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Condensed Consolidated Statements of Convertible Preferred Stock and Stockholders' Equity (Deficit) (Unaudited) - USD ($) $ in Thousands | Total | Convertible Preferred Stock | Series B Convertible Preferred Stock | Common Stock | Additional Paid-in Capital | Accumulated Other Comprehensive Income (Loss) | Accumulated Deficit
--- | --- | --- | --- | --- | --- | --- | ---
Beginning balance at Dec. 31, 2018 | $ (179,177) |  |  | $ 1 | $ 14,672 | $ (14) | $ (193,836)
Beginning balance (in shares) at Dec. 31, 2018 |  | 69,910,520 |  |  |  |  |
Beginning balance at Dec. 31, 2018 |  | $ 309,137 |  |  |  |  |
Beginning balance (in shares) at Dec. 31, 2018 |  |  |  | 8,858,799 |  |  |
Issuance of convertible preferred stock, net of issuance cost |  |  | $ 327,475 |  |  |  |
Issuance of convertible preferred stock, net of issuance cost (in Shares) |  |  | 18,202,213 |  |  |  |
Issuance of common stock in connection with a license agreement | 617 |  |  |  | 617 |  |
Issuance of common stock in connection with a license agreement (in shares) |  |  |  | 38,888 |  |  |
Repayment of promissory notes, net of unvested common stock | 1,355 |  |  |  | 1,355 |  |
Repayment of promissory notes, net of unvested shares (in shares) |  |  |  | 1,390,925 |  |  |
Vesting of restricted common stock | 119 |  |  |  | 119 |  |
Vesting of restricted common stock (in shares) |  |  |  | 733,041 |  |  |
Exercise of stock options | 1,066 |  |  |  | 1,066 |  |
Exercise of stock option (in shares) |  |  |  | 706,579 |  |  |
Stock-based compensation | 6,040 |  |  |  | 6,040 |  |
Other comprehensive income (loss) | 95 |  |  |  |  | 95 |
Net loss | (110,912) |  |  |  |  |  | (110,912)
Ending balance at Sep. 30, 2019 | (280,797) |  |  | $ 1 | 23,869 | 81 | (304,748)
Ending balance (in shares) at Sep. 30, 2019 |  | 88,112,733 |  |  |  |  |
Ending balance at Sep. 30, 2019 |  | $ 636,612 |  |  |  |  |
Ending balance (in shares) at Sep. 30, 2019 |  |  |  | 11,728,232 |  |  |
Beginning balance at Jun. 30, 2019 | (236,967) |  |  | $ 1 | 19,226 | 240 | (256,434)
Beginning balance (in shares) at Jun. 30, 2019 |  | 88,112,733 |  |  |  |  |
Beginning balance at Jun. 30, 2019 |  | $ 636,612 |  |  |  |  |
Beginning balance (in shares) at Jun. 30, 2019 |  |  |  | 9,722,838 |  |  |
Issuance of common stock in connection with a license agreement | 617 |  |  |  | 617 |  |
Issuance of common stock in connection with a license agreement (in shares) |  |  |  | 38,888 |  |  |
Repayment of promissory notes, net of unvested common stock | 1,355 |  |  |  | 1,355 |  |
Repayment of promissory notes, net of unvested shares (in shares) |  |  |  | 1,390,925 |  |  |
Vesting of restricted common stock | 119 |  |  |  | 119 |  |
Vesting of restricted common stock (in shares) |  |  |  | 337,075 |  |  |
Exercise of stock options | 364 |  |  |  | 364 |  |
Exercise of stock option (in shares) |  |  |  | 238,506 |  |  |
Stock-based compensation | 2,188 |  |  |  | 2,188 |  |
Other comprehensive income (loss) | (159) |  |  |  |  | (159) |
Net loss | (48,314) |  |  |  |  |  | (48,314)
Ending balance at Sep. 30, 2019 | (280,797) |  |  | $ 1 | 23,869 | 81 | (304,748)
Ending balance (in shares) at Sep. 30, 2019 |  | 88,112,733 |  |  |  |  |
Ending balance at Sep. 30, 2019 |  | $ 636,612 |  |  |  |  |
Ending balance (in shares) at Sep. 30, 2019 |  |  |  | 11,728,232 |  |  |
Beginning balance at Dec. 31, 2019 | $ 423,942 |  |  | $ 11 | 793,051 | (601) | (368,519)
Beginning balance (in shares) at Dec. 31, 2019 | 107,648,925 |  |  | 107,648,925 |  |  |
Reclassification of derivative liability to additional paid-in capital | $ 29,245 |  |  |  | 29,245 |  |
Issuance of common stock in connection with the achievement of a milestone (in shares) |  |  |  | 1,111,111 |  |  |
Issuance of common stock in connection with a collaboration agreement | 206,699 |  |  | $ 1 | 206,698 |  |
Issuance of common stock in connection with a collaboration agreement (in shares) |  |  |  | 6,626,027 |  |  |
Issuance of common stock for cashless exercise of warrant (in shares) |  |  |  | 211,774 |  |  |
Issuance of common stock in connection with a follow-on offering | 323,214 |  |  | $ 1 | 323,213 |  |
Issuance of common stock in connection with a follow-on offering (in shares) |  |  |  | 8,214,285 |  |  |
Vesting of restricted common stock | 1,316 |  |  |  | 1,316 |  |
Vesting of restricted common stock (in shares) |  |  |  | 1,791,880 |  |  |
Exercise of stock options | 3,540 |  |  |  | 3,540 |  |
Exercise of stock option (in shares) |  |  |  | 1,387,629 |  |  |
Stock-based compensation | 17,299 |  |  |  | 17,299 |  |
Other comprehensive income (loss) | 116 |  |  |  |  | 116 |
Net loss | (193,016) |  |  |  |  |  | (193,016)
Ending balance at Sep. 30, 2020 | $ 812,355 |  |  | $ 13 | 1,374,362 | (485) | (561,535)
Ending balance (in shares) at Sep. 30, 2020 | 126,991,631 |  |  | 126,991,631 |  |  |
Beginning balance at Jun. 30, 2020 | $ 563,779 |  |  | $ 12 | 1,040,988 | (295) | (476,926)
Beginning balance (in shares) at Jun. 30, 2020 |  |  |  | 117,727,086 |  |  |
Issuance of common stock in connection with a follow-on offering | 323,214 |  |  | $ 1 | 323,213 |  |
Issuance of common stock in connection with a follow-on offering (in shares) |  |  |  | 8,214,285 |  |  |
Vesting of restricted common stock | 427 |  |  |  | 427 |  |
Vesting of restricted common stock (in shares) |  |  |  | 561,255 |  |  |
Exercise of stock options | 1,152 |  |  |  | 1,152 |  |
Exercise of stock option (in shares) |  |  |  | 489,005 |  |  |
Stock-based compensation | 8,582 |  |  |  | 8,582 |  |
Other comprehensive income (loss) | (190) |  |  |  |  | (190) |
Net loss | (84,609) |  |  |  |  |  | (84,609)
Ending balance at Sep. 30, 2020 | $ 812,355 |  |  | $ 13 | $ 1,374,362 | $ (485) | $ (561,535)
Ending balance (in shares) at Sep. 30, 2020 | 126,991,631 |  |  | 126,991,631 |  |  |

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- Definition Total of all stockholders' equity (deficit) items, net of receivables from officers, directors, owners, and affiliates of the entity which are attributable to the parent. The amount of the economic entity's stockholders' equity attributable to the parent excludes the amount of stockholders' equity which is allocable to that ownership interest in subsidiary equity which is not attributable to the parent (noncontrolling interest, minority interest). This excludes temporary equity and is sometimes called permanent equity. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 235 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.4-08(g)(1)(ii)) -URI http://asc.fasb.org/extlink&oid=120395691&loc=d3e23780-122690 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 310 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SAB Topic 4.E) -URI http://asc.fasb.org/extlink&oid=27010918&loc=d3e74512-122707 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(31)) -URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(29)) -URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(30)) -URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 Reference 6: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 825 -SubTopic 10 -Section 50 -Paragraph 28 -Subparagraph (f) -URI http://asc.fasb.org/extlink&oid=75031198&loc=d3e14064-108612 Reference 7: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 323 -SubTopic 10 -Section 50 -Paragraph 3 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=114001798&loc=d3e33918-111571 + Details
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- Definition Carrying amount, attributable to parent, of an entity's issued and outstanding stock which is not included within permanent equity. Temporary equity is a security with redemption features that are outside the control of the issuer, is not classified as an asset or liability in conformity with GAAP, and is not mandatorily redeemable. Includes any type of security that is redeemable at a fixed or determinable price or on a fixed or determinable date or dates, is redeemable at the option of the holder, or has conditions for redemption which are not solely within the control of the issuer. Includes stock with a put option held by an ESOP and stock redeemable by a holder only in the event of a change in control of the issuer. + References No definition available. + Details
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- Definition The number of securities classified as temporary equity that have been issued and are held by the entity's shareholders. Securities outstanding equals securities issued minus securities held in treasury. Temporary equity is a security with redemption features that are outside the control of the issuer, is not classified as an asset or liability in conformity with GAAP, and is not mandatorily redeemable. Includes any type of security that is redeemable at a fixed or determinable price or on a fixed or determinable date or dates, is redeemable at the option of the holder, or has conditions for redemption which are not solely within the control of the issuer. If convertible, the issuer does not control the actions or events necessary to issue the maximum number of shares that could be required to be delivered under the conversion option if the holder exercises the option to convert the stock to another class of equity. If the security is a warrant or a rights issue, the warrant or rights issue is considered to be temporary equity if the issuer cannot demonstrate that it would be able to deliver upon the exercise of the option by the holder in all cases. Includes stock with put option held by ESOP and stock redeemable by holder only in the event of a change in control of the issuer. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(27)(b)) -URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 + Details
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- Definition Value of new stock classified as temporary equity issued during the period. + References No definition available. + Details
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- Definition Vested shares related to repayment of promissory notes. + References No definition available. + Details
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- Definition Value of promissory notes related to vested shares. + References No definition available. + Details
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- Definition Stock issued during period shares achievement of milestone. + References No definition available. + Details
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- Definition Stock issued during period shares cashless exercise of warrant. + References No definition available. + Details
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- Definition Number of common stock issued in connection with a license agreement. + References No definition available. + Details
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- Definition Stock issued during period value collaboration agreement. + References No definition available. + Details
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- Definition Value of common stock issued in connection with a license agreement. + References No definition available. + Details
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