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Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2017
Income Tax Disclosure [Abstract] |
Reconciliation of Federal Income Tax Rate to Company's Effective Tax Rate | The reconciliation of the federal statutory income tax rate to the Company’s effective tax rate for the years ended December 31, 2017 and 2016 are as follows:
|  | Year Ended December 31, |
|  | 2017 |  |  | 2016 |
Tax at statutory federal rate |  |  | -34.00 | % |  |  | -34.00 | %
State Tax (benefit)—net of federal benefit |  |  | 0.00 | % |  |  | -1.12 | %
Permanent differences |  |  | 0.60 | % |  |  | -7.95 | %
R&D credits |  |  | -1.64 | % |  |  | -3.16 | %
Derecognition due to Sec. 382 and 383 limitations |  |  | 54.08 | % |  |  | 0.00 | %
Change in valuation allowance |  |  | -52.90 | % |  |  | 46.66 | %
Federal tax rate change |  |  | 33.89 | % |  |  | 0.00 | %
Other |  |  | -0.03 | % |  |  | -0.43 | %
Effective tax rate |  |  | — |  |  |  | — |
Components of the Company's Deferred Tax Assets (Liabilities) | Significant components of the Company’s deferred tax assets as of December 31, 2017 and 2016 consist of the following (in thousands):
|  | Year Ended December 31, |
|  | 2017 |  |  | 2016 |
Deferred tax assets: |  |  |  |  |  |  |  |
Accruals and reserves |  | $ | 1,112 |  |  | $ | 1,137 |
Net operating loss carry forwards |  |  | 11,519 |  |  |  | 25,944 |
R&D tax credit carry forwards |  |  | 3,545 |  |  |  | 3,174 |
Fixed and intangible assets |  |  | 89 |  |  |  | 114 |
Valuation Allowance |  |  | (16,265 | ) |  |  | (30,369 | )
Net deferred tax assets: |  | $ | — |  |  | $ | — |
Unrecognized Tax Benefits | A reconciliation of the beginning and ending balance of the unrecognized tax benefits is as follows (in thousands):
Beginning Balance at January 1, 2016 |  | $ | 1,314 |
Increase/(Decrease) of unrecognized tax benefits taken in prior years |  |  | 6 |
Increase/(Decrease) of unrecognized tax benefits related to current year |  |  | 219 |
Ending Balance at December 31, 2016 |  | $ | 1,539 |
Increase/(Decrease) of unrecognized tax benefits taken in prior years |  |  | (126 | )
Increase/(Decrease) of unrecognized tax benefits related to current year |  |  | 62 |
Ending Balance at December 31, 2017 |  | $ | 1,475 |

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- Definition Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=84230637&loc=d3e32537-109319 + Details
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- Definition Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=84230637&loc=d3e32687-109319 + Details
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- Definition Tabular disclosure of the change in unrecognized tax benefits. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 55 -Paragraph 217 -URI http://asc.fasb.org/extlink&oid=96868398&loc=d3e36027-109320 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 15A -URI http://asc.fasb.org/extlink&oid=84230637&loc=SL6600010-109319 + Details
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