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Condensed Consolidated Statements of Operations (Unaudited) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2017	Mar. 31, 2016
Income Statement [Abstract]
Contract revenue	$ 271	$ 109
Operating expenses:
Research and development	2,061	2,286
General and administrative	2,381	2,395
Total operating expenses	4,442	4,681
Loss from operations	(4,171)	(4,572)
Interest and other income, net	33	980
Net loss	$ (4,138)	$ (3,592)
Net loss per common share, basic and diluted	$ (4.57)	$ (4.71)
Shares used to compute net loss per common share, basic and diluted	906,048	762,007

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