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v3.22.2.2

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2022 | Sep. 30, 2021
CASH FLOWS FROM OPERATING ACTIVITIES: |  |
Net income (loss) | $ 617,440 | $ 3,330
Adjustments to reconcile net income (loss) to net cash used in operating activities: |  |
Change in estimated constraint on profit-sharing amount | 353,526 | 0
Depreciation and amortization | 4,431 | 3,891
Amortization of intangible assets | 399 | 399
Accretion of discounts on investments, net | (1,315) | (859)
Noncash lease expense | 6,473 | 4,471
Change in fair value of equity investments | 120,019 | (164,072)
Change in estimated fair value of contingent consideration | 7,890 | 63,246
Payment for contingent consideration in excess of acquisition date fair value | (93,803) | (8,140)
Stock-based compensation | 77,217 | 59,413
Other | 301 | 486
Changes in operating assets and liabilities: |  |
Receivable from collaboration | 491,872 | (93,003)
Prepaid expenses and other current assets | 11,023 | 1,878
Other assets | (3,434) | (1,051)
Accounts payable | (2,003) | (959)
Accrued liabilities and other long-term liabilities | 65,144 | (13,490)
Operating lease liabilities | (2,547) | (383)
Deferred revenue | (24,506) | 89,559
Net cash provided by (used in) operating activities | 1,628,127 | (55,284)
CASH FLOWS FROM INVESTING ACTIVITIES: |  |
Proceeds from sale of an equipment | 22 | 0
Purchases of property and equipment | (55,432) | (8,750)
Purchases of investments | (1,069,752) | (55,729)
Maturities of investments | 84,836 | 301,243
Proceeds from disposal of an equipment | 0 | 4
Net cash (used in) provided by investing activities | (1,040,326) | 236,768
CASH FLOWS FROM FINANCING ACTIVITIES: |  |
Proceeds from issuance of common stock in connection with a grant agreement | 28,462 | 0
Proceeds from issuance of common stock in connection with a collaboration agreement | 0 | 85,213
Payment of principal on financing lease obligation | (183) | (187)
Proceeds from exercise of stock options | 3,602 | 9,635
Issuance of common stock under ESPP | 2,066 |
Payment of contingent consideration | (1,197) | 0
Net cash provided by financing activities | 32,750 | 94,661
Net increase in cash, cash equivalents and restricted cash and cash equivalents | 620,551 | 276,145
Cash, cash equivalents and restricted cash and cash equivalents at beginning of period | 363,415 | 451,487
Cash, cash equivalents and restricted cash and cash equivalents at end of period | 983,966 | 727,632
NONCASH INVESTING AND FINANCING ACTIVITIES: |  |
Common stock issued for payment of contingent consideration | 0 | 1,860
Property and equipment purchases included in accounts payable and accrued liabilities | 6,413 | 4,191
Operating lease liabilities obtained in exchange of right-of-use asset | 3,969 | 90
SUPPLEMENTAL DISCLOSURE OF CASHFLOW INFORMATION |  |
Cash paid during the period for income tax | 191,653 | 0
RECONCILIATION OF CASH, CASH EQUIVALENTS AND RESTRICTED CASH TO THE CONDENSED CONSOLIDATED BALANCE SHEETS: |  |
Cash and cash equivalents | 963,735 | 714,521
Restricted cash and cash equivalents, current | 12,955 | 6,112
Restricted cash and cash equivalents, noncurrent | 7,276 | 6,999
Total cash, cash equivalents and restricted cash | $ 983,966 | $ 727,632

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