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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Operating Activities    
Net loss $ (5,042) $ (4,138)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 606 120
Depreciation and amortization 33 48
Loss on disposal of assets 116  
Changes in operating assets and liabilities:    
Prepaid and other current assets (407) (279)
Accounts payable 690 62
Accrued compensation and other accrued liabilities (1,225) (26)
Deferred rent 128 (8)
Deferred revenue (6) (71)
Net cash flows used in operating activities (5,107) (4,292)
Investing Activities    
Proceeds from maturities of short-term investments 13,937 6,801
Purchase of investments (12,936)  
Purchases of property and equipment (198) (3)
Net cash flows provided by investing activities 803 6,798
Financing Activities    
Payments for the redemption of redeemable convertible notes (5,082) (6,752)
Proceeds from issuance of common stock, net of issuance costs 106,761 1,782
Proceeds from exercise of warrants 9,545  
Net cash flow provided by (used in) financing activities 111,224 (4,970)
Net increase (decrease) in cash, cash equivalents and restricted cash 106,920 (2,464)
Cash, cash equivalents and restricted cash at beginning of the period 19,805 29,857
Cash, cash equivalents and restricted cash at end of the period [1] 126,725 27,393
Supplemental Disclosure of Non-Cash Investing and Financing Activities:    
Adoption of ASC 606 207  
Conversion of redeemable convertible notes to common stock 3  
Unrealized Gain/Loss on investments $ 4 $ 1
[1] (a) The following table provides a reconciliation of cash and restricted cash to amounts reported within the condensed consolidated balance sheets: Cash and cash equivalents $126,550 $14,533 Restricted cash 175 12,860 Total cash and restricted cash $126,725 $27,393