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Collaboration revenue (Tables)

9 Months Ended

Sep. 30, 2022

Revenue Recognition [Abstract]

Schedule of Collaboration revenue

During the three and nine months ended September 30, 2022, the Company recorded profit-sharing amounts and profit-sharing amounts constrained as components of collaboration revenue in the unaudited condensed consolidated statements of operations, as follows:

		Three Months Ended September 30,								Nine Months Ended September 30,
		2022				2021				2022				2021
		(in thousands)
Collaboration revenue, net
Profit-sharing amount		$	291,226			$	102,398			$	1,863,374			$	107,731
Profit-sharing amount constrained			(2,431	)			—				(399,864	)			—
Profit-sharing amount previously constrained, released			20,350				—				20,350				—
Total collaboration revenue, net		$	309,145			$	102,398			$	1,483,860			$	107,731

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