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Collaborations - Additional Information (Detail) - USD ($)			1 Months Ended	3 Months Ended
	Apr. 02, 2015	Jun. 16, 2013	Mar. 31, 2017	Mar. 31, 2017	Mar. 31, 2016	Dec. 08, 2016
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Contract revenue				$ 271,000	$ 109,000
Pfizer Inc
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Effective termination notice period	60 days
Pfizer Inc | Collaboration Agreement | Maximum
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Contingent cash payments upon achievement of clinical, regulatory and commercial milestones						$ 17,500,000
ISU Abxis
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Contract revenue				300,000	100,000
Deferred revenue			$ 300,000	$ 300,000	$ 600,000
Deferred revenue recognition period				4 years
Milestone payment received			$ 200,000
ISU Abxis | Up Front Payment
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Amount received for research and development process		$ 1,750,000

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 225
-SubTopic 10
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Reference 1: http://www.xbrl.org/2003/role/presentationRef
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Reference 1: http://www.xbrl.org/2003/role/presentationRef
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