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Stockholders' Equity - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands |  |  |  | 9 Months Ended |
--- | --- | --- | --- | --- | ---
Feb. 15, 2018 | Feb. 13, 2018 | Apr. 12, 2017 | Sep. 30, 2018 | Sep. 30, 2017 | Dec. 31, 2017
Stockholders Equity Disclosure [Line Items] |  |  |  |  |  |
Warrants to purchase common stock |  |  | 2,070,000 |  |  |
Warrants exercise price |  |  | $ 5.50 | $ 145.11 |  | $ 6.46
Net proceeds from sale of common stock | $ 106,800 |  | $ 18,600 | $ 106,762 | $ 5,336 |
Preferred stock, shares issued |  |  |  | 0 |  | 3,680
Preferred stock, shares outstanding |  |  |  | 0 |  | 3,680
Proceeds allocated to warrants, net |  |  | $ 5,000 |  |  |
Number of warrants outstanding |  |  |  | 12,039 |  | 1,751,708
Overallotment Option |  |  |  |  |  |
Stockholders Equity Disclosure [Line Items] |  |  |  |  |  |
Warrants to purchase common stock |  |  | 270,000 |  |  |
April 2017 Underwritten Public Offering |  |  |  |  |  |
Stockholders Equity Disclosure [Line Items] |  |  |  |  |  |
Number of warrants outstanding |  |  |  | 0 |  |
Series A Preferred Stock |  |  |  |  |  |
Stockholders Equity Disclosure [Line Items] |  |  |  |  |  |
Issuance of stock, shares |  |  | 13,350 |  |  |
Conversion of each preferred stock to common stock |  |  | 200 |  |  |
Number of shares converted |  |  |  | 3,680 | 7,850 |
Preferred stock, shares issued |  |  |  | 0 |  |
Preferred stock, shares outstanding |  |  |  | 0 | 5,500 |
Common Stock |  |  |  |  |  |
Stockholders Equity Disclosure [Line Items] |  |  |  |  |  |
Issuance of stock, shares | 3,382,352 |  | 1,470,000 |  |  |
Conversion of preferred stock to common stock |  |  |  | 736,000 | 1,570,000 |
Firm commitment underwritten public offering shares |  | 2,941,176 |  |  |  |
Common stock price, per share | $ 34.00 |  |  |  |  |
Common Stock | Overallotment Option |  |  |  |  |  |
Stockholders Equity Disclosure [Line Items] |  |  |  |  |  |
Issuance of stock, shares | 441,176 |  | 540,000 |  |  |

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