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Segment Information | 6 Months Ended
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May 31, 2026
Segment Reporting [Abstract] |
Segment Information | Segment Information The Company operates and manages its business as a single reportable and operating segment. The Company is in the business of discovery, development and commercialization of innovative targeted protein degradation medicines aimed at improving treatment options for patients with cancer and inflammatory diseases. The Company’s CODM is the Chief Executive Officer, who reviews and evaluates net loss to monitor budget versus actual results and to analyze cash flows for purposes of allocating resources and assessing financial performance. The measure of segment assets is reported on the balance sheet as total assets. All of the Company's long-lived assets are located in the United States and all of the Company's revenue was derived from customers located in the United States. The Company does not allocate internal costs by product candidate. With respect to internal costs, several departments support multiple product candidate research and development programs, and therefore the costs cannot be allocated to a particular product candidate or development program. In addition to the significant expense categories included within net loss presented in the Company's statements of operations, disaggregated research and development expenses are as follows (in thousands):
| Three Months Ended May 31, |  | Six Months Ended May 31,
| 2026 |  | 2025 |  | 2026 |  | 2025
External clinical development expenses: |  |  |  |  |  |  |
Bexobrutideg (NX-5948) | $ | 28,192 |  |  | $ | 18,558 |  |  | $ | 52,166 |  |  | $ | 34,278 |
Zelebrudomide (NX-2127) | 1,167 |  |  | 1,559 |  |  | 3,073 |  |  | 2,665 |
NX-1607 | 1,738 |  |  | 2,332 |  |  | 2,926 |  |  | 4,292 |
Internal research and development expenses | 56,556 |  |  | 55,647 |  |  | 113,624 |  |  | 106,524 |
Total research and development expenses | $ | 87,653 |  |  | $ | 78,096 |  |  | $ | 171,789 |  |  | $ | 147,759 |

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