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Significant Accounting Policies (Tables) | 3 Months Ended | 10 Months Ended | 12 Months Ended
--- | --- | --- | ---
Mar. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2021
Schedule of calculation of basic and diluted net income (loss) per ordinary share | The following table sets forth the calculation of basic and diluted earnings per share for the periods indicated based on the weighted average number of common shares outstanding:
|  | Three Months Ended March 31, |
|  | 2022 |  |  | 2021 |
Numerator |  |  |  |  |  |  |  |
Net loss available to Class A Unit holders |  | $ | (67,486 | ) |  | $ | (11,609 | )
Denominator |  |  |  |  |  |  |  |
Weighted average Class A Units outstanding, basic and diluted |  |  | 186,500,000 |  |  |  | 122,111,111 |
Net loss per Class A Unit |  |  |  |  |  |  |  |
Net loss per Class A Unit, basic and diluted |  | $ | (0.36 | ) |  | $ | (0.10 | )
|  | The following table sets forth the calculation of basic and diluted earnings per share for the periods indicated based on the weighted average number of common shares outstanding:
|  | Years Ended December 31, |
|  | 2021 |  |  | 2020 |
Numerator |  |  |  |  |  |  |  |
Net loss available to Class A Unit holders |  | $ | (55,146 | ) |  | $ | (26,749 | )
Denominator |  |  |  |  |  |  |  |
Weighted average Class A Units outstanding, basic and diluted |  |  | 150,706,849 |  |  |  | 104,986,301 |
Net loss per Class A Unit |  |  |  |  |  |  |  |
Net loss per Class A Unit, basic and diluted |  | $ | (0.37 | ) |  | $ | (0.25 | )
Schedule of accrued expenses | Accrued expenses as presented in the Condensed Consolidated Balance Sheets as of March 31, 2022 and December 31, 2021 consisted of the following (in thousands):
|  | March 31, 2022 |  |  | December 31, 2021 |
Compensation |  | $ | 818 |  |  | $ | 1,832 |
Clinical study related costs |  |  | 653 |  |  |  | 2,031 |
Accrued legal |  |  | 3,095 |  |  |  | 964 |
Manufacturing improvement costs |  |  | 3,137 |  |  |  | 4,164 |
Other accrued expenses |  |  | 414 |  |  |  | 222 |
Total accrued expenses and other |  | $ | 8,117 |  |  | $ | 9,213 |
|  | Accrued expenses which have been presented on the consolidated balance sheets as of December 31, 2021 and 2020 consisted of the following (in thousands):
|  | December 31, 2021 |  |  | December 31, 2020 |
Compensation |  | $ | 1,832 |  |  | $ | 1,085 |
Clinical study related costs |  |  | 2,031 |  |  |  | 1,154 |
Facility expansion costs |  |  | 19 |  |  |  | 1,709 |
Accrued legal |  |  | 964 |  |  |  | — |
Manufacturing improvement costs |  |  | 4,164 |  |  |  | — |
Other accrued expenses |  |  | 203 |  |  |  | 548 |
Total accrued expenses and other |  | $ | 9,213 |  |  | $ | 4,496 |
Schedule of estimated useful lives | The estimated useful lives are as follows:
Computer equipment and software |  | 3-5 years
Furniture and equipment |  | 5-7 years
Leasehold improvements |  | remainder of lease term
|  | The estimated useful lives are as follows:
Computer equipment and software |  | 3- 5 years
Furniture and equipment |  | 5- 7 years
Leasehold improvements |  | remainder of lease term
Schedule of fixed assets | Fixed assets consisted of the following (in thousands):
|  | March 31, 2022 |  |  | December 31, 2021 |
Furniture and equipment |  | $ | 2,220 |  |  | $ | 2,180 |
Computer equipment and software |  |  | 589 |  |  |  | 569 |
Leasehold improvements |  |  | 10,520 |  |  |  | 10,517 |
Construction in progress |  |  | 631 |  |  |  | 351 |
Less: accumulated depreciation |  |  | (2,857 | ) |  |  | (2,259 | )
Total fixed assets, net |  | $ | 11,103 |  |  | $ | 11,358 |
|  | Fixed assets consisted of the following (in thousands):
|  | December 31, 2021 |  |  | December 31, 2020 |
Furniture and equipment |  | $ | 2,180 |  |  | $ | 2,011 |
Computer equipment and software |  |  | 569 |  |  |  | 130 |
Leasehold improvements |  |  | 10,517 |  |  |  | 76 |
Construction in progress |  |  | 351 |  |  |  | 7,854 |
Less: accumulated depreciation |  |  | (2,259 | ) |  |  | (1,157 | )
Total fixed assets, net |  | $ | 11,358 |  |  | $ | 8,914 |
Schedule of intangible asset | The following table summarizes information related to the Company’s assembled workforce intangible asset (in thousands):
|  | March 31, 2022 |  |  | December 31, 2021 |
Gross carrying amount |  | $ | 1,073 |  |  | $ | 1,073 |
Accumulated amortization |  |  | 699 |  |  |  | 645 |
Net carrying amount |  | $ | 374 |  |  | $ | 428 |
|  | The following table summarizes information related to the Company’s assembled workforce intangible asset (in thousands):
|  | December 31, 2021 |  |  | December 31, 2020 |
Gross carrying amount |  | $ | 1,073 |  |  | $ | 1,073 |
Accumulated amortization |  |  | 645 |  |  |  | 431 |
Net carrying amount |  | $ | 428 |  |  | $ | 642 |
Social Capital Suvretta Holdings Corp. III [Member] |  |  |
Schedule of calculation of basic and diluted net income (loss) per ordinary share | At March 31, 2022 and December 31, 2021, the Class A ordinary shares subject to possible redemption reflected in the condensed balance sheets are reconciled in the following table:
Gross proceeds |  | $ | 250,000,000 |
Less: |  |  |  |
Class A ordinary shares issuance costs |  |  | (12,479,666 | )
Plus: |  |  |  |
Accretion of carrying value to redemption value |  |  | 12,487,990 |
Class A ordinary shares subject to possible redemption, December 31, 2021 |  |  | 250,008,324 |
Plus: |  |  |  |
Remeasurement of carrying value to redemption value |  |  | (8,324 | )
Class A ordinary shares subject to possible redemption, March 31, 2022 |  | $ | 250,000,000 |
| At December 31, 2021, the Class A ordinary shares subject to possible redemption reflected in the balance sheet are reconciled in the following table:
Gross proceeds |  | $ | 250,000,000 |
Less: |  |  |  |
Class A ordinary shares issuance costs |  |  | (12,479,666 | )
Plus: |  |  |  |
Increase of carrying value to redemption value |  |  | 12,487,990 |
Class A ordinary shares subject to possible redemption |  | $ | 250,008,324 |
Schedule of Class A Ordinary shares reflected in the Balance Sheets | The following table reflects the calculation of basic and diluted net loss per ordinary share (in dollars, except per share amounts):
|  | For the Three Months Ended March 31, 2022 |  |  | For the Period from February 25, 2021 (Inception) Through March 31, 2021 |
|  | Class A |  |  | Class B |  |  | Class A |  |  | Class B |
Basic and diluted net loss per ordinary share |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Numerator: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Allocation of net loss |  | $ | (3,200,799 | ) |  | $ | (780,226 | ) |  | $ | — |  |  | $ | (5,182 | )
Denominator: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Basic and diluted weighted average shares outstanding |  |  | 25,640,000 |  |  |  | 6,250,000 |  |  |  | — |  |  |  | 5,500,000 |
Basic and diluted net loss per ordinary share |  | $ | (0.12 | ) |  | $ | (0.12 | ) |  | $ | — |  |  | $ | (0.00 | )
| The following table reflects the calculation of basic and diluted net loss per ordinary share (in dollars, except per share amounts):
|  | For the Period from February 25, 2021 (Inception) Through December 31, 2021 |
|  | Class A |  |  | Class B |
Basic and diluted net loss per ordinary share |  |  |  |  |  |  |  |
Numerator: |  |  |  |  |  |  |  |
Allocation of net loss |  | $ | (1,675,346 | ) |  | $ | (649,283 | )
Denominator: |  |  |  |  |  |  |  |
Basic and diluted weighted average shares outstanding |  |  | 15,101,877 |  |  |  | 5,852,751 |
Basic and diluted net loss per ordinary share |  | $ | (0.11 | ) |  | $ | (0.11 | )

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