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Stock-Based Awards (Tables) | 9 Months Ended
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Sep. 30, 2023
Share-Based Payment Arrangement [Abstract] |
Summary of Assumptions Used for Estimating the Fair Value of Stock Options Granted | The fair value of stock options granted to employees was estimated on the date of grant using the Black-Scholes option-pricing model with the following assumptions:
| Three Months Ended September 30, |  | Nine Months Ended September 30,
| 2023 |  | 2022 |  | 2023 |  | 2022
Expected term of options (in years) | 6.1 |  | 6.1 |  | 5.5 - 6.1 |  | 5.3 - 6.1
Expected stock price volatility | 99.9% - 100.9% |  | 110.6% - 110.8% |  | 99.6% - 101.5% |  | 103.8% - 111.2%
Risk-free interest rate | 4.0% - 4.4% |  | 3.0% - 3.6% |  | 3.4% - 4.4% |  | 1.6% - 3.6%
Expected dividend yield | — |  | — |  | — |  | —
Summary of Stock-based Compensation Expense | The following table sets forth the total stock-based compensation expense for all awards granted to employees and non-employees and the ESPP in the unaudited condensed consolidated statements of operations:
| Three Months Ended September 30, |  | Nine Months Ended September 30,
| 2023 |  | 2022 |  | 2023 |  | 2022
| (in thousands)
Research and development | $ | 15,819 |  |  | $ | 12,607 |  |  | $ | 46,284 |  |  | $ | 39,791 |
Selling, general and administrative | 11,125 |  |  | 12,207 |  |  | 36,760 |  |  | 37,426 |
Total stock-based compensation | $ | 26,944 |  |  | $ | 24,814 |  |  | $ | 83,044 |  |  | $ | 77,217 |

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- Definition Tabular disclosure of cost recognized for award under share-based payment arrangement by plan. Includes, but is not limited to, related tax benefit. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (f)(2) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
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