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Fair Values of Stock Options Estimated Using Black-Scholes Valuation Model (Detail) - Employee Stock Option - $ / shares
9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Black Scholes Method Used [Line Items]    
Risk-free interest rate 2.66% 2.02%
Expected term (in years) 5 years 11 months 19 days 5 years 11 months 26 days
Dividend yield 0.00% 0.00%
Volatility 93.60% 110.42%
Weighted-average fair value of stock options granted $ 10.28 $ 3.79