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Stock-Based Awards (Tables)

9 Months Ended

Sep. 30, 2022

Summary of Assumptions Used for Estimating the Fair Value of Stock Options Granted

The fair value of stock options granted to employees was estimated on the date of grant using the Black-Scholes option-pricing model with the following assumptions:

		Three Months Ended September 30,								Nine Months Ended September 30,
		2022				2021				2022				2021
Expected term of options (in years)			6.1			5.3 - 6.1				5.3 - 6.1				5.3 - 6.1
Expected stock price volatility		110.6% - 110.8%				106.9% - 111.5%				103.8% - 111.2%				103.1% - 111.5%
Risk-free interest rate		3.0% - 3.6%				0.8% - 1.0%				1.6% - 3.6%				0.6% - 1.2%
Expected dividend yield			—				—				—				—

Summary of Stock-based Compensation Expense

The following table sets forth the total stock-based compensation expense for all awards granted to employees and non-employees and the ESPP in the unaudited condensed consolidated statements of operations:

		Three Months Ended September 30,								Nine Months Ended September 30,
		2022				2021				2022				2021
		(in thousands)
Research and development		$	12,607			$	11,165			$	39,791			$	30,455
Selling, general and administrative			12,207				11,779				37,426				28,958
Total stock-based compensation		$	24,814			$	22,944			$	77,217			$	59,413

X

- Definition

Tabular disclosure of cost recognized for award under share-based payment arrangement by plan. Includes, but is not limited to, related tax benefit.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(1)
-URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901

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X

- Definition

Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (f)(2)
-URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901

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