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Fair Values of Stock Options Estimated Using Black-Scholes Valuation Model (Detail)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Employee Stock Option    
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Black Scholes Method Used [Line Items]    
Expected term / Contractual Life (in years) 6 years 10 days 6 years 1 month 20 days
Risk-free interest rate 2.03% 1.53%
Dividend yield 0.00% 0.00%
Volatility 110.29% 76.59%
Non Employee Stock Option    
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Black Scholes Method Used [Line Items]    
Expected term / Contractual Life (in years) 9 years 5 months 23 days 9 years 8 months 26 days
Risk-free interest rate 2.35% 2.39%
Dividend yield 0.00% 0.00%
Volatility 111.55% 101.12%