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Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-in Capital
Accumulated Other Comprehensive Loss
Retained Earnings (Accumulated Deficit)
Beginning balance at Dec. 31, 2020 $ 716,852 $ 13 $ 1,385,301 $ (1,278) $ (667,184)
Beginning balance (in shares) at Dec. 31, 2020   127,416,740      
Issuance of common stock in connection with a collaboration agreement 85,213   85,213    
Issuance of common stock in connection with a collaboration agreement (in shares)   1,924,927      
Issuance of common stock to settle a contingent consideration 1,860   1,860    
Issuance of common stock to settle a contingent consideration (in shares)   42,737      
Vesting of restricted common stock (in shares)   89,261      
Exercise of stock options 9,635   9,635    
Exercise of stock option (in shares)   1,352,457      
Stock-based compensation 59,413   59,413    
Other comprehensive income (loss) (29)     (29)  
Net income 3,330       3,330
Ending balance at Sep. 30, 2021 876,274 $ 13 1,541,422 (1,307) (663,854)
Ending balance (in shares) at Sep. 30, 2021   130,826,122      
Beginning balance at Jun. 30, 2021 737,325 $ 13 1,512,928 (1,334) (774,282)
Beginning balance (in shares) at Jun. 30, 2021   130,479,975      
Issuance of common stock to settle a contingent consideration 1,860   1,860    
Issuance of common stock to settle a contingent consideration (in shares)   42,737      
Vesting of restricted common stock (in shares)   1,852      
Exercise of stock options 3,690   3,690    
Exercise of stock option (in shares)   301,558      
Stock-based compensation 22,944   22,944    
Other comprehensive income (loss) 27     27  
Net income 110,428       110,428
Ending balance at Sep. 30, 2021 876,274 $ 13 1,541,422 (1,307) (663,854)
Ending balance (in shares) at Sep. 30, 2021   130,826,122      
Beginning balance at Dec. 31, 2021 $ 1,431,849 $ 13 1,571,535 (1,099) (138,600)
Beginning balance (in shares) at Dec. 31, 2021 131,161,404 131,161,404      
Issuance of common stock in connection with a collaboration agreement $ 28,462   28,462    
Issuance of common stock in connection with a collaboration agreement (in shares)   881,365      
Issuance of common stock under employee stock purchase plan 2,066   2,066    
Issuance of common stock under employee stock purchase plan (Shares)   94,175      
Vesting of restricted common stock (in shares)   323,700      
Exercise of stock options 3,602   3,602    
Exercise of stock option (in shares)   566,714      
Stock-based compensation 77,217   77,217    
Other comprehensive income (loss) (10,781)     (10,781)  
Net income 617,440       617,440
Ending balance at Sep. 30, 2022 $ 2,149,855 $ 13 1,682,882 (11,880) 478,840
Ending balance (in shares) at Sep. 30, 2022 133,027,358 133,027,358      
Beginning balance at Jun. 30, 2022 $ 1,952,012 $ 13 1,656,024 (7,553) 303,528
Beginning balance (in shares) at Jun. 30, 2022   132,597,812      
Vesting of restricted common stock (in shares)   53,102      
Exercise of stock options 2,044   2,044    
Exercise of stock option (in shares)   376,444      
Stock-based compensation 24,814   24,814    
Other comprehensive income (loss) (4,327)     (4,327)  
Net income 175,312       175,312
Ending balance at Sep. 30, 2022 $ 2,149,855 $ 13 $ 1,682,882 $ (11,880) $ 478,840
Ending balance (in shares) at Sep. 30, 2022 133,027,358 133,027,358