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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Operating Activities    
Net loss $ (11,524) $ (10,015)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 1,156 231
Depreciation and amortization 70 91
Loss on disposal of assets 116  
Changes in operating assets and liabilities:    
Prepaid and other current assets (1,469) 102
Accounts payable (613) (336)
Accrued compensation and other accrued liabilities (393) 734
Deferred rent 143 (19)
Deferred revenue (6) 518
Net cash flows used in operating activities (12,520) (8,694)
Investing Activities    
Proceeds from maturities of short-term investments 30,693 6,800
Purchase of short-term investments (102,330)  
Purchases of property and equipment (201) (3)
Net cash flows (used in) provided by investing activities (71,838) 6,797
Financing Activities    
Payments for the redemption of redeemable convertible notes (5,082) (13,633)
Proceeds from issuance of common stock, net of issuance costs 106,762 5,336
Proceeds from issuance of preferred stock, common stock and warrants for follow-on offering, net of issuance costs   18,563
Proceeds from exercise of stock options 36  
Proceeds from exercise of warrants 9,545 159
Net cash flow provided by financing activities 111,261 10,425
Net increase in cash, cash equivalents and restricted cash 26,903 8,528
Cash, cash equivalents and restricted cash at beginning of the period 19,805 29,857
Cash, cash equivalents and restricted cash at end of the period [1] 46,708 38,385
Supplemental Disclosure of Non-Cash Investing and Financing Activities:    
Deemed dividend for convertible preferred stock beneficial conversion feature   3,951
Adoption of ASC 606 207  
Conversion of redeemable convertible notes to common stock 3  
Unrealized gain on investments $ 4 $ 1
[1] (a) The following table provides a reconciliation of cash and restricted cash to amounts reported within the condensed consolidated balance sheets: Cash and cash equivalents $46,533 $32,388 Restricted cash 175 5,997 Total cash and restricted cash $46,708 $38,385