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Stock-Based Awards - Summary of Assumptions Used for Estimating the Fair Value of Stock Options Granted (Details)
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]        
Expected stock price volatility, minimum 110.60% 106.90% 103.80% 103.10%
Expected stock price volatility, maximum 110.80% 111.50% 111.20% 111.50%
Risk-free interest rate, minimum 3.00% 0.80% 1.60% 0.60%
Risk-free interest rate, maximum 3.60% 1.00% 3.60% 1.20%
Expected dividend yield 0.00% 0.00% 0.00% 0.00%
Minimum        
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]        
Expected term of options (in years)   5 years 3 months 18 days 5 years 3 months 18 days 5 years 3 months 18 days
Maximum        
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]        
Expected term of options (in years) 6 years 1 month 6 days 6 years 1 month 6 days 6 years 1 month 6 days 6 years 1 month 6 days