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Subsequent Events - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
 3 Months Ended
May 04, 2017
Apr. 12, 2017
Apr. 03, 2017
Mar. 31, 2017
Dec. 31, 2016
Subsequent Event [Line Items]          
Proceeds from issuance of common stock, net of issuance costs       $ 1,782  
Common stock, shares outstanding       1,000,036 801,756
Preferred stock, shares outstanding       0 0
Options to purchase aggregate shares of common stock       93,959  
Options to purchase aggregate shares of common stock, weighted-average exercise price       $ 120.00 $ 127.56
Options to purchase aggregate shares of common stock, weighted-average exercise price       143.44  
Redeemable Convertible Promissory Notes          
Subsequent Event [Line Items]          
Redeemable convertible notes, conversion per share price       $ 137.85  
Common Stock          
Subsequent Event [Line Items]          
Issuance of stock, shares       198,280  
Subsequent Event          
Subsequent Event [Line Items]          
Proceeds from issuance of common stock, net of issuance costs   $ 18,700      
Warrants to purchase common stock   2,070,000      
Warrants exercise price   $ 5.50      
Subsequent Event | Overallotment Option          
Subsequent Event [Line Items]          
Warrants to purchase common stock   270,000      
Subsequent Event | Public Offering          
Subsequent Event [Line Items]          
Warrants exercise price $ 5.50        
Common stock, shares outstanding 4,260,561        
Subsequent Event | Public Offering | 2015 Stock Incentive Plan          
Subsequent Event [Line Items]          
Options to purchase aggregate shares of common stock 44,670        
Subsequent Event | Public Offering | Other Warrants to Purchase Common Stock          
Subsequent Event [Line Items]          
Warrants exercise price $ 145.11        
Subsequent Event | Public Offering | Other Options to Purchase Common Stock          
Subsequent Event [Line Items]          
Warrants to purchase common stock 12,039        
Subsequent Event | Public Offering | Other Options to Purchase Common Stock | 2015 Stock Incentive Plan          
Subsequent Event [Line Items]          
Options to purchase aggregate shares of common stock 80,619        
Options to purchase aggregate shares of common stock, weighted-average exercise price $ 58.65        
Options to purchase aggregate shares of common stock, weighted-average exercise price $ 154.01        
Subsequent Event | Public Offering | Redeemable Convertible Promissory Notes          
Subsequent Event [Line Items]          
Redeemable convertible promissory notes convertible into share $ 11,000        
Redeemable convertible notes, conversion per share price $ 137.85        
Subsequent Event | Series A Preferred Stock          
Subsequent Event [Line Items]          
Issuance of stock, shares   13,350      
Conversion of redeemable convertible notes to common stock   200      
Subsequent Event | Series A Preferred Stock | Public Offering          
Subsequent Event [Line Items]          
Preferred stock, shares outstanding 5,750        
Subsequent Event | Common Stock          
Subsequent Event [Line Items]          
Issuance of stock, shares   1,470,000      
Subsequent Event | Common Stock | Overallotment Option          
Subsequent Event [Line Items]          
Issuance of stock, shares   540,000      
Subsequent Event | Common Stock | Public Offering          
Subsequent Event [Line Items]          
Warrants to purchase common stock 2,041,075        
Subsequent Event | Common Stock | Series A Preferred Stock | Public Offering          
Subsequent Event [Line Items]          
Conversion of redeemable convertible notes to common stock 1,150,000        
Capital on Demand Sales Agreement with Jones Trading Institutional Services LLC          
Subsequent Event [Line Items]          
Issuance of stock, shares       198,280  
Proceeds from issuance of common stock, net of issuance costs       $ 1,800  
Capital on Demand Sales Agreement with Jones Trading Institutional Services LLC | Subsequent Event          
Subsequent Event [Line Items]          
Issuance of stock, shares     241,600    
Proceeds from issuance of common stock, net of issuance costs     $ 3,500