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Grant Agreements - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands		3 Months Ended		9 Months Ended
	Jan. 13, 2022	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021	Dec. 31, 2021
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accrued and other liabilities		$ 282,616		$ 282,616		$ 236,512
Grant Revenue
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue from grants		3,125	$ 903	7,704	$ 5,356
Human Immunodeficiency Virus ('HIV') Grant | Maximum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Grant awarded amount. maximum		55,700		55,700
Vaccinal Antibody Grant | Grant Revenue
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue from grants		2,800	$ 900	7,400	$ 5,200
Vaccinal Antibody Grant | Bill And Melinda Gates Foundation
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Deferred revenue		24,300		24,300		6,900
Common Stock, Shares Purchased	881,365
Common Stock, Shares Purchased, Share Price	$ 45.38
Common Stock, Shares Purchased , Aggregate Purchase Price	$ 40,000
Common stock, shares issued, fair market value	$ 28,500
Closing stock price	$ 37.65
Underlying shares, Premium received	$ 11,300
Accrued and other liabilities		$ 0		0		$ 1,800
BARDA
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Potential maximum amount of grant				1,000,000
Maximum amount of grant during the base period				$ 55,000

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Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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-Name Accounting Standards Codification
-Topic 470
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