XML 69 R58.htm IDEA: XBRL DOCUMENT v3.25.1
COMMITMENTS AND CONTINGENCIES - Narrative (Details)
$ in Thousands
 1 Months Ended 3 Months Ended 12 Months Ended
Dec. 22, 2022
USD ($)
quarterly_payment
Feb. 10, 2021
Mar. 11, 2020
Dec. 31, 2024
USD ($)
Jun. 30, 2021
USD ($)
Mar. 31, 2025
USD ($)
Mar. 31, 2024
USD ($)
Jun. 30, 2021
USD ($)
Dec. 31, 2024
USD ($)
Commitments And Contingencies [Line Items]                  
Contract cost incurred in research and development activities           $ 42,200      
Supply Agreement, Patheon Inc.                  
Commitments And Contingencies [Line Items]                  
Purchase commitment, option for non-auto renewal, prior written notice period     18 months            
Minimum purchase commitment           1,100      
Siegfried Evionnaz SA                  
Commitments And Contingencies [Line Items]                  
Cost of purchased minimum quantity product           15,600      
Long-term minimum purchase commitment           3,600     $ 3,600
STA Pharmaceutical Hong Kong Limited                  
Commitments And Contingencies [Line Items]                  
Long-term minimum purchase commitment           6,100      
WuXi STA                  
Commitments And Contingencies [Line Items]                  
Long-term minimum purchase commitment           900      
Purchase commitment, option to extend, prior notice period   18 months              
Long-term purchase commitment, option to terminate, prior notice period (at least)   180 days              
Esteve                  
Commitments And Contingencies [Line Items]                  
Long-term minimum purchase commitment           7,600      
BioVectra Inc                  
Commitments And Contingencies [Line Items]                  
Long-term purchase commitment, termination amount payable $ 32,500                
Long-term purchase commitment, upfront payment termination amount $ 17,500                
Long-term purchase commitment, termination amount payable after upfront payment, number of quarterly periods | quarterly_payment 6                
Long-term purchase commitment, termination amount payable after upfront payment, per quarter $ 2,500                
Long-term purchase commitment, termination amount payable after upfront payment $ 15,000                
Long-term purchase commitment, imputed interest on termination amount payable 17.00%                
Long-term purchase commitment, upfront termination amount classified as cost of goods sold $ 11,200                
Amortization discount           200 $ 500    
Panion & BF Biotech, Inc | License Agreement                  
Commitments And Contingencies [Line Items]                  
Royalty payments           $ 2,600 $ 1,900    
Cyclerion | License Agreement                  
Commitments And Contingencies [Line Items]                  
Expiration period beginning with first commercial sale           10 years      
Termination period, prior written notice (in days)           180 days      
Cyclerion | License Agreement | Acquired Licenses                  
Commitments And Contingencies [Line Items]                  
Upfront payments               $ 3,000  
Cyclerion | License Agreement | Acquired Licenses | Research and Development Expense                  
Commitments And Contingencies [Line Items]                  
Upfront payments         $ 3,000        
Cyclerion | Cyclerion Amendment | Acquired Licenses                  
Commitments And Contingencies [Line Items]                  
Upfront payments       $ 1,250          
Contingent consideration       $ 500         500
Specified development and regulatory milestone payments, contingent on a product-by-product basis           $ 198,500      
Cyclerion | Cyclerion Amendment | Acquired Licenses | Maximum                  
Commitments And Contingencies [Line Items]                  
Tiered royalties           20.00%      
Cyclerion | Cyclerion Amendment | Acquired Licenses | Research and Development Expense                  
Commitments And Contingencies [Line Items]                  
Upfront payments                 1,250
Contingent consideration                 $ 500