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Commitments and Contingencies - Additional Information (Detail)	9 Months Ended
	Sep. 30, 2018 USD ($) ft²	Aug. 10, 2018 ft²	Dec. 08, 2016 USD ($)	May 20, 2016 USD ($)
Commitments And Contingencies Disclosure [Line Items]
Operating lease expiration date	2018-02
South San Francisco, California | New Office Lease Agreement
Commitments And Contingencies Disclosure [Line Items]
Leased area | ft²	8,606
Operating lease term of contract	5 years 2 months
Operating lease commencement date	Feb. 16, 2018
South San Francisco, California | Office Lease Agreement
Commitments And Contingencies Disclosure [Line Items]
Leased area | ft²		4,626
Pfizer Inc | Collaboration Agreement
Commitments And Contingencies Disclosure [Line Items]
Milestone payment	$ 1,000,000
Pfizer Inc | Collaboration Agreement | Maximum
Commitments And Contingencies Disclosure [Line Items]
Contingent cash payments upon achievement of clinical, regulatory and commercial milestones			$ 17,500,000
AGC Biologics, Inc | MarzAA
Commitments And Contingencies Disclosure [Line Items]
Contractual obligation payments	300,000			$ 3,800,000
Accrued liabilities	300,000
AGC Biologics, Inc | Dalcinonacog alfa (“DalcA”)
Commitments And Contingencies Disclosure [Line Items]
Contractual obligation payments	$ 3,900,000			$ 5,600,000

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Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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-Name Accounting Standards Codification
-Topic 942
-SubTopic 210
-Section S99
-Paragraph 1
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Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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