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Related Parties - Additional Information (Detail) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Mosaic | Strategic Research Collaboration to Develop Intravitreal Anti-Complement Factor 3 (C3) Products    
Related Party Transaction [Line Items]    
Expenses related to collaboration $ 0.2 $ 0.0