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Share-Based Compensation - Expense (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2022 | Dec. 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Total share-based compensation expenses | $ 4,381 | $ 6,819
Restricted Stock Units |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Total share-based compensation expenses | 127 | 81
Stock Options |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Total share-based compensation expenses | 4,244 | 6,714
Employee Stock Purchase Plan |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Total share-based compensation expenses | 10 | 24
Manufacture and supply |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Total share-based compensation expenses | 203 | 313
Research and development |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Total share-based compensation expenses | 672 | 881
Selling, general and administrative |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Total share-based compensation expenses | $ 3,506 | $ 5,625

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- Definition Amount of expense for award under share-based payment arrangement. Excludes amount capitalized. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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