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Summary of Stock-Based Compensation Recognized (Detail) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total stock-based compensation $ 702 $ 325 $ 1,858 $ 556
Research and development        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total stock-based compensation 161 62 413 97
General and Administrative        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total stock-based compensation [1] $ 541 $ 263 $ 1,445 $ 459
[1] 2018 includes $0.1 million in modification stock-based compensation expense related to a Board member’s departure.