "Tabular disclosure of defined contribution pension plans or defined contribution other postretirement plans, separately for pension plans and other postretirement benefit plans."
       }
      }
     },
     "auth_ref": [
      "r32"
     ]
    },
    "avxl_OptionPrice2Member": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "OptionPrice2Member",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Option Price 2 [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_CommonStockSharesAuthorized": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CommonStockSharesAuthorized",
     "presentation": [
      "http://anavex.com/role/BalanceSheetsParenthetical"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Common shares, authorized",
        "documentation": "The maximum number of common shares permitted to be issued by an entity's charter and bylaws."
       }
      }
     },
     "auth_ref": [
      "r53",
      "r332"
     ]
    },
    "dei_DocumentTransitionReport": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "DocumentTransitionReport",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Document Transition Report",
        "documentation": "Boolean flag that is true only for a form used as a transition report."
       }
      }
     },
     "auth_ref": [
      "r421"
     ]
    },
    "us-gaap_CommonStockSharesOutstanding": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CommonStockSharesOutstanding",
     "presentation": [
      "http://anavex.com/role/BalanceSheetsParenthetical"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Common shares, outstanding",
        "documentation": "Number of shares of common stock outstanding. Common stock represent the ownership interest in a corporation."
       }
      }
     },
     "auth_ref": [
      "r9",
      "r53",
      "r332",
      "r351",
      "r485",
      "r486"
     ]
    },
    "us-gaap_PaymentsOfStockIssuanceCosts": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "PaymentsOfStockIssuanceCosts",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/StatementsOfCashFlows": {
       "parentTag": "us-gaap_NetCashProvidedByUsedInFinancingActivities",
       "weight": -1.0,
       "order": 2.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "negatedLabel": "Share issue costs",
        "label": "Payments of Stock Issuance Costs",
        "documentation": "The cash outflow for cost incurred directly with the issuance of an equity security."
       }
      }
     },
     "auth_ref": [
      "r20"
     ]
    },
    "avxl_OptionPrice3Member": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "OptionPrice3Member",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Option Price 3 [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_RetainedEarningsAccumulatedDeficit": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "RetainedEarningsAccumulatedDeficit",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/BalanceSheets": {
       "parentTag": "us-gaap_StockholdersEquity",
       "weight": 1.0,
       "order": 4.0
      }
     },
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Accumulated deficit",
        "documentation": "Amount of accumulated undistributed earnings (deficit)."
       }
      }
     },
     "auth_ref": [
      "r55",
      "r72",
      "r290",
      "r298",
      "r299",
      "r308",
      "r333",
      "r394"
     ]
    },
    "us-gaap_StockOptionMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StockOptionMember",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3",
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Equity Option [Member]",
        "documentation": "Contracts conveying rights, but not obligations, to buy or sell a specific quantity of stock at a specified price during a specified period (an American option) or at a specified date (a European option)."
       }
      }
     },
     "auth_ref": [
      "r397"
     ]
    },
    "avxl_OptionPrice4Member": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "OptionPrice4Member",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Option Price 4 [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_OptionPrice5Member": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "OptionPrice5Member",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Option Price 5 [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_ResearchAndDevelopmentIncentiveIncome": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "ResearchAndDevelopmentIncentiveIncome",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss": {
       "parentTag": "us-gaap_NonoperatingIncomeExpense",
       "weight": 1.0,
       "order": 2.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Research and development incentive income"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_RelatedPartyTransactionsByRelatedPartyAxis": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "RelatedPartyTransactionsByRelatedPartyAxis",
     "presentation": [
      "http://anavex.com/role/OtherIncomeDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Related Party, Type [Axis]",
        "documentation": "Information by type of related party. Related parties include, but not limited to, affiliates; other entities for which investments are accounted for by the equity method by the entity; trusts for benefit of employees; and principal owners, management, and members of immediate families. It also may include other parties with which the entity may control or can significantly influence the management or operating policies of the other to an extent that one of the transacting parties might be prevented from fully pursuing its own separate interests."
       }
      }
     },
     "auth_ref": [
      "r175",
      "r267",
      "r268",
      "r272",
      "r273",
      "r274",
      "r275",
      "r276",
      "r277",
      "r278",
      "r279",
      "r280",
      "r281",
      "r282",
      "r283",
      "r325",
      "r326",
      "r327",
      "r328",
      "r329",
      "r350",
      "r352",
      "r376",
      "r480"
     ]
    },
    "avxl_NonOperatingIncomeFromGrants": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "NonOperatingIncomeFromGrants",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss": {
       "parentTag": "us-gaap_NonoperatingIncomeExpense",
       "weight": 1.0,
       "order": 1.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Grant income"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_FederalMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "FederalMember",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Federal [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_DerivativeContractTypeDomain": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "DerivativeContractTypeDomain",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3",
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Financial instrument or contract with one or more underlyings, notional amount or payment provision or both, and the contract can be net settled by means outside the contract or delivery of an asset."
       }
      }
     },
     "auth_ref": [
      "r322",
      "r323",
      "r337",
      "r338",
      "r339",
      "r341",
      "r342",
      "r343",
      "r344",
      "r346",
      "r347",
      "r348",
      "r349",
      "r360",
      "r361",
      "r362",
      "r363",
      "r366",
      "r367",
      "r368",
      "r369",
      "r377",
      "r378",
      "r379",
      "r380",
      "r395",
      "r397"
     ]
    },
    "us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract",
     "lang": {
      "en-us": {
       "role": {
        "label": "Organization, Consolidation and Presentation of Financial Statements [Abstract]"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract",
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Cash Flows used in Operating Activities"
       }
      }
     },
     "auth_ref": []
    },
    "dei_DocumentQuarterlyReport": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "DocumentQuarterlyReport",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Document Quarterly Report",
        "documentation": "Boolean flag that is true only for a form used as an quarterly report."
       }
      }
     },
     "auth_ref": [
      "r418"
     ]
    },
    "dei_EntityRegistrantName": {
     "xbrltype": "normalizedStringItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityRegistrantName",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Registrant Name",
        "documentation": "The exact name of the entity filing the report as specified in its charter, which is required by forms filed with the SEC."
       }
      }
     },
     "auth_ref": [
      "r408"
     ]
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate": {
     "xbrltype": "percentItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails6"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Risk-free interest rate",
        "documentation": "The risk-free interest rate assumption that is used in valuing an option on its own shares."
       }
      }
     },
     "auth_ref": [
      "r203"
     ]
    },
    "us-gaap_GeneralAndAdministrativeExpense": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "GeneralAndAdministrativeExpense",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss": {
       "parentTag": "us-gaap_OperatingExpenses",
       "weight": 1.0,
       "order": 1.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "General and administrative",
        "documentation": "The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line."
       }
      }
     },
     "auth_ref": [
      "r64",
      "r356"
     ]
    },
    "us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/StatementsOfCashFlows": {
       "parentTag": null,
       "weight": null,
       "order": null,
       "root": true
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "totalLabel": "Increase in cash and cash equivalents during the period",
        "label": "Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Excluding Exchange Rate Effect",
        "documentation": "Amount of increase (decrease) in cash and cash equivalents, and cash and cash equivalents restricted to withdrawal or usage; excluding effect from exchange rate change. Cash includes, but is not limited to, currency on hand, demand deposits with banks or financial institutions, and other accounts with general characteristics of demand deposits. Cash equivalents include, but are not limited to, short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates."
       }
      }
     },
     "auth_ref": [
      "r1",
      "r66"
     ]
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate": {
     "xbrltype": "percentItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails6"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Annualized volatility",
        "documentation": "The estimated measure of the percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period."
       }
      }
     },
     "auth_ref": [
      "r201"
     ]
    },
    "dei_Extension": {
     "xbrltype": "normalizedStringItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "Extension",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Extension",
        "documentation": "Extension number for local phone number."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SaleOfStockNumberOfSharesIssuedInTransaction",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Number of common stock sold",
        "documentation": "The number of shares issued or sold by the subsidiary or equity method investee per stock transaction."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_LossContingenciesTable": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "LossContingenciesTable",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails5"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Loss Contingencies [Table]",
        "documentation": "Discloses the specific components (such as the nature, name, and date) of the loss contingency and gives an estimate of the possible loss or range of loss, or states that a reasonable estimate cannot be made. Excludes environmental contingencies, warranties and unconditional purchase obligations."
       }
      }
     },
     "auth_ref": [
      "r156",
      "r157",
      "r158",
      "r159",
      "r440",
      "r441"
     ]
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate": {
     "xbrltype": "percentItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails6"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Dividend rate",
        "documentation": "The estimated dividend rate (a percentage of the share price) to be paid (expected dividends) to holders of the underlying shares over the option's term."
       }
      }
     },
     "auth_ref": [
      "r202"
     ]
    },
    "us-gaap_CashAndCashEquivalentsPolicyTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CashAndCashEquivalentsPolicyTextBlock",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Cash and equivalents",
        "documentation": "Disclosure of accounting policy for cash and cash equivalents, including the policy for determining which items are treated as cash equivalents. Other information that may be disclosed includes (1) the nature of any restrictions on the entity's use of its cash and cash equivalents, (2) whether the entity's cash and cash equivalents are insured or expose the entity to credit risk, (3) the classification of any negative balance accounts (overdrafts), and (4) the carrying basis of cash equivalents (for example, at cost) and whether the carrying amount of cash equivalents approximates fair value."
       }
      }
     },
     "auth_ref": [
      "r22"
     ]
    },
    "us-gaap_LossContingenciesLineItems": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "LossContingenciesLineItems",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails5"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Loss Contingencies [Line Items]",
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table."
       }
      }
     },
     "auth_ref": [
      "r156",
      "r157",
      "r158",
      "r159",
      "r440",
      "r441"
     ]
    },
    "us-gaap_CashAndCashEquivalentsAtCarryingValue": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CashAndCashEquivalentsAtCarryingValue",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/BalanceSheets": {
       "parentTag": "us-gaap_Assets",
       "weight": 1.0,
       "order": 1.0
      }
     },
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Cash and cash equivalents",
        "documentation": "Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation."
       }
      }
     },
     "auth_ref": [
      "r21",
      "r93",
      "r386"
     ]
    },
    "dei_EntityCentralIndexKey": {
     "xbrltype": "centralIndexKeyItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityCentralIndexKey",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Central Index Key",
        "documentation": "A unique 10-digit SEC-issued value to identify entities that have filed disclosures with the SEC. It is commonly abbreviated as CIK."
       }
      }
     },
     "auth_ref": [
      "r408"
     ]
    },
    "us-gaap_SaleOfStockConsiderationReceivedOnTransaction": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SaleOfStockConsiderationReceivedOnTransaction",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Gross proceeds from sale of stock",
        "documentation": "Cash received on stock transaction after deduction of issuance costs."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Award under share-based payment arrangement."
       }
      }
     },
     "auth_ref": [
      "r179",
      "r180",
      "r181",
      "r182",
      "r183",
      "r184",
      "r185",
      "r186",
      "r187",
      "r188",
      "r189",
      "r190",
      "r191",
      "r192",
      "r193",
      "r194",
      "r195",
      "r196",
      "r197",
      "r198",
      "r199",
      "r200",
      "r201",
      "r202",
      "r203",
      "r204"
     ]
    },
    "dei_EntityFileNumber": {
     "xbrltype": "fileNumberItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityFileNumber",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity File Number",
        "documentation": "Commission file number. The field allows up to 17 characters. The prefix may contain 1-3 digits, the sequence number may contain 1-8 digits, the optional suffix may contain 1-4 characters, and the fields are separated with a hyphen."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails2",
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]",
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table."
       }
      }
     },
     "auth_ref": [
      "r176",
      "r178",
      "r179",
      "r180",
      "r181",
      "r182",
      "r183",
      "r184",
      "r185",
      "r186",
      "r187",
      "r188",
      "r189",
      "r190",
      "r191",
      "r192",
      "r193",
      "r194",
      "r195",
      "r196",
      "r197",
      "r198",
      "r199",
      "r200",
      "r201",
      "r202",
      "r203",
      "r204"
     ]
    },
    "us-gaap_DeferredTaxAssetsGross": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "DeferredTaxAssetsGross",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Gross deferred tax asset",
        "documentation": "Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards."
       }
      }
     },
     "auth_ref": [
      "r223"
     ]
    },
    "us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails2",
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]",
        "documentation": "Disclosure of information about share-based payment arrangement."
       }
      }
     },
     "auth_ref": [
      "r176",
      "r178",
      "r179",
      "r180",
      "r181",
      "r182",
      "r183",
      "r184",
      "r185",
      "r186",
      "r187",
      "r188",
      "r189",
      "r190",
      "r191",
      "r192",
      "r193",
      "r194",
      "r195",
      "r196",
      "r197",
      "r198",
      "r199",
      "r200",
      "r201",
      "r202",
      "r203",
      "r204"
     ]
    },
    "us-gaap_SaleOfStockPricePerShare": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SaleOfStockPricePerShare",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Sale of stock, per share",
        "documentation": "Per share amount received by subsidiary or equity investee for each share of common stock issued or sold in the stock transaction."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "periodStartLabel": "Cash and cash equivalents, beginning of period",
        "periodEndLabel": "Cash and cash equivalents, end of period",
        "label": "Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents",
        "documentation": "Amount of cash and cash equivalents, and cash and cash equivalents restricted to withdrawal or usage. Excludes amount for disposal group and discontinued operations. Cash includes, but is not limited to, currency on hand, demand deposits with banks or financial institutions, and other accounts with general characteristics of demand deposits. Cash equivalents include, but are not limited to, short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates."
       }
      }
     },
     "auth_ref": [
      "r21",
      "r66",
      "r107"
     ]
    },
    "us-gaap_RelatedPartyDomain": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "RelatedPartyDomain",
     "presentation": [
      "http://anavex.com/role/OtherIncomeDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Related parties include affiliates; other entities for which investments are accounted for by the equity method by the entity; trusts for benefit of employees; and principal owners, management, and members of immediate families. It also may include other parties with which the entity may control or can significantly influence the management or operating policies of the other to an extent that one of the transacting parties might be prevented from fully pursuing its own separate interests."
       }
      }
     },
     "auth_ref": [
      "r175",
      "r267",
      "r268",
      "r325",
      "r326",
      "r327",
      "r328",
      "r329",
      "r350",
      "r352",
      "r376"
     ]
    },
    "dei_EntityPrimarySicNumber": {
     "xbrltype": "sicNumberItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityPrimarySicNumber",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Primary SIC Number",
        "documentation": "Primary Standard Industrial Classification (SIC) Number for the Entity."
       }
      }
     },
     "auth_ref": [
      "r420"
     ]
    },
    "us-gaap_CommonStockParOrStatedValuePerShare": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CommonStockParOrStatedValuePerShare",
     "presentation": [
      "http://anavex.com/role/BalanceSheetsParenthetical"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Common shares, par value",
        "documentation": "Face amount or stated value per share of common stock."
       }
      }
     },
     "auth_ref": [
      "r53"
     ]
    },
    "us-gaap_DefinedBenefitPlanDisclosureLineItems": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "DefinedBenefitPlanDisclosureLineItems",
     "presentation": [
      "http://anavex.com/role/OtherIncomeDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Defined Benefit Plan Disclosure [Line Items]",
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_SaleOfStockConsiderationReceivedPerTransaction": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SaleOfStockConsiderationReceivedPerTransaction",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Number of common stock sold, value",
        "documentation": "Amount of consideration received by subsidiary or equity investee in exchange for shares of stock issued or sold. Includes amount of cash received, fair value of noncash assets received, and fair value of liabilities assumed by the investor."
       }
      }
     },
     "auth_ref": []
    },
    "dei_EntityTaxIdentificationNumber": {
     "xbrltype": "employerIdItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityTaxIdentificationNumber",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Tax Identification Number",
        "documentation": "The Tax Identification Number (TIN), also known as an Employer Identification Number (EIN), is a unique 9-digit value assigned by the IRS."
       }
      }
     },
     "auth_ref": [
      "r408"
     ]
    },
    "us-gaap_StatementClassOfStockAxis": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StatementClassOfStockAxis",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Class of Stock [Axis]",
        "documentation": "Information by the different classes of stock of the entity."
       }
      }
     },
     "auth_ref": [
      "r90",
      "r95",
      "r96",
      "r97",
      "r109",
      "r127",
      "r128",
      "r130",
      "r132",
      "r136",
      "r137",
      "r151",
      "r160",
      "r162",
      "r163",
      "r164",
      "r167",
      "r168",
      "r169",
      "r170",
      "r171",
      "r172",
      "r173",
      "r252",
      "r304",
      "r305",
      "r306",
      "r307",
      "r310",
      "r311",
      "r312",
      "r313",
      "r314",
      "r315",
      "r316",
      "r317",
      "r318",
      "r319",
      "r320",
      "r321",
      "r332",
      "r354",
      "r373",
      "r381",
      "r382",
      "r383",
      "r384",
      "r385",
      "r427",
      "r432",
      "r438"
     ]
    },
    "us-gaap_CommonStockMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CommonStockMember",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative",
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Common Stock [Member]",
        "documentation": "Stock that is subordinate to all other stock of the issuer."
       }
      }
     },
     "auth_ref": [
      "r395",
      "r396",
      "r397",
      "r399",
      "r400",
      "r401",
      "r402",
      "r435",
      "r436",
      "r474",
      "r484",
      "r485"
     ]
    },
    "us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ScheduleOfDefinedBenefitPlansDisclosuresTable",
     "presentation": [
      "http://anavex.com/role/OtherIncomeDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Schedule of Defined Benefit Plans Disclosures [Table]",
        "documentation": "Disclosures about an individual defined benefit pension plan or an other postretirement defined benefit plan. It may be appropriate to group certain similar plans. Also includes schedule for fair value of plan assets by major categories of plan assets by the level within the fair value hierarchy in which the fair value measurements in their entirety fall, segregating fair value measurements using quoted prices in active markets for identical assets or liabilities (Level 1), Significant other observable inputs (Level 2), and significant unobservable inputs (Level 3)."
       }
      }
     },
     "auth_ref": [
      "r7",
      "r28",
      "r29",
      "r30",
      "r31"
     ]
    },
    "us-gaap_StockholdersEquity": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StockholdersEquity",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/BalanceSheets": {
       "parentTag": "us-gaap_LiabilitiesAndStockholdersEquity",
       "weight": 1.0,
       "order": 2.0
      }
     },
     "presentation": [
      "http://anavex.com/role/BalanceSheets",
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "totalLabel": "Total Stockholders' Equity",
        "periodStartLabel": "Beginning balance, value",
        "periodEndLabel": "Ending balance, value",
        "label": "Equity, Attributable to Parent",
        "documentation": "Amount of equity (deficit) attributable to parent. Excludes temporary equity and equity attributable to noncontrolling interest."
       }
      }
     },
     "auth_ref": [
      "r53",
      "r56",
      "r57",
      "r70",
      "r334",
      "r351",
      "r374",
      "r375",
      "r394",
      "r405",
      "r433",
      "r439",
      "r476",
      "r485"
     ]
    },
    "us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "DeferredTaxAssetsInProcessResearchAndDevelopment",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails1"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Research and development tax credit carryforwards",
        "documentation": "Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from in-process research and development costs expensed in connection with a business combination."
       }
      }
     },
     "auth_ref": [
      "r42",
      "r473"
     ]
    },
    "us-gaap_GeneralAndAdministrativeExpenseMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "GeneralAndAdministrativeExpenseMember",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails5"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "General and Administrative Expense [Member]",
        "documentation": "Primary financial statement caption encompassing general and administrative expense."
       }
      }
     },
     "auth_ref": [
      "r63"
     ]
    },
    "dei_EntityIncorporationStateCountryCode": {
     "xbrltype": "edgarStateCountryItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityIncorporationStateCountryCode",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Incorporation, State or Country Code",
        "documentation": "Two-character EDGAR code representing the state or country of incorporation."
       }
      }
     },
     "auth_ref": []
    },
    "dei_CurrentFiscalYearEndDate": {
     "xbrltype": "gMonthDayItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "CurrentFiscalYearEndDate",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Current Fiscal Year End Date",
        "documentation": "End date of current fiscal year in the format --MM-DD."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Number of options, Granted",
        "documentation": "Gross number of share options (or share units) granted during the period."
       }
      }
     },
     "auth_ref": [
      "r186"
     ]
    },
    "us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "WeightedAverageNumberOfSharesOutstandingAbstract",
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Weighted average number of shares outstanding Basic and diluted"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_DeferredTaxAssetsOperatingLossCarryforwards": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "DeferredTaxAssetsOperatingLossCarryforwards",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails1"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Net operating loss carryforwards",
        "documentation": "Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards."
       }
      }
     },
     "auth_ref": [
      "r42",
      "r473"
     ]
    },
    "us-gaap_ResearchAndDevelopmentExpenseMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ResearchAndDevelopmentExpenseMember",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails5"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Research and Development Expense [Member]",
        "documentation": "Primary financial statement caption in which the reported facts about research and development expense have been included."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_DeferredTaxAssetsNet": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "DeferredTaxAssetsNet",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails1"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Net deferred tax assets",
        "documentation": "Amount after allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards."
       }
      }
     },
     "auth_ref": [
      "r472"
     ]
    },
    "us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ValuationAllowanceDeferredTaxAssetChangeInAmount",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Decrease in valuation allowance",
        "documentation": "Amount of increase (decrease) in the valuation allowance for a specified deferred tax asset."
       }
      }
     },
     "auth_ref": [
      "r222"
     ]
    },
    "us-gaap_IncreaseDecreaseInIncomeTaxesReceivable": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncreaseDecreaseInIncomeTaxesReceivable",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/StatementsOfCashFlows": {
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": -1.0,
       "order": 4.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "negatedLabel": "Incentive and tax receivables",
        "label": "Increase (Decrease) in Income Taxes Receivable",
        "documentation": "The increase (decrease) during the reporting period in income taxes receivable, which represents the amount due from tax authorities for refunds of overpayments or recoveries of income taxes paid."
       }
      }
     },
     "auth_ref": [
      "r4"
     ]
    },
    "dei_EntityWellKnownSeasonedIssuer": {
     "xbrltype": "yesNoItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityWellKnownSeasonedIssuer",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Well-known Seasoned Issuer",
        "documentation": "Indicate 'Yes' or 'No' if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Is used on Form Type: 10-K, 10-Q, 8-K, 20-F, 6-K, 10-K/A, 10-Q/A, 20-F/A, 6-K/A, N-CSR, N-Q, N-1A."
       }
      }
     },
     "auth_ref": [
      "r424"
     ]
    },
    "us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesTables"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Schedule of general and administrative expenses and research and development expenses",
        "documentation": "Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement."
       }
      }
     },
     "auth_ref": [
      "r37"
     ]
    },
    "dei_EntityVoluntaryFilers": {
     "xbrltype": "yesNoItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityVoluntaryFilers",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Voluntary Filers",
        "documentation": "Indicate 'Yes' or 'No' if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_OtherAccruedLiabilitiesCurrent": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "OtherAccruedLiabilitiesCurrent",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/AccruedLiabilitiesDetails": {
       "parentTag": "us-gaap_AccruedLiabilitiesCurrent",
       "weight": 1.0,
       "order": 5.0
      }
     },
     "presentation": [
      "http://anavex.com/role/AccruedLiabilitiesDetails"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "All other accrued liabilities",
        "documentation": "Amount of expenses incurred but not yet paid classified as other, due within one year or the normal operating cycle, if longer."
       }
      }
     },
     "auth_ref": [
      "r16"
     ]
    },
    "dei_EntityCurrentReportingStatus": {
     "xbrltype": "yesNoItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityCurrentReportingStatus",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Current Reporting Status",
        "documentation": "Indicate 'Yes' or 'No' whether registrants (1) have filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that registrants were required to file such reports), and (2) have been subject to such filing requirements for the past 90 days. This information should be based on the registrant's current or most recent filing containing the related disclosure."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_CurrentIncomeTaxExpenseBenefit": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CurrentIncomeTaxExpenseBenefit",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss": {
       "parentTag": "us-gaap_NetIncomeLoss",
       "weight": -1.0,
       "order": 2.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "negatedLabel": "Income tax expense, current",
        "label": "Current Income Tax Expense (Benefit)",
        "documentation": "Amount of current income tax expense (benefit) pertaining to taxable income (loss) from continuing operations."
       }
      }
     },
     "auth_ref": [
      "r77",
      "r228",
      "r233",
      "r434"
     ]
    },
    "us-gaap_FairValueOfFinancialInstrumentsPolicy": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "FairValueOfFinancialInstrumentsPolicy",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Financial Instruments",
        "documentation": "Disclosure of accounting policy for determining the fair value of financial instruments."
       }
      }
     },
     "auth_ref": [
      "r6",
      "r13"
     ]
    },
    "us-gaap_ResearchAndDevelopmentExpensePolicy": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ResearchAndDevelopmentExpensePolicy",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Research and Development Expenses",
        "documentation": "Disclosure of accounting policy for costs it has incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process."
       }
      }
     },
     "auth_ref": [
      "r211"
     ]
    },
    "us-gaap_EffectiveIncomeTaxRateReconciliationGiltiAmount": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "EffectiveIncomeTaxRateReconciliationGiltiAmount",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Permanent differences relating to GILTI inclusion",
        "documentation": "Amount of reported income tax expense from difference to expected income tax expense (benefit) computed by applying domestic federal statutory income tax rate to pretax income (loss) from continuing operations, attributable to global intangible low-taxed income (GILTI)."
       }
      }
     },
     "auth_ref": [
      "r471"
     ]
    },
    "us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/OtherIncomeDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "verboseLabel": "Research and development incentive income",
        "label": "Research and Development Arrangement, Contract to Perform for Others, Compensation Earned",
        "documentation": "The amount of compensation earned (contract income) under a research and development arrangement accounted for as a contract to perform research and development for others."
       }
      }
     },
     "auth_ref": [
      "r213"
     ]
    },
    "us-gaap_LiabilitiesCurrentAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "LiabilitiesCurrentAbstract",
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Current Liabilities"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_AllocatedShareBasedCompensationExpense": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "AllocatedShareBasedCompensationExpense",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "verboseLabel": "Share based compensation",
        "label": "Share-Based Payment Arrangement, Expense",
        "documentation": "Amount of expense for award under share-based payment arrangement. Excludes amount capitalized."
       }
      }
     },
     "auth_ref": [
      "r205",
      "r210"
     ]
    },
    "us-gaap_IncreaseDecreaseInOperatingCapitalAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncreaseDecreaseInOperatingCapitalAbstract",
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Changes in working capital balances related to operations:"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "United States",
        "documentation": "The portion of earnings or loss from continuing operations before income taxes that is attributable to domestic operations."
       }
      }
     },
     "auth_ref": [
      "r110",
      "r234"
     ]
    },
    "us-gaap_IncreaseDecreaseInAccountsPayable": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncreaseDecreaseInAccountsPayable",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/StatementsOfCashFlows": {
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": 1.0,
       "order": 6.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "verboseLabel": "Accounts payable",
        "label": "Increase (Decrease) in Accounts Payable",
        "documentation": "The increase (decrease) during the reporting period in the aggregate amount of liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received that are used in an entity's business."
       }
      }
     },
     "auth_ref": [
      "r4"
     ]
    },
    "us-gaap_TaxesExcludingIncomeAndExciseTaxes": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "TaxesExcludingIncomeAndExciseTaxes",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "State minimum and excise taxes",
        "documentation": "All taxes not related to income of the entity or excise or sales taxes levied on the revenue of the entity that are not reported elsewhere. These taxes could include production, real estate, personal property, and pump tax."
       }
      }
     },
     "auth_ref": [
      "r430"
     ]
    },
    "us-gaap_IncreaseDecreaseInAccruedLiabilities": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncreaseDecreaseInAccruedLiabilities",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/StatementsOfCashFlows": {
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": 1.0,
       "order": 7.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Accrued liabilities",
        "documentation": "The increase (decrease) during the reporting period in the aggregate amount of expenses incurred but not yet paid."
       }
      }
     },
     "auth_ref": [
      "r4"
     ]
    },
    "us-gaap_OffsettingAssetsLineItems": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "OffsettingAssetsLineItems",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3",
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Offsetting Assets [Line Items]",
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_CommonStockCapitalSharesReservedForFutureIssuance": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CommonStockCapitalSharesReservedForFutureIssuance",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Maximum number of common shares reserved for future issuance",
        "documentation": "Aggregate number of common shares reserved for future issuance."
       }
      }
     },
     "auth_ref": [
      "r18"
     ]
    },
    "us-gaap_ShareBasedCompensation": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensation",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/StatementsOfCashFlows": {
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": 1.0,
       "order": 3.0
      }
     },
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails5",
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Stock-based compensation",
        "verboseLabel": "Total share based compensation",
        "documentation": "Amount of noncash expense for share-based payment arrangement."
       }
      }
     },
     "auth_ref": [
      "r4"
     ]
    },
    "us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Foreign",
        "documentation": "The portion of earnings or loss from continuing operations before income taxes that is attributable to foreign operations, which is defined as Income or Loss generated from operations located outside the entity's country of domicile."
       }
      }
     },
     "auth_ref": [
      "r110",
      "r234"
     ]
    },
    "us-gaap_CashFDICInsuredAmount": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CashFDICInsuredAmount",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Federal deposit insurance corporation",
        "documentation": "The amount of cash deposited in financial institutions as of the balance sheet date that is insured by the Federal Deposit Insurance Corporation."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ResearchAndDevelopmentExpense": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ResearchAndDevelopmentExpense",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss": {
       "parentTag": "us-gaap_OperatingExpenses",
       "weight": 1.0,
       "order": 2.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Research and development",
        "documentation": "The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use."
       }
      }
     },
     "auth_ref": [
      "r50",
      "r212",
      "r483"
     ]
    },
    "us-gaap_EarningsPerShareDiluted": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "EarningsPerShareDiluted",
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLossParenthetical"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Net Loss per share, Diluted",
        "documentation": "The amount of net income (loss) for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period."
       }
      }
     },
     "auth_ref": [
      "r105",
      "r117",
      "r118",
      "r119",
      "r120",
      "r121",
      "r127",
      "r130",
      "r131",
      "r132",
      "r134",
      "r250",
      "r251",
      "r284",
      "r294",
      "r389"
     ]
    },
    "us-gaap_NonoperatingIncomeExpenseAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "NonoperatingIncomeExpenseAbstract",
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Other income (expenses)"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_CommitmentsAndContingencies": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CommitmentsAndContingencies",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Commitments and Contingencies - Note 6",
        "documentation": "Represents the caption on the face of the balance sheet to indicate that the entity has entered into (1) purchase or supply arrangements that will require expending a portion of its resources to meet the terms thereof, and (2) is exposed to potential losses or, less frequently, gains, arising from (a) possible claims against a company's resources due to future performance under contract terms, and (b) possible losses or likely gains from uncertainties that will ultimately be resolved when one or more future events that are deemed likely to occur do occur or fail to occur."
       }
      }
     },
     "auth_ref": [
      "r17",
      "r49",
      "r287",
      "r331"
     ]
    },
    "us-gaap_ConsolidationPolicyTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ConsolidationPolicyTextBlock",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Principles of Consolidation",
        "documentation": "Disclosure of accounting policy regarding (1) the principles it follows in consolidating or combining the separate financial statements, including the principles followed in determining the inclusion or exclusion of subsidiaries or other entities in the consolidated or combined financial statements and (2) its treatment of interests (for example, common stock, a partnership interest or other means of exerting influence) in other entities, for example consolidation or use of the equity or cost methods of accounting. The accounting policy may also address the accounting treatment for intercompany accounts and transactions, noncontrolling interest, and the income statement treatment in consolidation for issuances of stock by a subsidiary."
       }
      }
     },
     "auth_ref": [
      "r43",
      "r388"
     ]
    },
    "us-gaap_NonoperatingIncomeExpense": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "NonoperatingIncomeExpense",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss": {
       "parentTag": "us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest",
       "weight": 1.0,
       "order": 2.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "totalLabel": "Total other income, net",
        "label": "Nonoperating Income (Expense)",
        "documentation": "The aggregate amount of income or expense from ancillary business-related activities (that is to say, excluding major activities considered part of the normal operations of the business)."
       }
      }
     },
     "auth_ref": [
      "r65"
     ]
    },
    "us-gaap_InterestIncomeExpenseNet": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "InterestIncomeExpenseNet",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss": {
       "parentTag": "us-gaap_NonoperatingIncomeExpense",
       "weight": 1.0,
       "order": 3.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Interest income, net",
        "documentation": "The net amount of operating interest income (expense)."
       }
      }
     },
     "auth_ref": [
      "r83"
     ]
    },
    "us-gaap_StockIssuedDuringPeriodValueNewIssues": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StockIssuedDuringPeriodValueNewIssues",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Number of shares issued, value",
        "documentation": "Equity impact of the value of new stock issued during the period. Includes shares issued in an initial public offering or a secondary public offering."
       }
      }
     },
     "auth_ref": [
      "r9",
      "r52",
      "r53",
      "r72",
      "r310",
      "r373",
      "r382",
      "r404"
     ]
    },
    "us-gaap_NetIncomeLoss": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "NetIncomeLoss",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/StatementsOfCashFlows": {
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": 1.0,
       "order": 1.0
      },
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss": {
       "parentTag": null,
       "weight": null,
       "order": null,
       "root": true
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows",
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity",
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Net loss and comprehensive loss",
        "verboseLabel": "Net loss",
        "documentation": "The portion of profit or loss for the period, net of income taxes, which is attributable to the parent."
       }
      }
     },
     "auth_ref": [
      "r62",
      "r68",
      "r82",
      "r92",
      "r99",
      "r100",
      "r104",
      "r109",
      "r115",
      "r117",
      "r118",
      "r119",
      "r120",
      "r123",
      "r124",
      "r129",
      "r138",
      "r145",
      "r147",
      "r149",
      "r151",
      "r160",
      "r161",
      "r162",
      "r163",
      "r164",
      "r165",
      "r166",
      "r167",
      "r168",
      "r251",
      "r252",
      "r293",
      "r353",
      "r371",
      "r372",
      "r391",
      "r403",
      "r442"
     ]
    },
    "dei_DocumentFiscalPeriodFocus": {
     "xbrltype": "fiscalPeriodItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "DocumentFiscalPeriodFocus",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Document Fiscal Period Focus",
        "documentation": "Fiscal period values are FY, Q1, Q2, and Q3.  1st, 2nd and 3rd quarter 10-Q or 10-QT statements have value Q1, Q2, and Q3 respectively, with 10-K, 10-KT or other fiscal year statements having FY."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_StockIssuedDuringPeriodSharesNewIssues": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StockIssuedDuringPeriodSharesNewIssues",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Number of shares issued, shares",
        "documentation": "Number of new stock issued during the period."
       }
      }
     },
     "auth_ref": [
      "r9",
      "r52",
      "r53",
      "r72",
      "r304",
      "r373",
      "r382"
     ]
    },
    "us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "NewAccountingPronouncementsPolicyPolicyTextBlock",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Recently Adopted Accounting Pronouncements",
        "documentation": "Disclosure of accounting policy pertaining to new accounting pronouncements that may impact the entity's financial reporting. Includes, but is not limited to, quantification of the expected or actual impact."
       }
      }
     },
     "auth_ref": []
    },
    "dei_DocumentAnnualReport": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "DocumentAnnualReport",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Document Annual Report",
        "documentation": "Boolean flag that is true only for a form used as an annual report."
       }
      }
     },
     "auth_ref": [
      "r417",
      "r419",
      "r420"
     ]
    },
    "us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2": {
     "xbrltype": "durationItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Options exercisable",
        "documentation": "Weighted average remaining contractual term of exercisable stock options, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days."
       }
      }
     },
     "auth_ref": [
      "r74"
     ]
    },
    "avxl_OperatingLossCarryForwardsExpirationYear": {
     "xbrltype": "stringItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "OperatingLossCarryForwardsExpirationYear",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Operating loss carry forwards expiration year"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_PreferredStockValue": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "PreferredStockValue",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/BalanceSheets": {
       "parentTag": "us-gaap_StockholdersEquity",
       "weight": 1.0,
       "order": 1.0
      }
     },
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Capital stock Authorized:10,000,000 preferred stock, par value $0.001 per share",
        "documentation": "Aggregate par or stated value of issued nonredeemable preferred stock (or preferred stock redeemable solely at the option of the issuer). This item includes treasury stock repurchased by the entity. Note: elements for number of nonredeemable preferred shares, par value and other disclosure concepts are in another section within stockholders' equity."
       }
      }
     },
     "auth_ref": [
      "r52",
      "r288",
      "r394"
     ]
    },
    "dei_DocumentAccountingStandard": {
     "xbrltype": "accountingStandardItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "DocumentAccountingStandard",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Document Accounting Standard",
        "documentation": "The basis of accounting the registrant has used to prepare the financial statements included in this filing This can either be 'U.S. GAAP', 'International Financial Reporting Standards', or 'Other'."
       }
      }
     },
     "auth_ref": [
      "r419"
     ]
    },
    "dei_DocumentType": {
     "xbrltype": "submissionTypeItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "DocumentType",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Document Type",
        "documentation": "The type of document being provided (such as 10-K, 10-Q, 485BPOS, etc). The document type is limited to the same value as the supporting SEC submission type, or the word 'Other'."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ProceedsFromIssuanceOfCommonStock": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ProceedsFromIssuanceOfCommonStock",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/StatementsOfCashFlows": {
       "parentTag": "us-gaap_NetCashProvidedByUsedInFinancingActivities",
       "weight": 1.0,
       "order": 1.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Issuance of common shares",
        "documentation": "The cash inflow from the additional capital contribution to the entity."
       }
      }
     },
     "auth_ref": [
      "r2"
     ]
    },
    "us-gaap_EarningsPerShareBasic": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "EarningsPerShareBasic",
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLossParenthetical"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Net Loss per share, Basic",
        "documentation": "The amount of net income (loss) for the period per each share of common stock or unit outstanding during the reporting period."
       }
      }
     },
     "auth_ref": [
      "r105",
      "r117",
      "r118",
      "r119",
      "r120",
      "r121",
      "r125",
      "r127",
      "r130",
      "r131",
      "r132",
      "r134",
      "r250",
      "r251",
      "r284",
      "r294",
      "r389"
     ]
    },
    "us-gaap_ProceedsFromIssuanceOrSaleOfEquity": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ProceedsFromIssuanceOrSaleOfEquity",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Proceeds from issuance or sale of equity",
        "documentation": "The cash inflow from the issuance of common stock, preferred stock, treasury stock, stock options, and other types of equity."
       }
      }
     },
     "auth_ref": [
      "r2",
      "r304"
     ]
    },
    "dei_DocumentPeriodEndDate": {
     "xbrltype": "dateItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "DocumentPeriodEndDate",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Document Period End Date",
        "documentation": "For the EDGAR submission types of Form 8-K: the date of the report, the date of the earliest event reported; for the EDGAR submission types of Form N-1A: the filing date; for all other submission types: the end of the reporting or transition period.  The format of the date is YYYY-MM-DD."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ProceedsFromIssuanceInitialPublicOffering": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ProceedsFromIssuanceInitialPublicOffering",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Net proceed",
        "documentation": "The cash inflow associated with the amount received from entity's first offering of stock to the public."
       }
      }
     },
     "auth_ref": [
      "r2"
     ]
    },
    "us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss": {
       "parentTag": "us-gaap_NetIncomeLoss",
       "weight": 1.0,
       "order": 1.0
      }
     },
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails",
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "totalLabel": "Net loss before provision for income taxes",
        "label": "Total",
        "documentation": "Amount of income (loss) from continuing operations, including income (loss) from equity method investments, before deduction of income tax expense (benefit), and income (loss) attributable to noncontrolling interest."
       }
      }
     },
     "auth_ref": [
      "r0",
      "r61",
      "r81",
      "r138",
      "r145",
      "r147",
      "r149",
      "r285",
      "r292",
      "r391"
     ]
    },
    "us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StockIssuedDuringPeriodSharesStockOptionsExercised",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "negatedLabel": "Number of options, Exercised",
        "label": "Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period",
        "documentation": "Number of share options (or share units) exercised during the current period."
       }
      }
     },
     "auth_ref": [
      "r9",
      "r52",
      "r53",
      "r72",
      "r187"
     ]
    },
    "us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Aggregate intrinsic value, Exercisable",
        "documentation": "Amount of difference between fair value of the underlying shares reserved for issuance and exercise price of vested portions of options outstanding and currently exercisable."
       }
      }
     },
     "auth_ref": [
      "r33"
     ]
    },
    "us-gaap_PrepaidExpenseAndOtherAssetsCurrent": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "PrepaidExpenseAndOtherAssetsCurrent",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/BalanceSheets": {
       "parentTag": "us-gaap_Assets",
       "weight": 1.0,
       "order": 3.0
      }
     },
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Prepaid expenses and other current assets",
        "documentation": "Amount of asset related to consideration paid in advance for costs that provide economic benefits in future periods, and amount of other assets that are expected to be realized or consumed within one year or the normal operating cycle, if longer."
       }
      }
     },
     "auth_ref": [
      "r429"
     ]
    },
    "avxl_ResearchAndDevelopmentTaxCreditsYear": {
     "xbrltype": "stringItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "ResearchAndDevelopmentTaxCreditsYear",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Research and development tax credits year"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_MichaelJFoxFoundationMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "MichaelJFoxFoundationMember",
     "presentation": [
      "http://anavex.com/role/OtherIncomeDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Michael J Fox Foundation [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "dei_AuditedAnnualFinancialStatements": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "AuditedAnnualFinancialStatements",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Audited Annual Financial Statements",
        "documentation": "Boolean flag with value true on a form if it is an annual report containing audited financial statements."
       }
      }
     },
     "auth_ref": [
      "r420"
     ]
    },
    "avxl_PurchaseAgreement2019Member": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "PurchaseAgreement2019Member",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Purchase Agreement 2019 [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "dei_DocumentRegistrationStatement": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "DocumentRegistrationStatement",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Document Registration Statement",
        "documentation": "Boolean flag that is true only for a form used as a registration statement."
       }
      }
     },
     "auth_ref": [
      "r406"
     ]
    },
    "avxl_EquityOfferingSalesAgreementMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "EquityOfferingSalesAgreementMember",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Equity Offering Sales Agreement [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "WeightedAverageNumberOfDilutedSharesOutstanding",
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLossParenthetical"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Weighted average number of shares outstanding, Diluted",
        "documentation": "The average number of shares or units issued and outstanding that are used in calculating diluted EPS or earnings per unit (EPU), determined based on the timing of issuance of shares or units in the period."
       }
      }
     },
     "auth_ref": [
      "r126",
      "r132"
     ]
    },
    "avxl_SecuritiesPurchaseAgreementMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "SecuritiesPurchaseAgreementMember",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Securities Purchase Agreement [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_CommitmentSharesMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "CommitmentSharesMember",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Commitment Shares [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "dei_EntityAddressAddressLine1": {
     "xbrltype": "normalizedStringItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityAddressAddressLine1",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Address, Address Line One",
        "documentation": "Address Line 1 such as Attn, Building Name, Street Name"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_PurchaseAgreement2023Member": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "PurchaseAgreement2023Member",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Purchase Agreement 2023 [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "srt_CurrencyAxis": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/srt/2023",
     "localname": "CurrencyAxis",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative",
      "http://anavex.com/role/OtherIncomeDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Currency [Axis]"
       }
      }
     },
     "auth_ref": [
      "r477"
     ]
    },
    "us-gaap_WeightedAverageNumberOfSharesOutstandingBasic": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "WeightedAverageNumberOfSharesOutstandingBasic",
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLossParenthetical"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Weighted average number of shares outstanding, Basic",
        "documentation": "Number of [basic] shares or units, after adjustment for contingently issuable shares or units and other shares or units not deemed outstanding, determined by relating the portion of time within a reporting period that common shares or units have been outstanding to the total time in that period."
       }
      }
     },
     "auth_ref": [
      "r125",
      "r132"
     ]
    },
    "dei_LegalEntityAxis": {
     "xbrltype": "stringItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "LegalEntityAxis",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Legal Entity [Axis]",
        "documentation": "The set of legal entities associated with a report."
       }
      }
     },
     "auth_ref": []
    },
    "avxl_LincolnParkCapitalFundLLCMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "LincolnParkCapitalFundLLCMember",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Lincoln Park Capital Fund L L C [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_AssetsCurrentAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "AssetsCurrentAbstract",
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Current"
       }
      }
     },
     "auth_ref": []
    },
    "dei_EntityAddressAddressLine2": {
     "xbrltype": "normalizedStringItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityAddressAddressLine2",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Address, Address Line Two",
        "documentation": "Address Line 2 such as Street or Suite number"
       }
      }
     },
     "auth_ref": []
    },
    "dei_DocumentShellCompanyEventDate": {
     "xbrltype": "dateItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "DocumentShellCompanyEventDate",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Document Shell Company Event Date",
        "documentation": "Date of event requiring a shell company report."
       }
      }
     },
     "auth_ref": [
      "r419"
     ]
    },
    "dei_EntityInteractiveDataCurrent": {
     "xbrltype": "yesNoItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityInteractiveDataCurrent",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Interactive Data Current",
        "documentation": "Boolean flag that is true when the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit such files)."
       }
      }
     },
     "auth_ref": [
      "r423"
     ]
    },
    "dei_EntityDomain": {
     "xbrltype": "domainItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityDomain",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "All the names of the entities being reported upon in a document. Any legal structure used to conduct activities or to hold assets. Some examples of such structures are corporations, partnerships, limited liability companies, grantor trusts, and other trusts. This item does not include business and geographical segments which are included in the geographical or business segments domains."
       }
      }
     },
     "auth_ref": []
    },
    "avxl_CommonStockIncludingCommitmentSharesMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "CommonStockIncludingCommitmentSharesMember",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Common Stock Including Commitment Shares [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "dei_DocumentFinStmtErrorCorrectionFlag": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "DocumentFinStmtErrorCorrectionFlag",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Document Financial Statement Error Correction [Flag]",
        "documentation": "Indicates whether any of the financial statement period in the filing include a restatement due to error correction."
       }
      }
     },
     "auth_ref": [
      "r417",
      "r419",
      "r420",
      "r422"
     ]
    },
    "avxl_CommonStockExcludingCommitmentSharesMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "CommonStockExcludingCommitmentSharesMember",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Common Stock Excluding Commitment Shares [Member]"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_CommitmentsAndContingenciesDisclosureAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CommitmentsAndContingenciesDisclosureAbstract",
     "lang": {
      "en-us": {
       "role": {
        "label": "Commitments and Contingencies Disclosure [Abstract]"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_OffsettingAssetsTable": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "OffsettingAssetsTable",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3",
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Offsetting Assets [Table]",
        "documentation": "Disclosure of information about derivative and financial assets that are subject to offsetting, including enforceable master netting arrangements."
       }
      }
     },
     "auth_ref": [
      "r59",
      "r60"
     ]
    },
    "us-gaap_FairValueMeasurementPolicyPolicyTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "FairValueMeasurementPolicyPolicyTextBlock",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Fair Value Measurements",
        "documentation": "Disclosure of accounting policy for fair value measurements of financial and non-financial assets, liabilities and instruments classified in shareholders' equity. Disclosures include, but are not limited to, how an entity that manages a group of financial assets and liabilities on the basis of its net exposure measures the fair value of those assets and liabilities."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ClassOfWarrantOrRightOutstanding": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ClassOfWarrantOrRightOutstanding",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Warrants outstanding",
        "documentation": "Number of warrants or rights outstanding."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "DeferredTaxAssetsTaxCreditCarryforwardsResearch",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "verboseLabel": "Research and development tax credit carryforwards",
        "label": "Deferred Tax Assets, Tax Credit Carryforwards, Research",
        "documentation": "Amount before allocation of valuation allowances of deferred tax asset attributable to deductible research tax credit carryforwards."
       }
      }
     },
     "auth_ref": [
      "r41",
      "r42",
      "r473"
     ]
    },
    "us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Foreign Currency Translation",
        "documentation": "Disclosure of accounting policy for (1) transactions denominated in a currency other than the reporting enterprise's functional currency, (2) translating foreign currency financial statements that are incorporated into the financial statements of the reporting enterprise by consolidation, combination, or the equity method of accounting, and (3) remeasurement of the financial statements of a foreign reporting enterprise in a hyperinflationary economy."
       }
      }
     },
     "auth_ref": [
      "r253"
     ]
    },
    "avxl_EarningPerShareBasicAndDilutedAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "EarningPerShareBasicAndDilutedAbstract",
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Net Loss per share Basic and diluted"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_NoncashFinancingRelatedCharges": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "NoncashFinancingRelatedCharges",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/StatementsOfCashFlows": {
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": 1.0,
       "order": 2.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Non-cash financing related charges"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_Liabilities": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "Liabilities",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/BalanceSheets": {
       "parentTag": "us-gaap_LiabilitiesAndStockholdersEquity",
       "weight": 1.0,
       "order": 1.0
      }
     },
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "totalLabel": "Total Liabilities",
        "label": "Liabilities",
        "documentation": "Sum of the carrying amounts as of the balance sheet date of all liabilities that are recognized. Liabilities are probable future sacrifices of economic benefits arising from present obligations of an entity to transfer assets or provide services to other entities in the future."
       }
      }
     },
     "auth_ref": [
      "r15",
      "r109",
      "r151",
      "r160",
      "r161",
      "r162",
      "r163",
      "r164",
      "r165",
      "r166",
      "r167",
      "r168",
      "r240",
      "r241",
      "r242",
      "r252",
      "r330",
      "r390",
      "r405",
      "r442",
      "r481",
      "r482"
     ]
    },
    "avxl_DeferredGrantIncome": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "DeferredGrantIncome",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/StatementsOfCashFlows": {
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": -1.0,
       "order": 8.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "negatedLabel": "Deferred grant income",
        "label": "DeferredGrantIncome"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ForeignCountryMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ForeignCountryMember",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Foreign Tax Authority [Member]",
        "documentation": "Designated tax departments of governments entitled to levy and collect income taxes from the entity outside the entity's country of domicile."
       }
      }
     },
     "auth_ref": []
    },
    "avxl_CommitmentShares": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "CommitmentShares",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Commitment shares"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_StockIssuedDuringPeriodValueOther": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StockIssuedDuringPeriodValueOther",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Amount of shares remain available",
        "documentation": "Value of shares of stock issued attributable to transactions classified as other."
       }
      }
     },
     "auth_ref": []
    },
    "avxl_CashPaidForStateAndLocalMinimumIncomeTaxes": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "CashPaidForStateAndLocalMinimumIncomeTaxes",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Cash paid for state and local minimum income taxes"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails1"
     ],
     "lang": {
      "en-us": {
       "role": {
        "verboseLabel": "Stock-based compensation",
        "label": "Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost",
        "documentation": "Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from share-based compensation."
       }
      }
     },
     "auth_ref": [
      "r42",
      "r473"
     ]
    },
    "us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Loss per share for potentially dilutive common shares",
        "documentation": "Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented."
       }
      }
     },
     "auth_ref": [
      "r133"
     ]
    },
    "avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "SharesIssuedUnder2023PurchaseAgreementInitialCommitmentShares",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Shares issued under 2023 purchase agreement Initial Commitment shares"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "SharesIssuedUnder2023PurchaseAgreementInitialCommitmentSharesShares",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Shares issued under 2023 purchase agreement Initial Commitment shares, shares"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Change in valuation allowances",
        "documentation": "Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to increase (decrease) in the valuation allowance for deferred tax assets."
       }
      }
     },
     "auth_ref": [
      "r471"
     ]
    },
    "us-gaap_StatementOfFinancialPositionAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StatementOfFinancialPositionAbstract",
     "lang": {
      "en-us": {
       "role": {
        "label": "Statement of Financial Position [Abstract]"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_IncomeTaxDisclosureAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeTaxDisclosureAbstract",
     "lang": {
      "en-us": {
       "role": {
        "label": "Income Tax Disclosure [Abstract]"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_CommitmentSharesShares": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "CommitmentSharesShares",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Commitment shares, shares"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_LiabilitiesAndStockholdersEquity": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "LiabilitiesAndStockholdersEquity",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/BalanceSheets": {
       "parentTag": null,
       "weight": null,
       "order": null,
       "root": true
      }
     },
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "totalLabel": "Total Liabilities and Stockholders' Equity",
        "label": "Liabilities and Equity",
        "documentation": "Amount of liabilities and equity items, including the portion of equity attributable to noncontrolling interests, if any."
       }
      }
     },
     "auth_ref": [
      "r58",
      "r80",
      "r291",
      "r394",
      "r433",
      "r439",
      "r476"
     ]
    },
    "us-gaap_SubsequentEventsTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SubsequentEventsTextBlock",
     "presentation": [
      "http://anavex.com/role/SubsequentEvents"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Subsequent Events",
        "documentation": "The entire disclosure for significant events or transactions that occurred after the balance sheet date through the date the financial statements were issued or the date the financial statements were available to be issued. Examples include: the sale of a capital stock issue, purchase of a business, settlement of litigation, catastrophic loss, significant foreign exchange rate changes, loans to insiders or affiliates, and transactions not in the ordinary course of business."
       }
      }
     },
     "auth_ref": [
      "r269",
      "r270"
     ]
    },
    "us-gaap_LiabilitiesAndStockholdersEquityAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "LiabilitiesAndStockholdersEquityAbstract",
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Liabilities and Stockholders' Equity"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_SharesIssuedUnderSalesAgreement": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "SharesIssuedUnderSalesAgreement",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Shares issued under Sales Agreement"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_SharesIssuedPursuantToRegisteredDirectOfferingShares": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "SharesIssuedPursuantToRegisteredDirectOfferingShares",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Shares issued pursuant to registered direct offering, shares"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_IncreaseDecreaseInPrepaidExpense": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncreaseDecreaseInPrepaidExpense",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/StatementsOfCashFlows": {
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": -1.0,
       "order": 5.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "negatedLabel": "Prepaid expenses and deposits",
        "label": "Increase (Decrease) in Prepaid Expense",
        "documentation": "The increase (decrease) during the reporting period in the amount of outstanding money paid in advance for goods or services that bring economic benefits for future periods."
       }
      }
     },
     "auth_ref": [
      "r4"
     ]
    },
    "avxl_SharesIssuedUnderSalesAgreementShares": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "SharesIssuedUnderSalesAgreementShares",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Shares issued under Sales Agreement, shares"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_LessSalesAgreementShareIssueCosts": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "LessSalesAgreementShareIssueCosts",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Less: share issue costs"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_SharesIssuedPursuantToRegisteredDirectOffering": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "SharesIssuedPursuantToRegisteredDirectOffering",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Shares issued pursuant to registered direct offering"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract",
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Adjustments to reconcile net loss to net cash used in operations:"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_LessRegisteredDirectOfferingShareIssueCosts": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "LessRegisteredDirectOfferingShareIssueCosts",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "verboseLabel": "Less: share issue costs",
        "label": "LessRegisteredDirectOfferingShareIssueCosts"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_SharesIssuedPursuantToExerciseOfStockOptions": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "SharesIssuedPursuantToExerciseOfStockOptions",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Shares issued pursuant to exercise of stock options"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_SharesIssuedPursuantToExerciseOfStockOptionsShares": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "SharesIssuedPursuantToExerciseOfStockOptionsShares",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Shares issued pursuant to exercise of stock options, shares"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_SharesIssuedPusuantToExerciseOfWarrants": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "SharesIssuedPusuantToExerciseOfWarrants",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Shares issued pursuant to exercise of warrants"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2": {
     "xbrltype": "durationItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4",
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Weighted average remaining contractual life",
        "verboseLabel": "Weighted average contractual life of options outstanding",
        "documentation": "Weighted average remaining contractual term for option awards outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days."
       }
      }
     },
     "auth_ref": [
      "r73"
     ]
    },
    "us-gaap_DeferredTaxAssetsUnrealizedCurrencyLosses": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "DeferredTaxAssetsUnrealizedCurrencyLosses",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails1"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Foreign exchange and other",
        "documentation": "Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from unrealized losses on foreign currency transactions."
       }
      }
     },
     "auth_ref": [
      "r42",
      "r473"
     ]
    },
    "avxl_OperatingLossCarryforwardsDescription": {
     "xbrltype": "stringItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "OperatingLossCarryforwardsDescription",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Operating loss carryforwards description"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_SharesIssuedPusuantToExerciseOfWarrantsShares": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "SharesIssuedPusuantToExerciseOfWarrantsShares",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Shares issued pusuant to exercise of warrants, shares"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_DeferredTaxAssetsValuationAllowance": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "DeferredTaxAssetsValuationAllowance",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails1"
     ],
     "lang": {
      "en-us": {
       "role": {
        "negatedLabel": "Valuation allowance of deferred tax assets",
        "label": "Deferred Tax Assets, Valuation Allowance",
        "documentation": "Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized."
       }
      }
     },
     "auth_ref": [
      "r224"
     ]
    },
    "avxl_DisclosureAccruedLiabilitiesAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "DisclosureAccruedLiabilitiesAbstract",
     "lang": {
      "en-us": {
       "role": {
        "label": "Accrued Liabilities"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Remaining stock based compensation",
        "documentation": "Amount of cost to be recognized for option under share-based payment arrangement."
       }
      }
     },
     "auth_ref": [
      "r470"
     ]
    },
    "avxl_AccuredLiabilitiesTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "AccuredLiabilitiesTextBlock",
     "presentation": [
      "http://anavex.com/role/AccruedLiabilities"
     ],
     "lang": {
      "en-us": {
       "role": {
        "verboseLabel": "Accrued Liabilities",
        "label": "AccuredLiabilitiesTextBlock"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_EarningsPerSharePolicyTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "EarningsPerSharePolicyTextBlock",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Basic and Diluted Loss per Share",
        "documentation": "Disclosure of accounting policy for computing basic and diluted earnings or loss per share for each class of common stock and participating security. Addresses all significant policy factors, including any antidilutive items that have been excluded from the computation and takes into account stock dividends, splits and reverse splits that occur after the balance sheet date of the latest reporting period but before the issuance of the financial statements."
       }
      }
     },
     "auth_ref": [
      "r23",
      "r24"
     ]
    },
    "us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1": {
     "xbrltype": "durationItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails6"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Expected life of options (years)",
        "documentation": "Expected term of award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days."
       }
      }
     },
     "auth_ref": [
      "r200"
     ]
    },
    "us-gaap_AssetsAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "AssetsAbstract",
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Assets"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_DisclosureOtherIncomeAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "DisclosureOtherIncomeAbstract",
     "lang": {
      "en-us": {
       "role": {
        "label": "Other Income"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ForeignCurrencyTransactionGainLossBeforeTax": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ForeignCurrencyTransactionGainLossBeforeTax",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss": {
       "parentTag": "us-gaap_NonoperatingIncomeExpense",
       "weight": 1.0,
       "order": 5.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Foreign exchange loss",
        "documentation": "Amount, before tax, of realized and unrealized gain (loss) from foreign currency transaction."
       }
      }
     },
     "auth_ref": [
      "r254",
      "r255",
      "r256",
      "r257",
      "r370"
     ]
    },
    "us-gaap_AccountsPayableCurrent": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "AccountsPayableCurrent",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/BalanceSheets": {
       "parentTag": "us-gaap_Liabilities",
       "weight": 1.0,
       "order": 1.0
      }
     },
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Accounts payable",
        "documentation": "Carrying value as of the balance sheet date of liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received that are used in an entity's business. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer)."
       }
      }
     },
     "auth_ref": [
      "r14",
      "r394"
     ]
    },
    "avxl_OtherIncomeDisclosureTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "OtherIncomeDisclosureTextBlock",
     "presentation": [
      "http://anavex.com/role/OtherIncome"
     ],
     "lang": {
      "en-us": {
       "role": {
        "verboseLabel": "Other Income",
        "label": "OtherIncomeDisclosureTextBlock"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_LicenseFeesPolicyTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "LicenseFeesPolicyTextBlock",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "License Fees"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_DisclosureEquityOfferingsAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "DisclosureEquityOfferingsAbstract",
     "lang": {
      "en-us": {
       "role": {
        "label": "Equity Offerings"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_EquityOfferingTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "EquityOfferingTextBlock",
     "presentation": [
      "http://anavex.com/role/EquityOfferings"
     ],
     "lang": {
      "en-us": {
       "role": {
        "verboseLabel": "Equity Offerings",
        "label": "EquityOfferingTextBlock"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_StatementLineItems": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StatementLineItems",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative",
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Statement [Line Items]",
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table."
       }
      }
     },
     "auth_ref": [
      "r112",
      "r113",
      "r114",
      "r135",
      "r271",
      "r302",
      "r321",
      "r324",
      "r325",
      "r326",
      "r327",
      "r328",
      "r329",
      "r332",
      "r335",
      "r336",
      "r337",
      "r338",
      "r339",
      "r341",
      "r342",
      "r343",
      "r344",
      "r346",
      "r347",
      "r348",
      "r349",
      "r350",
      "r352",
      "r355",
      "r356",
      "r358",
      "r359",
      "r360",
      "r361",
      "r362",
      "r363",
      "r364",
      "r365",
      "r366",
      "r367",
      "r368",
      "r369",
      "r373",
      "r398"
     ]
    },
    "us-gaap_NetCashProvidedByUsedInFinancingActivities": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "NetCashProvidedByUsedInFinancingActivities",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/StatementsOfCashFlows": {
       "parentTag": "us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect",
       "weight": 1.0,
       "order": 2.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "totalLabel": "Net cash provided by financing activities",
        "label": "Net Cash Provided by (Used in) Financing Activities",
        "documentation": "Amount of cash inflow (outflow) from financing activities, including discontinued operations. Financing activity cash flows include obtaining resources from owners and providing them with a return on, and a return of, their investment; borrowing money and repaying amounts borrowed, or settling the obligation; and obtaining and paying for other resources obtained from creditors on long-term credit."
       }
      }
     },
     "auth_ref": [
      "r106"
     ]
    },
    "dei_EntityShellCompany": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityShellCompany",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Shell Company",
        "documentation": "Boolean flag that is true when the registrant is a shell company as defined in Rule 12b-2 of the Exchange Act."
       }
      }
     },
     "auth_ref": [
      "r408"
     ]
    },
    "us-gaap_OperatingLossCarryforwardsTable": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "OperatingLossCarryforwardsTable",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Operating Loss Carryforwards [Table]",
        "documentation": "Schedule reflecting pertinent information, such as tax authority, amounts, and expiration dates, of net operating loss carryforwards, including an assessment of the likelihood of utilization."
       }
      }
     },
     "auth_ref": [
      "r40"
     ]
    },
    "dei_Security12gTitle": {
     "xbrltype": "securityTitleItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "Security12gTitle",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Title of 12(g) Security",
        "documentation": "Title of a 12(g) registered security."
       }
      }
     },
     "auth_ref": [
      "r411"
     ]
    },
    "currency_AllCurrenciesDomain": {
     "xbrltype": "domainItemType",
     "nsuri": "http://xbrl.sec.gov/currency/2023",
     "localname": "AllCurrenciesDomain",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative",
      "http://anavex.com/role/OtherIncomeDetailsNarrative"
     ],
     "auth_ref": []
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3",
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "periodStartLabel": "Weighted average exercise price, Outstanding beginning balance",
        "periodEndLabel": "Weighted average exercise price, Outstanding ending balance",
        "label": "Weighted average exercise price",
        "documentation": "Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan."
       }
      }
     },
     "auth_ref": [
      "r182",
      "r183"
     ]
    },
    "us-gaap_IncomeTaxReconciliationPriorYearIncomeTaxes": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeTaxReconciliationPriorYearIncomeTaxes",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Adjustment to true up to prior years' tax provision",
        "documentation": "Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to revisions of previously reported income tax expense (benefit)."
       }
      }
     },
     "auth_ref": [
      "r471"
     ]
    },
    "us-gaap_AdditionalPaidInCapitalMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "AdditionalPaidInCapitalMember",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Additional Paid-in Capital [Member]",
        "documentation": "Excess of issue price over par or stated value of the entity's capital stock and amounts received from other transactions involving the entity's stock or stockholders."
       }
      }
     },
     "auth_ref": [
      "r207",
      "r208",
      "r209",
      "r310",
      "r435",
      "r436",
      "r437",
      "r474",
      "r485"
     ]
    },
    "us-gaap_StockRepurchasedDuringPeriodValue": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StockRepurchasedDuringPeriodValue",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Purchase shares",
        "documentation": "Equity impact of the value of stock that has been repurchased during the period and has not been retired and is not held in treasury. Some state laws may mandate the circumstances under which an entity may acquire its own stock and prescribe the accounting treatment therefore. This element is used when state law does not recognize treasury stock."
       }
      }
     },
     "auth_ref": [
      "r9",
      "r52",
      "r53",
      "r72",
      "r310",
      "r373",
      "r384",
      "r404"
     ]
    },
    "dei_EntityFilerCategory": {
     "xbrltype": "filerCategoryItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityFilerCategory",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Filer Category",
        "documentation": "Indicate whether the registrant is one of the following: Large Accelerated Filer, Accelerated Filer, Non-accelerated Filer. Definitions of these categories are stated in Rule 12b-2 of the Exchange Act. This information should be based on the registrant's current or most recent filing containing the related disclosure."
       }
      }
     },
     "auth_ref": [
      "r408"
     ]
    },
    "dei_LocalPhoneNumber": {
     "xbrltype": "normalizedStringItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "LocalPhoneNumber",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Local Phone Number",
        "documentation": "Local phone number for entity."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_IncomeTaxReconciliationOtherAdjustments": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeTaxReconciliationOtherAdjustments",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Other permanent differences",
        "documentation": "Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to other adjustments."
       }
      }
     },
     "auth_ref": [
      "r471"
     ]
    },
    "us-gaap_AccruedBonusesCurrent": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "AccruedBonusesCurrent",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/AccruedLiabilitiesDetails": {
       "parentTag": "us-gaap_AccruedLiabilitiesCurrent",
       "weight": 1.0,
       "order": 2.0
      }
     },
     "presentation": [
      "http://anavex.com/role/AccruedLiabilitiesDetails"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Accrued compensation and benefits",
        "documentation": "Carrying value as of the balance sheet date of obligations incurred and payable for incentive compensation awarded to employees and directors or earned by them based on the terms of one or more relevant arrangements. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer)."
       }
      }
     },
     "auth_ref": [
      "r16"
     ]
    },
    "avxl_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentCreditNet",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Research and development credits, net"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_NetCashProvidedByUsedInOperatingActivities": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "NetCashProvidedByUsedInOperatingActivities",
     "calculation": {
      "http://anavex.com/role/StatementsOfCashFlows": {
       "parentTag": "us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect",
       "weight": 1.0,
       "order": 1.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "totalLabel": "Net cash used in operating activities",
        "label": "Net Cash Provided by (Used in) Operating Activities",
        "documentation": "Amount of cash inflow (outflow) from operating activities, including discontinued operations. Operating activity cash flows include transactions, adjustments, and changes in value not defined as investing or financing activities."
       }
      }
     },
     "auth_ref": [
      "r66",
      "r67",
      "r68"
     ]
    },
    "us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeTaxReconciliationStateAndLocalIncomeTaxes",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "State and local taxes",
        "documentation": "Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to state and local income tax expense (benefit)."
       }
      }
     },
     "auth_ref": [
      "r471"
     ]
    },
    "dei_SecurityReportingObligation": {
     "xbrltype": "securityReportingObligationItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "SecurityReportingObligation",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Security Reporting Obligation",
        "documentation": "15(d), indicating whether the security has a reporting obligation under that section of the Exchange Act."
       }
      }
     },
     "auth_ref": [
      "r415"
     ]
    },
    "avxl_PermanentDifferencesRelatingToStockBasedCompensation": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "PermanentDifferencesRelatingToStockBasedCompensation",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Permanent differences relating to stock based compensation"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_GrantIncomePolicyTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "GrantIncomePolicyTextBlock",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Grant Income"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_PermanentDifferencesRelatingToSection162m": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "PermanentDifferencesRelatingToSection162m",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Permanent differences relating to Section 162(m)"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Weighted average exercise price, Granted",
        "documentation": "Weighted average per share amount at which grantees can acquire shares of common stock by exercise of options."
       }
      }
     },
     "auth_ref": [
      "r186"
     ]
    },
    "dei_EntitySmallBusiness": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntitySmallBusiness",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Small Business",
        "documentation": "Indicates that the company is a Smaller Reporting Company (SRC)."
       }
      }
     },
     "auth_ref": [
      "r408"
     ]
    },
    "us-gaap_PensionContributions": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "PensionContributions",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails1"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Contributions to 401(k) plan",
        "documentation": "Amount of cash outflow for pension benefit. Includes, but is not limited to, employer contribution to fund plan asset and payment to retiree. Excludes other postretirement benefit."
       }
      }
     },
     "auth_ref": [
      "r3"
     ]
    },
    "avxl_DeferredTaxAssetsResearchAndDevelopmentCapitalization": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "DeferredTaxAssetsResearchAndDevelopmentCapitalization",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails1"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Research and development capitalization"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_AdjustmentToTaxAssetsBasedOnSection382": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "AdjustmentToTaxAssetsBasedOnSection382",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Adjustment to tax assets based on Section 382"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_FixedContractAccruals": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "FixedContractAccruals",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/AccruedLiabilitiesDetails": {
       "parentTag": "us-gaap_AccruedLiabilitiesCurrent",
       "weight": 1.0,
       "order": 3.0
      }
     },
     "presentation": [
      "http://anavex.com/role/AccruedLiabilitiesDetails"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Fixed contract accruals"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Weighted average exercise price, Exercised",
        "documentation": "Weighted average price at which option holders acquired shares when converting their stock options into shares."
       }
      }
     },
     "auth_ref": [
      "r187"
     ]
    },
    "avxl_ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "ScheduleOfSharePurchaseWarrantsOutstandingTableTextBlock",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesTables"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Schedule of share purchase warrants outstanding"
       }
      }
     },
     "auth_ref": []
    },
    "dei_EntityCommonStockSharesOutstanding": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityCommonStockSharesOutstanding",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Common Stock, Shares Outstanding",
        "documentation": "Indicate number of shares or other units outstanding of each of registrant's classes of capital or common stock or other ownership interests, if and as stated on cover of related periodic report. Where multiple classes or units exist define each class/interest by adding class of stock items such as Common Class A [Member], Common Class B [Member] or Partnership Interest [Member] onto the Instrument [Domain] of the Entity Listings, Instrument."
       }
      }
     },
     "auth_ref": []
    },
    "avxl_ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "ScheduleOfShareBasedPaymentWeightedAverageValuationAssumptionsTableTextBlock",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesTables"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Schedule of weighted average assumptions for fair value of each option award"
       }
      }
     },
     "auth_ref": []
    },
    "dei_EntityEmergingGrowthCompany": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityEmergingGrowthCompany",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Emerging Growth Company",
        "documentation": "Indicate if registrant meets the emerging growth company criteria."
       }
      }
     },
     "auth_ref": [
      "r408"
     ]
    },
    "dei_CoverAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "CoverAbstract",
     "lang": {
      "en-us": {
       "role": {
        "label": "Cover [Abstract]",
        "documentation": "Cover page."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_OperatingLossCarryforwardsLineItems": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "OperatingLossCarryforwardsLineItems",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Operating Loss Carryforwards [Line Items]",
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table."
       }
      }
     },
     "auth_ref": []
    },
    "avxl_AccruedClinicalSiteAndPatientVisitsCosts": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "AccruedClinicalSiteAndPatientVisitsCosts",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/AccruedLiabilitiesDetails": {
       "parentTag": "us-gaap_AccruedLiabilitiesCurrent",
       "weight": 1.0,
       "order": 1.0
      }
     },
     "presentation": [
      "http://anavex.com/role/AccruedLiabilitiesDetails"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Accrued clinical site and patient visits costs"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_StatementEquityComponentsAxis": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StatementEquityComponentsAxis",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Equity Components [Axis]",
        "documentation": "Information by component of equity."
       }
      }
     },
     "auth_ref": [
      "r9",
      "r19",
      "r91",
      "r102",
      "r103",
      "r104",
      "r112",
      "r113",
      "r114",
      "r116",
      "r122",
      "r124",
      "r135",
      "r152",
      "r153",
      "r174",
      "r207",
      "r208",
      "r209",
      "r229",
      "r230",
      "r243",
      "r244",
      "r245",
      "r246",
      "r247",
      "r248",
      "r249",
      "r258",
      "r259",
      "r260",
      "r261",
      "r262",
      "r263",
      "r266",
      "r295",
      "r296",
      "r297",
      "r310",
      "r373"
     ]
    },
    "us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Weighted average exercise price, Forfeited",
        "documentation": "Weighted average price at which grantees could have acquired the underlying shares with respect to stock options that were terminated."
       }
      }
     },
     "auth_ref": [
      "r188"
     ]
    },
    "us-gaap_RetainedEarningsMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "RetainedEarningsMember",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Retained Earnings [Member]",
        "documentation": "Accumulated undistributed earnings (deficit)."
       }
      }
     },
     "auth_ref": [
      "r91",
      "r112",
      "r113",
      "r114",
      "r116",
      "r122",
      "r124",
      "r152",
      "r153",
      "r207",
      "r208",
      "r209",
      "r229",
      "r230",
      "r243",
      "r245",
      "r246",
      "r248",
      "r249",
      "r295",
      "r297",
      "r310",
      "r485"
     ]
    },
    "dei_EntityExTransitionPeriod": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityExTransitionPeriod",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Elected Not To Use the Extended Transition Period",
        "documentation": "Indicate if an emerging growth company has elected not to use the extended transition period for complying with any new or revised financial accounting standards."
       }
      }
     },
     "auth_ref": [
      "r426"
     ]
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "periodStartLabel": "Weighted average grant date fair value, Outstanding beginning balance",
        "periodEndLabel": "Weighted average grant date fair value, Outstanding ending balance",
        "label": "Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value",
        "documentation": "Per share or unit weighted-average fair value of nonvested award under share-based payment arrangement. Excludes share and unit options."
       }
      }
     },
     "auth_ref": [
      "r190",
      "r191"
     ]
    },
    "avxl_MilestoneBasedContractAccruals": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "MilestoneBasedContractAccruals",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/AccruedLiabilitiesDetails": {
       "parentTag": "us-gaap_AccruedLiabilitiesCurrent",
       "weight": 1.0,
       "order": 4.0
      }
     },
     "presentation": [
      "http://anavex.com/role/AccruedLiabilitiesDetails"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Milestone based contract accruals"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_DeferredIncomeTaxExpenseBenefit": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "DeferredIncomeTaxExpenseBenefit",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Income tax expense",
        "documentation": "Amount of deferred income tax expense (benefit) pertaining to income (loss) from continuing operations."
       }
      }
     },
     "auth_ref": [
      "r5",
      "r77",
      "r89",
      "r232",
      "r233",
      "r434"
     ]
    },
    "avxl_NonOperatingIncomeFromGrant": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "NonOperatingIncomeFromGrant",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/OtherIncomeDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Non operating income from grant"
       }
      }
     },
     "auth_ref": []
    },
    "dei_EntityPublicFloat": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityPublicFloat",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Public Float",
        "documentation": "The aggregate market value of the voting and non-voting common equity held by non-affiliates computed by reference to the price at which the common equity was last sold, or the average bid and asked price of such common equity, as of the last business day of the registrant's most recently completed second fiscal quarter."
       }
      }
     },
     "auth_ref": []
    },
    "avxl_GrantIncome": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "GrantIncome",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/OtherIncomeDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "verboseLabel": "Grant income",
        "label": "GrantIncome"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesTables"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Schedule of components of net deferred income tax assets",
        "documentation": "Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets."
       }
      }
     },
     "auth_ref": [
      "r76"
     ]
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Weighted average grant date fair value of options vested",
        "documentation": "The weighted average fair value as of grant date pertaining to an equity-based award plan other than a stock (or unit) option plan for which the grantee gained the right during the reporting period, by satisfying service and performance requirements, to receive or retain shares or units, other instruments, or cash in accordance with the terms of the arrangement."
       }
      }
     },
     "auth_ref": [
      "r194"
     ]
    },
    "us-gaap_AccruedLiabilitiesCurrent": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "AccruedLiabilitiesCurrent",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/BalanceSheets": {
       "parentTag": "us-gaap_Liabilities",
       "weight": 1.0,
       "order": 2.0
      },
      "http://anavex.com/role/AccruedLiabilitiesDetails": {
       "parentTag": null,
       "weight": null,
       "order": null,
       "root": true
      }
     },
     "presentation": [
      "http://anavex.com/role/AccruedLiabilitiesDetails",
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Accrued liabilities - Note 3",
        "totalLabel": "Total accrued liabilities",
        "documentation": "Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer)."
       }
      }
     },
     "auth_ref": [
      "r16"
     ]
    },
    "us-gaap_SupplementalCashFlowInformationAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SupplementalCashFlowInformationAbstract",
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Supplemental Cash Flow Information"
       }
      }
     },
     "auth_ref": []
    },
    "dei_OtherReportingStandardItemNumber": {
     "xbrltype": "otherReportingStandardItemNumberItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "OtherReportingStandardItemNumber",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Other Reporting Standard Item Number",
        "documentation": "\"Item 17\" or \"Item 18\" specified when the basis of accounting is neither US GAAP nor IFRS."
       }
      }
     },
     "auth_ref": [
      "r419"
     ]
    },
    "us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesTables"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Schedule of reconciliation of income tax expense",
        "documentation": "Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations."
       }
      }
     },
     "auth_ref": [
      "r75"
     ]
    },
    "avxl_WarrantsOutstandingWeightedAverageExercise": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "WarrantsOutstandingWeightedAverageExercise",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Warrants outstanding weighted average exercise price"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesTables"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Schedule of loss before income taxes",
        "documentation": "Tabular disclosure of income before income tax between domestic and foreign jurisdictions."
       }
      }
     },
     "auth_ref": [
      "r434"
     ]
    },
    "avxl_DeferredGrantIncome1": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "DeferredGrantIncome1",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/OtherIncomeDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Deferred grant income"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_EquityComponentDomain": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "EquityComponentDomain",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Components of equity are the parts of the total Equity balance including that which is allocated to common, preferred, treasury stock, retained earnings, etc."
       }
      }
     },
     "auth_ref": [
      "r9",
      "r91",
      "r102",
      "r103",
      "r104",
      "r112",
      "r113",
      "r114",
      "r116",
      "r122",
      "r124",
      "r135",
      "r152",
      "r153",
      "r174",
      "r207",
      "r208",
      "r209",
      "r229",
      "r230",
      "r243",
      "r244",
      "r245",
      "r246",
      "r247",
      "r248",
      "r249",
      "r258",
      "r259",
      "r260",
      "r261",
      "r262",
      "r263",
      "r266",
      "r295",
      "r296",
      "r297",
      "r310",
      "r373"
     ]
    },
    "us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Supplementary information on outstanding and exercisable share awards as of the balance sheet date which stratifies outstanding options by ranges of exercise prices."
       }
      }
     },
     "auth_ref": [
      "r36"
     ]
    },
    "avxl_PercentageOfGrossProceedsFromSales": {
     "xbrltype": "percentItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "PercentageOfGrossProceedsFromSales",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Percentage of gross proceeds from sales"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Exercise Price Range [Axis]",
        "documentation": "Information by range of option prices pertaining to options granted."
       }
      }
     },
     "auth_ref": [
      "r35"
     ]
    },
    "us-gaap_IncomeTaxesReceivable": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeTaxesReceivable",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/BalanceSheets": {
       "parentTag": "us-gaap_Assets",
       "weight": 1.0,
       "order": 2.0
      }
     },
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Incentive and tax receivables",
        "documentation": "Carrying amount due within one year of the balance sheet date (or one operating cycle, if longer) from tax authorities as of the balance sheet date representing refunds of overpayments or recoveries based on agreed-upon resolutions of disputes."
       }
      }
     },
     "auth_ref": [
      "r48",
      "r428"
     ]
    },
    "avxl_SoldForGrossProceedsAmount": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "SoldForGrossProceedsAmount",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Sold for gross proceeds amount"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_IncomeTaxAuthorityDomain": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeTaxAuthorityDomain",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Agency, division or body classification that levies income taxes, examines tax returns for compliance, or grants exemptions from or makes other decisions pertaining to income taxes."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Range of exercise prices, Lower range limit",
        "documentation": "The floor of a customized range of exercise prices for purposes of disclosing shares potentially issuable under outstanding stock option awards on all stock option plans and other required information pertaining to awards in the customized range."
       }
      }
     },
     "auth_ref": [
      "r36"
     ]
    },
    "us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Range of exercise prices, Upper range limit",
        "documentation": "The ceiling of a customized range of exercise prices for purposes of disclosing shares potentially issuable under outstanding stock option awards on all stock option plans and other required information pertaining to awards in the customized range."
       }
      }
     },
     "auth_ref": [
      "r36"
     ]
    },
    "us-gaap_OtherReceivables": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "OtherReceivables",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/OtherIncomeDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "verboseLabel": "Incentive and tax receivables",
        "label": "Other Receivables",
        "documentation": "Amount due from parties in nontrade transactions, classified as other."
       }
      }
     },
     "auth_ref": [
      "r98",
      "r340"
     ]
    },
    "us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ScheduleOfAccruedLiabilitiesTableTextBlock",
     "presentation": [
      "http://anavex.com/role/AccruedLiabilitiesTables"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Schedule of principal components of accrued liabilities",
        "documentation": "Tabular disclosure of the components of accrued liabilities."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_StockRepurchasedDuringPeriodShares": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StockRepurchasedDuringPeriodShares",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Purchase shares, shares",
        "documentation": "Number of shares that have been repurchased during the period and have not been retired and are not held in treasury. Some state laws may govern the circumstances under which an entity may acquire its own stock and prescribe the accounting treatment therefore. This element is used when state law does not recognize treasury stock."
       }
      }
     },
     "auth_ref": [
      "r9",
      "r52",
      "r53",
      "r72",
      "r307",
      "r373",
      "r384"
     ]
    },
    "avxl_SalesOfAgreementAmount": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "SalesOfAgreementAmount",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Sales of agreement amount"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_WarrantsAndRightsOutstandingMaturityDate": {
     "xbrltype": "dateItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "WarrantsAndRightsOutstandingMaturityDate",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Expiry Date",
        "documentation": "Expiration date of outstanding warrant and right embodying unconditional obligation requiring redemption by transferring asset at specified or determinable date or upon event certain to occur, in YYYY-MM-DD format."
       }
      }
     },
     "auth_ref": [
      "r475"
     ]
    },
    "us-gaap_SignificantAccountingPoliciesTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SignificantAccountingPoliciesTextBlock",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Summary of Significant Accounting Policies",
        "documentation": "The entire disclosure for all significant accounting policies of the reporting entity."
       }
      }
     },
     "auth_ref": [
      "r69",
      "r108"
     ]
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Option available issue",
        "documentation": "The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable."
       }
      }
     },
     "auth_ref": [
      "r33"
     ]
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Aggregate intrinsic value, Exercised",
        "documentation": "Amount of accumulated difference between fair value of underlying shares on dates of exercise and exercise price on options exercised (or share units converted) into shares."
       }
      }
     },
     "auth_ref": [
      "r197"
     ]
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "negatedLabel": "Number of options, Forfeited",
        "label": "Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period",
        "documentation": "The number of shares under options that were cancelled during the reporting period as a result of occurrence of a terminating event specified in contractual agreements pertaining to the stock option plan."
       }
      }
     },
     "auth_ref": [
      "r188"
     ]
    },
    "avxl_ValueOfSharesObligatedToPurchase": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "ValueOfSharesObligatedToPurchase",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Value of shares obligated to purchase"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_NumberOfSharesObligatedToPurchaseProrataBasic": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "NumberOfSharesObligatedToPurchaseProrataBasic",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Pro rata basic number of shares obligated to purchase"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Option granted",
        "documentation": "Net number of share options (or share units) granted during the period."
       }
      }
     },
     "auth_ref": [
      "r451"
     ]
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Weighted average grant date fair value, Granted",
        "documentation": "The weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology."
       }
      }
     },
     "auth_ref": [
      "r196"
     ]
    },
    "avxl_FairValueOfInitialCommitment": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "FairValueOfInitialCommitment",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Fair value of the initial commitment"
       }
      }
     },
     "auth_ref": []
    },
    "dei_DocumentsIncorporatedByReferenceTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "DocumentsIncorporatedByReferenceTextBlock",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Documents Incorporated by Reference [Text Block]",
        "documentation": "Documents incorporated by reference."
       }
      }
     },
     "auth_ref": [
      "r409"
     ]
    },
    "us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue",
     "crdr": "credit",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Share based compensation",
        "documentation": "Amount of increase to additional paid-in capital (APIC) for recognition of cost for award under share-based payment arrangement."
       }
      }
     },
     "auth_ref": [
      "r38",
      "r39",
      "r177"
     ]
    },
    "us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesTables"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Schedule of summarizes information about stock options",
        "documentation": "Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value."
       }
      }
     },
     "auth_ref": [
      "r10",
      "r11",
      "r34"
     ]
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "periodStartLabel": "Aggregate intrinsic value, Outstanding beginning balance",
        "periodEndLabel": "Aggregate intrinsic value, Outstanding ending balance",
        "label": "Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value",
        "documentation": "Amount by which the current fair value of the underlying stock exceeds the exercise price of options outstanding."
       }
      }
     },
     "auth_ref": [
      "r33"
     ]
    },
    "avxl_IncurredExpenses": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "IncurredExpenses",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Incurred expenses"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3",
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "periodStartLabel": "Number of options, Outstanding beginning balance",
        "periodEndLabel": "Number of options, Outstanding ending balance",
        "label": "Number of outstanding options",
        "documentation": "Number of options outstanding, including both vested and non-vested options."
       }
      }
     },
     "auth_ref": [
      "r182",
      "r183"
     ]
    },
    "avxl_DeferredTaxAssetsUnpaidCharges": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "DeferredTaxAssetsUnpaidCharges",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails1"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Unpaid charges"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_OperatingExpenses": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "OperatingExpenses",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss": {
       "parentTag": "us-gaap_OperatingIncomeLoss",
       "weight": -1.0,
       "order": 1.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "totalLabel": "Total operating expenses",
        "label": "Operating Expenses",
        "documentation": "Generally recurring costs associated with normal operations except for the portion of these expenses which can be clearly related to production and included in cost of sales or services. Includes selling, general and administrative expense."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Number of options, Exercisable",
        "documentation": "The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan."
       }
      }
     },
     "auth_ref": [
      "r184"
     ]
    },
    "avxl_OptionIssued": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "OptionIssued",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Option issued"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisesPrice",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Weighted average grant date fair value, Forfeited"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_OperatingExpensesAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "OperatingExpensesAbstract",
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Operating expenses"
       }
      }
     },
     "auth_ref": []
    },
    "avxl_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://anavex.com/20230930",
     "localname": "ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisesPrice",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Weighted average grant date fair value, Exercised"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Weighted average exercise price, Exercisable",
        "documentation": "The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and currently exercisable under the stock option plan."
       }
      }
     },
     "auth_ref": [
      "r184"
     ]
    },
    "us-gaap_StatementTable": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "StatementTable",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative",
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Statement [Table]",
        "documentation": "Schedule reflecting a Statement of Income, Statement of Cash Flows, Statement of Financial Position, Statement of Shareholders' Equity and Other Comprehensive Income, or other statement as needed."
       }
      }
     },
     "auth_ref": [
      "r112",
      "r113",
      "r114",
      "r135",
      "r271",
      "r302",
      "r321",
      "r324",
      "r325",
      "r326",
      "r327",
      "r328",
      "r329",
      "r332",
      "r335",
      "r336",
      "r337",
      "r338",
      "r339",
      "r341",
      "r342",
      "r343",
      "r344",
      "r346",
      "r347",
      "r348",
      "r349",
      "r350",
      "r352",
      "r355",
      "r356",
      "r358",
      "r359",
      "r360",
      "r361",
      "r362",
      "r363",
      "r364",
      "r365",
      "r366",
      "r367",
      "r368",
      "r369",
      "r373",
      "r398"
     ]
    },
    "us-gaap_DeferredRentCredit": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "DeferredRentCredit",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/BalanceSheets": {
       "parentTag": "us-gaap_Liabilities",
       "weight": 1.0,
       "order": 3.0
      }
     },
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Deferred grant income - Note 4",
        "documentation": "Amount of excess of rental payment required by lease over rental income recognized."
       }
      }
     },
     "auth_ref": [
      "r84",
      "r479"
     ]
    },
    "us-gaap_LeaseCostTableTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "LeaseCostTableTextBlock",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesTables"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Schedule of operating lease costs",
        "documentation": "Tabular disclosure of lessee's lease cost. Includes, but is not limited to, interest expense for finance lease, amortization of right-of-use asset for finance lease, operating lease cost, short-term lease cost, variable lease cost and sublease income."
       }
      }
     },
     "auth_ref": [
      "r478"
     ]
    },
    "us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "DeferredTaxAssetsGoodwillAndIntangibleAssets",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails1"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Intangible asset costs",
        "documentation": "Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from intangible assets including goodwill."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_OperatingLossCarryforwards": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "OperatingLossCarryforwards",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Operating loss carryforwards",
        "documentation": "Amount of operating loss carryforward, before tax effects, available to reduce future taxable income under enacted tax laws."
       }
      }
     },
     "auth_ref": [
      "r41"
     ]
    },
    "us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1": {
     "xbrltype": "durationItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "OperatingLeaseWeightedAverageRemainingLeaseTerm1",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Operating lease term",
        "documentation": "Weighted average remaining lease term for operating lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days."
       }
      }
     },
     "auth_ref": [
      "r265",
      "r393"
     ]
    },
    "us-gaap_OperatingIncomeLoss": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "OperatingIncomeLoss",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss": {
       "parentTag": "us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest",
       "weight": 1.0,
       "order": 1.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfOperationsAndComprehensiveLoss"
     ],
     "lang": {
      "en-us": {
       "role": {
        "totalLabel": "Operating loss",
        "label": "Operating Income (Loss)",
        "documentation": "The net result for the period of deducting operating expenses from operating revenues."
       }
      }
     },
     "auth_ref": [
      "r138",
      "r145",
      "r147",
      "r149",
      "r391"
     ]
    },
    "us-gaap_CommitmentsDisclosureTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "CommitmentsDisclosureTextBlock",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingencies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Commitments and Contingencies",
        "documentation": "The entire disclosure for significant arrangements with third parties, which includes operating lease arrangements and arrangements in which the entity has agreed to expend funds to procure goods or services, or has agreed to commit resources to supply goods or services, and operating lease arrangements. Descriptions may include identification of the specific goods and services, period of time covered, minimum quantities and amounts, and cancellation rights."
       }
      }
     },
     "auth_ref": [
      "r71"
     ]
    },
    "dei_WrittenCommunications": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "WrittenCommunications",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Written Communications",
        "documentation": "Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as written communications pursuant to Rule 425 under the Securities Act."
       }
      }
     },
     "auth_ref": [
      "r425"
     ]
    },
    "us-gaap_ArrangementsAndNonarrangementTransactionsMember": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ArrangementsAndNonarrangementTransactionsMember",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Collaborative arrangement and arrangement other than collaborative applicable to revenue-generating activity or operations."
       }
      }
     },
     "auth_ref": [
      "r238"
     ]
    },
    "us-gaap_DerivativeInstrumentRiskAxis": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "DerivativeInstrumentRiskAxis",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3",
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Derivative Instrument [Axis]",
        "documentation": "Information by type of derivative contract."
       }
      }
     },
     "auth_ref": [
      "r44",
      "r45",
      "r46",
      "r47",
      "r322",
      "r323",
      "r337",
      "r338",
      "r339",
      "r341",
      "r342",
      "r343",
      "r344",
      "r346",
      "r347",
      "r348",
      "r349",
      "r360",
      "r361",
      "r362",
      "r363",
      "r366",
      "r367",
      "r368",
      "r369",
      "r377",
      "r378",
      "r379",
      "r380",
      "r387",
      "r395",
      "r397"
     ]
    },
    "dei_SolicitingMaterial": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "SolicitingMaterial",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Soliciting Material",
        "documentation": "Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as soliciting material pursuant to Rule 14a-12 under the Exchange Act."
       }
      }
     },
     "auth_ref": [
      "r416"
     ]
    },
    "dei_PreCommencementTenderOffer": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "PreCommencementTenderOffer",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Pre-commencement Tender Offer",
        "documentation": "Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act."
       }
      }
     },
     "auth_ref": [
      "r414"
     ]
    },
    "us-gaap_TypeOfArrangementAxis": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "TypeOfArrangementAxis",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Collaborative Arrangement and Arrangement Other than Collaborative [Axis]",
        "documentation": "Information by collaborative arrangement and arrangement other than collaborative applicable to revenue-generating activity or operations."
       }
      }
     },
     "auth_ref": [
      "r238"
     ]
    },
    "dei_PreCommencementIssuerTenderOffer": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "PreCommencementIssuerTenderOffer",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Pre-commencement Issuer Tender Offer",
        "documentation": "Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act."
       }
      }
     },
     "auth_ref": [
      "r413"
     ]
    },
    "us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock",
     "presentation": [
      "http://anavex.com/role/BusinessDescriptionAndBasisOfPresentation"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Business Description and Basis of Presentation",
        "documentation": "The entire disclosure for organization, consolidation and basis of presentation of financial statements disclosure."
       }
      }
     },
     "auth_ref": [
      "r51",
      "r78",
      "r300",
      "r301"
     ]
    },
    "dei_AmendmentFlag": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "AmendmentFlag",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Amendment Flag",
        "documentation": "Boolean flag that is true when the XBRL content amends previously-filed or accepted submission."
       }
      }
     },
     "auth_ref": []
    },
    "dei_EntityBankruptcyProceedingsReportingCurrent": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityBankruptcyProceedingsReportingCurrent",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Bankruptcy Proceedings, Reporting Current",
        "documentation": "For registrants involved in bankruptcy proceedings during the preceding five years, the value Yes indicates that the registrant has filed all documents and reports required to be filed by Section 12, 13 or 15(d) of the Securities Exchange Act of 1934 subsequent to the distribution of securities under a plan confirmed by a court; the value No indicates the registrant has not.  Registrants not involved in bankruptcy proceedings during the preceding five years should not report this element."
       }
      }
     },
     "auth_ref": [
      "r412"
     ]
    },
    "dei_IcfrAuditorAttestationFlag": {
     "xbrltype": "booleanItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "IcfrAuditorAttestationFlag",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "ICFR Auditor Attestation Flag"
       }
      }
     },
     "auth_ref": [
      "r417",
      "r419",
      "r420"
     ]
    },
    "us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract",
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Cash Flows provided by Financing Activities"
       }
      }
     },
     "auth_ref": []
    },
    "dei_AmendmentDescription": {
     "xbrltype": "stringItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "AmendmentDescription",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Amendment Description",
        "documentation": "Description of changes contained within amended document."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_RevenueRecognitionIncentives": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "RevenueRecognitionIncentives",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Research and Development Incentive Income",
        "documentation": "Disclosure of accounting policy for sales incentives."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Number of vested options",
        "documentation": "Number of options vested."
       }
      }
     },
     "auth_ref": []
    },
    "dei_DocumentFiscalYearFocus": {
     "xbrltype": "gYearItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "DocumentFiscalYearFocus",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Document Fiscal Year Focus",
        "documentation": "This is focus fiscal year of the document report in YYYY format. For a 2006 annual report, which may also provide financial information from prior periods, fiscal 2006 should be given as the fiscal year focus. Example: 2006."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Weighted average grant date fair value, Exercisable",
        "documentation": "Weighted average grant-date fair value of non-vested options outstanding."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_IncomeTaxAuthorityAxis": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeTaxAuthorityAxis",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Income Tax Authority [Axis]",
        "documentation": "Information by tax jurisdiction."
       }
      }
     },
     "auth_ref": [
      "r8"
     ]
    },
    "us-gaap_OperatingLeaseCost": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "OperatingLeaseCost",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Operating lease costs",
        "documentation": "Amount of single lease cost, calculated by allocation of remaining cost of lease over remaining lease term. Includes, but is not limited to, single lease cost, after impairment of right-of-use asset, calculated by amortization of remaining right-of-use asset and accretion of lease liability."
       }
      }
     },
     "auth_ref": [
      "r264",
      "r393"
     ]
    },
    "dei_EntityAddressAddressLine3": {
     "xbrltype": "normalizedStringItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityAddressAddressLine3",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Address, Address Line Three",
        "documentation": "Address Line 3 such as an Office Park"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_PlanNameAxis": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "PlanNameAxis",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Plan Name [Axis]",
        "documentation": "Information by plan name for share-based payment arrangement."
       }
      }
     },
     "auth_ref": [
      "r444",
      "r445",
      "r446",
      "r447",
      "r448",
      "r449",
      "r450",
      "r451",
      "r452",
      "r453",
      "r454",
      "r455",
      "r456",
      "r457",
      "r458",
      "r459",
      "r460",
      "r461",
      "r462",
      "r463",
      "r464",
      "r465",
      "r466",
      "r467",
      "r468",
      "r469"
     ]
    },
    "us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Additional shares of common stock available for issuance",
        "documentation": "Number of additional shares authorized for issuance under share-based payment arrangement."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_AccountingPoliciesAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "AccountingPoliciesAbstract",
     "lang": {
      "en-us": {
       "role": {
        "label": "Accounting Policies [Abstract]"
       }
      }
     },
     "auth_ref": []
    },
    "dei_EntityAddressCityOrTown": {
     "xbrltype": "normalizedStringItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityAddressCityOrTown",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Address, City or Town",
        "documentation": "Name of the City or Town"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_IncomeTaxDisclosureTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeTaxDisclosureTextBlock",
     "presentation": [
      "http://anavex.com/role/IncomeTaxes"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Income Taxes",
        "documentation": "The entire disclosure for income taxes. Disclosures may include net deferred tax liability or asset recognized in an enterprise's statement of financial position, net change during the year in the total valuation allowance, approximate tax effect of each type of temporary difference and carryforward that gives rise to a significant portion of deferred tax liabilities and deferred tax assets, utilization of a tax carryback, and tax uncertainties information."
       }
      }
     },
     "auth_ref": [
      "r111",
      "r214",
      "r219",
      "r220",
      "r226",
      "r231",
      "r235",
      "r236",
      "r237",
      "r309"
     ]
    },
    "us-gaap_ScheduleOfStockOptionsRollForwardTableTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ScheduleOfStockOptionsRollForwardTableTextBlock",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesTables"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Schedule of stock option activity",
        "documentation": "Tabular disclosure of the change in stock options."
       }
      }
     },
     "auth_ref": []
    },
    "dei_EntityAddressStateOrProvince": {
     "xbrltype": "stateOrProvinceItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityAddressStateOrProvince",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Address, State or Province",
        "documentation": "Name of the state or province."
       }
      }
     },
     "auth_ref": []
    },
    "dei_EntityAddressCountry": {
     "xbrltype": "countryCodeItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityAddressCountry",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Address, Country",
        "documentation": "ISO 3166-1 alpha-2 country code."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_AdditionalPaidInCapitalCommonStock": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "AdditionalPaidInCapitalCommonStock",
     "crdr": "credit",
     "calculation": {
      "http://anavex.com/role/BalanceSheets": {
       "parentTag": "us-gaap_StockholdersEquity",
       "weight": 1.0,
       "order": 3.0
      }
     },
     "presentation": [
      "http://anavex.com/role/BalanceSheets"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Additional paid-in capital",
        "documentation": "Value received from shareholders in common stock-related transactions that are in excess of par value or stated value and amounts received from other stock-related transactions. Includes only common stock transactions (excludes preferred stock transactions). May be called contributed capital, capital in excess of par, capital surplus, or paid-in capital."
       }
      }
     },
     "auth_ref": [
      "r54"
     ]
    },
    "us-gaap_PlanNameDomain": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "PlanNameDomain",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Plan name for share-based payment arrangement."
       }
      }
     },
     "auth_ref": [
      "r444",
      "r445",
      "r446",
      "r447",
      "r448",
      "r449",
      "r450",
      "r451",
      "r452",
      "r453",
      "r454",
      "r455",
      "r456",
      "r457",
      "r458",
      "r459",
      "r460",
      "r461",
      "r462",
      "r463",
      "r464",
      "r465",
      "r466",
      "r467",
      "r468",
      "r469"
     ]
    },
    "us-gaap_IncomeTaxPolicyTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeTaxPolicyTextBlock",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "verboseLabel": "Income Taxes",
        "label": "Income Tax, Policy [Policy Text Block]",
        "documentation": "Disclosure of accounting policy for income taxes, which may include its accounting policies for recognizing and measuring deferred tax assets and liabilities and related valuation allowances, recognizing investment tax credits, operating loss carryforwards, tax credit carryforwards, and other carryforwards, methodologies for determining its effective income tax rate and the characterization of interest and penalties in the financial statements."
       }
      }
     },
     "auth_ref": [
      "r101",
      "r216",
      "r217",
      "r220",
      "r221",
      "r225",
      "r227",
      "r303"
     ]
    },
    "dei_EntityAddressPostalZipCode": {
     "xbrltype": "normalizedStringItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "EntityAddressPostalZipCode",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Entity Address, Postal Zip Code",
        "documentation": "Code for the postal or zip code"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_SharesOutstanding": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SharesOutstanding",
     "presentation": [
      "http://anavex.com/role/StatementsOfChangesInStockholdersEquity"
     ],
     "lang": {
      "en-us": {
       "role": {
        "periodStartLabel": "Balance at beginning, shares",
        "periodEndLabel": "Balance at ending, shares",
        "label": "Shares, Outstanding",
        "documentation": "Number of shares issued which are neither cancelled nor held in the treasury."
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_AwardTypeAxis": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "AwardTypeAxis",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Award Type [Axis]",
        "documentation": "Information by type of award under share-based payment arrangement."
       }
      }
     },
     "auth_ref": [
      "r179",
      "r180",
      "r181",
      "r182",
      "r183",
      "r184",
      "r185",
      "r186",
      "r187",
      "r188",
      "r189",
      "r190",
      "r191",
      "r192",
      "r193",
      "r194",
      "r195",
      "r196",
      "r197",
      "r198",
      "r199",
      "r200",
      "r201",
      "r202",
      "r203",
      "r204"
     ]
    },
    "us-gaap_ClassOfStockDomain": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ClassOfStockDomain",
     "presentation": [
      "http://anavex.com/role/EquityOfferingsDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Share of stock differentiated by the voting rights the holder receives. Examples include, but are not limited to, common stock, redeemable preferred stock, nonredeemable preferred stock, and convertible stock."
       }
      }
     },
     "auth_ref": [
      "r90",
      "r95",
      "r96",
      "r97",
      "r109",
      "r127",
      "r128",
      "r130",
      "r132",
      "r136",
      "r137",
      "r151",
      "r160",
      "r162",
      "r163",
      "r164",
      "r167",
      "r168",
      "r169",
      "r170",
      "r171",
      "r172",
      "r173",
      "r252",
      "r304",
      "r305",
      "r306",
      "r307",
      "r310",
      "r311",
      "r312",
      "r313",
      "r314",
      "r315",
      "r316",
      "r317",
      "r318",
      "r319",
      "r320",
      "r321",
      "r332",
      "r354",
      "r373",
      "r381",
      "r382",
      "r383",
      "r384",
      "r385",
      "r427",
      "r432",
      "r438"
     ]
    },
    "us-gaap_PreferredStockSharesAuthorized": {
     "xbrltype": "sharesItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "PreferredStockSharesAuthorized",
     "presentation": [
      "http://anavex.com/role/BalanceSheetsParenthetical"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Preferred stock, authorized",
        "documentation": "The maximum number of nonredeemable preferred shares (or preferred stock redeemable solely at the option of the issuer) permitted to be issued by an entity's charter and bylaws."
       }
      }
     },
     "auth_ref": [
      "r52",
      "r332"
     ]
    },
    "dei_CountryRegion": {
     "xbrltype": "normalizedStringItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "CountryRegion",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Country Region",
        "documentation": "Region code of country"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ProceedsFromStockOptionsExercised": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ProceedsFromStockOptionsExercised",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/StatementsOfCashFlows": {
       "parentTag": "us-gaap_NetCashProvidedByUsedInFinancingActivities",
       "weight": 1.0,
       "order": 4.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Proceeds from exercise of stock options",
        "documentation": "Amount of cash inflow from exercise of option under share-based payment arrangement."
       }
      }
     },
     "auth_ref": [
      "r2",
      "r12"
     ]
    },
    "us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeTaxReconciliationChangeInEnactedTaxRate",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Effect of change in statutory tax rates",
        "documentation": "Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations, attributable to increase (decrease) in the income tax rates."
       }
      }
     },
     "auth_ref": [
      "r215",
      "r218"
     ]
    },
    "dei_CityAreaCode": {
     "xbrltype": "normalizedStringItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "CityAreaCode",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "City Area Code",
        "documentation": "Area code of city"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_PreferredStockParOrStatedValuePerShare": {
     "xbrltype": "perShareItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "PreferredStockParOrStatedValuePerShare",
     "presentation": [
      "http://anavex.com/role/BalanceSheetsParenthetical"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Preferred stock, par value",
        "documentation": "Face amount or stated value per share of preferred stock nonredeemable or redeemable solely at the option of the issuer."
       }
      }
     },
     "auth_ref": [
      "r52",
      "r169"
     ]
    },
    "us-gaap_SegmentReportingPolicyPolicyTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SegmentReportingPolicyPolicyTextBlock",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Segment and Geographic Reporting",
        "documentation": "Disclosure of accounting policy for segment reporting."
       }
      }
     },
     "auth_ref": [
      "r139",
      "r140",
      "r141",
      "r142",
      "r143",
      "r144",
      "r150",
      "r392"
     ]
    },
    "us-gaap_IncomeStatementLocationAxis": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeStatementLocationAxis",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails5"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Income Statement Location [Axis]",
        "documentation": "Information by location in the income statement."
       }
      }
     },
     "auth_ref": [
      "r154",
      "r155",
      "r357"
     ]
    },
    "us-gaap_IncomeStatementAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeStatementAbstract",
     "lang": {
      "en-us": {
       "role": {
        "label": "Income Statement [Abstract]"
       }
      }
     },
     "auth_ref": []
    },
    "us-gaap_ShareBasedCompensationForfeituresPolicyTextBlock": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ShareBasedCompensationForfeituresPolicyTextBlock",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Stock-based Compensation",
        "documentation": "Disclosure of accounting policy election for determining cost for share-based payment arrangement by either estimating forfeiture expected to occur or by recognizing effect of forfeiture upon occurrence."
       }
      }
     },
     "auth_ref": [
      "r176",
      "r178",
      "r206"
     ]
    },
    "us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeTaxReconciliationForeignIncomeTaxRateDifferential",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Foreign income taxed at other rates",
        "documentation": "Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to foreign income tax expense (benefit)."
       }
      }
     },
     "auth_ref": [
      "r471"
     ]
    },
    "us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetails2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Income tax benefit at statutory federal rate",
        "documentation": "The amount of income tax expense or benefit for the period computed by applying the domestic federal statutory tax rates to pretax income from continuing operations."
       }
      }
     },
     "auth_ref": [
      "r218"
     ]
    },
    "us-gaap_IncomeStatementLocationDomain": {
     "xbrltype": "domainItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeStatementLocationDomain",
     "presentation": [
      "http://anavex.com/role/CommitmentsAndContingenciesDetails5"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Location in the income statement."
       }
      }
     },
     "auth_ref": [
      "r155",
      "r357"
     ]
    },
    "dei_Security12bTitle": {
     "xbrltype": "securityTitleItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "Security12bTitle",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Title of 12(b) Security",
        "documentation": "Title of a 12(b) registered security."
       }
      }
     },
     "auth_ref": [
      "r407"
     ]
    },
    "us-gaap_UseOfEstimates": {
     "xbrltype": "textBlockItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "UseOfEstimates",
     "presentation": [
      "http://anavex.com/role/SummaryOfSignificantAccountingPoliciesPolicies"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Use of Estimates",
        "documentation": "Disclosure of accounting policy for the use of estimates in the preparation of financial statements in conformity with generally accepted accounting principles."
       }
      }
     },
     "auth_ref": [
      "r25",
      "r26",
      "r27",
      "r85",
      "r86",
      "r87",
      "r88"
     ]
    },
    "dei_NoTradingSymbolFlag": {
     "xbrltype": "trueItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "NoTradingSymbolFlag",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "No Trading Symbol Flag",
        "documentation": "Boolean flag that is true only for a security having no trading symbol."
       }
      }
     },
     "auth_ref": []
    },
    "dei_AuditorLocation": {
     "xbrltype": "internationalNameItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "AuditorLocation",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Auditor Location"
       }
      }
     },
     "auth_ref": [
      "r417",
      "r419",
      "r420"
     ]
    },
    "us-gaap_ProceedsFromWarrantExercises": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "ProceedsFromWarrantExercises",
     "crdr": "debit",
     "calculation": {
      "http://anavex.com/role/StatementsOfCashFlows": {
       "parentTag": "us-gaap_NetCashProvidedByUsedInFinancingActivities",
       "weight": 1.0,
       "order": 3.0
      }
     },
     "presentation": [
      "http://anavex.com/role/StatementsOfCashFlows"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Proceeds from exercise of warrants",
        "documentation": "The cash inflow associated with the amount received from holders exercising their stock warrants."
       }
      }
     },
     "auth_ref": [
      "r431"
     ]
    },
    "dei_TradingSymbol": {
     "xbrltype": "tradingSymbolItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "TradingSymbol",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Trading Symbol",
        "documentation": "Trading symbol of an instrument as listed on an exchange."
       }
      }
     },
     "auth_ref": []
    },
    "dei_AuditorName": {
     "xbrltype": "internationalNameItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "AuditorName",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Auditor Name"
       }
      }
     },
     "auth_ref": [
      "r417",
      "r419",
      "r420"
     ]
    },
    "us-gaap_IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment": {
     "xbrltype": "monetaryItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopment",
     "crdr": "debit",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Research and Development tax credits",
        "documentation": "Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to nondeductible research and development expense."
       }
      }
     },
     "auth_ref": [
      "r471"
     ]
    },
    "dei_SecurityExchangeName": {
     "xbrltype": "edgarExchangeCodeItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "SecurityExchangeName",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Security Exchange Name",
        "documentation": "Name of the Exchange on which a security is registered."
       }
      }
     },
     "auth_ref": [
      "r410"
     ]
    },
    "dei_AuditorFirmId": {
     "xbrltype": "nonemptySequenceNumberItemType",
     "nsuri": "http://xbrl.sec.gov/dei/2023",
     "localname": "AuditorFirmId",
     "presentation": [
      "http://anavex.com/role/Cover"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Auditor Firm ID",
        "documentation": "PCAOB issued Audit Firm Identifier"
       }
      }
     },
     "auth_ref": [
      "r417",
      "r419",
      "r420"
     ]
    },
    "us-gaap_SubsequentEventsAbstract": {
     "xbrltype": "stringItemType",
     "nsuri": "http://fasb.org/us-gaap/2023",
     "localname": "SubsequentEventsAbstract",
     "lang": {
      "en-us": {
       "role": {
        "label": "Subsequent Events [Abstract]"
       }
      }
     },
     "auth_ref": []
    },
    "currency_AUD": {
     "xbrltype": "domainItemType",
     "nsuri": "http://xbrl.sec.gov/currency/2023",
     "localname": "AUD",
     "presentation": [
      "http://anavex.com/role/IncomeTaxesDetailsNarrative",
      "http://anavex.com/role/OtherIncomeDetailsNarrative"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Australia, Dollars"
       }
      }
     },
     "auth_ref": []
    }
   }
  }
 },
 "std_ref": {
  "r0": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Section": "25",
   "Paragraph": "1",
   "SubTopic": "20",
   "Topic": "940",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481913/940-20-25-1"
  },
  "r1": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "1",
   "SubTopic": "230",
   "Topic": "830",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481877/830-230-45-1"
  },
  "r2": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "14",
   "Subparagraph": "(a)",
   "SubTopic": "10",
   "Topic": "230",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482740/230-10-45-14"
  },
  "r3": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "25",
   "Subparagraph": "(g)",
   "SubTopic": "10",
   "Topic": "230",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482740/230-10-45-25"
  },
  "r4": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "28",
   "Subparagraph": "(a)",
   "SubTopic": "10",
   "Topic": "230",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482740/230-10-45-28"
  },
  "r5": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "28",
   "Subparagraph": "(b)",
   "SubTopic": "10",
   "Topic": "230",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482740/230-10-45-28"
  },
  "r6": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "SubTopic": "10",
   "Topic": "825",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482907/825-10-50-1"
  },
  "r7": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "SubTopic": "20",
   "Topic": "715",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480506/715-20-50-1"
  },
  "r8": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "15",
   "Subparagraph": "(e)",
   "SubTopic": "10",
   "Topic": "740",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-15"
  },
  "r9": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "SubTopic": "10",
   "Topic": "505",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481112/505-10-50-2"
  },
  "r10": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(d)",
   "SubTopic": "10",
   "Topic": "718",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r11": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(e)",
   "SubTopic": "10",
   "Topic": "718",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r12": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2A",
   "Subparagraph": "(a)",
   "SubTopic": "10",
   "Topic": "718",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2A"
  },
  "r13": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Section": "60",
   "Paragraph": "1",
   "SubTopic": "10",
   "Topic": "820",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482053/820-10-60-1"
  },
  "r14": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "210",
   "SubTopic": "10",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02.19(a))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r15": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "210",
   "SubTopic": "10",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02.19-26)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r16": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "210",
   "SubTopic": "10",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02.20)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r17": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "210",
   "SubTopic": "10",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02.25)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r18": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "210",
   "SubTopic": "10",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02.29)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r19": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "210",
   "SubTopic": "10",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02.29-31)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r20": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "230",
   "SubTopic": "10",
   "Section": "45",
   "Paragraph": "15",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482740/230-10-45-15"
  },
  "r21": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "230",
   "SubTopic": "10",
   "Section": "45",
   "Paragraph": "4",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482740/230-10-45-4"
  },
  "r22": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "230",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482913/230-10-50-1"
  },
  "r23": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "260",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "1",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482662/260-10-50-1"
  },
  "r24": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "260",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "2",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482662/260-10-50-2"
  },
  "r25": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "275",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "4",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482861/275-10-50-4"
  },
  "r26": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "275",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "8",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482861/275-10-50-8"
  },
  "r27": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "275",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "9",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482861/275-10-50-9"
  },
  "r28": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "715",
   "SubTopic": "20",
   "Section": "50",
   "Paragraph": "2",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480506/715-20-50-2"
  },
  "r29": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "715",
   "SubTopic": "20",
   "Section": "50",
   "Paragraph": "3",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480506/715-20-50-3"
  },
  "r30": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "715",
   "SubTopic": "20",
   "Section": "50",
   "Paragraph": "4",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480506/715-20-50-4"
  },
  "r31": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "715",
   "SubTopic": "20",
   "Section": "55",
   "Paragraph": "17",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480482/715-20-55-17"
  },
  "r32": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "715",
   "SubTopic": "70",
   "Section": "50",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480794/715-70-50-1"
  },
  "r33": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "718",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "2",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r34": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "718",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r35": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "718",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(f)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r36": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "718",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(g)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r37": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "718",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(h)(1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r38": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "718",
   "SubTopic": "20",
   "Section": "55",
   "Paragraph": "12",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481089/718-20-55-12"
  },
  "r39": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "718",
   "SubTopic": "20",
   "Section": "55",
   "Paragraph": "13",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481089/718-20-55-13"
  },
  "r40": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "740",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "3",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-3"
  },
  "r41": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "740",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "3",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-3"
  },
  "r42": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "740",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "8",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-8"
  },
  "r43": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "810",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481203/810-10-50-1"
  },
  "r44": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "815",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "4A",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480434/815-10-50-4A"
  },
  "r45": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "815",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "4B",
   "Subparagraph": "(c)(1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480434/815-10-50-4B"
  },
  "r46": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "815",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "4C",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480434/815-10-50-4C"
  },
  "r47": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "815",
   "SubTopic": "10",
   "Section": "50",
   "Paragraph": "4D",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480434/815-10-50-4D"
  },
  "r48": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "942",
   "SubTopic": "210",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.9-03.10)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479853/942-210-S99-1"
  },
  "r49": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "942",
   "SubTopic": "210",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.9-03.17)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479853/942-210-S99-1"
  },
  "r50": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Name": "Accounting Standards Codification",
   "Topic": "985",
   "SubTopic": "20",
   "Section": "50",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481283/985-20-50-1"
  },
  "r51": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "205",
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//205/tableOfContent"
  },
  "r52": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02(28))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r53": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02(29))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r54": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02(30)(a)(1))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r55": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02(30)(a)(3))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r56": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02(30))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r57": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02(31))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r58": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02(32))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r59": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "210",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "3",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483466/210-20-50-3"
  },
  "r60": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "210",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "4",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483466/210-20-50-4"
  },
  "r61": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "220",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "2",
   "Subparagraph": "(SX 210.5-03(10))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483621/220-10-S99-2"
  },
  "r62": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "220",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "2",
   "Subparagraph": "(SX 210.5-03(20))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483621/220-10-S99-2"
  },
  "r63": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "220",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "2",
   "Subparagraph": "(SX 210.5-03(4))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483621/220-10-S99-2"
  },
  "r64": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "220",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "2",
   "Subparagraph": "(SX 210.5-03.4)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483621/220-10-S99-2"
  },
  "r65": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "220",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "2",
   "Subparagraph": "(SX 210.5-03.7)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483621/220-10-S99-2"
  },
  "r66": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "230",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "24",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482740/230-10-45-24"
  },
  "r67": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "230",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "25",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482740/230-10-45-25"
  },
  "r68": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "230",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "28",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482740/230-10-45-28"
  },
  "r69": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "235",
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//235/tableOfContent"
  },
  "r70": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "310",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "2",
   "Subparagraph": "(SAB Topic 4.E)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480418/310-10-S99-2"
  },
  "r71": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "440",
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//440/tableOfContent"
  },
  "r72": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "505",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.3-04)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480008/505-10-S99-1"
  },
  "r73": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "718",
   "SubTopic": "10",
   "Subparagraph": "(e)(1)",
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Section": "50",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r74": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "718",
   "SubTopic": "10",
   "Subparagraph": "(e)(2)",
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Section": "50",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r75": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Paragraph": "12",
   "Section": "50",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-12"
  },
  "r76": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Section": "50",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-2"
  },
  "r77": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SAB Topic 6.I.7)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479360/740-10-S99-1"
  },
  "r78": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "810",
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//810/tableOfContent"
  },
  "r79": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "942",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.9-03(11))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479853/942-210-S99-1"
  },
  "r80": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "942",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.9-03(23))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479853/942-210-S99-1"
  },
  "r81": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "942",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.9-04(15))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483589/942-220-S99-1"
  },
  "r82": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "942",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.9-04(22))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483589/942-220-S99-1"
  },
  "r83": {
   "role": "http://fasb.org/us-gaap/role/ref/legacyRef",
   "Topic": "942",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.9-04.10)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483589/942-220-S99-1"
  },
  "r84": {
   "role": "http://fasb.org/us-gaap/role/ref/otherTransitionRef",
   "Topic": "840",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "25",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481178/840-20-25-1"
  },
  "r85": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Subparagraph": "(b)",
   "SubTopic": "10",
   "Topic": "275",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482861/275-10-50-1"
  },
  "r86": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Subparagraph": "(c)",
   "SubTopic": "10",
   "Topic": "275",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482861/275-10-50-1"
  },
  "r87": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "11",
   "SubTopic": "10",
   "Topic": "275",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482861/275-10-50-11"
  },
  "r88": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "12",
   "SubTopic": "10",
   "Topic": "275",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482861/275-10-50-12"
  },
  "r89": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "9",
   "Subparagraph": "(b)",
   "SubTopic": "10",
   "Topic": "740",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-9"
  },
  "r90": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Name": "Regulation S-K (SK)",
   "Number": "229",
   "Section": "1402",
   "Paragraph": "(a)",
   "Publisher": "SEC"
  },
  "r91": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "105",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "6",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479343/105-10-65-6"
  },
  "r92": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "205",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "7",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483499/205-20-50-7"
  },
  "r93": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02(1))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r94": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02(18))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r95": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02(27)(b))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r96": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02(28))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r97": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02(29))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r98": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02(3)(a)(4))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r99": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "220",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "1A",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482790/220-10-45-1A"
  },
  "r100": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "220",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "1B",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482790/220-10-45-1B"
  },
  "r101": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "220",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482765/220-10-50-1"
  },
  "r102": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "220",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "4",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482765/220-10-50-4"
  },
  "r103": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "220",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "5",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482765/220-10-50-5"
  },
  "r104": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "220",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "6",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482765/220-10-50-6"
  },
  "r105": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "220",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "2",
   "Subparagraph": "(SX 210.5-03(25))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483621/220-10-S99-2"
  },
  "r106": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "230",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "24",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482740/230-10-45-24"
  },
  "r107": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "230",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "8",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482913/230-10-50-8"
  },
  "r108": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "235",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483426/235-10-50-1"
  },
  "r109": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "235",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.4-08(g)(1)(ii))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480678/235-10-S99-1"
  },
  "r110": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "235",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.4-08(h)(1))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480678/235-10-S99-1"
  },
  "r111": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "235",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.4-08(h)(2))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480678/235-10-S99-1"
  },
  "r112": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "23",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483421/250-10-45-23"
  },
  "r113": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "24",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483421/250-10-45-24"
  },
  "r114": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "5",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483421/250-10-45-5"
  },
  "r115": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Subparagraph": "(b)(2)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483443/250-10-50-1"
  },
  "r116": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Subparagraph": "(b)(3)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483443/250-10-50-1"
  },
  "r117": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "11",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483443/250-10-50-11"
  },
  "r118": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "11",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483443/250-10-50-11"
  },
  "r119": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "3",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483443/250-10-50-3"
  },
  "r120": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "4",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483443/250-10-50-4"
  },
  "r121": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "7",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483443/250-10-50-7"
  },
  "r122": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "7",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483443/250-10-50-7"
  },
  "r123": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "8",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483443/250-10-50-8"
  },
  "r124": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "9",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483443/250-10-50-9"
  },
  "r125": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "260",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "10",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482689/260-10-45-10"
  },
  "r126": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "260",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "16",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482689/260-10-45-16"
  },
  "r127": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "260",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "2",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482689/260-10-45-2"
  },
  "r128": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "260",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "3",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482689/260-10-45-3"
  },
  "r129": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "260",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "60B",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482689/260-10-45-60B"
  },
  "r130": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "260",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "60B",
   "Subparagraph": "(d)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482689/260-10-45-60B"
  },
  "r131": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "260",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "7",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482689/260-10-45-7"
  },
  "r132": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "260",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482662/260-10-50-1"
  },
  "r133": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "260",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482662/260-10-50-1"
  },
  "r134": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "260",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "55",
   "Paragraph": "15",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482635/260-10-55-15"
  },
  "r135": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "272",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483014/272-10-45-1"
  },
  "r136": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "272",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482987/272-10-50-1"
  },
  "r137": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "272",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "3",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482987/272-10-50-3"
  },
  "r138": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "22",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482810/280-10-50-22"
  },
  "r139": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "29",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482810/280-10-50-29"
  },
  "r140": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "29",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482810/280-10-50-29"
  },
  "r141": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "29",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482810/280-10-50-29"
  },
  "r142": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "29",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482810/280-10-50-29"
  },
  "r143": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "29",
   "Subparagraph": "(d)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482810/280-10-50-29"
  },
  "r144": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "29",
   "Subparagraph": "(e)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482810/280-10-50-29"
  },
  "r145": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "30",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482810/280-10-50-30"
  },
  "r146": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "30",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482810/280-10-50-30"
  },
  "r147": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "32",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482810/280-10-50-32"
  },
  "r148": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "32",
   "Subparagraph": "(d)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482810/280-10-50-32"
  },
  "r149": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "32",
   "Subparagraph": "(f)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482810/280-10-50-32"
  },
  "r150": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "41",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482810/280-10-50-41"
  },
  "r151": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "323",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "3",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481687/323-10-50-3"
  },
  "r152": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "326",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "4",
   "Subparagraph": "(d)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479654/326-10-65-4"
  },
  "r153": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "326",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "5",
   "Subparagraph": "(c)(2)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479654/326-10-65-5"
  },
  "r154": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "360",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "3",
   "Subparagraph": "(d)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482099/360-10-50-3"
  },
  "r155": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "420",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482017/420-10-50-1"
  },
  "r156": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "450",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483076/450-20-50-1"
  },
  "r157": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "450",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "4",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483076/450-20-50-4"
  },
  "r158": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "450",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "9",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483076/450-20-50-9"
  },
  "r159": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "460",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "3",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482425/460-10-50-3"
  },
  "r160": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "470",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1A",
   "Subparagraph": "(SX 210.13-01(a)(4)(i))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480097/470-10-S99-1A"
  },
  "r161": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "470",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1A",
   "Subparagraph": "(SX 210.13-01(a)(4)(iii)(A))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480097/470-10-S99-1A"
  },
  "r162": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "470",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1A",
   "Subparagraph": "(SX 210.13-01(a)(4)(iv))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480097/470-10-S99-1A"
  },
  "r163": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "470",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1A",
   "Subparagraph": "(SX 210.13-01(a)(5))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480097/470-10-S99-1A"
  },
  "r164": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "470",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1B",
   "Subparagraph": "(SX 210.13-02(a)(4)(i))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480097/470-10-S99-1B"
  },
  "r165": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "470",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1B",
   "Subparagraph": "(SX 210.13-02(a)(4)(iii)(A))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480097/470-10-S99-1B"
  },
  "r166": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "470",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1B",
   "Subparagraph": "(SX 210.13-02(a)(4)(iii)(B))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480097/470-10-S99-1B"
  },
  "r167": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "470",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1B",
   "Subparagraph": "(SX 210.13-02(a)(4)(iv))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480097/470-10-S99-1B"
  },
  "r168": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "470",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1B",
   "Subparagraph": "(SX 210.13-02(a)(5))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480097/470-10-S99-1B"
  },
  "r169": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "505",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "13",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481112/505-10-50-13"
  },
  "r170": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "505",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "13",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481112/505-10-50-13"
  },
  "r171": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "505",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "13",
   "Subparagraph": "(h)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481112/505-10-50-13"
  },
  "r172": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "505",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "14",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481112/505-10-50-14"
  },
  "r173": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "505",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481112/505-10-50-2"
  },
  "r174": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "505",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.3-04)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480008/505-10-S99-1"
  },
  "r175": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "715",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Subparagraph": "(n)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480506/715-20-50-1"
  },
  "r176": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "35",
   "Paragraph": "1D",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480483/718-10-35-1D"
  },
  "r177": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "35",
   "Paragraph": "2",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480483/718-10-35-2"
  },
  "r178": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "35",
   "Paragraph": "3",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480483/718-10-35-3"
  },
  "r179": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(a)(1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r180": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(a)(2)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r181": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(a)(3)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r182": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(i)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r183": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(ii)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r184": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(iii)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r185": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(iv)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r186": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(iv)(01)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r187": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(iv)(02)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r188": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(iv)(03)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r189": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(iv)(04)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r190": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(2)(i)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r191": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(2)(ii)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r192": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(2)(iii)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r193": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(2)(iii)(01)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r194": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(2)(iii)(02)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r195": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(2)(iii)(03)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r196": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(d)(1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r197": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(d)(2)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r198": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(e)(1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r199": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(e)(2)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r200": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(f)(2)(i)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r201": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(f)(2)(ii)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r202": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(f)(2)(iii)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r203": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(f)(2)(iv)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r204": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(f)(2)(v)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r205": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(h)(1)(i)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r206": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(m)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r207": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "15",
   "Subparagraph": "(e)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480336/718-10-65-15"
  },
  "r208": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "15",
   "Subparagraph": "(f)(1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480336/718-10-65-15"
  },
  "r209": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "15",
   "Subparagraph": "(f)(2)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480336/718-10-65-15"
  },
  "r210": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SAB Topic 14.F)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479830/718-10-S99-1"
  },
  "r211": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "730",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "05",
   "Paragraph": "1",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483044/730-10-05-1"
  },
  "r212": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "730",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482916/730-10-50-1"
  },
  "r213": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "730",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483041/730-20-50-1"
  },
  "r214": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//740/tableOfContent"
  },
  "r215": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "15",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482525/740-10-45-15"
  },
  "r216": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "25",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482525/740-10-45-25"
  },
  "r217": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "28",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482525/740-10-45-28"
  },
  "r218": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "12",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-12"
  },
  "r219": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "14",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-14"
  },
  "r220": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "17",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-17"
  },
  "r221": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "19",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-19"
  },
  "r222": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-2"
  },
  "r223": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-2"
  },
  "r224": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-2"
  },
  "r225": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "20",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-20"
  },
  "r226": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "21",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-21"
  },
  "r227": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "9",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-9"
  },
  "r228": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "9",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-9"
  },
  "r229": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "8",
   "Subparagraph": "(d)(2)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482615/740-10-65-8"
  },
  "r230": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "8",
   "Subparagraph": "(d)(3)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482615/740-10-65-8"
  },
  "r231": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SAB TOPIC 6.I.5.Q1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479360/740-10-S99-1"
  },
  "r232": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SAB Topic 6.I.Fact.1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479360/740-10-S99-1"
  },
  "r233": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SAB Topic 6.I.Fact.2)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479360/740-10-S99-1"
  },
  "r234": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SAB Topic 6.I.Fact.3)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479360/740-10-S99-1"
  },
  "r235": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "2",
   "Subparagraph": "(SAB Topic 11.C)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479360/740-10-S99-2"
  },
  "r236": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "270",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482526/740-270-50-1"
  },
  "r237": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "740",
   "SubTopic": "30",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482603/740-30-50-2"
  },
  "r238": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "808",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Subparagraph": "(d)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479402/808-10-50-1"
  },
  "r239": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "810",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "25",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481231/810-10-45-25"
  },
  "r240": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "810",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "25",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481231/810-10-45-25"
  },
  "r241": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "810",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "3",
   "Subparagraph": "(bb)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481203/810-10-50-3"
  },
  "r242": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "810",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "3",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481203/810-10-50-3"
  },
  "r243": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "815",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "6",
   "Subparagraph": "(e)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480528/815-20-65-6"
  },
  "r244": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "815",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "6",
   "Subparagraph": "(h)(1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480528/815-20-65-6"
  },
  "r245": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "815",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "6",
   "Subparagraph": "(h)(1)(i)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480528/815-20-65-6"
  },
  "r246": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "815",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "6",
   "Subparagraph": "(h)(1)(iii)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480528/815-20-65-6"
  },
  "r247": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "815",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "6",
   "Subparagraph": "(h)(1)(iv)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480528/815-20-65-6"
  },
  "r248": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "815",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "6",
   "Subparagraph": "(i)(3)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480528/815-20-65-6"
  },
  "r249": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "815",
   "SubTopic": "40",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "1",
   "Subparagraph": "(e)(3)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480175/815-40-65-1"
  },
  "r250": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "815",
   "SubTopic": "40",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "1",
   "Subparagraph": "(e)(4)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480175/815-40-65-1"
  },
  "r251": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "815",
   "SubTopic": "40",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "1",
   "Subparagraph": "(f)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480175/815-40-65-1"
  },
  "r252": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "825",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "28",
   "Subparagraph": "(f)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482907/825-10-50-28"
  },
  "r253": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "830",
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//830/tableOfContent"
  },
  "r254": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "830",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "17",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481839/830-10-45-17"
  },
  "r255": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "830",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "35",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482014/830-20-35-1"
  },
  "r256": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "830",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481956/830-20-45-1"
  },
  "r257": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "830",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481926/830-20-50-1"
  },
  "r258": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "830",
   "SubTopic": "30",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "17",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481694/830-30-45-17"
  },
  "r259": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "830",
   "SubTopic": "30",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "20",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481694/830-30-45-20"
  },
  "r260": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "830",
   "SubTopic": "30",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "20",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481694/830-30-45-20"
  },
  "r261": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "830",
   "SubTopic": "30",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "20",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481694/830-30-45-20"
  },
  "r262": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "830",
   "SubTopic": "30",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "20",
   "Subparagraph": "(d)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481694/830-30-45-20"
  },
  "r263": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "830",
   "SubTopic": "30",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481674/830-30-50-1"
  },
  "r264": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "842",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "4",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147478964/842-20-50-4"
  },
  "r265": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "842",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "4",
   "Subparagraph": "(g)(3)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147478964/842-20-50-4"
  },
  "r266": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "848",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "2",
   "Subparagraph": "(a)(3)(iii)(03)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483550/848-10-65-2"
  },
  "r267": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "850",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483326/850-10-50-1"
  },
  "r268": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "850",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Subparagraph": "(d)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483326/850-10-50-1"
  },
  "r269": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "855",
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//855/tableOfContent"
  },
  "r270": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "855",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483399/855-10-50-2"
  },
  "r271": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "924",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SAB Topic 11.L)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479941/924-10-S99-1"
  },
  "r272": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "932",
   "SubTopic": "235",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "15",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482274/932-235-50-15"
  },
  "r273": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "932",
   "SubTopic": "235",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "15",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482274/932-235-50-15"
  },
  "r274": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "932",
   "SubTopic": "235",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "20",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482274/932-235-50-20"
  },
  "r275": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "932",
   "SubTopic": "235",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "20",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482274/932-235-50-20"
  },
  "r276": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "932",
   "SubTopic": "235",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "28",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482274/932-235-50-28"
  },
  "r277": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "932",
   "SubTopic": "235",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "28",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482274/932-235-50-28"
  },
  "r278": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "932",
   "SubTopic": "235",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "33",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482274/932-235-50-33"
  },
  "r279": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "932",
   "SubTopic": "235",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "33",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482274/932-235-50-33"
  },
  "r280": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "932",
   "SubTopic": "235",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "35A",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482274/932-235-50-35A"
  },
  "r281": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "932",
   "SubTopic": "235",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "35A",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482274/932-235-50-35A"
  },
  "r282": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "932",
   "SubTopic": "235",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "8",
   "Subparagraph": "(c)(1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482274/932-235-50-8"
  },
  "r283": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "932",
   "SubTopic": "235",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "8",
   "Subparagraph": "(c)(2)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482274/932-235-50-8"
  },
  "r284": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "942",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.9-04(27))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483589/942-220-S99-1"
  },
  "r285": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "942",
   "SubTopic": "235",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.9-05(b)(2))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479557/942-235-S99-1"
  },
  "r286": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "944",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.7-03(a)(12))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479440/944-210-S99-1"
  },
  "r287": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "944",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.7-03(a)(19))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479440/944-210-S99-1"
  },
  "r288": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "944",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.7-03(a)(21))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479440/944-210-S99-1"
  },
  "r289": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "944",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.7-03(a)(22))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479440/944-210-S99-1"
  },
  "r290": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "944",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.7-03(a)(23)(a)(4))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479440/944-210-S99-1"
  },
  "r291": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "944",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.7-03(a)(25))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479440/944-210-S99-1"
  },
  "r292": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "944",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.7-04(11))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483586/944-220-S99-1"
  },
  "r293": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "944",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.7-04(18))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483586/944-220-S99-1"
  },
  "r294": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "944",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.7-04(23))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483586/944-220-S99-1"
  },
  "r295": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "944",
   "SubTopic": "40",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "2",
   "Subparagraph": "(e)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480016/944-40-65-2"
  },
  "r296": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "944",
   "SubTopic": "40",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "2",
   "Subparagraph": "(f)(1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480016/944-40-65-2"
  },
  "r297": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "944",
   "SubTopic": "40",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "2",
   "Subparagraph": "(f)(2)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480016/944-40-65-2"
  },
  "r298": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "944",
   "SubTopic": "40",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "2",
   "Subparagraph": "(g)(2)(i)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480016/944-40-65-2"
  },
  "r299": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "944",
   "SubTopic": "40",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "2",
   "Subparagraph": "(h)(2)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480016/944-40-65-2"
  },
  "r300": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480424/946-10-50-1"
  },
  "r301": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480424/946-10-50-2"
  },
  "r302": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "3",
   "Subparagraph": "(SX 210.6-03(d))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479886/946-10-S99-3"
  },
  "r303": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "3",
   "Subparagraph": "(SX 210.6-03(h)(1))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479886/946-10-S99-3"
  },
  "r304": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "3",
   "Subparagraph": "(SX 210.6-03(i)(1))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479886/946-10-S99-3"
  },
  "r305": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "3",
   "Subparagraph": "(SX 210.6-03(i)(2)(i))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479886/946-10-S99-3"
  },
  "r306": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "3",
   "Subparagraph": "(SX 210.6-03(i)(2)(ii))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479886/946-10-S99-3"
  },
  "r307": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "3",
   "Subparagraph": "(SX 210.6-03(i)(2))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479886/946-10-S99-3"
  },
  "r308": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "11",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480990/946-20-50-11"
  },
  "r309": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "13",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480990/946-20-50-13"
  },
  "r310": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "205",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "4",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480767/946-205-45-4"
  },
  "r311": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "205",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480737/946-205-50-2"
  },
  "r312": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "205",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "27",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480737/946-205-50-27"
  },
  "r313": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "205",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "7",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480737/946-205-50-7"
  },
  "r314": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "205",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "7",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480737/946-205-50-7"
  },
  "r315": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "205",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "7",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480737/946-205-50-7"
  },
  "r316": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "205",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "7",
   "Subparagraph": "(d)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480737/946-205-50-7"
  },
  "r317": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "205",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "7",
   "Subparagraph": "(e)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480737/946-205-50-7"
  },
  "r318": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "205",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "7",
   "Subparagraph": "(f)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480737/946-205-50-7"
  },
  "r319": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "205",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "7",
   "Subparagraph": "(g)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480737/946-205-50-7"
  },
  "r320": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "205",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "7",
   "Subparagraph": "(h)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480737/946-205-50-7"
  },
  "r321": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "4",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480555/946-210-45-4"
  },
  "r322": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "6",
   "Subparagraph": "(a)(4)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480524/946-210-50-6"
  },
  "r323": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "6",
   "Subparagraph": "(f)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480524/946-210-50-6"
  },
  "r324": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(1))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r325": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(12)(b)(1))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r326": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(12)(b)(2))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r327": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(12)(b)(3))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r328": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(13)(a)(2))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r329": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(13)(a)(3))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r330": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(14))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r331": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(15))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r332": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(16)(a))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r333": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(17))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r334": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(19))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r335": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(2)(a))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r336": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(2)(b))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r337": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(3)(a))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r338": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(3)(b))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r339": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(3)(c))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r340": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(5)(a)(5))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r341": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(6)(b))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r342": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(6)(c))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r343": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(6)(d))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r344": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(6)(e))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r345": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(8))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r346": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(9)(b))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r347": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(9)(c))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r348": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(9)(d))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r349": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-04(9)(e))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-1"
  },
  "r350": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "2",
   "Subparagraph": "(SX 210.6-05(2))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-2"
  },
  "r351": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "2",
   "Subparagraph": "(SX 210.6-05(4))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479617/946-210-S99-2"
  },
  "r352": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "3",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483581/946-220-45-3"
  },
  "r353": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "7",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483581/946-220-45-7"
  },
  "r354": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "3",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483580/946-220-50-3"
  },
  "r355": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(1))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r356": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(2)(a))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r357": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(2)(g)(3))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r358": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(7)(a)(1))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r359": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(7)(a)(2))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r360": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(7)(a)(3))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r361": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(7)(a)(5))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r362": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(7)(a)(6))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r363": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(7)(a)(7))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r364": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(7)(c)(1))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r365": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(7)(c)(2))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r366": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(7)(c)(3))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r367": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(7)(c)(5))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r368": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(7)(c)(6))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r369": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(7)(c)(7))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r370": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(7))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r371": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.6-07(9))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-1"
  },
  "r372": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "3",
   "Subparagraph": "(SX 210.6-09(1)(d))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-3"
  },
  "r373": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "3",
   "Subparagraph": "(SX 210.6-09(4)(b))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-3"
  },
  "r374": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "3",
   "Subparagraph": "(SX 210.6-09(6))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-3"
  },
  "r375": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "3",
   "Subparagraph": "(SX 210.6-09(7))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-3"
  },
  "r376": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "310",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "1",
   "Subparagraph": "(d)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480833/946-310-45-1"
  },
  "r377": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "320",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "5",
   "Subparagraph": "(SX 210.12-13(Column A)(Footnote 3))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480032/946-320-S99-5"
  },
  "r378": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "320",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "5",
   "Subparagraph": "(SX 210.12-13(Column G)(Footnote 8))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480032/946-320-S99-5"
  },
  "r379": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "320",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "5B",
   "Subparagraph": "(SX 210.12-13B(Column E)(Footnote 4))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480032/946-320-S99-5B"
  },
  "r380": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "320",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "5C",
   "Subparagraph": "(SX 210.12-13C(Column H)(Footnote 7))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480032/946-320-S99-5C"
  },
  "r381": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "505",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481004/946-505-50-1"
  },
  "r382": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "505",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481004/946-505-50-2"
  },
  "r383": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "505",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481004/946-505-50-2"
  },
  "r384": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "505",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481004/946-505-50-2"
  },
  "r385": {
   "role": "http://www.xbrl.org/2003/role/disclosureRef",
   "Topic": "946",
   "SubTopic": "505",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(d)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481004/946-505-50-2"
  },
  "r386": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "1",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483467/210-10-45-1"
  },
  "r387": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "210",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "55",
   "Paragraph": "22",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483444/210-20-55-22"
  },
  "r388": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "235",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "4",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483426/235-10-50-4"
  },
  "r389": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "260",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "55",
   "Paragraph": "52",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482635/260-10-55-52"
  },
  "r390": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "30",
   "Subparagraph": "(d)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482810/280-10-50-30"
  },
  "r391": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "31",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482810/280-10-50-31"
  },
  "r392": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "280",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "55",
   "Paragraph": "47",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482785/280-10-55-47"
  },
  "r393": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "842",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "55",
   "Paragraph": "53",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479589/842-20-55-53"
  },
  "r394": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "852",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "55",
   "Paragraph": "10",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481372/852-10-55-10"
  },
  "r395": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "1",
   "Subparagraph": "(b)(1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480524/946-210-50-1"
  },
  "r396": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "6",
   "Subparagraph": "(a)(1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480524/946-210-50-6"
  },
  "r397": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "946",
   "SubTopic": "210",
   "Name": "Accounting Standards Codification",
   "Section": "55",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480493/946-210-55-1"
  },
  "r398": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "946",
   "SubTopic": "310",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "1",
   "Subparagraph": "(d)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480833/946-310-45-1"
  },
  "r399": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "946",
   "SubTopic": "320",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.12-12(Column A)(Footnote 2)(i))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480032/946-320-S99-1"
  },
  "r400": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "946",
   "SubTopic": "320",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "2",
   "Subparagraph": "(SX 210.12-12A(Column A)(Footnote 2))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480032/946-320-S99-2"
  },
  "r401": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "946",
   "SubTopic": "320",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "3",
   "Subparagraph": "(SX 210.12-12B(Column A)(Footnote 1)(a))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480032/946-320-S99-3"
  },
  "r402": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "946",
   "SubTopic": "320",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "6",
   "Subparagraph": "(SX 210.12-14(Column A)(Footnote 2))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480032/946-320-S99-6"
  },
  "r403": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "946",
   "SubTopic": "830",
   "Name": "Accounting Standards Codification",
   "Section": "55",
   "Paragraph": "10",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480167/946-830-55-10"
  },
  "r404": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "946",
   "SubTopic": "830",
   "Name": "Accounting Standards Codification",
   "Section": "55",
   "Paragraph": "11",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480167/946-830-55-11"
  },
  "r405": {
   "role": "http://www.xbrl.org/2003/role/exampleRef",
   "Topic": "946",
   "SubTopic": "830",
   "Name": "Accounting Standards Codification",
   "Section": "55",
   "Paragraph": "12",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480167/946-830-55-12"
  },
  "r406": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Exchange Act",
   "Number": "240",
   "Section": "12"
  },
  "r407": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Exchange Act",
   "Number": "240",
   "Section": "12",
   "Subsection": "b"
  },
  "r408": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Exchange Act",
   "Number": "240",
   "Section": "12",
   "Subsection": "b-2"
  },
  "r409": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Exchange Act",
   "Number": "240",
   "Section": "12",
   "Subsection": "b-23"
  },
  "r410": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Exchange Act",
   "Number": "240",
   "Section": "12",
   "Subsection": "d1-1"
  },
  "r411": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Exchange Act",
   "Number": "240",
   "Section": "12",
   "Subsection": "g"
  },
  "r412": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Exchange Act",
   "Number": "240",
   "Section": "12, 13, 15d"
  },
  "r413": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Exchange Act",
   "Number": "240",
   "Section": "13e",
   "Subsection": "4c"
  },
  "r414": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Exchange Act",
   "Number": "240",
   "Section": "14d",
   "Subsection": "2b"
  },
  "r415": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Exchange Act",
   "Number": "240",
   "Section": "15",
   "Subsection": "d"
  },
  "r416": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Exchange Act",
   "Section": "14a",
   "Number": "240",
   "Subsection": "12"
  },
  "r417": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Form 10-K",
   "Number": "249",
   "Section": "310"
  },
  "r418": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Form 10-Q",
   "Number": "240",
   "Section": "308",
   "Subsection": "a"
  },
  "r419": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Form 20-F",
   "Number": "249",
   "Section": "220",
   "Subsection": "f"
  },
  "r420": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Form 40-F",
   "Number": "249",
   "Section": "240",
   "Subsection": "f"
  },
  "r421": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Forms 10-K, 10-Q, 20-F",
   "Number": "240",
   "Section": "13",
   "Subsection": "a-1"
  },
  "r422": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Regulation S-K",
   "Number": "229",
   "Section": "402",
   "Subsection": "w"
  },
  "r423": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Regulation S-T",
   "Number": "232",
   "Section": "405"
  },
  "r424": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Securities Act",
   "Number": "230",
   "Section": "405"
  },
  "r425": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Securities Act",
   "Number": "230",
   "Section": "425"
  },
  "r426": {
   "role": "http://www.xbrl.org/2003/role/presentationRef",
   "Publisher": "SEC",
   "Name": "Securities Act",
   "Number": "7A",
   "Section": "B",
   "Subsection": "2"
  },
  "r427": {
   "role": "http://www.xbrl.org/2003/role/recommendedDisclosureRef",
   "Topic": "272",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "3",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483014/272-10-45-3"
  },
  "r428": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02(3)(a)(4))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r429": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "210",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.5-02(9))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480566/210-10-S99-1"
  },
  "r430": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "220",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "2",
   "Subparagraph": "(SX 210.5-03(4))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483621/220-10-S99-2"
  },
  "r431": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "230",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "14",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482740/230-10-45-14"
  },
  "r432": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "235",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.4-08(d))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480678/235-10-S99-1"
  },
  "r433": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "235",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.4-08(g)(1)(ii))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480678/235-10-S99-1"
  },
  "r434": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "235",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Subparagraph": "(SX 210.4-08(h)(1)(Note 1))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480678/235-10-S99-1"
  },
  "r435": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "23",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483421/250-10-45-23"
  },
  "r436": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "24",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483421/250-10-45-24"
  },
  "r437": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "250",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "5",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483421/250-10-45-5"
  },
  "r438": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "260",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "55",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482689/260-10-45-55"
  },
  "r439": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "323",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "3",
   "Subparagraph": "(c)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481687/323-10-50-3"
  },
  "r440": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "450",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "4",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483076/450-20-50-4"
  },
  "r441": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "450",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "9",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483076/450-20-50-9"
  },
  "r442": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "470",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1A",
   "Subparagraph": "(SX 210.13-01(a)(4)(ii))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480097/470-10-S99-1A"
  },
  "r443": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "470",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1A",
   "Subparagraph": "(SX 210.13-01(a)(4)(iii))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480097/470-10-S99-1A"
  },
  "r444": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(a)(1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r445": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(a)(2)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r446": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(a)(3)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r447": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(i)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r448": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(ii)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r449": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(iii)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r450": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(iv)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r451": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(iv)(01)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r452": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(iv)(02)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r453": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(iv)(03)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r454": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(1)(iv)(04)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r455": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(2)(i)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r456": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(2)(ii)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r457": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(2)(iii)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r458": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(2)(iii)(01)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r459": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(2)(iii)(02)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r460": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(c)(2)(iii)(03)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r461": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(d)(1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r462": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(d)(2)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r463": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(e)(1)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r464": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(e)(2)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r465": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(f)(2)(i)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r466": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(f)(2)(ii)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r467": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(f)(2)(iii)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r468": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(f)(2)(iv)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r469": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(f)(2)(v)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r470": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "718",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(i)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480429/718-10-50-2"
  },
  "r471": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "12",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-12"
  },
  "r472": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-2"
  },
  "r473": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "740",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "6",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482685/740-10-50-6"
  },
  "r474": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "815",
   "SubTopic": "40",
   "Name": "Accounting Standards Codification",
   "Section": "65",
   "Paragraph": "1",
   "Subparagraph": "(e)(3)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480175/815-40-65-1"
  },
  "r475": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "820",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "2",
   "Subparagraph": "(bbb)(2)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482106/820-10-50-2"
  },
  "r476": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "825",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "28",
   "Subparagraph": "(f)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482907/825-10-50-28"
  },
  "r477": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "830",
   "SubTopic": "30",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479424/830-30-S99-1"
  },
  "r478": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "842",
   "SubTopic": "20",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "4",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147478964/842-20-50-4"
  },
  "r479": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "842",
   "SubTopic": "30",
   "Name": "Accounting Standards Codification",
   "Section": "25",
   "Paragraph": "11",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147479341/842-30-25-11"
  },
  "r480": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "850",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "3",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483326/850-10-50-3"
  },
  "r481": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "852",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "7",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481404/852-10-50-7"
  },
  "r482": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "852",
   "SubTopic": "10",
   "Name": "Accounting Standards Codification",
   "Section": "50",
   "Paragraph": "7",
   "Subparagraph": "(b)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147481404/852-10-50-7"
  },
  "r483": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "912",
   "SubTopic": "730",
   "Name": "Accounting Standards Codification",
   "Section": "25",
   "Paragraph": "1",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147482517/912-730-25-1"
  },
  "r484": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "946",
   "SubTopic": "205",
   "Name": "Accounting Standards Codification",
   "Section": "45",
   "Paragraph": "4",
   "Subparagraph": "(a)",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147480767/946-205-45-4"
  },
  "r485": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "3",
   "Subparagraph": "(SX 210.6-09(4)(b))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-3"
  },
  "r486": {
   "role": "http://www.xbrl.org/2009/role/commonPracticeRef",
   "Topic": "946",
   "SubTopic": "220",
   "Name": "Accounting Standards Codification",
   "Section": "S99",
   "Paragraph": "3",
   "Subparagraph": "(SX 210.6-09(7))",
   "Publisher": "FASB",
   "URI": "https://asc.fasb.org//1943274/2147483575/946-220-S99-3"
  }
 }
}
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>ZIP
<SEQUENCE>59
<FILENAME>0001731122-23-002197-xbrl.zip
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
begin 644 0001731122-23-002197-xbrl.zip
M4$L#!!0    ( -*#>U=)JA@$L0P  -.*   1    879X;"TR,#(S,#DS,"YX
M<V3M75M3XS@6?M^J_0_>O&Q/;860!.B&@9F"0'J9!I("NJ?G:4JQE42+(Z<E
M&Y+]]7LD7^*[Y0"->M8\4(ET='0^?;H<'5O*\:^KA6T\8L:)0T]:W9W=EH&I
MZ5B$SDY:G^_:IW>#R\N6\>LO?_^; 7_'_VBWC2'!MG5DG#MF^Y).G9^-&[3
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MT(M'T5E#;RJ5JM3\^UF_*51C^'H:#K;W<[?Q=VOYO=V#[?U>XUWXJ8D,*;K
M]VAB%SO"0:X2;^\5W&'CG:^QH:>NAQ#GJ5I,B;!,M*#46VBH4W4;XE1EDY6H
MR>S]XRY$P\0+K&/GV$7$YC>(B2<.C[C.>I8IJ\)I+Q,NJ+.N!54:49T-^8H+
M7-!R12M<F*U$82;JD+O$!2H;AJIB/_ECL$Q B:5,>"(>&VJ&TI;QHGRRJH24
M",N$+=+QI(:T%_ @$Q.A@IP2=9E81X4/V<R-SV.OJTI?5XV_3+!$C3^CVS"X
M)8,]509[:@QFPB6*#/8:!K=DL*_*8%^-P4S@1)'!?L/@E@SNJ3*XI\9@W4A*
MR.!>P^"6#.ZK,KBOQF FX*+(X'[#X)8,'J@R>*#$8#\37E%D\*!A<$L&4UO!
M.@64&,U$6Q09;?:(RJ'JQ)XP)UV)ITR\)1FL;K9\]<CH%K&AMJ7K9Z(IN70T
M.SAE0GI%A*CMT/JE[X,T&[+ZA*06GC(!)8(R09!\@OY/UQ7Q3YR,OL530YZH
M/A+'>$]:G"R6MCC_+-/F#$]/6N(D;SL\:OLGP-Y9+>Q01-10<J):DIUNJ:#B
M4 5B9D9+YL0W*'&6F(F',9W0^%"!2UQ1//[6NR'J@26P\X+(;32IBQR*8/L5
M(5\)_:^!%3IH7:RI/OU*B >;6EX#-XRNNKB3 _*58)]'E611'W>21]SA>_H8
M_#$ =YAKT,QI^K)+$/SK&ZX<4ZHJ*2*^M<-R;9'4[O;:_>[.BEL;2^L8L6F&
M>D:$Y;8PHN JAKSZ>9&X^" [DVJE!5<ZE%::6Z:#;9>'*5N;$+\ XADV2#6U
MC*B^5:+(G*J2\CO?JA/(5S;8NDY'B!<)O]1JB*0VCS'8"->S(%XF^K9=C]A<
M'Z+6&4)YOR.(&T6VK7:+GIBMO+ ;!C>/2$=3S/]_7A-SCK#]V]!9#8$T2U9T
MC1<3<?&'L/2D52Y";%N\OG72<IDGYFYQT<P1S.G$L>[ETF-Y+#@BZ"]%T<4J
M1Y:S0(1>NG@A) &M-^$PZWM"^B-SO.5)RU='0*0,Q!T&MN7K*F./@;$<G\X8
MED))*"J".@!*OH=PAVS,"Q I2>H *=/@HG<FL92+Z  "/!#3L>D8L8<!6A(7
MV4,8$%=7@R20:C$=P(CXH^,?O88=HNV)F\$V,<F[.8)=11)7K1*:0;Q8U858
M74(7B.5PM#4]9[QW#RNGA)B(#B!D5QG)H^AC&U&P;S^UYI0(Z G@L J Y@ST
M>A4 8@(Z  @[^>\B(D==WLT? ]EL'8WOE1NO5\L'G8(1$Z<:/3=',Y-[A29K
MV\K]0I/U<O1BANT5FKRGJ\G[A2;KM?0,L849LI/6IA-U,/3&H<%E7G3F/TT9
M,F?Q4<YHH=T5,C5@^'D3_V+ DY;)L$7<$)V?"3XJ=A%;OP"V6\PQ@DGZE%KG
M^!';SE+D P+X3QYQ>*^%#U)56%NT\O#$D%"H#'BZ6"TQY1&ZHLSMT5AX\HI@
M+A"CXB 79M*[%[<@F8(98GLNMDY!*T.F&X4*%*51\"F$6W\$^A*@10R%%QE]
MIKC<+23F%MOB@J_!7-R3&Q]_Y5*ZLGB.IYA!KY=317*XY6=I.[C$17EC1*RA
MP^3E:]"[1.S2OB:4++Q%XBZ*8']:IX2N!/I;ZTO./6Q]IK!ZB;A59N=Z*9YB
M(3N](X\V*<]4HFVG>!:P%VRC;5HJ,9WYE;]\Q*8H5J,SJ>4\:=OTF0Z4#)@7
M]K.,F+;$5)A>,9X*A-^:MBO,>8YITO"!PS<^N(K@#T$=3&K<@S7_WKG%,\)=
M#%6?$X9--WS4D\>A4JF_"/[BGERCK X=N]3(_"ZN7N0'(_MBA9E).!Y-8S';
M"I(+R_PEL*MT\XJ2;]W)DT9G; XCP_D8R\1_$((+(91Q6UWHK6G=O&*<O88D
M'7I0D]4N\ #&@LF)&\3PRCVS89"%R,I%GA&[=$,U+TI5[#:28HYRA;0C)WZQ
M2F1ZAI]**>TH2MU!4DQ3H:!V5"4MS7!4G*T).5?$%)'@(0XN?UQG()1*:((B
M%D0L0%$JH0D*\8MYEF<+9T>L9.GGRR//%2]CB]=VY+5R&8S/**]G"YR!]=88
MK870[YC,YB*8_X@9FF'QFX;2H%/P*A:^6ZC4*L_5J4E+!<[&P"94_+[.'9$!
MYC'4#&)?""<N3^RM:LA7(O0/!;C?V_4<DA66IY7% B#Q(#O"5Y2I*YAK8F/N
M@C[9'XM054KI"B_G@<\/\J"GY%FWPN-PG9'E/''KECR-Z^J,90Q[1W$L< ;3
M.A3D?,P<$V.+"R9DF#1Z2TM%\AF3^M+7_Q*+GV.+AX4)(T\7XKA)M)2526C[
M"%&T\6@:A:U3D(IR=9W9Y(\I![X$'TUL,A./XN^=T-L*@2G(Z<K8C2?>3RJQ
M'?H>&(;D:Q;1I%BST%O'>(:(L("CS%/5R*DHE]FZB[XN?3!]BP-B5O"23S03
MYJ1KBF#CJ(L?E@1C?:]<;&-F_L_>G:TSSOSI$V)6$""&27**H6;15>A8XDGY
M^F'TD<MW!Q.!RN]<\?/6'O^YB 9-'N'ZO@U>NUH]FCMG3UY@>-A2M4JHC^M7
MQ.@SY$?]D^_K1FEOO0B$;N\]6L&>'[L\_R70X*0;^6]@2])GKEM8TTDW ^<S
M72*2?A6Q4DI3=# Y+!"%I',B@K$8JN3R-4H1#7/DP\7,-!3;0FQ35E?WK@(.
M-H7&[D%OH8@_44!7T*?6?SPN';=[)^J[DK41#1#T/_2B:)FJM*YPH[=+;['I
M4)/81%IQXU +6QX  *,#/[!@UI*[J!OLQKS'E].H;5PABNN(WS ?P)*[GCI,
MN!OQ'_[=+&9JPF_]C"IKYS"P$P@C?M5_ &/%N KEWQI:?E>#7NKW-AZ'I2C[
M_2 ==_Q+,.#C_P!02P,$%     @ TH-[5SFZRQ4;"P  NH$  !4   !A=GAL
M+3(P,C,P.3,P7V-A;"YX;6SM75MOV[@2?C_ _@<>'^"@^^ XMI-TFS9GD3A)
M82#;!$[;LV\+1J)CHC+I%67'^?<[U,71E:)L2=0"FX=<',[HF_DX0W)(TY]^
MW2X=M"&NH)Q=](9'QSU$F,5MRIXO>M\>^Y>/D^FTAX2'F8T=SLA%C_'>K__[
MZ5\(OC[]N]]'MY0X]CFZYE9_RN;\(_J"E^0<?2:,N-CC[D?T'3MK^0K__6IV
M!W\&CSM'IT>C8POU^QK:OA-F<_?;;+K3MO"\E3@?#%Y>7HX8W^ 7[OX01Q9?
MZBE\]+"W%CMMQ]OC\"L0_^10]N-<?GO"@B#P$A/G6T$O>O*YX6-?QD?<?1Z,
MCH^'@]]_NWNT%F2)^Y1);UFD%TE)+7ERPP\?/@S\_T9-,RVW3ZX3/6,\B.#L
M-,-_J:)]#(F@Y\*'=\<M[/EDESX&%;:0?_6C9GWY4G\XZH^'1UMA]R+G^QYT
MN4-F9([D3V!O]U3,\(9L)5T#^:_!A$,G!)R^T,(E\XL>WFP=T#T:'W\8'TO-
M_TDT\EY7T!D%7:X<,'"PUU.OL"/]\[@@Q!-E3\]M7#N*!^P2YBV(1RWL5(*4
M*UD'/ADJ9 FZQ?W\?B6#&OJ/N&3VA"]7+ED0)NB&W'%1ZL+JFMK%7\GY!ZJM
MV[()%HM;A[]4(B$C5#NJ!6;/1$S9H\>M'PONV)#\;_Y<4^^U$LYR-;5$XEI0
M1H2X)L)RZ4H2"GQ>84$!PX-+!*#Q:2X-S*J*:O'[>KG$[NO]_)$^,SJ'SL:\
M2\OB:^;!</[ '6I14MX]*FFI S=H=]?$OJ/XB3K4T\!8+%$'GGL(57<*LZ E
M*0.2T[0.!$'/OI_/B0L^+W5'0?,ZD$ N6U+/CT(_L_F= &:(&B1IB-:!,/#^
M5[PM1Y33M)ZX>Q+DSS48>K.1UI9'6'[[]G) O;F@G9SP%3\Y^V2&I%S#,:$'
M4EM!S?&AAZY0H+W^>4T\3!WQ!;MR5K4I3<.':6VFOX9/J]YA4X(UCVA57:LA
MVL"(5Q6EIGC#T:])N;Z&=O .#P<\;!?QZ'#$HW81CP]'/&X7\<GAB$_:17QZ
M..+3=A&?'8[XK%W$VAEY#U4USW8TLW&Q1#-X2K.M0J091*795"'2#"+M7J8A
MJD)H8<=:.WXAY@[^3DB0K4>83>Q(CX2J5[[VJ">;AOL)0]27FP]K&0KP:]BR
M(1SY->H$GA& V)76?$!,P 39AE=L%,JC4$$(,H+I<"L!S9%["3Q5MH_V9?P=
M@SD63_ZVP5KTGS%>#21[ ^)X(GK%Y]/G,GSACTLA8N =_$0<_U%_A VB_P^,
MH),54YG0X(><=&ZPXZ<X;P+][A52G+^?5 Q>4SQM6ZR#7+H6XJY-W(O>+B]@
MUTITB^R.3=AB(.1*2:KI4^@!D?S<Y<M<'X?^Y/O8$.<"'M]#+X0^+SP?MAGN
M8MEB1BP"R)\<!5<%S?6X&9GA1FEBE[AX<,D*4_MFNR),$.A._D(SL&VR=N6&
M23$S6L)Z/(W-\%3!_"ZQEE-QS[*3:&0&9UC\$0_X509 :8<J:F\Z#^?M<' M
MY-WK.]E*EPXM12*FL[ 6,VI[NT3.-9D3 &?/ -\$?E(%*WEM32?;<CJ*+>P2
M#\7[VUD>\MH:&\P#Y_J02J; N8U-)UK%N8+,P%UD:I?ZD2R_<*9#1[:EZ=2J
MS461D5TBXM*&3 ,F8^<!YGM3-L$KZF$G!ETQ_&G(FDZ\VF3I.Z)+],UD58D1
M^P:[3.XLP:"^7DK_$AL&%&JIQDD=63WZ3LS3I^^(+M$7FQ; &JO*X%HN:7K(
MTK4M163AH:DRQ@S.L*O85W9"L,C,3X.\4FP+9=K\TZ&)FNU8OV:+WB7T_=Q8
MJ7F/L[P)FTY4-KTI1WR.WM0CS&R4> #RGV DN82PV'-8Q5&41'*:FDF(P;LR
M'*#ITEY21H47[):$N(HM*!4TG0X+V4CE!TT/=&D4FQ%! (DLNE^3#7'X2H9&
M*64E8J;SNRYA6M9WB:Z=84$Q/IX"%9DAWK@SL92U($5.,8E90OK&&/G"&4^:
M5!H\"I&];,CN7<M7)+*4LV^!C,\N9KE;H%)&+6*ZZY2Z.NI Y:;4'MD%'.0G
M&, #WV%@2![O3Y&A*6LZUU9BI9(_NI1XI\PC+A%>PL(O1+%$+Y8P75?19JS4
MDK;"R-_!O*4,%B-OXT%!V!2T-5T-J10F2GL[-?S=<A<PL&#[R7K]"OE58$NZ
MXS.F3([N5V0.;;[B;7&H5%*B1^2I>2+W,:Z+B2^:ILGQ,SALN0;3WQ;. ?S8
MZ9";+:Q[@ ?HO^[K%'PIP&<62(*;'=]K03XI.Q[3T$--3V-:\&C13#IGSMW)
M^ES[+BJ/Z@[%)(R].NN_5#/3_3X7=>X9LV:)[Q"1X:F-G35AG[LBC,Q5VS]E
M<J;C5X=J/=M+)CMM5M8/O90A4:(^K;%$;:0NG[W>(6'?F;Y]4A,*5)G*IA+"
M@\LW%#QQ]?I-$'OZ5CVXA,G:IN1<8A4=_XP9E1))16[2XWIN)FI\P2J'(!D@
MT1)N1OSM[,D"N\^Y_2@L62F%.I#5]R1#Q[KNC<Z/ (U<83!2YEQ(N(EK57(.
MS16T-U[O.32(U([H$F40ZRX!H-<D^#EEU=^8H:? >#WI4%(KNJI35:<L]N2;
M'JKPFY8T7E^JG]A\YW2<T=2[#ZI0FA'5X_3L[\1I@7NZG8R++]?2I#4CK<?L
M^[\9L\H;R)J<MT;O9/#W296[D[DM]=CXI8-L%)K4P5Q98.5N9GW @C57AZDW
M?G"+$-LO!$Z%6,N#B/=SK</M&J(=7=@J.,R\6433/5T:$6"P"LM'/L0(]X0+
MU;ORU5(=71578%+#*9W*/_&N]W]Y)X8\,D=<BRK/J:JE.KI&WB\>BYS2J5",
MX?7[W;U_E:R(0-MZ3!:(=G1UO!^=2O=TB5-I<NKJC!D1GDLM66@+KM9(OA!K
M^4!<RNWT=/1F:SEKVS^$8OD7)<^P1V[F<V*IMJ=:QF%Z,#?C]VREN^K<MY-[
M_UUVIBI_=.8=0%4O-T_LV[VOL&\7Z$:4H;CV_^(5%Q]1^JUL=;_-J?(MZ DS
M?Y$W9U%A.5RL70)_1/I03*&_W>JKE.8FE3:UPUKMAO2$31_2-H7*)/B8.O2F
M#[TI;,@>12TCCGUXG,8>"J+<8D_-(/-N6D^@&Z;1^1(H7?6H&5;1U>L):*,T
MM$ *Q<0:NY>N_ [V!-1Q&FI,0WBR(:&C(=QY-[4G<)ZD<082*!1I+/(+;FY/
M8#O-QG@DAB(YHZE)F:*&9_NG*/0N^JVY\RVE-[PGC'FOD;/0NT!#<Y@58:@"
MGQD E<'8O!G%-\,G8&?&N'AL-H_RP,O@XZ:,,D->E5@('X%VSV@S*-)WV2;,
MRHR5N5$1JOC9T#6@C5X7=LC^2_B8";241_D>8:4$4?T -,*COE-!/5%4+)7R
M^N*FE\SE-YCQ?<SJ7DTFQ'[%V5KH][-T<].+<FVZU&:TM8UY2[?$'PM=;'D^
M%NP4Q4Q!6],%Z4H!HK2W>7?_1F'4]3B+SHAI^;U,R'0)N1(!>A[H4EX*+H6M
M/A"6R9D^/E4U4^GYH3O5/9T/S4E,R#(5@GCQHM69I.XGZ23@9ZH&Z0)'JR:4
M?_1$OA69FD+)<FLW/S9GR##?DDP%0L\2-#1IRRC?EDPY0M.6D4E;QOFV9*H1
MFK:,3=IRDF]+U>)$9,N)25M.\VW)5"PT;3DU:<M9KBWC3,E"TY8SD[:HQY=Q
MIEZA:5,+@XWBXX,2)F1&^&11K/&Q1/6I0@F@F;$\%VB30X7JXX824)6; *V,
M!#J?/Y2 G!F9\R&G.VXX>97?GF#Q J_\!5!+ P04    " #2@WM7F_IX!3@8
M  #P@P$ %0   &%V>&PM,C R,S Y,S!?9&5F+GAM;.U=6W/;.)9^WZK]#UQO
MU5;/@V-+MI,XW=DIQXY3GG+'+MOIGGE2T21D<4,1;H)R[/GU"_ BD2(. %(@
M 2KNA[0DX_*=\QW<#PY^^_OS/'2>4$P"''W<&;W9WW%0Y&$_B!X^[GR[W3VY
M/;VXV'%(XD:^&^((?=R)\,[?__<__\.A__WV7[N[SGF 0O^#<X:]W8MHBG]U
MOKIS],'Y@B(4NPF.?W7^<,,%^P7_\]/-)?V:5??!.7HSWO><W5V%TOY D8_C
M;S<7R])F2?)(/NSM_?CQXTV$G]P?./Y.WGAXKE;@;>(F"[(L;?]Y/_\OR_Y;
M&$3?/[!_[EV"'*JEB'QX)L'''59O7NV/@S<X?M@;[^^/]O[Y^^6M-T-S=S>(
MF+8\M%/D8J7P\HV.CX_WTK\626LIG^_CL*CC8*^ LRR9_M5/EAG*B8_VLC^6
MDP:"HDN@2?"!I))<8L]-4KN0(G+ %.S;;I%LE_VT.QKO'HS>/!-_I^ I57:,
M0W2#I@[[/R5Z6:L;N4_HF3&[Q_ZT=XJIO5*<::99C*8?=]RGYY"6/3[8/S[8
M9R7_=R51\O)([98$\\>0"KC7JM9/;LCT<SM#*"&RVKF)M:.X=F,4)3.4!)X;
M-H+$S:D#'VM5:$[+)E?3JT?6_JG]D)/(/\7SQQC-4$2")W2)B52%S4OJ%W\C
MY6]8K&[)3ETR.P_QCT8DU#)I1S5SHP=$+J+;!'O?9SCTZ3CQ^:]%D+PTPBDO
M1DM+7) @0H2<(>+%P2,CE/+YR24!Q7 =(T+1I#1+&V;3@K3H?3&?N_'+U?0V
M>(B"*36V*#GQ/+R($CKR7^,P\ (D-X]&I>C 34N/%\B_#-S[( P2!8QP#AUX
MKFA3C2_HA&F.9$ X274@R"S[:CI%,=6Y5!U <AU(:%\V#Y*T%:8]6VH$=#*I
M0))"5AT(,^W?N<]R1)RD>MK=/4%_+:B@GY^8M/(6QD_?7Q^@MR_HIT^X<^_#
M-CU#-5_';4(-I'(!FMN'&CHP0W_V>882-PC)5S=FLZHG:3>\6:G=V&M>6W.#
M7<NH>41KJEJ%K!V,>$U1*F;ON/4K4JY>0C]X1YL#'O6+>+PYXG&_B \V1WS0
M+^+#S1$?]HOX:'/$1_TB?KLYXK?](E;ND5L4I7FVH]@;PSFZP2/M;059ND$D
M[4T%6;I!I&QE"EE%"-W8*T#R$I?K!O;"BRUYM@E^E$*:T2)B;W&/=OU@SO8
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MJC)7&Q9*4-8M!;+CX)A:TL>=T?X*2X@)\C_N)/&"(W+/!&6VS7HF'*4+W.=
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M66HI"[QQ:M/BYRK.YBBR]UWE>2UFL*$,('.:W<?.W2#.N^[:@XI FQ)EL9@
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M9W,]J@TTV=*A1G]^SIF[_9W[O'0&YOL C]=]@+.,3IISZ?+;F0]S'>:(C_-
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M1=G_2S?&B;A:. @]E("5).E)PJ.*"IZ-,$('4:40$^N:KFQ#0WF4;/"[OR/
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MIXR3SH@5<C&/)8VSV]R*^//=8T0K\'I;E6P$I<#TJ^!&)<_;"PX&##89#!J
MJ.< 4[?AP#415SU!0AEUM /-S\K=+8 X^?!RBY>8L',']_BY^D _]-DPPW#0
M]3U[<S9G.)FS*H(@X5BTNJE>B;H%H >6(U87@7YCA2!>BN_WRR_C)>&)) 59
M5!6F78,G,:E/&YB$?='.#KCAF5X2!+&L\(9,NCR]N$6U!NJHA#B0L'L7A'KF
M=75.2$%."SI\QP;ZN"CY?YO%9H#\3(M. P2MG&$:'F^1$LD0+P;MRD&_L9)\
M.ZN:_)IC$;U?O28D]B'U<@_%3R"8(>-19A32=@YPT*'^-+OR0Y/=+DEX;N(A
MM$$S-S]#:NH!)EUS-V)AFOPB)>M+U1;%X'?/S=V'-6AL\2.DINXATC4T$T*7
M9Y.V\S(J'SC4;?EJ%44;T=@XJ\KF+[M6K__P>SNN7"_;P>:F$'MGBP?V_$L\
M7 H:I^J#*_L8PV@T1B\XP_8 *YV):8.(8MF)+1IM]%NC/VTTL0\O%V6)J]+"
MP*&03ZZI 799U9< PQ\E+,E-<2$@+*@7(YW((,GZYX0&KDR-@2 PAJC1:5X/
M#,Z4TZA\7.0)^\?Y7[?I4Y2QA9Y%=1H1\I+FJU^B;#N<J8S4]<FD4>9TF>6D
M"(9I8]!*S*-**,H3%+-_P3OUX%QDJXMK?!\]X_(6QYCB>I".BUMD?7+-"+?+
M+:4@&"Z9T$GK=[12<IZZS@A41<^(M"KA^7-#\"9*D_/G#<Y+3/L'SR?I>65-
M'3AI^N36"%.Z3'-0 \,[=ZR*FZZ8)L)"M>1D+'CN4%P?T(D@Q6'&<"%$I*4/
MK;RRHRJJ*+NR!E2ZZRV8-@(2<%^ET4.:T=D@+BF3^7;M8Y$EF)1L?*Y>+#&X
MN[I/LHPUJDLG5UTP[F@D8.FBYYTZ=T?= OX!B2(@L=1M;FA2",1$AUFB7AHB
MVT;-%U%',3B=ZLSO\B9Z80&@.<32"7L=_8R >Z.A4A(,?8SPI#6I6AAMA#0$
MWI M3N0^H+=6)^^9/6;8 P*IA2%QR(A002,FC[+.2/>*G23"Z'UP2IVQ1"2"
MDUN*_Y3^,]5Q227HDT1ZH%WVR%)@:*.%)B5CU()H12(Z<*5\F:%AS/?!&=/A
MO7V,#A;M6,(;6-,U&9AZS@8IAF$)MFG%LQO9@FK!#[+A/-;3PJCA=:W;#KVW
MPJT7!^-<[!CEA[-:#3[OZNDTWN9/P6EV0VIOR.>%IDT5I:3GI4<=U,%2XU ,
M#(WTV.3-D$W*7%+)!-%B6ST6)/T;3GY\^^;DS1O^?VC3E":D3F@<3= 3*Q3]
MGS??O7GS%FTP027+S0_.L\Y) ^/.G23FVW&I0 Z]55<&#+<TP)R)A=Z]V5$K
M%L<[3+SB=]<E8HE[=^[C1_1/[T[>_.E/)W]\^[8M19P.^9:2XAWU?/_XCR<_
M?/_NY)_>_O$/P6FY2!*>*1-E-U&:7.9U[73J4C=)<5#T.@=T-J0W&;1J@:&W
M,U1I>M@J(K8Y\RK-42QT@[/O%E=1FN/D/"(Y.[!'9[+;]39CAUCH)(4]VZ2I
M#!=%G^QS-Z3+/KL6&/8Y0U4L3C2"*!&2P6DG[R%HK%8)^DW_U 'M)WL.I6#-
M/K7XU)-0Z!LTRDVH/?>N8&T;[K-="(MJCFBMJQ]P=PK[,RAQ[G@7Q#I-NV2E
M<+-8G0'Z">U0 \P0Z013D3'3G\)&K08PJMU$Y)KP?/N$3Z]N,.$V.M6&7CD<
M]6P&Z2FHTP1*10M<*R7;V6]P1DK7-5@]GU$CT-**B\\SB(-AF1VC:DVX70\!
MY>LZMHQT=$Z:@9@VQL4YJ$%DWDCG-F @8-<FEA==NUXC'=2E]2$;W9D0A4@H
M!3X+B5(N"X]!^ENFW%2"<DESPY2+/%Q6V6^7&E"KF.E"J?T/ ;4G;BT)JEII
M_P>!M)#EHT"2*!@NF?$IC@.QG)[=\6A !Z&O-YA$+!6@/F!B.Q-MD/?))2OL
M+INTPF#X9$,HW0#<R+>'>X(3Z2><4TS9(D\6R3K-4X:?'8&K+=(8;M7R22I'
M$[K4LJB (9@;SB'-:BV^_AKU](+3[1:7F-8E.]Y[AI]P5FR89S63S:+C=XO2
M 7Y_=]*@ (9F+BB')&MT.,N2G59PBDE.V=5Y!QX*G89 6#M%.GCJK:$"WNC7
M&B!BO:M">AO**!F$+S)4)6-V8D Y(P'41TM9,?%+4?MPY6.1%WWLS>%N<^CM
MH.>31\YF=%EE50(SE+DB53_.41_C^+9Q4 ?G%D9/SQFGTIL?WK_A=&)_82@'
M_>""-M)/["C)T $YR/N@CS-L1ANK<'"ZN"*40NO.:9^9N*$.QMJ[2010E3F.
MBM[8,LJ0EC9.6C#X,P:J:_C,N%5?0C,-RR98LJPPK;:JYTT_8OV:I4[<[Z*E
M&71_U5(M&YQDC@#E=4LA7A/H!.7XX%F9QE?Q4;.^,K*=!:BZBD;0FR\R FU]
MCU+*#PU^$#3(\8KMPJH":"M"=4BS;(2;65=PAW)1$)RN<G$>.W[AKS)&_-+R
MGZ(T9Q."#WA)9>ZC9TV'&%6"3[>SAVE=3S1"'8QS&H]YR-.Z!,K/^)'^'0.?
M[HV=> "9WHV:UL%:,K#!U"PW=69TDXR!$VW^LB[!YAGB+.^6VE1/0HJ\[BJ=
M.PO/G^FDM2 )=>+DA;T36=+*H#2H:,UEO#K$6&_<\)SIB_XWH6>M.GDC>Y;/
MP>I:\QLZ[)PT;N4.'CWP@M&&%$]IR>X9I__9+,!4[$/!^VM]8TQK>^UU/N <
M+[6GZFQ*7A."G SHI009-:"$PJ/0:M(ZV/6N=41\TERL&9QQM'-8=R(&,EZ#
M"Q6\7D#1%0 3HJI0:=T2OSNZ6&\(?J3<8.LP4X2CFOES?1*TR;?]$)5IS%:3
MTFQ+J:_96!BEZ6V&/<Z4=LKMIA:<2N.QJ@C&^+>[3@/Q L0"H"@BN/_YE4[$
M'IDM3W3X7V'Q)OGU4DJ\M&QYC2_&IQ?;U\BNHQM;1G "'PA\R.:F&!2)<E#.
M"V(OR-07=72R;@$2O3F"W^O+FBK3R/JDK!%NEY=*03#D,Z&S^\L3P2-PW*G]
MOZ/-K71(_@P@FQA4BX+E4!^?"XO.@/@@5U=L\DTCRX XS&I]V:@"P/!S']0'
MC:Y0W*+&\+JWN9ZF&ET* $K;3'0@M:X(Z+2VX#Z0V% \=>=Q1?:^U$56?+$=
MN#&K!'K^4@M>\^RE) ^&C@X@C<]<\F?"N!:D4UTT6F' ;MB2>(*3#R^?2IQ<
M[I+4%G&5/HG+S!4K];8\U(D*][S@.&&%#%8J)R@93'^8U!SEFWJBLVQIL2C-
MT2XW>U>RJ?O 691^Y[7-Z##W4)38N+NMA*=;GP[NHQ;)?V]+<24UV_>CU.![
M@/?%+6:-E6:X9]!]X<A+VSNNLW_6[T6K?BJQ?TWKO-\$XPL]&2I?$=M^%E4%
M>SI2?(REGHBM)?I7]N_\9=+&D1:M$_YQOK,&[(MMTN MYA>)GM)X>R4=CG/2
M\'G>P %Z]\2!03PX/]TQ2LZ_R%]QUNR2.8G00[%0##XL-.NYU)1BS7;5.:EU
MT;M&V.NTR BX-R%22@:GDQ,\>1)4Q)]?/3!IOLO=B ?G#_7'!%-89UC\L^.!
MZTNZ[7>E.!?@.7-MI&&#1#1';3!\' U9FF[P+."2C8Y?"O*9>;OZKG7T$%')
MF/[6N#\ZI$XX@L[ XI&O?KMIA^7OF)?!752A996-@WU<CXC+MO4?JG:NDJ%:
M6$JJC3!SL:\#GX1*O$Z/AR=X4Y0I@'>D9:,&3WTZ5X:D%Y9_&C/,!!PH05N7
M<@4,_D%6I2&#QT''U(&D&IQ[&F.L]!OH 0XAM6 =WG&=:5VE>0&47PF@/Y6O
M%/.V@F( V2Z;*&2@C(86?$Z/L@;W/^Y[,P=O[D#=G3ML!P[6D:G1N%5;.:HU
M8#K/C9PVTT*RMEVXG&,O>G3A -B^9X4X](21)8,9O2<UQ[ 7O:D_@!Y>4%NX
MXWZTI[=?BACCA!^M9'>ALZ6KZZ7]64@'/;\OOCB:T7_LQ:($AJZN2*6%GEJ6
MI1/UWB@-S[OHA6]#7B\Y_@;H:5%*MXNYJ7AEFP/X'M$,\E#"V!%8I0T;?E*,
MOXY 658"6,3I]I=?(\(B[?-G3.)4?]6J6264+].!U[FQH3Q(#Z8!*:\3"A7$
MJ@?A6IJYLB^B %@\X]WE>L,#A,8T_3M]5KU0C#.:H:.=4@DD]TQ(W0DHWA0O
M1#'!6>@>S!X<#4.=SAPV93F*R;L>MW;RWIU][-)R $W@F9WL_]B;JT]1QN*.
M6TSG5FG,\HWH#XL\Z?^A(WF#25HDPW78\^<XVR;\XCEQ5=<MC7C.ETNLG>C[
M!N'U=I4@%=R[K<4K E@].8CMBLU^KLE6\;A7X+>'L'_!NX^A9$N8;Z@>,3N&
M2C]\W+YAC@8YHIX[>4?TVJ\$ >^JB%2S]2[3TIVJ@YR@![Q*<W:LFP6 ]C[R
M]T,-OZ=51,V?Y^9+MR8Q: 0Y,/VK$RW\)#IO-YN,GR.,LN;HX66^+,B:KU_;
MCH6Z:GM-A1YG4B\WVDT5S'1U'%YI,:ZCO3M"BCH%S)1KP.<L49I<%.*97MK%
MKJAZ]G.:I^OMNI.?J-I 'Z/M+3-AO$EMPH*[:G#>[8=7Z1QY7A^[([-D97!?
MR2B4H;4H!M;=F>UIZWM#7M]0*,BQ^'M=QEY?(CB5C+#TA]U_XV+AS[:WB*[2
M'/,#>3;[.H)!B"$!59*CE8)'D"$T TF8*.*R1J;,6NU%_/FQR!),2A8P5B_J
M:A]*!0F1K?,G \YA*WQHYS[UZ9831$/?;?B\-=<K>P)?RN-T[4[8BW5<2>-X
MB\X'P1,45;N)\\E$R0>: %1 8QO6./F44U8SD1M:#X]1B1<K@K%X^BBM4AI8
M%^MURD]""S553'1@@=["U$D,;R/7@TH+/L!,9H(RR:$460X)VK)2$2L6;>IR
M4=04C.J2T:YHP,R?B?_'U0OFZ M?38^8OU],-3),, .@,=$M;K G9WQ;1&S%
M_,(B'E,L9=;S.S]P-$.*6TU*P:D\%JF4T-%0\@C8IG3+8Q2A\$UVK>Y:1\$X
MHWL<4&[F$-@EJ@T8J%IC3YCAI&.$Z"O:<P_@@L=DCF$6Y,AI5# T6V#C&OC?
M11DNVWC.*1(<JH0+V-7@]<%X7QX&7=Q N@317!&UFF$8-&)RJ%:$PB;7"9Y*
MZRB8-7J2-N#7S)[J"I>E C W1W7HQU7)&[^<#6BY9=6 P2M7F$-.,;T?ZU>B
M)CS[X^"G:$S-#B55[+;,55JRIQR3LY3@N+I>+C&1=P'V*B&(YW(W3>G"[.HP
M.+<79K-3V]3%B'M-FX)0PDM"15T4"':Z#:KNY0!EJL.0ZUK(,;)VQ(#LQET/
M([31%OM8[:SN==0>:51O_';4A7(OUIZX(0[MS>&\^AQR?63/O5OJ] ,[2[-9
M%B>I5H;L'(V(W9WB;&<O)Z#DV-'<7 I(>HX:R4U%'!]5]QS%M83UN"!XLY4L
MJT_>.[#5H!J(HE9C-+S4ZD$DHPWL?@R<ZKZ$PTCGZBBM!4 CH)-[M&@?%1E'
M.44C(\$D?G1>1KDO%DF2,F\=9>Q(Q&5>WPG/+7L8OF)PRPZ"E6F%[S!Y2F,L
M-H79.RZKG)=BRAN9_[.!G@R:M1(U3P;-\LW@'=.SH>K+G<:]QC%WILD^*?CO
MX9U2-: <ML*Y>*3>/?M^SB;@'GMT,CO 8\)ZD(9T=EP__ IDX+HFJRA/_\;[
MY"F=8!19FHASHGER0P&R@Z#L/Z^7]04RU$LT9VIL5Z!.5+;/(6C2ZN@2>I*"
MP0PF4UHS["O=LD]0KW1^(K1;/HL%VR^@W2<@O7A[4%V=I66<%>66X'O\7'W(
M]#>J3O^9H^EWADJ:K LJOO%U]$:]8=(@MBW3')<E.L-E3-)-VR,_1&5:LJ[8
M_5CP?E<_TL'R;&F%Q [OKQH4O$Z#K,![$QBM-!A^6B%JWE=A(6NC <FCWZ5T
MXK-,XRBO9--L?MI5V6O^_2B#>G&ZDR88)HZ"*U^-LEY'Y(4YNDXY2$'6N9YC
M:5VU_%:,QK>-T//W8,L(,W8ON#@H!:?96*2ZEWVN9G_9AWZ) NQ"T_DMN[@W
MXCB ;OEBD 65;6''&8XD.R9?5X^8B$M\W!R-4B& AS$ 5[@6A30TGZ*'*,VC
MF22ZG.2!* U!.F#L$U4G#6\4<8/><L0L#LJC.$$-0)8=&+%8W>24.88N6J4
M7L5B@,*S:#2@>1<S3&E7@4NC5GPFXO1!&=V+5M0;22Q@6VIHY$!Y$C/&N=EP
M^ W0[6G*<I$GXB&N%<[9!*T3HYO7A$:6X?6&YWW,ZUW;.Z: X)[J$-3Z<[;B
M]>A>*6A7#*1%IPYF]TT!FU(@OCHNV)LU(#+2/> R4C XV=K[6IT=I5'#\^O1
M-NB#1Z-UXF (9L>H>+2!W9-+58!Z,X5)-E]F5@E,,:,?,\E#)IG-A^U8!L!E
MW6T?2OS7+76HYT\.N2EZ<;_7TIM!]^^A5\N"89 %H+R=TH@C(0_)/PUML>[J
MZ>5#\LF\=Z<3!LLH^P[=@%+!>?2)Y;V?EU6ZCBKM=6Q#(9^,40/LTJ0O 88;
M2EA#0GP2QP5:L>!\Z*7G\.WB%_L<SJ3B=P9G!]^?O^GEP?#( :3\L&=*IVD;
M=O\-)5>O@/ $$Z\3#1^#<V.:FZ[O9\R<S1F^2655A$/"$6BUSTIU7I0*3L-;
M7&):E\RH,_R$LV+#ECK.G]GY#RSLTE2%DZ9/"HXPI4M !S4P]'/'.B1?H\D)
MV-%%M3($)M)(<(L[QY7HM)4B3)^T\9A9Q2_W[.#[I-/+ V*;%:0SS5K->?>N
MK]*8L?D"8\M0:I7V=W6-%?+NIAJM:'#.N.&3+J 1"HAI!'= YQ%AKY>P!WGY
M@3&W6,RJY=,-.9K0]406E>#$&H=3/L]7IK%P1FFVK5@V7E&6[/U.Q$L)3KJ+
M*"7\6&[GS,=E7E9DN]Y%EIHJ<=3U2<!1YG1IZ*0(AHQCT XIN3L&U]$(S\."
MX'25GVX)P3GM5R3*RRCF5]G08)/_9\8GSHY3U /*\\K70\WN<7C?PN#P^D +
M)*Z+\E!3(.H4$9SR=WC%^MXMWA2D/5[RXD9O1UVO6PICS.EM+[@H@J'H&+32
MMH/0Y?' 3[A8D6CS2,.#MJR9)B4_L2MPQ+3'85)BDO8V*;%#;B<E>M'@G''#
M-V0)5YAHFCI=_H6;7]*+!\F[</ ^.EDH";:..&&G7+"ISH?A=4%T<%[BM-H2
MVUK)_L5X?WMU#R.EVVQ&E!'<PQT(7'Z%F?[V2EP"=>IX"93?:?+/.&(93VP8
M'Q.OC= /,EUV-4LY9;8I@V'I6,32=(+J(UX ZI00WK]^Q%\ZI]1)D=-_C7%G
M*<"-I..+\<G5?8WL4G9L&6"8NR=P>7N$[8)D+VB1%!NV&MF]DZ!7:G!.W\6/
M.-EF^'HIGXZ_CQXR:QKPF *\Q@FC#>M%",[:8+@[&K(4%=0%L"2:C4BIB3)^
M2621\WQ0^O>H/NR>37?8_6 *7]$Q@K]_X,17K;1/<EH@=YFH$05#.S,^$\>*
M#281]XD9*V.:1RD.9M,97J8YY@?92/JPY5EHU(1=%KZ;6QQ?C$_^[6MDEYAC
MRP##V#V!FZ@<=\HJZP?YJD>,-E1CKEO:6W<O]DGKAXF;.[T[MZ :^7I@6?[N
M;C_0W-TU[GL6%)R^4Z W<5B\#]0\B=U>Z8Z*79G!G7/'_,ZC'K=%EET4A").
M1H:LCJ6$B5M'F:@.7IV*",[LPW ;.=UYJP6Q'<ZGM'J!Q&+E>E[7^D4->BRQ
M]RXX$-</K @-_?<L%6*/.,P48R?A]RBF?V.O?.3+@JSKNYT?J.>?]GFN"7O.
M^7J3%2^X>0-!73V+C,/@5^W6Z:U_PXEX+X$_F.?>H2;_7IA^-E.UJ;O?Q!\#
MV"OGL=#465<XI[/FC.<V1,DZS5-V1)=G7.,ZQ9__1KH9VDDG0QM/=!# ;5K"
M*^,F>F&?_A6GJ\<*)XLG:L$*LP5^43\E]4#"P8R>JAQ8?JCIRR35HIO2'%1X
M\$XVET6F3O6E+A-%HE 4[0I#=$1$2[8CQ1]I8>(XHOVJ"2I97 IH7!0)"1\P
M18UW5TC0?Y15&B_RI$[5&QE.[EEJF#'NH"I0CV1[%1F\*TUKAZD#92S;_H$7
M2V-(GA)3P4B):4T_PTM,"*9SR&?J*C"_K6S_O:Z1I87I"'N9K.X HXH"2/Q]
M\)L7?+N[8CFN:(PEOM#A/QM&,( MC4Z\NEQB-DW<=?[;J.(G__*85@4?2$?V
MA'V*##3WV=MXS?1F='D .\;>1IAZ!^FIL[]T.D4] 0G>*]@Y_8NSR]/+G.WY
M)(LUR]#0U)=&UO?-"UJXPYL6)$$PS#.AD_+ <,+GN@G>%&5:41)1'?YN7UR0
M34%@Y"PN\BI-V*E#VHGN<+PE?$0Y?XZS;8*3"]J(;#%@VSSY-#S@:.3=1&5[
M?2UIRNKH/:PT1<%@^L&4UDC'K9NSKV)+CTU@-T7%SN5'6?:"FL^R(&9-W?.L
M+]C7N4BG5#*-H^PNK3![!8V:1?'\PIZQ+?D:F&H5P%W7YY,GH\SIOG_BI!B<
MH/N@U3V)$M?ZB+U6S%<B-Z((],3+ )+R4\/]4.3;$I?B$*/A43J5K.?WZ/1P
M!T_1R8+!">:"3DNHSK(ZY],#SO$R/9Q#&N]UD3[7B4)17'$04:9T51I!;W[)
M"+1U0DJIX(2P0I./UC]S+@AAD9-*I6?BP,]IALN*3O;KC1T[&6P:WECA!KVE
MAUD<!D^<, X)TRJU#]]/3)W#'R5F[_W(>=OFL<BFY/7!8"<#>L__&C6"LVT4
M3&F\RC)4\"><1B;,SQ\VN#6.WN!W7ENF*JHHN[)'$0:@P[:Y9T6"/,C06ZYF
M*<H?1'3#LI/+87JRRY*WO8Q@&Q.NYFFW(VP%@'$@^Z V+:[6I:"Z&,3+Z3PK
M4:+?>%'A+VV7[=VAO**_7%9XK;OST5$WP*$)-W,4)R7,BF#X.@;MD*<J;O9>
M/&$%(%["P?2TW\*BBA][/X>X9T6*NCN_0;D,0X-+?8-*"N,&%?6=N0MVB&'%
MS]HV<X7[X@83EN9Z41 >W)7=9#VVT(H33=>8^!OA;TT^L'KL]ROO^0$H'6%.
MXXQWZG8S-M/V3MUINIK&<7XL\NOF1*;H]FP7@O=QE7LPBGMSK Z@6T=KD T^
M^#H"''+F(]M=;X_1UIOLK'K0BFG-]7)PG>K2&2'>JNQ1R_E[']@ <_<DL$((
M!AL,R!1AE\@]6D$:D;G_8U=AI$]L/J*+]&4Q[^M6"I#22E5'!MKHI,&GN*NL
M'D?8",-2<<A.)SA;[J+VX-_'[?H!DSKWN[PLRRU.+O/.+:6ZF?:H(KPN?>QA
M7&_E8X1^<.]U &AI?.-Z=<(ESU7@Q]'*(@.0<[\S[X:D,6Y2,^RU,1 /1$0E
M: WI>K(0":8"*"VB19U#P2>[!!E(3&*/5Z4)%JEMPJ7CY'J<[W,I(Q#GW,W3
M$-%> $1V.J.65UAX*A<I8HR34D3V99?&P;E[4V-C,Q7FUUEZYB5[12;*;K8/
M61I?+VEL2F<GFEH:H>^3LZ/-ZO+561D,5\<BEL9I7#4LG6G.27T[BUZC%>U3
MO%=T(;.NILS$<-'R-A]U-Z&=G=I5@E-H'$[IZ<96D1]NUK@[4+,3I3.G=AP^
M1@\+@31(JPT<,TKW2PC.VX-@CYBGG(ASPW,=MZ=?N"A(K\\I3Q18I?T=A;="
MWAULUXH&IX\;/FD*0A5X/O[ TT5<:2Z., ]ZO5RL".9[%09^:"3]<<,(=<<+
MI1@03IBPJ::DXE[51GQ>*M2/68EEF&L:V*VB"B?W17./G,H@NXXW>KC";XEB
M4X!!&4>40_+\TMQ'(0[PH*+11%71WN,7/G)B(Z%8\3O;LBF$N/A&&/L1?^$_
MZ?8&7)6]1DJC#.I%2$Z:P3FY%UQ]1%2S,^4%G<Q[VJR_SJSH2G24IN%=Q-^+
M5&[!CBO WS[W/H;M=K[': ?GW]Z0I<DE*1"385G_:8SR(25A.DS56LPU$=,4
M]AA]I7LGU$4Q]!J:VA#;XEE?*SA!1T-5$+.SPI'6JHC."YK%7<S5YSK5MGO6
MM%[D.Z6SUK1:RT=-'.3]G7%S@+T[ZF80#DX@5X3*AW'::\C8!>.IT.3+#D)U
M)LY<YC$[5Y&<U]<'JBR29;QQ0P>OY<-0  8'-*@4F1M<;+++&^>*ZCF?]PSJ
MA[H 8GJU.0XA?5\Q.-?V0>L<T$^RO#DK(7E^U!Y54NM!(6+/#%<2<J6C(& 7
MJ72>DB^*=<A'\#I*<Q0]16G&\M>"\Z]-W&W?P]%4@4K0:\*C%F@OY5&2 L,A
M+;0A:5I!4.\+W= !/"WR[NLSNH%2+>IU"F< VYNT*>3 $,8 ;DB9G@Q;%?C^
MS=MO/_]ADG=\9G\VHG,<I?SP(EV<O&A?T- YY^G*A_2(Q.AJ&?.6A'/A8'K#
MU!:9CBIS[5<?I'>&4?<CZ.&E)UA_"/$O@3G+;*TL75U=60XZ3U%P^/>W]ZD(
M^XO<8TJ%T\&F,D7J60Z]R=*9KJ8[?AVN1]7OW?R"2_8,0,X73V*^-\#^U'D"
M34Q9IVZFT9\_BMZY9Z5.TH='?OOX>_I^!NM79&"^U3=[[0R> CE_QB1.V<Y@
M&FMCW,"@OBY?X-( ?CV$"='?D=]PJ(:A-VED$!<*[CV:%TVIE;?,EN[3IC]'
M%;LO^>4LJG3]W%W=9X\<:U2W[[CJ@F'Y2, R'S<I>4%,(C@9KY?+$E=L*5$\
M'F):1='(>EWB-<'MK?*J!,$0R(1.6NMM99$0!K-P,+3"MAY@D _)(>/L72L,
MEDNVN;:"3U_3W-G7)/G(9\->IKUAY[<;D=-;1:2ZFC%D'3^GK9\</D$=5?2
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MB'"=[F=/\CL.7D$]Y?)U<]#)](/.N1PW3_\>3E-\30R?HUZF.$]QW+T UEF
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M6#;(U>WN-(-3<2^XXQE8EX%H(=^NP]^7KPF%^'GJ1?+?V[+BYZO'!5*R-H!
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M,AY3&E^,3WKO:V27WV/+ ..$]P0^I/89IOR-2MV68*#;K/77,M5W%X7/3-<
MDG*]1++Y;[1QHFU6(>ZLC,N^,U;K51H]T%E(E:I31#H_ ZI@%:IA+7=D0KUY
MR,ZK/A99@DDI7H54U; L]?OW8"K: $[*^>(_GZ!%59'T85OQ%W&K MU$[(AZ
M>';3B8];@]AT8/8#,U1#Y^ !C! /U$CM.E^]\&'>K6F$ #6#'IM^2;,1#5WG
MN_<,C+6^$X-8[PIT^IJODT^^9>+&0ZZSK?ZSLXT7:4Z#J1UGY*5^E12 RG<
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M#7 @ @X %0GB^=0("AQW0;391-D#(K</C.GX*DW$NU:,/J730-D/*AK,)$X
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M-[9Q?."$/;*%8)V_ZGVU:MP^ZYURYB.A!^6;F557J&9T80\(\WT_X.W]-.*
MYWZ;7^2%5*8<.?62YK.ZQ5>RC#ZGUJG+YWZX2'8=L&_L^TFEQC>Z7* 3N,:
M#(?!OL>WL\A-R^(D5.<*:!!9:#P0=D3 (-+5X32I'0RO+W@>1%\ET84_PO<G
M?*1%-A1V M*.*:/$HY9>:,=J3LLUC1Y]CU?;_QP3[V)_F[KD;_QEA3A:7$^
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ML"+XMO3L\W:+H&>-KV+OB%$532*#B2K:/'(-OJ."=0:%1N<9+""/1;\A?)_
M?E\X/E,GN"-T<ZC1M+&)P3Y;CAU=T$-BT]#6[R"MY?NK.3>W-WWZ6F'VM%&V
M&.1/B.KN0@;_&K8#9^R93X7Y-!2JAP%)WLI"CW7N2]?W5F!N&#G.($#P?7N
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M6_ <@W-*>,8B86J7W"@?-!_AT\BSQQ"GR]$$-(TEHXMKMXW3G>>,T(V-G&7
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M@+^NY][&+GSM!:AB==TWJ?IRFS3%T?%:VQ==2=Y#;3CVA?S* & >AY:IF[Z
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M+$60L$*88L(N7(D>&V\?+6:OOM FY]4F"W3*.SJME4I:H%/>T2E_>JU$)Z"
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M22>=^LWHP7/V;^KFTIC2! "V/AX?E:L'U:.]ZMX<" 3_YSZ%6KS.D6S351'
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M>3J'^S^M=M/FMUO%3U NA+AF"&M]U;"FQ<:]A*WV#SC,7_$L6_(H+^@D)P3
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M45.RTULP(F>:#@P*BQ9R(P(0"0Q:Z^WXU^&G#-"KG/F%-P!Z#-.Y2JZ&?1K
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MRZ#P1 (7[C$F471,0UA*O>]HU:#1 &:*ODX,1"4-)-W$\5A'NM8QIVR*##?
M8&X4^6S? HF2G"(<5^.!(&8;JB_?/P&U2SEA_S6]QNXM63O/+4?SOYD7WX;V
M@7U =WNWNKM;^_;OT7ZS]7C7^F7OIA;>Z'.*((:5I"]D;+"MQ'UOB([P<,=W
MR[NUY!VW@X'A^ ;735 @MIC\Q?MYJWP 7!76 E/ ;]@8FL:BWN,'!X?JHBMH
MU$UG0 ,MA$Z(RFBYCL[AOXXJ^X<HJC+JDEUB':XD6MUR//P]?#;[ &C+\1@]
M*B@%OUQI+ASN;JW$<(F5I5P2^D]MKU*?(/ZLD(Z,!P;C1HCZFH3*U%Z<.8%/
MSC+<,JQA2'63)J,ME8#AA/'Q_4O> C2JPO[C>>KD!<9&AB=C@3+)ID^B9!Z5
M]Q+MW&\BR!"E"9EKM?K>MW\;HZOF[U?U7^[WYT#F:>-.P.Y:K5S?FQ.[+Z[/
M8TBM&M$?U4O5HX/2?E12> R]I;$1B4S\##2/2C!=@S)&)U7?6R8^KA@)%ZPL
M='9S^O6J>=UNL8MK;*MU<]=H-\_8I[_87?.\>8?]MM8Q%"+<5JP8]<KGMJA!
M9[ZLS/I[=C,DJ\D)CBD-_>_9[\C;X>N<)VW&5J;6])YA1^L3=ND\<)>VZ#W#
M>G)B[=<.KL@T$\F6ZE7\:LWR0)^!%4L9;?EX^_SR;NW&I\LF-BH]O;EN(U&:
ML];;TB#-Z/CXU(R"&;#,'VV%RO&TC"AX'2YQSW5@(W$(!R15M]?9KE?W2O7=
MHU)]?W\G(UE, G!,-68UUG>1=_ZG]@W4T&7JP[>-NS:[",]1FZ#T3TXJK#VC
M".Y!AE;ZE.W\HV_Z/+:'J0VK+]6^U&Y>L5J%??K:NKANMEJ+;]VK;]<4[$OM
MW.[R=ZY187<7K5_9>>.T?7/WDMNW6W\9=-M;_J9]JK"OUW?-ULWE[R#\M=J-
M<Z3!5U<)&OP""%A]<0S<7_IFUBOL]N[FMGF'+;C7<?-FH-_!TG=LM\(NFY\;
ME[AOI\WFV<7UY[7<N/FQ[G#I>[A785? +UBK<=YL_\7.+EJGES>MKW<OBX*U
MET'!H^5+*$\045Y_F^80\[)C Q*[>;QT9-P'9&S<_=ILL_.;.W;7_'S1:M\U
MKMO2A-4BWG)SS9J_?;UH_U6")R[)ZM!JWYS^^N7F\JQY!P.TV\V[%FM<G[&+
M5NLK?'3[]>[T2Z/5;*&*(-YEK>;IU[N+ER:UJ\+S^4^M5EWZJ1W"GE\W/C>1
MZX<GA83D:ZMU :>%)P$/7/[5NJ 3.+^X;ER?7@#=!G7M#,Y /@,TY^MEFQY!
M-MC +];Q<.8FY[6E:DSB+!KLMZ]P8R[:L'V_-VE?X8-+]7>,OK/&IYNO;77A
M4/9]R<T^?!&*7UN^BG54B2$P2+SMIC"#XDZWOM[>7M+?C3O@I8UVXP6W]+R<
M*_906[Z.=EQA0,>O/S?1Z$P;#NC<^'S7E$?PQT7["VN<GMY\A0/ #Y"PB#]!
M-*07HJ.3?.(E<?[X97!^^7K>,2C':%J[N[D4B$X"]]E+2XG+VK_Y"?3RM;SC
M3^RF_06$DHMKD'&N7IK)':Y*V5N ,"Q?$3P^C3$VE!L;=Z@,HA39O/A\S7X!
M4:]U=G&*F]UB[2^--F!P\W<@&G ,K=NF^&(=CV%^5%ZJZBAUGY=4?E:&N:E]
M6JJ.**QD5<#.NR:9%4NL^2=H'B2+W9R?7YPJ527TH;+/-[\W[Y!+-==Q=^='
MR.6KC[5:);:]H"O>-J];+TYA]UZ=PM:7K^/5ZA6E,O_%;OZX!K3]<G%++K?F
M7;L!XMBGYG43\!E%*_$]H76D&4H5;Z+"7GG!,SI:EL5]*K8O+^M) KN\ 1/8
M4E-GO%L)3Y,."IDBG'(K<71HD&DU!,<L22%<$#?@I6=-N')G(OA#2^0LK?(T
M7\9=5U^!NVX/;?X7H)#<PK6)J2KGS:;4*)MWOP.3>$G99&G;.3<KJ"]5512R
MR>\ON6-'+X. *W#@[2/'_'+QZ:(-ESG#KL%:IU] T;M\60Q<UG[.CX'+5_1J
M!Q74/U#\*__*6E^OKAIW?[WD)D[0EF/!]>F0F(YC&4^,BY$;_I^[!_OGQ[77
MBV[;??N!;$4DVXM$LH67X;F!GA_,C^>.^Z"Y!ARL\QT#A5MAHBI(O>;$92T-
MA%7'[(43M;&\?L.V QCJ+BQ; \L?"#(HJSUXFQM=L25E2VY)E+M;80TK63E"
MYL81%8S7DX#)?,=%/L"ZFNY[%!&NJ=PX?SHLI<T- 4UR=@R<![@HI#[ O&/@
M,^90E(D-_,#%) 63>A=0^+<K&@XX[@AS'CC 8W-L:0 CE=0+44V*H2-*:I7"
M3)/-#0S2]WEO)-H$6!IF,V-<.35",N]%O'Y4X8?*<,F!G2$7P9 P%V9 3]O3
M=I^S!P>K:LG*V!UNF0"HJKZ]N2$_'VBC=$5N6)8Y@*'2G^-VFW8P]GFT:>EO
ML,R0;8R-_SB$M8Y!XO6=P!I[& F8KGE^^O.AXV-^MF:-?>%RP]3'GM>S!G_
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M"ZFFD&H*J>;5?O+!*T0/IURPBIR@B,L]CB7X\P!+3K1Q ^0\RQEB='4>P,'
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M!0<S?0:KQUT".<DS4;,!P AV@$X3!0T1)0 ##1-6I5E68OP2O.RB80N!!Y3
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MS0WB$SK042"0PO$A]K(%^PA/&&CP0WLZS(B20GQ8=HL>?3@'UI1)#9L;;6>
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M+)X4-X<)V8G87>(X17=<:5;&AI51'2*0+2E0B-I52MABW550QQ@H,#L<A<C
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M5E/ZS,Q3X'ALS;+RK:HZK!2E*?UBLKO$S-GP*=K<C/X,FQLS&C3$RT#,;M>
M30VF-F@(/2XE)K<!BV*1)[D;8")45!)<)!&02PM+\86Q&VT1RG0#,U-NO^KT
M.Z$+&!;M6_,+N-I"VA,*:%-F*M!6M!**DAI>44I[0BEMM.$FR5Y12'O"#-/L
MG+7RWO+LG*]HTL1U")M>V!%0M'*H #]*Y]6I[M.IJ)=T$J@PA"&--2N\4E(2
MDD?>'BX]113O%$DFCJP%#/++CNHP(F)S([,0Q<T!#\5\S@$EY/JF'EC!H)2N
MZHN&KC$Q3_;UU@9D(B/MB$0KCR!"FY7@JLGT7N&+2N1(3[I\M)>RVT)F@JJN
M84 3+^]2)40I%)*PBJ(<'@)VY%7R7%B;>'-C6]*;@2Q+K#9*I'V*A%&QK?*R
MA4$;@5<*X]A#WPE&<8AY9:X[[$<4< ZR;62K%'FC5"4#DXA%5T71Z8?*.XM0
MA+A!#]Y2IC_AU0L[QDRSBZ\YV[M=2#>9:#4@#'HQC0,CSZ='&A0:QS-<8;7J
MP<&;=87AXK U^\!\Y&%#H'?BW_KFAJ@L7TJ4PXIBG$*\CDM-@HMH&.1-*'-O
M>CH7U3)->Z)G!.$@;2M**/ ?G*0\$R4Y3YTC75T\]+* J _B&?GW: + :R]L
M;2:+LU(O>"S&)HUV?P<8/!9ZTN,3#T6) Y5=3!K W!8Y6F^RD N%%\I@/3+F
M.+J)E2HH?A=K?WE]K,"KR@T0Q:"2NP]CL7E(!"Q*/KI7A5-(0T6EDO9)J7;X
M<F"+]&^CPIHJ(!Y/PM6&TE_F\H%F4AYL7%P@/'AP6-\)5"V-*.0@<2*EV.Y:
M]&]_-$0ESJ8H.71)X80JDI+"0OZ6#BGD+#'G&\7R47T0(#R &\)U+R.H:73A
MS'O&J8 X$KCV^"&P\ S(O"55?K7CHL!8XD QW &H9T7J-!1-*H+"%?:E QC@
MR- [1&L>Q1L)R]/MD54/52,LCB"RHS7<Q*G*!*U*[$I7NW>$KU>:(J3N)<#O
M:+Z/+MID<6M5S6S="?P\WKR]PINWF#=OO_#F%=Z\%^D,.T4^VSUD;UA @]6E
MQ"^A4">D+FR6'I8G!6:#?B$,)M'1<N92[2.R#F Y%MF&2<,B^&:O[Y,G!T:D
MYU5A1MG&%<4'BLL+2V_1_&%0B,]LS79@1,U5G#"K()>H<"_%REB#(G*<.H89
M#*@&C4WO^QC0XR8&E;J\ZC(0,VA@52OBJ25I%%,+"$T<F(-$(8B1Q$K[T5?M
M9Z, +"I92>U7A;CXW00=732$$ALIM7/EDQ-"&!5P$ASZG1*LQ'-A7)'OI,(-
M,1^,TBL%9#)X$KBP.1@$-@H1Z!4F(0*[)*B(KA9]AL/$>X-Z=$06GJ5 #=&C
M2 ;[4%@DJ?VR3Q1%-F,1TN3DPL],G9?"/8A9*2B 2Q,V>/$>?8==V537K>A@
M049SN8!JI(PG0NB.2FG&!L$<;<ST,$7M)FS7$FMO%5JT;.-=#(O4:G22#Y-P
MP_S*ZI*J\J9L&+'9!WS0 3$*K9Z."V.J] ^Q(2@PB[ N(611%HC$57)-*1,M
M!7LG&YN!YA#&^./18@H@A05(Q5LFJ"@9/>Q/178 [H.T1[;:;0\V4%,=SQ*8
M*)/&4=#%1EPRPQ3QC2+$L.I<*MH6 [CMGAFU\,KT3W<L] ?=(S26)PQ4L1U+
MA&FON5PX@^[&6PG*RQ4WIU*\7*IFF6P.2$W0(E.)<(KX5(,+QK4=U@LT"KW@
MX1U5AKE1JL2 G2)Y4A-^0/+4D67"R&-'I$J"L>;G\D=4[H"J0(H\9!4.(^K!
MH?%)#\@N"W>-KF=DE9!-<J6)@!S(KJZ*1]A4/= !PNKY49 JE@^4SB9'=#Q$
M:ZTT,JM8"Z"<^G=4 ^$2HKN'5YA*^*!B=7CE-?V?P'1YK"\>W2I1^ /F"H3;
M"]L+BQ5I'O(';/X'PB0&5ZADW@>3*NN"E@?WC:#*'@2+E LH-C?PJ9ZCK7W.
M:=3JM"TJAEQ$J;=OH^DIEM9UPWQ6$;NLFN0ET1DY6MB24-6E[KB.!JB-: [T
M7WI#5/]2E9;-$AU.0^?_FG?1.Y691]<R\Z@E,H_^?_;>M#EN(VL3_<X(_@=,
M3\^$'+=(BUIMJZ\C:"UM3;=MC:3N?F.^W,A"956AA0*JL9 J__I[MMQ0*)*2
M)652@WKC;8LD"CC(Y>19GO,<Z>_0?K'<^$UO^\6:8,LO"PI!P46G#XO*<\V<
MJ^R[QD/7>5^FIZ!4"M! (-7,_##+?JFK&N^C!\XO/J@Q=[G )NIP;AE!P?+\
MDW& G4,MW[_WW?;]DPP??+)4FZ+<_7#=<* %>K(F3P8[#SW\'Y]JAL!S/RCE
M@YA2?O_H\?=7BSFZ+N*(.U+ @,*:6A4#I0$C_=[=>Y)1M;1,CTX?(S5BB3KO
M?(/E!7 0,ACWT4.I9,1S6%'_5O0LJ!@;C>+#G"PL %'Q[UUSWK9USI0S>R:A
ME:OU#+:JPF.8@9?&>,Z5P6R-0BK%,J=1$" *H2?A+/\WQ_0Q44B8,W2%[MU]
M>/<T^T4[U@FASB6@"XA1+]2.HP%,J4H4E;L-N#^;JREA60;N@08&J21-Z+5<
MI0@YBM22#>R2#NT2QG,Q/1"Q5P<X%1X8-G)A+OMF91JC<.<3;'A"T0#,.(L$
M(YTY<FS)NQRK"')4V*X.E>ZG.R*,YS>GZ(=KMW/J;Q>*QX&*DHC<']3"]'_W
M*3IYO3H^.?N.(I:?\@B95/JDTK^HN"/=7\94^F$B(0I%6A7BP.@F3C$H)R=%
MQX7&#0)9VIEK)XEACP5B:)TR:\L:%C1R^""Q%0;/F,K'1D%%QQORQ!"]))$2
MU5*^K5HA%#@ W' FS03H<M,:DI\O7"IP2A&Y&:)2MU1R<GK%<'@QA@$GH5HN
MP>;OF/>(&"G/[MH#<:MK9"!PQ(0L0K?;FJ8AQ6)1ZA,Z+HGO#,]*^#U_47B$
M#THEQPN*]'YKSR70J/DZ^_/9V>G#;"Z"T"%U[WLS!7E>,X<-7/[7LIZK\IGJ
MU =JX'N3!IXT<!H:^,<Q\^!;2<G'\269YS*3CVVK:#1OV&S143G\UPF,V#N/
M^C7@]21#<(CM$D)(-.N4X!%0%5ZJG7N^TXWR]8#,7HJ4.8B5-\76+X!'V4K0
MDZ*A"*#,.&=$KS#^FP(:=$8T_=;RKG'!% 9&C!AK>-F:0^9&U2.:!S0CW9Z&
M8!8<.^-P-GYEBOFU5';%9X_%E&SZ3GDU?4X ;O^+8WN:_:3IF[  2IA(,JR5
ME_Q 0,RFIBX'>;V9&V89\ER6FKZ$;4-V".6IG5UNYDT::(L@3@*<9(L,XOE0
MU.X$Y@$SZLAMW!H Z0;D0<L=4^Z@RQMD[Z#"#R:U)/J^?'>:88L^D8FD88(,
M;2Z8N<>'ZVXX@1Y3P,RESF 2Z'&:V &XR;1M$[<NRH4]F##E\,3<3*:KT9UJ
MF#QM%BS(H@F<F*U6[V#-J?(=GX0*LYZEUEM9H:"_L0.I)7&CB[!^8. -(4R!
M ,&PRK!K5_#&WCR81A!AYSD:7'K/L[M(+'UR]I#XI65T0UR]N=?GU#Y?\D'C
M![]_]-\ 2.^#^F\"Z'DX 7H^#-#S: +T?%Y S\<M\L#(_%QC$D[/W;W)N4N#
M=HT%.F+7W3M]2+-*0[?WYS]HC^_9;5?[S!_])&%8=.HRYN>_TA!#[,TTA)DF
M:/^S;YG$_-QY\5]OODE#E*)-0X[ ?XCY02!$&I)@Y1WUP$M#'$M_&%L0_"!.
M*PU)D#,GM@SX\=$P:4BT*%IQ&-.0A^K"8PN!']5W19O(\J4P0],G(HT).LW2
M$(?).HHRE07L4-:Q1<$/1N5.TQ#E/!$KACMPQ98"/^F8,6,$[;%EPH_M(I"(
ML@&?( U!4G$)7,XB#7E4&F)8CH,TQ$G%_F42OE3\$T_?I2%0,L:O(8=.Q')X
MFTK<(8 BQOZL52)G0"(ZMT%>B#1$247?NB*LV)+@1^B)&!><ADA,?Y&,MY:*
MO9!,H->4!:4A35+15>;!260?.91J&O*DX^.K1+:TM$[2[[?(P<,(VGNI9$-3
M.2^3T7LO?GE]EH8D!!!,0Y3)#1C[)!,)\ONLI2'2/)&<@&GLE(8T12(G$G).
MG\!Z222M98K7TXG:)1,.,ECU9&Q?)&/N<$OM$CF:DLD+)!,40IZJ-"19Z(Y*
M#-*0)A7MJ\I4HD+U5JC6$UFYR:A=W:VK5#0N=M38IH(D>*W!_F[RM6X263*+
M.@TYJCJ13-:[JKY,0Y)D7'K]'KRC-$0QG==BRX$?8NB,+01^UJFL6.P[GH8D
MEL0F#7&H.5 :HF"-:QJ28%>P-"39+_"-^0&/+!%KY0U3_J8AC"'L2$,:[DL3
M6PK\)&,F)!5;5J:E?&Q!\!.4IZ<ATMD/#[ D/@UAJ"H_#5&2<:'/?GA$U 7?
MI3--ACXA#6G^->!CBOU![J@T).G6J:3NSV8/[MY-9P$S(5<:LB3D$LP3&1+#
MJ).&-*FD8-$=V"?W"J@Q)G*TKX0<[5HI$V*G/+ F/V*!I")_,H+=*I;29]KT
M[&4I#3F>^STSXVW4O[&O";&U8=^5NID3HZ@CU@PI+9'^BVR\[&=J]I/]YC6-
M85+-%;%>4N>A!3]-F8(8ZA#CJ#4#SF?AUKQWEOWD,VO>OQL*< Y_@R_\PC<Q
MF9O3[-5:-1O0C'TG7<%-?Z@EM:$(1P.['U'CHW6!/2>%,711;Y"*C@GOYF6=
MOYO#)((2Q@8YB_8T^[F^1 (S;D;,5U.W#.9K*Z5+#5^-[W>IN!EQB0T<\ &]
MG.E(;EJYIAK2U=+Q:)-K>H%]QZE3>3"2-(@3I?-T9B9]9MXJ9?E\6Y1ZV^Y"
M56E^RXH26^A0\RONY1IPAUK:S "SB%JDT4)OG/45;ND:^4<-SR*I2^RI(S_S
MXY'%DAN;XM>P,4YKFW]YO/9JSN2$LTR_SX71DRZI2$0DD#8DH:ZQDB@:HBL]
MS<X'BIV?_Y3HWUCS2$,1V$S<[A6)(5]Q;WBB,2VP;\'9PTR;H;+TF_=/'^SW
M+H 71KK^F;N>VFUWH(BEH6RI%Q(XF/<=L?(C%?YBQES5&]L&@#E9B:&4V[_@
M>(-2YX8(,'Q<+2O'T D_#[E#27E*IQ@LJLT\]NOP4G=BM8[0U']1Y*9NI?$"
M#EC0WPT)_V9>+P#'_,\2]-(1SN<_I7>D5O3>"\BB^-BWF$Z+X+0(^/Y(V;2P
M=/CQTY$P'0E6W%]=KW,6\Q4R/)NCX5^:,-@5DRBK<E4H:EHVTB&]]=JR4^>[
M#@Z%TE+<HV:VW/MTI6DC*3T.#;X/>V)C[S:_F^%I]JMY/-Z;>/)1!14Y4DBC
M4J>^*$2=3VS+U'R%&T[:Y\U%M15@6=;:2-AN4:U@AQ%KL0H9+GW):6)L?XE%
M==0KVW5ID0[T.3Z5Y+(-N?!.5FKJ"F@I^Y?POW!0,N>V-KI=CF7J"BF]*MN.
M2*9^Q[.+=>&>F9R:SON$3<$^2N5^B@?_Z<>GU'[S$]WL4[8!&W;\FDZ8Z81)
M^X3YA<2PH9%?X%"HX#K70 ;L7@XQ8&\4E;7O"M.(>8:Y6?XRZ$3Y'G8"IG;+
M=9Y3HTSY4[[#GEU+:@MM[/\:%+OIR,J/USM]FOVR?U>,O?2@33D0P9$,#AJA
M/P$ZV1.+6R6S6^,%8+@9@D93N6%_"?O87,!__=XQU& 7SLO%O_L+E,!^?P9>
M%5S/+0FP/S0=8FJ[HQ,7#67C$=!O!VY-P6&J'+RJ<["F=RW<[V65GW(?!Q/C
M8A%&!G6\#0SVC,;__OGQ?A^8Q(Z=21%.BC!Q1?BJH5HP$WY@56*TX!O/; 1M
M0!U,Z&JC<\BY1F98KSLX&=NF&XM1>N:+H&.R5:F<-D3X!*@D^/NBE_[I* BW
MWSHU K$UCNV-;6_RW[7K0&[%,LW'L[W>XS/Z54&=NZ11X;RNI-U&N=MLUV!B
M+RR2XQG&REFI45";5?#P]3%:Y*LF&U,F,YL>].>SNZ=GOIJB%A[8BG$Y$E_G
MP#J+8*+KV8N^ZQL]J;9)M4VJ[<-Z!=)VM-'$@7)S?PZTF;-#*H3&J'9CU,B6
MOX =GEAW_:,J<.._096 ?86"CCN/[E%_'=N4U?K1V[WG7H)V '<] V-J5=48
MF^S6(,L.MC^WI@IN_)#00W";#F/4+7\;VRGY':Q8Y**Q-JM5,S:B@&]@@L-F
M;-[4>:$[,./>4,LE<.<71<XQ!5!=DO;#EGK8F4G#>W7F&M>75JPVU)>=2TAN
M@PRA"&&MU,/#XJO4/]\_?3RP^!Y_1K5X*WMPW[ YT:.I.=&'-2=Z/#4G^KS-
MB3[#!O@,]_Z$@<1#TL]__$OQX]-ZL]4=9:'^\FT!KS2/_%J?J!L;!B<(A[(H
MVKSFOGMA[T?0^ NX&@//< ;2%;D9C L]&\GRJFT!9^3B D\-:O%'OH7.UQ7F
MB'?8[Q$3@=0,,K?1_J;>-@6V\-L-OHM]<%LB#RG!&3C'R#\[)W@N+8J%Z\)^
MJ<DE:?L<<\!8N[4S;T)OA5EKW6!T'F2=T;7\*IJSC?I]T5(?0G8T"AQ'RF-<
MNM\<']&C\+L2T%<7JBA)#X@+M63_(/NM;[Q'9O5V6S==#S8*W(:QM6ADP''=
MYS!R\"!=%@9S4RRSFK].(UTWK7F3XZ.]5S$#(L. 7A!E&32SY>,L409BJ2^Q
M*SK"F/A/:"29B_.ZNM 5I=EK]J3 XN!(3T7Y=$J<4/5D^#@9=1'O] LLVB^V
M.[QN]C@;9/<A+DNL-6LO'1_!"KZB.SVZE^0&/_WUC?EM*_GQEMWFX6R?T&_
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MSFU.IMQ]S'N'VPM&P;PW0B V5:&X>OL]XKZO?>_KE&!VO0Z\Z;Y\ YI1;^2
M^^Z3+AE$%MYX[)1GZSOK%387F(QYMMYA<D<D8._EILN&\(TWC&E^^&O?9-D<
M'UWS[@,',5! ,!QW3K[)-)9*(/[CN@#]P2U#&_-3A@%O=W0K,,@NZU$734Y
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M64K[)QN,[Z4SJ[E%T;&:MS$%SJEE&.ZPE1F((*DJ@@OQ7%'\3K5,_6/B@HU
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M37BV!\&QP>GN,XQ:-J-]DGZO,<)XJP=K09GW=;T!AO:E3W/R1UH^J- LX:#
M:->'H+A4XDC#+A"NV\ 5;^^T3&L \P1J?&OB$H?Z17R"_A AZ3>MC@-Q!E=A
M[C=.L$TCPC83G[B+1'!<%M1IZ..Z2 @I!*K]IA&<JZ_?A;[$NL]RS"UJZO.%
MU<QSU4@WA"LZ4I#LRT*<P*NZ4]QN&^=&.=1[4P[UPW*H]Z<<ZI1#_1(YU+\4
M/SY_CYD'BO<-NG>)IVO"W2#!K8_@F* L@_R76'>*!\,[RSI5L-F*+RQYH,*K
M?^ ^ZC1<G-XA-*/E&/)()WCL3&C"]P(-JR92X]@*/@'U8'V?8!/+<C=S9"8<
M  #S=D6&%.&MQX5G@K+='@4?L2UYM9U7$+T&[(]L!P_9%;9U)Z3%9/,0J HL
MV8WN,M/XDQ-X)JT[3L#Z+PF!(?47WLA_*1FN :>3P01[@PRO9 Q;%YJG=B9-
M79)#P 7%7N[0L9EXB#Z_+&%FB-YL3M!#4;?Y&OP"F8:P0L.(,"*2BQ 27Q!'
MX1GN/_8"/.H&7BMKD6YMGDX%WH:<PH$439YB2^40U<Z%C6P!%;/>[$LMU10Z
M@-'^>NL9;S .8TW/L>(7/QD[\]O!.Z]( J/CFV[FLE[SP2X=./D26^#TX:A:
M\90P;SU>Y"[B24111;<+ I&P#I",56HY."AYRR?-AUT$0SH< "3E+O;T]%#?
M6:TC01(7807GB'PJ2P 6 %W!J\&K-M(+)@ M<!#+%,43 ZPD__W6HB[E%*0$
M%:S"S;9SH14_(&U;()IEZF5!K?]VL"C%HU <'3#FFUTNT5W#Z'9XC UKF'!(
MU85 I,RB\YQ+ Q[EAZ!71)=X^\.6;+7%>U-#9E4.:>@%$[JV(<. 5WOGM#U\
MD>!.7*I"+)0"N*""/OM\K."[[=Y52* T9%7W=P7HBC$=0/6/8QOC!F; D 5Z
MY*F^XC&U0%BINZ7CUQQ?D@<V!YAYBS4#T%U/1>4QD(.XQ/N9&1N,(4QPU.VH
MWWBY$^;K!2(^?,Y;(10FOSML:A;>$PO]D04.[DOQ>*3P+TP=7@$K"J,Q]**;
MNID7BX*W_0;I,THJ2#TH&FD"*YO_BC>XKTLK6\'M*W5<U$3D\TA0UE=B$^!-
M2:9&T7\)M8]!1E5JH;QDN\>06]J2!N9D*,R3R?.F8DN,6W(0RQ)U8AK_($=F
MD 'UV[^R&G;HB0 01*?LR,HUM#*NZH?JCL'W/)%.UB6JUBL!,4CY0,O_FD?)
MPO8R*]KZ1%[<;&O;;0V,0P?S,D ='RM&'2-\*5W_.E,M8,!_JB![&N=2T/ZR
MB'PF#ED,XP@F[_PQ*%?8E^&<#?:M'P/5+G7/$2P;X#:M4 >8*XE9,K&,DC?O
MBHU77^ @&\='I>HK^.Y719M*QR1R .("93*$$&[ZQB:^CH]>5A6,+OW:!RC#
MS+UY:2'*+IM+ %PL75K5G#=8R'H>X^6E6(_7"KU1VT*WEJ:7LBI#'4XG.@'S
MLI&O[_Q#'+&F =^XUN]HR?G>)]-T6_;VUI6(^[<GEP[O;X0KPER"9\HQ58:6
M=!'WP#$%6&!U^(5XIA$K6UNS&SJ]8#*-N*:&E\"6H;M#Y(*IDL:JROSSV?>8
M?18+WY[$ #46\1:6;9'G+*/TV7Z)(9*W>J:I.<^\QBQ!9VW+KVRZ1]1SXEE8
MV'8UWK$Y9*D-@PH6&^<PR:&KCAX-^):48VUG?O:'WH"FL\5E1B7"&-@32BD<
M:$2P(4H %#8^^;J5R$74"QHU=.FP!;D0'LQK=-/&E!M/:& (6U6F*N.\'1\9
M^+1/UL6XZ*4#H+L6B@U:$!TA"96_?CT3'%F 1MYH4+I[63?(W<4UW>0)<F7:
M:$C.U$\3BO%VJ\\7!SSJ$3<7;+OK5L:BIJ0QPWQX BVJ*H!<8XDY;M.#H^U?
M+($]6)ZVTY*6:C\WZ89_GQ\4*"8#>S2>?P@6*QFB-:@ -+>MZ@RY@I"M5>NN
M-3!(:Y7CP^31+DT[O!GE1!G80U_P<$S^>_HUK>T:#%+LOGW+U]>-$E3WIP35
MAR6H'DP)JBE!]8425+\U6W3)@\@6ZKG;GXURG%7RCNP^Y%UX0)!)@AX]CX,W
M!)0S8>MD)/394+W'B'7K432JT0O$:Q>S<:DOF3\,GG[O[MW9W;MWR?H%2[CG
M7G@D[C\J\IC?=&048Y>9 IL@VMML./OR 3>A86@TXZ$QI"!Q%H8AYMT@L)1C
M8:9KN&! A,($HT(LIB.C'!6?4SL%=4;07@<["JRX<3*H3,0:8O_$!9NAK2H=
M*;LM.?IM?P(=?1.5A;D*MX <SU!E$6#:Y<-H7>!(#V\K?1.%.<TV#_<ZJ2!,
MERU*XJNPV3RY%_&\-8Z[TU*#NE9"U,QCY(TLA3H,T@7F(2OL\XA6,^JY@LP3
ML2W8YNH;ZSIRV,3#LQWDF;SE1DG@+=#ZQ6#HR 9'?XX;Q)844Y,:.I>L"S#"
M5R5;O9K6@A_''L1PU?A9%UP^)>L4ELV5ZTH[^0L*.@H%HU:5YPP;[142">W$
M30\2",0G1ZC!T.6R^57\C0,B"B$%F> [<&41D/:>$JF'F!Z]>@%<?)<2GG(L
M)#T9QXWP\/GCP&$&GAGOI4D/%)6)G-(;.$!_,)"5QR#G-9G8][)]KXX=4ID!
MY@QK^#G88*'B<!KR;1/O7&O?+VS!@^-$6B);]E+L6U^2,S0@&4+5B>I6O7>;
ME5&)F#0^66HMM=]>MUGLO;K9ZJX@4FW&FW(HR0\B+@I0_XW'T.0P 1ZT-"RX
MEN'V$P7>T%. ?,[HU+VE3TO%?!&=/,Z-.2D^\J%6U_F",-T61T+G90TN05#N
M0V3J='C4?6.C8H9_W*Y>/";]"SA\()G_A2V!-J5 'ONA&W]7M#FLIQ_L'<%1
MHGHPY6G*NX\,;!N\1+@I54M\.57 /11&HV%E4HYRH-!<+M15 ^^W(N,9JP):
MY:96"Y.:N92LB[LKL4<958/13=%;E(;9W[JW_.P B_A\/L>SD49TC((7;O;P
M[L,[\V_NW/OF^"C\ ^YI5_KHK^;;;T^_K"@JO;^:>.6:P)%PCI'V8"3W?GT5
M$MN'953,&*$ZKW$2UHI),I&:P7A0]<H5*)@J.;_.EXMIB1M^KRCY']N@)-8D
MS&8L@>UDTQ'H/23@'X(";.U=039#Q08=Y14,MY7?TNC<B$<+ZI6M7<>W?>M9
MCTBQ8C*+SRTP@8MR-G4%]J*MP$ )) /P6T-!N9_J^MVI"?Q3?N[X*'P+[T*,
MS<[H]WU#7*YPKG>L>?S#A\Y8IOT8=.V#0;]NMW"R])P@6K18[-[A%1NP?!D:
MUIP4*)\;CH0ENP._X6^U]0E&[/6"?]S"M[7F9@_?X'3X(W1\)$/$XV!Y=&7A
MR!\IZX-C?K)_&1& X2LXML]E4$SM\J[6W+1JG:EKT)PPW#4.3(9_=\3+!UAI
M/$Z&C).V?'>95M.5RA'BHPU6V?TH1 NDKN?4E%R;!68YP?U;$19$S@_+!,[A
M?^^KN65P..61&>QVUU(9CPV7K?72N'5CJOL#0GC+_1ZV%21&=FDD&)#?#!E.
M9 \7C>QK4Y2G9$L.F1 .O14GMWWR05J:EVHGW"L,E0R;:-(;N_&=V1)0LW?Q
M^6/I11HOV/SNNRZWN#='IM&A*5J#.7?C+<@+RE5A^03OYRTVR%4YW*,U[.W;
MQN?&-PU@C&*S&\]_[NT^P,Z=[AE"4Y6-1.!:YFPNYB<UL?J0>S!CX W1YP1'
MD7/*2>=P-W?K"]H_$CN)RF!8UZ1'K<(YS=Z0>^'[;-0C@\OT'*:2BGY=W;97
MY1:4,7I)6DYJP052E.8?1]P2T[;%0??H ".)(5:']=\LV%6R=_F5>W4J>PKP
MUF0O,&2^DK-U? XH5$.TYX.&YMR&VEG>XS11MWMAWBB+\F#*HGQ8%N7AE$69
MLBA?BBJ1;"!0<N/6;25(1M\*PIK(Y<XP$2!!DG2XPC#>P $QA[(],Q8#E0]G
ME*_;?6<@+'IA-"OY.G)O?M1L<*8QO:&1$;3P#]F=,WDI'W]G?#:?B1<-40X6
MH#U1@)7^)+,C0C98\&@)!FWQ=G#A?>\I^]?A?>5:"D!1BH!_P7A4*G7EUA\+
M VST&65:-(H1_$]UR')GN@$)_P0G\<Z#@S(0> IN52S 'JBD4I>V.-5ONPP_
M# @62;LXCNN<?"X#:P.N-JIKJYGLG<QM>'I*Y@X,YMY.>B!H:SD!*79I?LEU
M2R0_7A"\ =-RDU<%X_A*-6H%9NTZ>_G/4%Y+['7MFK>VCRFHONJV4HIT]4U=
M6FA(#LY-Q#P$U6 X*)Y@JM:]?43#3;:9+*L9@H0HWLVALMWP3C2JY(>C4+2#
MF7/!8WQFZ:A=&:TWLPBN&[);;LC<=&&LD0.#^M==N2+&=!)%[HEO$L:X8/#U
MX":_\A_^;NDG.Z_JR^B2NL3>%]C92[IJWF#AN99S5!DFBEF*+&"&*53[]N##
M*(I*WAI3DZ%V L/6*E#:Z%SUKR[;OC#<$LS(+N_AWAI_.OS>+(C(QA04AQ]D
MNS@\>,AO3=U^;,XPU^ EXH\W''+5@P6DC#N,?@IM'"H&H^Z;MA>$&7CT24T3
M0%,J $^Y?Y?%X3J5F:>GPTC=#%9$UY66'8#V/[_:+-O4"P??@EG"B'S?, ;-
M=C"QS%'!\& <*C.%"$LLTU&"Z[W19D8\/^9V^Y9RN[JL+V<W7&MP0.%"OTK5
M53N/N8-O@&QZ/"+\LQ^ /AP%W+,N) 0F]4[>\7S+U1-'YH.P/"U$:F$C)4_L
M)C\]QY8W%;>H9"_6J^<,R64=&9J7;+&NO*GT>NH%#Y$=^$*?8'[*X 9I<YG)
M<[>BL\@*ZR6G0CR%+$A.6CN%B0F:.1-4AT%;T_Z*R;6IJR&7\'24C#NW86W%
M1=*#*PRBW-1ZXP(=BT:XA+0U;"339CNYN@@I[--"NWQW(51[W,B-D2',4T7Z
MT-9(T1$1E-32<P2JC=&59XZM)IAY&O@0"^1GTPWS'NMZCH%8S(07\%BXE_//
M"E-\<.[U:9Q)H@*'WX5U>-V]D;I@%QZY8]']7KHIN)N[!ZJURK#!;K8X\&R]
M\.]N.O1<+%Y*%-5O92@+ M6D0*$.I4 E.FWCAX4495PX1D-?-)_"W751.A!<
M0]]%XF@EB%J.1-,H&E7R24*Q.NNIA"T]+-9X4.WIRI5,]S9R%):80Z:$,J5?
M"\O]W@J=DX<07KJCEBQMR:KC_@Y.%]R>E3Z0<PJR8V(]RE#B*. 28K/BENMD
MJQV]FKARYW0E%I-H,_(P5)O1[.K2;JP9YQ4,4;^TD+-5(-P.:<EZSR077#=M
M3K1Y*8-Y4?M%?,='TE)'ZA,O-:<"N$\L/=JRG<FDN:7,!-%Z$_85XK0,-O&R
ME ]#G,,@^3AC9:3?(YF?WF?G%/YNDD:22ZTH?CL.)HU0R CS8>0/*25=6W9T
M6!,O/)<U1'?X'.2>NRU19R:(D/>X8N ET:7-@<)L=W:@0M/Q^.B<"I5]*XI+
MEU$TSHP,--Y>$XG]9$<(Y0@J,<''.\U>V'.;*B8.#)VUVFYB/H QT'/OS5&E
M5%E6!>DK(!=S63T6Y :9=2^Y9H[^*Y2DQ5#JT<;*5U:'[G57J#1B![&<BSI^
M>@5:!_(*MUQSN>XH_MRCT50Y7HK,5UFA-7<U1O8T&[]_D($..XR%]?^CBA+<
MBJY#(F-./XJ@S@8-WF3I51;;_K%#6GPL<UL7Y:(AMS9P5Y5-*MJ^#+"%/8 K
MZGYL+Z8JXU0.OV"U@2MXUCYW/]E.':6-&.XG;);#6N4!@*KV0.\!UI+@5^8F
M:@XJD-E'ZB5U*V5@V=!P'QUI'S5IB8B^HO[8-\I9/9QR5A^6LWHTY:RFG-47
MJOP)0PBOV&5YJYL-=OL")X/,H-L/6WRF#6<KX3>ZM:%0F+GJ""*QEC09NQD!
M\E\PQLN>X.<&B0"VV:)8<"4-=Y7BR\)Q-6[=&+^+0=.+NXB@9#@U.F9H-3 =
M%%@0@QAB?2K /"/V@7DC @00Z.S[[QYXR,$!^ CO_;/J\O7)O]3[#:+YL.<S
MDY%PM?B!OYKN[(WWQ,"/Y9=!LWG+L/H+<>(,#1&\I$-2^M\IJ0&<=!0PMO]^
MW8I/!SC$WMGDXUA02JCS]SIVGLI0GI 4WHN!O; V=GF.I/T=3])"@J8;XV+(
M&]M(^USO:NJ+)3R\,!L/9! LG_,XWS:WDF6[FU%C3!@NH%ARS2BY),"A?? /
M$AHQ#%9(P8G91H+>WA^"#@X&Z8WK]#V'>=A(V[J185Y>,^=B!&&G#@- XQU=
M5_IDK<JERZ-2E?1<=Y=::I.L+\#OR@XJ-@VT\$CG,[DK./2Q!3,K&[WKZ)=L
M0F;?LU9=X%H;JVW8R]B^*+X_#+")N86,V,XC=MX;\LX8%CI<<XC;Z[&*"#0!
MP[]^JPBA9;>.Q\?-T8M@ABE-&Z@1CFR*VAAMI[Q_E2F-<W$NQH,90K0#B19:
M#L='_SA]8[8+/>]M ZXB[J3L-ZS%T3.F$ZD0UFERMBZ<-9-!;;WDO)1=[?&N
M62S$GG:D<*Q=B8(=UJ*D9^"N,FT@I6B7X<5>B([N2I0"6"-BZ7WJ2^D+ ]+
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M%MABA;J!0#YLRN]$XJ*O>&_/=FO9>#L^0G.%OHQ.SFT_J&BEOZ$V[L1%=+X
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M;[X$!$G"&XLM0EJ*>PJ/3N'13Q\>?9V./]-WZ[JAFJ_8HDP& GY4GNMM="E
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MX6B1UWKW-?NQD]4XU3K'^RQ5$3U8%=]@6^A-7;5="JRU&IO@JCRZX1;?>DT
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M1V@=W:X CR]ZW$6XX6*+08"9^##O^( 9B;S$%L-S0Z88T!0#^BHQYXTN"XS
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M-6$3<;#W20 E$)^23K"#4SQHB@=]^GC0V_A%-WW\GB7QRVU4%5W3Q1^$%.R
M1/CK$H!#3<@"[Y. ):+?;Q-H[Q2_[BR^!UD6B3C3>:F*3?SH1JZP?T!TMR6!
MXR.51@KQ]TC;+Y>ZF9R6R6F9DMB?XY, BVQ?I4!/GX"J4TN]ZE7\VAZU4D75
M1D_+M3KOFP2LHSDU_8I?ZS1!'.PG_F9-P$@L*@0F)Y$E90Z/^!Y$ K.2BNF>
M0*0A?LY#+<":;749?2@4L=1/V9?)D?D<CLQ3N+*H^@1B)P(\K^-3I=1S&%N&
MP,<6)0&$1EVMZFEY!))<%/HRMA0)'-(3?0%_\,A";1$_4Z7?;W75ZM/8<B1
M^I(,@BBO^_AD</'MZ;:?_WMR_S/2FEU3Y$F8%_'=?^[!GH!]$;\6%8-TBT9=
MQC]&EDT=O38X 2YF7IO1(U,)^ #QDTT)F+O3&2J?^&<H6+FJ3(%$[G(=GUTV
M ?T0G_5F0J]F:7!Z)( *4-MM4U],$?,I8OYU-C5J=*X3:(=Q#@/9*&3.B2W)
M"G9[4Z70-66J[+2?A!H<%55>;Z+OETZ]CRT"# 36F,;7'8U>8FPV>J#Z[W5\
MN$5\NU$ET9,AOEO9]O$UM]VBT><CB<1%$@T<8PM0Z542#= T09%B2Q$_:9$
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MOES2=M).TF&D^/)E7:WI<15]%FDG-,S*'J3E%L^[3NOLK*BJMUAPT])]7-1
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MC@[[+K-(@4:0A5'/[5Y4PL?1>/*J%;ID+*A>^^"@VT+W^_3$LPN'V78 2'I
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MF4*])+6.!;#T[W@41J"A2&1A8JW4+HCM(G*ONBYM5%J4Y(TL+I*$.C@,E_-
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M_6,@5U.9=ZT%?IU([;<Z:)TC@WMQDT]/&*FP%&"M2F.P.JL]FI\0!5!T[,(
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M^/G/OWQNZWQ194YG)-4RZ(@-"X93$FGH]X_L"QZ;DD+F"\XNMH7?<5EQ,M1
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M^W! :,R;,*&$F% Q<('()+VP7/LF;A=MI_MW![UPPRMOP/DCP1\:F&<]0AJ
M_4FT6+M%>N1A+13#.\1&;_W5)H\>2=_Y00G:+Z<$[7$)VC]."=J'D:!]Z*'W
M-Y'9%,^#<N]RCG)YD#H3K.8P[@ISBPXC_L51OU#(I*9:X]S;&*XY8!B\28L
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MSW-.6P1)#-2+GD9;Q5,BQ*%;R#2I&&"R-ULMFL[V(6/]^&F7=77=KJ+A?C+
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M$,:/FL*\YO8#Z ,5.^G2E9:V38F.,@4OHZDX1%, MJ8"U"N/U\&&S\2]JK-
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M EZE46-B>QRU;NI)AH=PI03J%G3 99&]^"/@.B+PDA1G3JT&J@A1("#D@*Z
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M6ANR"B752<:_JK9\C)4YQ2-,.;?EW)9S&ZU+=4'IO+$9?AIEEF*F$R%PJ!E
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M3@]'&CL!_=IH>SX&*22VEQ3RLKW;BSC< L8] [M*E2S>V*0F'T37U""QRAJ
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M;@LK452?B39+5//PYYNKVTN;ZK8:F'?SHI;KX ' $7%K",.(&^^C;AH9%-2
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M6Z37Z)O5Y.9"LVF0LAA5WX?M7[MPAIBA. W"MGC[YN]\)28@C=\8 *4979?
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MQ-BY":LZA(Y&<?.4F><CM>QR56%LT+:\01J-XQ$]=^+W9.M[;@8:=\H$4K+
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M'ZPA$6F".LR.0=DXBSQT.PX!V]!0Y9;C U2+PHKHPF03'+#"J!&%#7CN^_+
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M09D9DD].B&!\>K4__BIR)!WUP,:0=2G_YG7<%DRR!.Z% !R Z1&JWG#7!Y4
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M<#J6+Q\GB#LQLGQ[W_0Z^%%E_:@!F;44H/I3T##GGA""#82&%5QSY'0 5!G
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MRF1*M@#WA[ E"=B8(MN$:A+TNF.  >+HAU)E?VM;=_@^"&_U9_';[1W]VU\
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MC_W&_:0T=_0:FN/7_O.R[P<GU\T_;N9-<].UDZ9,<]-=W-Z>?;!=MO=+:=
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M<^TR<>U,H5C*NVN"/)H%SJ(=F(-QNN@EP*'T5V( AU^+NY]?;DX_/_Q>6ZY
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M&[0B<^5,H1+5>&57V" U))-J2*Y*<%:3'QT3FRJ(S5HR. DX^!@N*1%T2XK
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M(*J9?"$%>\5I3<F@7%RNEW)ZO<1G3<F@7'J]K")ZL2L71V3T(A>(7EP2Y\P
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M?AX48XV02<?PIOHN!<2D?+A3?+BHR9A+$YXQ6E,R*/?WS4G<8D2BFBE4EFC
MOV.L%L<U)8-R<;E?\NG]$I\U)8-RZ?VRDDC&KMP<D:&,_/1!O/V7AR-M>-2N
M?7G-(-Z%(#?I]-W-*K@XCQ7:D3E4Z?3=[;-Y.GDMEB;LXEFU5$@2RUZID/R9
MD)13(4F%)!F[B-\,S^GQQ?6/TBA6,K7*$J-NXBR^Z?3=5'*W++FI:+ZRQJK
MZDKR7EU)8;'INX?NE5MZ*/PD=F%[,)-%J!&30;SYQ2* R^YH6X'D5U)^:^57
MU84'\8Y+PFIZ #_>/3U<?WVTK7PZB#<X*&E3Y5(5T.G%?*::2V=_IBHE7BN/
MYP2S3118+6-D_:6LDI1U)I?"213&M0_BK:(+M*M#!U/I3 Z%$S&(=_/1PWRQ
ME"F5BSLAH.D@WE0VUWUSK@+8!>YCL?;:(K6X<\6_?S"(]S7MDB8&G*73=[>N
M!Z:MY2^;@)>R1\H>*7ND[)&R1\H>*7ND[+'UHHOBC'FFF*:\=BVE)]O$ZT9[
MAH4OLHXA>\T)S#G5K@LSDJ C^[I7<.\'C=+=:R;W[N1LE<@AODAS[(A)B2[)
MWC#?MB7]\TGBQ)=\ZO.<;JH&YB7ICU;$Z#Z[KT9NUHL-N/]UK'_O7/^^_ZK,
MG \\A>VF,UPTF&!CFG:9R5K+GVXD+"SOP<(*F\(5E#+9[+*]Z[8M<:G>V9KY
ML2BP/U]9KH [GL2,RS'N-DNM2<\NJ6'7G9.N%I>%;L63&^+"A[LM$XNJV5JJ
M9E.6BJV:=4Q?T?YE*C0R$E(>KTNX(<(A4H]<2S.ZK/N':(5Y<>:>] ?EWHFZ
MSBDP^5=%,=86LQ",QT?"IO-<UA*KJ"W(BAL)(5R??'-_#H]^GWTI>R$$P08S
M@P$QJ 5; .8QD[0Q"004,OE7Q0+BR^NIEMC.*F,D8=-;9ZU>P&;BD5.ABM&:
MDD&YG1*J=0=7\I5,M9)/I2Q&:TH&Y6(2QRDLW@=GQPX@CFM*!N62>T&L."Q$
ME?]KZZ+CQ >1,:/ #.&)Q/[HI'?4.&G;GXMWI0U!7F(6+/))DH:+UADN*D[G
MPHU$B/+WG>OC^\=*-E_S(D0+ D9BJTMI[#W6Z)!<(5,KILYKG-:4#,K%Q*PN
MYE*S.CYK2@;EXL*ZZ02,&*TI&92+"^L64M:-SYJ20;FXL&XQ^:P[+XJPS #=
MUNAWY?+Q\/#LL#>JK1.#DK1*F@$GG.28$N&DD\P.O J()YF,>JE"64<HXN1U
MK+R1,(7QTU!_W71__ZZH4VIA%F*<) 8REC^+F 0Y*J5:IE)*HQQQ6E,R*)<,
M88L!_N6U78>2SR)Q7%,R*+>3PK7VN;^9RDYD0E-AVRUA6]#]+J5CY6.TIF10
M+OGWQ(KA,'@'E'?@#IC62\;SO]<]<[DU^GJ2/?NA_G@8F(^Q[BBSWJC7_AXE
M('"P3\%4X\5EE1L?Z;MCU(SCFI)!N;@8C8L/VMVQ XCCFI)!N:UBI]=MM\0M
M)E'.%"II66F<UI0,RL7E?EFRE=7N'$ <UY0,ROVU]\NJ8QF[<G=$!C/J@6!&
M:&9P:W3Q]/#R_4>IWGVJK@MVDTL"[ ;(LK^G TFF'GEB1G3'><SRCLSEGA>Z
M2/ 1)(;-TTGT<31BRXMGUE(A22Q[I4+R9T*R>+E8*B2)9:]42"*W,6>4:,@_
M63+"N/YYHL5*II1= O@49_&=/D\TE=Q4<M<HN7\<N_G;A#,JJ%.H1E:7C#5;
M#0U^;6G'K=%EK_B]=WLST#Y7-@ UR;\O14=_%J%'Q)S7M<5_#F5=-A22V=]K
MDH%#[PVID,W083(+,Q#=[1]N=(L&VBJ6O^VBK5Q0 B9&=X$ K+<NJW?V4OA\
M<ZV<$J\LBW.6)#L2H:N8*+J*U/],<E33;>MDI6>RZ09>XX<0.7YZ4S58U7PF
M6RYG2KDE*D5V1TQV0VUM5EQ6?3;_B<F^XCF&?A-%8M4E^K>FLI_*?BK[VY']
M=>/%BH5BIEJHI<H@50:I,MA<F.B5VF#]L=U\K0#.P4[K@\5#OJDJ2%5!O.R"
M5:#\BKE,M?27F?\B>/R/(P._P+_8?_X=!-_'OC[O;<&%*P0.ROHH]66KJQD'
MCCGX(&6]'P7!LFO<V^!30O?1)&1_KZY@F:-L#(&_I$O3@2<XIM0P#9KTD1VB
M2B>:(1L*CBSW(I)V:/>OV3O;V(IW]&_;.YSVIQ4<T+H6&;6\_W=P )0FNOI!
MNI:[H%";Y+=+# 6^5RE]E"@2&1XA'1S YR7XOW]5[6FV?O93=T&N*J/J&..K
M,EU8B$*!-2_ J1'/#,C*R4%P>V)C'Z7;X8!@=DMN:\I'Z1*T,MO\I8G;K :_
M](_X%OX%B?;O/[#_*%)81'X\:!/0TO"T 27EDMOWCCTH[6-O#"X-E\S.Y<_9
M;!7<NE[5OC8ABUSVK ?/3HNN17CKAOQ$7O;W+K0.D9J*AAQI@[JT!N\7(<46
M5DQU^OX>*'6G1Y94[/'9A9<-W=\3Z5")0M=R'ZG&D&JKNY&V*#[,(+QT^_!E
M96'H @%#<P#K<BPL5@D;MU=65S:TD8P&IG_X\$/=4*\M8L.9TQ^O.AXW^,QP
MI-F*;MJN16YA'8<ZV,E43XH\9S5[',ASKOI5K='H^:K\W#M\.G0+;^)\H"AC
M^WLYX,C:1_9@CT+Y"FSCBYYM/#WER(/RYM.A:VL&L6WI"([-TFB[%$DV5.E0
MMC4;6V,&:<491-J(KHW_%;'NN=9HFVG>$8&#%FFJK8[P6+BF=8:KWX(@?P(W
M,..*E=ZBSL]G/[+/T!_@ C M>K?QOS68/\/_^$X"H9(E1=<,A!;!"O&V:&OF
MH">#&Z\0ET*.).X%2<3HP@=423/PF?M[*GDBNCF@4W= -E6MTR$6_*#1&Q0^
M8H'JQ6?84GLHR8.!3CVI@444S4;1[A-54X"=T*U"T]F"EQG$>C)=6[*'-J@_
M;U>-RZ:W:E6SB6S#QI\UI[>_UP/'77*-/G'@RT1]+S$*@.*0]>$(/M8EAMF'
M.P,TKBQUX++PM^S@=4W=.@U12W!<N'\XT$=BP3D\]S2E)\D6D5S;VSA[,%=(
MFF-[3P-+@CVNPZGN@+WM"/(8Q+5,E<!B@"Z.]D2H9N._]0@):Q+;6\AJB@UK
MKLSSW]R2;Y&) R*1JWRT06W*K+T18NJD^F7]^_'#O[8[P U6BKA!^'?^H%*0
MWK9UV5+ HD"-2&6I39"_^6FB")B,!:2Z/NH16(SEO88?<@8L-.M1 X/ $'\"
MN6)_H_PQ@.L3)4K7AY*)(C5-4 379(!+%=W%F)AD(>?Z?[!=9&9;NB$.>+]#
M0P51@!7([',V+!O^AS*D;G890_=-PP2.1>'1;.I(2XI,90$DNN^RB]@6@O%P
M )+P"']$)L^ >#N]H7[0&)P>M#4*+ +9A_W I_.>8'\];ESGA6C_[2R_H3L<
MK:G]O3%S2DKDC9CX*QV4D UJ2 DZGQW/^;0])T#JP:4&&H88>($.0&+##>11
M_BQ7AW>CVK!(U]6Y<,(YXQ^;1'$MS='X)XY?E)YL=-'M[?<U&^_C_3TAE,WC
MAG?;XH?Q^Z"DP(E2V#/AA2>FU8<]''RAGXA8'>A/PNY!65% FSI, 8!ZT@8Z
MNY;A)D3%!G]'']:W+.X,#7^D+A#=0)UZ?;*G->[>-]]+I_7Z=:HY-JDY+K3?
MKJ9JSC"1HI9X75'7=:JV6;0J;+=XAH*D6F[7LV!L:KWR^]DS>X.6.[/ZA93S
MQ\(M;QBF Q(-]H:%:7WX*Q@R:.[BG0&&#UC>^*7@HT@'+%\'[7)=QZ^"P0'^
MB=UQ=?!#P##I!'Z3\1\X=>GT.6B6X,/ ?[#,)]2.8%W;LLZR,6%7!?4HKA^5
M''R*V]H$']G'5JSP"@N>9[A@74NW)GH$8*<\$Z:^<,/B*ZJ$5! ?9EZ#Z5H2
MV'46TZOP@ "]R,N *+ 7I&&;^\@TLHB!*@V>P89\P+>ITP9F5I<Y 8IL]Z2.
M;CZ+EW@O\-P(#-?;A&!N4.JXCFNQX^)'!/H6O"@'?!5B4!HCP3)TL?Y"^IC<
M!"IB[0\:81V-IAK_=JVY]B5_!5^Q2]A,XC;1-3@;FS$^E4?70G]9>C;1!P#.
M9_ Y$ B;PNH"@M3I:.CNTZN^3X@3J0/&GV-A#Q^+VP]M,C0-%7BRA]SWXDBY
MO 3FO=,#%=%Q^$V- N&MST;!F6>64/5"^QXS@0#F0@FG 0&4YJ!^ (ZE&L6T
M'7V88?J#^LE:'Y>-/YJN@SQ*OS_NI5,_W.#ZZ#WC!GRE#*_OL][*DCM LE&W
M/:C.>N#VL,ZUJ' (G'.?FA:TI:T%+P4Y 4.$/,FZRZ5?!389,N*W?X%LTR %
M-9F"KU8<%Q8H]]&^D::H9A1[<']0<+E.>Y*M(5!FP*I-Z**!&I+ATJ(F>$P'
M'FQ:=L"7:[L.55 ZT,KAOB4>&$&H5"9(0M5E"H0^AZF+,4IFZ%?AI+H6/ZJ(
M90-=N**7QO4\_:;<M[U;0\<_TO=Y+ )?!A6$X2GY2=9TJFU"&A./A!J';4T'
MBP(W)--N5?2(N!HTNOM[ QV%4="*ODH<IFD$^6?J?E,UM^8E7V%D E4+/ \O
M'HI20DM!EP.\>@W\T,/ 1AWXCJH/Z2TP@4HZB!H$48-;$$T53!E(I7>42_$P
MF=8P3"KH%JW4HBI*]M#'@N^ "5"^4-?Z;(>O=VUZ/]( (?(-LT:\CWC&B'B9
MV6901N0PWWC0T2*0;7@C?2RQ^F %G(6D!\- **;X"7K_LR<Q3H]:+V8XD(%1
M_;31,6<K \&B"X8EX1/ILC/XD[@2P"A0&&E5H/(0S1V*J9)4\QD.%>]Y^)7,
M+<:@W38AS@BQ>J*>X2X(RC^A1.&G->0-F[ A#>YC\+SKGF=[#=<DW-#VM&Q@
M+5CUN- #6J/>N?'MS/WY^^'R3U)\:TGHY:/R>:76*-O.UNZ[]U_:-[_>?&JZ
M_3[>=," @2U+_IXEL>EUY?(2G)V^P[D1Q\)2"7-3L1K@IO '6Z/R;^WV2T>_
MO3C+_PG;;":B,,9"Y</62#U3+^^_7OW0J]TWG^XP. ;\X^W/(_R&_/>/$J^K
M!XLGC49,I$]8M,^W-Z-<!+C^, )HJ?3JQJ2=Y,7OA(]BP\*%JT1]'/F1!.UT
MN+*"9CZ[_SL=:I?C.F 9ID4-=VJ*4Z,6OD <]EU=8V8FC7XZOJO#3=]HSX8;
MMU&/YH$!^AEJWF,Z4C.8=\6^0*.=!)NFANU>%IJU MZ&/6.C 1,J$$7%R,#4
MZQS=*QN\*_ =,*SRA.$?ZO=;1"':$[-WV*L%O@+^8CX12YCBZ+N1#K$PBNO(
M+YR0&8D-)IV< ))A-#;!EV#ACBXQ4*O3C7LI-OI%>]P!&]LOVEO<*T8?"%[:
MT^"U%K7F_?@)>R.X41JFP%AB3/A,PI3S_6T3_HTLXIEN?FA:T2S%[6/ANT*X
M7P2$=75VS,R11% ["^Q0& H2']@3S^&7JW8YL[3!B61/E"V+YKF1Q&2,$??W
M0IS(.0Q.UD(W$GU>/+PP6S%>MUA\"C:A:CK-ILN,2C1H1 G '2[&;MPS%9OQ
M28>I.\:GXES0SV7)>PD/Q6*6+CT9%;C"1M.4OB;2N15'20-J^ G0.E2(J?&.
MZQ8/]1 "Z!6VB?-,")>8,#\X$\O/",<N<#:!0)FPB9E"(.HNF+%@4) 7=/Y)
M\.;/%\JM44[]W!N5'HN_VBN$?JTCWNYOB5KE8C\3^YN%[RY/Q7?[-,F#J6S7
M.S]^&XWA\'%.TXZ$([]KRR&_0T1R?SP<E[-/V>/+DD^D[6'"9S-%D.FK8!66
M[L$ZN+GL7W9CS?03TCRYRW5H(WS1-.IE6Z.N]J.O_NAVJI^+4=2++5I\<1:I
MM4;/)\,OY+YK/GZ78[+)UP/,%]\X7 B?[WMJ^?[^ZO2T$Y.-S\6DY[*OVBPH
M@J/2C^%#H]NQ!Y4_VFQ048V]?B-1I! ,G,9!AE-B1\7@<(!97VN-\IV.\OVG
M=:^?1(I O'W_2FMT>'1TG?_RTK[3P?>_]K B- 00VGD:!HC+A;<P@(GELD@0
M$<2P/0RN&X5I1F\ _<7GG@DNR8'YC"%YVVW;FJJ![X?+XM^NP\8LV*2\OW<-
M'NP%SY*%0='^IP1L"-&/ MZ,7K(%GCO=@>\AZO(S6Z;XKO?.4V+U\8NG_?;G
M:0_:WYM\$O\>\V'YLQJR(:NR=.&H[Y=8$\VJ6.83NOKX\Y7AH$N<X8][+]7!
M,=+0,CW@3T2,,NA#F>.X< 5MUOTNB# CF&4TY!UQI3:@RV6[5S=4_!^LD@?/
M'SE^ME+/!Y7Z(M^'JR\_L*]*U>?N;RUYVAVLT ?CYP_CO%!_^5Q[\PDWRR
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M]!O5FUZ_9E&>RK(0!L=Y8Z]//L>*MKGI8)%J +/]%ML5O-#!H_#(=_XX4,U
M8)X.UP+H8!-12'@#.F!1(1R1:V5OJJ=XE_]@.K]*HHXQC5[Z#7H$2)L_8R!;
M# 08B-CV?>9D_7SV]^K1X&R6V0B"JV4G&*IA"41,.'NX:QF^9!%RH&,):_"S
M/8U86. Z9$\%&E"$JDC,T- PV-@N[TG'WQAX @\K^\_IRR]:WWN RV^*-J9
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M[.W/L"B<*L$'"NSO=5QL%BEYA4T.;?0X9=*13F0VAAU?G9'JE_7OQP__VNX
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MP86M64QXZ0O%(U7-EKL6$>1UT.N:\)ZIR\1 EK2@@@);V"9MMVU38P#L_\&
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M]QSBK$Y]SXEN3%'?]51]+\;#/YZ-L_+WD^_/AA(#'MZL^MX,#R^OOFEG=\_
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M!)[UY +F@5L?-D87G9N3Y]-'Z3BOQ 3^. )PZXOS_OT%:1XU^Z68+'(=X-;
M*=<W0N%JT)=.K4!.B26X=>E=BRTV1OU^[N7P],]=W8?0O]G%+L'_X7L?J*9<
M!>WH'AT\?K>#23T^+:(H:(: *D7]2_A['U&D[-]=Z[WL=TW,>&NCKV;5;&-$
MFC])YO3!.)11C%@][.E*7_.=\SP9W $WUP/ ?3TBIB@KQK=WB/5763*[^-7,
M/S\X^[X'2:B(?0/.P_GI"[V$_F/JS@!@9B Q*(X49??:%^>N,B7GBWY1JY"V
M.>F8+AV"H+F5GHRCKMPK7+HKD&2CKXA#O#=4&/ZNU262I4Q8#SZ5UJ464_(F
MX5*2_X^X*/SN_WW)>J>6*Q<; >[_D78\*EAG0VV4[WX)6A+36KX$#K3RZ),^
M]M'CY9^[G\KS8?^B%>GHA49 C'1TI1R2T]N.RI/G94>'_]-AM(\2BO/FR$3*
MV$:M911OYWE^[FZ&Z@3R71LX#[@ZQCQ!WHF]C[EM^>=JM7RP4A^]+W%LIV=/
M;LT3\3/;/(N*]RRJR#</15NR=>_=.B'9NO=N'3]7\KAWT5@U];B/$]6HQJBN
M%]NO#^I=7_PR7UZ!.@/+[.B:I4H'MG'W/]5JK79\'"#*;#THG_\GU'JEI565
MB7D(H4YCWKTT/BX?ZKC_6FI(_I]Q"J1%4:$2X-RH]S21S8ONCQL4RV7#9=VX
M=':J/I2?"8B[QG-:GCX2NHP;74YE7H1 E<69.7 )44:\WETBS:ETT# $9G9F
M]O!&:=/39OY-_47!23.^#)9*OC%ZNGKYU7KL/+:./0M[+/XQ'?UPQ][2".8'
M4QIJO;ZB#0G9W\ME^*\OW[A#HI*V;'(WBJBN+=,AR=N8F;?1I0UK)#@3E:#:
MK9JZW+182V9Q "+#X/IP5'8NQYT-&6\?IIUG<(86"':DN24#HEKHZ)<(Z])
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M6BS R".I]AP5BCW%4M7K.07K"1AYC!TCA70Q\9PF$?OM,'=C#D9>Q0)/14G
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MVHZ 2/VS7G92QXU1>30\>S3^'/T^S 9-JJ++HI+B3HDR(!@%ANF(JG$P.:<
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M!A<9*YZ+T8Z\,WXX57=4OSFZ+MP\29UF]],RV[N+GN8P&ZB;V16B [&@K/=
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M&^KE"SVXLKJ_5P&=01=!4TK9^D97'*"'P^</X12Y3< F&(BR@@%PU$.T=MN
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MIX2#0*?^X [5O^TO@JYOR)(LZC(Q;.H$+I-D PB[:<$#^WM <QAY,J@/P+"
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MAS'D)K$(OFVS6LQ/SQJ,U]YL3R1,NP?OH8F0=[7JMUV0M+&>,LW1V-]S-,P
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M0^Z%#&V,#-J7FD+5( *_%*3L,3J$]W68'@/& +RN@XT%8J$]A"3%'%NA]H;
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M#E:\QB_JMP"K3ILVIIJZA@MIK&L5XQ=N??S 3<BK( ;%D2$5!?95Q6'J;/@
M[,883>^M3.0A*O"5NMB!*BGMCV.ZIGHM!=5*S "S"P3F[(.B4'4O#+2ZG?H"
M'EJPJMGEV&&0>J6N3Y'@0I%N6UX7'RPR&%2-5;6U%'8U%%2.PY=#Z6O&LWJ@
M!;(IYU._*9Q[H*JQQ@4@2"@^;(.:OCT&\+B/CXUM6:F L%!374JP0JAJ=+M1
MHW 2[@[37Y&JBE/M[D/7Q98*JBH?+ODCR"F06#N_QB]?^M8R2%<?-[GI: Z<
MY"'O*'.&>*\G8:,-(^#.8)00+#.4WB F-(!;PD.FGGY-GA.\Z\T//5^\!0@R
M^R+JS]*=1<Q?30_BLB!JI=IN':[M]L#:;FVN[?8\:KNE=MOZ]YR))&07!]I$
M9(%F- O96M!B0?&C1.R".DZ$(^Q&\9#@Q8(7/RZ&03!,@QC+)K# 0@K02,QV
M#FUEM8X(-==DG\UV@M9%OM&B]%(Q 8(B56A.]_6>*8R*?2&SWJL-H)J8CW^\
MTY:>ZKHPH9)1.J@2VW!4RR05HX"O7?O66(%A^=3H0'?EGIK..HQC8'L?^\;&
M9O9ZV&[7ID;V:GWS):K3:##SOC>!(_.J:33%O$IWZ([?B!&, 4Z.!K.)>V";
M!9?F2R_/L71=/-6+7+?/HC^G8B<Q[NC+ )JRP'4'<^L6N" .9\U3Z[U&<_(=
M4Q+$];=GHT-@BE&)NW Y/_;)E,%(4*AH0537I< ,EN89M::J@B=KA!MXXU)N
MJ8YA5A2./ J447MD7,P4&X(J VK\I1:"=O:T1"+L9EW5/,QBZQ*8VZL(OY%N
M2#O?(IY8(T;T0&)/8TL+JV38)_:&%\R@^[74Q25VX\"FR(ZCZ;@<IFH%[#(5
M:/ E?06HK<*9R8:D6#016S61LVFE*9[LHZ("E.BRPCNF92OQZ4#W*\*6I,24
MU/T@;BL+CBQ^?1J())ZT?6KOL71#C".L08^]2.,@';S8"CQ7&3W)IU1896+9
MY+ZJ4IL(&VP0\H2B%\.38XD.LJ2JGM7*0#7 TIXW.=@J_JYYT01HD-;4(V\:
MJBH5PI2-MD*-QD14<(NG0CD>1CT,)ZG@X-G13U/&BT.--AD5'AZI$(OA ST5
M2O*,&:!TM;(!5+=#4FQQ0$Z7=K=T; U#\_/1V$3+;(JV3=N;3_OSF/,451/^
M.K('V/$A/NV@PO.JBJ\G;+1) 2]HHMHW]B "V2/^AG^#W-6MDWIH8IE*H5HU
MUY0>U;:7CI[IK\259[%QLHN*$X5A+_GXR)[$Q>H7O"6V(@F& 'NA8PR,+.L
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MZV]4WTVL1QBY^I<LC(^D0]!1F= 8#BS4;@78]@!+WP?OQ+%?%Y\M,?&" #"
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M@3&^U[ $PG*UHM"L.W@*M2YQHIO:QVXS=61;W*!S S?.$Q0V'1]VU]E_ 2V
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M./+\B>=;H5WB!>?HD=;VFZW:;B/7HML<==@HC??JS><==2BR 5SR (3X9+M
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MA[F+B4GD3[R [4NP+R=1 ?SQ_ -6D\)<M2O("4/NO%D(G@AR][Y&GE, D5V
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M/EZW_UDU&BNKNNX435/LM9O-%@S8Q8W=UEO9:76;H"<ZZ]<3"6,,*:Y"]QA
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MX$W"5);#^I)ZE<$W%:GEVI%T?ZWX._(RZ@7VP+9\6Y9U/[::N>S'UF)'\ '
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MMYK'4-YJL>+X\9RWX@>%LM8VG;7#;)E5N_:3-V"#E(4S^,U6GOTAY-F88Z:
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MQWP1AG-Y$K0(#U,+ 1TC=WLP&2YK4?._9Q$*61NK.;PA:XP;2!XOC$F;ST0
M%]&)HW>3S@$^S/=0J<$37W L0>%W/*(?;[$:X*HDA>=0YDCCQ.TI6X_8]?#R
MQL:KM(!--)/ O<=?\ZLSC&HL^%N&'+8F%2!I^CROZN<(+/KS%EBT!18]-&#1
M'Z38ZU?4>IT^?WER>(5^6R>G5\<7QY?;*N&[BK? G@"&RJQKUX'D-F0E0GK8
MYU U^LA%HSX2&=?%6O4 E]@&/_2N)D),N<K?X;2!BQE^20.3(;S>9&P-SX\K
M>*O9K./*8;+>F4[!E_+ZC_ _YOBWUNR0V=NP.>/_\NXA3[P:[M45<3Z#+(["
M]488*,=1BL-.](3C'^X7CEI,>, C/*$(&#16SLQ+DC;1F'QG"08HH ]*#OL%
MSG\;DES1:C*I^X U/E0MD__.\1TN=A,:=2Z(]1TJBF45];X*\YOW4M9C6&L:
M#K^[R9<TNK1TTJ-!OFAX:3+ =G>L;]-$3$GIYY0(+, //_Y.8DFDAI_,YU(
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M3]%?B_6_W5 T\A;;9G(8G2=EFX8(LA>.<R'0I"/4@7"FJ,KK/7"RA+VF[\Z
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MRB/CT_$L4R&!JUW:]HOZ ]W_2$6IJ*U>/:F53@Z2TM(].R($3M_0CG'AH$^
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M#-HNWKO4S(<;P?NIM0_ROG';E4LZ&8^GURN$]OMT3@KKCU>L6/>T EFR<N[
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M9J&IJZ@CNN]Z*LD0D,>3GZJ/K^7GF5]J"7RRLN 8$&<29,TE_L)!_CDZMH)
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MQXZX3A-I4*Y:/?:'N:"$^3OA:?A"[4CH*SSG";AKM:Y9$O'<NKG_,%K.S_4
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MJTF]-<P(&-' %X$OACX(OQJ&&>O4)KEV90<)Y#4J71#T$$'9+,GOZ$JL]$I
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M^X3?ZC#JMX77.2)SKD)96?+&K<VGYR(OX9R,9%7<DE?BN#HI<$N"K%,K+VG
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ML#DWU^@_K?\NQ.NP0>K2;J8[>#-P%8;-CQ_$<7XO#-;?MABL+09KB\'Z?1F
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M3/P17:VB8EP!G8%+$%Z62 (].7+3E+,K3YX[.CSK)V<<TCH4>QV,GMQ!>AN
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MUVS)_Z!I+P:WGIZC\H-5>O[Z"5!+ P04    " #2@WM7)H?LDM@"  #"#0
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MR1+X(/8PE/Z0F8Q>)ANP!Z$%<YN0!+$TD> !W"S"SW0("<U(^)9#VG<$WE0
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M8OFMOCG\,WRC>5K&E_X P]XJ?W^AHM]7F/*FFO03%G;-V)^^^!]02P,$%
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M7B[!E)'_X=Q0R6LL)5$A::<]M4QLY+GP?;(O59AQVVBTN#-GY;\I@>?\H*%
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M:V>WJ9J <5?454XM76]LHSZ$ZDIGBQ\J<PY[><O4*)E,JD.AKHE(X\@?UER
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M!Q0">$N"(5 P& H&0L$<4##@K18(@0+!4" 0"N2  @%OK1P0* <8R@&$<G!
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M=K<_9#]7W\XI\ES<SG^58;I;4-.TXQ(/S _3<80'3E$N&Y$T<87?)NH?R=/
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M6YK&/;9J%;,I!Y?K5I*#%SZ@.[+E9VE?'>!65F<?T=;2OE>[IN,#:UL&:9T
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M]!T18 -!,(0 9$L0QD, %BU<4 ((B3:0P#+P/2TRSD, >T+@!\) ?58X@K'
M% \$@VT$:EIU_;R@=!XX ]8@:[A@ T<$F^ @^C9N3EXX_O0@:D^ 0!FW)@4R
MGR> =RQ8^CB8IRQ$CA:9FM!_#)&,$I'87YR<CXIN!)$J2IQ@WH1$!_D]1KJ_
MS4<X=BP>&QR>Y&5_]!]:C,MA]@]ACH3ASKSAKA&BZ4F^G4@ :U,O;]JPLU:?
M@+;PLW ?$RVO4\T(&XF(@(B(F)\1<="(""?3,&>7L(?/<!;S6)B+\N'L9!4J
MM)F6M)[L9$/?R+Q@273Z45<H_3$IX3A37-C2Q#/" >Q8[[5#A.=&Y'XCVG'C
MRNARRNP>RG4@BW"XVCU(2[@D6Q&DQ7P?<C@,BV$WB_:]C>G]&3U#&[M4!F>0
M$-'V.2*J+#:B+2*>,&Z7-RZ&-M*$-M).(M*Y,,!A'J%1ZWTHK*WE-;'',-$M
M,HDL=M0U)<.'N7CGFU!,)P [((*U%58S+:+IP4*P2:8'60I)TTXA)&:"]WO)
M7<+=8#2FE6-7>NP:;T04<MP^82(57V*"9]C)$??96)RC"P+A 1:!.G.EV3>+
MP*CI?")]\7@&J ;M$2Q;ITK2[0,I;K\/L,VE-MT?.S]A33K&_]9^:2F&4"WV
MID3VJY=(F)J]G%5TIN1W'3DUT&UR^%#"5;#8 '+*2W#T+*TXZ;C_^.>(3<N(
M2,\(:J*T'<LXV\(XVO)$[SUG7#%:_P):H9,T_W(2?C[\S]*V_(]Z*S\L\"@C
MB .3=UT4!V_3&6@4.9/Y+D*LECB%[R65@]R42/852'&!@!(%;WAP6GG":)/P
M==.70E.7U,?T:U?AS/:4)CJYF;&,C,?T0=S,"YS,)VKAHI77QHQQ7*5G:HDK
M^.\!9E+VVA'D*ZG.1-ESVFETD6D^J@[=B-PZ$B2LJH3:>VR&.-S)4#;N#2^L
M;23_.D__-5DL,CIOD"56W*/J[J+1GKK>?#( D=M*"-$4!LLF:D3E*Z(I=[-Y
MGIQ&4HKJW9T:4[.UQJT0;XL*]<]O:=)?A9K%L;4S";VE::74$Z34T^8-3*2,
M@_YPGZHIBI0JFW ;6XRHGJD:O_\$X#23 O-D<^H4QEEF!P9GJSH!&"C"!F$2
M69$ TRN%)Z4^[4>%0O)8U]JJ\#36\2F)27<ZX+O\)GPM<VYED4^&>FY\YI[*
MVBE&3!2FITTZ[&X*&D5\F!U\'&X:9M8&I&GYCAG2G&%:UC36ZK?YPNJZ,%?Y
MID#5SN&2<!JE#Q/:47>F'\U+S35B!<N\N*&K9=Q1A:#"-"V8M+"VUXNSB!PE
MT<&J7)Y8 @51#Y."YWA8BP,OX'NJQE9C<?WK:_-0J%:J]([&<,!<#Z%#A_A/
M,6^:NB^_H;"&*FI+*1%1Z8"U9$U+290ZWV.D*MR$=9^UBQ:^\0*\,0]!61F]
M$?(V0@*B=@>^".FX5]S?:B>4\H#!Q((?7M[(WO!>Y4<5.<CU15N%QF+N6B-<
MQM01E8 ,C333_&L\(^2PVD9Y;=,6C;!/7\NM^<S"^!ITRB+,\^Q63?OYJ[ $
MI%*;*W.MJ[2D2[YYJ\^9&6VG%/<VJ0#^ZF8DJ6@U"T5TJ*[Q"V]T>&VO-E#2
MU?A+U*0$FKJ5\W!!?=*^$_*,+M>P<=KT@9413JM&.<'\>+JIQ;K+9EE&H07)
M0&O$3LL[5^,(-]5</C!U<P:.M>'(@LXRO-+[IV:5H>9A+Z5&?*5/'=;\1EDW
MQ<I8("M*!65+-[,'?A$3]8:YIFB&R3+FSM9=Y$:?C^6.3G$9.A$0OCA^>BQ9
MHM0#_!2EDY0,-;&'>9& (=% ZA@CGW:YIK;06Y'Y$OLD!I&Y%KEVSU0JZD(.
M^0C?S(Z#XU9OES;Y8"MTS9CV"+D?A)V=#]+#95F[TK%@-4?,Z/:^2HE^?H<>
MWLYW:7)-/EWHHUEE FT5E1U5T3PUF9SI7OE#)!V+B#*]$5T=G=T=[U)7H6?V
MZV?"T#^=_>^Z""8<'Y82)MZEMDPZSGD*>R#'33]US9)TN\"U_1EQ<OO9^_+4
M"R#M@Q7L*X]"GN*+R$2-<+0JC]?J_6.3^)TWDB\SSL$T;9&(C_V)\\RRXMJB
M0G%9W<7%F%M&):S%C<_-Z@Y/0SW,3<K=ZK/@0'!8'DW6P)7;@+KF (NM"Y>>
M(>NZ&KW@ %77@%+Q(/_YH&25"Q?:$//Z('.6ACS: *WB "5D<#]E0$0S5TAQ
MD"7&;3]TD"UKV-A\2)EQ6&)]2.-\" @9D(,,LZ\/ZPH.F<;D69,..0F.&-I:
M,O8%4K>,1A7(A[P'(.&! (X(#9QCGD%>(3$$$=!G$LKTL0^6(>&D 'A"Y/AU
M!#RM\2#1<?&Q,1O3\0Q?0"HC,AS*1"#%1#8C<@G:A"3O1#YDPB!A(O4<H2IF
MPNKG1*GB>+O,.+YI1%H;5D9I^)FW_QD]UH >I)@ ,F0+ 1- :M(@94B02;3H
M60CD/".G'&DJBP?R0V]J0=![OFMJSG9J-6:J9#1G2Q"K?GFJMPMR5#'=A3A]
M@#:]+SC5%S-]#)G:J<IY\)U^9)R>>(;L0&;NJF:FNZ81KHFL@V=](\ISOWDA
M3Q7"&4<<H_V W9E]3P9 C_T!+_8#S>_U>XYXQH]8&0BI73)>]VSL_2RZ_AQM
M[-P%3W=VHL]9J1X4NHR H03B)@/ $2+S=<\+Q<ZG',V+O?Y2-L_%!!*U6T#@
M75"HGA?<"$3P#/Q6O2#%!-<+LZC%M*A-%J@J1$ALB0#_$V3T;U$RULN :<G8
M;LD*?<S&;\D:'>00NQ2%-B;(M.1FM^0QM>2B-.9(!M"\"G!'!WD_+/M-+<>>
M!WI>Q+V^A?VGYL.K?\9N(-!2CPL*K?#Z_<R%+--*3B3&>O$*K41VK>16<Q>B
M3T _KZ8HK0KZ^69-K?)>K)96K^K/%C)<K1+:K37_"ZCI7FV=6FN>FN>I7FOP
MF^_)7F@76NO.GN^-79\D6Y<2 D%'%[B1 8RB8UC(&S-,@1+9(+%_RRO0J0WI
MZD T+2_,]$#T,9"UZ:+?%.A=^C)CPO)I[%(04]!1]K(I>J"1T+(ITY;SQI93
M['+< -G';,C 451*80T690+[(9_PZ#9GJQ87MV'ZO$MTLQ.:@2F?)K_=8%3"
M,"SIM#J^O_CWX2C,RVW*')</.3L$-3N$S-$,E]MTF[ML!OST/=LXF[N<Y+LY
M;GO$-7L"H[M"Y/MX&/LX!KMDEWSFA+OFLMKL1OO5GCO"<3O"_KLBPOL:]GN"
M1]N*S#L"/7NX_GO?F/>IE _,, Z _GL?<O8)R/?,,0YM#';8I@\=_(VL+G<M
M,78^3!]P;1[08NQP,N^Y,.\&D!^Q7AZQ^!^Y0NV/N9F/PS</]%ZTHGMVV!T1
MNF/PE'JXD;P2%_BV,:_SC"##^GJYJN>#ZF@#>?[#&N?](J,!'(*#E.?#I=.G
M/,L#SK8#+7%#)?XC1<RGG3G#5(JG#7'#9NMG'[)<G4;/:N*&R2 #(HIGQ=-G
M[N?]U=,CLQ@7%7&G!<RC8P;G[C&GD\H72\*G;H,!WU(O\E_.%_U/-R]?;UH>
MQ>>+/C>>*(WA;\_]3,^G[=,G=_5.)UH.C).P./6NDHJCNK8%ZB5#N>0C"H)G
MO,^7#\)7XEEG&\PC)P:C/Z?[>12'L0U/[WJNT;>&QG/.6+-&EH6OFPW.U$>O
MN='.>S?/12#G'PQ'C*""Q@;K-ZL&'I7VI_/VYW:,(ZO"UY\^7 SYWPB)#"M6
M7=U@#'L&7U/XMNCX7EF2CO"@#=%#?F\:F+<AG(G'#+0M7C"QN++&$IH?IXK+
MNUO)OD^N^EW5<[U.?MFXR8U!<0Y4O+1%NYZ(&Q'X<BWK,#C=,^C^8="I:XCE
MPQU[UQ4GX^W4]/U*S<5'Z) JYH.;X;6#B*53_.5'6^">\@CM^;UN[^G7K1$O
MS+]NBG<%T-]GPA>?>^_O#6YC?CWJ/M_MUESZJ0XA;=TC?WEB@)XQ0%3,2DZ_
M.MQFLIQ?&CS9NR  ?GT,'8.5Z_CQ]Q++RK#?(F(4)Z;1M3".0*_?42+2(=CT
M%]3#58*HWQHRB"7RLF_X<ACP<IS[<MK[<K[U H?IZMGJZ5WHF9CT[ZSLWZ+7
M/TC.P^46] 4*A6)BH<!C4&O-;HL%(^,RFY5]-9*(>$\C+JGUPV0X@I':>KWL
MJB\PDN(SU3:ML]E@^/O:,<#LW(%".IOY=)'V_*%2%B_<.5H"3BD>$3H<""VO
MCC:Z #D,GRP*1#OX>HOZNUHO%'Z+TTSQ+M)9*%HHE!/)2/;\<:[=9+588[ZV
MQ-0?*A=.M=BF2C]>CGIF+[2]:+K41:%MF<6?2JE=HGO KKA]=6$Z]IWFBS+?
M=_:#I)C\"2'00H7%C%RU-XU\2M%B%Q,&";Y0QZG&*#:T5NM:>^V/W3J3",;&
M1B?+KU2AT1O2GB:'ZPU6,6[[JMMRS:*9:$2F:ERKG_V^O_E%?/\V6_:JB 3%
M*KRW!]Z>+-9:;&W^>[HS+=1-$Q&VWNSV0.C]Y/OW6'T.OE#A8T=6YQD7/&(0
M"T<S/FFY&-)D$&O!)#WG9/YE6V=M+5SE[WB&[K%5^M[*_21CP;.LTZJNG]@A
M9T/K)LE.TH"1AFOI<HWCRA%BN_TI5KQA$@69]"B5!('"O\[3S)M-_/;Y6PT?
M[<H.B5<=!"HD*Q3D:-^;534@#^*Z*+)/ZE54M,?@Q%/_:(%$%59ET:/T88WK
MO.<_4KZM&69_NOT]@Q O.2XNC@F59QWBB(PZ5<1;T1N;0NM$J_]1(JKZ?C@^
M:'5>2B*EX%KUJ]_?,IE-]YMK0)K_1_MRE8 GII)^<FO&<ORO3<P=3\\F'"QS
M1J8N]>\[=RLXKZY4;GC?PZB[:P/'<6VK<-RF%BMN7M88YF(0GR8T.7^<UVH[
M#NIS4_Z&EXIOE_@AU=K=U!%=PZ$J=8.JM:R55\-EO[&8JC/<<8=-R2V!Y[D-
M]CP=-PI1EVI;\/2I*(\FJM [SC]?7YN9C*29PR[@XU'Z(]8$L+N?^?X/[9':
M9Y)33A5Q@X&O.VV2.EEH?"BT73]RRRS"O)N]P6N6'J\K""$H^A-O!=[Y1GS?
M?-$<_BIO/C0YJH39TQX#(J$[[9E/U  LLW%;UDVC4G[']63;9.%OE-_\.#1[
MEISALYW?@J/56=_))=$7V/YDSV9YN)O*93?PCN56P9E,X!'8R)3TX.2RB/!D
M-ZRO)FC;1E-#6I 2\T=P03W@=DIF3[FYOB1E3HGGF*5U"?)5>POC6;9M0=W1
M,0]]V<]C$Z?BWWT5B\J_/VWA%G[NDYJ]'1Z'F;EUYT%8N5B0_N6.YP&Q28/L
M^9\%I?[NO_QX'$RJ"$Z?76[G/_#2B5%B;CE?U2*]_%V*'L6Z/X49Z?WSE!:^
M]0!%L?=Y?D=Z;^+1MTV#&;#*0?%LPB,*=7,(&'N7]^=&$[QU4AL(/1O0O^IJ
M;?XWCNF-8$L!QT,HLH92%VP\F'6#S"MXX#032O21$D%71A@T_LMS&X?B,>9S
MF[)8K7/3[QV$R-%!C!<F7TU3H[N7>Q[X/ED_U2(3^RL:YBFK2PO=?1."[@<I
MUK!O,:;4ID2+P17T)=]B>8S[\6IFF[D[V&B=],:-UM/Y^2?ZXIS73<E.D$<%
M3MGB_4@5R>6PQX11;^)"T?8I-\;&9+!5$EU#]F>IZ8*EI)V^ITE2?_IX(J>@
M,F>0"7]@)#\^_J7#";&$VIQ!]5%:HV<NL;2HF,&B?9RHC#VU->2 ]B-808L*
MD%YY2\,6:#5NC/$)S*@%Y'@<4]07GX^?SH(".=,B9:U0L=-78SYQ=S]"[#ZI
M9 5##GE[(T==Z-D3]Q5+^0X\Q_0JYN-/7/<%E]OEY)<:$SO72S^9CW\QQ)C*
M'<(U)[5JE [YM$#CU(7!FH(-TG/?R<?80)&B/!T)WW0J("2+DA:8^!%M0%E(
M*@2249!7B<I1*Y*0LY)7\A[=ZVNBU3P>P(N#@Z3W?)-CEP(HV?'/\UP6E=JO
MTWT+]$;(_\M9;J]WBI:(6E_"C%<NZF:MID:T6&B2@L!530_;9IU6J\-59E+]
M^B@[':\HP*OZ&BNO9&Y$D%&B'B?0;[:XW9'8.8%7"U-VIOLHK]H[T5?MFLU@
MV&FD.8@16Q/\[\P VBKWDUFOM!;/C]H<[VEY3*<E/P7]!$@COP)Q=_],WGUL
M(>6C,Z?CBLA%=B(/EZ"SY,[9\OEB54;3&Q#M[5HFLF&G[%"I"ZY8:)72/_EJ
ML[96L)#<*JA.XU1,OXA'J]9AA3LN>IHJ2#!E%_&#@\+E%+_]U,HCLC%3]]D5
M>>AY!\N=2)(%U4;3@-Q .4+)S,%]/E,?$_5'UWIS!$(D0=]?_RN_I^+L]_?1
M&R\Y2#UK0E^"WZ$)_"-GZ\%)K;L03-]\F4[K%KHEN][V(2?B)^S^>.X8^MAI
MC&A:-_"1^CH8C-Q&SF_>P9%3@ 84A2,]TAH5.'2*]ZJ"^X"T,BJ*[_P]6A&Z
M3_%Q94P!Z)R4_6Q&*Z,]P?G5.;D2[8!!A&]2(L<YS:/KX%,P>-SDCS-XRA?(
MJ<HW)1@FFF&C8!I:0]%Q+-$'1^%X)#"?-^6YY))[_VPA<M0^Q3O2F'>'=BST
MQ#<:^O([#SW[6/!#QDS()\Y<2J9C<1:=N:BPIJ*/9,?*'!GSZ2V<Y7+=5HKQ
M?^=BA5TK-=&MOV02+U4!70L-E<[4OJPN%,?=5I#IG^G$=\SD?/I38GIAHW:V
MNCB(X5Y,=F&K^:MC81:CI9A/Z5P5[NG'_.%=E4>U]5>+CN7Q%JZ:2;]S^^B,
MN58,GMKA[@N/5I(9&Q?"K$I+  ,I%=;389"""84%'G3V4P<<#P"@D1<40&*T
M_2ZW40$[[T+NS',6.]RS)/[BW&-4=Z%/FF>(Q> Z1K-KCPK):US)_\:Z,&N/
MWK"]3<;@1C1 ;XW%PFMR0^G2.=-WG[.V?5H"XW<.W,9>.;-[)9OR#;B1=(,W
MEV_&Z^5WQOS:IA7\$#T&##(#O D>R'(<M<HH%$^M_TP=RP?OQ0ZAT6<#E0W0
MN4J" 0(("NXFV]^4<G7O17+P_3K#\-[Z]^+1AV1P%?S9=P<]P'/HL\&US[+
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M6%F->'VMU85"8*/^=,].<%T_::4D$[^D,*?DH4UCBYS$9]*>0ZT!%LG(G<)
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MR!0  !Y  F=U-OP3)T!&0K2'MF(V")\S'U<=5:PUN3:\ :F @(Q.3L%Z+JF
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M*&WPYL^"P. L*9)?5=YDQG>;RIT,*ME+Y(([[QP>^AI/-QD3^O4QZSQ'/EQ
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MCO\ #E"0#-ZK,8OI$2(#' =^3@#A[ =^OBWA#Z-!XS+5HD@ C"_1!)5@H$;
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MZZX##/PF^<?^UW-B#8Y@H(G9@:A@_\L<+8#:Q'1:C)RWY!$#_LY@E1P=RVX
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MX<AB:O1!^(9,=&?*0N>0N#KR$$5LN#YFC<"A, >BTB)?9BH91>3F\_H*Q<D
M4FV?KO"_;J@7R!\ITMA)I!SI&3BR=TP>1YSE$QW&/'?R/ID0G%K6/^1^7B1C
M+TYTS%(I('-)RAYG3W(I0BG%"7$@IX52Z>2KYQ<L/BY).YY\J%D,?1ENC K]
M;4'CP/?[=]:)";$ #'[];]&]RRJ$<'_F]\2QWYX..>PNK-CO721U"5'4^GTR
M?B6BPH>,)*[3Z&B+BJ*37@D%)](N<N#@G<@5NLJK9DJ+-DEV-OFJPQ"?]7,0
MC.ATGRB-6J&VT&7+4WYA./X"Y_;UW=U7'+=O7_*C>UQ59I:9_Y9@*X3*ZZ.,
MR-^IJ;JI,^"N.E)+FC47H8]H","K?+'%]6H6C7%3:[/47CZ*RW/3F0=3X8=)
MLM'I&2XD3G/I"93KK]V)GK@9C+HEWC0;P+4D(;88\9P8WG,9?W0W8?ACPN%N
M*O#'5,+=3.&/&0_4'?#UFTD=2'R*I!ME"&CA#E#[8:'Y?A3D;L*Y;FDH9\FP
M8%G;8I5+:IW&;?$!8#/38K/,/:3-;:?YW:#PC_E>BP/'B-WG$_LSH E:LL.'
M5@K">Q@*#WL2GF4:Q!'M%N<][G?(0<Z8N._@@RB*2)?U6UUU[_NJ-SSB-]R0
M!CPQUT7'^SPJ>;P*LWUJ>3Q:6WU[>3S26BGT^OT4/'P5[O$2[NL://P&LP81
MV@+V6L6)'D"C/##$GAZ?/2^MH^45'D)4/4,5L$>5\E*)MT^&S6$ZR--\VQ#"
M'D@Z-B-FQB,R>0]H)L/W#"(5, ^Z>6,^QL<TRD17MMU:D1\T]YT ",_OH.17
M^0:WZE,<7KD7(_/<;+H?#QS7E59S"5TDXB=EGO=3G:U2>HVY=/8"+$LE3$I#
MC\T-@QZY/QT;5.31_76EI](YUPN#'4TUUU_]UI1U/)V1"1VRN$1(NOZ0_!33
M*VL*\R<O3/?QLX%%HK%%ZEZQ=5B[@?2^39P7F*4,;@<SL]12A_0[?IQ]DD.J
M7*M&S?CO%Q05YW\C-5Z-%/KQ0F>/@8ZHJ7_SL,C1\Y#^!@ M)+SY,HP_%@0\
M<B>VVZ069+X<V-9X!3>4R:Z79,4C?4+Y'G63G4=)C#T<!UA$SJ%_NN<4^*=6
M +>!Z<C9V?P4ED&P6EZ)*&>[6]'[MZUV)\\G+1T?VH%$_'$?\+O@(ZVGL'%D
M0UY7+561 -;?]*.D+2G_)/OZRN/0HM%W%LN^VVPA:!CFEZ9I9IH5,;)=ZVBE
M>@W:<V/@VW>L&>;9OAB#G4C"/D^Z#Y_;@WT_!Y6GB12QN!@9$)=E9I@48M[A
M%5A^Z!D./F3&T96T@ 7C%8:;6V]WK6/XERT?16@%+2IZC[$6+%"';UQW.=Z<
M+U!'/<R95\C=EA?W>'1]5?0:,_5[C_&<!K*TMB[\QD+SOP"V(DG=L)L&6,>=
M)7>F@#!-V' *G)CE0YL,Q:>*FN2Q9SY-T!-4C.2+'IM(GA!8OG".LJ 8X53]
M:FAHUAM^47JHR==ZUXLHV,MFL-, >A+_>U9TYNWT<<0K6<%$2H9<2\$HV-!K
MRDT:F';6BSZNY9!Y?KX $[S<2Z=P\>"CQ4B\Y>'3OAMJN5UVO1/2N^/G(19F
M(>EBNHC1Q^U3"MLK/(F-:;\,SI?*H=7,3(9<#=??9'CUL<W,SB[_/.R?1G36
M?O>#8NXK.N\OJ.\+._ S8I^5(4:HWWW2$!$!CK&+H6T(;SP;D'$!Z>MK/Z67
MB:M[O_=GYQR://@#1(($#QX(%$@084*%"QDV=,@00D2)$RE6M'@18\4K #AV
M]/@19$B1(TF6-'D294J4 1)4I$'C(DR+,C/6A$#3)4:<,6VZW-D3:%"A0XD6
M-7H4:=*>-&;(_SB  &I4J5.I5K5Z%6M6K5NY=O7Z=:O!!%/%EC5[UF!!LP_9
MMG7+5FE<B@=4UK5[%V]>O1Q;4OR9\:5<P8,)%S9\&'%BN5ZN/ 7[&')DR9,I
MAQT+52P"M)LYEU5[\/-;T:,;*@X*<P;=O:M9MW8],L&,E[-IU[9]&W=NW;MY
M]_;]&WAPX<.)%S=^'#GQ&8P/-'<.U7ETZ=.?(X@.O?IUZ]6W.^X>M;E4[^"G
MCJ]\'CWZ!"VD"I1:,.I ]YH)IJU_<,;]!_G5[N??<(;_ OS//X0&-#! ! 5D
MBC_:'J@M(MINFFV&+EZ[$,,,ZT* A00'_!!$_O(+D<01_2LQP!907/^1Q19=
M?!'&&&6<D<8:;2R1(!,/1/'$$/?[L4</80PR0!:NL"( &;KHXHH5#E"2R0.2
M#"3* UA8LK$GL6P.RBR[Y')++:O\4DPOPR03S26M:,Z*,-NL\@HWY80SS#CI
MO#-+._/<<@4[4SO SC4![2*0/ 6A4Y#&$(@S418&%40&#KL0Q(L9H.K"BTHE
MS=12!# 5Q-(K.67!4TXWK90%44'E,%--66@UU$Q!3156%F2H]=51;]6UUETK
ME<'7II;C5(9A45T.D;U6 &#993MREMEG5X#V69"H979:CIKUJ-ENM;U6PY+
M#9?<<LT]%]UTU7WM22N<?3*&=VUU=@5WWY7_@05Z\=4W7VWWU395>@/VMU]F
M9<C68(2G/=A?A0_65^%I]64X87KCI5?B;R/>&&.%XU5-8I"G%=E)C45V%. 5
M O@696Q+9C;5E6%F0>9I:=:XYGQSOCD FW?^&>";L15:XIQ5YBA5HE?@N>B@
M:YYVY9['79?JJCE2 >NLM=Z:ZZZ]=L+KL,4>F^RRS3X;[;357IOMMMU^&^ZR
MJP $D"HXFKONNP$)Q&X \.[;"KK[QOL)C@('I'"_]<@;@,,'ISOQPQ/'V]G
M]2B<!,))($%R #*G>UG.(=^<<A)4.#QTU#>W_ G3\5;!=#UD;UV%*F8W/0]
M+L=Z;CW 5D%V/;"V_YKXXHT_'GF[JAB%^>:=?Q[ZZ*6?GOKJK;\>^^RUWY[[
M[KW_'OSPQ?>>E#RJ.'_:\\_G7?WTU5?A"?6K6"%^]9^H__S[;<\?_RKTK\)\
M_[.?[?3@O_CEH8 'S(/Y_+= !@)P@>ISH 3S\ <&+A 0#M1=!C%(-PUZ<(%_
MH)L%<P<(4OP!A:10(0K_0(I1N#"%*B2%[I)70QO>$(?F<D(G1L'#YHD"B**
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M07GQH +QDB"V=HTG)U5 _UZ_@A*\?R@O7<'+O(E"%L !%C!)OVM7)Y" KDY
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M;K!F<5(1>$1Q%2W1O 2'D%9QQ&B1D.@F@V[1A"H)%Z>,;LKG%E7HR4P(&*F
M&.^)"O]D"!F5$928,0]*H1"C\2,>RG"JB\A>K2/@BEFJ*_TVQQM#(J&D41S'
M<2^\,7.HT:'HI<BV<7ZT!7VT91W3$1[1T0K:<1NI\0GB<1WK1QWQL0JLP/P
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M2=$/6NCE(ZX%8;!%8U951+VKS!YLJ&C-O#",P]8+O2Z,Y7"-O&BMOG1-P:@
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M8/$7?3&]@Q$8D4T8"4D9XRR^%2R^$V>W\[MJ;)F7^]N__QO G7"0"@E^JM#
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M*J,V>C$T6J,W:FL! 0 [4$L#!!0    ( -*#>U<X!<9ATED  /):   -
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M_G/FP6H>S^5^U"2P:K:*WBT+N^DO<>%)'G-7-1\+*:M3 #KY(R )TP4!DT.
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M/?)OSV#2FZIZ'L -%0$=]Y7;C;E79U6WC*DB+?;;#]71;K[CKN4B#Z7[=H"
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MJVD90SP[NGC 8#0G8YXZ;5G[,Z.4Q.Q6PA9%#< Q%UZWT"/S<Y!-;/QT2'I
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M)9O$:,E;C]3)&H@C =S*'5^5J<W'U<:2K,Y;QC*QZ %53-#ZY?Y1'LR5.&5
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MUQ'V7YL.Z"@ D?\ 4$L! A0#%     @ TH-[5TFJ& 2Q#   TXH  !$
M         ( !     &%V>&PM,C R,S Y,S N>'-D4$L! A0#%     @ TH-[
M5SFZRQ4;"P  NH$  !4              ( !X P  &%V>&PM,C R,S Y,S!?
M8V%L+GAM;%!+ 0(4 Q0    ( -*#>U>;^G@%.!@  /"# 0 5
M  "  2X8  !A=GAL+3(P,C,P.3,P7V1E9BYX;6Q02P$"% ,4    " #2@WM7
M&5U%G1I$  "M[0, %0              @ &9,   879X;"TR,#(S,#DS,%]L
M86(N>&UL4$L! A0#%     @ TH-[5X1K3H_7+0  A  # !4
M ( !YG0  &%V>&PM,C R,S Y,S!?<')E+GAM;%!+ 0(4 Q0    ( -*#>U<O
M!2QI9Q8# %!W(0 -              "  ?"B  !E-3(T,%\Q,&LN:'1M4$L!
M A0#%     @ TH-[5R>?P610<0  Q%\" !               ( !@KD# &4U
M,C0P7V5X,30M,2YH=&U02P$"% ,4    " #2@WM7->SR,DL"   G"@  $
M            @ $ *P0 934R-#!?97@R,2TQ+FAT;5!+ 0(4 Q0    ( -*#
M>U>?WR*8W0(  (8)   0              "  7DM! !E-3(T,%]E>#(S+3$N
M:'1M4$L! A0#%     @ TH-[5R:'[)+8 @  P@T  !               ( !
MA# $ &4U,C0P7V5X,C,M,BYH=&U02P$"% ,4    " #2@WM7E,&! JX(   1
M10  $               @ &*,P0 934R-#!?97@S,2TQ+FAT;5!+ 0(4 Q0
M   ( -*#>U>>/>.GP0@   %#   0              "  68\! !E-3(T,%]E
M>#,Q+3(N:'1M4$L! A0#%     @ TH-[5US.;DBS!@  QB(  !
M     ( !544$ &4U,C0P7V5X,S(M,2YH=&U02P$"% ,4    " #2@WM73B-.
MPN87   9CP  $               @ $V3 0 934R-#!?97@Y-RTQ+FAT;5!+
M 0(4 Q0    ( -*#>U>?C:M$D6,  (1D   -              "  4ID! !I
M;6%G95\P,#$N9VEF4$L! A0#%     @ TH-[5S@%QF'260  \EH   T
M         ( !!L@$ &EM86=E7S P,BYG:6902P4&     !  $ #L P   R(%
#

end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
