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Income Taxes - Reconciliation of the income tax expense (Details)
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Income Taxes    
Federal statutory income tax rate 21.00% 21.00%
State income taxes, net of federal benefit 6.40% 3.40%
Change in valuation allowance (32.30%) (26.40%)
IP transfer (0.30%)  
Research and development tax credits 4.90% 8.80%
Foreign tax rate differential 0.20% (7.60%)
Other adjustments (0.20%)  
Effective income tax rate (0.30%) (0.80%)