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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Operating Activities    
Net loss $ (19,218) $ (15,808)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 1,866 556
Depreciation and amortization 106 132
Loss on disposal of assets 116  
Changes in operating assets and liabilities:    
Prepaid and other current assets (2,429) 89
Accounts payable (378) 623
Accrued compensation and other accrued liabilities 234 614
Deferred rent 167 (29)
Deferred revenue (6) 200
Net cash flows used in operating activities (19,542) (13,623)
Investing Activities    
Proceeds from maturities of short-term investments 60,337 6,800
Purchase of short-term investments (135,612) (16,474)
Purchases of property and equipment (201) (3)
Net cash flows used in investing activities (75,476) (9,677)
Financing Activities    
Payments for the redemption of redeemable convertible notes (5,082) (13,915)
Proceeds from issuance of common stock, net of issuance costs 106,762 5,336
Proceeds from issuance of preferred stock, common stock and warrants for follow-on offering, net of issuance costs   18,563
Proceeds from exercise of stock options 36  
Proceeds from exercise of warrants 9,545 159
Net cash flow provided by financing activities 111,261 10,143
Net increase (decrease) in cash, cash equivalents and restricted cash 16,243 (13,157)
Cash, cash equivalents and restricted cash at beginning of the period 19,805 29,857
Cash, cash equivalents and restricted cash at end of the period [1] 36,048 16,700
Supplemental Disclosure of Non-Cash Investing and Financing Activities:    
Deemed dividend for convertible preferred stock beneficial conversion feature   3,951
Adoption of ASC 606 207  
Conversion of redeemable convertible notes to common stock 3  
Unrealized (loss) gain on investments $ (24) $ 1
[1] (a) The following table provides a reconciliation of cash and restricted cash to amounts reported within the condensed consolidated balance sheets: Cash and cash equivalents $35,998 $10,973 Restricted cash 50 5,727 Total cash and restricted cash $36,048 $16,700