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Share-Based Compensation (Tables) | 6 Months Ended
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Jun. 30, 2021
Share-based Payment Arrangement [Abstract] |
Share-based Compensation Expense | The Company recognized share-based compensation in its Condensed Consolidated Statements of Operations and Comprehensive Loss during 2021 and 2020 as follows:
| Three Months Ended June 30, |  | Six Months Ended June 30,
| 2021 |  | 2020 |  | 2021 |  | 2020
Manufacture and supply | $ | 71 |  |  | $ | 72 |  |  | $ | 153 |  |  | $ | 135 |
Research and development | 208 |  |  | 183 |  |  | 440 |  |  | 365 |
Selling, general and administrative | 1,442 |  |  | 1,510 |  |  | 2,635 |  |  | 3,125 |
Total share-based compensation expenses | $ | 1,721 |  |  | $ | 1,765 |  |  | $ | 3,228 |  |  | $ | 3,625 |
Share-based compensation from: |  |  |  |  |  |  |
Restricted stock units | $ | 43 |  |  | $ | 309 |  |  | $ | 81 |  |  | $ | 773 |
Stock options | 1,667 |  |  | 1,445 |  |  | 3,136 |  |  | 2,841 |
Employee stock purchase plan | 11 |  |  | 11 |  |  | 11 |  |  | 11 |
Total share-based compensation expenses | $ | 1,721 |  |  | $ | 1,765 |  |  | $ | 3,228 |  |  | $ | 3,625 |
Restricted Stock Units Awards | The following tables provide information about the Company’s restricted stock unit and stock option activity during the six-month period ended June 30, 2021:
Restricted Stock Unit Awards (RSUs): | Number of Units |  | Weighted Average Grant Date Fair Value
| (in thousands) |  |
Unvested as of December 31, 2020 | 14 |  |  | $ | 11.38 |
Granted | — |  |  | — |
Vested | (4) |  |  | $ | 7.54 |
Forfeited | (2) |  |  | $ | 13.00 |
Unvested as of June 30, 2021 | 8 |  |  | $ | 13.00 |
Grant date fair value of shares vested during the period | $ | 30 |  |  |
Unrecognized compensation costs as of June 30, 2021 | $ | 1 |  |  |
Stock Option Activity | Unrecognized compensation costs related to awards of RSUs are expected to be recognized over a weighted-average period of less than one year.
Stock Option Awards: | Number of Options |  | Weighted Average Exercise Price |  |
| (in thousands) |  |  |  |
Outstanding as of December 31, 2020 | 3,259 |  |  | $ | 8.14 |  |  |
Granted | 1,211 |  |  | $ | 4.73 |  |  |
Exercised, Forfeited, Expired | (39) |  |  | $ | 5.63 |  |  |
Outstanding as of June 30, 2021 | 4,431 |  |  | $ | 7.23 |  |  |
Vested and expected to vest as of June 30, 2021 | 4,246 |  |  | $ | 7.34 |  |  |
Exercisable as of June 30, 2021 | 1,824 |  |  | $ | 9.92 |  |  |
Valuation Assumptions for Determination of Fair Value of Options | The fair values of stock options granted during the six months ended June 30, 2021 were estimated using the Black-Scholes pricing model based on the following assumptions:
Expected dividend yield | — | %
Expected volatility | 95% - 100%
Expected term (years) | 6.1
Risk-free interest rate | 1.0 | %

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